Search of human proteins with 131412225

Search of human proteins with 131412225

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|131412225 keratin 13 isoform a [Homo sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|131412225 keratin 13 isoform a [Homo sapiens]                      899   0.0  
gi|131412228 keratin 13 isoform b [Homo sapiens]                      819   0.0  
gi|24430190 keratin 15 [Homo sapiens]                                 638   0.0  
gi|24430192 keratin 16 [Homo sapiens]                                 552   e-157
gi|15431310 keratin 14 [Homo sapiens]                                 547   e-156
gi|4557701 keratin 17 [Homo sapiens]                                  494   e-140
gi|195972866 keratin 10 [Homo sapiens]                                489   e-138
gi|24234699 keratin 19 [Homo sapiens]                                 472   e-133
gi|4557699 keratin 12 [Homo sapiens]                                  463   e-130
gi|192807292 keratin 24 [Homo sapiens]                                450   e-126
gi|55956899 keratin 9 [Homo sapiens]                                  431   e-121
gi|153945736 keratin 27 [Homo sapiens]                                418   e-117
gi|114431246 keratin 25D [Homo sapiens]                               403   e-112
gi|31559829 keratin 25 [Homo sapiens]                                 390   e-108
gi|94538345 keratin 35 [Homo sapiens]                                 378   e-105
gi|4504927 keratin 36 [Homo sapiens]                                  377   e-104
gi|31559815 keratin 26 [Homo sapiens]                                 367   e-101
gi|27894337 keratin 20 [Homo sapiens]                                 362   e-100
gi|116488398 keratin 32 [Homo sapiens]                                357   2e-98
gi|14917117 keratin 33A [Homo sapiens]                                354   1e-97
gi|14917115 keratin 31 [Homo sapiens]                                 352   5e-97
gi|10337581 type I hair keratin 3B [Homo sapiens]                     347   1e-95
gi|14917119 keratin 34 [Homo sapiens]                                 343   2e-94
gi|40354195 keratin 18 [Homo sapiens]                                 323   3e-88
gi|4557888 keratin 18 [Homo sapiens]                                  323   3e-88
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  322   6e-88
gi|15431318 keratin 38 [Homo sapiens]                                 318   8e-87
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  313   3e-85
gi|55770882 keratin 37 [Homo sapiens]                                 313   3e-85
gi|27894339 keratin 23 [Homo sapiens]                                 308   5e-84

>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  899 bits (2323), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
           MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG
Sbjct: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60

Query: 61  FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE 120
           FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE
Sbjct: 61  FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE 120

Query: 121 KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI 180
           KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI
Sbjct: 121 KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI 180

Query: 181 DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK 240
           DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK
Sbjct: 181 DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK 240

Query: 241 KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS 300
           KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS
Sbjct: 241 KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS 300

Query: 301 AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL 360
           AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL
Sbjct: 301 AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL 360

Query: 361 QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFP 420
           QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFP
Sbjct: 361 QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFP 420

Query: 421 SSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP 458
           SSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP
Sbjct: 421 SSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP 458


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  819 bits (2116), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
           MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG
Sbjct: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60

Query: 61  FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE 120
           FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE
Sbjct: 61  FGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLE 120

Query: 121 KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI 180
           KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI
Sbjct: 121 KVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEI 180

Query: 181 DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK 240
           DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK
Sbjct: 181 DNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMK 240

Query: 241 KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS 300
           KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS
Sbjct: 241 KNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS 300

Query: 301 AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL 360
           AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL
Sbjct: 301 AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQL 360

Query: 361 QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
           QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK
Sbjct: 361 QQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  638 bits (1646), Expect = 0.0
 Identities = 333/440 (75%), Positives = 365/440 (82%), Gaps = 21/440 (4%)

Query: 13  GGGFGGGSCQLGGG-RGVSTCSTRFVSGGSAGGYGGGVS-CGFGGGAGSGFGGGYGGGLG 70
           GGGFGGGS   GGG R +S  S RFVS GS GGYGGG+  CGFGGGAGS FGGG+GGG+G
Sbjct: 27  GGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVG 86

Query: 71  GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130
           GG+GGG GGG               DGGLL+GNEKITMQNLNDRLASYL+KVRALEEANA
Sbjct: 87  GGFGGGFGGG---------------DGGLLSGNEKITMQNLNDRLASYLDKVRALEEANA 131

Query: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190
           DLEVKI DW+ KQ+P SPE DYS Y+KTIEELRDKI+  TI+N+RVILEIDNARLAADDF
Sbjct: 132 DLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDF 191

Query: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250
           RLKYENELALRQ VEADINGLRRVLDELTL++TDLEMQIE LNEELAY+KKNHEEEMKEF
Sbjct: 192 RLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEF 251

Query: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310
           S+Q+ GQVNVEMDA PG+DLTRVLAEMREQYEAMAE+NRRD E WF +K+ ELNKEV++N
Sbjct: 252 SSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASN 311

Query: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370
           T MIQTSKTEIT+LRRT+Q LEIELQSQLSMKAGLEN++AETECRYA QLQQIQGLI  +
Sbjct: 312 TEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGL 371

Query: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGF----PSSAGSV 426
           EAQLSELR EME QNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM G      SS G  
Sbjct: 372 EAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIGIREASSGGGG 431

Query: 427 SPRSTSVTTTSSASVTTTSN 446
           S  +  +    S      S+
Sbjct: 432 SSSNFHINVEESVDGQVVSS 451


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  552 bits (1423), Expect = e-157
 Identities = 293/453 (64%), Positives = 351/453 (77%), Gaps = 32/453 (7%)

Query: 9   SASYGGGFGGGSCQL---------------GGGRGVSTCSTRFVSGGSAG---GYGGGVS 50
           S   GGG GGGS ++               GGG  VS+   RF SGG+ G   GYGGG S
Sbjct: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS---RFSSGGACGLGGGYGGGFS 73

Query: 51  CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQN 110
                  GSGFGGGYGGGLG G+GGGLG GFGGGFAGG         GLL G+EK+TMQN
Sbjct: 74  SS--SSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGG--------DGLLVGSEKVTMQN 123

Query: 111 LNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTAT 170
           LNDRLASYL+KVRALEEANADLEVKIRDW+ +Q P S  +DYSPY+KTIE+LR+KI+ AT
Sbjct: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRP-SEIKDYSPYFKTIEDLRNKIIAAT 182

Query: 171 IENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIE 230
           IEN + IL+IDNARLAADDFR KYE+ELALRQ+VEAD+NGLRRVLDELTL++TDLEMQIE
Sbjct: 183 IENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIE 242

Query: 231 SLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRR 290
            L EELAY++KNHEEEM     Q  G VNVEMDA PG+DL+R+L EMR+QYE MAE+NRR
Sbjct: 243 GLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRR 302

Query: 291 DAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA 350
           DAE WF +K+ ELNKEV++N+ ++Q+S++E+TELRR LQGLEIELQSQLSMKA LEN++ 
Sbjct: 303 DAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLE 362

Query: 351 ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLE 410
           ET+ RY +QL QIQGLI S+E QL++LR EME Q+QEY++LLD+KTRLEQEIATYR LLE
Sbjct: 363 ETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLE 422

Query: 411 GQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTT 443
           G+DA +    +S  S S R    +++SS+S  T
Sbjct: 423 GEDAHLSSQQASGQSYSSREVFTSSSSSSSRQT 455


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  547 bits (1410), Expect = e-156
 Identities = 292/451 (64%), Positives = 346/451 (76%), Gaps = 33/451 (7%)

Query: 9   SASYGGGFGGGSCQL-----GG--------GRGVSTCSTRFVSGGS---AGGYGGGVSCG 52
           S   GGG GGGS ++     GG        G G+S  S+RF SGG+    GGYGGG S  
Sbjct: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFS-- 74

Query: 53  FGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLN 112
               + S FG G+GGG GGG G GLGGGFGGGFAGG         GLL G+EK+TMQNLN
Sbjct: 75  ---SSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGG--------DGLLVGSEKVTMQNLN 123

Query: 113 DRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIE 172
           DRLASYL+KVRALEEANADLEVKIRDW+ +Q PA   +DYSPY+KTIE+LR+KILTAT++
Sbjct: 124 DRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEI-KDYSPYFKTIEDLRNKILTATVD 182

Query: 173 NNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESL 232
           N  V+L+IDNARLAADDFR KYE EL LR SVEADINGLRRVLDELTL++ DLEMQIESL
Sbjct: 183 NANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESL 242

Query: 233 NEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDA 292
            EELAY+KKNHEEEM     QV G VNVEMDA PG+DL+R+L EMR+QYE MAE+NR+DA
Sbjct: 243 KEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDA 302

Query: 293 EEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAET 352
           EEWF  K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LEN++ ET
Sbjct: 303 EEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEET 362

Query: 353 ECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQ 412
           + RY +QL QIQ +I S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+
Sbjct: 363 KGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE 422

Query: 413 DAKMIGFPSSAGSVSPRSTSVTTTSSASVTT 443
           DA +     S+GS S R     T+SS  + T
Sbjct: 423 DAHLSSSQFSSGSQSSRD---VTSSSRQIRT 450


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  494 bits (1273), Expect = e-140
 Identities = 265/421 (62%), Positives = 319/421 (75%), Gaps = 35/421 (8%)

Query: 2   SLRLQSSSASYGG--GFGGGS----CQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGG 55
           S+R  +SS+S  G  G GGGS    C+L GG G  +C       GSAGG G  +      
Sbjct: 4   SIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-----GSAGGLGSTLG----- 53

Query: 56  GAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRL 115
             GS +   Y  G GGGYG   GG          VD      GLL G EK TMQNLNDRL
Sbjct: 54  --GSSYSSCYSFGSGGGYGSSFGG----------VD------GLLAGGEKATMQNLNDRL 95

Query: 116 ASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNR 175
           ASYL+KVRALEEAN +LEVKIRDW+ +Q+P  P RDYS YY+TIEEL++KILTAT++N  
Sbjct: 96  ASYLDKVRALEEANTELEVKIRDWYQRQAPG-PARDYSQYYRTIEELQNKILTATVDNAN 154

Query: 176 VILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEE 235
           ++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++ DLEMQIE+L EE
Sbjct: 155 ILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEE 214

Query: 236 LAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEW 295
           LAY+KKNHEEEM     QV G++NVEMDA PG+DL+R+L EMR+QYE MAE+NR+DAE+W
Sbjct: 215 LAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDW 274

Query: 296 FHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECR 355
           F +K+ ELN+EV+TN+ ++Q+ K+EI+ELRRT+Q LEIELQSQLSMKA LE  +AETE R
Sbjct: 275 FFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENR 334

Query: 356 YALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
           Y +QL QIQGLI S+E QL++LR EME QNQEYK+LLD+KTRLEQEIATYR LLEG+DA 
Sbjct: 335 YCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAH 394

Query: 416 M 416
           +
Sbjct: 395 L 395


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  489 bits (1259), Expect = e-138
 Identities = 265/432 (61%), Positives = 314/432 (72%), Gaps = 29/432 (6%)

Query: 2   SLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA---- 57
           SLR+ SS  S GGGF  G     GG      S     GGS+GGYGG    GFGGG+    
Sbjct: 33  SLRISSSKGSLGGGFSSGG--FSGGSFSRGSSGGGCFGGSSGGYGG--LGGFGGGSFRGS 88

Query: 58  --GSGFGGGYGGGLGGG------YGGGL-------GGGFGGGFAGGFVDFGACDGGLLTG 102
              S FGG YGG  GGG      +GGG        GGGFGGGF GGF      DGGLL+G
Sbjct: 89  YGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGF----GGDGGLLSG 144

Query: 103 NEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQ--SPASPERDYSPYYKTIE 160
           NEK+TMQNLNDRLASYL+KVRALEE+N +LE KI++W+ K   S     RDYS YYKTI+
Sbjct: 145 NEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTID 204

Query: 161 ELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTL 220
           +L+++IL  T +N  ++L+IDNARLAADDFRLKYENE+ALRQSVEADINGLRRVLDELTL
Sbjct: 205 DLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTL 264

Query: 221 SKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQ 280
           +K DLEMQIESL EELAY+KKNHEEEMK+  N   G VNVEM+A PG+DLT++L  MR Q
Sbjct: 265 TKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQ 324

Query: 281 YEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLS 340
           YE +AE+NR+DAE WF+ KS EL  E+  N   I + K+EITELRR +Q LEIELQSQL+
Sbjct: 325 YEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLA 384

Query: 341 MKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ 400
           +K  LE ++AETE RY +QL QIQ  IS++E QL ++R+E ECQN EY+ LLDIK RLE 
Sbjct: 385 LKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLEN 444

Query: 401 EIATYRSLLEGQ 412
           EI TYRSLLEG+
Sbjct: 445 EIQTYRSLLEGE 456



 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 46/105 (43%), Positives = 56/105 (53%), Gaps = 13/105 (12%)

Query: 5   LQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGG------AG 58
           L+   +S GGG GGGS   GGG G  +       GG  GG+GG    G+GGG      +G
Sbjct: 453 LEGEGSSGGGGRGGGS--FGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510

Query: 59  SGFG-----GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
            G+G     GG+GG   GGYGGG  GG GGG+ GG    G+  GG
Sbjct: 511 GGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG 555



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 40/84 (47%), Positives = 49/84 (58%), Gaps = 3/84 (3%)

Query: 7   SSSASYGGGFGG--GSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGG 64
           SS   +GGG GG  G    GG  G  +    +  G S+GG+GG  S G+GGG+  G GGG
Sbjct: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541

Query: 65  YGGGLGGGYGGGLGGGFGGGFAGG 88
           YGGG  GG G   GGG+GGG + G
Sbjct: 542 YGGGSSGG-GSSSGGGYGGGSSSG 564



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 40/90 (44%), Positives = 48/90 (53%), Gaps = 13/90 (14%)

Query: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
           + +RL++   +Y     G     GGGRG          G   GGYGGG S G  G +G G
Sbjct: 438 IKIRLENEIQTYRSLLEGEGSSGGGGRG---------GGSFGGGYGGGSSGG--GSSGGG 486

Query: 61  FGGGYGGGLGGGYGGGL--GGGFGGGFAGG 88
            GGG+GG  GGGYGGG   GG  GGG+ GG
Sbjct: 487 HGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 34/64 (53%), Positives = 38/64 (59%)

Query: 39  GGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
           G S GG  GG S G G G GS  GG  GGG GGG+GG  GGG+GGG +GG    G   GG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGG 516

Query: 99  LLTG 102
             +G
Sbjct: 517 SSSG 520



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 28/61 (45%), Positives = 29/61 (47%), Gaps = 14/61 (22%)

Query: 7   SSSASYGGGF-GGGSCQLGGGRGVSTCSTRFVSGG---SAGGYGGGVSCGFGGGAGSGFG 62
           SSS  YGGG  GGG    GGG           SGG   S GGYGGG S G    + SG  
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGS----------SGGGSSSGGGYGGGSSSGGHKSSSSGSV 574

Query: 63  G 63
           G
Sbjct: 575 G 575


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  472 bits (1215), Expect = e-133
 Identities = 255/422 (60%), Positives = 304/422 (72%), Gaps = 55/422 (13%)

Query: 6   QSSSASYGGGFGGGSCQLG--------------GGRGVSTCSTRFVSGGSAGGYGGGVSC 51
           QSS+ S  GG GGGS + G              GGRGVS  S RFVS  S+G YG     
Sbjct: 8   QSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYG----- 62

Query: 52  GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNL 111
                      GGYGG L                            GLL GNEK+TMQNL
Sbjct: 63  -----------GGYGGVL------------------------TASDGLLAGNEKLTMQNL 87

Query: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171
           NDRLASYL+KVRALE AN +LEVKIRDW+ KQ P  P RDYS YY TI++LRDKIL ATI
Sbjct: 88  NDRLASYLDKVRALEAANGELEVKIRDWYQKQGP-GPSRDYSHYYTTIQDLRDKILGATI 146

Query: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231
           EN+R++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++TDLEMQIE 
Sbjct: 147 ENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEG 206

Query: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291
           L EELAY+KKNHEEE+     QV GQV+VE+D+ PG DL ++L++MR QYE MAE+NR+D
Sbjct: 207 LKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKD 266

Query: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
           AE WF +++ ELN+EV+ +T  +Q S++E+T+LRRTLQGLEIELQSQLSMKA LE+T+AE
Sbjct: 267 AEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAE 326

Query: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
           TE R+  QL  IQ LIS IEAQL ++R++ E QNQEY+ L+DIK+RLEQEIATYRSLLEG
Sbjct: 327 TEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEG 386

Query: 412 QD 413
           Q+
Sbjct: 387 QE 388


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  463 bits (1191), Expect = e-130
 Identities = 253/445 (56%), Positives = 321/445 (72%), Gaps = 19/445 (4%)

Query: 8   SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGS----GFGG 63
           S++S G G+GG +   G   G          GG +     G S GFGGG+GS    G G 
Sbjct: 34  SASSVGSGYGGSAFGFGASCG----------GGFSAASMFGSSSGFGGGSGSSMAGGLGA 83

Query: 64  GYGGGLGGGYGGGLGGGFGGGFAGGFVDF-GACDGGLLTGNEKITMQNLNDRLASYLEKV 122
           GYG  LGGG  GGLG GFGG   GG +      DGGLL+G+EK TMQNLNDRLASYL+KV
Sbjct: 84  GYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKV 143

Query: 123 RALEEANADLEVKIRDWHLKQSPASPER---DYSPYYKTIEELRDKILTATIENNRVILE 179
           RALEEAN +LE KIR+W+  +   + +    DYS YY  IE+LR+KI++A+I N +++L+
Sbjct: 144 RALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQ 203

Query: 180 IDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYM 239
           IDNARLAA+DFR+KYENELALRQ VEADINGLRRVLDELTL++TDLEMQIESLNEELAYM
Sbjct: 204 IDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYM 263

Query: 240 KKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAK 299
           KKNHE+E++ F     G+V+VEMDA PG+DLTR+L +MR QYE +AE+NR+DAE WF  K
Sbjct: 264 KKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEK 323

Query: 300 SAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQ 359
           S EL KE+STNT  +Q+SK+E+T+LRR  Q LEIELQSQL+MK  LE+++AE E  Y  Q
Sbjct: 324 SGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQ 383

Query: 360 LQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGF 419
           L Q+Q LIS++EAQL ++R++ E QN +++ LL++K RLE EI TYR LL+G +A+  G 
Sbjct: 384 LSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDG-EAQGDGL 442

Query: 420 PSSAGSVSPRSTSVTTTSSASVTTT 444
             S      +S + +T SS   T T
Sbjct: 443 EESLFVTDSKSQAQSTDSSKDPTKT 467


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  450 bits (1157), Expect = e-126
 Identities = 253/476 (53%), Positives = 319/476 (67%), Gaps = 36/476 (7%)

Query: 2   SLRLQSSSASYGGGFG---GGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGV-----SC-- 51
           S R+ +  +S+  G     GGS   G   G S+CS   +SGGS+G +GG       SC  
Sbjct: 17  SARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCS---LSGGSSGAFGGSFGGGFGSCSV 73

Query: 52  --GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGG------GFAGGFVDFGAC------DG 97
             GFGG +GSG G G G   GG  G G G GF G      G  GGF  +G        DG
Sbjct: 74  GGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDG 133

Query: 98  GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPE----RDYS 153
           GL +G EK TMQNLNDRLA+YL+KVRALEEAN DLE KI++W+ K  P S +    RDYS
Sbjct: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193

Query: 154 PYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRR 213
            YY  IE+LR++I+ AT+EN  +IL IDNARLAADDFRLKYENEL LRQSVEADINGLR+
Sbjct: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253

Query: 214 VLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRV 273
           VLD+LT++++DLEMQIES  EELAY++KNHEEEMK       G+V VEM+A PG DLT++
Sbjct: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313

Query: 274 LAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEI 333
           L +MR QYE +AE+NRR+AEE F+ +SA L  ++ST+     ++K EITEL+RTLQ LEI
Sbjct: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373

Query: 334 ELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLD 393
           ELQSQL+MK+ LE T+A+TE  Y  QL +IQ  IS++E ++ ++  E +CQN EYK LLD
Sbjct: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433

Query: 394 IKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASG 449
           IKTRLE EI TYR LL+G+     G  SS      R++      S  + +  + SG
Sbjct: 434 IKTRLEVEIETYRRLLDGE-----GGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSG 484



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 15/78 (19%)

Query: 31 TCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGG-----FGGGF 85
          +CS+R  S  + G     VS G     GS F  G   GLGG    G  GG       GG 
Sbjct: 2  SCSSRASSSRAGGSSSARVSAG-----GSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGS 56

Query: 86 AGGF-----VDFGACDGG 98
          +G F       FG+C  G
Sbjct: 57 SGAFGGSFGGGFGSCSVG 74


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  431 bits (1107), Expect = e-121
 Identities = 227/420 (54%), Positives = 299/420 (71%), Gaps = 22/420 (5%)

Query: 7   SSSASYGGGF-------GGGSC--QLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGA 57
           SSS+ YGGG        GGGS     GGG G       F +    GG+GGG S GFGG +
Sbjct: 48  SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGG-----FSASSLGGGFGGG-SRGFGGAS 101

Query: 58  GSGFG--GGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGAC----DGGLLTGNEKITMQNL 111
           G G+   GG+GGG GGG GGG GGG+G GF GGF  FG      DGG+LT NEK TMQ L
Sbjct: 102 GGGYSSSGGFGGGFGGGSGGGFGGGYGSGF-GGFGGFGGGAGGGDGGILTANEKSTMQEL 160

Query: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171
           N RLASYL+KV+ALEEAN DLE KI+DW+ K+ PA+ +++YSPYY TI++L+D+I+  T+
Sbjct: 161 NSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTV 220

Query: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231
            NN+ +L+IDN R+  DDFR+K+E E  LRQ V+ADINGLR+VLD LT+ K+DLEMQ E+
Sbjct: 221 GNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYET 280

Query: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291
           L EEL  +KKNH+EEM + + Q  G VNVE++  PG DLT+ L +MR++YE +  +NR+D
Sbjct: 281 LQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKD 340

Query: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351
            E  +  +  ++  EVS++   +Q+S  E+T+LR  +Q LEIELQSQLS KA LE ++ +
Sbjct: 341 IENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED 400

Query: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411
           T+ RY  QLQ IQ  IS++EAQ++++R E+ECQNQEY +LL IK RLE+EI TY +LLEG
Sbjct: 401 TKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 49/104 (47%), Positives = 53/104 (50%), Gaps = 12/104 (11%)

Query: 13  GGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGG 72
           GGG+GGGS   GG  G S        GGS GGYGGG   G  GG+G G  GG GG  GGG
Sbjct: 503 GGGYGGGSGSRGGSGG-SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG 561

Query: 73  YG--GGLGGGFGGGFA---------GGFVDFGACDGGLLTGNEK 105
            G  GG GGG+GGG           GG   FG   GG   G E+
Sbjct: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 47/94 (50%), Positives = 49/94 (52%), Gaps = 6/94 (6%)

Query: 8   SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSA--GGYGGGVSCGFGGGAGSGFGGGY 65
           S  SYGGG  GG    GGG G    S     GGS   GG GGG   G GGG   G GGG+
Sbjct: 493 SGGSYGGGGSGGG--YGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550

Query: 66  GGGLGGGYGG--GLGGGFGGGFAGGFVDFGACDG 97
            GG GG YGG  G GGG GGG+ GG    G   G
Sbjct: 551 SGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGG 584



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 10/106 (9%)

Query: 8   SSASYGGGFGGGSCQLGG-----GRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFG 62
           S  SYGGG G G    GG     G G S  S    SGGS G YGGG   G GGG+G G+G
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG--SGSGGGSGGGYG 573

Query: 63  GGYG--GGLGGGYGGGLG-GGFGGGFAGGFVDFGACDGGLLTGNEK 105
           GG G  GG GG +GGG G GG  GG  GG  +     GG   G+ K
Sbjct: 574 GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 43/77 (55%), Positives = 46/77 (59%), Gaps = 5/77 (6%)

Query: 17  GGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCG-FGGGAGS--GFGGGYGG--GLGG 71
           G G   LGG  G      R   GGS G YGGG S G +GGG+GS  G GG YGG  G GG
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528

Query: 72  GYGGGLGGGFGGGFAGG 88
           G GGG GGG GGG +GG
Sbjct: 529 GSGGGYGGGSGGGHSGG 545



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 45/100 (45%), Positives = 49/100 (49%), Gaps = 22/100 (22%)

Query: 8   SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAG-GYGGGV--------SCGFGGGAG 58
           S  SYG G  GGS   GG  G          GG +G GYGGG         S G G G+G
Sbjct: 481 SGGSYGRGSRGGS---GGSYG----------GGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527

Query: 59  SGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
            G GGGYGGG GGG+ GG GGG  GG  G +       GG
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG 567



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 24  GGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLG--GGF 81
           GG     +     +  G  GG GG    G  GG+G  +G   GGG GGGYGGG G  GG 
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYG---GGGSGGGYGGGSGSRGGS 516

Query: 82  GGGFAGGFVDFGACDGG 98
           GG + GG    G   GG
Sbjct: 517 GGSYGGGSGSGGGSGGG 533


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  418 bits (1074), Expect = e-117
 Identities = 240/444 (54%), Positives = 302/444 (68%), Gaps = 30/444 (6%)

Query: 1   MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSG 60
           MS+R  S+S   G      SC   GG G    S R  SGG+  G+G G +CG  G  GSG
Sbjct: 1   MSVRFSSTSRRLG------SC---GGTG----SVRLSSGGA--GFGAGNTCGVPG-IGSG 44

Query: 61  FGGGYGGGLG-GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYL 119
           F   +GG    GGYGGGLGGG     A     F   + GLL+GNEK+TMQNLNDRLASYL
Sbjct: 45  FSCAFGGSSSAGGYGGGLGGGSASCAA-----FTGNEHGLLSGNEKVTMQNLNDRLASYL 99

Query: 120 EKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPYYKTIEELRDKILTATIENNRV 176
           E VRALEEANADLE KI+ W+ K  P S    + DYS Y+  I+EL+++I++AT  N  V
Sbjct: 100 ENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHV 159

Query: 177 ILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEEL 236
           +L+ DNARL ADDFRLK+ENELAL QSVEADINGLRRVLDELTL +TDLE+Q+E+L+EEL
Sbjct: 160 VLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEEL 219

Query: 237 AYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWF 296
           AY+KKNHEEEMK       G VNVEM+A PG+DLT +L  MR +YEA+AE+NRRDAE WF
Sbjct: 220 AYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWF 279

Query: 297 HAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRY 356
           + KSA L +++S +     +++ E+ E++RTLQ LEIELQS L+ K  LE ++ ETE  Y
Sbjct: 280 NEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNY 339

Query: 357 ALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQD--- 413
             QL QIQ  I ++E QL ++R+E E Q  EY+ LLDIK  LE+EI TY  L++G+D   
Sbjct: 340 CAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSC 399

Query: 414 --AKMIGFPSSAGSVSPRSTSVTT 435
             +K  G P +    S ++T V T
Sbjct: 400 SKSKGYGGPGNQTKDSSKTTIVKT 423


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  403 bits (1035), Expect = e-112
 Identities = 221/409 (54%), Positives = 286/409 (69%), Gaps = 11/409 (2%)

Query: 33  STRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDF 92
           S R ++GG+  G+ G  +CG G  AGS F    GGGLG   GG   GG  G  A   + F
Sbjct: 20  SVRPLNGGA--GFAGSSACG-GSVAGSEFSCALGGGLGSVPGGSHAGGALGNAA--CIGF 74

Query: 93  GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---E 149
              +GGLL+GNEK+TMQNLNDRLASYL+ VRALEEANA+LE KI+ W+ K  P S    +
Sbjct: 75  AGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLD 134

Query: 150 RDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADIN 209
            DYS Y+ TIE+L++KI+++T  N  VIL+IDNARLAADDFRLKYENEL L Q+VEADIN
Sbjct: 135 HDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADIN 194

Query: 210 GLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGID 269
           GLRRVLDELTL +TD E+Q ESL+EE+ Y+KKNHEEEMK       G VNVEM+A PG+D
Sbjct: 195 GLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVD 254

Query: 270 LTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQ 329
           L  +L  MR +YEA+AE+NR+DAE WF+ KSA L +++S ++     +++++TE+RRTLQ
Sbjct: 255 LAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQ 314

Query: 330 GLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYK 389
            LEI+LQS ++ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+
Sbjct: 315 TLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYE 374

Query: 390 MLLDIKTRLEQEIATYRSLLEGQD---AKMIGFPSSAGSVSPRSTSVTT 435
            LLD+K  LE+EI TY  L++G     +K  GF S +   S +  S TT
Sbjct: 375 HLLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTT 423


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  390 bits (1003), Expect = e-108
 Identities = 209/378 (55%), Positives = 265/378 (70%), Gaps = 9/378 (2%)

Query: 40  GSAGGYGGGVSCGFGGGAG-SGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98
           GS   YGGG S G G   G SG G G+    GG   GG  GG G   AG    F   + G
Sbjct: 19  GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG-GNPCAG----FTVNERG 73

Query: 99  LLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPY 155
           LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+ W+ K  P S    + DYS Y
Sbjct: 74  LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133

Query: 156 YKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVL 215
           +  I++L+++I+ +T  N   +L+IDNARL ADDFRLKYENELAL QSVEAD+NGLRRVL
Sbjct: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193

Query: 216 DELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLA 275
           DE+TL +TDLE+Q E+L+EE+ Y+KKNH+EEM+       G VNVEM+A PG+DLT +L 
Sbjct: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLN 253

Query: 276 EMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIEL 335
            MR +YEA+AE+NRRDAE WF+ KSA L +++S +     +++ E+TE++RTLQ LEIEL
Sbjct: 254 NMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIEL 313

Query: 336 QSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIK 395
           QS L+ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+ LLDIK
Sbjct: 314 QSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIK 373

Query: 396 TRLEQEIATYRSLLEGQD 413
             LE+EI TY  L+ G D
Sbjct: 374 LHLEKEIETYCLLIGGDD 391


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  378 bits (970), Expect = e-105
 Identities = 205/380 (53%), Positives = 273/380 (71%), Gaps = 9/380 (2%)

Query: 79  GGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRD 138
           GGF   ++GG   FG    G+LTGNEK TMQ+LNDRLA YLEKVR LE+ NA LE +IR+
Sbjct: 75  GGFATSYSGGGGWFGE---GILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIRE 131

Query: 139 WHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENEL 198
           W  +Q P     DY  Y++TIEEL+ K L +  EN R+++EIDNA+LAADDFR KYE E+
Sbjct: 132 WCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEV 190

Query: 199 ALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQV 258
           +LRQ VE+DINGLRR+LD+LTL K+DLE Q+ESL EEL  +KKNHEEE+     Q+  ++
Sbjct: 191 SLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRL 250

Query: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
           NVE+DA P +DL RVL EMR QYE + E NRRDAE+W   +S ELN++V +++  +Q+ +
Sbjct: 251 NVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQ 310

Query: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
            EI ELRRT+  LEIELQ+Q SM+  LE+T+AETE RY+ QL Q+Q +I+++EAQL+E+R
Sbjct: 311 AEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIR 370

Query: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSS 438
           +++E QNQEY++LLD++ RLE EI TYR LLE +D+K+   P  A   SP  + +    +
Sbjct: 371 ADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNP-CAPDYSPSKSCLPCLPA 429

Query: 439 ASVTTTSNASGRRTSDVRRP 458
           AS       S  RT+   RP
Sbjct: 430 AS----CGPSAARTNCSPRP 445


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  377 bits (968), Expect = e-104
 Identities = 214/406 (52%), Positives = 275/406 (67%), Gaps = 26/406 (6%)

Query: 31  TCSTRFVSGGSAG--GYGGGVS----------CGFGGGAGSGFGGGYGGGLGGGYGGGLG 78
           TC+  F +G   G  G  GG+S          C     AG+    GY      G  G LG
Sbjct: 5   TCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAA---GYISSARSGLSG-LG 60

Query: 79  GGFGGGF------AGGFVDFGA--CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130
               G +        GFV  G   C+G    G+EK TMQ LNDRLA+YLEKVR LE  NA
Sbjct: 61  SCLPGSYLSSECHTSGFVGSGGWFCEGSF-NGSEKETMQFLNDRLANYLEKVRQLERENA 119

Query: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190
           +LE +I++W+  Q P     DY  Y+KTIE+ + KIL    EN R++L+IDNA+LAADDF
Sbjct: 120 ELESRIQEWYEFQIPYICP-DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDF 178

Query: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250
           R KYE EL+LRQ VEADINGLRR+LDELTL K DLE Q+ESL EEL  +KKNHEEE+   
Sbjct: 179 RTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVL 238

Query: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310
             Q+  ++NVE+DA P +DL ++L +MR QYEA+ E NRRD E WF+ ++ ELN++V ++
Sbjct: 239 RCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSS 298

Query: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370
           +  +Q  +TEI ELRRT+  LEIELQ+Q SM+  LE+T+AETE RY+ QL Q+Q LIS++
Sbjct: 299 SEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNV 358

Query: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 416
           EAQLSE+R ++E QNQEY++LLD+K RLE EIATYR LLEG+D K+
Sbjct: 359 EAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKL 404


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  367 bits (941), Expect = e-101
 Identities = 207/396 (52%), Positives = 266/396 (67%), Gaps = 9/396 (2%)

Query: 24  GGGRGV-STCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFG 82
           GG R + S   +  +SGG  G   G V  G   GA S F     G   GG     GGG G
Sbjct: 7   GGSRRICSRTGSGRLSGGGTGFVAGNVCVG--SGARSSFSCTLEGISSGGSFCNSGGGLG 64

Query: 83  GGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLK 142
            G   GF+     +  LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+  + K
Sbjct: 65  SGACAGFL---GNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121

Query: 143 QSPASP---ERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199
             P S    + DYS Y+  IE+L+ +I +ATI N  ++L+ DNARL ADDFRLKYENELA
Sbjct: 122 CEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELA 181

Query: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVN 259
           L  SVEAD +GLRRVLDELTL  TDLE+Q E+L+EEL Y+KK+HEEEM+       G VN
Sbjct: 182 LHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVN 241

Query: 260 VEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKT 319
           VEM+ATPG+DLT +L  MR +YE +AE+NR+DAE WF+ +SA L +++S +      ++ 
Sbjct: 242 VEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301

Query: 320 EITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRS 379
           E+TEL+R LQ LEIELQS +++K   E ++AETE  Y  QLQQIQ  I  +E QL ++R+
Sbjct: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRT 361

Query: 380 EMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
           E E Q  EY+ LLD+K  LE+EI  Y +LL+G++ K
Sbjct: 362 ETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  362 bits (929), Expect = e-100
 Identities = 188/346 (54%), Positives = 255/346 (73%), Gaps = 4/346 (1%)

Query: 73  YGGGLGGGFGGGFAGGFVDFGAC---DGGLLTGNEKITMQNLNDRLASYLEKVRALEEAN 129
           YGG  G G     +   V++G+     G L  GNEK+ MQNLNDRLASYLEKVR LE++N
Sbjct: 36  YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95

Query: 130 ADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADD 189
           + LEV+I+ W+   +P +  RDYS YY+ IEELR +I  A ++N R +L+IDNA+LAA+D
Sbjct: 96  SKLEVQIKQWYETNAPRAG-RDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAED 154

Query: 190 FRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKE 249
           FRLKYE E  +R +VEAD+ GL +V D+LTL KTDLE+QIE LN++LA +KK H+EE+  
Sbjct: 155 FRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDG 214

Query: 250 FSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVST 309
               +   VNVE+DA PG++L  ++ EMR++YE MA++N ++A+E F  ++A L ++V+ 
Sbjct: 215 LHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTV 274

Query: 310 NTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISS 369
           NT  ++ ++ ++TELRRT Q LEIELQS LSMK  LE+T+ ET+ RY+ QL  +Q L+SS
Sbjct: 275 NTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSS 334

Query: 370 IEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
           +EAQL ++RS ME QN EY +LLDIKTRLEQEIATYR LLEG+D K
Sbjct: 335 LEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  357 bits (915), Expect = 2e-98
 Identities = 186/329 (56%), Positives = 249/329 (75%), Gaps = 3/329 (0%)

Query: 98  GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW-HLKQSPASPERDYSPYY 156
           G   GNEK TMQ LNDRLASYL +VR LE+ NA+LE +I++  H +    +P  DY  ++
Sbjct: 90  GAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTP--DYQSHF 147

Query: 157 KTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLD 216
           +TIEEL+ KIL    EN R+++ IDNA+LAADDFR KYE ELA+RQ VEADINGLRR+LD
Sbjct: 148 RTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILD 207

Query: 217 ELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAE 276
           +LTL K DLE Q+ESL EEL  +KKNHEEE+     Q+  ++N+E+DA P +DLTRVL E
Sbjct: 208 DLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEE 267

Query: 277 MREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQ 336
           MR QYEAM E NRRD EEWF+ +  ELN++V+T++  +Q  +++I +LRRT+  LEIELQ
Sbjct: 268 MRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQ 327

Query: 337 SQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKT 396
           +Q S++  LENT+ E+E RY+ QL Q+Q +I+++EAQL+E+R+++E QNQEY++LLD++ 
Sbjct: 328 AQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRA 387

Query: 397 RLEQEIATYRSLLEGQDAKMIGFPSSAGS 425
           RLE EI TYRSLLE +D K+   P S  S
Sbjct: 388 RLEGEINTYRSLLENEDCKLPCNPCSTPS 416


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  354 bits (908), Expect = 1e-97
 Identities = 183/337 (54%), Positives = 251/337 (74%), Gaps = 2/337 (0%)

Query: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCA-SYQS 105

Query: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
           Y+KTIEEL+ KIL +  EN R++++IDNA+LA+DDFR KYE EL+LRQ VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165

Query: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
           LDELTL ++DLE Q+ESL EEL  +K+NHE+E+     Q+  ++NVE+DA P +DL +VL
Sbjct: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225

Query: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 395 KTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRST 431
           + RLE EI TYRSLLE +D K+   P +  +   +ST
Sbjct: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACDKST 382


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  352 bits (902), Expect = 5e-97
 Identities = 182/326 (55%), Positives = 243/326 (74%), Gaps = 2/326 (0%)

Query: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQS 105

Query: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
           Y+KTIEEL+ KIL    EN R++++IDNA+LAADDFR KY+ EL+LRQ VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165

Query: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
           LDELTL K+DLE Q+ESL EEL  +K NHE+E+     Q+  ++NVE+DA P +DL RVL
Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225

Query: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 395 KTRLEQEIATYRSLLEGQDAKMIGFP 420
           + RLE EI TYRSLLE +D  +   P
Sbjct: 346 RARLECEINTYRSLLESEDCNLPSNP 371


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  347 bits (890), Expect = 1e-95
 Identities = 179/326 (54%), Positives = 244/326 (74%), Gaps = 2/326 (0%)

Query: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQS 105

Query: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
           Y+KTIEEL+ KIL +  EN R++++IDNA+LAADDFR KY+ E +LRQ VE+DIN LRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165

Query: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
           LDELTL ++DLE Q+ESL EEL  +K+NHE+E+     Q+  ++NVE+DA P +DL +VL
Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225

Query: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 395 KTRLEQEIATYRSLLEGQDAKMIGFP 420
           + RLE EI TYRSLLE +D K+   P
Sbjct: 346 RARLECEINTYRSLLESEDCKLPSNP 371


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  343 bits (880), Expect = 2e-94
 Identities = 180/343 (52%), Positives = 246/343 (71%), Gaps = 2/343 (0%)

Query: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  I++   +Q P      Y  
Sbjct: 90  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCP-SYQS 147

Query: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
           Y+KTIEEL+ KIL A  EN R+++ IDNA+LA+DDFR KY+ E +LR  VE+DIN +RR+
Sbjct: 148 YFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRI 207

Query: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
           LDELTL K+DLE Q+ESL EEL  +KKNHEEE+    +Q+  ++NVE+D  P +DL +VL
Sbjct: 208 LDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVL 267

Query: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 268 NETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIE 327

Query: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
           LQ+Q +++  LENT+ E+E  Y+ QL Q+Q LI+++E+QL+E+R ++E QNQEY++LLD+
Sbjct: 328 LQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDV 387

Query: 395 KTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTS 437
           + RLE EI TYRSLLE +D K+   P +  + S  S     TS
Sbjct: 388 RARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTS 430


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  323 bits (827), Expect = 3e-88
 Identities = 190/417 (45%), Positives = 270/417 (64%), Gaps = 25/417 (5%)

Query: 30  STCSTRFVSGGS--AGGYGG-------GVSCGFGGGAGSGFGGGYGGGLGGGYG-GGLGG 79
           ST ST + S GS  A  YG         V  G  GG+GS           GG G GGL  
Sbjct: 7   STFSTNYRSLGSVQAPSYGARPVSSAASVYAG-AGGSGSRISVSRSTSFRGGMGSGGLAT 65

Query: 80  GFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW 139
           G  GG AG         GG+   NEK TMQ+LNDRLASYL++VR+LE  N  LE KIR+ 
Sbjct: 66  GIAGGLAGM--------GGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREH 115

Query: 140 HLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199
             K+ P    RD+S Y+K IE+LR +I   T++N R++L+IDNARLAADDFR+KYE ELA
Sbjct: 116 LEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELA 173

Query: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQ-V 258
           +RQSVE DI+GLR+V+D+  +++  LE +IE+L EEL +MKKNHEEE+K    Q+    +
Sbjct: 174 MRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGL 233

Query: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
            VE+DA    DL +++A++R QY+ +A +NR + ++++  +  E    V+T +A +  ++
Sbjct: 234 TVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAE 293

Query: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
           T +TELRRT+Q LEI+L S  ++KA LEN++ E E RYALQ++Q+ G++  +E++L++ R
Sbjct: 294 TTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTR 353

Query: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLE-GQDAKMIGFPSSAGSVSPRSTSVT 434
           +E + Q QEY+ LL+IK +LE EIATYR LLE G+D  +     S+ S+     + T
Sbjct: 354 AEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  323 bits (827), Expect = 3e-88
 Identities = 190/417 (45%), Positives = 270/417 (64%), Gaps = 25/417 (5%)

Query: 30  STCSTRFVSGGS--AGGYGG-------GVSCGFGGGAGSGFGGGYGGGLGGGYG-GGLGG 79
           ST ST + S GS  A  YG         V  G  GG+GS           GG G GGL  
Sbjct: 7   STFSTNYRSLGSVQAPSYGARPVSSAASVYAG-AGGSGSRISVSRSTSFRGGMGSGGLAT 65

Query: 80  GFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW 139
           G  GG AG         GG+   NEK TMQ+LNDRLASYL++VR+LE  N  LE KIR+ 
Sbjct: 66  GIAGGLAGM--------GGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREH 115

Query: 140 HLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199
             K+ P    RD+S Y+K IE+LR +I   T++N R++L+IDNARLAADDFR+KYE ELA
Sbjct: 116 LEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELA 173

Query: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQ-V 258
           +RQSVE DI+GLR+V+D+  +++  LE +IE+L EEL +MKKNHEEE+K    Q+    +
Sbjct: 174 MRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGL 233

Query: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
            VE+DA    DL +++A++R QY+ +A +NR + ++++  +  E    V+T +A +  ++
Sbjct: 234 TVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAE 293

Query: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
           T +TELRRT+Q LEI+L S  ++KA LEN++ E E RYALQ++Q+ G++  +E++L++ R
Sbjct: 294 TTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTR 353

Query: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLE-GQDAKMIGFPSSAGSVSPRSTSVT 434
           +E + Q QEY+ LL+IK +LE EIATYR LLE G+D  +     S+ S+     + T
Sbjct: 354 AEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  322 bits (824), Expect = 6e-88
 Identities = 172/344 (50%), Positives = 241/344 (70%), Gaps = 9/344 (2%)

Query: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
           C+ G+ T NEK TMQ LNDRLASYLEKVR+LEE NA+LE +I++   +Q       DY  
Sbjct: 80  CEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQE-QCEQDIPMVCPDYQR 138

Query: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
           Y+ TIE+L+ KIL    EN+R+ +++DN +LA DDF+ KYE+EL+LRQ +EADI+ L  +
Sbjct: 139 YFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGI 198

Query: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
           L+ELTL K+DLE  +ESL E+L  +KKNHEEE+     Q+  +++VE+D  P +DL RVL
Sbjct: 199 LEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVL 258

Query: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
            EMR Q E +   NRR+AEEW   ++ ELN++  ++   +Q  + EI EL+RT   LEIE
Sbjct: 259 DEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIE 318

Query: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
           LQ+Q S+   LE TVAETE +Y+ QL QIQ LI ++E QL+E+R ++E QNQEY++LLD+
Sbjct: 319 LQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDV 378

Query: 395 KTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSS 438
           K RLE EI TY  LL+ +D+++        S SP ST+ T++++
Sbjct: 379 KARLEGEINTYWGLLDSEDSRL--------SCSPCSTTCTSSNT 414


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  318 bits (814), Expect = 8e-87
 Identities = 176/365 (48%), Positives = 243/365 (66%), Gaps = 3/365 (0%)

Query: 93  GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
           GA     L G+EK TMQ LNDRLA+YLEKVR LE+ NA+LE  + +     +S   P  D
Sbjct: 93  GAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCP--D 150

Query: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
           Y  Y+ TIEEL+ KIL +  EN R+I++IDNA+LAADDFR+K E+E +LRQ VEAD  G 
Sbjct: 151 YQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGT 210

Query: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
           +++LD+ TL+K DLE Q ESL EE   +K NHE+E+K   +Q+  ++ +E+D  P IDL 
Sbjct: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLN 270

Query: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
           RVL EMR QYEAM E NR+D E+WF A+S  ++ +  + +  +Q  ++EI ELR T+  L
Sbjct: 271 RVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNAL 330

Query: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
           E+E Q+Q ++K  L+N++ E E R+  +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 331 EVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVL 390

Query: 392 LDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRR 451
           LD+KTRLE EIATYR+LLE +D K+   P S       +      S    TT     G  
Sbjct: 391 LDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSCVTAPCAPRPSCGPCTTCGPTCGAS 450

Query: 452 TSDVR 456
           T+  R
Sbjct: 451 TTGSR 455


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  313 bits (801), Expect = 3e-85
 Identities = 170/362 (46%), Positives = 239/362 (66%), Gaps = 13/362 (3%)

Query: 100 LTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTI 159
           +  NEK TMQ LN+RLA+YL+KVR LE  NA+LE KI++   K+ P     DY  YY TI
Sbjct: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP-DYLSYYTTI 150

Query: 160 EELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELT 219
           EEL+ KIL    EN+R++ +IDN +L ADD R KYE E++LRQ VE+D NGL+++L+ LT
Sbjct: 151 EELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLT 210

Query: 220 LSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMRE 279
           L K DLE Q++SL EEL  +K NH+EE+     Q+  ++++E+ A P  DL +VL EMR 
Sbjct: 211 LGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRC 270

Query: 280 QYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQL 339
           QYE + E NR+D E+WF+ +  ELN++V T++   Q  + EI ELRR++  LE+ELQ+Q 
Sbjct: 271 QYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQH 330

Query: 340 SMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLE 399
            M+   E  + ETE RY   L QIQ LI ++EAQL+E+R  +E QNQEY++LLD+K+RLE
Sbjct: 331 RMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLE 390

Query: 400 QEIATYRSLLEGQDAKMIGFPSS------------AGSVSPRSTSVTTTSSASVTTTSNA 447
            EI TYRSLLE  D K   +P +            +G++   + + T++S  S+    +A
Sbjct: 391 CEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEHCSA 450

Query: 448 SG 449
            G
Sbjct: 451 CG 452


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  313 bits (801), Expect = 3e-85
 Identities = 174/362 (48%), Positives = 241/362 (66%), Gaps = 9/362 (2%)

Query: 93  GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
           GA     L G+EK TM+ LNDRLA+YLEKVR LE+ NA+LE  + +     +S   P  D
Sbjct: 93  GAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCP--D 150

Query: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
           Y  Y++TIEEL+ KIL +  EN R+I++IDNA+LAADDFR+K E+E +L Q VEAD  G 
Sbjct: 151 YQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGT 210

Query: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
           +++LD+ TL+K DLE Q ESL EE   +K NHE+E+K   +Q+  +  +E+D  P IDL 
Sbjct: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLN 270

Query: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
           RVL EMR QYEAM E N +D E+WF A+S  ++ +  + +  +Q  ++EI ELR T+  L
Sbjct: 271 RVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNAL 330

Query: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
           E+E Q+Q ++K  L+N++ E E RY  +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 331 EVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVL 390

Query: 392 LDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRR 451
           LD+K RLE EIATYR+LLE +D K+   P S         S T+  S    T  + SG  
Sbjct: 391 LDVKARLENEIATYRNLLESEDCKLPCNPCST------PASCTSCPSCGPVTGGSPSGHG 444

Query: 452 TS 453
            S
Sbjct: 445 AS 446


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  308 bits (790), Expect = 5e-84
 Identities = 175/402 (43%), Positives = 249/402 (61%), Gaps = 20/402 (4%)

Query: 60  GFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACD--GG---------LLTGNEKITM 108
           G GGG+G          + GG GG          +C   GG         LL GN K TM
Sbjct: 17  GAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATM 76

Query: 109 QNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILT 168
           QNLNDRLASYLEKVRALEEAN  LE +I  WH ++ P S ++DYS Y + I  L+++I+ 
Sbjct: 77  QNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGS-KKDYSQYEENITHLQEQIVD 135

Query: 169 ATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQ 228
             + N ++IL IDNAR+A DDF LKYENE + ++ +E ++ GLRR LD LT+  TDLE +
Sbjct: 136 GKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQE 195

Query: 229 IESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERN 288
           +E + +EL  MKK+HE+EM++        VNV++D  P  DL +VL +MR++YE + ++ 
Sbjct: 196 VEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKK 255

Query: 289 RRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENT 348
            RD + W+  +SA +++E + + A +Q+ + +I EL+RT Q LEI+LQ+Q S K+ LEN 
Sbjct: 256 HRDLDTWYKEQSAAMSQE-AASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENM 314

Query: 349 VAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSL 408
           ++ET+ RY+ +LQ +Q +IS  E +L++LR E+E QN EY++LL IKT LE+EI TYR L
Sbjct: 315 LSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRL 374

Query: 409 LEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGR 450
           LEG+              S  S  V+ T      T    +GR
Sbjct: 375 LEGES-------EGTREESKSSMKVSATPKIKAITQETINGR 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,590,420
Number of Sequences: 37866
Number of extensions: 812837
Number of successful extensions: 24905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 443
Number of HSP's successfully gapped in prelim test: 591
Number of HSP's that attempted gapping in prelim test: 7866
Number of HSP's gapped (non-prelim): 6715
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.