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Search of human proteins with 4557291
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 1122 0.0
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens] 550 e-156
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 86 1e-16
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 81 3e-15
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 79 8e-15
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 79 1e-14
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 79 1e-14
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 79 1e-14
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 77 5e-14
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 77 5e-14
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens] 76 9e-14
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 76 9e-14
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 75 1e-13
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 74 3e-13
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 71 3e-12
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 71 3e-12
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 69 8e-12
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 69 1e-11
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens] 68 2e-11
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens] 68 2e-11
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 66 7e-11
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 64 5e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ... 63 6e-10
gi|38788274 bromodomain PHD finger transcription factor isoform ... 63 6e-10
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 61 3e-09
gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens] 60 5e-09
gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens] 60 5e-09
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 58 2e-08
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 58 2e-08
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 58 2e-08
>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
Length = 545
Score = 1122 bits (2902), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MATDAALRRLLRLHRTEIAVAVDSAFPLLHALADHDVVPEDKFQETLHLKEKEGCPQAFH 60
MATDAALRRLLRLHRTEIAVAVDSAFPLLHALADHDVVPEDKFQETLHLKEKEGCPQAFH
Sbjct: 1 MATDAALRRLLRLHRTEIAVAVDSAFPLLHALADHDVVPEDKFQETLHLKEKEGCPQAFH 60
Query: 61 ALLSWLLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSFPKDVDLSQPRKGRKPPAVPK 120
ALLSWLLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSFPKDVDLSQPRKGRKPPAVPK
Sbjct: 61 ALLSWLLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSFPKDVDLSQPRKGRKPPAVPK 120
Query: 121 ALVPPPRLPTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSAEQQRLPLGNG 180
ALVPPPRLPTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSAEQQRLPLGNG
Sbjct: 121 ALVPPPRLPTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSAEQQRLPLGNG 180
Query: 181 IQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEFYTPSKFEDSG 240
IQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEFYTPSKFEDSG
Sbjct: 181 IQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEFYTPSKFEDSG 240
Query: 241 SGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQLHQKNEDECA 300
SGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQLHQKNEDECA
Sbjct: 241 SGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQLHQKNEDECA 300
Query: 301 VCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQEP 360
VCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQEP
Sbjct: 301 VCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQEP 360
Query: 361 PVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSALHPLLCV 420
PVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSALHPLLCV
Sbjct: 361 PVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSALHPLLCV 420
Query: 421 GPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVT 480
GPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVT
Sbjct: 421 GPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVT 480
Query: 481 PAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEHTFDGILQWAIQSMARPA 540
PAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEHTFDGILQWAIQSMARPA
Sbjct: 481 PAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEHTFDGILQWAIQSMARPA 540
Query: 541 APFPS 545
APFPS
Sbjct: 541 APFPS 545
>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
Length = 348
Score = 550 bits (1418), Expect = e-156
Identities = 269/322 (83%), Positives = 279/322 (86%), Gaps = 5/322 (1%)
Query: 227 GGEFYTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPG---GGEARLGQQGSVPAPL 283
GG + P + G G+ S G + + G Q G G E L ++ P+P+
Sbjct: 29 GGVCWRPDGWGTGGQGRISGPGSMGAGQRLGSSGTQRCCWGSCFGKEVAL-RRVLHPSPV 87
Query: 284 ALPSDPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQA 343
+ L QKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQA
Sbjct: 88 CMGVSC-LCQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQA 146
Query: 344 TVQEVQPRAEEPRPQEPPVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSA 403
TVQEVQPRAEEPRPQEPPVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSA
Sbjct: 147 TVQEVQPRAEEPRPQEPPVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSA 206
Query: 404 APLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGT 463
APLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGT
Sbjct: 207 APLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGT 266
Query: 464 SRPGTGLRCRSCSGDVTPAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEH 523
SRPGTGLRCRSCSGDVTPAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEH
Sbjct: 267 SRPGTGLRCRSCSGDVTPAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEH 326
Query: 524 TFDGILQWAIQSMARPAAPFPS 545
TFDGILQWAIQSMARPAAPFPS
Sbjct: 327 TFDGILQWAIQSMARPAAPFPS 348
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 85.5 bits (210), Expect = 1e-16
Identities = 43/100 (43%), Positives = 56/100 (56%), Gaps = 6/100 (6%)
Query: 293 QKNEDE----CAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEV 348
++ ED+ C VC+DGGEL+CCD CP ++HL CL+PPL EIP+G W C C ++
Sbjct: 409 EEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGK 468
Query: 349 QPRAEEPRPQEPPVETPLPPGLRSAGEEVRGPPGEPLAGM 388
R R EPP P GL E PP +PL G+
Sbjct: 469 VQRILHWRWTEPP--APFMVGLPGPDVEPSLPPPKPLEGI 506
Score = 73.6 bits (179), Expect = 4e-13
Identities = 64/233 (27%), Positives = 92/233 (39%), Gaps = 38/233 (16%)
Query: 134 ASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSAEQQRLPLGNGIQTMSASVQRAVA 193
+S A AAA AA T SP L PP+ P Q +P+ R
Sbjct: 204 SSAAAAAAAVAAAVETVTISP--PLAVSPPQVP------QPVPI------------RKAK 243
Query: 194 MSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEFYTPSKFEDSGSGKNKARSSSGPK 253
G PG R ++G G KK G+ KF G + + SS +
Sbjct: 244 TKEGKGPGVRKKIKG-------SKDGKKKG---KGKKTAGLKFRFGGISNKRKKGSSSEE 293
Query: 254 PLVRAKGAQGAAPGGGEAR------LGQQGSVPAPLALPSDPQLHQKN-EDECAVCRDGG 306
A+ R LG++ D ++ + +D C VC+ GG
Sbjct: 294 DEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQDYCEVCQQGG 353
Query: 307 ELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQE 359
E+I CD CPRA+HL CL P L + P G W C C + +Q +P+ ++ +E
Sbjct: 354 EIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQ-WEPKDDDDEEEE 405
Score = 34.7 bits (78), Expect = 0.23
Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGVL----- 488
C VC DG ++L C C +++H C P P C C+ V+ +L
Sbjct: 419 CRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQRILHWRWT 478
Query: 489 -APSPARLA-PGP 499
P+P + PGP
Sbjct: 479 EPPAPFMVGLPGP 491
Score = 30.0 bits (66), Expect = 5.7
Identities = 13/42 (30%), Positives = 17/42 (40%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC G +++ C C A+H C P P C C
Sbjct: 346 CEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHC 387
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 80.9 bits (198), Expect = 3e-15
Identities = 39/89 (43%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 299 CAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC----LQATVQEV------ 348
C VC+DGGEL+CCD CP ++H+ CL+PPL EIP+G W C C L+ VQ++
Sbjct: 452 CRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALKGKVQKILIWKWG 511
Query: 349 QPRAEEPRPQEPPVE--TPLPPGLRSAGE 375
QP + P P+ P + TP P L E
Sbjct: 512 QPPSPTPVPRPPDADPNTPSPKPLEGRPE 540
Score = 75.5 bits (184), Expect = 1e-13
Identities = 61/244 (25%), Positives = 91/244 (37%), Gaps = 66/244 (27%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEE 354
++D C VC+ GGE+I CD CPRA+H+ CL P + + P G W C C + + +Q A+E
Sbjct: 369 HQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK---EGIQWEAKE 425
Query: 355 PRPQEPPVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSAL 414
S GEE+ G L D H+
Sbjct: 426 D---------------NSEGEEILEEVGGDLEEEDD----HHMEF--------------- 451
Query: 415 HPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRS 474
C VC DG ++L C C +++H C P P C
Sbjct: 452 -------------------CRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPR 492
Query: 475 CSGDVTPAPVEGVL------APSPARL-APGPAKDDTASHEPALHRDDLESLLSEHTFDG 527
C+ V+ +L PSP + P A +T S +P R + + + + G
Sbjct: 493 CTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPLEGRPERQFFVK---WQG 549
Query: 528 ILQW 531
+ W
Sbjct: 550 MSYW 553
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 79.3 bits (194), Expect = 8e-15
Identities = 56/160 (35%), Positives = 74/160 (46%), Gaps = 34/160 (21%)
Query: 199 VPGARGAVEGILIQQVFESGGSKKCIQV-GGEFYTPSKFEDSGSGKNKARSSSGPKPLVR 257
+P G V+GIL ++ E G KCIQ G+++TP +FE G R
Sbjct: 303 LPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGG-------------YAR 349
Query: 258 AKGAQGAAPGGGEA--RLGQQGSVPAPLAL---------------PSDPQLHQKNEDECA 300
+K + + GG RL ++GS+P P + DP + +N DEC
Sbjct: 350 SKNWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCM--RNLDECE 407
Query: 301 VCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 340
VCRDGGEL CCD C R FH C PP+ E W C C
Sbjct: 408 VCRDGGELFCCDTCSRVFHEDCHIPPV-ESEKTPWNCIFC 446
Score = 34.3 bits (77), Expect = 0.30
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSR--PGTGLRCR 473
C VC DG ++ C C+ FH CH P S P + CR
Sbjct: 406 CEVCRDGGELFCCDTCSRVFHEDCHIPPVESEKTPWNCIFCR 447
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 79.0 bits (193), Expect = 1e-14
Identities = 37/89 (41%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 299 CAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQ 358
C VC+DGGEL+CCD C ++H+ CL+PPL +IP+G W C C ++ + R
Sbjct: 459 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 518
Query: 359 EPPVETPLPPGLRSAGEEVRGPPGEPLAG 387
EPPV P P + A PP PL G
Sbjct: 519 EPPVAVPAP---QQADGNPDVPPPRPLQG 544
Score = 76.3 bits (186), Expect = 7e-14
Identities = 65/249 (26%), Positives = 94/249 (37%), Gaps = 47/249 (18%)
Query: 116 PAVPKALVPPPRL-----PTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSA 170
P+ P AL PPP P +R ++E + PG + ++K P+ P+
Sbjct: 236 PSGPPALPPPPAADIQPPPIRRAKTKEGKG-------------PGHKRRSKSPRVPD--- 279
Query: 171 EQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEF 230
G + + + + G + G R + Q G E
Sbjct: 280 ---------GRKKLRGKKMAPLKIKLGLLGGKRKKGGSYVFQS-----------DEGPEP 319
Query: 231 YTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQ 290
DSGS + + GP VR K + PG + ++ PA
Sbjct: 320 EAEESDLDSGSVHSASGRPDGP---VRTKKLKRGRPGRKKKKVL---GCPAVAGEEEVDG 373
Query: 291 LHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQP 350
++D C VC+ GGE+I CD CPRA+HL CL P L P G W C C + VQ
Sbjct: 374 YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAK 433
Query: 351 RAEEPRPQE 359
EE +E
Sbjct: 434 EEEEEYEEE 442
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGVLA---P 490
C VC DG ++L C C +++H C P P C C+ V V+ +L
Sbjct: 459 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 518
Query: 491 SPARLAPGPAKDD 503
P P P + D
Sbjct: 519 EPPVAVPAPQQAD 531
Score = 29.6 bits (65), Expect = 7.4
Identities = 13/42 (30%), Positives = 17/42 (40%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC G +++ C C A+H C P P C C
Sbjct: 382 CEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 79.0 bits (193), Expect = 1e-14
Identities = 37/89 (41%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 299 CAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQ 358
C VC+DGGEL+CCD C ++H+ CL+PPL +IP+G W C C ++ + R
Sbjct: 459 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 518
Query: 359 EPPVETPLPPGLRSAGEEVRGPPGEPLAG 387
EPPV P P + A PP PL G
Sbjct: 519 EPPVAVPAP---QQADGNPDVPPPRPLQG 544
Score = 76.3 bits (186), Expect = 7e-14
Identities = 65/249 (26%), Positives = 94/249 (37%), Gaps = 47/249 (18%)
Query: 116 PAVPKALVPPPRL-----PTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSA 170
P+ P AL PPP P +R ++E + PG + ++K P+ P+
Sbjct: 236 PSGPPALPPPPAADIQPPPIRRAKTKEGKG-------------PGHKRRSKSPRVPD--- 279
Query: 171 EQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEF 230
G + + + + G + G R + Q G E
Sbjct: 280 ---------GRKKLRGKKMAPLKIKLGLLGGKRKKGGSYVFQS-----------DEGPEP 319
Query: 231 YTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQ 290
DSGS + + GP VR K + PG + ++ PA
Sbjct: 320 EAEESDLDSGSVHSASGRPDGP---VRTKKLKRGRPGRKKKKVL---GCPAVAGEEEVDG 373
Query: 291 LHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQP 350
++D C VC+ GGE+I CD CPRA+HL CL P L P G W C C + VQ
Sbjct: 374 YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAK 433
Query: 351 RAEEPRPQE 359
EE +E
Sbjct: 434 EEEEEYEEE 442
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGVLA---P 490
C VC DG ++L C C +++H C P P C C+ V V+ +L
Sbjct: 459 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 518
Query: 491 SPARLAPGPAKDD 503
P P P + D
Sbjct: 519 EPPVAVPAPQQAD 531
Score = 29.6 bits (65), Expect = 7.4
Identities = 13/42 (30%), Positives = 17/42 (40%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC G +++ C C A+H C P P C C
Sbjct: 382 CEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 423
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 79.0 bits (193), Expect = 1e-14
Identities = 37/89 (41%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 299 CAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQ 358
C VC+DGGEL+CCD C ++H+ CL+PPL +IP+G W C C ++ + R
Sbjct: 518 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 577
Query: 359 EPPVETPLPPGLRSAGEEVRGPPGEPLAG 387
EPPV P P + A PP PL G
Sbjct: 578 EPPVAVPAP---QQADGNPDVPPPRPLQG 603
Score = 76.3 bits (186), Expect = 7e-14
Identities = 65/249 (26%), Positives = 94/249 (37%), Gaps = 47/249 (18%)
Query: 116 PAVPKALVPPPRL-----PTKRKASEEARAAAPAALTPRGTASPGSQLKAKPPKKPESSA 170
P+ P AL PPP P +R ++E + PG + ++K P+ P+
Sbjct: 295 PSGPPALPPPPAADIQPPPIRRAKTKEGKG-------------PGHKRRSKSPRVPD--- 338
Query: 171 EQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGEF 230
G + + + + G + G R + Q G E
Sbjct: 339 ---------GRKKLRGKKMAPLKIKLGLLGGKRKKGGSYVFQS-----------DEGPEP 378
Query: 231 YTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQ 290
DSGS + + GP VR K + PG + ++ PA
Sbjct: 379 EAEESDLDSGSVHSASGRPDGP---VRTKKLKRGRPGRKKKKVL---GCPAVAGEEEVDG 432
Query: 291 LHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQP 350
++D C VC+ GGE+I CD CPRA+HL CL P L P G W C C + VQ
Sbjct: 433 YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAK 492
Query: 351 RAEEPRPQE 359
EE +E
Sbjct: 493 EEEEEYEEE 501
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGVLA---P 490
C VC DG ++L C C +++H C P P C C+ V V+ +L
Sbjct: 518 CRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWG 577
Query: 491 SPARLAPGPAKDD 503
P P P + D
Sbjct: 578 EPPVAVPAPQQAD 590
Score = 29.6 bits (65), Expect = 7.4
Identities = 13/42 (30%), Positives = 17/42 (40%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC G +++ C C A+H C P P C C
Sbjct: 441 CEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHC 482
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 76.6 bits (187), Expect = 5e-14
Identities = 41/120 (34%), Positives = 62/120 (51%), Gaps = 8/120 (6%)
Query: 244 NKARSSSGPKPLVR--AKGAQGAAPGGGEARLGQ------QGSVPAPLALPSDPQLHQKN 295
N ++SS+ + ++R A + G PG + S +PL + + N
Sbjct: 766 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPN 825
Query: 296 EDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEP 355
ED CAVC++GGEL+CC+ CP+ FHL+C P L PSG W C+ C + EV+ + P
Sbjct: 826 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 885
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 409 LDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGT 468
LD S PL VG +++ C VC +G ++L C C FH CH P T+ P
Sbjct: 805 LDPSQKSPLH-VGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 863
Query: 469 GLRCRSCSGDVTPAPVE 485
C C D++ VE
Sbjct: 864 EWICTFCR-DLSKPEVE 879
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 76.6 bits (187), Expect = 5e-14
Identities = 41/120 (34%), Positives = 62/120 (51%), Gaps = 8/120 (6%)
Query: 244 NKARSSSGPKPLVR--AKGAQGAAPGGGEARLGQ------QGSVPAPLALPSDPQLHQKN 295
N ++SS+ + ++R A + G PG + S +PL + + N
Sbjct: 732 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPN 791
Query: 296 EDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEP 355
ED CAVC++GGEL+CC+ CP+ FHL+C P L PSG W C+ C + EV+ + P
Sbjct: 792 EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAP 851
Score = 39.7 bits (91), Expect = 0.007
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 409 LDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGT 468
LD S PL VG +++ C VC +G ++L C C FH CH P T+ P
Sbjct: 771 LDPSQKSPLH-VGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 829
Query: 469 GLRCRSCSGDVTPAPVE 485
C C D++ VE
Sbjct: 830 EWICTFCR-DLSKPEVE 845
>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
Length = 689
Score = 75.9 bits (185), Expect = 9e-14
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 30/183 (16%)
Query: 159 KAKPPKKPESSAEQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESG 218
++K KK + + I V +P G +GIL ++ + G
Sbjct: 424 RSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHG 483
Query: 219 GSKKCIQ-VGGEFYTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQG 277
S KCI+ G + TP++FE G G+N + K +R +G LG+
Sbjct: 484 SSVKCIRNEDGTWLTPNEFEVEGKGRN----AKNWKRNIRCEGMT----------LGEL- 528
Query: 278 SVPAPLALPSDPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRC 337
L +KN DEC VC GG+L+CC CPR FH C PP+ E W C
Sbjct: 529 -------------LKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSC 574
Query: 338 SSC 340
+ C
Sbjct: 575 TFC 577
Score = 30.8 bits (68), Expect = 3.3
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
C VC G +L C C FH CH P
Sbjct: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIP 563
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 75.9 bits (185), Expect = 9e-14
Identities = 53/183 (28%), Positives = 76/183 (41%), Gaps = 30/183 (16%)
Query: 159 KAKPPKKPESSAEQQRLPLGNGIQTMSASVQRAVAMSSGDVPGARGAVEGILIQQVFESG 218
++K KK + + I V +P G +GIL ++ + G
Sbjct: 424 RSKEKKKEKDICSSSKRRFQKNIHRRGKPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHG 483
Query: 219 GSKKCIQ-VGGEFYTPSKFEDSGSGKNKARSSSGPKPLVRAKGAQGAAPGGGEARLGQQG 277
S KCI+ G + TP++FE G G+N + K +R +G LG+
Sbjct: 484 SSVKCIRNEDGTWLTPNEFEVEGKGRN----AKNWKRNIRCEGMT----------LGEL- 528
Query: 278 SVPAPLALPSDPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRC 337
L +KN DEC VC GG+L+CC CPR FH C PP+ E W C
Sbjct: 529 -------------LKRKNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPV-EAKRMLWSC 574
Query: 338 SSC 340
+ C
Sbjct: 575 TFC 577
Score = 30.8 bits (68), Expect = 3.3
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
C VC G +L C C FH CH P
Sbjct: 537 CEVCCQGGQLLCCGTCPRVFHEDCHIP 563
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 75.5 bits (184), Expect = 1e-13
Identities = 36/92 (39%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Query: 279 VPAPLALPSDPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCS 338
+P P +NED CAVC +GGEL+CCD CP+ FHL+C P L P G W C+
Sbjct: 953 IPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCT 1012
Query: 339 SCLQATVQEVQPRAEEPRPQEPPVETPLPPGL 370
C T E++ E +P + PGL
Sbjct: 1013 LCRSLTQPEMEYDCENACYNQPGMRA--SPGL 1042
Score = 41.6 bits (96), Expect = 0.002
Identities = 19/48 (39%), Positives = 22/48 (45%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTP 481
C VC +G ++L C C FH CH PA S PG C C P
Sbjct: 973 CAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQP 1020
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 73.9 bits (180), Expect = 3e-13
Identities = 56/151 (37%), Positives = 73/151 (48%), Gaps = 16/151 (10%)
Query: 199 VPGARGAVEGILIQQVFESGGSKKCIQV-GGEFYTPSKFEDSGSGKNKARSSS------- 250
+P G V+GIL ++ + G KCIQ G+++TP++FE G ARS +
Sbjct: 590 LPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGG---HARSKNWRLSVRC 646
Query: 251 GPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPS-DPQLHQKNEDECAVCRDGGELI 309
G PL R G P R ++ + S DP + +N DEC VCRDGGEL
Sbjct: 647 GGWPL-RWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPCM--RNLDECEVCRDGGELF 703
Query: 310 CCDGCPRAFHLACLSPPLREIPSGTWRCSSC 340
CCD C R FH C PP+ E W C C
Sbjct: 704 CCDTCSRVFHEDCHIPPV-EAERTPWNCIFC 733
Score = 33.9 bits (76), Expect = 0.39
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
C VC DG ++ C C+ FH CH P
Sbjct: 693 CEVCRDGGELFCCDTCSRVFHEDCHIP 719
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query: 9 RLLRLHRTEIAVAVDSAFPLLHALADHDVVPE---DKFQETLHLKEKEGCPQAFHALLSW 65
R R ++ EIA A+ FP L L D + E + FQE + + + +LS
Sbjct: 44 RFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEA--FRNLVPVTRVMYCVLSE 101
Query: 66 LLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSF 100
L + T LF NL Y L I SF
Sbjct: 102 L---EKTFGWSHLEALFSRINLMAYPDLNEIYRSF 133
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 70.9 bits (172), Expect = 3e-12
Identities = 28/55 (50%), Positives = 36/55 (65%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQ 349
NED CAVC++GG+L+CC+ CP+ FHL C P L PSG W C+ C EV+
Sbjct: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVE 940
Score = 39.7 bits (91), Expect = 0.007
Identities = 17/42 (40%), Positives = 19/42 (45%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC +G D+L C C FH CH P S P C C
Sbjct: 890 CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC 931
Score = 33.5 bits (75), Expect = 0.51
Identities = 55/201 (27%), Positives = 74/201 (36%), Gaps = 40/201 (19%)
Query: 267 GGGEARLGQQGSVPAPL--------ALPSDPQL-----HQKNEDECAVCRDGGELICCDG 313
GGGEA G GS AP+ A ++P L ++ E+ +GG DG
Sbjct: 6 GGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDG 65
Query: 314 CPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQEPPVETPLPPGLRSA 373
A SG+ + +S A+V P P P P
Sbjct: 66 GVAA------------ASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAP------ 107
Query: 374 GEEVRGPPGEPLAGMDTTLV-YKHLPAPPSAAP--LPGLDSSALHPLLCVGPEGQQNLAP 430
G PPG P + +DT V + L + A P LP L S L L PE ++ L+
Sbjct: 108 GPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL----PEPERQLSV 163
Query: 431 GARCGVCGD--GTDVLRCTHC 449
G GD V+RC C
Sbjct: 164 PIPGGSNGDIQQVGVIRCPVC 184
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 70.9 bits (172), Expect = 3e-12
Identities = 28/55 (50%), Positives = 36/55 (65%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQ 349
NED CAVC++GG+L+CC+ CP+ FHL C P L PSG W C+ C EV+
Sbjct: 886 NEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVE 940
Score = 39.7 bits (91), Expect = 0.007
Identities = 17/42 (40%), Positives = 19/42 (45%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSC 475
C VC +G D+L C C FH CH P S P C C
Sbjct: 890 CAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC 931
Score = 33.5 bits (75), Expect = 0.51
Identities = 55/201 (27%), Positives = 74/201 (36%), Gaps = 40/201 (19%)
Query: 267 GGGEARLGQQGSVPAPL--------ALPSDPQL-----HQKNEDECAVCRDGGELICCDG 313
GGGEA G GS AP+ A ++P L ++ E+ +GG DG
Sbjct: 6 GGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDG 65
Query: 314 CPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRPQEPPVETPLPPGLRSA 373
A SG+ + +S A+V P P P P
Sbjct: 66 GVAA------------ASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAP------ 107
Query: 374 GEEVRGPPGEPLAGMDTTLV-YKHLPAPPSAAP--LPGLDSSALHPLLCVGPEGQQNLAP 430
G PPG P + +DT V + L + A P LP L S L L PE ++ L+
Sbjct: 108 GPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCL----PEPERQLSV 163
Query: 431 GARCGVCGD--GTDVLRCTHC 449
G GD V+RC C
Sbjct: 164 PIPGGSNGDIQQVGVIRCPVC 184
>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
Length = 680
Score = 69.3 bits (168), Expect = 8e-12
Identities = 31/63 (49%), Positives = 39/63 (61%), Gaps = 7/63 (11%)
Query: 282 PLALPS----DPQLHQKNEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRC 337
P++LPS D +H ED C+VCR G+L+ CD C R +HL CL PPL+ IP G W C
Sbjct: 473 PVSLPSPTSTDGDIH---EDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWIC 529
Query: 338 SSC 340
C
Sbjct: 530 PRC 532
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/169 (28%), Positives = 74/169 (43%), Gaps = 15/169 (8%)
Query: 192 VAMSSGDVPGARGAVEGILIQQVFESGGSKKCIQVGGE-FYTPSKFE---DSGSGKN--- 244
+ ++P G V+G L ++ F+ G SKKCIQ + ++TP +FE D G+ KN
Sbjct: 598 INFKQSELPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKL 657
Query: 245 KARSSSGPKPLVRAKGAQGAAPGGGEARLGQQGSVPAPLALPSDPQLHQKNEDECAVCRD 304
R ++ P + R+ + + P +N + C VC
Sbjct: 658 SIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTLVDPCP-------ENSNICEVCNK 710
Query: 305 GGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAE 353
G L CCD CPR+FH C P + E W C C T+QE P ++
Sbjct: 711 WGRLFCCDTCPRSFHEHCHIPSV-EANKNPWSCIFCRIKTIQERCPESQ 758
Score = 32.3 bits (72), Expect = 1.1
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 14 HRTEIAVAVDSAFPLLHALADHDVVPEDKFQETLHLKEKEGCPQAF---HALLSWLLTQD 70
++ EI+ A+ FP L L D D++ F+++ ++ C + + L +
Sbjct: 60 NKVEISNAIKKTFPFLEGLRDRDLITNKMFEDS-----QDSCRNLVPVQRVVYNVLSELE 114
Query: 71 STAILDFWRVLFKDYNLERYGRLQPILDSF 100
T L LF D N++ Y L I F
Sbjct: 115 KTFNLPVLEALFSDVNMQEYPDLIHIYKGF 144
Score = 32.0 bits (71), Expect = 1.5
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 9/81 (11%)
Query: 395 KHLPAPPSAAPLPGLDSSALHPLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFH 454
K LP PPS L+S H V P + + C VC + C C +FH
Sbjct: 673 KFLPEPPSTRKKRILES---HNNTLVDPCPENSNI----CEVCNKWGRLFCCDTCPRSFH 725
Query: 455 WRCHFPA--GTSRPGTGLRCR 473
CH P+ P + + CR
Sbjct: 726 EHCHIPSVEANKNPWSCIFCR 746
>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
Length = 1004
Score = 68.2 bits (165), Expect = 2e-11
Identities = 26/48 (54%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLRE--IPSGTWRCSSC 340
N D C C++GG+L+CCD CP AFHL C +PPL E +P G W C C
Sbjct: 55 NHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRC 102
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/38 (47%), Positives = 23/38 (60%)
Query: 308 LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATV 345
LI CD CP FH+ CL PPL +P G W C + ++ V
Sbjct: 286 LIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVV 323
Score = 36.2 bits (82), Expect = 0.079
Identities = 14/27 (51%), Positives = 17/27 (62%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
C C +G D+L C HC AAFH +C P
Sbjct: 59 CDSCKEGGDLLCCDHCPAAFHLQCCNP 85
>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
Length = 704
Score = 68.2 bits (165), Expect = 2e-11
Identities = 26/48 (54%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLRE--IPSGTWRCSSC 340
N D C C++GG+L+CCD CP AFHL C +PPL E +P G W C C
Sbjct: 55 NHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRC 102
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/38 (47%), Positives = 23/38 (60%)
Query: 308 LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATV 345
LI CD CP FH+ CL PPL +P G W C + ++ V
Sbjct: 286 LIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVV 323
Score = 36.2 bits (82), Expect = 0.079
Identities = 14/27 (51%), Positives = 17/27 (62%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFP 460
C C +G D+L C HC AAFH +C P
Sbjct: 59 CDSCKEGGDLLCCDHCPAAFHLQCCNP 85
>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
Length = 634
Score = 66.2 bits (160), Expect = 7e-11
Identities = 25/46 (54%), Positives = 31/46 (67%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 340
+ED C+VCR G+L+ CD C R +HL CL PPL+ IP G W C C
Sbjct: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC 486
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 63.5 bits (153), Expect = 5e-10
Identities = 56/246 (22%), Positives = 90/246 (36%), Gaps = 62/246 (25%)
Query: 274 GQQGSVPAPLALPSDPQLHQKNED------------ECAVCRDGGE---LICCDGCPRAF 318
GQ+ ++PA L P + + +K C +C+ + L+ CD C +
Sbjct: 691 GQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHY 750
Query: 319 HLACLSPPLREIPSGT----WRCSSCLQATVQEVQPRAEEPRPQEPPVETPLPPGLRSAG 374
HL CL PPL +P T W+CS C QA +++ + +ET LP G + +
Sbjct: 751 HLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDME--------ADMAMET-LPDGTKRSR 801
Query: 375 EEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSALHPLLCVGPEGQQNLAPGAR- 433
+++ P V + +P P P+ + E + P R
Sbjct: 802 RQIKEP---------VKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEEEKHEERVPRERR 852
Query: 434 ------------------CGVC---GDGTDVLRCTHCAAAFHWRCHFPAGTSRP---GTG 469
C C GD +++RC C +H+ C P P G G
Sbjct: 853 QRQSVLQKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYG 912
Query: 470 LRCRSC 475
C+ C
Sbjct: 913 WICQEC 918
Score = 49.3 bits (116), Expect = 9e-06
Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 9/73 (12%)
Query: 290 QLHQKNED---ECAVCRDGGE---LICCDGCPRAFHLACLSPPLREIPSGT---WRCSSC 340
Q K ED ECA C+ G+ L+ CD C +H CL PPL++ P T W C C
Sbjct: 859 QKKPKAEDLRTECATCKGTGDNENLVRCDECRLCYHFGCLDPPLKKSPKQTGYGWICQEC 918
Query: 341 LQATVQEVQPRAE 353
++ +E + AE
Sbjct: 919 DSSSSKEDENEAE 931
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 63.2 bits (152), Expect = 6e-10
Identities = 24/65 (36%), Positives = 35/65 (53%)
Query: 296 EDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEP 355
+D C VC G+L+CC+ C +HL C+ PPL E+P W+C C+ V V E
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449
Query: 356 RPQEP 360
+ +P
Sbjct: 450 QKNKP 454
Score = 31.2 bits (69), Expect = 2.5
Identities = 16/54 (29%), Positives = 21/54 (38%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGV 487
C VC D+L C C+A +H C P P +C C P + V
Sbjct: 393 CRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCV 446
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 63.2 bits (152), Expect = 6e-10
Identities = 24/65 (36%), Positives = 35/65 (53%)
Query: 296 EDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEP 355
+D C VC G+L+CC+ C +HL C+ PPL E+P W+C C+ V V E
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449
Query: 356 RPQEP 360
+ +P
Sbjct: 450 QKNKP 454
Score = 31.2 bits (69), Expect = 2.5
Identities = 16/54 (29%), Positives = 21/54 (38%)
Query: 434 CGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCRSCSGDVTPAPVEGV 487
C VC D+L C C+A +H C P P +C C P + V
Sbjct: 393 CRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCV 446
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 60.8 bits (146), Expect = 3e-09
Identities = 27/51 (52%), Positives = 32/51 (62%), Gaps = 3/51 (5%)
Query: 299 CAVCRDGGE---LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQ 346
C VCR GE LI CD C +AFHL CL P L E+P G W+C +C AT +
Sbjct: 1187 CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATAR 1237
>gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]
Length = 489
Score = 60.1 bits (144), Expect = 5e-09
Identities = 22/53 (41%), Positives = 32/53 (60%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQE 347
+++ CA C+ G L C CP A+HL+CL PPL+ P G W C C Q +++
Sbjct: 309 HDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 361
>gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]
Length = 531
Score = 60.1 bits (144), Expect = 5e-09
Identities = 22/53 (41%), Positives = 32/53 (60%)
Query: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQE 347
+++ CA C+ G L C CP A+HL+CL PPL+ P G W C C Q +++
Sbjct: 351 HDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKK 403
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 299 CAVCRDGGE---LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQA 343
C +C G E L+ CDGC +H+ CL PPL EIP G WRC C+ A
Sbjct: 260 CRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMA 307
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 58.2 bits (139), Expect = 2e-08
Identities = 24/48 (50%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 299 CAVCRDGGE---LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQA 343
C +C G E L+ CDGC +H+ CL PPL EIP G WRC C+ A
Sbjct: 327 CRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMA 374
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 58.2 bits (139), Expect = 2e-08
Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 299 CAVCRDGGE---LICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQE 347
C VC G E L+ CDGC +H+ CL PPL EIP G WRC C+ A ++
Sbjct: 260 CQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQ 311
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,640,881
Number of Sequences: 37866
Number of extensions: 1823524
Number of successful extensions: 14195
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 11315
Number of HSP's gapped (non-prelim): 3482
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.