Guide to the Human Genome
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Name: TFEB Sequence: fasta or formatted (476aa) NCBI GI: 24307933
Description:

transcription factor EB

Referenced in:

Helix-Loop-Helix Transcription Factors

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         31           2
 C cysteine            0.2          1           1
 D aspartate           4.8         23           2
 E glutamate           7.1         34           2
 F phenylalanine       1.7          8           1
 G glycine             5.5         26           2
 H histidine           3.2         15           2
 I isoleucine          2.9         14           1
 K lysine              4.0         19           2
 L leucine            11.1         53           2
 M methionine          4.4         21           1
 N asparagine          4.0         19           1
 P proline            10.5         50           3
 Q glutamine           8.2         39          10
 R arginine            5.9         28           4
 S serine             10.1         48           3
 T threonine           3.2         15           2
 V valine              4.4         21           2
 W tryptophan          0.4          2           1
 Y tyrosine            1.9          9           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transcription factor EB 
MITF                  0.357   microphthalmia-associated transcription factor isofo...
MITF                  0.357   microphthalmia-associated transcription factor isofo...
MITF                  0.357   microphthalmia-associated transcription factor isofo...
MITF                  0.357   microphthalmia-associated transcription factor isofo...
TFE3                  0.344   transcription factor E3 
MITF                  0.305   microphthalmia-associated transcription factor isofo...
MITF                  0.299   microphthalmia-associated transcription factor isofor...
TFEC                  0.242   transcription factor EC isoform a 
TFEC                  0.228   transcription factor EC isoform b 
USF2                  0.037   upstream stimulatory factor 2 isoform 2 
USF2                  0.037   upstream stimulatory factor 2 isoform 1 
MAML2                 0.030   mastermind-like 2 
SREBF2                0.028   sterol regulatory element-binding transcription fact...
MED12                 0.026   mediator complex subunit 12 
MNT                   0.025   MAX binding protein 
SREBF1                0.025   sterol regulatory element binding transcription fact...
SREBF1                0.025   sterol regulatory element binding transcription fact...
USF1                  0.025   upstream stimulatory factor 1 isoform 1 
USF1                  0.025   upstream stimulatory factor 1 isoform 2 
NCOA3                 0.024   nuclear receptor coactivator 3 isoform a 
NCOA3                 0.024   nuclear receptor coactivator 3 isoform b 
ATXN1                 0.024   ataxin 1 
ATXN1                 0.024   ataxin 1 
TOX3                  0.024   TOX high mobility group box family member 3 isoform...
TOX3                  0.024   TOX high mobility group box family member 3 isoform...
FOXP2                 0.023   forkhead box P2 isoform I 
FOXP2                 0.023   forkhead box P2 isoform III 
FOXP2                 0.023   forkhead box P2 isoform II 
MED15                 0.022   mediator complex subunit 15 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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