Guide to the Human Genome
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Name: MITF Sequence: fasta or formatted (504aa) NCBI GI: 38156703
Description:

microphthalmia-associated transcription factor isoform 2

Referenced in:

Skin and Related Tissues
Helix-Loop-Helix Transcription Factors

Other entries for this name:
alt prot [413aa] microphthalmia-associated transcription factor isoform 5
alt prot [520aa] microphthalmia-associated transcription factor isoform 1
alt prot [519aa] microphthalmia-associated transcription factor isoform 3
alt prot [495aa] microphthalmia-associated transcription factor isoform 6
alt prot [419aa] microphthalmia-associated transcription factor isoform 4
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         29           2
 C cysteine            2.0         10           1
 D aspartate           4.2         21           2
 E glutamate           7.3         37           2
 F phenylalanine       1.4          7           1
 G glycine             4.0         20           1
 H histidine           2.6         13           2
 I isoleucine          4.6         23           2
 K lysine              4.8         24           2
 L leucine            10.9         55           3
 M methionine          4.4         22           1
 N asparagine          6.2         31           3
 P proline             6.9         35           3
 Q glutamine           7.7         39           3
 R arginine            5.8         29           4
 S serine              9.3         47           4
 T threonine           6.3         32           3
 V valine              4.2         21           1
 W tryptophan          0.2          1           1
 Y tyrosine            1.6          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   microphthalmia-associated transcription factor isofo... 
MITF                  0.961   microphthalmia-associated transcription factor isofo...
MITF                  0.961   microphthalmia-associated transcription factor isofo...
MITF                  0.961   microphthalmia-associated transcription factor isofo...
MITF                  0.802   microphthalmia-associated transcription factor isofo...
MITF                  0.796   microphthalmia-associated transcription factor isofor...
TFE3                  0.418   transcription factor E3 
TFEB                  0.339   transcription factor EB 
TFEC                  0.265   transcription factor EC isoform a 
TFEC                  0.245   transcription factor EC isoform b 
USF2                  0.035   upstream stimulatory factor 2 isoform 2 
USF2                  0.035   upstream stimulatory factor 2 isoform 1 
USF1                  0.032   upstream stimulatory factor 1 isoform 1 
USF1                  0.032   upstream stimulatory factor 1 isoform 2 
SREBF1                0.030   sterol regulatory element binding transcription fact...
SREBF1                0.030   sterol regulatory element binding transcription fact...
SREBF2                0.028   sterol regulatory element-binding transcription fact...
KIAA2018              0.028   hypothetical protein LOC205717 
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
ARNTL                 0.020   aryl hydrocarbon receptor nuclear translocator-like ...
WNK1                  0.019   WNK lysine deficient protein kinase 1 
CLOCK                 0.018   clock 
EP400                 0.018   E1A binding protein p400 
MXD4                  0.018   MAD4 
ARNTL2                0.017   aryl hydrocarbon receptor nuclear translocator-like ...
ARNT                  0.017   aryl hydrocarbon receptor nuclear translocator isofo...
ARNT                  0.017   aryl hydrocarbon receptor nuclear translocator isofor...
MYCN                  0.017   v-myc myelocytomatosis viral related oncogene, neuro...
RNASEN                0.017   ribonuclease III, nuclear isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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