Guide to the Human Genome
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Name: MITF Sequence: fasta or formatted (419aa) NCBI GI: 4557755
Description:

microphthalmia-associated transcription factor isoform 4

Referenced in:

Skin and Related Tissues
Helix-Loop-Helix Transcription Factors

Other entries for this name:
alt prot [413aa] microphthalmia-associated transcription factor isoform 5
alt prot [520aa] microphthalmia-associated transcription factor isoform 1
alt prot [519aa] microphthalmia-associated transcription factor isoform 3
alt prot [504aa] microphthalmia-associated transcription factor isoform 2
alt prot [495aa] microphthalmia-associated transcription factor isoform 6
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         23           1
 C cysteine            2.4         10           1
 D aspartate           5.0         21           2
 E glutamate           7.4         31           2
 F phenylalanine       1.2          5           1
 G glycine             4.5         19           1
 H histidine           3.1         13           2
 I isoleucine          5.0         21           2
 K lysine              5.0         21           2
 L leucine            11.5         48           3
 M methionine          3.8         16           1
 N asparagine          7.4         31           3
 P proline             6.4         27           3
 Q glutamine           6.0         25           2
 R arginine            5.3         22           4
 S serine              8.1         34           2
 T threonine           6.7         28           3
 V valine              3.3         14           1
 W tryptophan          0.2          1           1
 Y tyrosine            2.1          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   microphthalmia-associated transcription factor isofor... 
MITF                  0.976   microphthalmia-associated transcription factor isofo...
MITF                  0.948   microphthalmia-associated transcription factor isofo...
MITF                  0.948   microphthalmia-associated transcription factor isofo...
MITF                  0.948   microphthalmia-associated transcription factor isofo...
MITF                  0.948   microphthalmia-associated transcription factor isofo...
TFE3                  0.414   transcription factor E3 
TFEB                  0.338   transcription factor EB 
TFEC                  0.308   transcription factor EC isoform a 
TFEC                  0.283   transcription factor EC isoform b 
USF2                  0.041   upstream stimulatory factor 2 isoform 2 
USF2                  0.041   upstream stimulatory factor 2 isoform 1 
USF1                  0.038   upstream stimulatory factor 1 isoform 1 
USF1                  0.038   upstream stimulatory factor 1 isoform 2 
SREBF1                0.034   sterol regulatory element binding transcription fact...
SREBF1                0.034   sterol regulatory element binding transcription fact...
SREBF2                0.033   sterol regulatory element-binding transcription fact...
KIAA2018              0.029   hypothetical protein LOC205717 
MYCN                  0.023   v-myc myelocytomatosis viral related oncogene, neuro...
CLOCK                 0.022   clock 
ARNTL2                0.021   aryl hydrocarbon receptor nuclear translocator-like ...
ARNT                  0.021   aryl hydrocarbon receptor nuclear translocator isofo...
ARNT                  0.021   aryl hydrocarbon receptor nuclear translocator isofor...
RNASEN                0.021   ribonuclease III, nuclear isoform 1 
ARNTL                 0.021   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.021   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.021   aryl hydrocarbon receptor nuclear translocator-like ...
MXD4                  0.021   MAD4 
ARNT                  0.018   aryl hydrocarbon receptor nuclear translocator isofo...
TFAP4                 0.018   transcription factor AP-4 (activating enhancer bindin...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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