Guide to the Human Genome
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Search of human proteins with 45387951

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45387951 transmembrane protein 108 [Homo sapiens]
         (575 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45387951 transmembrane protein 108 [Homo sapiens]                 1165   0.0  
gi|210147493 transmembrane protein 108 [Homo sapiens]                1165   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                          95   2e-19
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              91   2e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni...    87   4e-17
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        79   1e-14
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   3e-13
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    74   3e-13
gi|91982772 mucin 17 [Homo sapiens]                                    74   3e-13
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    74   4e-13
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       74   5e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    72   1e-12
gi|161019170 mucin 5AC [Homo sapiens]                                  71   2e-12
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                71   3e-12
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                71   3e-12
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                71   3e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   70   4e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   70   4e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   70   4e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    70   4e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    70   5e-12
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    70   7e-12
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    69   9e-12
gi|54860079 nadrin isoform 1 [Homo sapiens]                            67   6e-11
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                65   1e-10
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             65   2e-10
gi|167736355 mucin 4 isoform a [Homo sapiens]                          65   2e-10
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             64   3e-10
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             64   5e-10
gi|55750053 atrophin-1 [Homo sapiens]                                  64   5e-10

>gi|45387951 transmembrane protein 108 [Homo sapiens]
          Length = 575

 Score = 1165 bits (3015), Expect = 0.0
 Identities = 575/575 (100%), Positives = 575/575 (100%)

Query: 1   MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH 60
           MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH
Sbjct: 1   MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH 60

Query: 61  TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA 120
           TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA
Sbjct: 61  TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA 120

Query: 121 AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
           AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS
Sbjct: 121 AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180

Query: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
           RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP
Sbjct: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
           LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA
Sbjct: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300

Query: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
           TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT
Sbjct: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360

Query: 361 PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
           PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST
Sbjct: 361 PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420

Query: 421 VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI 480
           VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI
Sbjct: 421 VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI 480

Query: 481 SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE 540
           SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE
Sbjct: 481 SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE 540

Query: 541 PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 575
           PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI
Sbjct: 541 PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 575


>gi|210147493 transmembrane protein 108 [Homo sapiens]
          Length = 575

 Score = 1165 bits (3015), Expect = 0.0
 Identities = 575/575 (100%), Positives = 575/575 (100%)

Query: 1   MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH 60
           MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH
Sbjct: 1   MKRSLQALYCQLLSFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRH 60

Query: 61  TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA 120
           TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA
Sbjct: 61  TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA 120

Query: 121 AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
           AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS
Sbjct: 121 AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180

Query: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
           RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP
Sbjct: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
           LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA
Sbjct: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300

Query: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
           TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT
Sbjct: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360

Query: 361 PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
           PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST
Sbjct: 361 PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420

Query: 421 VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI 480
           VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI
Sbjct: 421 VVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPI 480

Query: 481 SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE 540
           SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE
Sbjct: 481 SSCSVLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSE 540

Query: 541 PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 575
           PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI
Sbjct: 541 PRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI 575


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 108/410 (26%), Positives = 150/410 (36%), Gaps = 73/410 (17%)

Query: 29   IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRA 88
            I  PSP  +    PS  P  T    P ++    +    TP P   PS       TP P  
Sbjct: 1396 ITTPSPPTTT---PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 89   EGHPPTHTISTIAATVT---APHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTK 145
               PP  T +T   T T      + S  +T P+P    TT+  P   P   + PT     
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP---SPPTTTPIT 1509

Query: 146  PPGATSR--PTT--APPRTTTRRP-----PRPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
            PP +T+   PTT  +PP TTT  P     P PP ++      S+  +PP           
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT---------- 1559

Query: 197  QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAAT 256
                 PS  P     P                   P T TP  P    +++P P T+  T
Sbjct: 1560 ---TTPSPPPTTTTTP-------------------PPTTTPSPPT---TTTPSPPTITTT 1594

Query: 257  TVPSNTSWAP--TTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAP 314
            T P  T+ +P  TTT+  P    P           T T+   T   T     P +    P
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT---TLPPTTTPSPPPTTTTTP 1651

Query: 315  VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
             P+  P        PS   +  T  P T+ P   SS + T  + PT     T+++ PS  
Sbjct: 1652 PPTTTP-SPPTTTTPSPPITTTTTPPPTTTP---SSPITTTPSPPT-----TTMTTPS-- 1700

Query: 375  IPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVST 424
                 +TTP +P   +    ST + +   T  T       PSP +T ++T
Sbjct: 1701 ----PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 1976 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2034

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 2035 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2328

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 2329 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2356

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 2357 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2650

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 2651 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2710

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 2711 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2678

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 2679 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2972

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 2973 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3032

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 3033 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 2942 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 3001 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3294

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 3295 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 3264 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3322

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 3323 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 116/459 (25%), Positives = 160/459 (34%), Gaps = 62/459 (13%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3644

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 3645 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA---SGAP 307
                  T    T+   TTT++ P     G +       +T T+   TP  T     +  P
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878

Query: 308  VSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTP---GTSRPLSTSSGVFTAAT-GPTPA 362
            ++      P+  P     P   P  + + +T TP   GT  P +T     T  T  PTP 
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3938

Query: 363  AFDTSVSAP----SQGIPQGASTTPQAPTHPSRVSESTI------SGAKEETVATLTMTD 412
               T  + P    +   P    T  Q PT     + +T+      +G +  T   +T T 
Sbjct: 3939 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3998

Query: 413  RV---PSPLSTVVSTATGNFLNRLV-----PAGTWKPGT 443
             V   P+P  T   T T       V     P GT  P T
Sbjct: 3999 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4037



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 111/435 (25%), Positives = 152/435 (34%), Gaps = 62/435 (14%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-------PTPRAEGHP 92
            V P+ TP GT        T  T+V   TP P G  +    P+ T       PTP     P
Sbjct: 3908 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3966

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILL 143
             T  I+T   TVT   + +   T        TT+  P   P G   P         T+  
Sbjct: 3967 TTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4025

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAPGGHSRSK-- 194
            T  P  T  PTT P  TTT   P P       P ++      +  P P   G  + +   
Sbjct: 4026 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085

Query: 195  -EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS---TLTPRTPLWGYSSSPQP 250
                    P+ TP G + P            T +V P P+   T TP T     +++  P
Sbjct: 4086 ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA-SGAPVS 309
                  T    T+   TTT++ P     G +       +T T+   TP  T   +G P  
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH 4200

Query: 310  PQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVS 369
               AP+      +  P+            TP TSR  S+     T      P A + + +
Sbjct: 4201 TSTAPIAELTTSNPPPESS----------TPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250

Query: 370  APSQGIPQGASTTPQAPTHP------SRVSESTISGAKEETVATLTMTDRVPSPLSTVVS 423
            AP         +TP APT        S    +T S     T  T T +   P+P STV +
Sbjct: 4251 AP--------PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP-STVQT 4301

Query: 424  TATGNFLNRLVPAGT 438
            T T  +     P  T
Sbjct: 4302 TTTSAWTPTPTPLST 4316



 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 120/486 (24%), Positives = 177/486 (36%), Gaps = 77/486 (15%)

Query: 29   IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRA 88
            I  P+   +L    + +PP T  T P  +T  +     TP+P  P +    P  T TP +
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP--PITTTTTPPPTTTPSS 1683

Query: 89   E----GHPPTHTISTIAATVTAPHSESSLSTGPA----PAAMATTSSKPEGRPRGQAAPT 140
                   PPT T++T + T T P S  + +T P+    P+   TT + P          T
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTT-PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742

Query: 141  ILLTKPPGATSRPTT-------------APPRTTTRRPPRPPGSSRKGAGNSSRPVPPAP 187
             + T PP  TS P T             +P  TTT   P  P  +  G  +S +P    P
Sbjct: 1743 TMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKP 1802

Query: 188  GGHSR-----------SKEGQRGRNPSSTPLGQKRPLGK--IFQIYKGNFTGSVEPEPST 234
            GG +            +    R       P+GQ   LG+  +  +  G    + + +P  
Sbjct: 1803 GGDTELIGDVCGPGWAANISCRATMYPDVPIGQ---LGQTVVCDVSVGLICKNEDQKPGG 1859

Query: 235  LTPRTPLWGYSSS-------PQPQTVAATT----VPSNTSWAPTTTSLGPAKDKPGLRRA 283
            + P      Y  +        QP T+  TT     P  T+   TTT++ P     G +  
Sbjct: 1860 VIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP 1919

Query: 284  AQGGGSTFTSQGGTPDATAA---SGAPVSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVT 339
                 +T T+   TP  T     +  P++      P+  P     P   P  + + +T T
Sbjct: 1920 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1979

Query: 340  P---GTSRPLSTSSGVFTAAT-GPTPAAFDTSVSAP----SQGIPQGASTTPQAPTHPSR 391
            P   GT  P +T     T  T  PTP    T  + P    +   P    T  Q PT    
Sbjct: 1980 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2039

Query: 392  VSESTI------SGAKEETVATLTMTDRV---PSPLSTVVSTATGNFLNRLV-----PAG 437
             + +T+      +G +  T   +T T  V   P+P  T   T T       V     P G
Sbjct: 2040 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2099

Query: 438  TWKPGT 443
            T  P T
Sbjct: 2100 TQTPTT 2105



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 92/343 (26%), Positives = 128/343 (37%), Gaps = 53/343 (15%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-----PTPRAEG-HPP 93
            V P+ TP GT        T  T+V   TP P G  +    P+ T     PTP   G   P
Sbjct: 4023 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4081

Query: 94   THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPT---------ILLT 144
            T T  T   TVT   + +   T        TT+  P   P G   PT         +  T
Sbjct: 4082 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4141

Query: 145  KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNS----SRPVPPAPGGHSRSKEGQRGR 200
              P  T  PTT P  TTT   P P  +  +    +    +  V P P     +  G +  
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTG 4196

Query: 201  NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
             P+ T      P+ ++        + + +   ST +P T      S+  P     +T P 
Sbjct: 4197 PPTHTSTA---PIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 4253

Query: 261  NTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRP 320
            +T  APTTTS G     P          ST TS  GTP     +G+  +P  + V +   
Sbjct: 4254 STPTAPTTTSGGHTLSPP---------PSTTTSPPGTPTRGTTTGSSSAPTPSTVQT--- 4301

Query: 321  HHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAA 363
                     + + +W   TP T  PLST S + T    P P++
Sbjct: 4302 ---------TTTSAW---TP-TPTPLSTPSIIRTTGLRPYPSS 4331



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 73/257 (28%), Positives = 104/257 (40%), Gaps = 42/257 (16%)

Query: 29   IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP-- 86
            I  P+   +L    + +PP T  T P  +T  +     TP+P    +    P  TP+P  
Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606

Query: 87   -RAEGHPPTHTISTIAAT-VTAPHSESSL--STGPAPAAMATTSSKPEGRPRGQAAPTIL 142
                  PPT T S    T +T P S ++L  +T P+P    TT+  P   P   + PT  
Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTT 1663

Query: 143  LTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP 202
               PP  T   TT PP TTT   P            ++ P PP                 
Sbjct: 1664 TPSPPITT---TTTPPPTTTPSSP-----------ITTTPSPPT--------------TT 1695

Query: 203  SSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNT 262
             +TP     P   I      + T +  P P+T+T  +P    +++P P T   TT+P  T
Sbjct: 1696 MTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP----TTTPSPPTTTMTTLPPTT 1751

Query: 263  SWAP-TTTSLGPAKDKP 278
            + +P TTT L P+   P
Sbjct: 1752 TSSPLTTTPLPPSITPP 1768



 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 90/363 (24%), Positives = 123/363 (33%), Gaps = 65/363 (17%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPT---PRAEGHPPTHTIS 98
            P  T P    T P   T  T+    T  P  P +    P A+ T   P     PPT T +
Sbjct: 1472 PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTT 1531

Query: 99   TIAAT----------VTAPHSESSL--STGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            T   T          +T P S ++L  +T P+P    TT+  P   P   + PT     P
Sbjct: 1532 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSP 1588

Query: 147  PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP 206
            P  T   TT PP TTT   P PP ++      ++ P PP                P + P
Sbjct: 1589 PTIT---TTTPPPTTT---PSPPTTTTTTPPPTTTPSPPT-------------TTPITPP 1629

Query: 207  LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAP 266
                                +  P P   T  TP    + SP   T  +  + + T+  P
Sbjct: 1630 TSTT------------TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 267  TTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQ 326
            TTT   P    P          S  T+       T    +  +P   P     P    P 
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP---SPT 1734

Query: 327  DGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAP 386
              PS   + +T  P    P +TSS +    T P P +      +P       ++TTP  P
Sbjct: 1735 TTPSPPTTTMTTLP----PTTTSSPL---TTTPLPPSITPPTFSPF------STTTPTTP 1781

Query: 387  THP 389
              P
Sbjct: 1782 CVP 1784



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 98/394 (24%), Positives = 137/394 (34%), Gaps = 68/394 (17%)

Query: 80   PMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP 139
            P  TP+P     PPT T +T+  T T           P+P    TT+  P   P    +P
Sbjct: 1402 PTTTPSP-----PPTST-TTLPPTTT-----------PSPPTTTTTTPPPTTTP----SP 1440

Query: 140  TILLTKPPGATSRPTTAPPRTTTRRPP---RPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
             I  T  P  T+ P+  PP +TT  PP    P   +   +  ++ P PP     +     
Sbjct: 1441 PITTTTTPPPTTTPS--PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTT-TTTTPPPT 1497

Query: 197  QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAAT 256
                 P++TP+        +          +  P P T T  TP    +++P P T    
Sbjct: 1498 TTPSPPTTTPITPPASTTTL--------PPTTTPSPPTTTTTTP--PPTTTPSPPTTTPI 1547

Query: 257  TVPSNT---------SWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAP 307
            T P++T         S  PTTT+  P    P           T T+   TP  T     P
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT--TPPPTTTPSPP 1605

Query: 308  VSPQAAPVPSQRPHHG--------------DPQDGPSHSDSWLTVTPGTSRP----LSTS 349
             +    P P+  P                  P   PS   +  T  P T+ P     +T 
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665

Query: 350  SGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLT 409
            S   T  T P P    +S    +   P    TTP   T PS    +T + +   T +   
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725

Query: 410  MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGT 443
             T   PSP +T     T   +  L P  T  P T
Sbjct: 1726 TTMTTPSPTTTPSPPTT--TMTTLPPTTTSSPLT 1757



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 87/351 (24%), Positives = 123/351 (35%), Gaps = 50/351 (14%)

Query: 104  VTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATS-----RPTTAPP 158
            +T P   S  +T P+P   +TT+  P   P   + PT   T PP  T+       TT PP
Sbjct: 1396 ITTP---SPPTTTPSPPPTSTTTLPPTTTP---SPPTTTTTTPPPTTTPSPPITTTTTPP 1449

Query: 159  RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
             TTT   P PP S+      ++ P PP       +         ++TP            
Sbjct: 1450 PTTT---PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP------------ 1494

Query: 219  IYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQ------PQTVAATTVPSNTSWAPTTTSLG 272
                    +  P P T TP TP    ++ P       P T   T  P+ T   PTTT + 
Sbjct: 1495 ------PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1548

Query: 273  PAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHS 332
            P      L           T+    P  T +     +P    + +  P    P   PS  
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPP 1605

Query: 333  DSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRV 392
             +  T  P T+ P   S    T  T PT        + PS   P   +TTP   T PS  
Sbjct: 1606 TTTTTTPPPTTTP---SPPTTTPITPPTSTTTLPPTTTPSP--PPTTTTTPPPTTTPSPP 1660

Query: 393  SESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGT 443
            + +T S      + T T      +P S + +T +        P+ T  P +
Sbjct: 1661 TTTTPS----PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 81/303 (26%), Positives = 110/303 (36%), Gaps = 70/303 (23%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT-----PTPRAEG-HPP 93
            V P+ TP GT        T  T+V   TP P G  +    P+ T     PTP   G   P
Sbjct: 4115 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4173

Query: 94   THTISTIAATVTAPHSESSLSTGP------APAAMATTSSKPEGRPRGQAA--------- 138
            T T  T   TVT   + +   TGP      AP A  TTS+ P      Q +         
Sbjct: 4174 TTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233

Query: 139  PTILLTKPPGATSRPTTAPPRTTTR----------RPP-----RPPGSSRKGA--GNSSR 181
             T LL+  P A    +TAPP T T            PP      PPG+  +G   G+SS 
Sbjct: 4234 STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293

Query: 182  PVPPAPGGHSRSKEGQRGRNPSSTPLGQK--------RPLGKIF---------------Q 218
            P P      + S        P+ TPL           RP                    +
Sbjct: 4294 PTPSTVQTTTTS-----AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEE 4348

Query: 219  IYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP 278
            +Y G +  +      +L+     + +S    P T + T  PS ++  P+  S  P+K  P
Sbjct: 4349 VYNGTYGDTCYFVNCSLSCTLEFYNWSC---PSTPSPTPTPSKSTPTPSKPSSTPSKPTP 4405

Query: 279  GLR 281
            G +
Sbjct: 4406 GTK 4408


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 137/559 (24%), Positives = 193/559 (34%), Gaps = 100/559 (17%)

Query: 40   VLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPM-----ATPTPRAEG-HPP 93
            V P+ TP GT        T  T+V   TP P G  +    P+      TPTP   G   P
Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1403

Query: 94   THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---------TILLT 144
            T T  T   TVT   + +   T        TT+  P   P G  AP         T+  T
Sbjct: 1404 TSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPT 1463

Query: 145  KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
              P  T  PTT P  TTT   P P  +       +  P P A    +          P+ 
Sbjct: 1464 PTPTGTQTPTTTPITTTTTVTPTPTPT------GTQTPTPTAITTTTTV-------TPTP 1510

Query: 205  TPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS---- 260
            TP G + P            T +V P P+    +TP      +P P +   T  P+    
Sbjct: 1511 TPTGTQTPTSTPI-----TTTTTVTPTPTPTGTQTP------TPTPISTTTTVTPTPTPT 1559

Query: 261  -----NTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP----- 310
                  T+   TTT++ P     G +       +T T+   TP  T+     V+P     
Sbjct: 1560 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTT 1619

Query: 311  --QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSV 368
               A P P+     G          +  TVTP T  P + S+G  T  +    A   TS 
Sbjct: 1620 TVTATPTPT-----GTQTPTMIPISTTTTVTP-TPTPTTGSTGPPTHTSTAPIAELTTSN 1673

Query: 369  SAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
              P    PQ + +T  +P   S    ST+  A E       MT   P    T  +T +G 
Sbjct: 1674 PPPESSTPQTSRST-SSPLTESTTLLSTLPPAIE-------MTSTAPPSTPTAPTTTSGG 1725

Query: 429  FLNRLVPAGTWKP---GTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISVPISSCSV 485
                  P+ T  P    T G  +  +    P    T   S    AW       P+S+ S+
Sbjct: 1726 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS----AWT--PTPTPLSTPSI 1779

Query: 486  LLT-----------VCCMKRKKKTANPE-------NNLSYWNN---TITMDYFNRHAVEL 524
            + T           +CC+      A  E        +  Y+ N   + T++++N      
Sbjct: 1780 IRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST 1839

Query: 525  PREIQSLETSEDQLSEPRS 543
            P    +   S    S+P S
Sbjct: 1840 PSPTPTPSKSTPTPSKPSS 1858



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 102/375 (27%), Positives = 138/375 (36%), Gaps = 71/375 (18%)

Query: 30   QEPSPRE---SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMA---- 82
            Q P+P     +  V P+ TP GT      ++T  T+   +TP P    +Q   P A    
Sbjct: 1447 QAPTPTAITTTSTVTPTPTPTGTQTP---TTTPITTTTTVTPTPTPTGTQTPTPTAITTT 1503

Query: 83   ---TPTPRAEG-HPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSS-KPEGRPRGQA 137
               TPTP   G   PT T  T   TVT   + +   T P P  ++TT++  P   P G  
Sbjct: 1504 TTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQT-PTPTPISTTTTVTPTPTPTGTQ 1562

Query: 138  AP---------TILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKG------AGNSSRP 182
             P         T+  T  P  T  PTT    TTT   P P  +S K          ++  
Sbjct: 1563 TPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVT 1622

Query: 183  VPPAPGGHSRSKEGQRGRNPSSTP-----LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTP 237
              P P G             + TP      G   P            T S  P P + TP
Sbjct: 1623 ATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTS-NPPPESSTP 1681

Query: 238  RTPLWGYSSSPQPQTVAAT---------TVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGG 288
            +T     S   +  T+ +T         T P +T  APTTTS G     P          
Sbjct: 1682 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP---------P 1732

Query: 289  STFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST 348
            ST TS  GTP     +G+  +P  + V +            + + +W   TP T  PLST
Sbjct: 1733 STTTSPPGTPTRGTTTGSSSAPTPSTVQT------------TTTSAW---TP-TPTPLST 1776

Query: 349  SSGVFTAATGPTPAA 363
             S + T    P P++
Sbjct: 1777 PSIIRTTGLRPYPSS 1791



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 99/397 (24%), Positives = 142/397 (35%), Gaps = 59/397 (14%)

Query: 80   PMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP 139
            P    T   E   PT   +T   T T P   S+ ST P P    TT+  P   P G   P
Sbjct: 1300 PTTMTTTTTENPTPTPITTTTTVTPT-PTPTSTQSTTPTPIT-TTTTVTPTPTPTGTQTP 1357

Query: 140  ---------TILLTKPPGATSRPTTAPPRTTTRRPPRP-------PGSSRKGAGNSSRPV 183
                     T+  T  P  T  PTT P  TTT   P P       P S+      +  P 
Sbjct: 1358 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPT 1417

Query: 184  PPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWG 243
            P   G           + P++TP+     +           TG+  P P+ +T  + +  
Sbjct: 1418 PTPTG----------TQTPTTTPITTTTTVTP-----TPTPTGTQAPTPTAITTTSTV-- 1460

Query: 244  YSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA 303
               +P P T   T  P+ T    TTT++ P     G +       +T T+   TP  T  
Sbjct: 1461 ---TPTP-TPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGT 1515

Query: 304  ---SGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTP-----GTSRPLSTSSGVFTA 355
               +  P++      P+  P  G     P+   +  TVTP     GT  P +T     T 
Sbjct: 1516 QTPTSTPITTTTTVTPTPTP-TGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTP---ITT 1571

Query: 356  ATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDR-V 414
             T  TP    T    P+  +    +T    PT P+    +T++     T  T T T    
Sbjct: 1572 TTTVTPTPTPTGTQTPTTVLITTTTTMTPTPT-PTSTKSTTVTPITTTTTVTATPTPTGT 1630

Query: 415  PSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVA 451
             +P    +ST T      + P  T   G+ G  +H +
Sbjct: 1631 QTPTMIPISTTT-----TVTPTPTPTTGSTGPPTHTS 1662



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 99/385 (25%), Positives = 137/385 (35%), Gaps = 72/385 (18%)

Query: 30   QEPSPRE---SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
            Q P+P     +  V P+ TP GT        T  T+V   TP P G  +     + T T 
Sbjct: 1539 QTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTVLITTTTT 1597

Query: 87   RAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRP---RGQAAPTILL 143
                  PT T ST   TVT   + ++++  P P    T +  P            PT   
Sbjct: 1598 MTPTPTPTSTKST---TVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGS 1654

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----------VPPAPGGHSRS 193
            T PP  TS   TAP    T   P P  S+ + + ++S P          +PPA    S +
Sbjct: 1655 TGPPTHTS---TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 1711

Query: 194  KEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP----LWGYSSSPQ 249
                    P STP               G  T S  P  +T  P TP      G SS+P 
Sbjct: 1712 --------PPSTPTAPTTT--------SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT 1755

Query: 250  PQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVS 309
            P TV  TT    ++W PT T L                 S   + G  P  ++     V 
Sbjct: 1756 PSTVQTTT---TSAWTPTPTPLSTP--------------SIIRTTGLRPYPSSVLICCVL 1798

Query: 310  PQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVS 369
                  P +  ++G      ++ D+   V    S  L   +    +   PTP     S S
Sbjct: 1799 NDTYYAPGEEVYNG------TYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---PSKS 1849

Query: 370  APSQGIPQGASTTPQAPTHPSRVSE 394
             P+   P   S+TP  PT  ++  E
Sbjct: 1850 TPT---PSKPSSTPSKPTPGTKPPE 1871



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 57/228 (25%), Positives = 86/228 (37%), Gaps = 37/228 (16%)

Query: 231  EPSTLTPRTPLWGYSSSPQPQTVAATT------VPSNT-SWAP----TTTSLGPAKDKPG 279
            +P+T+T  T     + +P P  +  TT       P++T S  P    TTT++ P     G
Sbjct: 1299 QPTTMTTTT-----TENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTG 1353

Query: 280  LRRAAQGGGSTFTSQGGTPDATAA---SGAPVSPQAAPVPSQRPHHGD-PQDGPSHSDSW 335
             +       +T T+   TP  T     +  P++      P+  P     P   P  + + 
Sbjct: 1354 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413

Query: 336  LTVTP---GTSRPLSTSSGVFTAAT---------GPTPAAFDTSVSAPSQGIPQGASTTP 383
            +T TP   GT  P +T     T  T          PTP A  T+ +      P G  T  
Sbjct: 1414 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPT 1473

Query: 384  QAP--THPSRVSESTISGAKEETVATLTMTDRV---PSPLSTVVSTAT 426
              P  T  +     T +G +  T   +T T  V   P+P  T   T+T
Sbjct: 1474 TTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTST 1521


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 121/454 (26%), Positives = 169/454 (37%), Gaps = 72/454 (15%)

Query: 28   AIQEPSPRESLQVLP----SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT 83
            A+  PSP+ S    P    + TPP     +P  S         TP P G P+  AA + +
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA------ATPLPKGAPTTPAATLPS 1066

Query: 84   P-----TPRAEGHPPTHTISTIAATVTAPHS-ESSLSTGPAPAAMATTSSKPEG---RPR 134
            P     TP  +G P     +  AAT  +P    ++ S   AP   A T   P+G    P 
Sbjct: 1067 PKGGPATPSLKGAP-----TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121

Query: 135  GQAAPTILLTKPP----GATSRPTTAPPRTTTRRPPRPPGS----SRKGAGNSSRPVPPA 186
             + APT     PP    G  + P    P T    PP P G       KGA  +    PP+
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 187  P-GGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEP----STLTPR-TP 240
            P GG +          P++TP   K  L             +  P P    +T +P+  P
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 241  LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGS-----TFTSQG 295
                ++ P P+   AT  P     APT  +  P   K GL      G       T  S  
Sbjct: 1242 TTPAATPPSPKGGPATPPPKG---APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK 1298

Query: 296  GTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR-----PLSTSS 350
            G P  +   GAP  P A P PS +   G P   P  + +   VTP + +     P +T S
Sbjct: 1299 GGPATSPPKGAPTPPAATP-PSPKGSPGTPP--PKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 351  GVFTAAT-----GPTPAAFDTS--------VSAPSQG----IPQGASTTPQA-PTHPSRV 392
                  T     GPTP A   S          +P +G     P+G  T+P   P  P + 
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 393  SESTISGAKEETVATLTMTDRVPSPLSTVVSTAT 426
              + ++     T +   +T    +P+S   + AT
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 116/411 (28%), Positives = 150/411 (36%), Gaps = 83/411 (20%)

Query: 32   PSPRESLQV-LPSGTPPGTMVTAPHSSTRHTSV---VMLTPNPDGPPSQAAAPM------ 81
            P P+E      P   P  +M ++     R T     +  +P+P G P+  AA        
Sbjct: 894  PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 82   -ATPTPRAEGHPPTHTISTIAATVTAPHS-ESSLSTGPAPAAMATTSSKPEG---RPRGQ 136
             ATP+P+    PP       AAT  +P    ++ S   AP   A T   P+G    P  +
Sbjct: 954  PATPSPKWAPTPP-------AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006

Query: 137  AAPTILLTKPPGATSRPTTAP-PRTTT----RRPPRPPGSSR-----KGAGNSSRPVPPA 186
             APT     PP     P   P P+  +      PP P GS       KGA  +     P+
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 187  P-GGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYS 245
            P GG +          P++TP   K   G      KG       P P   TP +P  G +
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKG--GPATPSPKG------APMPPAATPPSPKGGLA 1118

Query: 246  SSPQ--PQTVAATTVPS--------NTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQG 295
            + P     T  A T PS            APTT +  P   K GL      G  T     
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT----- 1173

Query: 296  GTPDATAAS-----------GAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTP---- 340
             TP AT  S           GAP +P A P PS  P  G     P  + +    TP    
Sbjct: 1174 -TPAATPPSPKGGLATPSPKGAPTTPAATP-PS--PKGGLATPSPKGAPTTPAATPPSPK 1229

Query: 341  -GTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPS 390
             G + P    +    AAT P+P         P+   P+GA  TP A T PS
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPK------GGPATPPPKGA-PTPPAATPPS 1273



 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 119/453 (26%), Positives = 157/453 (34%), Gaps = 105/453 (23%)

Query: 25   LAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNP----DGPPSQAAAP 80
            L  A + P    S  + P+GTPPGT      S T   + V  +P      D   S  A+ 
Sbjct: 724  LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783

Query: 81   MATPTPRAEG-------------HPPTHTIS----TIAATVTAPHS--------ESSLST 115
              T T  A+               PPT   S    T    +++P S        E+SLS 
Sbjct: 784  KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 116  GPAPAAMATTSSKPEGRPRGQAAPTIL-------LTKPP-----------------GATS 151
              +  + ATT S     P+G   P+ +       +T PP                  AT 
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 152  RPTTAPPRTTTRRPPR-----------PPGSSRKGAGNSSRPVPPAP-GGHSRSKEGQRG 199
             P  AP  + T   P+           P   S KGA       PP+P GG +        
Sbjct: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 200  RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSS-----SPQPQTV- 253
              P++TP   K   G      KG       P P   TP +P  G ++     +P P  V 
Sbjct: 964  TPPAATPPSPKG--GPATPSPKG------APTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015

Query: 254  --------AATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGG----GSTFTSQGGTPDAT 301
                    AAT  P   S  P  T   P K  P      +G      +T  S  G P   
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSP-KGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 302  AASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTP 361
            +  GAP  P A P PS       P+ GP+         P  + P S   G+ T      P
Sbjct: 1075 SLKGAPTPPAATP-PS-------PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 362  AAFDTSVSAPSQGI----PQGASTTPQAPTHPS 390
                 +  +P  G+    P+GA TTP A T PS
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTP-AATPPS 1158



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 94/405 (23%), Positives = 141/405 (34%), Gaps = 96/405 (23%)

Query: 37   SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPN-PDGPPSQAAAPMATP--TPRAEGHPP 93
            +L ++P+ +    +  +P ++    + ++L P  P   PS +  P  TP  T + +G   
Sbjct: 697  TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756

Query: 94   THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRP 153
            T  ++ +A++     +E S        A AT SSK           T L   P      P
Sbjct: 757  TSALAPVASSPKECPTEDS-------GASATASSK--------GTLTYLADSPS-----P 796

Query: 154  TTAPPRTTTRRPPRPPGSSRKGA--GNSSRPVPPAPGG----HSRSKEGQRGRNPSSTPL 207
                    T+RPP   GS+      GN S PV P        +S S +G +    ++   
Sbjct: 797  LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856

Query: 208  GQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPT 267
                P G               P PS +TP +P                T+P   +  P+
Sbjct: 857  TPPSPKGA--------------PTPSAVTPLSP-------------KGVTLPPKETPTPS 889

Query: 268  TTSLGPAKDKPGLRRAAQGGGSTFTSQG-----------GTPDATAASGAPVSPQAAPVP 316
              +L   K+ P      Q    + TS             G P + +  GAP  P A P P
Sbjct: 890  VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-P 948

Query: 317  SQRPHHGDPQDGPSH-SDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGI 375
            S       P+ GP+  S  W    P              AAT P+P         P+   
Sbjct: 949  S-------PKGGPATPSPKWAPTPP--------------AATPPSPKG------GPATPS 981

Query: 376  PQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
            P+GA T P A     +   +T S     T   +T      SP +T
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 106/408 (25%), Positives = 141/408 (34%), Gaps = 75/408 (18%)

Query: 37   SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHT 96
            SL+  P+ + P      P S    T   +  P+P  PP+      ++   +A   P    
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 97   ISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPT-ILLTKPPGATSRPTT 155
              T+ A + +   E            AT SS+     R   APT  LL+K   AT  P  
Sbjct: 1502 APTLPAVIPSSPKE----------VPATPSSR-----RDPIAPTATLLSKKTPATLAPKE 1546

Query: 156  A--PPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQK-RP 212
            A  PP  T   P + P          + P P        SKE      P+ TP   K  P
Sbjct: 1547 ALIPPAMTVPSPKKTP----------AIPTPKEAPATPSSKEA--SSPPAVTPSTYKGAP 1594

Query: 213  LGKIFQIYKGNFTGSVE--PEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTS 270
              K   I     + S +  P P  +TP          P P+   AT  P  T  +P  T 
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTP----------PSPEKGPATPAPKGTPTSPPVTP 1644

Query: 271  LGPAKDKPGLRRAAQGGGSTFTSQGGT-PDATAASGAPVSPQA------APVPSQRPHHG 323
                KD P          S     G T P A+    A   P A      AP P   P   
Sbjct: 1645 -SSLKDSP------TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697

Query: 324  DP-QDGPSHSDSWLT---VTPGTSRPLSTSSGVFTAATGP-TPAAFDTSVSAPSQGIPQG 378
             P + GP    S  T   + P  S    +   + T A  P  P   D+S +A      + 
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG----KD 1753

Query: 379  ASTTPQAPTHPSRVSEST-ISGAKEETVATLTMTDRVPSPLSTVVSTA 425
            AS +P+ P  P     ST ++ A  E V        +P P S  VS A
Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKV--------LPKPESASVSAA 1793



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 62/253 (24%), Positives = 94/253 (37%), Gaps = 51/253 (20%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH 91
            PSP+E L       PP   VT+P      T   +  P+P+  P       ATP P+    
Sbjct: 1594 PSPKELL------IPPA--VTSPSPKEAPTPPAVTPPSPEKGP-------ATPAPKGTPT 1638

Query: 92   PPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATS 151
             P  T S++  + T+P S +       P A     +K     +G  A   +L  P   ++
Sbjct: 1639 SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK-----KGPTALKEVLVAPAPEST 1693

Query: 152  RPTTAPPR--------TTTRRPPRPPGSSRKGAGNSSRPVPPAP--GGHSRSKEGQRGRN 201
               TAP R        + T  P  P  S++ G+      V PAP       S +  +G++
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753

Query: 202  PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSN 261
             S +P G   P                 PE    TP T        P+P++ + +  PS 
Sbjct: 1754 ASHSPKGPLAP-----------------PESKASTPLTAAAFEKVLPKPESASVSAAPS- 1795

Query: 262  TSWAPTTTSLGPA 274
                P +  L P+
Sbjct: 1796 ---PPVSLPLAPS 1805



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 112/481 (23%), Positives = 170/481 (35%), Gaps = 86/481 (17%)

Query: 26  AFAIQEPSPRESLQVLPSGT--PPGTMVTAPHSSTRHTSVVMLTPNPDGP---------- 73
           AF +  PS  +    + S T  P G++  A   S   T+ ++L  +P+            
Sbjct: 373 AFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMP 432

Query: 74  -PSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLS----TGPAPAAMATTSSK 128
             S    P+    P      PT T   +A  V+ P S   +S    T PA   MA  + K
Sbjct: 433 VSSVGTTPLVVTNPCTIAAAPTTTFE-VATCVSPPMSSGPISNIEPTSPAALVMAPVAPK 491

Query: 129 PEGRPRGQAAPTIL------LTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP 182
               P  Q A T+       L  P    + P++   +  T++  +   +S +GA     P
Sbjct: 492 ---EPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA-----P 543

Query: 183 VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGK-IFQIYKGNFTGSVEPEPSTLTPRT-- 239
             PA  G +  K+      P+  PL Q  P     FQ    +    + PE +TL  ++  
Sbjct: 544 FSPAQAGLTTKKD------PTVLPLVQAAPKNSPSFQSTSSSPEIPLSPE-ATLAKKSLG 596

Query: 240 -PLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLR-------------RAAQ 285
            PL      P     +   V S+ S   T +  GP    P L+              +A 
Sbjct: 597 EPL--PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654

Query: 286 GGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG--------PSHSDSWLT 337
             G   T+  GT   T  +    SP      S  P +   ++G        P+ S++   
Sbjct: 655 PAGVAPTTAKGTSTYTTTA----SPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN--- 707

Query: 338 VTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQG----------ASTTPQAPT 387
             P    P +T + + T    P       S S P  G P G          ++  P A +
Sbjct: 708 -CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASS 766

Query: 388 HPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNI 447
                +E + + A   +  TLT     PSPL   VS  T     +   AG   P   GN+
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP--IGNL 824

Query: 448 S 448
           S
Sbjct: 825 S 825



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 95/417 (22%), Positives = 144/417 (34%), Gaps = 58/417 (13%)

Query: 34  PRESLQVLPSGT-----PPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRA 88
           P E+ + +P+       P       P SS    +  +  P P  PP  + AP   P   A
Sbjct: 2   PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 89  EGHPPTHTISTIAAT---VTAPHSESS----LSTGP--------------APAAMATTSS 127
               P  + STIA+T   V  P S S     L T P              +PAA+A  S 
Sbjct: 62  NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121

Query: 128 KPEGRPRG---QAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVP 184
                 +G    +AP  L+   P +  + +  PP   T  P      S      S+   P
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181

Query: 185 PAPGGHSRSKEGQRGRNPSSTP----LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
             P  +      +   NP  TP    +    P   +  +   +    V   P T TP T 
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPM--ASIQSGVASLPQT-TPTTT 238

Query: 241 LWGYSSSPQPQTVAATTV-PSNTSWAPTTTSL-GPAKDKPGLRRAAQGGGSTFTSQGGTP 298
           L   S   +  T+++  + P N    P + SL GP      L  + Q      TS   T 
Sbjct: 239 LAIASPQVKDTTISSVLISPQN----PGSLSLKGPVSPPAALSLSTQ-SLPVVTSSQKTA 293

Query: 299 DATAASGAPVSPQAAPVPSQRPHHGD----PQDGPSHSDSWLTVTPGTSRPLSTSSGVFT 354
                   P+S  +   P  +   G      Q GPS       ++  T + +S      T
Sbjct: 294 GPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS------ALSDPTVKTISVDHS-ST 346

Query: 355 AATGPTPAAFDTSVSAPSQGIPQGAS----TTPQAPTHPSRVSESTISGAKEETVAT 407
            A+ P+  +    + + ++ +P   +      P     PS +S  T S +    VAT
Sbjct: 347 GASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVAT 403


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 132/500 (26%), Positives = 182/500 (36%), Gaps = 95/500 (19%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            SPR +L    S T PG    +    T H +    TP+P   PS A AP+   T       
Sbjct: 2198 SPRTTLSPA-SSTSPGLQGESTAFQT-HPASTHTTPSP---PSTATAPVEESTTYHRSPG 2252

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------ 146
             T T    A++ T+ HSE S     +P A  TT S       G+   T     P      
Sbjct: 2253 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2312

Query: 147  --PGATSRPTTAPPRTTTRRPPRPPGS------------------SRKGAGNSSRPVPPA 186
              PG+T+ P  +   TT    PR P +                  SR   G++   V PA
Sbjct: 2313 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372

Query: 187  ----PGGHSRSKEGQRG-----------RNPSSTPLGQK------RPLGKIFQIYKGNFT 225
                PG    S                 R P+++  G++      RP      ++  + T
Sbjct: 2373 STTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDST 2432

Query: 226  GSVEPEPSTLTPRTPLWGYSSSPQPQTVA-----ATTVPSNTSWAPTTTSLGPAKDKP-G 279
             S   E ST  P +P    +  P   T A     +TT PS++    T T+L PA+    G
Sbjct: 2433 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG--STGTTLSPARSTTSG 2490

Query: 280  L------RRAAQGGGSTFTSQGG--TPDATAASG----APVSPQAAPVPSQRPHHG---- 323
            L       R +     T T  G   TP  +  S     +P SP A   P+     G    
Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 2550

Query: 324  ----DPQDGPSHSDSW--LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQ 377
                  Q G +H+ ++   T TPG SR  ST+S     +T  T     T+ S PSQ    
Sbjct: 2551 SSTSHSQPGSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTSGPSQESTT 2609

Query: 378  GASTTPQAPTHPSRVSESTISGAKEETVA--------TLTMTDRVPSP----LSTVVSTA 425
              S+     T  S  S + +S  +E T          T    D   S      ST V ++
Sbjct: 2610 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2669

Query: 426  TGNFLNRLVPAGTWKPGTAG 445
            TG+    L PA +  PG  G
Sbjct: 2670 TGSPRTTLSPASSTSPGLQG 2689



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 120/471 (25%), Positives = 175/471 (37%), Gaps = 68/471 (14%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            SPR +L    S T PG    +    T H +    TP+P   PS A AP+   T       
Sbjct: 2672 SPRTTLSPA-SSTSPGLQGESTTFQT-HPASTHTTPSP---PSTATAPVEESTTYHRSPG 2726

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------ 146
             T T    A++ T+ HSE S     +P A  TT S       G+   T     P      
Sbjct: 2727 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2786

Query: 147  --PGATSRPTTAPPRTTTRRPPRPPGSSRK-------GAGNSSRPVPPAPGG-HSRSKEG 196
              PG+T+ P  +   TT    PR P ++         G G  S      PG  HS     
Sbjct: 2787 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846

Query: 197  QR---GRNPSSTPLGQKRPLGKIFQIYKGNFTGSVE-PEPSTLTPR-----TPLWGYSSS 247
                 G +  ST +    P      ++  + T SV   EP+T   R     T L+   S+
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST 2906

Query: 248  PQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAP 307
                T  +T  P     +P +T  G     P     A  G  + T     P ++ ++G  
Sbjct: 2907 TSGLTEESTAFPG----SPASTQTG----LPATLTTADLGEESTT----FPSSSGSTGTT 2954

Query: 308  VSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGP-TPAAFDT 366
            +SP  +            +  PS +++  T  PG+    S S    T  T P +P A  +
Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTET--TTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 3012

Query: 367  SVSAPSQGIPQGASTTPQAP--THPSRVSES-TISGAKEE----------TVATLTMTDR 413
              +  S G+ + +ST+   P  TH +   +S T SG  +E          T ATL+    
Sbjct: 3013 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGST 3072

Query: 414  VPSPL---STVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRAT 461
              S L   ST   ++ G+    L+P  T   G       + E   P H +T
Sbjct: 3073 TASSLGQQSTTFHSSPGDTETTLLPDDTITSG-------LVEASTPTHSST 3116



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 120/471 (25%), Positives = 175/471 (37%), Gaps = 68/471 (14%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            SPR +L    S T PG    +    T H +    TP+P   PS A AP+   T       
Sbjct: 3755 SPRTTLSPA-SSTSPGLQGESTAFQT-HPASTHTTPSP---PSTATAPVEESTTYHRSPG 3809

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------ 146
             T T    A++ T+ HSE S     +P A  TT S       G+   T     P      
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 3869

Query: 147  --PGATSRPTTAPPRTTTRRPPRPPGSSRK-------GAGNSSRPVPPAPGG-HSRSKEG 196
              PG+T+ P  +   TT    PR P ++         G G  S      PG  HS     
Sbjct: 3870 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929

Query: 197  QR---GRNPSSTPLGQKRPLGKIFQIYKGNFTGSV-EPEPSTLTPR-----TPLWGYSSS 247
                 G +  ST +    P      ++  + T SV   EP+T   R     T L+   S+
Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDST 3989

Query: 248  PQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAP 307
                T  +T  P     +P +T  G     P     A  G  + T     P ++ ++G  
Sbjct: 3990 TSGLTEESTAFPG----SPASTQTG----LPATLTTADLGEESTT----FPSSSGSTGTK 4037

Query: 308  VSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGP-TPAAFDT 366
            +SP  +            +  PS +++  T  PG+    S S    T  T P +P A  +
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTET--TTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 4095

Query: 367  SVSAPSQGIPQGASTTPQAP--THPSRVSES-TISGAKEE----------TVATLTMTDR 413
              +  S G+ + +ST+   P  TH +   +S T SG  +E          T ATL+    
Sbjct: 4096 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155

Query: 414  VPSPL---STVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRAT 461
              S L   ST   ++ G+    L+P  T   G       + E   P H +T
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITSG-------LVEASTPTHSST 4199



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 121/475 (25%), Positives = 170/475 (35%), Gaps = 79/475 (16%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            SPR +L    S T PG    +    T H +    TP+P   PS A AP+   T       
Sbjct: 1115 SPRTTLSPA-SSTSPGLQGESTAFQT-HPASTHTTPSP---PSTATAPVEESTTYHRSPG 1169

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------ 146
             T T    A++ T+ HSE S     +P A  TT S       G+   T     P      
Sbjct: 1170 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 1229

Query: 147  --PGATSRPTTAPPRTTTRRPPRPP------------------GSSRKGAGNSSRPVPPA 186
              PG+T+ P  +   TT    PR P                   +SR   G++   V PA
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289

Query: 187  ----PGGHSRSK---EGQRGRN-----PSSTPLG---------QKRPLGKIFQIYKGNFT 225
                PG    S       RG       P ST              RP      ++  + T
Sbjct: 1290 STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDST 1349

Query: 226  GSVEPEPSTLTPRTPLWGYSSSPQPQTVA-----ATTVPSNTSWAPTTTSLGPAKDKPGL 280
             S   E ST  P +P    +  P   T A     +TT PS++    T T L PA      
Sbjct: 1350 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS--GSTGTKLSPA------ 1401

Query: 281  RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVT- 339
            R    G     T    +P +T  +  P SP    +  +          P  + S  T T 
Sbjct: 1402 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 1461

Query: 340  --------PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSR 391
                       S+P ST +  F  +T  +  + + + S  SQG  + A+ +P + T  S 
Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE-ATLSPGSTTASSL 1520

Query: 392  VSES-TISGAKEETVATLTMTDRVPSPL---STVVSTATGNFLNRLVPAGTWKPG 442
              +S T   +  +T  TL   D + S L   ST   ++TG+    L PA +   G
Sbjct: 1521 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1575



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 122/483 (25%), Positives = 179/483 (37%), Gaps = 54/483 (11%)

Query: 45   TPPGTMVTA-PHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAAT 103
            TP  +  T     ST   S    +     PPS  A P+   T        T T    A++
Sbjct: 4207 TPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASS 4266

Query: 104  VTAPHSESSLSTGPAPAAMAT-------TSSKPEGRPRGQ--AAPTILLTKPPGATSRPT 154
             T   SE S +   +P A  T        +S   G P     ++ +   T  PG+T+   
Sbjct: 4267 TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 4326

Query: 155  TAPPRTTTRRPPRPPGSSRKGAGNSSRPV-PPAPGGHSRSKEGQRGRNPSSTPLGQKRPL 213
             +   TT    PR P ++   A  +S  V   +   HSR         PSST +      
Sbjct: 4327 LSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQE 4386

Query: 214  GKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGP 273
                    G+   ++ P  +T +   P    +    P +   T +P NT+ +    +  P
Sbjct: 4387 STASHSSPGSTDTTLSPGSTTASSLGP-ESTTFHSSPGSTETTLLPDNTTASGLLEASTP 4445

Query: 274  AKDKPGLRRAAQGGGSTFTSQGGT------PDATAASGAPVSPQAAPVPSQRPHHGDPQD 327
                 G          + T QG +      P++   + AP +  +A V      HG P  
Sbjct: 4446 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSS 4505

Query: 328  GPSHSDSWLTVTPGTSRPLST--SSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQA 385
             P+   S  + T G S   +T  SS V TA T P+PA   TS      G+ + ++T   +
Sbjct: 4506 TPTTHFSASSTTLGRSEESTTVHSSPVATATT-PSPARSTTS------GLVEESTTYHSS 4558

Query: 386  P--THPSRVSES-TISGAKEETVATLTMT----DRVPSPLSTVV-----------STATG 427
            P  T      ES T SG  EE+  + + T       PS  S +V           STAT 
Sbjct: 4559 PGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 4618

Query: 428  NFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDIAWVILAISV--PISSCSV 485
            +F +    +G  +  TA + S  A G       TI L       V+L  S   PISS S+
Sbjct: 4619 HFPDSSTTSGRSEESTASHSSQDATG-------TIVLPARSTTSVLLGESTTSPISSGSM 4671

Query: 486  LLT 488
              T
Sbjct: 4672 ETT 4674



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 123/457 (26%), Positives = 173/457 (37%), Gaps = 59/457 (12%)

Query: 73   PPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMAT-------T 125
            PP   AAP+   T        T T    A++ T   SE S +   +P A  T        
Sbjct: 3153 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 3212

Query: 126  SSKPEGRPRGQ--AAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPV 183
            +S   G P     ++ +   T  PG+T+    +   TT    PR P ++   A  +S  V
Sbjct: 3213 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 3272

Query: 184  -PPAPGGHSRSKEGQRGRNPSSTPL---------GQKRPLGKIFQIYKGNFT-GSVEPEP 232
               +   HSR         P ST +             P      +  G+ T  S+ PE 
Sbjct: 3273 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES 3332

Query: 233  STL-----TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGG 287
            +T      +  T L   +++      A+T V S+T    TT S       P      QG 
Sbjct: 3333 TTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS-------PAGSTTRQGE 3385

Query: 288  GSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLS 347
             +TF S   + D T    AP +  +A V      HG P   P+   S  + T G S   +
Sbjct: 3386 STTFQSWPNSKDTTP---APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST 3442

Query: 348  T--SSGVFTAATGPTPAAFDTS----VSAPSQGIPQGASTT--PQAPTHPSRVSESTIS- 398
            T  SS V TA T P+PA   TS     S      P    T   P++ T   R  EST S 
Sbjct: 3443 TVHSSPVATATT-PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSH 3501

Query: 399  GAKEETVA-----TLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEG 453
             +   T++     T  + +   S  S+  STAT +F +    +G  +  TA + S  A G
Sbjct: 3502 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 3561

Query: 454  DKPQHRATICLSKMDIAWVILAISV--PISSCSVLLT 488
                   TI L       V+L  S   PISS S+  T
Sbjct: 3562 -------TIVLPARSTTSVLLGESTTSPISSGSMETT 3591



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 112/451 (24%), Positives = 162/451 (35%), Gaps = 47/451 (10%)

Query: 73   PPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMAT-------T 125
            PP   AAP+   T        T T    A++ T   SE S +   +P A  T        
Sbjct: 1596 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 1655

Query: 126  SSKPEGRPRGQ--AAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPV 183
            +S   G P     ++ +   T  PG+T+    +   TT    PR P ++   A  +S  V
Sbjct: 1656 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 1715

Query: 184  -PPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLW 242
               +   HSR         P ST +              G+   ++ P  +T +   P  
Sbjct: 1716 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP-E 1774

Query: 243  GYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGT----- 297
              +    P +   T +P NT+ +    +  P     G          + T QG +     
Sbjct: 1775 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 1834

Query: 298  -PDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST--SSGVFT 354
             P +     AP +  +A V      HG P   P+   S  + T G S   +T  SS V T
Sbjct: 1835 WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 1894

Query: 355  AATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET-VATLTMTDR 413
            A T P+PA   TS           +  + Q    P     ST SG  EE+  +  + T  
Sbjct: 1895 ATT-PSPARSTTSGLVEESTAYHSSPGSTQTMHFP---ESSTASGRSEESRTSHSSTTHT 1950

Query: 414  VPSPLSTVV--------------STATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHR 459
            + SP ST                STAT +F +    +G  +  TA + S  A G      
Sbjct: 1951 ISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG------ 2004

Query: 460  ATICLSKMDIAWVILAISV--PISSCSVLLT 488
             TI L       V+L  S   PISS S+  T
Sbjct: 2005 -TIVLPARSTTSVLLGESTTSPISSGSMETT 2034



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 109/476 (22%), Positives = 172/476 (36%), Gaps = 75/476 (15%)

Query: 48   GTMVTAPHSSTRHTSVVMLTPNP-----DGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            G   T  HSST HT  +   P+      + P S  ++P +T T      P + T S  + 
Sbjct: 854  GEESTTSHSSTTHT--ISSAPSTTSALVEEPTSYHSSPGSTATTH---FPDSSTTSGRSE 908

Query: 103  TVTAPHS-ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              TA HS + +  T   PA   T+    E      ++ ++  T  PG+T+ P  +   TT
Sbjct: 909  ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 968

Query: 162  TRRPPRPP------------GSSRKGAGNSSRP------------VPPAPGGHSRSKEGQ 197
                PR P            G S +   + SRP              P    HS +    
Sbjct: 969  FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 1028

Query: 198  RGRN-----PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTL---------------TP 237
             G       P+ST                G+   ++ P  +T                + 
Sbjct: 1029 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGST 1088

Query: 238  RTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGT 297
             T L+  S++      A+T V S+T  +P TT    +   PGL    QG  + F +    
Sbjct: 1089 HTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGL----QGESTAFQTH--- 1140

Query: 298  PDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAAT 357
            P +T  + +P S   APV     +H  P   P+      + T G S   ST       A+
Sbjct: 1141 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSPDAS 1199

Query: 358  GPTPAAFDTSVSAPSQG----IPQGA---STTPQAPTHPSRVSESTI----SGAKEETVA 406
            G TP++  ++ S   +     I  G+   +T P + T P     ST       +   T++
Sbjct: 1200 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 1259

Query: 407  TLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATI 462
              +MT       ST   +  G+  + + PA T  PG +   + V    +     T+
Sbjct: 1260 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 1315



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 107/459 (23%), Positives = 174/459 (37%), Gaps = 63/459 (13%)

Query: 36   ESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTH 95
            E     PS +       +P  ST    V   TP+         +P +T T    G P T 
Sbjct: 4022 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS-------RLSPSSTETTTLPGSPTTP 4074

Query: 96   TISTIAATV-TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPT 154
            ++S  + T  T+P S        A  + ATT+S       G +  +      PG+T   T
Sbjct: 4075 SLSEKSTTFYTSPRSPD------ATLSPATTTSS------GVSEESSTSHSQPGST-HTT 4121

Query: 155  TAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLG 214
              P  TTT    + P +S    G++   +  +PG  + S  GQ+     S+P   +  L 
Sbjct: 4122 AFPDSTTTSGLSQEPTTSHSSQGSTEATL--SPGSTTASSLGQQSTTFHSSPGDTETTLL 4179

Query: 215  KIFQIYKGNFTGSVEPEPST---LTPRTPLWGYSSSPQPQTVAATTVP--SNTSWAPTTT 269
                I  G    S     ST    T  TP    S+  Q ++    + P  S+T+ +P +T
Sbjct: 4180 PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPST 4239

Query: 270  SLGPAK------DKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHH- 322
            +  P +       +P          S+ T+ G + ++T    +P +   A  P++     
Sbjct: 4240 TAVPVEVSTTYHSRPSSTPTTHFSASS-TTLGRSEESTTVHSSPGATGTALFPTRSATSV 4298

Query: 323  --GDPQDGPSHSDSW-LTVTPGTSRPLSTSSGVFTAATGP-TPAAFDTSVSAPSQGIPQG 378
              G+P   P  S S   T  PG++     S    T  + P +P    +  S  S G+ + 
Sbjct: 4299 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 4358

Query: 379  ASTT------------PQAPTHPSRVSESTIS----GAKEETVATLTMTDRVPSPLSTVV 422
            ++T+            P + T P    EST S    G+ + T++  + T     P ST  
Sbjct: 4359 STTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF 4418

Query: 423  STATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRAT 461
             ++ G+    L+P  T   G       + E   P H +T
Sbjct: 4419 HSSPGSTETTLLPDNTTASG-------LLEASTPVHSST 4450



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 95/402 (23%), Positives = 151/402 (37%), Gaps = 28/402 (6%)

Query: 52   TAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSES 111
            TA HSS   T  ++L   P    +      +T +P + G   T  +    +T T   SE 
Sbjct: 3551 TASHSSQDATGTIVL---PARSTTSVLLGESTTSPISSGSMETTALP--GSTTTPGLSEK 3605

Query: 112  SLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGS 171
            S +   +P + ATT S       G +  +      PG+T   T  P  TTT    R   +
Sbjct: 3606 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST-HTTAFPDSTTTPGLSRHSTT 3664

Query: 172  SRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPE 231
            S    G++   + PA    S S +     + SS         G    +  G  + +    
Sbjct: 3665 SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSS 3724

Query: 232  PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
            P +    T L+  S++      A+T V S+T  +P TT    +   PGL+  +    +  
Sbjct: 3725 PGST--HTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGESTAFQTHP 3781

Query: 292  TSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSG 351
             S   TP   + +        APV     +H  P   P+      + T G S   ST   
Sbjct: 3782 ASTHTTPSPPSTA-------TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFH 3833

Query: 352  VFTAATGPTPAAFDTSVSAPSQG----IPQGA---STTPQAPTHPSRVSESTI----SGA 400
                A+G TP++  ++ S   +     I  G+   +T P + T P     ST       +
Sbjct: 3834 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS 3893

Query: 401  KEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPG 442
               T++  +MT       ST   +  G+  + + PA T  PG
Sbjct: 3894 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 3935



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 108/444 (24%), Positives = 160/444 (36%), Gaps = 65/444 (14%)

Query: 40   VLPSGTPPGTMVTAPH-------SSTRHTSVVMLTPNPDGPPSQAAAPMATP-----TPR 87
            +L + TP  +   +PH       S+TR          P    +  A P  T      +  
Sbjct: 1799 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1858

Query: 88   AEGHPP-THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            + G P  T T    A++ T   SE S +   +P A ATT S       G    +      
Sbjct: 1859 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1918

Query: 147  PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP 206
            PG            +T+    P  S+  G    SR        HS S        PS+T 
Sbjct: 1919 PG------------STQTMHFPESSTASGRSEESRT------SHS-STTHTISSPPSTTS 1959

Query: 207  LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAP 266
               + P    +    G+   +  P+ ST + R+     S S Q  T     +P+ ++   
Sbjct: 1960 ALVEEPTS--YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT-GTIVLPARST--- 2013

Query: 267  TTTSLGPAKDKP---GLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHG 323
            T+  LG +   P   G        GST T+ G +  +T    +P SP     P+     G
Sbjct: 2014 TSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHSSPRSPATTLSPASTTSSG 2072

Query: 324  DPQD--------GPSHSDSW--LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQ 373
              ++        G +H+ ++   T TPG SR  ST+S     +T  T     T+ S PSQ
Sbjct: 2073 VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTSGPSQ 2131

Query: 374  GIPQGASTTPQAPTHPSRVSESTISGAKEET--------VATLTMTDRVPS----PLSTV 421
                  S+     T  S  S + +S  +E T          T    D   S      ST 
Sbjct: 2132 ESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR 2191

Query: 422  VSTATGNFLNRLVPAGTWKPGTAG 445
            V ++TG+    L PA +  PG  G
Sbjct: 2192 VHSSTGSPRTTLSPASSTSPGLQG 2215



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 99/408 (24%), Positives = 153/408 (37%), Gaps = 40/408 (9%)

Query: 52   TAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSES 111
            TA HSS   T  ++L   P    +      +T +P + G   T  +    +T T   SE 
Sbjct: 1994 TASHSSQDATGTIVL---PARSTTSVLLGESTTSPISSGSMETTALP--GSTTTPGLSEK 2048

Query: 112  SLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGS 171
            S +   +P + ATT S       G +  +      PG+T   TTA P +TT      PG 
Sbjct: 2049 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH--TTAFPDSTTT-----PGL 2101

Query: 172  SRKGAGNSSRP----VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPL--GKIFQIYKGNFT 225
            SR    + S P        P   + S   Q      S+P      L  G    +  G  +
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 2161

Query: 226  GSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQ 285
             +    P +    T L+  S++      A+T V S+T  +P TT    +   PGL+  + 
Sbjct: 2162 TTFHSSPGST--HTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGLQGEST 2218

Query: 286  GGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRP 345
               +   S   TP   + +        APV     +H  P   P+      + T G S  
Sbjct: 2219 AFQTHPASTHTTPSPPSTA-------TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2271

Query: 346  LSTSSGVFTAATGPTPAAFDTSVSAPSQG----IPQGA---STTPQAPTHPSRVSESTI- 397
             ST       A+G TP++  ++ S   +     I  G+   +T P + T P     ST  
Sbjct: 2272 -STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2330

Query: 398  ---SGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPG 442
                 +   T++  +MT       ST   +  G+  + + PA T  PG
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPG 2378



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 104/444 (23%), Positives = 165/444 (37%), Gaps = 65/444 (14%)

Query: 40   VLPSGTPPGTMVTAPH-------SSTRHTSVVMLTPNPDGPPSQAAAPMATP-----TPR 87
            +L + TP  +   +PH       S+TR          P+   +  A P  T      +  
Sbjct: 3356 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTT 3415

Query: 88   AEGHPP-THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            + G P  T T    A++ T   SE S +   +P A ATT S       G    +      
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 3475

Query: 147  PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP 206
            PG+T         TT+ R       S     +++  +  AP   S   E      P+S  
Sbjct: 3476 PGSTQTMHFPESDTTSGRGEE----STTSHSSTTHTISSAPSTTSALVE-----EPTS-- 3524

Query: 207  LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAP 266
                      +    G+   +  P+ ST + R+     S S Q  T     +P+ ++   
Sbjct: 3525 ----------YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT-GTIVLPARST--- 3570

Query: 267  TTTSLGPAKDKP---GLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHG 323
            T+  LG +   P   G        GST T+ G +  +T    +P SP     P+     G
Sbjct: 3571 TSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHSSPRSPATTLSPASTTSSG 3629

Query: 324  DPQD--------GPSHSDSW--LTVTPGTSR--------PLSTSSGVFTAATGPTPAAFD 365
              ++        G +H+ ++   T TPG SR        P ST + +  A+T  + ++ +
Sbjct: 3630 VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE 3689

Query: 366  TSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSP----LSTV 421
            ++ S  S G    A  +P + T  S   EST   +   +  T    D   S      ST 
Sbjct: 3690 STTSHSSSGSTDTA-LSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTR 3748

Query: 422  VSTATGNFLNRLVPAGTWKPGTAG 445
            V ++TG+    L PA +  PG  G
Sbjct: 3749 VHSSTGSPRTTLSPASSTSPGLQG 3772



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 96/406 (23%), Positives = 151/406 (37%), Gaps = 42/406 (10%)

Query: 44   GTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA- 102
            G  P T  + P S+  HT++        G   ++ A   +P     G P T T + +   
Sbjct: 2409 GEEPTTFHSRPAST--HTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 2466

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
            + T P S  S  T  +PA   T+    E  P   +  +   T  PG+ + P+ +   TT 
Sbjct: 2467 STTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 2526

Query: 163  RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKG 222
               PR P ++   A  +S  V         S+E       SST   Q            G
Sbjct: 2527 YTSPRSPDATLSPATTTSSGV---------SEE-------SSTSHSQP-----------G 2559

Query: 223  NFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRR 282
            +   +  P+ ST TP       +S   P +   T +P++T+ +  +     +   PG   
Sbjct: 2560 STHTTAFPD-STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618

Query: 283  AAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGT 342
             A   GST T+     ++T    +P S      P      G  +       S  +     
Sbjct: 2619 TALSPGST-TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2677

Query: 343  SRPLSTSSGVFTAAT--GPTPAAFDTSVSAPSQG-IPQGASTT----PQAPTHPSRVSES 395
            S   STS G+   +T     PA+  T+ S PS    P   STT    P +       + S
Sbjct: 2678 SPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2737

Query: 396  TISGAKEETVATLTMTDRVPSPLSTVVSTATG---NFLNRLVPAGT 438
            T SG  E++    +  D   +  S+  ST +G   +  +R+ P  T
Sbjct: 2738 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST 2783



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 107/473 (22%), Positives = 166/473 (35%), Gaps = 71/473 (15%)

Query: 40   VLPSGTPPGTMVTAPH-------SSTRHTSVVMLTPNPDGPPSQAAAPMATP-----TPR 87
            +L + TP  +   +PH       S+TR          P+   +  A P  T      +  
Sbjct: 4439 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTT 4498

Query: 88   AEGHPP-THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            + G P  T T    A++ T   SE S +   +P A ATT S       G    +      
Sbjct: 4499 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 4558

Query: 147  PG-------------------------ATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSR 181
            PG                         +T+   ++ P TT+     P          ++ 
Sbjct: 4559 PGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 4618

Query: 182  PVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPL 241
              P +     RS+E     +          P      +  G  T S  P  S     T L
Sbjct: 4619 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS--PISSGSMETTAL 4676

Query: 242  WGYSSSPQPQTVAATTVPSNTSWAPTT------TSLGPAKDKPGLRRAAQGGGST----- 290
             G +++P   +  +TT  S+ S  PTT      T+LG +++   +  +     +T     
Sbjct: 4677 PGSTTTP-GLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR 4735

Query: 291  FTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG-PSHSDSWLTVT--PGTS---- 343
             T+ G   ++TA   +P S Q    P      G  ++   SHS +  T++  P T+    
Sbjct: 4736 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 4795

Query: 344  -RPLSTSSGVFTAATGPTPAAFDTS----VSAPSQGIPQGASTTPQAPTH---PSRVSES 395
              P S  S   + AT   P +  TS     S  S   P     TP  P H     R++ES
Sbjct: 4796 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP-LPAHFTTSGRIAES 4854

Query: 396  T---ISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAG 445
            T   IS    ET    T T    S  ST++ +++ +    L PA       +G
Sbjct: 4855 TTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISG 4907



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 112/482 (23%), Positives = 170/482 (35%), Gaps = 43/482 (8%)

Query: 94  THTISTIAATVTAPHSESSLSTGPAPAAMATT-------SSKPEGRPRGQ--AAPTILLT 144
           T T   + ++  + HSE S  +   P A  TT       +S   G P+     + ++  T
Sbjct: 206 TATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETT 265

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPV-PPAPGGHSRSKEGQRGRNPS 203
             PG+T+    +   TT    PR P  +   A  +S  V   +   HSR         P 
Sbjct: 266 ALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPD 325

Query: 204 STPLGQKRPLGKIFQIYKGNFTGSVEP---EPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
           ST +              G+   ++ P    PS+L P +  +  S    P     T +P 
Sbjct: 326 STTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSS----PGYTKTTRLPD 381

Query: 261 NTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQG------GTPDATAASGAPVSPQAAP 314
           NT+ +    +  P     G         S+ T +G        P +   S AP    +A 
Sbjct: 382 NTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF 441

Query: 315 VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST--SSGVFTAATGPTPAAFDTSVSAPS 372
           V     +H  P   P+   S  + T G S   +   SS V TA T P PA   TS     
Sbjct: 442 VKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATT-PPPARSATSGHVEE 500

Query: 373 QGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPL-STVVSTATGNFLN 431
                 +  + Q    P     ST SG  EE+      T    S   ST  + A  ++ +
Sbjct: 501 STAYHRSPGSTQTMHFP---ESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHS 557

Query: 432 RLVPAGTWKPGTAGNISHVAEGDKPQH-----RATICLSKMDIAWVILAISV--PISSCS 484
            L    T     +  IS  +E  K  H      AT  L       V++  S   PISS S
Sbjct: 558 SLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGS 617

Query: 485 VLLTVCCMKRKKKTANPENNLSYWNNTITMDYFNRHAVELPREIQSLETSEDQLSEPRSP 544
            + T        K    E + +++++  + D        LP  + S   SE+  +    P
Sbjct: 618 -METTALPGSTTKPGLSEKSTTFYSSPRSPD-----TTHLPASMTSSGVSEESTTSHSRP 671

Query: 545 AN 546
            +
Sbjct: 672 GS 673



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 92/421 (21%), Positives = 149/421 (35%), Gaps = 82/421 (19%)

Query: 47  PGTMVTAPHSSTRHTSVVMLTPNPD---GPPSQAAAPMATPTPRAEGHP-PTHTISTIAA 102
           PG+  TA  S  + T+      +PD    P    ++ ++  +  +   P PTHTI+   +
Sbjct: 268 PGSTTTAGLSE-KSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS 326

Query: 103 TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
           T     S+ S ++   P +  TT S     P      +      PG T + T  P  TTT
Sbjct: 327 TTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYT-KTTRLPDNTTT 385

Query: 163 RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKG 222
                       G   +S PV      HS +       +PSS+   +  P    FQ +  
Sbjct: 386 -----------SGLLEASTPV------HSSTGSPHTTLSPSSSTTHEGEP--TTFQSWPS 426

Query: 223 NFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRR 282
           +   S  P              S +       +TT  S+ S  PTT              
Sbjct: 427 SKDTSPAP--------------SGTTSAFVKLSTTYHSSPSSTPTTHF------------ 460

Query: 283 AAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGT 342
                 ++ T+ G + ++T    +PV+    P P++    G  ++  ++  S     PG+
Sbjct: 461 -----SASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRS-----PGS 510

Query: 343 SRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVS--------E 394
           ++ +       T+      A F  S +      P   +       H S  S         
Sbjct: 511 TQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDS 570

Query: 395 STISGAKEETVATLTMTDRV----------PSPL---STVVSTATGNFLNRLVPAGTWKP 441
           STISG  EE+ A+ +  D +          PS L   ST    ++G+     +P  T KP
Sbjct: 571 STISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKP 630

Query: 442 G 442
           G
Sbjct: 631 G 631



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 107/477 (22%), Positives = 167/477 (35%), Gaps = 75/477 (15%)

Query: 40   VLPSGTPPGTMV----TAPHSS-TRHTSVVMLTPNPDGPPSQAAAPMATP-TPRAEGHPP 93
            VLP+G+ P  +V     +P SS +  T+ +  +    G   ++    ++P +P     P 
Sbjct: 594  VLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPA 653

Query: 94   THTISTIAATVTAPHSE-SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSR 152
            + T S ++   T  HS   S  T   P +        E      +      T  PG+T+ 
Sbjct: 654  SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTA 713

Query: 153  PTTAPPRTTTRRPPR-------PPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST 205
             +  P  TT    P        P  ++  G   +S PV      HS +      R+P +T
Sbjct: 714  SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPV------HSST------RSPHTT 761

Query: 206  --PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLT-----PRTPLWGYSSSPQPQTVAATTV 258
              P G     G+    +    +    P P T T     P T   G  SS     ++A + 
Sbjct: 762  LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARST 821

Query: 259  PSNTSWAPTTTSLGPAKDK----PGLRRAAQGGGSTFTSQGGT-------PDATAA-SGA 306
             S      TT    P   +    P     +  G  + TS   T       P  T+A    
Sbjct: 822  TSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEE 881

Query: 307  PVSPQAAPVPSQRPHHGD----------------PQDG------PSHSDSWLTVTPGTSR 344
            P S  ++P  +   H  D                 QD       P+ S + + +   T+ 
Sbjct: 882  PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 941

Query: 345  PLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTT--PQAPTHPSRVSESTISGAKE 402
            P+S+ S   TA  G T     +  S      P+  +TT  P + T      EST S ++ 
Sbjct: 942  PISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRP 1001

Query: 403  ETVATLTMTDRVPSP----LSTVVSTATGNFLNRLVPAGTWK--PGTAGNISHVAEG 453
             +  T    D   +P     ST   ++ G+    L+PA T    P      SH + G
Sbjct: 1002 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSG 1058



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 91/410 (22%), Positives = 147/410 (35%), Gaps = 55/410 (13%)

Query: 43  SGTPPGTMVTAPHSSTRHT----------SVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
           +G+P  T+  +P SST H           S    +P P G  S       T        P
Sbjct: 399 TGSPHTTL--SPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTP 456

Query: 93  PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSR 152
            TH     A++ T  HSE S     +P A ATT         G    +    + PG+T +
Sbjct: 457 TTHFS---ASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGST-Q 512

Query: 153 PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRP 212
               P  +TT             +G+S           S +  G      SSTP      
Sbjct: 513 TMHFPESSTT-------------SGHSE---------ESATFHGSTTHTKSSTPSTTAAL 550

Query: 213 LGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLG 272
               +    G+   +   + ST++ R+     +S   P  +A T +P+ ++ +       
Sbjct: 551 AHTSYHSSLGSTETTHFRDSSTISGRSE-ESKASHSSPDAMATTVLPAGSTPSVLVGDST 609

Query: 273 PAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHS 332
           P+    G        GST T  G +  +T    +P SP    +P+     G  ++     
Sbjct: 610 PSPISSGSMETTALPGST-TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEES---- 664

Query: 333 DSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRV 392
                 T   SRP ST +  F  +T     + +++ S  S G P   + +P + T  S  
Sbjct: 665 ------TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG-PTDTTLSPGSTTASSLG 717

Query: 393 SESTISGAKEETVATLTMTDRVPS----PLSTVVSTATGNFLNRLVPAGT 438
            E T   ++  +  T  + D   +      S  V ++T +    L PAG+
Sbjct: 718 PEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGS 767



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 108/438 (24%), Positives = 163/438 (37%), Gaps = 62/438 (14%)

Query: 48   GTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATV--- 104
            G   T  HS    T   +L   PD   +      + P   +   P T T+S   +T    
Sbjct: 717  GPEYTTFHSRPGSTETTLL---PDNTTASGLLEASMPVHSSTRSPHT-TLSPAGSTTRQG 772

Query: 105  --TAPHS-ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              T  HS  SS  T PAP    TTS+  E       +P+ + T    A S  +     +T
Sbjct: 773  ESTTFHSWPSSKDTRPAPPT--TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 830

Query: 162  TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN---------PSSTPLGQKRP 212
            T      PGS++      +   P +     R +E     +         PS+T    + P
Sbjct: 831  TYHSS--PGSTQ------TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 882

Query: 213  LGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLG 272
                +    G+   +  P+ ST + R+     S S Q  T     +P+ ++   T+  LG
Sbjct: 883  TS--YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT-GTIVLPARST---TSVLLG 936

Query: 273  PAKDKP---GLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD-- 327
             +   P   G        GST T+ G +  +T    +P SP     P+     G  ++  
Sbjct: 937  ESTTSPISSGSMETTALPGST-TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 995

Query: 328  ------GPSHSDSW--LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGA 379
                  G +H+ ++   T TPG SR  ST+S     +T  T     T+ S PSQ      
Sbjct: 996  TSRSRPGSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 1054

Query: 380  STTPQAPTHPSRVSESTISGAKEETVA--------TLTMTDRVPSP----LSTVVSTATG 427
            S++    T  S  S + +S  +E T          T    D   S      ST V ++TG
Sbjct: 1055 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 1114

Query: 428  NFLNRLVPAGTWKPGTAG 445
            +    L PA +  PG  G
Sbjct: 1115 SPRTTLSPASSTSPGLQG 1132



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 40/169 (23%), Positives = 65/169 (38%), Gaps = 27/169 (15%)

Query: 47   PGTM-------VTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMAT----PTPRAEGHPPTH 95
            PG+M        T P  S + T +   + +PD   S A+   ++    PT        TH
Sbjct: 4861 PGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTH 4920

Query: 96   TISTIAATVTAPHSESSLS---------TGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            T +  A+T T+  S+ S +         T  +P ++ T+S   E         + L T  
Sbjct: 4921 TTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVS 4980

Query: 147  PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNS-------SRPVPPAPG 188
            P +T+ P  +   TT    P    ++     N+       S P P +PG
Sbjct: 4981 PASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPG 5029


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 106/427 (24%), Positives = 148/427 (34%), Gaps = 73/427 (17%)

Query: 17  LILALTEALAFAIQEPSPRESLQVLPS--GTPPGTMVTAPHSSTRHTSVVML-------- 66
           L   L   L  A   PS   SLQ LPS   TPP    T+  S T   +   L        
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389

Query: 67  -TPNPDGPPSQAA---------------APMATPTPRAEGHPPTHTISTIAATVTAPHSE 110
            TP P  PP+ A                +P+ATP+P+A      H +    +   +P  +
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449

Query: 111 SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILL-------------TKPPGATSRPTTAP 157
           +  S  PA   ++ +++ P   P   AAP + +               PP     P  AP
Sbjct: 450 APFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508

Query: 158 PRTTTRRPPRPPGSSRKGAGNSSRPVPPA--PGGHSRSKEGQRGRNPSSTPLGQKRPL-- 213
           P    + PP+ P  +       + P PPA  PG    S       +P +TP  Q  P+  
Sbjct: 509 PLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567

Query: 214 GKIFQIYKGNFTGSVEPEPSTLTPRTPLW----GYSSSPQPQTVAATTVPSNTSWAPTTT 269
             + Q+       S    P+   PR P         S P+     A   P   S +P++T
Sbjct: 568 APLLQV-----PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622

Query: 270 SLGP--------AKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVP----- 316
             GP        A   P   R    G     +    PDA  A+  P +    P P     
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682

Query: 317 --SQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
                P    P  GP  +D   T+   T  P S +        GP+P    TS    + G
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYE-TEGPESATPAPGALDPGPSPG---TSGGKAAAG 738

Query: 375 IPQGAST 381
              GAS+
Sbjct: 739 AGAGASS 745



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 100/373 (26%), Positives = 131/373 (35%), Gaps = 59/373 (15%)

Query: 32  PSPRESLQVLPSGTPPGTMVTAPHSSTRH----TSVVMLTPNPDGPPSQAAAPMATPTPR 87
           PSP  +LQ   S  PP T+   PHSS+      T + +  P+P  PPS    P    TP 
Sbjct: 307 PSPSAALQ---SQAPP-TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP- 361

Query: 88  AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
               P   T S  + T+ A HS       P+P      +  P+  P     P   L  PP
Sbjct: 362 ----PSQATTSLGSPTLQATHSFL-----PSPPLSPLATPPPQAPPALALPP---LQAPP 409

Query: 148 GATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPL 207
              + P  +P  T + + P         A  S  P PP       S       +PS+TP 
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPVSPSATPP 467

Query: 208 GQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPT 267
            Q  P      +        V P P    P +P    S++P PQ       P      P 
Sbjct: 468 SQAPPSLAAPPL-------QVPPSPPASPPMSP----SATPPPQAPPPLAAP------PL 510

Query: 268 TTSLGPAKDKPGLRR-AAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQ 326
             +  P +  P L     Q   S   S  G    + ++  P+SP A P P   P    P 
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP- 569

Query: 327 DGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAP 386
                    L   P    P   +S    A   P     DTSVS P   +    +  P  P
Sbjct: 570 ---------LLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTL----ALAPGPP 612

Query: 387 THPSRVSESTISG 399
             PSR   ST+SG
Sbjct: 613 PPPSRSPSSTLSG 625



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 82/310 (26%), Positives = 116/310 (37%), Gaps = 56/310 (18%)

Query: 138 APTILLTKPPGATSRPTTAPPRT-----TTRRPPRPPGSSRKGA-GNSSRPVPPAPGGHS 191
           AP +L  +PPG+   P    P             R P + R G  G ++ P      G +
Sbjct: 21  APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 192 RSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQ 251
           RS  G   RNP+S P    R              G   P     +P     G  SSP   
Sbjct: 81  RSA-GTSSRNPASRPPASGR--------------GERAPPAKNTSP-----GPVSSPG-- 118

Query: 252 TVAATTVPSNTSW------APTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
             + TT P           A  T + G A + P  +R+A   G+   + G TP   + + 
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAP--KRSALSAGARRDTSGPTPGTPSPAM 176

Query: 306 APVSPQAA-------PVPSQRPHHGDPQDGPSHS------DSWLTVTPGTSRPLSTSSGV 352
           A  S  A        P PS RP    P +GP  S       S    +P   R  S   G+
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 353 FTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTD 412
              A+    ++  T +S+P++  P  A  TP+AP HPS+     +   +   V T    D
Sbjct: 235 QRPASRSLSSSA-TPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQV-TPPRKD 291

Query: 413 RVPS--PLST 420
             P+  PLS+
Sbjct: 292 AAPALGPLSS 301



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 93/392 (23%), Positives = 134/392 (34%), Gaps = 62/392 (15%)

Query: 74  PSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEG-R 132
           P+  A  + TP P     PP             P + ++L    A  A+     KP   R
Sbjct: 17  PAARAPGLLTPRPPGSPRPPP------------PVTPAALRVLGAAGAVGR---KPLAER 61

Query: 133 PRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSR 192
             G    TI  + P    +R      R    RPP      R     ++ P P +  G + 
Sbjct: 62  AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121

Query: 193 SKE-----GQRGRNPS---STPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPR------ 238
                   GQ+G   S   +   G+     K   +  G    +  P P T +P       
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181

Query: 239 -------TPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
                   P    S+ P+P T       S+ S   TT     A+ +P      Q   S  
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241

Query: 292 TSQGGTPDATAASGAPV---SPQAAPVPSQRPHHG-----DPQDGPSHSDSWLTVTPGTS 343
            S   TP ++ A   P    +P+A   PSQ    G      PQ  P   D+   + P +S
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 344 RPLST---SSGVFTAATGPTPAAFDTS-----------VSAPSQGIPQGASTTPQAPTHP 389
            PL+T   S+ + + A    PA   +S           ++ PS   P    T P  P  P
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361

Query: 390 SRVSESTISGAKEETVATLTMTDRVP-SPLST 420
              S++T S       AT +     P SPL+T
Sbjct: 362 P--SQATTSLGSPTLQATHSFLPSPPLSPLAT 391



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 88/366 (24%), Positives = 131/366 (35%), Gaps = 75/366 (20%)

Query: 43  SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           SG  PGT   A    +R     +  P P        AP A P P  EG  P  ++S+ + 
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRP--------APSARPRPPTEG--PRKSVSSASE 214

Query: 103 TVTAPHSES-----------------SLSTGPAP-AAMATTSSKPEGRPRGQAAPTILLT 144
             T   S +                 SLS+   P ++ A +     G PR  A P+    
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS--QP 272

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
           KP G  +     PP+ T   PPR   +   G  +SS    P+P   S + + Q      +
Sbjct: 273 KPKGLQA---LRPPQVT---PPRKDAAPALGPLSSSPLATPSP---SAALQSQAPPTLPA 323

Query: 205 TPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSW 264
           TP             +  + T  +   P  L P +P    S+ P  QT+ +   P  T  
Sbjct: 324 TP-------------HSSSLTCQL-ATPLPLAPPSP----SAPPSLQTLPS---PPATPP 362

Query: 265 APTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGD 324
           +  TTSLG     P L+       +T +     P +  A+  P +P A  +P  +     
Sbjct: 363 SQATTSLG----SPTLQ-------ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 411

Query: 325 PQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQ 384
           P   P         TP    P + +  +  A   P P+    +  +P    P   S TP 
Sbjct: 412 PASPPLSP----LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 385 APTHPS 390
           +   PS
Sbjct: 468 SQAPPS 473


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 94/398 (23%), Positives = 146/398 (36%), Gaps = 41/398 (10%)

Query: 22  TEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTP------------N 69
           T + A     PS    +++LP  +P G +     +    T+ +  TP            +
Sbjct: 289 TPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRAS 348

Query: 70  PDGPPSQAAAPMATPTPRA-EGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSK 128
           P G PS  A+P  TP+  +  G P T +++ +++T +   +    S    P+  + T   
Sbjct: 349 PTGKPS-TASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKP 407

Query: 129 PEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT-TRRPPR--PPGSSRKGAGNSSRPVPP 185
           P   P G  + T  +TK   +T+ PT  PPR + T  PPR  P G+  + +   ++    
Sbjct: 408 PRASPTGMLSRT-SITK-MDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTAS 465

Query: 186 APGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTP--RTPLWG 243
             G  S S     G   +++P G            + + T        T TP   +P W 
Sbjct: 466 PTG--SPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTW- 522

Query: 244 YSSSPQPQTVAATTVPSN--TSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGG---TP 298
                 P T + T  PS      +P+  +L     +  L R       T  S+     TP
Sbjct: 523 -----TPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTP 577

Query: 299 DATAASGAPVSPQAAPVPSQRPHHGDPQDG---PSHSDSWLTVTPGTSRPLSTSSGVFTA 355
                +  P S     +PS+    G P         S + +T TP  + P  T       
Sbjct: 578 STVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPT 637

Query: 356 ATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVS 393
            T P  +   T   A   G P  AS T      PSR S
Sbjct: 638 GTPPRASPTGTPPRASPTGTPPRASPTGT----PSRAS 671



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 116/436 (26%), Positives = 160/436 (36%), Gaps = 70/436 (16%)

Query: 35  RESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPT 94
           R SL + PS     TM +   S TR      LT  P         P A+PT       PT
Sbjct: 136 RASLSMTPSTAAALTMPSRA-SLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPT 194

Query: 95  HTISTIA-------ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
              ST +       A++T   S +S  TG  P A + T S P        +  +L+  PP
Sbjct: 195 GMPSTASLTKMDSTASITRTLSRAS-PTGTPPRA-SPTGSPPRASLSMMPSTALLIRTPP 252

Query: 148 GATSRPTTAPPRTT----------TRRPPRPPGSSRKGA-GNSSRPVPPAPGGHSRSKEG 196
            A+  PT    RT+          TR P RP  +S  G    +S  + P+     R    
Sbjct: 253 RAS--PTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRML-- 308

Query: 197 QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLT-PRTPLWGYSSSPQPQTVAA 255
                P ++P G          + K + T S+   P   +  RTP    S + +P T + 
Sbjct: 309 -----PRASPTGMLSRT----SLTKMDSTASISRTPPRASITRTPSRA-SPTGKPSTASP 358

Query: 256 TTVPSNTS--WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAA 313
           T  PS  S   +P+T SL               G S+  S  GTP   + +G P +    
Sbjct: 359 TGTPSRASPTGSPSTASL--------------TGLSSTASPTGTPPRASPTGTPSTASLT 404

Query: 314 PVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQ 373
             P        P+  P+   S  ++T   S    T +    + TG  P A  T    PS+
Sbjct: 405 RKP--------PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPT--GTPSR 454

Query: 374 GIPQGASTTPQAPTHPSRV----SESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNF 429
             P G  +T      PS      S ST S     + A+LT   R PS  S     +T + 
Sbjct: 455 ASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLT---RTPSRASLTKMESTASI 511

Query: 430 LNRLVPAG-TWKPGTA 444
                 A  TW P TA
Sbjct: 512 TRTPSRASPTWTPSTA 527



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 114/437 (26%), Positives = 172/437 (39%), Gaps = 84/437 (19%)

Query: 19  LALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTP---NPDGPPS 75
           L++T + A A+  PS R SL    + TPP   +T     T  T+ +  TP   +P G PS
Sbjct: 139 LSMTPSTAAALTMPS-RASL----TRTPPRASLTM----TPSTASLTRTPPRASPTGMPS 189

Query: 76  QAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRG 135
           + +     PT    G P T +++ + +T +   + S  S    P   + T S P      
Sbjct: 190 RTS-----PT----GMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSM 240

Query: 136 QAAPTILLTKPPGATSRPTTAPPRTT----------TRRPPRPPGSSRKGA-GNSSRPVP 184
             +  +L+  PP A+  PT    RT+          TR P RP  +S  G    +S  + 
Sbjct: 241 MPSTALLIRTPPRAS--PTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMT 298

Query: 185 PAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLT-PRTPLWG 243
           P+     R         P ++P G          + K + T S+   P   +  RTP   
Sbjct: 299 PSTASLMRML-------PRASPTGMLSRTS----LTKMDSTASISRTPPRASITRTPSRA 347

Query: 244 YSSSPQPQTVAATTVPSNTS--WAPTTTSLGPAKDKPGLRRAAQGGGST-FTSQGGTPDA 300
            S + +P T + T  PS  S   +P+T SL       GL   A   G+    S  GTP  
Sbjct: 348 -SPTGKPSTASPTGTPSRASPTGSPSTASL------TGLSSTASPTGTPPRASPTGTPST 400

Query: 301 TAASGAPVSPQAAPV----------------PSQRPHHGDPQDGPSHSDSWLTVTPGTSR 344
            + +  P  P+A+P                 P++ P    P   P  +    T TP  + 
Sbjct: 401 ASLTRKP--PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASP--TGTPSRAS 456

Query: 345 PLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVS----ESTISGA 400
           P  T S   TA+   +P+   +   +PS   P G+ +       PSR S    EST S  
Sbjct: 457 PTGTQS---TASPTGSPST-ASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASIT 512

Query: 401 KEETVATLTMTDRVPSP 417
           +  + A+ T T    SP
Sbjct: 513 RTPSRASPTWTPSTASP 529



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 116/458 (25%), Positives = 169/458 (36%), Gaps = 87/458 (18%)

Query: 34  PRESLQVLPSG-----TPPGTMVTAPHSSTRHTSV-----VMLTPN------PDGPPSQA 77
           PR SL ++PS      TPP    T   S T  T +     +  TP+      P G PS+A
Sbjct: 234 PRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRA 293

Query: 78  AAPMATPT-------PRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSK-- 128
           +  M   T       PRA    PT  +S    ++T   S +S+S  P  A++  T S+  
Sbjct: 294 SLSMTPSTASLMRMLPRAS---PTGMLSR--TSLTKMDSTASISRTPPRASITRTPSRAS 348

Query: 129 PEGRPRGQAAPTILLTK--PPGA-----------TSRPTTAPPRTT----------TRRP 165
           P G+P   A+PT   ++  P G+           T+ PT  PPR +          TR+P
Sbjct: 349 PTGKP-STASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKP 407

Query: 166 PRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLG---QKRPLGKIFQIYKG 222
           PR   +      + ++    A    +  +    G  P ++P G   +  P G        
Sbjct: 408 PRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGT------- 460

Query: 223 NFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWA--PTTTSLGPAKDKPGL 280
             T S    PST +P         +  P T + T  PS  S    P+  SL   +    +
Sbjct: 461 QSTASPTGSPSTASP---------TGSPSTASPTGSPSRASLTRTPSRASLTKMESTASI 511

Query: 281 RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTP 340
            R       T+T     P   + +G+P +  A   PS+      P      S + LT TP
Sbjct: 512 TRTPSRASPTWT-----PSTASPTGSPSTALAMGSPSRAALTRTP------SRASLTRTP 560

Query: 341 GTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGA 400
             +  L+T S      T  T        SA   G+P   S T    +      +ST S  
Sbjct: 561 SRAS-LTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASIT 619

Query: 401 KEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
           +    A+ T T    SP  T    +      R  P GT
Sbjct: 620 RTPPRASPTETPPRASPTGTPPRASPTGTPPRASPTGT 657



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 103/423 (24%), Positives = 153/423 (36%), Gaps = 34/423 (8%)

Query: 34  PRESLQVLPSGTPPGTMVTAPH--SSTRHTSVVMLTPNPDGPPSQAAAPMATPT---PRA 88
           PR SL+     T   +++ +P   S TR  S  +LT  P     +   P A+ T   PRA
Sbjct: 54  PRASLK---GTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRA 110

Query: 89  E--GHPPTHTI--STIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
                P T ++  S   A++T   S +SLS  P+ AA  T  S+       +  P   LT
Sbjct: 111 SLMRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRAS---LTRTPPRASLT 167

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
             P   S   T P  + T  P R   +      + ++    A    + S+    G  P +
Sbjct: 168 MTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRA 227

Query: 205 TPLGQKRPLGKIFQIYKGNFTGSVEPE--PSTLTPRTPLWGYSSSP-------QPQTVAA 255
           +P G   P   +  +          P   P+ +  RT L    S+        +P T + 
Sbjct: 228 SPTGSP-PRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASP 286

Query: 256 TTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPV 315
           T  PS  S + T ++    +  P   RA+  G  + TS        + S  P        
Sbjct: 287 TGTPSRASLSMTPSTASLMRMLP---RASPTGMLSRTSLTKMDSTASISRTPPRASITRT 343

Query: 316 PSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGI 375
           PS+    G P      S +  T TP  + P  + S         T +   T   A   G 
Sbjct: 344 PSRASPTGKP------STASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGT 397

Query: 376 PQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVP 435
           P  AS T + P        S  S  K ++ A+ T T    SP  T    +     +R  P
Sbjct: 398 PSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASP 457

Query: 436 AGT 438
            GT
Sbjct: 458 TGT 460


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 106/422 (25%), Positives = 164/422 (38%), Gaps = 40/422 (9%)

Query: 22   TEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPM 81
            TE  +  I  PS  E   +L S     T VT+P +ST  T+ V    + + P + +    
Sbjct: 791  TEGTSMPISTPS--EGSPLLTSIPVSITPVTSPEASTLSTTPV----DSNSPVTTSTEVS 844

Query: 82   ATPTPRAEGHPPTHTIST---------IAATVTAPHSESSLSTGPAPAAMATTSSKPEGR 132
            ++PTP      PT T S          ++ T+ A  + S+LST P   +   T+S     
Sbjct: 845  SSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARS 904

Query: 133  PRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSR 192
                +  T + T  PG  S P T+ P +TT        +      ++S PV  +    S 
Sbjct: 905  SPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSS 964

Query: 193  SKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTL--TP---RTPL-WGYSS 246
                +    P+STP     PL         + T     E STL  TP    TPL     +
Sbjct: 965  PTTAEGTSIPTSTPSEGTTPLTST----PVSHTLVANSEASTLSTTPVDSNTPLTTSTEA 1020

Query: 247  SPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA-SG 305
            S  P T   T++P++T          P++    L R         +S+  T   T A + 
Sbjct: 1021 SSPPPTAEGTSMPTST----------PSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS 1070

Query: 306  APVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFD 365
             PV+  +    S     G      ++S+     TP TS P+ST   V + A+  +    D
Sbjct: 1071 TPVTTYSQASSSSTTADGTSMPTSTYSEG---STPLTSVPVSTRLVVSSEASTLSTTPVD 1127

Query: 366  TSVSAPSQGIPQGASTTPQAPTHP-SRVSESTISGAKEETVATLTMTDRVPSPLSTVVST 424
            TS+   +      + TT +  + P S  SE T   A      TL ++    +  +T V +
Sbjct: 1128 TSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS 1187

Query: 425  AT 426
             T
Sbjct: 1188 KT 1189



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 106/446 (23%), Positives = 159/446 (35%), Gaps = 51/446 (11%)

Query: 28   AIQEPSPRESLQV----LPSGTPPGTMVTAPHSSTRHTSVVML--TPNPDGPPSQAAAPM 81
            A   P+  E   +    L  GT P T +   H+   ++ V  L  TP     P   +   
Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEA 2316

Query: 82   ATPTPRAEGHP-PTHTIST---------IAATVTAPHSESSLSTGPAPAAMATTSSKPEG 131
            ++P P AEG   PT T S          ++ T+ A    S+LST PA  +   T+    G
Sbjct: 2317 SSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAG 2376

Query: 132  RPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHS 191
                 A  T + T      S P T+ P +T         +      ++S PV  +    S
Sbjct: 2377 SSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASS 2436

Query: 192  RSKEGQRGRNPSSTPLGQKRPLGKI---FQIYKGNFTGSVEPEP-STLTPRTPLWGYSSS 247
                 +    P+S P     PL  +         +  G++   P  T TP T     SSS
Sbjct: 2437 SPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSS 2496

Query: 248  PQPQTVAATTVPSNTSWAPTT--TSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
              P T     VP +T+   +T  TS+  +        A+    +   S      +T  S 
Sbjct: 2497 --PTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISS 2554

Query: 306  APVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST----SSGVFTAATGPTP 361
            +  S +   +P+     G               TP  S P+ST    SS   T +T P  
Sbjct: 2555 SATSAEGTSMPTSTYSEGS--------------TPLRSMPVSTKPLASSEASTLSTTPVD 2600

Query: 362  AAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTIS------GAKEETVATLTMTDRVP 415
             +   + S  +   P  A  T    + PS VS S  S             +TL+ T   P
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTT---P 2657

Query: 416  SPLSTVVSTATGNFLNRLVPAGTWKP 441
                T+V+T+TG   +     G+  P
Sbjct: 2658 VDTRTLVTTSTGTSSSPTTAEGSSMP 2683



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 116/472 (24%), Positives = 173/472 (36%), Gaps = 56/472 (11%)

Query: 19   LALTEALAFAIQEPSPRES---LQVLPSGTPP------GTMVTAPHSSTRHTSVVMLTPN 69
            L+ T A   +I   SP E    L  +P  T P       T+ T P  S  +T V   T  
Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDS--NTLVTTSTEA 3436

Query: 70   PDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKP 129
               P       + T T  +EG  P  +I  ++ T  A    S+LST P   +   T+S P
Sbjct: 3437 SSSPTIAEGTSLPTSTT-SEGSTPL-SIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSP 3494

Query: 130  EGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGG 189
                   A  T + T   G  S P T  P +TT      P +S + +  S+ PV      
Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT------PVASSEASTLSTTPVDSNTFV 3548

Query: 190  HSRSKEGQRGRNPSSTPLGQKRPLG-----KIFQIYKGNFTGSVEPEPST-----LTPRT 239
             S S+          T +    P           +     T S    PST      TP T
Sbjct: 3549 TSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVT 3608

Query: 240  PLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTP- 298
                 +S+P P  V   T+P +T    +T           +  +  G  ST      TP 
Sbjct: 3609 TSTQSNSTPTPPEV--ITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPV 3666

Query: 299  -DATAASGAPVSPQAAPVPSQRPHHGD-PQDGPSHSDSWLTVTPG---------TSRPLS 347
              +T  S +PV+P+   +P   P  G  P      S + +T + G         TS P++
Sbjct: 3667 ITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVT 3726

Query: 348  TSSGVFTAATGPTPAAFDTSVSAPSQ----GIPQGASTTP-------QAPTHPSRVSEST 396
            TS+   +++   T  +   SVS P +    G     STTP         P+ PS  +  +
Sbjct: 3727 TSTEAISSSA--TLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMS 3784

Query: 397  ISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNIS 448
            ++ A E + +  T+      P+ST    +T      + P     P  A  +S
Sbjct: 3785 MTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 101/425 (23%), Positives = 154/425 (36%), Gaps = 45/425 (10%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP---MATPTPRAEGHPPTHTIST 99
            S TP  +   +  S+T   + + +T + +G  S   A    M   TP     P T   S 
Sbjct: 2877 STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLT---SI 2933

Query: 100  IAATVTAPHSESS-LSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPP 158
            + +TV    SE+S LST P       T+S         A  T +    PG    P T+  
Sbjct: 2934 LVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMS 2993

Query: 159  RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
             +T         +  +   ++S PV  +    S     +    P STP     PL  I  
Sbjct: 2994 VSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI-- 3051

Query: 219  IYKGNFTGSVEPEPSTL--------TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTS 270
                + T    PE STL        +P       SSSP P     T++P +T    +T  
Sbjct: 3052 --PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP--AEGTSMPISTYSEGSTPL 3107

Query: 271  LGPAKDKPGLRRAAQGGGSTFTSQGGTP--DATAASGAPVSPQAAPVPSQRPHHG----- 323
             G       +  +A    ST      TP   +T A  +P + +   +P+  P  G     
Sbjct: 3108 TGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLT 3167

Query: 324  ----DPQDGPSHSDSWLTVTP-GTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQG 378
                      S  DS L+ TP  TS P++TS    T AT        +S +A    IP  
Sbjct: 3168 YMPVSTMLVVSSEDSTLSATPVDTSTPVTTS----TEAT--------SSTTAEGTSIPTS 3215

Query: 379  ASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
              +    P     VS + ++ ++   ++T  +    P   ST  S++        +P  T
Sbjct: 3216 TPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTST 3275

Query: 439  WKPGT 443
               G+
Sbjct: 3276 PSEGS 3280



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 90/396 (22%), Positives = 143/396 (36%), Gaps = 27/396 (6%)

Query: 61   TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPA 120
            T V   T     P +     + T TP +EG  P  T + ++ T+ A    S+LST P  +
Sbjct: 953  TPVTTSTEATSSPTTAEGTSIPTSTP-SEGTTPL-TSTPVSHTLVANSEASTLSTTPVDS 1010

Query: 121  AMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
                T+S     P   A  T + T  P   S P T  P +TT        +      ++S
Sbjct: 1011 NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTS 1070

Query: 181  RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKI-----FQIYKGNFTGSVEPEPSTL 235
             PV       S S        P+ST      PL  +       +     T S  P  +++
Sbjct: 1071 TPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI 1130

Query: 236  TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQG 295
               T      +S  P T   T++P++   +  TT L        L  +++    + T   
Sbjct: 1131 PVTT---STEASSSPTTAEGTSIPTSPP-SEGTTPLASMPVSTTLVVSSEANTLSTTPVD 1186

Query: 296  GTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTA 355
                   ++ A   P  A V S       P   P    + LT  P    P++ SS   T 
Sbjct: 1187 SKTQVATSTEASSPPPTAEVTSM------PTSTPGERSTPLTSMPVRHTPVA-SSEASTL 1239

Query: 356  ATGPTPAAFDTSVSAPSQGIPQGA-------STTPQAPTHPSRVSEST--ISGAKEETVA 406
            +T P   +   + SA +   P  A       STT +  T  + +  ST  ++  +  T+ 
Sbjct: 1240 STSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLL 1299

Query: 407  TLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPG 442
            T  +  + P   S  VS++        +P  T+  G
Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEG 1335



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 108/455 (23%), Positives = 169/455 (37%), Gaps = 54/455 (11%)

Query: 28  AIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTS-----VVMLTPNPDGPPSQAAAPMA 82
           +I   +P E    L +      +V +  +ST  T+       + T +     S  A   +
Sbjct: 559 SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTS 618

Query: 83  TPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPA----PAAMATTSSKPEGRPRGQAA 138
            PT        T T  +++ T+ A    S+LST P     P   +T ++       G + 
Sbjct: 619 MPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSM 678

Query: 139 PTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQR 198
           PT   T+     S P T+ P  TT        +      ++S PV  +    S       
Sbjct: 679 PTSTYTEG----STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADG 734

Query: 199 GRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTV 258
              P+STP     PL  +  + K   T S   E STL+  TPL          T    T 
Sbjct: 735 ASMPTSTPSEGSTPLTSM-PVSKTLLTSS---EASTLS-TTPL---------DTSTHITT 780

Query: 259 PSNTSWAPTTTS------LGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA-SGAPVSPQ 311
            +  S +PTTT         P++  P L           + +  T   T   S +PV+  
Sbjct: 781 STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS 840

Query: 312 AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST----SSGVFTAATGP----TPAA 363
                S  P  G      ++S+     TP TS P+ST    +S + T +T P    TP  
Sbjct: 841 TEVSSSPTPAEGTSMPTSTYSEG---RTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVT 897

Query: 364 FDTSV-SAP--SQGIPQGASTTPQAPTHPSRVSEST--ISGAKEETVATLTMTDRVPSPL 418
             T   S+P  S+G     ST  +  T  + + +ST  +  ++  T++   +    P   
Sbjct: 898 NSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTT 957

Query: 419 STVV----STATGNFLNRLVPAGTWKPGTAGNISH 449
           ST      +TA G  +    P+    P T+  +SH
Sbjct: 958 STEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSH 992



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 91/408 (22%), Positives = 144/408 (35%), Gaps = 59/408 (14%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVML--TPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            S TP  T +    S+   +S      T  P  PPS+   P+A+                +
Sbjct: 1122 STTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS--------------MPV 1167

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
            + T+      ++LST P  +     +S     P   A  T + T  PG  S P T+ P  
Sbjct: 1168 STTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVR 1227

Query: 161  TTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIY 220
             T        +      ++S PV  +    S     +    P+ST       L  I    
Sbjct: 1228 HTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSI---- 1283

Query: 221  KGNFTGSVEPEPSTLT--------PRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLG 272
              + T    PE STL         P       SSSP P     T++P++T     T    
Sbjct: 1284 PVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP--AEGTSMPTSTYSEGRTPLTS 1341

Query: 273  PAKDKPGLRRAAQGGGSTFTSQGGTP--DATAASGAPVSPQAAPVPSQRPHHGDPQDGPS 330
               +   +  +A    ST      TP   +T A  +P + +   +P+  P  G       
Sbjct: 1342 IPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG------- 1394

Query: 331  HSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTS-------------VSAPSQGIPQ 377
                    TP TS P+ST+  V + A+  +    DTS              +A    IP 
Sbjct: 1395 -------TTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPT 1447

Query: 378  GASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTA 425
               +  + P     VS + ++ ++  T++T  +    P   ST VS++
Sbjct: 1448 STPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSS 1495



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 121/478 (25%), Positives = 178/478 (37%), Gaps = 71/478 (14%)

Query: 18   ILALTEALAFAIQEPS------PRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPD 71
            + A TEA +    E S      P E   +L S     T V +P +ST  T+ V    + +
Sbjct: 1604 VTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPV----DSN 1659

Query: 72   GPPSQAAAPMATPTPRAEGHPPTHTIS---------TIAATVTAPHSESSLSTGPAPAAM 122
             P   +    ++PTP      PT T +         T+  T  A  + S+LST P   + 
Sbjct: 1660 SPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNST 1719

Query: 123  ATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP 182
              T+S         +  T +    P   + P T+ P +TT        +      ++S P
Sbjct: 1720 PVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTP 1779

Query: 183  VPPAPGGHSRSKEGQRGRNPSS------TPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLT 236
            V  +    S     +    P+S      TPL    P+           T S  P  S  +
Sbjct: 1780 VTTSTEATSSPTTAEGTSIPTSTLSEGMTPL-TSTPVSHTLVANSEASTLSTTPVDSN-S 1837

Query: 237  PRTPLWGYSSSPQPQ--TVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQ 294
            P       SSSP P   T  AT+ PS  S A T+  +        +  +     ST  + 
Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTT----VASSETNTLSTTPAV 1893

Query: 295  GGTPDATAA--SGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST---- 348
              TP  T A  S +P +   + +P+  P  G P              P TS P+ST    
Sbjct: 1894 TSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP--------------PLTSIPVSTTTVA 1939

Query: 349  SSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATL 408
            SS + T +T  T A   T V+  SQ     AS++P      S  + +   G+   T   L
Sbjct: 1940 SSEINTLST--TLADTRTPVTTYSQ-----ASSSPTTADGTSMPTPAYSEGSTPLTSMPL 1992

Query: 409  TMTDRVPSPLSTVVSTATGNFLNRLVPA-----GTWKPGTAGNISHVAEGDKPQHRAT 461
            + T  V S  ST+ +T     ++   PA     G+  P TAG  S   +   P  R T
Sbjct: 1993 STTLVVSSEASTLSTTP----VDTSTPATTSTEGSSSPTTAGGTS--IQTSTPSERTT 2044



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 96/425 (22%), Positives = 152/425 (35%), Gaps = 39/425 (9%)

Query: 43  SGTPPGTMVTAPHSSTRHTSVVMLTP-----------NPDGPPSQAAAPMATPTPRAEGH 91
           + TP  TM  A    T   S + +TP            P   P+ A A     +  +EG 
Sbjct: 337 TSTPASTMPVA----TSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGS 392

Query: 92  PPTHTISTIAATVTAPHSESSLSTGPAPA-AMATTSSKPEGRPRGQAAPTILLTKPPGAT 150
            P  T   ++  + A    S+ ST P  +    TT+S+    P   A  T + T  P   
Sbjct: 393 TPL-TNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPT-TAEDTSIATSTPSEG 450

Query: 151 SRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQK 210
           S P T+ P +TT        +      +S   V  +    S     +    P+STP    
Sbjct: 451 STPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGS 510

Query: 211 RPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTS 270
            PL  +      +       E STL+          +   +  +++T P  TS   +T S
Sbjct: 511 TPLTSM----SVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPS 566

Query: 271 LG--PAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG 328
            G  P  + P   R      ++ TS   TP   A S   V+  +    S     G     
Sbjct: 567 EGSTPLTNMPVSTRLVVSSEASTTST--TP---ADSNTFVTTSSEASSSSTTAEGTSMPT 621

Query: 329 PSHSDSWLTVTP-GTSRPLSTSSGVFTAATGP----TPA-----AFDTSVSAPSQGIPQG 378
            ++S+   T+T    S  L  SS   T +T P    TP      A  +S +A    +P  
Sbjct: 622 STYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTS 681

Query: 379 ASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
             T    P     V+ + ++ ++  T++T  +    P   ST  S++        +P  T
Sbjct: 682 TYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTST 741

Query: 439 WKPGT 443
              G+
Sbjct: 742 PSEGS 746



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 102/439 (23%), Positives = 158/439 (35%), Gaps = 47/439 (10%)

Query: 38   LQVLPSGTPP------GTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH 91
            L+ +P  T P       T+ T P  ++   +    T +        + P++TP+  +   
Sbjct: 2576 LRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVS--- 2632

Query: 92   PPTHTISTIAATVTAPHSESS-LSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGAT 150
              T   S + +T+    SE+S LST P       T+S         A  + + T  PG  
Sbjct: 2633 --TSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER 2690

Query: 151  SRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQK 210
            S P T    +TT        +      ++S PV  +    S     +      STP    
Sbjct: 2691 STPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGS 2750

Query: 211  RPLGKI----FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAA--TTVPSNTSW 264
             PL  I      +     +        T  P T     SSSP    V +  T+ PS TS 
Sbjct: 2751 TPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETS- 2809

Query: 265  APTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTP--DATAASGAPVSPQAAPVPSQRPHH 322
             P T+   P    P +  +  G  ST      TP   +T AS +P + +   VP      
Sbjct: 2810 TPLTSM--PVNHTP-VASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASE 2866

Query: 323  GDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTT 382
            G          + LT  P ++ P++ SS   T +T P   +   + S      P  A  T
Sbjct: 2867 G---------STLLTSIPVSTTPVA-SSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGT 2916

Query: 383  PQAPTHPSRVSES---------TISGAKEETVATLTMTDRVPSPLSTVVS----TATGNF 429
                + PS VS            ++G++  T++T  +  R P   S   S    TA G  
Sbjct: 2917 SMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTS 2976

Query: 430  LNRLVPAGTWKPGTAGNIS 448
            +    P     P T+ ++S
Sbjct: 2977 MPISTPGERRTPLTSMSVS 2995



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 102/437 (23%), Positives = 160/437 (36%), Gaps = 43/437 (9%)

Query: 41   LPSGTPPGTMVTAPHSSTRHTSVVMLTP-----NPDGPPSQAAAPMATPTPRAEGHPPTH 95
            +P  T P  +VT+  S+   T V   TP          P+ A       +  +EG  P  
Sbjct: 2225 MPVSTMP--VVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLT 2282

Query: 96   TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTT 155
            +I  ++ T+ A    S+LST P  +    T+S     P   A  T + T      + P T
Sbjct: 2283 SIP-VSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLT 2341

Query: 156  APPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGK 215
              P +TT        +      ++S PV       S          P+ST      PL  
Sbjct: 2342 RMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTS 2401

Query: 216  I----FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL 271
            +      +     +        T TP T     SSS  P T   T++P++     TT   
Sbjct: 2402 VPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSS--PTTAEGTSIPTSPPSEGTTPLA 2459

Query: 272  GPAKDKPGLRRAAQGGGSTFTSQGGTP--DATAASGAPVSPQAAPVPSQRPHHGD----- 324
                    +  +  G  ST      TP   +T AS +P + +   VP      G      
Sbjct: 2460 SMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTS 2519

Query: 325  ------PQDGPSHSDSWLTVTP-GTSRPLSTSSGVFTAATGPTPAAFDTSV----SAPSQ 373
                  P   P  S   L+ TP  ++ P+ TS+ + ++AT     +  TS     S P +
Sbjct: 2520 IPVSTTPVASPEAST--LSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577

Query: 374  GIPQGASTTPQAPTHPSRVSESTISGA-----KEETVATLTMTDRVPSPLST--VVSTAT 426
             +P   ST P A +  S +S + +  +       ET ++ T       P+ST   VST+ 
Sbjct: 2578 SMP--VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSL 2635

Query: 427  GNFLNRLVPAGTWKPGT 443
             + L   +P  + +  T
Sbjct: 2636 TSILVSTMPVASSEAST 2652



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 102/424 (24%), Positives = 162/424 (38%), Gaps = 61/424 (14%)

Query: 49   TMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPH 108
            T V++  +    TS+ + TP+ +G  +  + P++T T  +       T   + +T    +
Sbjct: 1490 TAVSSSPTPAEGTSIAISTPS-EGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTY 1548

Query: 109  SESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRP 168
            S++S S   A      TS+  EG     + P   +       +  +T P  + T+     
Sbjct: 1549 SQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTAST 1608

Query: 169  PGSSRKGAGNSSRPV-PPAPGG--------HSRSKEGQRGRNPSSTPLGQKRPLGKIFQI 219
              SS   A  SS  +  P+ G          +           S+TP+    P+     I
Sbjct: 1609 EASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV-----I 1663

Query: 220  YKGNFTGSVEPEPSTLTP-------RTPLWGYSSSPQPQTVAATTVPSNT---SWAPTTT 269
                 + S  P   T  P       RTPL   +    P   +A +  S T   +  P TT
Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723

Query: 270  SLGPAKDKPGLRRAAQGGGSTFTSQGGTP--------------DATAASGAPVSPQAAPV 315
            S   A+  P          ST  S+G TP              +A+  S  P+   + PV
Sbjct: 1724 ST-EARSSPTTSEGTSMPNST-PSEGTTPLTSIPVSTTPVLSSEASTLSATPID-TSTPV 1780

Query: 316  PSQRPHHGDP--QDGPSHSDSWLT--VTPGTSRPLS----TSSGVFTAATGP----TPAA 363
             +       P   +G S   S L+  +TP TS P+S     +S   T +T P    +P  
Sbjct: 1781 TTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVV 1840

Query: 364  FDTSVSA---PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
              T+VS+   P++G     ST  +  T  + +  ST + A  ET  TL+ T   P+  ST
Sbjct: 1841 TSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSET-NTLSTT---PAVTST 1896

Query: 421  VVST 424
             V+T
Sbjct: 1897 PVTT 1900



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 122/474 (25%), Positives = 177/474 (37%), Gaps = 82/474 (17%)

Query: 22   TEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPM 81
            T A   ++   +PRE    L S     T V +   +T  T++   T  P    SQA++  
Sbjct: 1909 TTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLAD-TRTPVTTYSQASSSP 1967

Query: 82   AT------PTPR-AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPR 134
             T      PTP  +EG  P  T   ++ T+      S+LST P   +   T+S       
Sbjct: 1968 TTADGTSMPTPAYSEGSTPL-TSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSP 2026

Query: 135  GQAAPTILLTKPPGATSRPTTAPPRTTT-------RRPPRPPGSSRKGAGNSSRPVPPAP 187
              A  T + T  P   + P    P +TT             P  S+    NS+     A 
Sbjct: 2027 TTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSAT 2086

Query: 188  G-GHSRSKEGQRGRNP--------------------SSTPLGQKRPLGKIFQIYKGNF-T 225
              G S +       +P                    S+TP+    P+    ++      T
Sbjct: 2087 AEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPT 2146

Query: 226  GSVEPEPSTLTP-RTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL-----GPAKDKPG 279
                 + ST +  RTPL   +S P   TV A++  S  S  P  TS        A+  P 
Sbjct: 2147 EGTSMQTSTYSDRRTPL---TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPT 2203

Query: 280  LRRAAQGGGSTFTSQGGTP--------------DATAASGAPVSPQAAPVPSQRPHHGDP 325
                     ST  S+G TP              +A+  S  PV   + PV +       P
Sbjct: 2204 TSEGTSMPTST-PSEGSTPFTSMPVSTMPVVTSEASTLSATPVD-TSTPVTTSTEATSSP 2261

Query: 326  --QDGPSHSDSWLT--VTPGTSRPLS----TSSGVFTAATGP----TPAAFDTSVSAP-- 371
               +G S   S L+   TP TS P+S     +S V T +T P    TP    T  S+P  
Sbjct: 2262 TTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPP 2321

Query: 372  -SQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVST 424
             ++G     ST+ +  T  +R+  ST   A  ET +TL+ T   P+  ST V+T
Sbjct: 2322 TAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFET-STLSTT---PADTSTPVTT 2371



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 105/431 (24%), Positives = 151/431 (35%), Gaps = 57/431 (13%)

Query: 43   SGTPPGTMVTAPHSSTRH-TSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            + TP  T   A  S+T   TS+   TP+    P  +     TP   +E       +ST  
Sbjct: 3191 TSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEAS----ILSTTP 3246

Query: 102  ATVTAPHSESSLSTGPAPAAMAT---TSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPP 158
                 P + S+ ++   P A  T   TS+  EG     + P    T     TS  +T P 
Sbjct: 3247 VDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA 3306

Query: 159  RTTT---------RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSK-EGQRGRNPSSTPLG 208
             T+T           PP   G+S   +  S    P      S +          S+TP+ 
Sbjct: 3307 DTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVD 3366

Query: 209  QKRPLGKIFQIYKGNFT--GSVEPEPSTLTPRTPLWGYSSSPQP------QTVAATTVPS 260
               P+    +      T  G+  P  S     TPL     S  P       T++ T V S
Sbjct: 3367 TSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDS 3426

Query: 261  NTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTP--------------DATAASGA 306
            NT      T+   A   P +        ST TS+G TP              +A+  S  
Sbjct: 3427 NT----LVTTSTEASSSPTIAEGTSLPTST-TSEGSTPLSIMPLSTTPVASSEASTLSTT 3481

Query: 307  PVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTV----TPGTSRPLST----SSGVFTAATG 358
            PV   + PV +  P +  P      S    T     TP T+ P+ST    SS   T +T 
Sbjct: 3482 PVD-TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT 3540

Query: 359  PTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSP- 417
            P  +    + S+ +   P     T    + PS  S S  +     T  T +      +P 
Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600

Query: 418  --LSTVVSTAT 426
               ST V+T+T
Sbjct: 3601 VDRSTPVTTST 3611



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 107/450 (23%), Positives = 171/450 (38%), Gaps = 48/450 (10%)

Query: 32   PSPRESLQVLPSGTP-----PGTMVTAPHSSTRHTSVVMLTPNP---DGPPSQAAAPMAT 83
            P P   +  +P+ TP     P T +   H+    +    L+ +P     P + +A   ++
Sbjct: 1200 PPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSS 1259

Query: 84   PTPRAEGHPPTHTIST---------IAAT-VTAPHSESSLSTGPAPAAMATTSSKPEGRP 133
            PT       PT T S          ++ T VT+P + + L+T         TS++    P
Sbjct: 1260 PTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP 1319

Query: 134  ---RGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGH 190
                G + PT   T   G T  P T+ P  TT               ++S PV  +    
Sbjct: 1320 TPAEGTSMPT--STYSEGRT--PLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEAC 1375

Query: 191  SRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQP 250
            S     +    P+S P     PL  I      + T  V  E STL+  TP+   +S+P  
Sbjct: 1376 SSPTTSEGTSMPNSNPSEGTTPLTSI----PVSTTPVVSSEASTLS-ATPV--DTSTPGT 1428

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA-SGAPVS 309
             +  AT+ P+        TS  P++ K  L+           S+  T   T   S +PV 
Sbjct: 1429 TSAEATSSPTTAEGISIPTST-PSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVV 1487

Query: 310  PQAAPVPSQRPHHGD--PQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTS 367
               A   S  P  G       PS   + LT  P ++  +++S      +   TPA   T 
Sbjct: 1488 TSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE---INSLSTTPAVTSTP 1544

Query: 368  VSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET---VATLTMTDRVPSPLSTV-VS 423
            V+  SQ     AS++P      S  + +   G+   T   V+T+ +     + LST  + 
Sbjct: 1545 VTTYSQ-----ASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPID 1599

Query: 424  TATGNFLNRLVPAGTWKPGTAGNISHVAEG 453
            + T    +    + T   G++  IS  +EG
Sbjct: 1600 SKTQVTASTEASSSTTAEGSSMTISTPSEG 1629



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 104/418 (24%), Positives = 155/418 (37%), Gaps = 46/418 (11%)

Query: 46   PPGTM--VTAPHSSTRHTSVVMLTP---NPDGPPSQAAAPMATPTPR-AEGHPPTHTIST 99
            P  TM  V++  S+   T V   TP   + +   S  A   + PT   +EG  P  ++  
Sbjct: 3170 PVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP- 3228

Query: 100  IAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPR 159
            ++ T  A    S LST P  +    T+S         A  T + T  P   S P T+ P 
Sbjct: 3229 VSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPV 3288

Query: 160  TTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQI 219
            +TT        +      ++S PV       S          P+ST      PL  +   
Sbjct: 3289 STTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNM--- 3345

Query: 220  YKGNFTGSVEPEPSTL--TP---RTPL-WGYSSSPQPQTVAATTVP-SNTSWAPTTTSLG 272
               + T  V  E STL  TP    TP+     +S  P T   T++P S+ S   T  +  
Sbjct: 3346 -SFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASM 3404

Query: 273  PAKDKPGLRRAAQGGGST-FTSQGGTPDATAASGAPVSPQAAPVPSQRPHHG-------- 323
            P    P +        +T   S      +T AS +P   +   +P+     G        
Sbjct: 3405 PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMP 3464

Query: 324  -DPQDGPSHSDSWLTVTP-GTSRPLSTSSGVFTAATGPTPAAFDTSV----SAPSQGIPQ 377
                   S   S L+ TP  TS P++TSS   ++ T     +  TS     S P   +P 
Sbjct: 3465 LSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMP- 3523

Query: 378  GASTTPQAPTHPSR-----------VSESTISGAKEETVATLTMTDRVPSPLSTVVST 424
              STTP A +  S            V+ S+ + +   T+   TM    PS  S+ ++T
Sbjct: 3524 -VSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT 3580



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 106/469 (22%), Positives = 166/469 (35%), Gaps = 63/469 (13%)

Query: 33  SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
           S  +S  + PS T   +  T P      T V M TP+ +   S  A     P P  E + 
Sbjct: 121 STSDSTTLFPSSTEDTSSPTTPEG----TDVPMSTPSEESISSTMAFVSTAPLPSFEAYT 176

Query: 93  P-THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTI---------L 142
             T+ +       T+  + SS +T  +     +T+S+         A T+         L
Sbjct: 177 SLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITL 236

Query: 143 LTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP 202
           LT P   ++  T +   +++      P  S       S P+   P         +     
Sbjct: 237 LTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSE-ASTL 295

Query: 203 SSTPLGQKRPLGKIFQIYKGNFT--GSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
           S+TP     P+    +      T  G+  P  +     TPL   +S+P      AT+  S
Sbjct: 296 STTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPL---TSTPASTMPVATSEMS 352

Query: 261 NTSWAPTTTS-LGPAKDKPGLRRAAQGGGSTFT---SQGGTP--------------DATA 302
             S  P  TS L     +P          S  T   S+G TP              +A+ 
Sbjct: 353 TLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAST 412

Query: 303 ASGAPV--------SPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFT 354
            S  PV        + +A+  P+           PS   + LT  P ++ P++ SS    
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVA-SSEASN 471

Query: 355 AATGPTPAAFDTSVSAPSQGIPQGA-------STTPQAPTHPSRVSESTISGAKEETVAT 407
            +T P  +    + S  +   P  A       ST  +  T  + +S ST+  A  E  +T
Sbjct: 472 LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSE-AST 530

Query: 408 LTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKP 456
           L+ T   P   ST V+T++    +   P GT  P      S  +EG  P
Sbjct: 531 LSTT---PVDTSTPVTTSSEASSSSTTPEGTSIP-----TSTPSEGSTP 571



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 39/121 (32%), Positives = 52/121 (42%), Gaps = 14/121 (11%)

Query: 52   TAPHSSTRHTSVVMLTPNPDGPPSQAAAPM-------ATPTPRAEGHPPTHTISTIAATV 104
            T   SS+  T+    T     P    AAP+       A  TPR      T + ST++AT 
Sbjct: 3973 TPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATS 4032

Query: 105  TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRR 164
            T PH+ +S++T P       T S    RP    + TI  T PP  +S P T    +TT  
Sbjct: 4033 T-PHTSTSVTTRPV------TPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVN 4085

Query: 165  P 165
            P
Sbjct: 4086 P 4086



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 84/348 (24%), Positives = 126/348 (36%), Gaps = 45/348 (12%)

Query: 110 ESSLSTGPAPAAMATTSSKPEGRPRGQAAP--TILLTKPPGATSRPTTAPPRTTTRRPPR 167
           ESS+ T   P   +T  +  E R   ++    T L       TS PTT          P 
Sbjct: 95  ESSV-TSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPS 153

Query: 168 PPGSSRKGAGNSSRPVPPAPGGHSRS-KEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTG 226
               S   A  S+ P+P      S + K        +ST         +   I K   T 
Sbjct: 154 EESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKS--TN 211

Query: 227 SVEPEPSTLTPRTPLWGYSS------SPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGL 280
           S    P T  P + +   SS      +   +     T+ +  S +PTT       + P L
Sbjct: 212 SEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTA------EGPSL 265

Query: 281 RRAAQGGGST------------FTSQGGTPDAT-AASGAPV--SPQAAPVPSQRPHHGDP 325
             +A  GGST             +S+  T   T AA+  PV  S +A+  P+       P
Sbjct: 266 SNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIP 325

Query: 326 QDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGA------ 379
               +   + LT TP ++ P++TS  + T +  P   +   + S     +P  A      
Sbjct: 326 TSTYTEGSTPLTSTPASTMPVATSE-MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSML 384

Query: 380 -STTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTAT 426
            ST  +  T  + +  STI  A  E   T T    +P    T V+TA+
Sbjct: 385 TSTLSEGSTPLTNMPVSTILVASSEASTTST----IPVDSKTFVTTAS 428



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 62/236 (26%), Positives = 85/236 (36%), Gaps = 37/236 (15%)

Query: 37   SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHT 96
            S+ V+  G+ PGT +  P S+   +S   + P   G  S    P+ T T      P T +
Sbjct: 3925 SVSVITEGSTPGTTIFIP-STPVTSSTADVFPATTGAVS---TPVITSTEL--NTPSTSS 3978

Query: 97   ISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTA 156
             ST  +  T     +   T  AP    T S+ P   PR  +           ATS P T+
Sbjct: 3979 SSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS-TPRTTSRGCTTSASTLSATSTPHTS 4037

Query: 157  PPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKI 216
               TT                   RPV P+      S        P+  P     P    
Sbjct: 4038 TSVTT-------------------RPVTPSSESSRPSTITSHTIPPTFPPAHSSTP---- 4074

Query: 217  FQIYKGNFTGSVEPEP-STLTPRT-PLWGYSSSPQPQTVAATTVPSNTSWAPTTTS 270
                    + +V PE  +T+T RT P    +S P   TV  T VP+NT+     TS
Sbjct: 4075 --PTTSASSTTVNPEAVTTMTTRTKPSTRTTSFP---TVTTTAVPTNTTIKSNPTS 4125



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 69/313 (22%), Positives = 112/313 (35%), Gaps = 54/313 (17%)

Query: 44   GTPPGTMVTAPHSSTRHTSVVM-----LTPNPDG----PPSQAAAPMATPTPRAEGHPPT 94
            GT    M T    ST  T+V++     ++P+       PP   + P+ T T       P 
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPA 3859

Query: 95   HT--------------ISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPT 140
                            ++T+  + T P S    S    P    +T+  P       + PT
Sbjct: 3860 EVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTA--STPT 3917

Query: 141  ILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGA-----GNSSRPV-------PPAPG 188
            I +      +     + P TT   P  P  SS         G  S PV        P+  
Sbjct: 3918 IPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTS 3977

Query: 189  GHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSP 248
              S +      +  ++  +    PL  +        T S  P     TPRT   G ++S 
Sbjct: 3978 SSSTTTSFSTTKEFTTPAMTTAAPLTYV--------TMSTAPS----TPRTTSRGCTTSA 4025

Query: 249  QPQTVAATTVPSNTSWAPTTTSLGPAKD--KPGLRRAAQGGGSTFTSQGGTPDATAASGA 306
               T++AT+ P +TS + TT  + P+ +  +P    +     +   +   TP  T+AS  
Sbjct: 4026 S--TLSATSTP-HTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASST 4082

Query: 307  PVSPQAAPVPSQR 319
             V+P+A    + R
Sbjct: 4083 TVNPEAVTTMTTR 4095



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 35/135 (25%), Positives = 52/135 (38%), Gaps = 38/135 (28%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            +P  S  V      P +  + P + T HT           PP+                P
Sbjct: 4033 TPHTSTSVTTRPVTPSSESSRPSTITSHTI----------PPT---------------FP 4067

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGAT-- 150
            P H+        + P + S+ ST   P A+ T +++ +   R  + PT+  T  P  T  
Sbjct: 4068 PAHS--------STPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTI 4119

Query: 151  -SRPTTAP--PRTTT 162
             S PT+ P  PRTTT
Sbjct: 4120 KSNPTSTPTVPRTTT 4134



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 62/279 (22%), Positives = 88/279 (31%), Gaps = 44/279 (15%)

Query: 21   LTEALAFAIQEPSPRESLQVLPSGTPPG---------------------TMVTAPHSSTR 59
            LT  L   I   SP E+  +    TPPG                     T +    +S R
Sbjct: 3816 LTTVLISPISVMSPSEASTL---STPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSER 3872

Query: 60   HTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH---PPTHTISTIAATVTAPHSESSLSTG 116
             T +  L  +   P S   A +A+  P        P T T ST    V    S S ++ G
Sbjct: 3873 STPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEG 3932

Query: 117  PAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGA 176
              P       S P         P        GA S P        T  P     S+    
Sbjct: 3933 STPGTTIFIPSTPVTSSTADVFPATT-----GAVSTPVITSTELNT--PSTSSSSTTTSF 3985

Query: 177  GNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLT 236
              +     PA    +          PS TP    R   +         + +  P  ST  
Sbjct: 3986 STTKEFTTPAMTTAAPLTYVTMSTAPS-TP----RTTSRGCTTSASTLSATSTPHTSTSV 4040

Query: 237  PRTPLWGYSSSPQPQTVAATTV-----PSNTSWAPTTTS 270
               P+   S S +P T+ + T+     P+++S  PTT++
Sbjct: 4041 TTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSA 4079


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 121/475 (25%), Positives = 170/475 (35%), Gaps = 79/475 (16%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
            SPR +L    S T PG    +    T H +    TP+P   PS A AP+   T       
Sbjct: 602  SPRTTLSPA-SSTSPGLQGESTAFQT-HPASTHTTPSP---PSTATAPVEESTTYHRSPG 656

Query: 93   PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------ 146
             T T    A++ T+ HSE S     +P A  TT S       G+   T     P      
Sbjct: 657  STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 716

Query: 147  --PGATSRPTTAPPRTTTRRPPRPP------------------GSSRKGAGNSSRPVPPA 186
              PG+T+ P  +   TT    PR P                   +SR   G++   V PA
Sbjct: 717  TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 776

Query: 187  ----PGGHSRSK---EGQRGRN-----PSSTPLG---------QKRPLGKIFQIYKGNFT 225
                PG    S       RG       P ST              RP      ++  + T
Sbjct: 777  STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDST 836

Query: 226  GSVEPEPSTLTPRTPLWGYSSSPQPQTVA-----ATTVPSNTSWAPTTTSLGPAKDKPGL 280
             S   E ST  P +P    +  P   T A     +TT PS++    T T L PA      
Sbjct: 837  TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS--GSTGTKLSPA------ 888

Query: 281  RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVT- 339
            R    G     T    +P +T  +  P SP    +  +          P  + S  T T 
Sbjct: 889  RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 948

Query: 340  --------PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSR 391
                       S+P ST +  F  +T  +  + + + S  SQG  + A+ +P + T  S 
Sbjct: 949  SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTE-ATLSPGSTTASSL 1007

Query: 392  VSES-TISGAKEETVATLTMTDRVPSPL---STVVSTATGNFLNRLVPAGTWKPG 442
              +S T   +  +T  TL   D + S L   ST   ++TG+    L PA +   G
Sbjct: 1008 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 115/464 (24%), Positives = 173/464 (37%), Gaps = 51/464 (10%)

Query: 47  PGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTA 106
           P +  T+ HS    T     T      PS  AA   T    + G   T T     ++  +
Sbjct: 4   PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS--TETTHFRDSSTIS 61

Query: 107 PHSESSLSTGPAPAAMATTSSKPEGRPR---GQAAPTIL------LTKPPGATSRPTTAP 157
             SE S ++  +P AMATT       P    G + P+ +       T  PG+T++P  + 
Sbjct: 62  GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 121

Query: 158 PRTTTRRPPRPPGSSRKGAGNSSRPV-PPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKI 216
             TT    PR P ++   A  +S  V   +   HSR         P ST +         
Sbjct: 122 KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 181

Query: 217 FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKD 276
                G    ++ P  +T +   P +    S +P +   T +P NT+ +    +  P   
Sbjct: 182 SHSSPGPTDTTLSPGSTTASSLGPEYTTFHS-RPGSTETTLLPDNTTASGLLEASMPVHS 240

Query: 277 ---------KPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD 327
                     P      QG  +TF S    P +     AP +  +A V      HG P  
Sbjct: 241 STRSPHTTLSPAGSTTRQGESTTFHS---WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSS 297

Query: 328 GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAA-FDTSVSAPSQGIPQGASTTPQAP 386
            P+   S  + T G    L   S  + ++ G T    F  S +   +G  + ++T+  + 
Sbjct: 298 IPTTHISARSTTSG----LVEESTTYHSSPGSTQTMHFPESDTTSGRG--EESTTSHSST 351

Query: 387 THPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGN 446
           TH       TIS A   T A   + +   S  S+  STAT +F +    +G  +  TA +
Sbjct: 352 TH-------TISSAPSTTSA---LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 401

Query: 447 ISHVAEGDKPQHRATICLSKMDIAWVILAISV--PISSCSVLLT 488
            S  A G       TI L       V+L  S   PISS S+  T
Sbjct: 402 SSQDATG-------TIVLPARSTTSVLLGESTTSPISSGSMETT 438



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 99/417 (23%), Positives = 146/417 (35%), Gaps = 38/417 (9%)

Query: 73   PPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMAT-------T 125
            PP   AAP+   T        T T    A++ T   SE S +   +P A  T        
Sbjct: 1083 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 1142

Query: 126  SSKPEGRPRGQ--AAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPV 183
            +S   G P     ++ +   T  PG+T+    +   TT    PR P ++   A  +S  V
Sbjct: 1143 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 1202

Query: 184  -PPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLW 242
               +   HSR         P ST +              G+   ++ P  +T +   P  
Sbjct: 1203 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP-E 1261

Query: 243  GYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGT----- 297
              +    P +   T +P NT+ +    +  P     G          + T QG +     
Sbjct: 1262 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 1321

Query: 298  -PDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST--SSGVFT 354
             P +     AP +  +A V      HG P   P+   S  + T G S   +T  SS V T
Sbjct: 1322 WPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 1381

Query: 355  AATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET-VATLTMTDR 413
            A T P+PA   TS           +  + Q    P     ST SG  EE+  +  + T  
Sbjct: 1382 ATT-PSPARSTTSGLVEESTAYHSSPGSTQTMHFP---ESSTASGRSEESRTSHSSTTHT 1437

Query: 414  VPSPLSTVV--------------STATGNFLNRLVPAGTWKPGTAGNISHVAEGDKP 456
            + SP ST                S AT +F      +G  +  TA + S    G  P
Sbjct: 1438 ISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP 1494



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 109/476 (22%), Positives = 172/476 (36%), Gaps = 75/476 (15%)

Query: 48  GTMVTAPHSSTRHTSVVMLTPNP-----DGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           G   T  HSST HT  +   P+      + P S  ++P +T T      P + T S  + 
Sbjct: 341 GEESTTSHSSTTHT--ISSAPSTTSALVEEPTSYHSSPGSTATTH---FPDSSTTSGRSE 395

Query: 103 TVTAPHS-ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
             TA HS + +  T   PA   T+    E      ++ ++  T  PG+T+ P  +   TT
Sbjct: 396 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 455

Query: 162 TRRPPRPP------------GSSRKGAGNSSRP------------VPPAPGGHSRSKEGQ 197
               PR P            G S +   + SRP              P    HS +    
Sbjct: 456 FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 515

Query: 198 RGRN-----PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTL---------------TP 237
            G       P+ST                G+   ++ P  +T                + 
Sbjct: 516 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGST 575

Query: 238 RTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGT 297
            T L+  S++      A+T V S+T  +P TT    +   PGL    QG  + F +    
Sbjct: 576 HTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGL----QGESTAFQTH--- 627

Query: 298 PDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAAT 357
           P +T  + +P S   APV     +H  P   P+      + T G S   ST       A+
Sbjct: 628 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSPDAS 686

Query: 358 GPTPAAFDTSVSAPSQG----IPQGA---STTPQAPTHPSRVSESTI----SGAKEETVA 406
           G TP++  ++ S   +     I  G+   +T P + T P     ST       +   T++
Sbjct: 687 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 746

Query: 407 TLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATI 462
             +MT       ST   +  G+  + + PA T  PG +   + V    +     T+
Sbjct: 747 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 802



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 108/438 (24%), Positives = 163/438 (37%), Gaps = 62/438 (14%)

Query: 48  GTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATV--- 104
           G   T  HS    T   +L   PD   +      + P   +   P T T+S   +T    
Sbjct: 204 GPEYTTFHSRPGSTETTLL---PDNTTASGLLEASMPVHSSTRSPHT-TLSPAGSTTRQG 259

Query: 105 --TAPHS-ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
             T  HS  SS  T PAP    TTS+  E       +P+ + T    A S  +     +T
Sbjct: 260 ESTTFHSWPSSKDTRPAPPT--TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 317

Query: 162 TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN---------PSSTPLGQKRP 212
           T      PGS++      +   P +     R +E     +         PS+T    + P
Sbjct: 318 TYHSS--PGSTQ------TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 369

Query: 213 LGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLG 272
               +    G+   +  P+ ST + R+     S S Q  T     +P+ ++   T+  LG
Sbjct: 370 TS--YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT-GTIVLPARST---TSVLLG 423

Query: 273 PAKDKP---GLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD-- 327
            +   P   G        GST T+ G +  +T    +P SP     P+     G  ++  
Sbjct: 424 ESTTSPISSGSMETTALPGST-TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 482

Query: 328 ------GPSHSDSW--LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGA 379
                 G +H+ ++   T TPG SR  ST+S     +T  T     T+ S PSQ      
Sbjct: 483 TSRSRPGSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 541

Query: 380 STTPQAPTHPSRVSESTISGAKEETVA--------TLTMTDRVPSP----LSTVVSTATG 427
           S++    T  S  S + +S  +E T          T    D   S      ST V ++TG
Sbjct: 542 SSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 601

Query: 428 NFLNRLVPAGTWKPGTAG 445
           +    L PA +  PG  G
Sbjct: 602 SPRTTLSPASSTSPGLQG 619



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 87/363 (23%), Positives = 128/363 (35%), Gaps = 63/363 (17%)

Query: 40   VLPSGTPPGTMVTAPH-------SSTRHTSVVMLTPNPDGPPSQAAAPMATP-----TPR 87
            +L + TP  +   +PH       S+TR          P    +  A P  T      +  
Sbjct: 1286 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345

Query: 88   AEGHPP-THTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
            + G P  T T    A++ T   SE S +   +P A ATT S       G    +      
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1405

Query: 147  PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP 206
            PG            +T+    P  S+  G    SR        HS S        PS+T 
Sbjct: 1406 PG------------STQTMHFPESSTASGRSEESRT------SHS-STTHTISSPPSTTS 1446

Query: 207  LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAP 266
               + P    +    G+   +  PE ST + R+     +S   P T   T +P     A 
Sbjct: 1447 ALVEEPTS--YHSSPGSIATTHFPESSTTSGRSE-ESTASHSSPDTNGITPLP-----AH 1498

Query: 267  TTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQ 326
             TTS           R A+   +TF    G+ + T AS A     +A   S   +  D  
Sbjct: 1499 FTTS----------GRIAE--STTFYISPGSMETTLASTATTPGLSA--KSTILYTSDLV 1544

Query: 327  DGP-----SHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAST 381
              P     S S ++ T+ P +S   STS     + T  T  +F TS    ++ +   A  
Sbjct: 1545 GEPTTFYISPSPTYTTLFPASS---STSGLTEESTTFHTSPSF-TSTIVSTESLETLAPE 1600

Query: 382  TPQ 384
            TP+
Sbjct: 1601 TPE 1603


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 104/425 (24%), Positives = 152/425 (35%), Gaps = 50/425 (11%)

Query: 47   PGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTA 106
            P T  TA  SST  T+ ++  P      + +    ATPT      PP   ++T A T T 
Sbjct: 1892 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 1951

Query: 107  PHSESSLSTGPAPA----AMATTSSKPEGR-----PRGQAAPT---ILLTKPPGAT---- 150
              S+++ S+ P  A    A+ +T++ P        P      T   +  T  P AT    
Sbjct: 1952 TSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTA 2011

Query: 151  ---SRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPL 207
               S P TA   T         G++   A  SS P          +        PSS+P 
Sbjct: 2012 TPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG 2071

Query: 208  GQKRPLGKIFQIYKGNFTGSVEPEPS-----------TLTPRTPLWGYSSSPQPQTVAAT 256
                P   I         GS     S           T T  T   G  ++P   T  + 
Sbjct: 2072 TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG 2131

Query: 257  TVPSNTSWAPTTTSLGPA---KDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAA 313
            T PS T+ A T T+ G        PG         +T T+   T +    S A  +    
Sbjct: 2132 TPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTP 2191

Query: 314  PVP-SQRPHHG---DPQDGPSHSDSWLTVTPG------TSRPLSTSSGVFTAATG----P 359
            PVP +    HG    P    +   +W + T G       + P + +S    A TG     
Sbjct: 2192 PVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHS 2251

Query: 360  TPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET-VATLTMTDRVPSPL 418
            TPA      S+ +   P    TT   P H +  S +T +    +T  +TL  +    +P+
Sbjct: 2252 TPALSSPHPSSRTTESPPSPGTT--TPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI 2309

Query: 419  STVVS 423
            +TVV+
Sbjct: 2310 TTVVT 2314



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 120/478 (25%), Positives = 175/478 (36%), Gaps = 88/478 (18%)

Query: 47   PGTMVTAPHSSTRHTSVVML--------------------TPNPDGPPSQAAAPMATPT- 85
            P T  TA  SST  T+ ++                     TP    PP    +P  TPT 
Sbjct: 4235 PATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTA 4294

Query: 86   --PRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAA-MATTSSKPEGRPRGQAA-PTI 141
               +A       T +T+    +     ++ S  P P++ + TT + PE      A   TI
Sbjct: 4295 TSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTI 4354

Query: 142  LLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
              +  P  T   T    + TT R      +     G +           + +  G     
Sbjct: 4355 HPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTA-T 4413

Query: 202  PSSTP-----LGQKRPLGKIFQIYKGNFTGSVEP-------EPS-TLTPRTPLWGYSSSP 248
            PSSTP     L +               T S  P       EPS T T   P    +++ 
Sbjct: 4414 PSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 4473

Query: 249  QPQTVAATTVPSNTSWAPTTTSL--------GPAKDKPGLRRAA-------------QGG 287
              Q  A T   S T+  PT TS         G A   P LR  A                
Sbjct: 4474 STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSL 4533

Query: 288  GSTFT--SQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR- 344
            G+T+T  SQ  TP AT ++  P S       S          G + S +  + TPGT+  
Sbjct: 4534 GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHT 4593

Query: 345  ---PLSTSSGVFTA------ATGPTPAAFDTSVSAPSQGIP--QGASTTPQA---PTHPS 390
               P +T++G FTA       T  TP  + ++ + P+   P   G++ TP +    TH +
Sbjct: 4594 TKVPTTTTTG-FTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTA 4652

Query: 391  RV---SESTISGAKEETVATLTMTDRVPSPLSTVVS--TATGNFLNRLVPAGTWKPGT 443
            RV   + +T++     T ++ T T   P  L+T  +  TATG+  N   P+ T  PGT
Sbjct: 4653 RVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN---PSST--PGT 4705



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 100/354 (28%), Positives = 132/354 (37%), Gaps = 52/354 (14%)

Query: 45   TPPGTMVTAPHSS---TRHTSVVMLTPNPDGPPSQAAAPMATP--TPRAEGHPPTHTIST 99
            TP  TM TA  SS   T HTS V+ T       ++A   +ATP  TP         T +T
Sbjct: 3817 TPTATMSTATPSSTPETAHTSTVLTT---TATTTRATGSVATPSSTPGTAHTTKVPTTTT 3873

Query: 100  IAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPR 159
               TVT   S  +  T P   +  TT +         +  T+  +  PG T  PT     
Sbjct: 3874 TGFTVTPSSSPGTARTPPVWISTTTTPT--------TSGSTVTPSSVPGTTHTPTVLTTT 3925

Query: 160  TTT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIF 217
            TTT        P SS + +G     +  A    +         NPSSTP     P+  + 
Sbjct: 3926 TTTVATGSMATPSSSTQTSGTPPSLITTATTITATGST----TNPSSTP--GTTPIPPVL 3979

Query: 218  QIYKGNFTGSVEP--EPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAK 275
                   T +  P    ST+TP + L    + P P T A T   S +  +P T       
Sbjct: 3980 T------TTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTS 4033

Query: 276  DKPG-LRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHHGDPQDGPSHSD 333
               G L        ST TS   TP AT  +    +P  ++P PS R     P        
Sbjct: 4034 ATSGTLGTTHITEPSTGTSH--TPAATTGTTQHSTPALSSPHPSSRTTESPP-------- 4083

Query: 334  SWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPT 387
                 +PGT+ P  T++   T AT  TP+   TS   PS   P  A  T    T
Sbjct: 4084 -----SPGTTTPGHTTATSRTTATA-TPSKTRTSTLLPSS--PTSAPITTVVTT 4129



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 119/493 (24%), Positives = 173/493 (35%), Gaps = 78/493 (15%)

Query: 45   TPPGTMVTAPHSS---TRHTSVVMLT-PNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            TP  TM T   SS   T HTS V+ T        S  + P +TP     G     T  T 
Sbjct: 4346 TPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP-----GTTWILTELTT 4400

Query: 101  AATVTA---PHSESSLSTGP-------APAAMATTSSKPEGRPRGQAAPTILLTKPPGA- 149
            AAT TA   P +  S + G           A  T S+     P      T +LT+P    
Sbjct: 4401 AATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTA 4460

Query: 150  -----TSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
                 T    TA     T   P    ++      SS+  P +  G + +      R+ ++
Sbjct: 4461 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPAL--RSTAT 4518

Query: 205  TPLGQKRPLGKIFQIYKGNFTGSVEPEPS-TLTPRTPLWGYSSSPQPQTVAATTV----- 258
            TP          F     +  G+     S T TP   +   + S  P+TV  +TV     
Sbjct: 4519 TPTATS------FTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATA 4572

Query: 259  -----------------PSNTSWAPTTTSLG---PAKDKPGLRRAAQGGGSTFTSQGGTP 298
                              ++T+  PTTT+ G        PG         ST T+   T 
Sbjct: 4573 TTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTT 4632

Query: 299  DATAASGAPVSPQAAPVPSQRPH-----HGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVF 353
              T  SG+ V+P + P  +               G   + S  T T GT   L+T++   
Sbjct: 4633 PTT--SGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI 4690

Query: 354  TAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSES----TISGAKEETVATLT 409
            T ATG T     T  + P   +    +TTP A +  +  S S    T       T    T
Sbjct: 4691 T-ATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKST 4749

Query: 410  MTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRATICLSKMDI 469
             T   P P ST+ +T T       VPA T  P +  +  H +   +  H +T+  +   +
Sbjct: 4750 ATSFTPIPSSTLWTTWT-------VPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATM 4802

Query: 470  AWVILAISVPISS 482
                 + + P S+
Sbjct: 4803 TRATNSTATPSST 4815



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 99/338 (29%), Positives = 124/338 (36%), Gaps = 48/338 (14%)

Query: 45   TPPGTMVTAPHSSTR---HTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            TP  TM TA  SST    HTS V+  T    G     A P +TP          HT   +
Sbjct: 2560 TPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP-------GTAHTTKVL 2612

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
              T T   +  S S G A       S+      RG    T+  +  PG T  PT     T
Sbjct: 2613 TTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS---TVTPSSIPGTTHTPTVLTTTT 2669

Query: 161  TT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
            TT        P SS + +G    P        + +  G    NPSSTP     P+  +  
Sbjct: 2670 TTVATGSMATPSSSTQTSGT---PPSLTTTATTITATGST-TNPSSTP--GTTPIPPVLT 2723

Query: 219  IYKGNFTGSVEP--EPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKD 276
                  T +  P    ST+TP + L    + P P T A T   S +  +P T        
Sbjct: 2724 ------TTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA 2777

Query: 277  KPG-LRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHHGDPQDGPSHSDS 334
              G L        ST TS   TP AT  +    +P  ++P PS R     P  G      
Sbjct: 2778 TSGTLGTTHITEPSTGTSH--TPAATTGTTQHSTPALSSPHPSSRTTESPPSPG------ 2829

Query: 335  WLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPS 372
              T TPG +R  S      T AT  TP+   TS   PS
Sbjct: 2830 --TTTPGHTRATSR-----TTATA-TPSKTRTSTLLPS 2859



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 106/414 (25%), Positives = 150/414 (36%), Gaps = 43/414 (10%)

Query: 45   TPPGTMVTAPHSSTR---HTSVVML-TPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            TP  TM TA  SST    HTS V+  T    G     A P +TP        PT T +  
Sbjct: 4545 TPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGF 4604

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGA--TSRPTTAPP 158
             AT       SS  T   P    +T++ P       +  T+  +  PG   T+R  T   
Sbjct: 4605 TAT-----PSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTT 4659

Query: 159  RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
             T        P SS + +G    P        + +  G    NPSSTP     P+  +  
Sbjct: 4660 TTVATGSMATPSSSTQTSGT---PPSLTTTATTITATGST-TNPSSTP--GTTPITPVLT 4713

Query: 219  IYKGNFTGSVEPEPSTLTPRT----PLWGYSSSPQPQTVAATTVPSNTSW------APTT 268
                    +     S+ +PRT    P+   S++ +    + T +PS+T W      A TT
Sbjct: 4714 STATTPAATSSKATSSSSPRTATTLPVL-TSTATKSTATSFTPIPSSTLWTTWTVPAQTT 4772

Query: 269  TSLGPAKDKPGLRRAAQGGGST-FTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD 327
            T +                 ST  T+      AT ++  P S                  
Sbjct: 4773 TPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTT 4832

Query: 328  GPSHSDSWLTVTPGTSRPLSTSSGVFT--AATGPTPAAFDTSVSAPSQGIPQGASTTPQA 385
              + S + L+ TPGT+  L+  S + T    TG T  A  T           G + TP+ 
Sbjct: 4833 AATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASST----------LGTAHTPKV 4882

Query: 386  PTHPSRVSESTISGAKEETVATLTMTDRV-PSPLSTV-VSTATGNFLNRLVPAG 437
             T  + +  +T S     +    T T  V PS L T  VST + + L  L P G
Sbjct: 4883 VTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTG 4936



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 106/450 (23%), Positives = 167/450 (37%), Gaps = 65/450 (14%)

Query: 47   PGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTA 106
            P T  TA  SST  T+ ++         +      A P+      PP   +++ A T TA
Sbjct: 2978 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3037

Query: 107  PHSESSLSTGPAPA------------------------AMATTSSKPEGRPRGQAA-PTI 141
              S+++ S+ P  A                         + TT + PE      A   TI
Sbjct: 3038 TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTI 3097

Query: 142  LLTKPPGATSRPTTAPPRTTTRR-------PPRPPGSSRKGAGNSSRPVPPAPGGHSRSK 194
              +  P  T   T    + TT R       P   PG++      ++     A  G + + 
Sbjct: 3098 HPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATP 3157

Query: 195  EGQRGR----NPSSTPLGQKRPLGKIFQIYKGNFT-GSVEPEPSTLTPRTPLWGYSS-SP 248
                G        ST      P G          T G+++   ST T  T +   ++ S 
Sbjct: 3158 SSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSS 3217

Query: 249  QPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPV 308
             P T  A     +T+  PT TS+        +  ++ G   T  SQ  TP AT ++  P 
Sbjct: 3218 SPGTATALPALRSTATTPTATSV------TAIPSSSLGTAWTRLSQTTTPTATMSTATPS 3271

Query: 309  SPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR----PLSTSSGVFTAATGPTPAAF 364
            S       S            + S +  + TPGT+     P +T++G FTA    +P   
Sbjct: 3272 STPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTG-FTATPSSSPGTA 3330

Query: 365  DTS---VSAPSQGIPQGASTTPQA---PTHPSRV---SESTISGAKEETVATLTMTDRVP 415
             T    +S  +    +G++ TP +    TH + V   + +T++     T ++ T T   P
Sbjct: 3331 LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTP 3390

Query: 416  SPLSTVVS--TATGNFLNRLVPAGTWKPGT 443
              L+T  +  TATG+  N   P+ T  PGT
Sbjct: 3391 PSLTTTATTITATGSTTN---PSST--PGT 3415



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 110/428 (25%), Positives = 166/428 (38%), Gaps = 47/428 (10%)

Query: 45   TPPGTMVTAPHSST---RHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            TP  TM T   SST    HTS V+ T       ++A + M+TP+    G     T  T A
Sbjct: 3089 TPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPS-STPGTTWILTELTTA 3144

Query: 102  ATVTAPHSESSLSTGPAPAAMATTSSKPEGR-PRGQAAPTILLTKPPGATSRPTTAPPRT 160
            AT TA       +TGP     AT SS P       + + T  +T P G+T+  T +  R 
Sbjct: 3145 ATTTA-------ATGPT----ATPSSTPGTTWILTEPSTTATVTVPTGSTA--TASSTRA 3191

Query: 161  TTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIY 220
            T         ++      SSR  P +  G + +      R+ ++TP         +  I 
Sbjct: 3192 TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPAL--RSTATTPTAT-----SVTAIP 3244

Query: 221  KGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTV-PSNTSWAPTTTSLGPAKDKPG 279
              +   +      T TP   +   + S  P+TV  +TV  + T+    T S+      PG
Sbjct: 3245 SSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPG 3304

Query: 280  LRRAAQGGGSTFTSQGGTPDAT--AASGAPVSPQAAPVPSQRPHHGDPQD--GPSHSDSW 335
                 +   +T T    TP ++   A   PV       P+ R     P    G +H+ + 
Sbjct: 3305 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 3364

Query: 336  LTVTPGT--SRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTP-QAPTHPSRV 392
            LT T  T  +  ++T S   T  +G  P+   T+ +  + G     S+TP   P  P   
Sbjct: 3365 LTTTTTTVATGSMATPSS-STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT 3423

Query: 393  SESTISGAKEETV---ATLTMTDRVPSPLSTVVSTATGNFLNRLVP---AGTWKPGTAG- 445
            + +T   A   TV   + L  T   P P +T  +T  G  L    P      W   T+G 
Sbjct: 3424 TTATTPAATSSTVTPSSALGTTHTPPVPNTT--ATTHGRSLPPSSPHTVRTAWTSATSGI 3481

Query: 446  -NISHVAE 452
               +H+ E
Sbjct: 3482 LGTTHITE 3489



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 93/354 (26%), Positives = 131/354 (37%), Gaps = 49/354 (13%)

Query: 32   PSPRESL-----QVLPSGTPPGTMVTAPHSS---TRHTSVVM-LTPNPDGPPSQAAAPMA 82
            P P  SL     ++  + TP  TM TA  SS   T HTS V+  T    G     A P +
Sbjct: 1985 PIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2044

Query: 83   TPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTIL 142
            TP        PT T +   AT       SS  T   P    +T++ P  R       T+ 
Sbjct: 2045 TPGTAHTTKVPTTTTTGFTAT-----PSSSPGTALTPPVWISTTTTPTTR-----GSTVT 2094

Query: 143  LTKPPGATSRPTTAPPRTTT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGR 200
             +  PG T   T     TTT        P SS + +G    P        + +  G    
Sbjct: 2095 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT---PPSLTTTATTITATGST-T 2150

Query: 201  NPSSTPLGQKRPLGKIFQIYKGNFTGSVEP--EPSTLTPRTPLWGYSSSPQPQTVAATTV 258
            NPSSTP     P+  +        T +  P    +T+TP + L    + P P T+A T  
Sbjct: 2151 NPSSTP--GTTPIPPVLT------TTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHG 2202

Query: 259  PSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQ 318
             S    +P T          G+       G+T  ++  T  +   +    + Q +     
Sbjct: 2203 RSLPPSSPHTVRTAWTSATSGIL------GTTHITEPSTVTSHTLAATTGTTQHSTPALS 2256

Query: 319  RPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPS 372
             PH       PS   +    +PGT+ P  T++   T AT  TP+   TS   PS
Sbjct: 2257 SPH-------PSSRTTESPPSPGTTTPGHTTATSRTTATA-TPSKTRTSTLLPS 2302



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 109/460 (23%), Positives = 160/460 (34%), Gaps = 75/460 (16%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGH 91
            +P  S    PS TP  T +    ++T  T+     T  P   P      +  P+  A   
Sbjct: 3677 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWI-LTEPSTTATVT 3735

Query: 92   PPTH---TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT-KPP 147
             PT    T S+  AT   PH  ++ +T    ++ AT  S P       A P +  T   P
Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP---GTATALPALRSTATTP 3792

Query: 148  GATS----------------RPTTAPPRT-TTRRPPRPP------------GSSRKGAGN 178
             ATS                  TT P  T +T  P   P             ++ +  G+
Sbjct: 3793 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852

Query: 179  SSRPVPPAPGGHSRSKEGQRGR-----NPSSTPLGQKRPLGKIFQIYKGNFTGSV----- 228
             + P    PG    +K            PSS+P   + P   I        +GS      
Sbjct: 3853 VATP-SSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSS 3911

Query: 229  ------EPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPA---KDKPG 279
                   P   T T  T   G  ++P   T  + T PS  + A T T+ G        PG
Sbjct: 3912 VPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPG 3971

Query: 280  LRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVP-SQRPHHG---DPQDGPSHSDSW 335
                     +T T+   T      S A  +    PVP +    HG    P    +   +W
Sbjct: 3972 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAW 4031

Query: 336  LTVTPGT------SRPLSTSSGVFTAATG----PTPAAFDTSVSAPSQGIPQGASTTPQA 385
             + T GT      + P + +S    A TG     TPA      S+ +   P    TT   
Sbjct: 4032 TSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT--T 4089

Query: 386  PTHPSRVSESTISGAKEET-VATLTMTDRVPSPLSTVVST 424
            P H +  S +T +    +T  +TL  +    +P++TVV+T
Sbjct: 4090 PGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4129



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 110/459 (23%), Positives = 160/459 (34%), Gaps = 75/459 (16%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGH 91
            +P  S   +PS TP  T +    ++T  T+     T  P   P      +  P+  A   
Sbjct: 2420 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWI-LTEPSTTATVT 2478

Query: 92   PPTH---TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT-KPP 147
             PT    T S+  AT   PH  ++ +T    ++ AT  S P       A P +  T   P
Sbjct: 2479 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP---GTATALPALRSTATTP 2535

Query: 148  GATS----------------RPTTAPPRT-TTRRPPRPP-----------GSSRKGAGNS 179
             ATS                  TT P  T +T  P   P            ++  GA  S
Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGS 2595

Query: 180  SRPVPPAPGGHSRSK-----EGQRGRNPSSTPLGQKR-----------PLGKIFQIYKGN 223
                   PG    +K            PSS+P G  R           P  +   +   +
Sbjct: 2596 VATPSSTPGTAHTTKVLTTTTTGFTATPSSSP-GTARTLPVWISTTTTPTTRGSTVTPSS 2654

Query: 224  FTGSVE-PEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPA---KDKPG 279
              G+   P   T T  T   G  ++P   T  + T PS T+ A T T+ G        PG
Sbjct: 2655 IPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG 2714

Query: 280  LRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVP-SQRPHHG---DPQDGPSHSDSW 335
                     +T T+   T      S A  +    PVP +    HG    P    +   +W
Sbjct: 2715 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAW 2774

Query: 336  LTVTPGT------SRPLSTSSGVFTAATG----PTPAAFDTSVSAPSQGIPQGASTTPQA 385
             + T GT      + P + +S    A TG     TPA      S+ +   P    TT   
Sbjct: 2775 TSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT--T 2832

Query: 386  PTHPSRVSESTISGAKEET-VATLTMTDRVPSPLSTVVS 423
            P H    S +T +    +T  +TL  +    +P++TVV+
Sbjct: 2833 PGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 2871



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 117/513 (22%), Positives = 172/513 (33%), Gaps = 123/513 (23%)

Query: 33   SPRESLQVLPSGTPPG-----TMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
            +P  S Q   SGTPP      T +TA  S+T  +S    TP P    + A  P AT    
Sbjct: 2679 TPSSSTQT--SGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT---- 2732

Query: 88   AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
                         ++TVT   +  +  T P P   ATT     GR    ++P  + T   
Sbjct: 2733 -------------SSTVTPSSALGTTHTPPVPNTTATT----HGRSLSPSSPHTVRTAWT 2775

Query: 148  GATSRPT-----TAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP 202
             ATS        T P   T+  P    G+++      S P       H  S+  +   +P
Sbjct: 2776 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP-------HPSSRTTESPPSP 2828

Query: 203  SSTPLGQKRPLGKIFQIYKGNFTGSVEPEP---STLTPRTPLWGYSSSPQPQTVAATTVP 259
             +T  G  R   +         T +  P     STL P +P     +S    TV      
Sbjct: 2829 GTTTPGHTRATSRT--------TATATPSKTRTSTLLPSSP-----TSAPITTVVTMGCE 2875

Query: 260  SNTSWA-------PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPV---- 308
               +W+       P     G   D     RAA GG       G    A A  G P+    
Sbjct: 2876 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLRELG 2934

Query: 309  -----SPQAAPVPSQRPHHGD-------------------PQDGPSHSDSWLTVTPGTSR 344
                 S     V   R   G                    P    + S +  + TPGT+ 
Sbjct: 2935 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTW 2994

Query: 345  PLS--TSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKE 402
             L+  T++   TA TG T     T  +AP   +    +TTP A +               
Sbjct: 2995 ILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS--------------- 3039

Query: 403  ETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNIS-------------H 449
             + AT + + R  + L  + STAT +      P  ++  GT G +              H
Sbjct: 3040 -SKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIH 3098

Query: 450  VAEGDKPQHRATICLSKMDIAWVILAISVPISS 482
             +   +  H +T+  +K        ++S P S+
Sbjct: 3099 PSSTPETTHTSTVLTTKATTTRATSSMSTPSST 3131



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 115/513 (22%), Positives = 173/513 (33%), Gaps = 123/513 (23%)

Query: 33   SPRESLQVLPSGTPPG-----TMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
            +P  S Q   SGTPP      T +TA  S+T  +S    TP P    + A  P AT    
Sbjct: 3936 TPSSSTQT--SGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT---- 3989

Query: 88   AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
                         ++TVT   +  +  T P P   ATT     GR    ++P  + T   
Sbjct: 3990 -------------SSTVTPSSALGTTHTPPVPNTTATT----HGRSLSPSSPHTVRTAWT 4032

Query: 148  GATSRPT-----TAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP 202
             ATS        T P   T+  P    G+++      S P       H  S+  +   +P
Sbjct: 4033 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP-------HPSSRTTESPPSP 4085

Query: 203  SSTPLGQKRPLGKIFQIYKGNFTGSVEPEP---STLTPRTPLWGYSSSPQPQTVAATTVP 259
             +T  G      +         T +  P     STL P +P     +S    TV  T   
Sbjct: 4086 GTTTPGHTTATSRT--------TATATPSKTRTSTLLPSSP-----TSAPITTVVTTGCE 4132

Query: 260  SNTSWA-------PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQA 312
               +W+       P     G   D     RAA GG       G    A A  G P+    
Sbjct: 4133 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPGVPLGELG 4191

Query: 313  APVPSQRP---------------------------HHGDPQDGPSHSDSWL-TVTPGTSR 344
              V                                ++G     P+ S + + + TPGT+ 
Sbjct: 4192 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTW 4251

Query: 345  PLS--TSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKE 402
             L+  T++   TA+TG T     T  +AP   +    +TTP A +               
Sbjct: 4252 ILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATS--------------- 4296

Query: 403  ETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNIS-------------H 449
             + AT + + R  + L  + STAT +    + P  +   GT G +              H
Sbjct: 4297 -SKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIH 4355

Query: 450  VAEGDKPQHRATICLSKMDIAWVILAISVPISS 482
             +   +  H +T+  +K        + S P S+
Sbjct: 4356 PSSTPETTHTSTVLTTKATTTRATSSTSTPSST 4388



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 77/304 (25%), Positives = 112/304 (36%), Gaps = 59/304 (19%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATP--TPRAEGHPP--THTISTI 100
            T   T+  +    T HT+ V+ T       + A   MATP  + +  G PP  T T +TI
Sbjct: 3345 TRGSTVTPSSIPGTTHTATVLTTTT----TTVATGSMATPSSSTQTSGTPPSLTTTATTI 3400

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
             AT +  +  S+  T P P  + TT+                 T P   +S  T +    
Sbjct: 3401 TATGSTTNPSSTPGTTPIPPVLTTTA-----------------TTPAATSSTVTPSSALG 3443

Query: 161  TTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIY 220
            TT  PP P       A    R +PP+      S    R    S+T               
Sbjct: 3444 TTHTPPVP----NTTATTHGRSLPPS------SPHTVRTAWTSAT--------------- 3478

Query: 221  KGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGL 280
             G    +   EPST+T  TP    S++       ++  PS+ +   T +   P    PG 
Sbjct: 3479 SGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRT---TESPPSPGTTTPGH 3535

Query: 281  RRAAQGGGSTFTSQGGTPDATAASG-APVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVT 339
             R     G++ T+   TP  T  S   P SP +AP+ +      +PQ   S    +    
Sbjct: 3536 TR-----GTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPM 3590

Query: 340  PGTS 343
            PG S
Sbjct: 3591 PGPS 3594



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 60/240 (25%), Positives = 94/240 (39%), Gaps = 31/240 (12%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATP--TPRAEGHPP--THTISTI 100
            T   T+  +    T HT+ V+ T       + A   MATP  + +  G PP  T T +TI
Sbjct: 2088 TRGSTVTPSSIPGTTHTATVLTTTT----TTVATGSMATPSSSTQTSGTPPSLTTTATTI 2143

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
             AT +  +  S+  T P P  + TT++ P        + T+  +   G T  P       
Sbjct: 2144 TATGSTTNPSSTPGTTPIPPVLTTTATTP-----AATSNTVTPSSALGTTHTPPVPNTMA 2198

Query: 161  TTRRPPRPPG----------SSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP-LGQ 209
            TT     PP           S+  G   ++    P+    S +     G    STP L  
Sbjct: 2199 TTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-VTSHTLAATTGTTQHSTPALSS 2257

Query: 210  KRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTT 269
              P  +  +       G+  P  +T T RT     +++   +T  +T +PS+ + AP TT
Sbjct: 2258 PHPSSRTTE--SPPSPGTTTPGHTTATSRTT----ATATPSKTRTSTLLPSSPTSAPITT 2311



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 90/398 (22%), Positives = 138/398 (34%), Gaps = 48/398 (12%)

Query: 94   THTISTIAATVTAPHSESS----LSTGPAPAAMATTSSKPEGRPRG--QAAP-----TIL 142
            +H  ST A + TA  S +     + T P   A  T S+     P    + AP     T  
Sbjct: 1886 SHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTT 1945

Query: 143  LTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ----- 197
             T P   +S+ T +    T    P    ++      S  P+P +  G + ++  Q     
Sbjct: 1946 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2005

Query: 198  ---RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS-------TLTPRTPLWGYSSS 247
                   PSSTP                  TGSV    S       T  P T   G++++
Sbjct: 2006 ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT 2065

Query: 248  PQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAP 307
            P      A T P    W  TTT+  P      +  ++  G +   +   T   T A+G+ 
Sbjct: 2066 PSSSPGTALTPP---VWISTTTT--PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSM 2120

Query: 308  VSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGV----FTAATGPTPAA 363
             +P ++   S  P         + + + +T T  T+ P ST            T  TPAA
Sbjct: 2121 ATPSSSTQTSGTP------PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAA 2174

Query: 364  FDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVS 423
               +V+ PS  +  G + TP  P   +     ++  +   TV T   T      L T   
Sbjct: 2175 TSNTVT-PSSAL--GTTHTPPVPNTMATTHGRSLPPSSPHTVRT-AWTSATSGILGTTHI 2230

Query: 424  TATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQHRAT 461
            T      +  + A T   GT  + +       P  R T
Sbjct: 2231 TEPSTVTSHTLAATT---GTTQHSTPALSSPHPSSRTT 2265



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 87/369 (23%), Positives = 130/369 (35%), Gaps = 41/369 (11%)

Query: 78   AAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQA 137
            + P  + T      P T  I T   T TA  +ES+ ST    +   TT    E       
Sbjct: 2419 STPATSSTAMPSSTPGTTWILT-ELTTTATTTESTGSTATPSSTPGTTWILTE------P 2471

Query: 138  APTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ 197
            + T  +T P G+T+   TA     T   P    ++      SS+  P +  G + +    
Sbjct: 2472 STTATVTVPTGSTA---TASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPAL 2528

Query: 198  RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS-TLTPRTPLWGYSSSPQPQTVAAT 256
            R  + ++TP          F     +  G+     S T TP   +   + S  P+TV  +
Sbjct: 2529 R--STATTPTATS------FTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS 2580

Query: 257  TVPSNTSWAPTTT-SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDAT--AASGAPVSPQAA 313
            TV + T+     T S+      PG     +   +T T    TP ++   A   PV     
Sbjct: 2581 TVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTT 2640

Query: 314  PVPSQRPHHGDPQD--GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAP 371
              P+ R     P    G +H+ + LT T              T ATG        S S  
Sbjct: 2641 TTPTTRGSTVTPSSIPGTTHTPTVLTTT------------TTTVATGSMATP---SSSTQ 2685

Query: 372  SQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVV--STATGNF 429
            + G P   +TT    T     +  + +         LT T   P+  S+ V  S+A G  
Sbjct: 2686 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 2745

Query: 430  LNRLVPAGT 438
                VP  T
Sbjct: 2746 HTPPVPNTT 2754



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 69/252 (27%), Positives = 99/252 (39%), Gaps = 45/252 (17%)

Query: 231  EPSTL-TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL--------GPAKDKPGLR 281
            EPST  T   P    +++   Q  A T   S T+  PT TS         G A   P LR
Sbjct: 3727 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 3786

Query: 282  RAA-------------QGGGSTFT--SQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQ 326
              A                G+T+T  SQ  TP AT ++  P S       S         
Sbjct: 3787 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATT 3846

Query: 327  DGPSHSDSWLTVTPGTSR----PLSTSSGVFTAATGPTPAAFDTS---VSAPSQGIPQGA 379
               + S +  + TPGT+     P +T++G FT     +P    T    +S  +     G+
Sbjct: 3847 TRATGSVATPSSTPGTAHTTKVPTTTTTG-FTVTPSSSPGTARTPPVWISTTTTPTTSGS 3905

Query: 380  STTPQA---PTHPSRV---SESTISGAKEETVATLTMTDRVPSPLSTVVS--TATGNFLN 431
            + TP +    TH   V   + +T++     T ++ T T   P  L T  +  TATG+  N
Sbjct: 3906 TVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTN 3965

Query: 432  RLVPAGTWKPGT 443
               P+ T  PGT
Sbjct: 3966 ---PSST--PGT 3972



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 51/182 (28%), Positives = 69/182 (37%), Gaps = 45/182 (24%)

Query: 33   SPRESLQVLPSGTPPG-----TMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
            +P  S Q   SGTPP      T +TA  S+T  +S    TP P    + A  P AT    
Sbjct: 3379 TPSSSTQT--SGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT---- 3432

Query: 88   AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
                         ++TVT   +  +  T P P   ATT     GR    ++P  + T   
Sbjct: 3433 -------------SSTVTPSSALGTTHTPPVPNTTATT----HGRSLPPSSPHTVRTAWT 3475

Query: 148  GATS---------RPTT----APPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPG----GH 190
             ATS          P+T     P  TT+      P  S     + +   PP+PG    GH
Sbjct: 3476 SATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 3535

Query: 191  SR 192
            +R
Sbjct: 3536 TR 3537



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 116/547 (21%), Positives = 183/547 (33%), Gaps = 140/547 (25%)

Query: 22   TEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPM 81
            T+AL    Q  S     +  P+ T     ++   +S R+TS +  T    GP        
Sbjct: 1627 TQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG-TATTGGP-------- 1677

Query: 82   ATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGP-------APAAMATTSSKPEGRPR 134
             TP    E   P    ST+      P +  SL T         AP  MAT+ ++P G   
Sbjct: 1678 TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAS 1737

Query: 135  GQAAPTILLTKPPG-----ATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSR-------- 181
              +   +  +  P      +TS+  T+ PRT T   P    ++ +G              
Sbjct: 1738 TASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWF 1797

Query: 182  ----PVPPAPGGHSRSKEGQRGRN------PSSTPLGQKR----PLGKIFQIYKGNFTGS 227
                P     GG   + E  R         P S     +      + ++ Q+   +    
Sbjct: 1798 DVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETG 1857

Query: 228  VEPEPSTLTPRTPLW-----------GYSSSPQPQTVAATTVPSN---TSW--------A 265
            +  +    T R  +             YS  P     ++T  PS+   T+W        A
Sbjct: 1858 LTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTA 1917

Query: 266  PTTTSLGPAKDKPGLRRAA--------QGGGSTFTSQGGTPDAT-----------AASGA 306
             TT S G         R A             T TS   TP ++           + +  
Sbjct: 1918 TTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATT 1977

Query: 307  PVSPQAAPVPSQ-----------------RPHHGDPQDGP--SHSDSWLTV--------- 338
            P +    P+PS                        P   P  +H+ + LT          
Sbjct: 1978 PTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATG 2037

Query: 339  -------TPGTSR----PLSTSSGVFTAATGPTPAAFDTS---VSAPSQGIPQGASTTPQ 384
                   TPGT+     P +T++G FTA    +P    T    +S  +    +G++ TP 
Sbjct: 2038 SVATPSSTPGTAHTTKVPTTTTTG-FTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPS 2096

Query: 385  A---PTHPSRV---SESTISGAKEETVATLTMTDRVPSPLSTVVS--TATGNFLNRLVPA 436
            +    TH + V   + +T++     T ++ T T   P  L+T  +  TATG+  N   P+
Sbjct: 2097 SIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN---PS 2153

Query: 437  GTWKPGT 443
             T  PGT
Sbjct: 2154 ST--PGT 2158



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 59/234 (25%), Positives = 88/234 (37%), Gaps = 56/234 (23%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATV 104
            TPP T      ++T  T  +  TP P   P    AP A+ T           + T++  +
Sbjct: 1612 TPPPT-TELETATTTTTQALFSTPQPTSSPGLTRAPPASTT----------AVPTLSEGL 1660

Query: 105  TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRR 164
            T+P   S+L T       ATT       P G   PT+     PG  +  +T P R+    
Sbjct: 1661 TSPRYTSTLGT-------ATTGGPT--TPAGSTEPTV-----PGVAT--STLPTRSAL-- 1702

Query: 165  PPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNF 224
                PG++  G+  + RP  P                P++    + RP G          
Sbjct: 1703 ----PGTT--GSLGTWRPSQPPT------------LAPTTMATSRARPTGTA-------S 1737

Query: 225  TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP 278
            T S EP  ++L P   L    S+ Q +T    T  + +    TTTS G  + +P
Sbjct: 1738 TASKEPLTTSLAP--TLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQP 1789



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 59/248 (23%), Positives = 91/248 (36%), Gaps = 19/248 (7%)

Query: 33   SPRESLQVLPSGTPPG-----TMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
            +P  S Q   SGTPP      T +TA  S+T  +S    TP      S A  P AT +  
Sbjct: 4669 TPSSSTQT--SGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKA 4726

Query: 88   AEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
                 P    +    T TA  S ++  T    + + TT + P       +  + + T   
Sbjct: 4727 TSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSST 4786

Query: 148  GATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTP- 206
              T+  +T    T T        ++      ++R +       + +         SSTP 
Sbjct: 4787 PETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPG 4846

Query: 207  ----LGQKRPLGKIFQIYKGNFTGSVEPEPSTL-TPRTPLWGYSSSPQPQTVAATTVPSN 261
                L +   +  +        TGS     STL T  TP    + +  P T  A+TVPS+
Sbjct: 4847 TTWILTEPSTIATVMVP-----TGSTATASSTLGTAHTPKVVTTMATMP-TATASTVPSS 4900

Query: 262  TSWAPTTT 269
            ++   T T
Sbjct: 4901 STVGTTRT 4908


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 102/412 (24%), Positives = 144/412 (34%), Gaps = 73/412 (17%)

Query: 32  PSPRESLQVLPS--GTPPGTMVTAPHSSTRHTSVVML---------TPNPDGPPSQAA-- 78
           PS   SLQ LPS   TPP    T+  S T   +   L         TP P  PP+ A   
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365

Query: 79  -------------APMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATT 125
                        +P+ATP+P+A      H +    +   +P  ++  S  PA   ++ +
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPS 424

Query: 126 SSKPEGRPRGQAAPTILL-------------TKPPGATSRPTTAPPRTTTRRPPRPPGSS 172
           ++ P   P   AAP + +               PP     P  APP    + PP+ P  +
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PA 483

Query: 173 RKGAGNSSRPVPPA--PGGHSRSKEGQRGRNPSSTPLGQKRPL--GKIFQIYKGNFTGSV 228
                  + P PPA  PG    S       +P +TP  Q  P+    + Q+       S 
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-----PPSP 538

Query: 229 EPEPSTLTPRTPLW----GYSSSPQPQTVAATTVPSNTSWAPTTTSLGP--------AKD 276
              P+   PR P         S P+     A   P   S +P++T  GP        A  
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 598

Query: 277 KPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVP-------SQRPHHGDPQDGP 329
            P   R    G     +    PDA  A+  P +    P P          P    P  GP
Sbjct: 599 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 658

Query: 330 SHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAST 381
             +D   T+   T  P S +        GP+P    TS    + G   GAS+
Sbjct: 659 GSADGLCTIYE-TEGPESATPAPGALDPGPSPG---TSGGKAAAGAGAGASS 706



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 99/366 (27%), Positives = 126/366 (34%), Gaps = 47/366 (12%)

Query: 65  MLTPNPDG-----PPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAP 119
           +LTP P G     PP   AA        A G  P    +      T P S        AP
Sbjct: 24  LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES--------AP 75

Query: 120 AAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNS 179
            A  T +S+P    RG+ AP    T P      P ++P R +    P P G  +KG   S
Sbjct: 76  RAGPTRTSRPPASGRGERAPPAKNTSP-----GPVSSPGRASGTTRPGPLG--QKGLRIS 128

Query: 180 SRPV---PPAPGGHSRSKEGQRGRNPSSTPL-GQKRPLGKIFQIYKGNFTGSVEPEPSTL 235
           +        A     RS      R  +S P  G   P         G   G   P PS  
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA- 187

Query: 236 TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQG 295
            PR P  G   S    +  +TT PS    A    S G    +P  R  +       +   
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPA--ARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245

Query: 296 GTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTA 355
             P A     AP  P + P P        PQ  P   D+   + P +S PL+T       
Sbjct: 246 SGPSARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT------- 297

Query: 356 ATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVP 415
              P+P+A       PS   P    T P  P  P   S++T S       AT +     P
Sbjct: 298 ---PSPSA------PPSPSAPPSLQTLPSPPATPP--SQATTSLGSPTLQATHSFLPSPP 346

Query: 416 -SPLST 420
            SPL+T
Sbjct: 347 LSPLAT 352



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 95/375 (25%), Positives = 124/375 (33%), Gaps = 56/375 (14%)

Query: 31  EPSPRESLQVLPSGTPPGTMVTAP-----HSSTRHTSVVMLTPNPDGPPSQAAAPMATPT 85
           +P P+    + P    P     AP      SS   T      P+P  PPS    P    T
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321

Query: 86  PRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTK 145
           P     P   T S  + T+ A HS       P+P      +  P+  P     P   L  
Sbjct: 322 P-----PSQATTSLGSPTLQATHSFL-----PSPPLSPLATPPPQAPPALALPP---LQA 368

Query: 146 PPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST 205
           PP   + P  +P  T + + P         A  S  P PP       S       +PS+T
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPVSPSAT 426

Query: 206 PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWA 265
           P  Q  P      +        V P P    P +P    S++P PQ       P      
Sbjct: 427 PPSQAPPSLAAPPL-------QVPPSPPASPPMSP----SATPPPQAPPPLAAP------ 469

Query: 266 PTTTSLGPAKDKPGLRR-AAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGD 324
           P   +  P +  P L     Q   S   S  G    + ++  P+SP A P P   P    
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529

Query: 325 PQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQ 384
           P          L   P    P   +S    A   P     DTSVS P   +    +  P 
Sbjct: 530 P----------LLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTL----ALAPG 571

Query: 385 APTHPSRVSESTISG 399
            P  PSR   ST+SG
Sbjct: 572 PPPPPSRSPSSTLSG 586



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 93/376 (24%), Positives = 124/376 (32%), Gaps = 51/376 (13%)

Query: 43  SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           SG  PGT   A    +R     +  P P        AP A P P  EG  P  ++S+ + 
Sbjct: 156 SGPTPGTPSPAMARRSRAAGTEVGLPRP--------APSARPRPPTEG--PRKSVSSASE 205

Query: 103 TVTAPHSES-----------------SLSTGPAP-AAMATTSSKPEGRPRGQAAPTILLT 144
             T   S +                 SLS+   P ++ A +     G PR  A P+    
Sbjct: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS--QP 263

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
           KP G  +     PP+ T  R    P      +   + P P AP   S     Q   +P +
Sbjct: 264 KPKGLQA---LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320

Query: 205 TPLGQ-KRPLGKIFQIYKGNFTGSVEPEPSTLTP--------RTPLWGYSSSPQPQTVAA 255
           TP  Q    LG        +F  S    P    P          PL    S P    ++ 
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380

Query: 256 TTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPV 315
              PS  +       L  A   P      Q   S   S   +P AT  S AP S  A P+
Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440

Query: 316 PSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGI 375
                    P   PS +       P  + PL  +         P P A     + P Q +
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK--------PPPQAPPALATPPLQAL 492

Query: 376 PQGASTTP-QAPTHPS 390
           P   ++ P QAP  PS
Sbjct: 493 PSPPASFPGQAPFSPS 508



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 51/196 (26%), Positives = 67/196 (34%), Gaps = 42/196 (21%)

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
           P  LTPR P  G    P P T AA  V           + G    KP   RA   GG+T 
Sbjct: 22  PGLLTPRPP--GSPRPPPPVTPAALRVLG---------AAGAVGRKPLAERAGGIGGATI 70

Query: 292 TSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPG---------- 341
                    T  S  P S +    P  +     P   P  +    T  PG          
Sbjct: 71  PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG--TTRPGPLGQKGLRIS 128

Query: 342 ----------TSRP--LSTSSGVFTAATGPTPAAFDTSVSAPSQ------GIPQGA-STT 382
                     T  P   + S+G     +GPTP     +++  S+      G+P+ A S  
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188

Query: 383 PQAPTHPSRVSESTIS 398
           P+ PT   R S S+ S
Sbjct: 189 PRPPTEGPRKSVSSAS 204


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 95/392 (24%), Positives = 148/392 (37%), Gaps = 39/392 (9%)

Query: 47   PGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTA 106
            P T  TA  SST  T+ ++  P      + +    ATPT      PP   ++T A T T 
Sbjct: 2582 PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTV 2641

Query: 107  PHSESSLSTGPAPA----AMATTSSKPEGRPRGQAAPTILLTKPPGAT----SRPTTAPP 158
              S+++ S+ P  A    A+ +T++ P        + T + +   G T    S+ TT   
Sbjct: 2642 TSSKATPSSSPGTATALPALRSTATTPTA-----TSVTPIPSSSLGTTWTRLSQTTTPTA 2696

Query: 159  RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
              +T  P   P ++      ++        G   +        PSSTP        K+  
Sbjct: 2697 TMSTATPSSTPETAHTSTVLTATATTTGATGSVAT--------PSSTP--GTAHTTKVPT 2746

Query: 219  IYKGNFTGSVEPEPST-LTPRTPLWGYSSSPQPQTVAATTVPSN-TSWAPTTTSLGPAKD 276
                 FT +    P T LTP  P+W  S++  P T  +T  PS+      T T L     
Sbjct: 2747 TTTTGFTATPSSSPGTALTP--PVW-ISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 2803

Query: 277  KPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWL 336
                   A    ST TS  GT           +     +P   PH    +   + + S +
Sbjct: 2804 TVATGSMATPSSSTQTS--GTTHTPPVPNTMATTHGRSLPPSSPH--TVRTAWTSATSGI 2859

Query: 337  TVTPGTSRPLSTSSGVFTAATG----PTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRV 392
              T   + P + +S    A TG     TPA      S+ +   P    TT   P H +  
Sbjct: 2860 LGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT--TPGHTTAT 2917

Query: 393  SESTISGAKEET-VATLTMTDRVPSPLSTVVS 423
            S +T +    +T  +TL  +    +P++TVV+
Sbjct: 2918 SRTTATATPSKTRTSTLLPSSPTSAPITTVVT 2949



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 107/484 (22%), Positives = 163/484 (33%), Gaps = 80/484 (16%)

Query: 33   SPRESLQVLPSGTPPGTMV-------TAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPT 85
            +P  S   +PS TP  T +           +ST  T+    TP    PP    +P  TPT
Sbjct: 4704 TPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPT 4763

Query: 86   P---RAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAA-MATTSSKPEGRPRGQAA-PT 140
                +A       T +T+    +     ++ S  P P++ + TT + PE      A   T
Sbjct: 4764 ATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMST 4823

Query: 141  ILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGR 200
            I  +  P  T   T    + TT R      +     G +           + +  G    
Sbjct: 4824 IHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTA- 4882

Query: 201  NPSSTP-----LGQKRPLGKIFQIYKGNFTGSVEP-------EPSTL-TPRTPLWGYSSS 247
             PSSTP     L +               T S  P       EPST  T   P    +++
Sbjct: 4883 TPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATA 4942

Query: 248  PQPQTVAATTVPSNTSWAPTTTSL--------GPAKDKPGLRRAA-------------QG 286
               Q  A T   S T+  PT TS         G A   P LR  A               
Sbjct: 4943 SSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSS 5002

Query: 287  GGSTFT--SQGGTPDATAASGAPVSPQ--------------------AAPVPSQRPHHGD 324
             G+T+T  SQ  TP AT ++  P S                      +   PS  P    
Sbjct: 5003 LGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAH 5062

Query: 325  PQDGPSHSDSWLTVTPG----------TSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
                P+ + +  T TP           T+ P+ST S + T++T  T        +  +  
Sbjct: 5063 TTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMT 5122

Query: 375  IPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLV 434
                ++ TP +    +R+  + ++     T AT +      +P +T + T        +V
Sbjct: 5123 RATNSTATPSSTLGTTRIL-TELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMV 5181

Query: 435  PAGT 438
            P G+
Sbjct: 5182 PTGS 5185



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 104/439 (23%), Positives = 153/439 (34%), Gaps = 69/439 (15%)

Query: 45   TPPGTMVTAPHSST---RHTSVVMLTPNPDGPPSQAAAPMATP----------------- 84
            TP  TM T   SST    HTS V+ T       ++A + M+TP                 
Sbjct: 3669 TPMATMSTIHPSSTPETTHTSTVLTTK---ATTTRATSSMSTPSSTPGTTWILTELTTAA 3725

Query: 85   -TPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILL 143
             T  A G  PT T S+   T       S+ +T   P     T+S            T   
Sbjct: 3726 TTTAATG--PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTA 3783

Query: 144  TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ------ 197
            T P   +SR T +    T    P    ++      S   +P +  G + ++  Q      
Sbjct: 3784 TTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTA 3843

Query: 198  --RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPS-------TLTPRTPLWGYSSSP 248
                  PSSTP                  TGSV    S       T  P T   G++++P
Sbjct: 3844 TMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 3903

Query: 249  QPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPV 308
                  A T P    W  TTT+  P      +  ++  G +   +   T   T A+G+  
Sbjct: 3904 SSSPGTALTPP---VWISTTTT--PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMA 3958

Query: 309  SPQAAPVPSQRPHHGDPQD--GPSHSDSWLTVTPGTSRPLSTS--SGVF--------TAA 356
            +P ++   S   H     +    +H  S    +P T R   TS  SG+         +  
Sbjct: 3959 TPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTV 4018

Query: 357  TGPTPAA--FDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET---------V 405
            T  TPAA    T  S P+   P  +S T ++P  P   +     G    T          
Sbjct: 4019 TSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT 4078

Query: 406  ATLTMTDRVPSPLSTVVST 424
            +TL  +    +P++TVV+T
Sbjct: 4079 STLLPSSPTSAPITTVVTT 4097



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 110/424 (25%), Positives = 164/424 (38%), Gaps = 58/424 (13%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGH 91
            +P  S    PS TP  T +    ++T  T+     T  P   P      +  P+  A   
Sbjct: 4202 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWI-LTEPSTTATVT 4260

Query: 92   PPTH---TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPG 148
             PT    T S+  AT   PH  ++ +T    ++ AT  S P G      A     T P  
Sbjct: 4261 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP-GTATALPALRSTATTPTA 4319

Query: 149  A--TSRPTTAPPRTTTR-RPPRPPGSSRKGAGNSSRPVPPAPG-----GHSRSKEGQRGR 200
               T+ P+++   T TR      P ++   A  SS P             + ++      
Sbjct: 4320 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVA 4379

Query: 201  NPSSTPLGQKRPLGKIFQIYKGNFTG-SVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
             PSSTP           ++     TG +V P  S  T RTP    S++  P T  +T  P
Sbjct: 4380 TPSSTP-----GTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTP 4434

Query: 260  SN---TSWAP----TTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS-GAPVSP- 310
            S+   T+  P    TTT+            + Q  G+T T     P+ TA + G  +SP 
Sbjct: 4435 SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPP--VPNTTATTHGRSLSPS 4492

Query: 311  ----------QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
                       A        H  +P  G SH+ +  T T   S P         A + P 
Sbjct: 4493 SPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTP---------ALSSPH 4543

Query: 361  PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
            P++  T+ S PS G     +TTP   T  SR + +T + +K  T +TL  +    +P++T
Sbjct: 4544 PSS-RTTESPPSPG-----TTTPGHTTATSRTT-ATATPSKTRT-STLLPSSPTSAPITT 4595

Query: 421  VVST 424
            VV+T
Sbjct: 4596 VVTT 4599



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 100/429 (23%), Positives = 138/429 (32%), Gaps = 71/429 (16%)

Query: 47   PGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTA 106
            P T  TA  SST  T+ ++         +      A P+      PP   +++ A T TA
Sbjct: 3558 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTA 3617

Query: 107  PHSESSLSTGPAPA------------------------AMATTSSKPEGRPRGQAA-PTI 141
              S+++ S+ P  A                         + TT + PE      A   TI
Sbjct: 3618 TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTI 3677

Query: 142  LLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
              +  P  T   T    + TT R      +     G +           + +  G     
Sbjct: 3678 HPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTA-T 3736

Query: 202  PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSN 261
            PSSTP                  T  +  EPST    T   G +++       A T+   
Sbjct: 3737 PSSTP-----------------GTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVL 3779

Query: 262  TSWAPTTT---SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP-------- 310
            TS A T T   S       PG   A     ST T    TP AT+ +  P S         
Sbjct: 3780 TSTATTPTVISSRATPSSSPGTATALPALRSTAT----TPTATSVTAIPSSSLGTAWTRL 3835

Query: 311  QAAPVPSQRPHHGDPQDGPS--HSDSWLTVTPGTSRPLST----SSGVFTAATGPTPAAF 364
                 P+       P   P   H+ + LT T  T+R   +    SS   TA T   P   
Sbjct: 3836 SQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT 3895

Query: 365  DTSVSAPSQGIPQGA-------STTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSP 417
             T  +A     P  A       STT    T  S V+ S+I G         T T  V + 
Sbjct: 3896 TTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3955

Query: 418  LSTVVSTAT 426
                 S++T
Sbjct: 3956 SMATPSSST 3964



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 108/423 (25%), Positives = 162/423 (38%), Gaps = 58/423 (13%)

Query: 33   SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGH 91
            +P  S   +PS TP  T +    ++T  T+     T  P   P      +  P+  A   
Sbjct: 3055 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWI-LTEPSTTATVT 3113

Query: 92   PPTH---TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPG 148
             PT    T S+  AT   PH  ++ +T    ++ AT  S P G      A     T P  
Sbjct: 3114 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSP-GTATALPALRSTATTPTA 3172

Query: 149  A--TSRPTTAPPRTTTR-RPPRPPGSSRKGAGNSSRPVPPAPG---GHSRSKEGQRG--R 200
               T+ P+++   T TR      P ++   A  SS P           + +  G  G   
Sbjct: 3173 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVA 3232

Query: 201  NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRT-PLWGYSSSPQPQTVAATTVP 259
             PSSTP        K+       FT +  P  S  T RT P+W  S++  P T  +T  P
Sbjct: 3233 TPSSTP--GTAHTTKVLTTTTTGFTAT--PSSSPGTARTLPVW-ISTTTTPTTRGSTVTP 3287

Query: 260  SN---TSWAP----TTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS-GAPVSPQ 311
            S+   T+  P    TTT+            + Q  G+T T     P+ TA + G  +SP 
Sbjct: 3288 SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPP--VPNTTATTHGRSLSPS 3345

Query: 312  AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGT------SRPLSTSSGVFTAATG----PTP 361
            +       PH        +   +W + T GT      + P + +S    A TG     TP
Sbjct: 3346 S-------PH--------TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTP 3390

Query: 362  AAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEET-VATLTMTDRVPSPLST 420
            A      S+ +   P    TT   P H    S +T +    +T  +TL  +    +P++T
Sbjct: 3391 ALSSPHPSSRTTESPPSPGTT--TPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITT 3448

Query: 421  VVS 423
            VV+
Sbjct: 3449 VVT 3451



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 82/306 (26%), Positives = 113/306 (36%), Gaps = 33/306 (10%)

Query: 45   TPPGTMVTAPHSSTR---HTSVVM-LTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            TP  TM TA  SST    HTS V+  T    G     A P +TP          HT   +
Sbjct: 3195 TPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTP-------GTAHTTKVL 3247

Query: 101  AATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
              T T   +  S S G A       S+      RG    T+  +  PG T  PT     T
Sbjct: 3248 TTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGS---TVTPSSIPGTTHTPTVLTTTT 3304

Query: 161  TT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
            TT        P SS + +G +    PP P  ++ +    R  +PSS    +         
Sbjct: 3305 TTVATGSMATPSSSTQTSGTTH--TPPVP--NTTATTHGRSLSPSSPHTVRTAWTSAT-- 3358

Query: 219  IYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP 278
               G    +   EPST T  TP     ++       ++  PS+ +   T +   P    P
Sbjct: 3359 --SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRT---TESPPSPGTTTP 3413

Query: 279  GLRRAAQGGGSTFTSQGGTPDATAASG-APVSPQAAPVPSQRPHHGDPQDGPSHSDSWLT 337
            G  RA     ++ T+   TP  T  S   P SP +AP+ +      +PQ   S    +  
Sbjct: 3414 GHTRA-----TSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 3468

Query: 338  VTPGTS 343
              PG S
Sbjct: 3469 PMPGPS 3474



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 90/344 (26%), Positives = 127/344 (36%), Gaps = 37/344 (10%)

Query: 45   TPPGTMVTAPHSS---TRHTSVVMLTPNPDGPPSQAAAPMATP--TPRAEGHPPTHTIST 99
            TP  TM TA  SS   T HTS V+ T       ++A   +ATP  TP         T +T
Sbjct: 4342 TPTATMSTATPSSTPETAHTSTVLTT---TATTTRATGSVATPSSTPGTAHTTKVPTTTT 4398

Query: 100  IAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPR 159
               TVT   S  +  T P   +  TT +         +  T+  +  PG T  PT     
Sbjct: 4399 TGFTVTPSSSPGTARTPPVWISTTTTPT--------TSGSTVTPSSVPGTTHTPTVLTTT 4450

Query: 160  TTT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIF 217
            TTT        P SS + +G +    PP P  ++ +    R  +PSS    +        
Sbjct: 4451 TTTVATGSMATPSSSTQTSGTTH--TPPVP--NTTATTHGRSLSPSSPHTVRTAWTSAT- 4505

Query: 218  QIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDK 277
                G    +   EPST T  TP     ++    T  +T   S+   +  TT   P+   
Sbjct: 4506 ---SGTLGTTHITEPSTGTSHTP-----AATTGTTQHSTPALSSPHPSSRTTESPPS--- 4554

Query: 278  PGLRRAAQGGGSTFTSQGGTPDATAASG-APVSPQAAPVPSQRPHHGDPQDGPSHSDSWL 336
            PG         ++ T+   TP  T  S   P SP +AP+ +      +PQ   S    + 
Sbjct: 4555 PGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYS 4614

Query: 337  TVTPGTS-RPLSTSSGVFTAATGPTPAAFDTSVSAPSQ-GIPQG 378
               PG S     T S +  A              A +Q G+P G
Sbjct: 4615 YPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLG 4658



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 88/325 (27%), Positives = 122/325 (37%), Gaps = 40/325 (12%)

Query: 32   PSPRESL-----QVLPSGTPPGTMVTAPHSS---TRHTSVVM-LTPNPDGPPSQAAAPMA 82
            P P  SL     ++  + TP  TM TA  SS   T HTS V+  T    G     A P +
Sbjct: 2675 PIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2734

Query: 83   TPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTIL 142
            TP        PT T +   AT       SS  T   P    +T++ P  R       T+ 
Sbjct: 2735 TPGTAHTTKVPTTTTTGFTAT-----PSSSPGTALTPPVWISTTTTPTTR-----GSTVT 2784

Query: 143  LTKPPGATSRPTTAPPRTTT--RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGR 200
             +  PG T   T     TTT        P SS + +G +    PP P   + +     GR
Sbjct: 2785 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTH--TPPVPNTMATT----HGR 2838

Query: 201  NPSSTPLGQKRPLGKIFQIYKGNFTGSVE-PEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
               S P      +   +        G+    EPST+T  T L   + + Q  T A ++ P
Sbjct: 2839 ---SLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT-LAATTGTTQHSTPALSS-P 2893

Query: 260  SNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG-APVSPQAAPVPSQ 318
              +S    TT   P+   PG         ++ T+   TP  T  S   P SP +AP+ + 
Sbjct: 2894 HPSS---RTTESPPS---PGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2947

Query: 319  RPHHGDPQDGPSHSDSWLTVTPGTS 343
                 +PQ   S    +    PG S
Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPS 2972



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 116/520 (22%), Positives = 168/520 (32%), Gaps = 123/520 (23%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAA------APMATPTPRAEGHPP----- 93
            TP  T  TA  +    T+    T  P   P  A       +   TPT R     P     
Sbjct: 3233 TPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPG 3292

Query: 94   -THTISTIAATVTA--------PHSESSLS----TGPAPAAMATTSSKPEGRPRGQAAPT 140
             THT + +  T T         P S +  S    T P P   ATT     GR    ++P 
Sbjct: 3293 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATT----HGRSLSPSSPH 3348

Query: 141  ILLTKPPGATSRPT-----TAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKE 195
             + T    ATS        T P   T+  P    G+++      S P       H  S+ 
Sbjct: 3349 TVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSP-------HPSSRT 3401

Query: 196  GQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEP---STLTPRTPLWGYSSSPQPQT 252
             +   +P +T  G  R   +         T +  P     STL P +P     +S    T
Sbjct: 3402 TESPPSPGTTTPGHTRATSRT--------TATATPSKTRTSTLLPSSP-----TSAPITT 3448

Query: 253  VAATTVPSNTSWA-------PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
            V         +W+       P     G   D     RAA GG       G    A A  G
Sbjct: 3449 VVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA-GGAVCEQPLGLECRAQAQPG 3507

Query: 306  APV---------SPQAAPVPSQRPHHGD-------------------PQDGPSHSDSWLT 337
             P+         S     V   R   G                    P    + S +  +
Sbjct: 3508 VPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPS 3567

Query: 338  VTPGTSRPLS--TSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSES 395
             TPGT+  L+  T++   TA TG T     T  +AP   +    +TTP A +        
Sbjct: 3568 STPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-------- 3619

Query: 396  TISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNIS------- 448
                    + AT + + R  + L  + STAT +      P  ++  GT G +        
Sbjct: 3620 --------SKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPM 3671

Query: 449  ------HVAEGDKPQHRATICLSKMDIAWVILAISVPISS 482
                  H +   +  H +T+  +K        ++S P S+
Sbjct: 3672 ATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSST 3711



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 105/438 (23%), Positives = 151/438 (34%), Gaps = 102/438 (23%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            SGT   T +T P + T HT                  P AT        P   +    + 
Sbjct: 4506 SGTLGTTHITEPSTGTSHT------------------PAATTGTTQHSTPALSSPHPSSR 4547

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
            T  +P S  + + G   A   TT++    + R     T+L        S PT+AP  T  
Sbjct: 4548 TTESPPSPGTTTPGHTTATSRTTATATPSKTR---TSTLL-------PSSPTSAPITTVV 4597

Query: 163  RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQR--GRNPSSTPLGQK--------RP 212
                 P  +  +   + S P+P   GG   +    R  G      PLG +         P
Sbjct: 4598 TTGCEPQCAWSEWL-DYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 4656

Query: 213  LGKIFQIYK---------------GNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT 257
            LG++ Q+ +               G F      E      R     Y   P     ++T 
Sbjct: 4657 LGELGQVVECSLDFGLVCRNREQVGKFKMCFNYE-----IRVFCCNYGHCPSTPATSSTA 4711

Query: 258  VPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPS 317
            +PS+T   P TT +                    T    T   TA++G+  +P + P  +
Sbjct: 4712 MPSST---PGTTWI-------------------LTELTTTATTTASTGSTATPSSTPGTA 4749

Query: 318  QRPH-HGDPQDGPSHSDSWLTVT----PGTSRPLSTSSGVFTAATGPTP---AAFDTSVS 369
              P     P   P+ + S  T +      T+ P+ TS+   + AT  TP   +   T+ +
Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 370  APSQGIPQGASTTPQA---PTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVST-A 425
             P Q      +TTP A     HPS   E+T +     T AT   T R  S  ST  ST  
Sbjct: 4810 LPEQ------TTTPVATMSTIHPSSTPETTHTSTVLTTKAT---TTRATSSTSTPSSTPG 4860

Query: 426  TGNFLNRLVPAGTWKPGT 443
            T   L  L  A T    T
Sbjct: 4861 TTWILTELTTAATTTAAT 4878



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 111/462 (24%), Positives = 160/462 (34%), Gaps = 93/462 (20%)

Query: 48   GTMVTAPHSSTRHTSVVMLTPNPDG---------PPSQAAAPMATPTPRAEG-------- 90
            G+M T P SST+ +      P P+          PPS         T    G        
Sbjct: 2808 GSMAT-PSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 2866

Query: 91   HPPTHTISTIAATV-TAPHSESSLSTGPAPAAMATTSSKPEGRP---RGQAAPTILLTKP 146
             P T T  T+AAT  T  HS  +LS+ P P++  T S    G        A      T  
Sbjct: 2867 EPSTVTSHTLAATTGTTQHSTPALSS-PHPSSRTTESPPSPGTTTPGHTTATSRTTATAT 2925

Query: 147  PGAT-------SRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQR- 198
            P  T       S PT+AP  T       P  +  +   + S P+P   GG   +    R 
Sbjct: 2926 PSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWL-DYSYPMPGPSGGDFDTYSNIRA 2984

Query: 199  -GRNPSSTPLGQK-----------RPLGKIFQI------------YKGNFTGSVEPEPST 234
             G      PLG +           R LG++ +               G F      E   
Sbjct: 2985 AGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI-- 3042

Query: 235  LTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQ 294
               R     Y   P     ++T +PS+T   P TT +    +        +  GST T  
Sbjct: 3043 ---RVFCCNYGHCPSTPATSSTAMPSST---PGTTWI--LTELTTTATTTESTGSTATPS 3094

Query: 295  GGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFT 354
              TP  T     P +     VP+          G + + S    T GT    +T++    
Sbjct: 3095 S-TPGTTWILTEPSTTATVTVPT----------GSTATASSTQATAGTPHVSTTATTPTV 3143

Query: 355  AATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTH---PSRVSESTISGAKEETVATLTMT 411
             ++  TP  F +  +A +    +  +TTP A +    PS    +T +   + T  T TM+
Sbjct: 3144 TSSKATP--FSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMS 3201

Query: 412  DRVP---------SPLSTVVSTATGNFLNRLVPAGTWKPGTA 444
               P         S + T  +T TG   +   P+ T  PGTA
Sbjct: 3202 TATPSSTPETVHTSTVLTTTATTTGATGSVATPSST--PGTA 3241



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 99/460 (21%), Positives = 151/460 (32%), Gaps = 78/460 (16%)

Query: 22   TEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPM 81
            T+AL    Q  S     +  P+ T     ++   +S R+TS +  T    GP        
Sbjct: 2317 TQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLG-TATTGGP-------- 2367

Query: 82   ATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGP-------APAAMATTSSKPEGRPR 134
             TP    E   P    ST+      P +  SL T         AP  MAT+ ++P G   
Sbjct: 2368 TTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAS 2427

Query: 135  GQAAPTILLTKPPG-----ATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSR-------- 181
              +   +  +  P      +TS+  T+ PRT T   P    ++ +G              
Sbjct: 2428 TASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWF 2487

Query: 182  ----PVPPAPGGHSRSKEGQRGRN------PSSTPLGQKR----PLGKIFQIYKGNFTGS 227
                P     GG   + E  R         P S     +      + ++ Q+   +    
Sbjct: 2488 DVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETG 2547

Query: 228  VEPEPSTLTPRTPLW-----------GYSSSPQPQTVAATTVPSN---TSW--------A 265
            +  +    T R  +             YS  P     ++T  PS+   T+W        A
Sbjct: 2548 LTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTA 2607

Query: 266  PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP--QAAPVPSQRPHHG 323
             TT S G         R A       T+   TP  T++   P S    A  +P+ R    
Sbjct: 2608 TTTASTGSTATPTSTLRTAP-PPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTAT 2666

Query: 324  DP---QDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAS 380
             P      P  S S  T     S+  + ++ + TA    TP    TS    +     GA+
Sbjct: 2667 TPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGAT 2726

Query: 381  TTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
             +   P+       ST   A    V T T T    +P S+
Sbjct: 2727 GSVATPS-------STPGTAHTTKVPTTTTTGFTATPSSS 2759



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 59/234 (25%), Positives = 88/234 (37%), Gaps = 56/234 (23%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATV 104
            TPP T      ++T  T  +  TP P   P    AP A+ T           + T++  +
Sbjct: 2302 TPPPT-TELETATTTTTQALFSTPQPTSSPGLTRAPPASTT----------AVPTLSEGL 2350

Query: 105  TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRR 164
            T+P   S+L T       ATT       P G   PT+     PG  +  +T P R+    
Sbjct: 2351 TSPRYTSTLGT-------ATTGGPT--TPAGSTEPTV-----PGVAT--STLPTRSAL-- 2392

Query: 165  PPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNF 224
                PG++  G+  + RP  P                P++    + RP G          
Sbjct: 2393 ----PGTT--GSLGTWRPSQPPT------------LAPTTMATSRARPTGTA-------S 2427

Query: 225  TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP 278
            T S EP  ++L P   L    S+ Q +T    T  + +    TTTS G  + +P
Sbjct: 2428 TASKEPLTTSLAP--TLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQP 2479



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 50/160 (31%), Positives = 63/160 (39%), Gaps = 28/160 (17%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVV---MLTPNPD----GPPSQAAAPMATP 84
            P+ R S  V PS  P GT  TA   +T  T+V    M TP+      G       P  T 
Sbjct: 3923 PTTRGST-VTPSSIP-GTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTA 3980

Query: 85   TPRAEGHPPT--HTISTIAATVTA-----PH-SESSLSTGPAPAAMATTSSKPEGRPRGQ 136
            T      PP+  HT+ T   + T+      H +E S  T   PAA  TTS+     P   
Sbjct: 3981 TTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA--TTSTTQHSTPA-- 4036

Query: 137  AAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGA 176
                      P  +SR T +PP   T  P    G+SR  A
Sbjct: 4037 -------LSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTA 4069



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 42/149 (28%), Positives = 58/149 (38%), Gaps = 22/149 (14%)

Query: 42   PSGTPPGTMVTAPHSST---RHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTIS 98
            P+ TP  TM T   SST    HTS V+ T       ++A    ATP+           ++
Sbjct: 5089 PTTTPMSTMSTIHTSSTPETTHTSTVLTTT---ATMTRATNSTATPSSTLGTTRILTELT 5145

Query: 99   TIAATVTAPHSESSLSTGPA-------PAAMAT---------TSSKPEGRPRGQAAPTIL 142
            T A T  A  S ++LS+ P        P+ +AT         T+S   G        T +
Sbjct: 5146 TTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTM 5205

Query: 143  LTKPPGATSRPTTAPPRTTTRRPPRPPGS 171
             T P    S   ++    TTR P   P S
Sbjct: 5206 ATMPTATASTVPSSSTVGTTRTPAVLPSS 5234


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 79/313 (25%), Positives = 115/313 (36%), Gaps = 38/313 (12%)

Query: 66  LTPNPDGPPS--QAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAM- 122
           L P+P+ PP       P   P   +    PT   +T   +VT P + + ++T P    + 
Sbjct: 74  LPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLP 133

Query: 123 --ATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
             ATT S  E      +  T+     P    + TTA P T +   P PP SS   A   +
Sbjct: 134 QNATTISSRENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSS---APPET 188

Query: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
              PP P   +++        PSS+   +               T +  P P   TP  P
Sbjct: 189 TAAPPTPSATTQAP-------PSSSAPPE---------------TTAAPPTPPATTPAPP 226

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
               SSS  P+T AA   PS T+ AP ++S  P  +   +           +S    P+ 
Sbjct: 227 ----SSSAPPETTAAPPTPSATTPAPLSSSAPP--ETTAVPPTPSATTLDPSSASAPPET 280

Query: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
           TAA   P +   AP  S  P         + + S  T+ P TS   +  +   T +    
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 361 PAAFDTSVSAPSQ 373
                   SAP Q
Sbjct: 341 TTTTKQPTSAPGQ 353



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 72/288 (25%), Positives = 106/288 (36%), Gaps = 53/288 (18%)

Query: 51  VTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSE 110
           VT P +ST+ T++  +T  P           AT     E    + +++T+ A V +P  +
Sbjct: 114 VTFPSASTKITTLPNVTFLPQN---------ATTISSRENVNTSSSVATL-APVNSPAPQ 163

Query: 111 SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSR--PTTAPPRTTTRRPPRP 168
            + +  P P+A           P   AAP       P AT++  P+++ P  TT  PP P
Sbjct: 164 DTTAAPPTPSATTPAPPSSSAPPETTAAP-----PTPSATTQAPPSSSAPPETTAAPPTP 218

Query: 169 PGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNF 224
           P ++     +S+ P     PP P               +  PL    P            
Sbjct: 219 PATTPAPPSSSAPPETTAAPPTPSA------------TTPAPLSSSAP----------PE 256

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +V P PS     T L   S+S  P+T AA   PS T+ AP      P+   P    AA
Sbjct: 257 TTAVPPTPSA----TTLDPSSASAPPETTAAPPTPSATTPAP------PSSPAPQETTAA 306

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHS 332
                  +     PD +  S AP       V +Q      P   P  +
Sbjct: 307 PITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQN 354



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 78/286 (27%), Positives = 107/286 (37%), Gaps = 62/286 (21%)

Query: 32  PSPRESLQVLPSGT---PPGTMVTAPHSSTRHTSVVMLTP-NPDGPPSQAAAPMATPTPR 87
           PS    +  LP+ T      T +++  +    +SV  L P N   P    AAP   PTP 
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP---PTP- 172

Query: 88  AEGHPPTHTISTIAATVTAPHSESS--LSTGPAPAAMATTSSKPEGR--PRGQAAPTILL 143
                        +AT  AP S S+   +T   P   ATT + P     P   AAP    
Sbjct: 173 -------------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPP--- 216

Query: 144 TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRG 199
           T P    + P+++ P  TT  PP P  ++     +S+ P    VPP P   +        
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATT-------- 268

Query: 200 RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
            +PSS     +              T +  P PS  TP  P    S +PQ  T A  T P
Sbjct: 269 LDPSSASAPPE--------------TTAAPPTPSATTPAPP---SSPAPQETTAAPITTP 311

Query: 260 SNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
           ++   +PTT  L P   +       Q   S  T    T   T+A G
Sbjct: 312 NS---SPTT--LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 58/201 (28%), Positives = 82/201 (40%), Gaps = 52/201 (25%)

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +  P PS  TP  P    SSS  P+T AA   PS T+ AP ++S              
Sbjct: 165 TTAAPPTPSATTPAPP----SSSAPPETTAAPPTPSATTQAPPSSS-------------- 206

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR 344
                        P+ TAA   P +   AP  S  P        P  + +  T +  T  
Sbjct: 207 -----------APPETTAAPPTPPATTPAPPSSSAP--------PETTAAPPTPSATTPA 247

Query: 345 PLSTSSGVFTAATGPTPAAF---DTSVSAPSQ---GIPQGASTTPQAPTHPSRVSESTIS 398
           PLS+S+   T A  PTP+A     +S SAP +     P  ++TTP  P+ P+        
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPA-------- 299

Query: 399 GAKEETVATLTMTDRVPSPLS 419
             +E T A +T  +  P+ L+
Sbjct: 300 -PQETTAAPITTPNSSPTTLA 319



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 46/166 (27%), Positives = 63/166 (37%), Gaps = 27/166 (16%)

Query: 32  PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATPTPR 87
           P+P  + Q  PS + P     AP +    T      P+   PP   AAP      TP P 
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPA---PPSSSAPPETTAAPPTPSATTPAPL 249

Query: 88  AEGHPPTHTI--STIAATVTAPHSESSL-STGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
           +   PP  T    T +AT   P S S+   T  AP   + T+  P   P  Q      +T
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 145 KPPGA-------TSRPTTAPPR----------TTTRRPPRPPGSSR 173
            P  +       TS  + AP            TTT++P   PG ++
Sbjct: 310 TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 67/248 (27%), Positives = 93/248 (37%), Gaps = 63/248 (25%)

Query: 29  IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATP 84
           +  P+P+++    P  TP  T    P SS               PP   AAP      T 
Sbjct: 157 VNSPAPQDTTAAPP--TPSATTPAPPSSSA--------------PPETTAAPPTPSATTQ 200

Query: 85  TPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
            P +   PP     T AA  T P      +T PAP     +SS P   P   AAP     
Sbjct: 201 APPSSSAPP----ETTAAPPTPP------ATTPAP----PSSSAP---PETTAAPPTPSA 243

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGR 200
             P   S  ++APP TT   PP P  ++   +  S+ P     PP P   + +       
Sbjct: 244 TTPAPLS--SSAPPETTA-VPPTPSATTLDPSSASAPPETTAAPPTPSATTPA------- 293

Query: 201 NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
            P S+P  Q+     I          +    P+TL P T     S++P  QT  + T  +
Sbjct: 294 -PPSSPAPQETTAAPI---------TTPNSSPTTLAPDTS--ETSAAPTHQTTTSVTTQT 341

Query: 261 NTSWAPTT 268
            T+  PT+
Sbjct: 342 TTTKQPTS 349



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 12/191 (6%)

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
           PS  T  T L   +  PQ  T  ++    NTS +  T  L P         A Q   +  
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVAT--LAPVNSP-----APQDTTAAP 169

Query: 292 TSQGGTPDATAASGAPVSPQAA-PVPSQRPHHGDPQDGPSHSDSWLTVTPGTS-RPLSTS 349
            +   T  A  +S AP    AA P PS           P  + +     P T+  P S+S
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 350 SGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLT 409
           +   T A  PTP+A  T+ +  S   P   +  P  P+  + +  S+ S   E T A  T
Sbjct: 230 APPETTAAPPTPSA--TTPAPLSSSAPPETTAVPPTPS-ATTLDPSSASAPPETTAAPPT 286

Query: 410 MTDRVPSPLST 420
            +   P+P S+
Sbjct: 287 PSATTPAPPSS 297



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 37/157 (23%), Positives = 56/157 (35%), Gaps = 46/157 (29%)

Query: 310 PQAAPVPSQRPHHGDPQDGPSHSDSWLTVT----------PGTSRP-------------- 345
           P+  P P+  P   +P   P H D   +V           P  + P              
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTF 131

Query: 346 -------------LSTSSGVFTAATGPTPAAFDTSVSAPSQG----IPQGASTTPQ---A 385
                        ++TSS V T A   +PA  DT+ + P+       P  +S  P+   A
Sbjct: 132 LPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA 191

Query: 386 PTHPSRVSES--TISGAKEETVATLTMTDRVPSPLST 420
           P  PS  +++  + S   E T A  T     P+P S+
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS 228


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 79/313 (25%), Positives = 115/313 (36%), Gaps = 38/313 (12%)

Query: 66  LTPNPDGPPS--QAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAM- 122
           L P+P+ PP       P   P   +    PT   +T   +VT P + + ++T P    + 
Sbjct: 74  LPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLP 133

Query: 123 --ATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
             ATT S  E      +  T+     P    + TTA P T +   P PP SS   A   +
Sbjct: 134 QNATTISSRENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSS---APPET 188

Query: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
              PP P   +++        PSS+   +               T +  P P   TP  P
Sbjct: 189 TAAPPTPSATTQAP-------PSSSAPPE---------------TTAAPPTPPATTPAPP 226

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
               SSS  P+T AA   PS T+ AP ++S  P  +   +           +S    P+ 
Sbjct: 227 ----SSSAPPETTAAPPTPSATTPAPLSSSAPP--ETTAVPPTPSATTLDPSSASAPPET 280

Query: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
           TAA   P +   AP  S  P         + + S  T+ P TS   +  +   T +    
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 361 PAAFDTSVSAPSQ 373
                   SAP Q
Sbjct: 341 TTTTKQPTSAPGQ 353



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 72/288 (25%), Positives = 106/288 (36%), Gaps = 53/288 (18%)

Query: 51  VTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSE 110
           VT P +ST+ T++  +T  P           AT     E    + +++T+ A V +P  +
Sbjct: 114 VTFPSASTKITTLPNVTFLPQN---------ATTISSRENVNTSSSVATL-APVNSPAPQ 163

Query: 111 SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSR--PTTAPPRTTTRRPPRP 168
            + +  P P+A           P   AAP       P AT++  P+++ P  TT  PP P
Sbjct: 164 DTTAAPPTPSATTPAPPSSSAPPETTAAP-----PTPSATTQAPPSSSAPPETTAAPPTP 218

Query: 169 PGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNF 224
           P ++     +S+ P     PP P               +  PL    P            
Sbjct: 219 PATTPAPPSSSAPPETTAAPPTPSA------------TTPAPLSSSAP----------PE 256

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +V P PS     T L   S+S  P+T AA   PS T+ AP      P+   P    AA
Sbjct: 257 TTAVPPTPSA----TTLDPSSASAPPETTAAPPTPSATTPAP------PSSPAPQETTAA 306

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHS 332
                  +     PD +  S AP       V +Q      P   P  +
Sbjct: 307 PITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQN 354



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 78/286 (27%), Positives = 107/286 (37%), Gaps = 62/286 (21%)

Query: 32  PSPRESLQVLPSGT---PPGTMVTAPHSSTRHTSVVMLTP-NPDGPPSQAAAPMATPTPR 87
           PS    +  LP+ T      T +++  +    +SV  L P N   P    AAP   PTP 
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP---PTP- 172

Query: 88  AEGHPPTHTISTIAATVTAPHSESS--LSTGPAPAAMATTSSKPEGR--PRGQAAPTILL 143
                        +AT  AP S S+   +T   P   ATT + P     P   AAP    
Sbjct: 173 -------------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPP--- 216

Query: 144 TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRG 199
           T P    + P+++ P  TT  PP P  ++     +S+ P    VPP P   +        
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATT-------- 268

Query: 200 RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
            +PSS     +              T +  P PS  TP  P    S +PQ  T A  T P
Sbjct: 269 LDPSSASAPPE--------------TTAAPPTPSATTPAPP---SSPAPQETTAAPITTP 311

Query: 260 SNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
           ++   +PTT  L P   +       Q   S  T    T   T+A G
Sbjct: 312 NS---SPTT--LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 58/201 (28%), Positives = 82/201 (40%), Gaps = 52/201 (25%)

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +  P PS  TP  P    SSS  P+T AA   PS T+ AP ++S              
Sbjct: 165 TTAAPPTPSATTPAPP----SSSAPPETTAAPPTPSATTQAPPSSS-------------- 206

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR 344
                        P+ TAA   P +   AP  S  P        P  + +  T +  T  
Sbjct: 207 -----------APPETTAAPPTPPATTPAPPSSSAP--------PETTAAPPTPSATTPA 247

Query: 345 PLSTSSGVFTAATGPTPAAF---DTSVSAPSQ---GIPQGASTTPQAPTHPSRVSESTIS 398
           PLS+S+   T A  PTP+A     +S SAP +     P  ++TTP  P+ P+        
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPA-------- 299

Query: 399 GAKEETVATLTMTDRVPSPLS 419
             +E T A +T  +  P+ L+
Sbjct: 300 -PQETTAAPITTPNSSPTTLA 319



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 46/166 (27%), Positives = 63/166 (37%), Gaps = 27/166 (16%)

Query: 32  PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATPTPR 87
           P+P  + Q  PS + P     AP +    T      P+   PP   AAP      TP P 
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPA---PPSSSAPPETTAAPPTPSATTPAPL 249

Query: 88  AEGHPPTHTI--STIAATVTAPHSESSL-STGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
           +   PP  T    T +AT   P S S+   T  AP   + T+  P   P  Q      +T
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 145 KPPGA-------TSRPTTAPPR----------TTTRRPPRPPGSSR 173
            P  +       TS  + AP            TTT++P   PG ++
Sbjct: 310 TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 67/248 (27%), Positives = 93/248 (37%), Gaps = 63/248 (25%)

Query: 29  IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATP 84
           +  P+P+++    P  TP  T    P SS               PP   AAP      T 
Sbjct: 157 VNSPAPQDTTAAPP--TPSATTPAPPSSSA--------------PPETTAAPPTPSATTQ 200

Query: 85  TPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
            P +   PP     T AA  T P      +T PAP     +SS P   P   AAP     
Sbjct: 201 APPSSSAPP----ETTAAPPTPP------ATTPAP----PSSSAP---PETTAAPPTPSA 243

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGR 200
             P   S  ++APP TT   PP P  ++   +  S+ P     PP P   + +       
Sbjct: 244 TTPAPLS--SSAPPETTA-VPPTPSATTLDPSSASAPPETTAAPPTPSATTPA------- 293

Query: 201 NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
            P S+P  Q+     I          +    P+TL P T     S++P  QT  + T  +
Sbjct: 294 -PPSSPAPQETTAAPI---------TTPNSSPTTLAPDTS--ETSAAPTHQTTTSVTTQT 341

Query: 261 NTSWAPTT 268
            T+  PT+
Sbjct: 342 TTTKQPTS 349



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 12/191 (6%)

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
           PS  T  T L   +  PQ  T  ++    NTS +  T  L P         A Q   +  
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVAT--LAPVNSP-----APQDTTAAP 169

Query: 292 TSQGGTPDATAASGAPVSPQAA-PVPSQRPHHGDPQDGPSHSDSWLTVTPGTS-RPLSTS 349
            +   T  A  +S AP    AA P PS           P  + +     P T+  P S+S
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 350 SGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLT 409
           +   T A  PTP+A  T+ +  S   P   +  P  P+  + +  S+ S   E T A  T
Sbjct: 230 APPETTAAPPTPSA--TTPAPLSSSAPPETTAVPPTPS-ATTLDPSSASAPPETTAAPPT 286

Query: 410 MTDRVPSPLST 420
            +   P+P S+
Sbjct: 287 PSATTPAPPSS 297



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 37/157 (23%), Positives = 56/157 (35%), Gaps = 46/157 (29%)

Query: 310 PQAAPVPSQRPHHGDPQDGPSHSDSWLTVT----------PGTSRP-------------- 345
           P+  P P+  P   +P   P H D   +V           P  + P              
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTF 131

Query: 346 -------------LSTSSGVFTAATGPTPAAFDTSVSAPSQG----IPQGASTTPQ---A 385
                        ++TSS V T A   +PA  DT+ + P+       P  +S  P+   A
Sbjct: 132 LPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA 191

Query: 386 PTHPSRVSES--TISGAKEETVATLTMTDRVPSPLST 420
           P  PS  +++  + S   E T A  T     P+P S+
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS 228


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 79/313 (25%), Positives = 115/313 (36%), Gaps = 38/313 (12%)

Query: 66  LTPNPDGPPS--QAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAM- 122
           L P+P+ PP       P   P   +    PT   +T   +VT P + + ++T P    + 
Sbjct: 74  LPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLP 133

Query: 123 --ATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSS 180
             ATT S  E      +  T+     P    + TTA P T +   P PP SS   A   +
Sbjct: 134 QNATTISSRENVNTSSSVATLAPVNSPAP--QDTTAAPPTPSATTPAPPSSS---APPET 188

Query: 181 RPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
              PP P   +++        PSS+   +               T +  P P   TP  P
Sbjct: 189 TAAPPTPSATTQAP-------PSSSAPPE---------------TTAAPPTPPATTPAPP 226

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
               SSS  P+T AA   PS T+ AP ++S  P  +   +           +S    P+ 
Sbjct: 227 ----SSSAPPETTAAPPTPSATTPAPLSSSAPP--ETTAVPPTPSATTLDPSSASAPPET 280

Query: 301 TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
           TAA   P +   AP  S  P         + + S  T+ P TS   +  +   T +    
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 361 PAAFDTSVSAPSQ 373
                   SAP Q
Sbjct: 341 TTTTKQPTSAPGQ 353



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 72/288 (25%), Positives = 106/288 (36%), Gaps = 53/288 (18%)

Query: 51  VTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSE 110
           VT P +ST+ T++  +T  P           AT     E    + +++T+ A V +P  +
Sbjct: 114 VTFPSASTKITTLPNVTFLPQN---------ATTISSRENVNTSSSVATL-APVNSPAPQ 163

Query: 111 SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSR--PTTAPPRTTTRRPPRP 168
            + +  P P+A           P   AAP       P AT++  P+++ P  TT  PP P
Sbjct: 164 DTTAAPPTPSATTPAPPSSSAPPETTAAP-----PTPSATTQAPPSSSAPPETTAAPPTP 218

Query: 169 PGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNF 224
           P ++     +S+ P     PP P               +  PL    P            
Sbjct: 219 PATTPAPPSSSAPPETTAAPPTPSA------------TTPAPLSSSAP----------PE 256

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +V P PS     T L   S+S  P+T AA   PS T+ AP      P+   P    AA
Sbjct: 257 TTAVPPTPSA----TTLDPSSASAPPETTAAPPTPSATTPAP------PSSPAPQETTAA 306

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHS 332
                  +     PD +  S AP       V +Q      P   P  +
Sbjct: 307 PITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQN 354



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 78/286 (27%), Positives = 107/286 (37%), Gaps = 62/286 (21%)

Query: 32  PSPRESLQVLPSGT---PPGTMVTAPHSSTRHTSVVMLTP-NPDGPPSQAAAPMATPTPR 87
           PS    +  LP+ T      T +++  +    +SV  L P N   P    AAP   PTP 
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAP---PTP- 172

Query: 88  AEGHPPTHTISTIAATVTAPHSESS--LSTGPAPAAMATTSSKPEGR--PRGQAAPTILL 143
                        +AT  AP S S+   +T   P   ATT + P     P   AAP    
Sbjct: 173 -------------SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPP--- 216

Query: 144 TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRG 199
           T P    + P+++ P  TT  PP P  ++     +S+ P    VPP P   +        
Sbjct: 217 TPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATT-------- 268

Query: 200 RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
            +PSS     +              T +  P PS  TP  P    S +PQ  T A  T P
Sbjct: 269 LDPSSASAPPE--------------TTAAPPTPSATTPAPP---SSPAPQETTAAPITTP 311

Query: 260 SNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASG 305
           ++   +PTT  L P   +       Q   S  T    T   T+A G
Sbjct: 312 NS---SPTT--LAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPG 352



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 58/201 (28%), Positives = 82/201 (40%), Gaps = 52/201 (25%)

Query: 225 TGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAA 284
           T +  P PS  TP  P    SSS  P+T AA   PS T+ AP ++S              
Sbjct: 165 TTAAPPTPSATTPAPP----SSSAPPETTAAPPTPSATTQAPPSSS-------------- 206

Query: 285 QGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSR 344
                        P+ TAA   P +   AP  S  P        P  + +  T +  T  
Sbjct: 207 -----------APPETTAAPPTPPATTPAPPSSSAP--------PETTAAPPTPSATTPA 247

Query: 345 PLSTSSGVFTAATGPTPAAF---DTSVSAPSQ---GIPQGASTTPQAPTHPSRVSESTIS 398
           PLS+S+   T A  PTP+A     +S SAP +     P  ++TTP  P+ P+        
Sbjct: 248 PLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPA-------- 299

Query: 399 GAKEETVATLTMTDRVPSPLS 419
             +E T A +T  +  P+ L+
Sbjct: 300 -PQETTAAPITTPNSSPTTLA 319



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 46/166 (27%), Positives = 63/166 (37%), Gaps = 27/166 (16%)

Query: 32  PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATPTPR 87
           P+P  + Q  PS + P     AP +    T      P+   PP   AAP      TP P 
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPA---PPSSSAPPETTAAPPTPSATTPAPL 249

Query: 88  AEGHPPTHTI--STIAATVTAPHSESSL-STGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
           +   PP  T    T +AT   P S S+   T  AP   + T+  P   P  Q      +T
Sbjct: 250 SSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 145 KPPGA-------TSRPTTAPPR----------TTTRRPPRPPGSSR 173
            P  +       TS  + AP            TTT++P   PG ++
Sbjct: 310 TPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNK 355



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 67/248 (27%), Positives = 93/248 (37%), Gaps = 63/248 (25%)

Query: 29  IQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAP----MATP 84
           +  P+P+++    P  TP  T    P SS               PP   AAP      T 
Sbjct: 157 VNSPAPQDTTAAPP--TPSATTPAPPSSSA--------------PPETTAAPPTPSATTQ 200

Query: 85  TPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLT 144
            P +   PP     T AA  T P      +T PAP     +SS P   P   AAP     
Sbjct: 201 APPSSSAPP----ETTAAPPTPP------ATTPAP----PSSSAP---PETTAAPPTPSA 243

Query: 145 KPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGR 200
             P   S  ++APP TT   PP P  ++   +  S+ P     PP P   + +       
Sbjct: 244 TTPAPLS--SSAPPETTA-VPPTPSATTLDPSSASAPPETTAAPPTPSATTPA------- 293

Query: 201 NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
            P S+P  Q+     I          +    P+TL P T     S++P  QT  + T  +
Sbjct: 294 -PPSSPAPQETTAAPI---------TTPNSSPTTLAPDTS--ETSAAPTHQTTTSVTTQT 341

Query: 261 NTSWAPTT 268
            T+  PT+
Sbjct: 342 TTTKQPTS 349



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 52/191 (27%), Positives = 75/191 (39%), Gaps = 12/191 (6%)

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
           PS  T  T L   +  PQ  T  ++    NTS +  T  L P         A Q   +  
Sbjct: 117 PSASTKITTLPNVTFLPQNATTISSRENVNTSSSVAT--LAPVNSP-----APQDTTAAP 169

Query: 292 TSQGGTPDATAASGAPVSPQAA-PVPSQRPHHGDPQDGPSHSDSWLTVTPGTS-RPLSTS 349
            +   T  A  +S AP    AA P PS           P  + +     P T+  P S+S
Sbjct: 170 PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229

Query: 350 SGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLT 409
           +   T A  PTP+A  T+ +  S   P   +  P  P+  + +  S+ S   E T A  T
Sbjct: 230 APPETTAAPPTPSA--TTPAPLSSSAPPETTAVPPTPS-ATTLDPSSASAPPETTAAPPT 286

Query: 410 MTDRVPSPLST 420
            +   P+P S+
Sbjct: 287 PSATTPAPPSS 297



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 37/157 (23%), Positives = 56/157 (35%), Gaps = 46/157 (29%)

Query: 310 PQAAPVPSQRPHHGDPQDGPSHSDSWLTVT----------PGTSRP-------------- 345
           P+  P P+  P   +P   P H D   +V           P  + P              
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTF 131

Query: 346 -------------LSTSSGVFTAATGPTPAAFDTSVSAPSQG----IPQGASTTPQ---A 385
                        ++TSS V T A   +PA  DT+ + P+       P  +S  P+   A
Sbjct: 132 LPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAA 191

Query: 386 PTHPSRVSES--TISGAKEETVATLTMTDRVPSPLST 420
           P  PS  +++  + S   E T A  T     P+P S+
Sbjct: 192 PPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSS 228


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 104/438 (23%), Positives = 141/438 (32%), Gaps = 62/438 (14%)

Query: 30  QEPSP---RESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           +EP+P   +E     P    P T      ++T+        P P  P   A      P P
Sbjct: 260 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 319

Query: 87  RAEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTK 145
                P   T    A T   P   +     P AP   A T+ K E  P     P    TK
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTK 378

Query: 146 PPGATSR----PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
            P  T+     PTT     TT + P P           S P  P     + +KE      
Sbjct: 379 EPSPTTPKEPAPTTTKSAPTTTKEPAP-------TTTKSAPTTPKEPSPTTTKEPAPTTP 431

Query: 202 PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQT--VAATTVP 259
               P   K+P              +   EP+  TP+ P    +  P P T    A T P
Sbjct: 432 KEPAPTTPKKP------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479

Query: 260 SNTSWAPT---------------TTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS 304
             T  APT               TT   PA   P           T T+       T  +
Sbjct: 480 KET--APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537

Query: 305 GAPVSP-QAAPVPSQRPHHGDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPA 362
            AP +P + AP   + P    P++  P+        TP  + P +      T    P P 
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597

Query: 363 AF---------DTSVSAPSQGIPQG-ASTTPQ--APTHPSRVSESTISGAKEETV-ATLT 409
                       T+   P+   P+G A TTP+  APT P   + +T  G    T+     
Sbjct: 598 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 657

Query: 410 MTDRVPSPLSTVVSTATG 427
            T + P+P     +T  G
Sbjct: 658 TTPKKPAPKELAPTTTKG 675



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 95/426 (22%), Positives = 139/426 (32%), Gaps = 42/426 (9%)

Query: 30  QEPSPR--ESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
           +EP+P   +S    P    P T  +AP +           P P  P   A      P P 
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289

Query: 88  AEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTKP 146
                PT        T   P   +     P  P     T+ K       + APT      
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST- 205
           P A  +P    P+      P+ P  +     + + P  PAP     +    +   P++T 
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409

Query: 206 --PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS 263
             P   K P            + +   EP+  TP+ P       P P T       +   
Sbjct: 410 SAPTTPKEP------------SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457

Query: 264 WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHH 322
            APTTT   PA   P  +  A       T+   T   T     P +P+  AP   ++P  
Sbjct: 458 PAPTTTK-KPAPTTP--KEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 508

Query: 323 GDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP-QGAS 380
             P++  P+  +     TP    P +  +        P P    T+   P+   P + A 
Sbjct: 509 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAP 564

Query: 381 TTPQ--APTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
           TTP+  APT P   + +T+      T       +  P+      ST          PA T
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK------PAPT 618

Query: 439 WKPGTA 444
              GTA
Sbjct: 619 TPKGTA 624



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 82/357 (22%), Positives = 121/357 (33%), Gaps = 39/357 (10%)

Query: 45  TPPGTMVTAPH---SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
           T P T  T  +   +S + T+   + P P  PP+   +   + T   E        +T+ 
Sbjct: 100 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE--------TTVE 151

Query: 102 ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              T   ++ + + G      A  +   E       APT  +   P   +  TT  P  T
Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 211

Query: 162 TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYK 221
           T + P P       +     P P        + +        S P   K P         
Sbjct: 212 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------- 262

Query: 222 GNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTV-AATTVPSNTSWAPTTTSLGPAKDKPGL 280
                +   EP+  TP+ P    +  P P T  +A T P     APTT    P K  P  
Sbjct: 263 ---APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTT----PKKPAPTT 313

Query: 281 RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDP-QDGPSHSDSWLTVT 339
            +      +  T +  TP  T    AP + + AP   + P    P +  P+        T
Sbjct: 314 PKEP----APTTPKEPTP-TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368

Query: 340 PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSEST 396
           P    P +T     T    P P    T+ SAP+       +TT  APT P   S +T
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 96/401 (23%), Positives = 128/401 (31%), Gaps = 59/401 (14%)

Query: 30  QEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE 89
           +EPSP  + +  P+ TP     T P             P P  P   A      P P   
Sbjct: 416 KEPSPTTTKEPAPT-TPKEPAPTTPKK-----------PAPTTPKEPAPTTPKEPAPTTT 463

Query: 90  GHPPTHTISTIAATV---TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
             P   T    A T    TAP +   L+         TT  KP      + APT      
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ-RGRNPSS- 204
           P     P    P+      P+ P  +       + P  PAP     +     +G  P++ 
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 583

Query: 205 ---TPLGQKRPLGKIFQ---IYKGNFTGSVEPEPST------LTPRTPLWGYSSSPQPQT 252
               P   K+P  K        +   T   +P P+T       TP+ P       P P T
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 643

Query: 253 VAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP-Q 311
              T   +    APTT    P K  P         G T T+       T    AP +P +
Sbjct: 644 PKGTAPTTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 699

Query: 312 AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAP 371
            AP   ++P                  TP T  P  T+S V T  T   P     S   P
Sbjct: 700 PAPTTPKKP---------------APTTPETPPP--TTSEVSTPTTTKEPTTIHKS---P 739

Query: 372 SQGIPQ-GASTTPQA----PTHPSRVSESTISGAKEETVAT 407
            +  P+  A  TP+A    P  P   +  T +  K E   T
Sbjct: 740 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 133/426 (31%), Gaps = 76/426 (17%)

Query: 33  SPRESLQVLPSGTPPGTMVT--------------APHSSTRHTSVVMLTPNPDGPPSQAA 78
           +P+E+    P GT P T+                AP ++   TS     P P  P   A 
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 79  APMATPTPRAEGHP-PTHTISTIAATVTAPHSESSLSTGPAPAA-------MATTSSKPE 130
                P P     P PT    T   T+  P   +     P   A        +TTS KP 
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP- 684

Query: 131 GRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGH 190
                  APT      P  T+  T   P  TT + P P           + P  P P   
Sbjct: 685 -------APT-----TPKETAPTTPKEPAPTTPKKPAP-----------TTPETPPP--- 718

Query: 191 SRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQP 250
                     +  STP   K P        +     S EP P  L          +SP+ 
Sbjct: 719 --------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL---------ENSPKE 761

Query: 251 QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP 310
             V  T  P+ T    TTT    AKDK    R  +    T T+       TA +    + 
Sbjct: 762 PGVPTTKTPAATKPEMTTT----AKDKT-TERDLRTTPETTTAAPKMTKETATTTEKTTE 816

Query: 311 QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA 370
                 + +      QD      + L  T    +  +T   + T      P       + 
Sbjct: 817 SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP----EETAK 872

Query: 371 PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL 430
           P        +TTP+ P  P++  +   S  K +T+  +      P+P     +    N  
Sbjct: 873 PKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931

Query: 431 NRLVPA 436
           +R+  A
Sbjct: 932 SRIAEA 937



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 36/198 (18%), Positives = 65/198 (32%), Gaps = 13/198 (6%)

Query: 227 SVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQG 286
           S  P+ +T  P  P    S  P   T   T++  N       T++   +     ++ +  
Sbjct: 113 STSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKE-----TTVETKETTTTNKQTSTD 165

Query: 287 GGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPL 346
           G    TS   T      S   ++P +  +    P       GP+        TP    P 
Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA------LTTPKEPTPT 219

Query: 347 STSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVA 406
           +      T    PTP    ++ + P +  P    + P  P  P+  +    +    +  A
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 279

Query: 407 TLTMTDRVPSPLSTVVST 424
             T  +  P+   +  +T
Sbjct: 280 PTTTKEPAPTTTKSAPTT 297


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 104/438 (23%), Positives = 141/438 (32%), Gaps = 62/438 (14%)

Query: 30  QEPSP---RESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           +EP+P   +E     P    P T      ++T+        P P  P   A      P P
Sbjct: 301 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 360

Query: 87  RAEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTK 145
                P   T    A T   P   +     P AP   A T+ K E  P     P    TK
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTK 419

Query: 146 PPGATSR----PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
            P  T+     PTT     TT + P P           S P  P     + +KE      
Sbjct: 420 EPSPTTPKEPAPTTTKSAPTTTKEPAP-------TTTKSAPTTPKEPSPTTTKEPAPTTP 472

Query: 202 PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQT--VAATTVP 259
               P   K+P              +   EP+  TP+ P    +  P P T    A T P
Sbjct: 473 KEPAPTTPKKP------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520

Query: 260 SNTSWAPT---------------TTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS 304
             T  APT               TT   PA   P           T T+       T  +
Sbjct: 521 KET--APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578

Query: 305 GAPVSP-QAAPVPSQRPHHGDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPA 362
            AP +P + AP   + P    P++  P+        TP  + P +      T    P P 
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638

Query: 363 AF---------DTSVSAPSQGIPQG-ASTTPQ--APTHPSRVSESTISGAKEETV-ATLT 409
                       T+   P+   P+G A TTP+  APT P   + +T  G    T+     
Sbjct: 639 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 698

Query: 410 MTDRVPSPLSTVVSTATG 427
            T + P+P     +T  G
Sbjct: 699 TTPKKPAPKELAPTTTKG 716



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 95/426 (22%), Positives = 139/426 (32%), Gaps = 42/426 (9%)

Query: 30  QEPSPR--ESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
           +EP+P   +S    P    P T  +AP +           P P  P   A      P P 
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330

Query: 88  AEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTKP 146
                PT        T   P   +     P  P     T+ K       + APT      
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST- 205
           P A  +P    P+      P+ P  +     + + P  PAP     +    +   P++T 
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450

Query: 206 --PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS 263
             P   K P            + +   EP+  TP+ P       P P T       +   
Sbjct: 451 SAPTTPKEP------------SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498

Query: 264 WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHH 322
            APTTT   PA   P  +  A       T+   T   T     P +P+  AP   ++P  
Sbjct: 499 PAPTTTK-KPAPTTP--KEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 549

Query: 323 GDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP-QGAS 380
             P++  P+  +     TP    P +  +        P P    T+   P+   P + A 
Sbjct: 550 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAP 605

Query: 381 TTPQ--APTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
           TTP+  APT P   + +T+      T       +  P+      ST          PA T
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK------PAPT 659

Query: 439 WKPGTA 444
              GTA
Sbjct: 660 TPKGTA 665



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 82/357 (22%), Positives = 121/357 (33%), Gaps = 39/357 (10%)

Query: 45  TPPGTMVTAPH---SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
           T P T  T  +   +S + T+   + P P  PP+   +   + T   E        +T+ 
Sbjct: 141 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE--------TTVE 192

Query: 102 ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              T   ++ + + G      A  +   E       APT  +   P   +  TT  P  T
Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 252

Query: 162 TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYK 221
           T + P P       +     P P        + +        S P   K P         
Sbjct: 253 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------- 303

Query: 222 GNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTV-AATTVPSNTSWAPTTTSLGPAKDKPGL 280
                +   EP+  TP+ P    +  P P T  +A T P     APTT    P K  P  
Sbjct: 304 ---APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTT----PKKPAPTT 354

Query: 281 RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDP-QDGPSHSDSWLTVT 339
            +      +  T +  TP  T    AP + + AP   + P    P +  P+        T
Sbjct: 355 PKEP----APTTPKEPTP-TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409

Query: 340 PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSEST 396
           P    P +T     T    P P    T+ SAP+       +TT  APT P   S +T
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 96/401 (23%), Positives = 128/401 (31%), Gaps = 59/401 (14%)

Query: 30  QEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE 89
           +EPSP  + +  P+ TP     T P             P P  P   A      P P   
Sbjct: 457 KEPSPTTTKEPAPT-TPKEPAPTTPKK-----------PAPTTPKEPAPTTPKEPAPTTT 504

Query: 90  GHPPTHTISTIAATV---TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
             P   T    A T    TAP +   L+         TT  KP      + APT      
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ-RGRNPSS- 204
           P     P    P+      P+ P  +       + P  PAP     +     +G  P++ 
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 624

Query: 205 ---TPLGQKRPLGKIFQ---IYKGNFTGSVEPEPST------LTPRTPLWGYSSSPQPQT 252
               P   K+P  K        +   T   +P P+T       TP+ P       P P T
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 684

Query: 253 VAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP-Q 311
              T   +    APTT    P K  P         G T T+       T    AP +P +
Sbjct: 685 PKGTAPTTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 740

Query: 312 AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAP 371
            AP   ++P                  TP T  P  T+S V T  T   P     S   P
Sbjct: 741 PAPTTPKKP---------------APTTPETPPP--TTSEVSTPTTTKEPTTIHKS---P 780

Query: 372 SQGIPQ-GASTTPQA----PTHPSRVSESTISGAKEETVAT 407
            +  P+  A  TP+A    P  P   +  T +  K E   T
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 133/426 (31%), Gaps = 76/426 (17%)

Query: 33  SPRESLQVLPSGTPPGTMVT--------------APHSSTRHTSVVMLTPNPDGPPSQAA 78
           +P+E+    P GT P T+                AP ++   TS     P P  P   A 
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 79  APMATPTPRAEGHP-PTHTISTIAATVTAPHSESSLSTGPAPAA-------MATTSSKPE 130
                P P     P PT    T   T+  P   +     P   A        +TTS KP 
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP- 725

Query: 131 GRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGH 190
                  APT      P  T+  T   P  TT + P P           + P  P P   
Sbjct: 726 -------APT-----TPKETAPTTPKEPAPTTPKKPAP-----------TTPETPPP--- 759

Query: 191 SRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQP 250
                     +  STP   K P        +     S EP P  L          +SP+ 
Sbjct: 760 --------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL---------ENSPKE 802

Query: 251 QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP 310
             V  T  P+ T    TTT    AKDK    R  +    T T+       TA +    + 
Sbjct: 803 PGVPTTKTPAATKPEMTTT----AKDKT-TERDLRTTPETTTAAPKMTKETATTTEKTTE 857

Query: 311 QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA 370
                 + +      QD      + L  T    +  +T   + T      P       + 
Sbjct: 858 SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP----EETAK 913

Query: 371 PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL 430
           P        +TTP+ P  P++  +   S  K +T+  +      P+P     +    N  
Sbjct: 914 PKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972

Query: 431 NRLVPA 436
           +R+  A
Sbjct: 973 SRIAEA 978



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 36/198 (18%), Positives = 65/198 (32%), Gaps = 13/198 (6%)

Query: 227 SVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQG 286
           S  P+ +T  P  P    S  P   T   T++  N       T++   +     ++ +  
Sbjct: 154 STSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKE-----TTVETKETTTTNKQTSTD 206

Query: 287 GGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPL 346
           G    TS   T      S   ++P +  +    P       GP+        TP    P 
Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA------LTTPKEPTPT 260

Query: 347 STSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVA 406
           +      T    PTP    ++ + P +  P    + P  P  P+  +    +    +  A
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA 320

Query: 407 TLTMTDRVPSPLSTVVST 424
             T  +  P+   +  +T
Sbjct: 321 PTTTKEPAPTTTKSAPTT 338


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 104/438 (23%), Positives = 141/438 (32%), Gaps = 62/438 (14%)

Query: 30  QEPSP---RESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           +EP+P   +E     P    P T      ++T+        P P  P   A      P P
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 87  RAEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTK 145
                P   T    A T   P   +     P AP   A T+ K E  P     P    TK
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTK 471

Query: 146 PPGATSR----PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
            P  T+     PTT     TT + P P           S P  P     + +KE      
Sbjct: 472 EPSPTTPKEPAPTTTKSAPTTTKEPAP-------TTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 202 PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQT--VAATTVP 259
               P   K+P              +   EP+  TP+ P    +  P P T    A T P
Sbjct: 525 KEPAPTTPKKP------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572

Query: 260 SNTSWAPT---------------TTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS 304
             T  APT               TT   PA   P           T T+       T  +
Sbjct: 573 KET--APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630

Query: 305 GAPVSP-QAAPVPSQRPHHGDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPA 362
            AP +P + AP   + P    P++  P+        TP  + P +      T    P P 
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690

Query: 363 AF---------DTSVSAPSQGIPQG-ASTTPQ--APTHPSRVSESTISGAKEETV-ATLT 409
                       T+   P+   P+G A TTP+  APT P   + +T  G    T+     
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750

Query: 410 MTDRVPSPLSTVVSTATG 427
            T + P+P     +T  G
Sbjct: 751 TTPKKPAPKELAPTTTKG 768



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 95/426 (22%), Positives = 139/426 (32%), Gaps = 42/426 (9%)

Query: 30  QEPSPR--ESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
           +EP+P   +S    P    P T  +AP +           P P  P   A      P P 
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382

Query: 88  AEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTKP 146
                PT        T   P   +     P  P     T+ K       + APT      
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST- 205
           P A  +P    P+      P+ P  +     + + P  PAP     +    +   P++T 
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 206 --PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS 263
             P   K P            + +   EP+  TP+ P       P P T       +   
Sbjct: 503 SAPTTPKEP------------SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 550

Query: 264 WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHH 322
            APTTT   PA   P  +  A       T+   T   T     P +P+  AP   ++P  
Sbjct: 551 PAPTTTK-KPAPTTP--KEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601

Query: 323 GDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP-QGAS 380
             P++  P+  +     TP    P +  +        P P    T+   P+   P + A 
Sbjct: 602 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAP 657

Query: 381 TTPQ--APTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
           TTP+  APT P   + +T+      T       +  P+      ST          PA T
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK------PAPT 711

Query: 439 WKPGTA 444
              GTA
Sbjct: 712 TPKGTA 717



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 82/357 (22%), Positives = 121/357 (33%), Gaps = 39/357 (10%)

Query: 45  TPPGTMVTAPH---SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
           T P T  T  +   +S + T+   + P P  PP+   +   + T   E        +T+ 
Sbjct: 193 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE--------TTVE 244

Query: 102 ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              T   ++ + + G      A  +   E       APT  +   P   +  TT  P  T
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 304

Query: 162 TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYK 221
           T + P P       +     P P        + +        S P   K P         
Sbjct: 305 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------- 355

Query: 222 GNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTV-AATTVPSNTSWAPTTTSLGPAKDKPGL 280
                +   EP+  TP+ P    +  P P T  +A T P     APTT    P K  P  
Sbjct: 356 ---APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTT----PKKPAPTT 406

Query: 281 RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDP-QDGPSHSDSWLTVT 339
            +      +  T +  TP  T    AP + + AP   + P    P +  P+        T
Sbjct: 407 PKEP----APTTPKEPTP-TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461

Query: 340 PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSEST 396
           P    P +T     T    P P    T+ SAP+       +TT  APT P   S +T
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 96/401 (23%), Positives = 128/401 (31%), Gaps = 59/401 (14%)

Query: 30  QEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE 89
           +EPSP  + +  P+ TP     T P             P P  P   A      P P   
Sbjct: 509 KEPSPTTTKEPAPT-TPKEPAPTTPKK-----------PAPTTPKEPAPTTPKEPAPTTT 556

Query: 90  GHPPTHTISTIAATV---TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
             P   T    A T    TAP +   L+         TT  KP      + APT      
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ-RGRNPSS- 204
           P     P    P+      P+ P  +       + P  PAP     +     +G  P++ 
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676

Query: 205 ---TPLGQKRPLGKIFQ---IYKGNFTGSVEPEPST------LTPRTPLWGYSSSPQPQT 252
               P   K+P  K        +   T   +P P+T       TP+ P       P P T
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 736

Query: 253 VAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP-Q 311
              T   +    APTT    P K  P         G T T+       T    AP +P +
Sbjct: 737 PKGTAPTTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792

Query: 312 AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAP 371
            AP   ++P                  TP T  P  T+S V T  T   P     S   P
Sbjct: 793 PAPTTPKKP---------------APTTPETPPP--TTSEVSTPTTTKEPTTIHKS---P 832

Query: 372 SQGIPQ-GASTTPQA----PTHPSRVSESTISGAKEETVAT 407
            +  P+  A  TP+A    P  P   +  T +  K E   T
Sbjct: 833 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 133/426 (31%), Gaps = 76/426 (17%)

Query: 33   SPRESLQVLPSGTPPGTMVT--------------APHSSTRHTSVVMLTPNPDGPPSQAA 78
            +P+E+    P GT P T+                AP ++   TS     P P  P   A 
Sbjct: 659  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 79   APMATPTPRAEGHP-PTHTISTIAATVTAPHSESSLSTGPAPAA-------MATTSSKPE 130
                 P P     P PT    T   T+  P   +     P   A        +TTS KP 
Sbjct: 719  TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP- 777

Query: 131  GRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGH 190
                   APT      P  T+  T   P  TT + P P           + P  P P   
Sbjct: 778  -------APT-----TPKETAPTTPKEPAPTTPKKPAP-----------TTPETPPP--- 811

Query: 191  SRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQP 250
                      +  STP   K P        +     S EP P  L          +SP+ 
Sbjct: 812  --------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL---------ENSPKE 854

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP 310
              V  T  P+ T    TTT    AKDK    R  +    T T+       TA +    + 
Sbjct: 855  PGVPTTKTPAATKPEMTTT----AKDKT-TERDLRTTPETTTAAPKMTKETATTTEKTTE 909

Query: 311  QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA 370
                  + +      QD      + L  T    +  +T   + T      P       + 
Sbjct: 910  SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP----EETAK 965

Query: 371  PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL 430
            P        +TTP+ P  P++  +   S  K +T+  +      P+P     +    N  
Sbjct: 966  PKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024

Query: 431  NRLVPA 436
            +R+  A
Sbjct: 1025 SRIAEA 1030



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 67/342 (19%), Positives = 110/342 (32%), Gaps = 83/342 (24%)

Query: 144 TKPPGATSRPTTAPP-------RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
           T PP +   P   PP       ++TT+R P+PP   +      S  +          +  
Sbjct: 70  TSPPSSKKAP---PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 126

Query: 197 QRGRNPSSTPLGQK----------RPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSS 246
               + SS+   +K          R L K  ++ K N     + +P   TP+ P+   + 
Sbjct: 127 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-KDNKKNRTKKKP---TPKPPVVDEAG 182

Query: 247 S---------PQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGL----------------- 280
           S           P T  +TT  +  S +P  T+  P   +P L                 
Sbjct: 183 SGLDNGDFKVTTPDT--STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 240

Query: 281 ------------RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG 328
                       ++ +  G    TS   T      S   ++P +  +    P       G
Sbjct: 241 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300

Query: 329 PSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP---QGASTTPQ- 384
           P+        TP    P +      T    PTP    ++ + P +  P   + A TTP+ 
Sbjct: 301 PA------LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354

Query: 385 ---------APTHPSRVSESTISGAKEETVATLTMTDRVPSP 417
                    APT P   + +T       T  +   T + P+P
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 104/438 (23%), Positives = 141/438 (32%), Gaps = 62/438 (14%)

Query: 30  QEPSP---RESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           +EP+P   +E     P    P T      ++T+        P P  P   A      P P
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 87  RAEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTK 145
                P   T    A T   P   +     P AP   A T+ K E  P     P    TK
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK-EPAPTTPKEPAPTTTK 512

Query: 146 PPGATSR----PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
            P  T+     PTT     TT + P P           S P  P     + +KE      
Sbjct: 513 EPSPTTPKEPAPTTTKSAPTTTKEPAP-------TTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 202 PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQT--VAATTVP 259
               P   K+P              +   EP+  TP+ P    +  P P T    A T P
Sbjct: 566 KEPAPTTPKKP------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613

Query: 260 SNTSWAPT---------------TTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS 304
             T  APT               TT   PA   P           T T+       T  +
Sbjct: 614 KET--APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671

Query: 305 GAPVSP-QAAPVPSQRPHHGDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPA 362
            AP +P + AP   + P    P++  P+        TP  + P +      T    P P 
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731

Query: 363 AF---------DTSVSAPSQGIPQG-ASTTPQ--APTHPSRVSESTISGAKEETV-ATLT 409
                       T+   P+   P+G A TTP+  APT P   + +T  G    T+     
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791

Query: 410 MTDRVPSPLSTVVSTATG 427
            T + P+P     +T  G
Sbjct: 792 TTPKKPAPKELAPTTTKG 809



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 95/426 (22%), Positives = 139/426 (32%), Gaps = 42/426 (9%)

Query: 30  QEPSPR--ESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR 87
           +EP+P   +S    P    P T  +AP +           P P  P   A      P P 
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423

Query: 88  AEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTKP 146
                PT        T   P   +     P  P     T+ K       + APT      
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSST- 205
           P A  +P    P+      P+ P  +     + + P  PAP     +    +   P++T 
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 206 --PLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS 263
             P   K P            + +   EP+  TP+ P       P P T       +   
Sbjct: 544 SAPTTPKEP------------SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 591

Query: 264 WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ-AAPVPSQRPHH 322
            APTTT   PA   P  +  A       T+   T   T     P +P+  AP   ++P  
Sbjct: 592 PAPTTTK-KPAPTTP--KEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642

Query: 323 GDPQD-GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP-QGAS 380
             P++  P+  +     TP    P +  +        P P    T+   P+   P + A 
Sbjct: 643 TTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP----TTPKEPAPTTPKEPAP 698

Query: 381 TTPQ--APTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGT 438
           TTP+  APT P   + +T+      T       +  P+      ST          PA T
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK------PAPT 752

Query: 439 WKPGTA 444
              GTA
Sbjct: 753 TPKGTA 758



 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 82/357 (22%), Positives = 121/357 (33%), Gaps = 39/357 (10%)

Query: 45  TPPGTMVTAPH---SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
           T P T  T  +   +S + T+   + P P  PP+   +   + T   E        +T+ 
Sbjct: 234 TTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE--------TTVE 285

Query: 102 ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              T   ++ + + G      A  +   E       APT  +   P   +  TT  P  T
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 345

Query: 162 TRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYK 221
           T + P P       +     P P        + +        S P   K P         
Sbjct: 346 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------- 396

Query: 222 GNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTV-AATTVPSNTSWAPTTTSLGPAKDKPGL 280
                +   EP+  TP+ P    +  P P T  +A T P     APTT    P K  P  
Sbjct: 397 ---APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTT----PKKPAPTT 447

Query: 281 RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDP-QDGPSHSDSWLTVT 339
            +      +  T +  TP  T    AP + + AP   + P    P +  P+        T
Sbjct: 448 PKEP----APTTPKEPTP-TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502

Query: 340 PGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSEST 396
           P    P +T     T    P P    T+ SAP+       +TT  APT P   S +T
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 96/401 (23%), Positives = 128/401 (31%), Gaps = 59/401 (14%)

Query: 30  QEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE 89
           +EPSP  + +  P+ TP     T P             P P  P   A      P P   
Sbjct: 550 KEPSPTTTKEPAPT-TPKEPAPTTPKK-----------PAPTTPKEPAPTTPKEPAPTTT 597

Query: 90  GHPPTHTISTIAATV---TAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP 146
             P   T    A T    TAP +   L+         TT  KP      + APT      
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657

Query: 147 PGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ-RGRNPSS- 204
           P     P    P+      P+ P  +       + P  PAP     +     +G  P++ 
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717

Query: 205 ---TPLGQKRPLGKIFQ---IYKGNFTGSVEPEPST------LTPRTPLWGYSSSPQPQT 252
               P   K+P  K        +   T   +P P+T       TP+ P       P P T
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 777

Query: 253 VAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP-Q 311
              T   +    APTT    P K  P         G T T+       T    AP +P +
Sbjct: 778 PKGTAPTTLKEPAPTT----PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833

Query: 312 AAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAP 371
            AP   ++P                  TP T  P  T+S V T  T   P     S   P
Sbjct: 834 PAPTTPKKP---------------APTTPETPPP--TTSEVSTPTTTKEPTTIHKS---P 873

Query: 372 SQGIPQ-GASTTPQA----PTHPSRVSESTISGAKEETVAT 407
            +  P+  A  TP+A    P  P   +  T +  K E   T
Sbjct: 874 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 133/426 (31%), Gaps = 76/426 (17%)

Query: 33   SPRESLQVLPSGTPPGTMVT--------------APHSSTRHTSVVMLTPNPDGPPSQAA 78
            +P+E+    P GT P T+                AP ++   TS     P P  P   A 
Sbjct: 700  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 79   APMATPTPRAEGHP-PTHTISTIAATVTAPHSESSLSTGPAPAA-------MATTSSKPE 130
                 P P     P PT    T   T+  P   +     P   A        +TTS KP 
Sbjct: 760  TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP- 818

Query: 131  GRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGH 190
                   APT      P  T+  T   P  TT + P P           + P  P P   
Sbjct: 819  -------APT-----TPKETAPTTPKEPAPTTPKKPAP-----------TTPETPPP--- 852

Query: 191  SRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQP 250
                      +  STP   K P        +     S EP P  L          +SP+ 
Sbjct: 853  --------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL---------ENSPKE 895

Query: 251  QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSP 310
              V  T  P+ T    TTT    AKDK    R  +    T T+       TA +    + 
Sbjct: 896  PGVPTTKTPAATKPEMTTT----AKDKT-TERDLRTTPETTTAAPKMTKETATTTEKTTE 950

Query: 311  QAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA 370
                  + +      QD      + L  T    +  +T   + T      P       + 
Sbjct: 951  SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP----EETAK 1006

Query: 371  PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL 430
            P        +TTP+ P  P++  +   S  K +T+  +      P+P     +    N  
Sbjct: 1007 PKDRATNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065

Query: 431  NRLVPA 436
            +R+  A
Sbjct: 1066 SRIAEA 1071



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 67/342 (19%), Positives = 110/342 (32%), Gaps = 83/342 (24%)

Query: 144 TKPPGATSRPTTAPP-------RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
           T PP +   P   PP       ++TT+R P+PP   +      S  +          +  
Sbjct: 111 TSPPSSKKAP---PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 167

Query: 197 QRGRNPSSTPLGQK----------RPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSS 246
               + SS+   +K          R L K  ++ K N     + +P   TP+ P+   + 
Sbjct: 168 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKV-KDNKKNRTKKKP---TPKPPVVDEAG 223

Query: 247 S---------PQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGL----------------- 280
           S           P T  +TT  +  S +P  T+  P   +P L                 
Sbjct: 224 SGLDNGDFKVTTPDT--STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 281

Query: 281 ------------RRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG 328
                       ++ +  G    TS   T      S   ++P +  +    P       G
Sbjct: 282 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341

Query: 329 PSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP---QGASTTPQ- 384
           P+        TP    P +      T    PTP    ++ + P +  P   + A TTP+ 
Sbjct: 342 PA------LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395

Query: 385 ---------APTHPSRVSESTISGAKEETVATLTMTDRVPSP 417
                    APT P   + +T       T  +   T + P+P
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 93/362 (25%), Positives = 129/362 (35%), Gaps = 70/362 (19%)

Query: 38  LQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTI 97
           LQ LPS  P   + T P  +    ++  L   P  P S   +P+ATP+P+A      H +
Sbjct: 603 LQGLPS-PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661

Query: 98  STIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAP 157
               +   +P  ++  S  PA   ++ +++ P   P   AAP   L  PP   + P  +P
Sbjct: 662 QAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSP 718

Query: 158 PRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIF 217
             T   + P P  +           VPP+P             +PS+TP  +  PL    
Sbjct: 719 SATPPPQAPPPLAA-------PPLQVPPSP-------PASPPMSPSATPPPRVPPLLAAP 764

Query: 218 QIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDK 277
            +        V P P    P +PL    + P PQ   A   P      P      P    
Sbjct: 765 PL-------QVPPSPPASLPMSPL----AKPPPQAPPALATP------PLQALPSPPASF 807

Query: 278 PGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLT 337
           P                G  P + +AS  P+SP A P P   P    P          L 
Sbjct: 808 P----------------GQAPFSPSAS-LPMSPLATPPPQAPPVLAAP----------LL 840

Query: 338 VTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTI 397
             P    P   +S    A   P     DTSVS P   +    +  P  P  PSR   ST+
Sbjct: 841 QVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTL----ALAPGPPPPPSRSPSSTL 892

Query: 398 SG 399
           SG
Sbjct: 893 SG 894



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 100/371 (26%), Positives = 130/371 (35%), Gaps = 82/371 (22%)

Query: 32  PSPRESLQVLPSGTPPGTMVT-----APHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           P P  +   LP+  PP   +      AP S +   S+  L   P  PPSQA   M TP  
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377

Query: 87  RAEGHPPTHTISTIAATVTAPHS--ESSLSTGPAPAAMATTSSKPE-GRPRGQAAPTILL 143
           +A   PP  ++ TI   +  PHS    SL   P+P A+++  +    G P  QA  +  L
Sbjct: 378 QA---PP--SLQTI-PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS-FL 430

Query: 144 TKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPS 203
           T  P  T    T+P R  +  P  PP                AP     S   Q   +P+
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPP--------------LQAPLSLPASPPLQTSLSPA 476

Query: 204 STPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSS-SPQPQTVAATTVPSNT 262
            +PL                        P T+ P   L   +S SPQ    +    P  T
Sbjct: 477 VSPLS----------------------SPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514

Query: 263 --SWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRP 320
             S AP +    PA                  S    P     S AP   Q A  P   P
Sbjct: 515 QSSLAPPSLQTPPA------------------SLTTPPLENLPSLAPPPLQTASAPLTTP 556

Query: 321 HHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQG-- 378
           H   P   P+        +P T+ P  T S + T    P P A     S P QG+P    
Sbjct: 557 HLETP-PCPAPCPLQAPPSPLTTPPPETPSSIAT----PPPQAPPALASPPLQGLPSPPL 611

Query: 379 ---ASTTPQAP 386
              A+  PQAP
Sbjct: 612 SPLATPPPQAP 622



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 100/423 (23%), Positives = 140/423 (33%), Gaps = 72/423 (17%)

Query: 43  SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           SG  PGT   A    +R     +  P P        AP A P P  EG  P  ++S+ + 
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRP--------APSARPRPPTEG--PRKSVSSASE 214

Query: 103 TVTAPHSES-----------------SLSTGPAP-AAMATTSSKPEGRPRGQAAPTILLT 144
             T   S +                 SLS+   P ++ A +     G PR  A P+    
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 145 KPPGATSRPTTAPPRTTTRRPPRP----PGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGR 200
           K   A   P   PPR        P    P ++   +G  +RPVPP     +         
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334

Query: 201 NPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPS 260
            P +TPL    P            + S  P   TL P  P    S +P   T      P 
Sbjct: 335 PPLATPLPLAPP------------SPSAPPSLQTL-PSPPATPPSQAPPSMTTPPMQAPP 381

Query: 261 NTSWAPTT----TSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA--SGAPVSPQAAP 314
           +    P      +   P+   P    A     +T +    T  AT +  + +P   QA+ 
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441

Query: 315 VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
               RP    P   P  +   L  +P    PL TS    + A  P  +        P Q 
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASP----PLQTS---LSPAVSPLSSPLTIH---PLQA 491

Query: 375 IPQGASTTPQAPTH-----PSRVSESTISGAKEETVATLT------MTDRVPSPLSTVVS 423
           +   AS +PQAP       P     S    + +   A+LT      +    P PL T  +
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551

Query: 424 TAT 426
             T
Sbjct: 552 PLT 554



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 101/367 (27%), Positives = 126/367 (34%), Gaps = 77/367 (20%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH 91
            PSP  S  + PS TPP      P +     +  +  P P  P S   +P ATP PR    
Sbjct: 708  PSPPASPPMSPSATPP------PQAPPPLAAPPLQVP-PSPPASPPMSPSATPPPRV--- 757

Query: 92   PPTHTISTIAATVTAPHS--ESSLSTGP--APAAMAT-----TSSKPEGRPRGQA--APT 140
            PP      +    + P S   S L+  P  AP A+AT       S P   P GQA  +P+
Sbjct: 758  PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPS 816

Query: 141  ILLTKPPGATSRPTTAPP---RTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQ 197
              L   P AT  P  APP       + PP PP S    A    RP  P P          
Sbjct: 817  ASLPMSPLATP-PPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLT 873

Query: 198  RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT 257
                P   P   + P   +        + S    P  L       GY S P+    AA +
Sbjct: 874  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR------GYDSGPEGG--AAAS 925

Query: 258  VPSNTSWA---PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAP 314
             P +   A   P   S GPA   P L                     A  GAP +P   P
Sbjct: 926  PPPDAELAACHPAAWSRGPA---PPL---------------------AFRGAPGAPLPWP 961

Query: 315  VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
                      P  GP  +D   T+   T  P S +        GP+P    TS    + G
Sbjct: 962  ----------PATGPGSADGLCTIYE-TEGPESATPAPGALDPGPSPG---TSGGKAAAG 1007

Query: 375  IPQGAST 381
               GAS+
Sbjct: 1008 AGAGASS 1014



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 85/348 (24%), Positives = 118/348 (33%), Gaps = 46/348 (13%)

Query: 74  PSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEG-R 132
           P+  A  + TP P     PP             P + ++L    A  A+     KP   R
Sbjct: 17  PAARAPGLLTPRPPGSPRPPP------------PVTPAALRVLGAAGAVGR---KPLAER 61

Query: 133 PRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSR 192
             G    TI  + P    +R      R    RPP      R     ++ P P +  G + 
Sbjct: 62  AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121

Query: 193 SKE-----GQRGRNPS---STPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPR------ 238
                   GQ+G   S   +   G+     K   +  G    +  P P T +P       
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181

Query: 239 -------TPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
                   P    S+ P+P T       S+ S   TT     A+ +P      Q   S  
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241

Query: 292 TSQGGTPDATAASGAPV---SPQAAPVPSQRPHHG-----DPQDGPSHSDSWLTVTPGTS 343
            S   TP ++ A   P    +P+A   PSQ    G      PQ  P   D+   + P +S
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 344 RPLSTSSGVFTAATG-PTPAAFDTSVSAPSQGIPQGASTTPQAPTHPS 390
            PL+T S   T A   P P    T + A     P  A+  P AP  PS
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS 349



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 54/205 (26%), Positives = 70/205 (34%), Gaps = 51/205 (24%)

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTF 291
           P  LTPR P  G    P P T AA  V           + G    KP   RA   GG+T 
Sbjct: 22  PGLLTPRPP--GSPRPPPPVTPAALRVLG---------AAGAVGRKPLAERAGGIGGATI 70

Query: 292 ---------TSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPG- 341
                    T   GT     AS  P S +    P  +     P   P  +    T  PG 
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG--TTRPGP 128

Query: 342 -------------------TSRP--LSTSSGVFTAATGPTPAAFDTSVSAPSQ------G 374
                              T  P   + S+G     +GPTP     +++  S+      G
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 375 IPQGA-STTPQAPTHPSRVSESTIS 398
           +P+ A S  P+ PT   R S S+ S
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSAS 213


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 98/440 (22%), Positives = 146/440 (33%), Gaps = 89/440 (20%)

Query: 14  SFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDG- 72
           +F L  A   +   ++  PS    L+ L     P ++   P S+   T+  +  P     
Sbjct: 158 TFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNL 217

Query: 73  -PP---SQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSK 128
            PP   SQ+  P   P+P  + +PPT  +  I                PAP+ +  T   
Sbjct: 218 LPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLI----------------PAPSMVPATD-- 259

Query: 129 PEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPG 188
                          TK P      TT  P+ T+   P P  S   G  N+S   P AP 
Sbjct: 260 ---------------TKAPPTLQAETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPA 304

Query: 189 GHSRS-----------KEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTP 237
             S S           K  + G  P    +    P              + +P  S++ P
Sbjct: 305 ASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGP 364

Query: 238 RT----PLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGP---------AKDKP----GL 280
                 P   +  +  P T   TT P  T  A  T+++ P         +  KP    G+
Sbjct: 365 PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 424

Query: 281 RRAAQGGGSTFTSQG---------GTPDATAASGAPV--------SPQAAPVPSQRPHHG 323
              +    ST TS           G P A+AAS  P          P A P  +      
Sbjct: 425 NSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFS 484

Query: 324 D--PQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAST 381
              P   P+ + S      G    L+TS+     AT   P    ++ S P+  IP G+S 
Sbjct: 485 QSLPTAVPTATSSSAADFSGFGSTLATSA----PATSSQPTLTFSNTSTPTFNIPFGSSA 540

Query: 382 TPQAPTHPSRVSESTISGAK 401
               P++P    +     A+
Sbjct: 541 KSPLPSYPGANPQPAFGAAE 560



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 94/370 (25%), Positives = 137/370 (37%), Gaps = 35/370 (9%)

Query: 56  SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE---GHPPTHTISTIAATVTAPHSESS 112
           S+T  T+     P   G P QA+A   TP   +    G PP      +  T T      S
Sbjct: 433 STTTSTATAASQPFLFGAP-QASAASFTPAMGSIFQFGKPPA-----LPTTTTVTTFSQS 486

Query: 113 LSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSS 172
           L   P     AT+SS  +    G      L T  P  +S+PT     T+T     P GSS
Sbjct: 487 L---PTAVPTATSSSAADFSGFGST----LATSAPATSSQPTLTFSNTSTPTFNIPFGSS 539

Query: 173 RKGAGNSSRPVPPAPGGHSRSKEG-QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPE 231
            K       P+P  PG + +   G   G+ P +         G  F  +  +   +  P 
Sbjct: 540 AKS------PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSF-TFGNSAAPAAAPT 592

Query: 232 PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP--GLRRAAQGGGS 289
           P+  +    +  +  +P   T    T  +    A  +    PA  +P  G   A    G+
Sbjct: 593 PAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGA 652

Query: 290 TFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTS 349
             +S  G    TA+SG+  S   +  PS     G      S S      TPG+    S +
Sbjct: 653 ATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGS----SAT 708

Query: 350 SGVFTAATGPTPAAFDTSVSAP-SQGIPQGA-STTPQAPTHPSRVSESTISGAKEETVAT 407
           +G F+   G + +   T+ S P + G+ Q A  TT Q+      V  +T S       AT
Sbjct: 709 TGAFSFGAGQSGS---TATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTAT 765

Query: 408 LTMTDRVPSP 417
            T     P+P
Sbjct: 766 PTFGLNTPAP 775


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 114/517 (22%), Positives = 168/517 (32%), Gaps = 122/517 (23%)

Query: 14  SFLLILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDG- 72
           +F L  A T +   ++  PS    L+ L     P ++   P S+   T+  +  P     
Sbjct: 309 TFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSL 368

Query: 73  -PP---SQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSK 128
            PP   SQ+  P   P+P  +  PPT  +  I                PAP+ +  T   
Sbjct: 369 LPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLI----------------PAPSMVPATD-- 410

Query: 129 PEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPG 188
                          TK P      T   P+ T+   P P  S   G  N+S   P AP 
Sbjct: 411 ---------------TKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPA 455

Query: 189 GHSRS-----------KEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTP 237
             S S           K  + G  P    +    P              + +P  S++ P
Sbjct: 456 ASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGP 515

Query: 238 RT----PLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGP---------AKDKP----GL 280
                 P   +  +  P T   TT P  T  A  T+++ P         +  KP    G+
Sbjct: 516 PASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGI 575

Query: 281 RRAAQGGGSTFTSQG---------GTPDATAASGAPV--------SPQAAPVPSQRPHHG 323
              +    ST TS           G P A+AAS  P          P A P  +      
Sbjct: 576 NSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFS 635

Query: 324 D--PQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAST 381
              P   P+ + S      G    L+TS+     AT   P    ++ S P+  IP G+S 
Sbjct: 636 QSLPTAVPTATSSSAADFSGFGSTLATSA----PATSSQPTLTFSNTSTPTFNIPFGSSA 691

Query: 382 TPQAPTHPSRVSESTISGAKEE---------------------TVATLTMTDRVPSPLST 420
               P++P    +     A+ +                     + A    T   P+P ST
Sbjct: 692 KSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPAST 751

Query: 421 VVSTATGNFLNRLVPAGTWKP--GTAGNISHVAEGDK 455
           +          ++VPA    P   T G  +H A G K
Sbjct: 752 I----------KIVPAHVPTPIQPTFGGATHSAFGLK 778



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 98/376 (26%), Positives = 137/376 (36%), Gaps = 45/376 (11%)

Query: 56  SSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE---GHPPTHTISTIAATVTAPHSESS 112
           S+T  T+     P   G P QA+A   TP   +    G PP      +  T T      S
Sbjct: 584 STTTSTATAASQPFLFGAP-QASAASFTPAMGSIFQFGKPPA-----LPTTTTVTTFSQS 637

Query: 113 LSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSS 172
           L   P     AT+SS  +    G      L T  P  +S+PT     T+T     P GSS
Sbjct: 638 L---PTAVPTATSSSAADFSGFGST----LATSAPATSSQPTLTFSNTSTPTFNIPFGSS 690

Query: 173 RKGAGNSSRPVPPAPGGHSRSKEGQ-RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPE 231
            K       P+P  PG + +   G   G+ P +         G  F      F  S  P 
Sbjct: 691 AKS------PLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSF-----TFGNSAAPA 739

Query: 232 PSTLTPRTP------LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKP--GLRRA 283
           P+T     P      +  +  +P   T    T  +    A  +    PA  +P  G   A
Sbjct: 740 PATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTA 799

Query: 284 AQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTS 343
               G+  +S  G    TA+SG+  S   +  PS     G      S S      TPG+ 
Sbjct: 800 VFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGS- 858

Query: 344 RPLSTSSGVFTAATGPTPAAFDTSVSAP-SQGIPQGA-STTPQAPTHPSRVSESTISGAK 401
              S ++G F+   G + +   T+ S P + G+ Q A  TT Q+      V  +T S   
Sbjct: 859 ---SATTGAFSFGAGQSGS---TATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPV 912

Query: 402 EETVATLTMTDRVPSP 417
               AT T     P+P
Sbjct: 913 FGGTATPTFGQNTPAP 928


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 86/341 (25%), Positives = 119/341 (34%), Gaps = 40/341 (11%)

Query: 28  AIQEP-SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
           A Q P  P +   V+P+G  P    +   SS+   +V          PS A      P+P
Sbjct: 522 AFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTV----------PSSAGILEQGPSP 571

Query: 87  RAEGHPPTHTISTIAATVTAPHSESSLSTGP-APAAMATTSSKPEGRPRGQAAPTILLTK 145
             +G PP       AA      + S +++G   P A A +     G+P   A P+    +
Sbjct: 572 -GDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLR 630

Query: 146 PPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQR-GRNPSS 204
              A  +P  APP+     P  P G S  G       + P P   S S   Q  G+ P  
Sbjct: 631 R--AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQ 688

Query: 205 TPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLW----GYSSSPQPQTVAA----- 255
                +    + +            P P   T  TPL          P P  + +     
Sbjct: 689 PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLE 748

Query: 256 --TTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPD-ATAASGAPVSPQA 312
             +  P  T   P+T  LG  K  P L        +  T  GG P+ A   +G    P+ 
Sbjct: 749 QPSHTPPQTPTPPSTPPLG--KQNPSL-------PAPQTLAGGNPETAQPHAGTLPRPRP 799

Query: 313 APVPSQRPHHGDPQDGP---SHSDSWLTVTPGTSRPLSTSS 350
            P P  RP    P   P   S  DS LT T  T+  + T S
Sbjct: 800 VPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDS 840



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 76/308 (24%), Positives = 101/308 (32%), Gaps = 75/308 (24%)

Query: 153 PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVP---------PAPGGHSRSKEGQR----- 198
           P T         P  PP SSR  + +    VP         P+PG  S  K         
Sbjct: 528 PPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAV 587

Query: 199 ---GRNPSSTPLGQKRPLGKI--FQIYKGNFTGSVEPEPSTL-------TPRTPLWGYSS 246
              GRN S    GQ +P       Q+  G    +  P P TL        P  P  G   
Sbjct: 588 PAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPP 647

Query: 247 SPQP--QTVAATTV-PSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAA 303
              P  Q+ + T+  P + S  P T S  P     G                G P A + 
Sbjct: 648 PGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTG-------------QPPGQPSAPSQ 694

Query: 304 SGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAA 363
             AP    ++  P Q P+H  PQ  P+ +   +   P +  P             P P A
Sbjct: 695 LSAPRRYSSSLSPIQAPNHPPPQP-PTQATPLMHTKPNSQGP-------------PNPMA 740

Query: 364 FDTSVSAPSQGIPQGASTTPQAPT----------HPSRVSESTISGAKEET----VATLT 409
             +       G+ Q + T PQ PT          +PS  +  T++G   ET      TL 
Sbjct: 741 LPSE-----HGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLP 795

Query: 410 MTDRVPSP 417
               VP P
Sbjct: 796 RPRPVPKP 803


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 109/438 (24%), Positives = 149/438 (34%), Gaps = 86/438 (19%)

Query: 30  QEPSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE 89
           Q PS  + LQ L +   P T V                P     PS    P  +    A 
Sbjct: 47  QGPSDSQILQGLCASEGPSTSVL---------------PTSAEGPSTFVPPTISEASSAS 91

Query: 90  GHPPTHTISTIAATVTAPHSESSLSTGPAPA-----AMATTSSKPEGRPRGQAAPTILLT 144
           G P   TIS    T   P     LST   P        + T +  EGR           +
Sbjct: 92  GQP---TISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNT---------S 139

Query: 145 KPPGATSRPTTAPPRTTTRRP----PRPPGSSRKGA-------GNSSRPVPPAPGGHSRS 193
           +PP ++  P+T+ P T +  P    P  PG     +       G S+  VP    G S S
Sbjct: 140 RPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTS 199

Query: 194 KEGQRGRNP-SSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQT 252
                G  P +S PL     L    Q        + +  PST  P T   G S+ P P T
Sbjct: 200 VLPTPGEGPGTSVPLAATEGLSTSVQ-------ATPDEGPSTSVPPTATEGLST-PVPPT 251

Query: 253 V---AATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVS 309
                +T+VP+     P+T+ L  A D   +      G  + TS    P AT      V 
Sbjct: 252 RDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSV--PPTATEGLSTSVQ 309

Query: 310 PQAA--------PVPSQRPHHGDPQDGPSHSDSWLTVTPG----------------TSRP 345
           P A         P P        P        + +  TPG                TS P
Sbjct: 310 PTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVP 369

Query: 346 LSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETV 405
            + S G  T+   PTP    +++  P+     G+S  P     PS +  S+ S  +  + 
Sbjct: 370 PTASDGSDTSVP-PTPGEGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSASVDRNPSK 428

Query: 406 ATLTMTDRVPSPLSTVVS 423
            +L +    PSP  T  S
Sbjct: 429 CSLVL----PSPRVTKAS 442



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 93/368 (25%), Positives = 130/368 (35%), Gaps = 48/368 (13%)

Query: 102 ATVTAPHS---ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPP 158
           A  TA +S   E      P   A    S  P+G    Q    +  ++ P  +  PT+A  
Sbjct: 16  AKATAHNSSWGEMQAPNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEG 75

Query: 159 RTTTRRPPRPPGSS-------RKGAGNSSRPVP----PAPGGHSRSK--------EGQRG 199
            +T   P     SS        +G G S  P P       G  + SK            G
Sbjct: 76  PSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEG 135

Query: 200 RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTV--AATT 257
           RN S  P   + P   +          +    PST  P TP  G S+S  P      +T+
Sbjct: 136 RNTSRPPTSSEEPSTSV--------PPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTS 187

Query: 258 VPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQ---AAP 314
           V       P+T+ L    + PG            TS   TPD   ++  P +     + P
Sbjct: 188 VVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTP 247

Query: 315 VPSQRPH------HGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSV 368
           VP  R           P +GPS S      + G S  L  + G  ++ + P  A    S 
Sbjct: 248 VPPTRDEGPSTSVPATPGEGPSTS-VLPAASDGQSISLVPTRGKGSSTSVPPTATEGLST 306

Query: 369 SA-PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATG 427
           S  P+ G  +G+ST+   PT    +S S    A EE   ++  T       ST V    G
Sbjct: 307 SVQPTAG--EGSSTS-VPPTPGGGLSTSVPPTATEELSTSVPPTP--GEGPSTSVLPIPG 361

Query: 428 NFLNRLVP 435
             L+  VP
Sbjct: 362 EGLSTSVP 369



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 59/210 (28%), Positives = 77/210 (36%), Gaps = 33/210 (15%)

Query: 19  LALTEALAFAIQE-PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQA 77
           LA TE L+ ++Q  P    S  V P+ T   +    P      ++ V  TP     PS +
Sbjct: 214 LAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEG--PSTS 271

Query: 78  AAPMAT--------PTPRAEGH----PPTHTISTIAATVTAPHSESSLSTGPAPAAMATT 125
             P A+        PT R +G     PPT T     +        SS S  P P    +T
Sbjct: 272 VLPAASDGQSISLVPT-RGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLST 330

Query: 126 SSKPEGR--------PRGQAAPTILLTKPPG---ATSRPTTAPPRTTTRRPPRPPGSSRK 174
           S  P           P     P+  +   PG   +TS P TA   + T  PP P      
Sbjct: 331 SVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTP------ 384

Query: 175 GAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
           G G S+   P AP G   S     G  PS+
Sbjct: 385 GEGASTLVQPTAPDGPGSSVLPNPGEGPST 414


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 105/436 (24%), Positives = 160/436 (36%), Gaps = 78/436 (17%)

Query: 48  GTMVTAPHSSTRHTSVVMLTPNP-----DGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           G   T  HSST HT  +   P+      + P S  ++P +T T      P + T S  + 
Sbjct: 13  GEESTTSHSSTTHT--ISSAPSTTSALVEEPTSYHSSPGSTATTH---FPDSSTTSGRSE 67

Query: 103 TVTAPHS-ESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
             TA HS + +  T   PA   T+    E      ++ ++  T  PG+T+ P  +   TT
Sbjct: 68  ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 127

Query: 162 TRRPPRPP------------GSSRKGAGNSSRP------------VPPAPGGHSRSKEGQ 197
               PR P            G S +   + SRP              P    HS +    
Sbjct: 128 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 187

Query: 198 RGRN-----PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTL---------------TP 237
            G       P+ST                G+   ++ P  +T                + 
Sbjct: 188 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 247

Query: 238 RTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGT 297
            T L+  S++      A+T V S+T  +P TT    +   PGL    QG  + F +    
Sbjct: 248 HTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPASSTSPGL----QGESTAFQTH--- 299

Query: 298 PDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAAT 357
           P +T  + +P S   APV     +H  P   P+      + T G S   ST       A+
Sbjct: 300 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSPDAS 358

Query: 358 GPTPAAFDTSVSAPSQGIPQGASTTPQAP--THPSRVSES-TISGAKEETV-------AT 407
           G TP    +S  + + G+ + +ST+   P  TH +   +S T SG  +E         +T
Sbjct: 359 GTTP----SSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST 414

Query: 408 LTMTDRVPSPLSTVVS 423
               D  PSP  T  +
Sbjct: 415 EATLDTTPSPPGTTAA 430



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 108/445 (24%), Positives = 162/445 (36%), Gaps = 53/445 (11%)

Query: 22  TEALAFAIQEPSPRESLQVLPSGTPPGTMVTA--PHSSTRHTSVVMLTPNPDGPPSQ--A 77
           T   AF     +P  S     S + PG+  T   P S+T        T +   P S   A
Sbjct: 163 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTA 222

Query: 78  AAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQA 137
            +P +T T  + G   T   S+  +T T    +S+ S+G   A+    SS   G PR   
Sbjct: 223 LSPGST-TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST--GSPRTTL 279

Query: 138 APTILLTKPPGATSRPTTAPPR-TTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
           +P    +  PG     T       +T   P PP ++       + PV  +   H      
Sbjct: 280 SPAS--STSPGLQGESTAFQTHPASTHTTPSPPSTA-------TAPVEESTTYH------ 324

Query: 197 QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP-LWGYSSSPQPQTVAA 255
              R+P STP             +  + T S   E ST+   +P   G + S    T + 
Sbjct: 325 ---RSPGSTPTTH----------FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 371

Query: 256 TTVPSNTSWA-PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAP 314
            +  S+TS + P +T      D       +Q   ++ +SQG T      + +P    AAP
Sbjct: 372 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAP 431

Query: 315 VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST-----SSGVFTAATGPTPAAFDTSVS 369
           V     +H  P   P+   S  + T G S   +T      S   TA  G T  A  +  S
Sbjct: 432 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKS 491

Query: 370 APSQGIPQGASTT--PQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATG 427
                 P+   TT  P + T      EST S ++  +  T         P    ++T   
Sbjct: 492 TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGQHWIAT--- 548

Query: 428 NFLNRLVPAGTWKPGTAGNISHVAE 452
              +  VP   +   T+G I H+ E
Sbjct: 549 ---HNTVPCRLY--NTSGRIYHLPE 568


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 96/399 (24%), Positives = 143/399 (35%), Gaps = 35/399 (8%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            PS    G     P + T   S    TP P   PS A+    TP P  +    T + ST  
Sbjct: 1574 PSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTD----TSSASTGD 1629

Query: 102  ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAP---- 157
             T     + SSLSTG A     T+   P     G A P  + +    +T   T  P    
Sbjct: 1630 TTPLPVTNASSLSTGHATPLHVTS---PSSASTGHATPLPVTSTSSASTGHATPLPVTGL 1686

Query: 158  ----PRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPL 213
                   TTR P     S+  G   +  PV       +         +PSS   G   PL
Sbjct: 1687 SSATTDDTTRLPVTDVSSASTGQA-TPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPL 1745

Query: 214  GKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTT----T 269
              +        TG   P P  +T  + +    ++P P T  ++    +T+  P T     
Sbjct: 1746 --LVTDASSASTGQATPLP--VTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSA 1801

Query: 270  SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGP 329
            S G A   P    ++   G   T+     DA++AS    +     +PS     G     P
Sbjct: 1802 STGQAIPLPVTSPSSASTGD--TTPLPVTDASSASTGDTTSLPVTIPSS-ASSGHTTSLP 1858

Query: 330  SHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHP 389
                S ++    TS  ++ +S V T  T P P     S S           TTP   T  
Sbjct: 1859 VTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSAST--------GDTTPLHVTDA 1910

Query: 390  SRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
            S VS    +     ++++ +  D  P P+++  S ++G+
Sbjct: 1911 SSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGH 1949



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 110/443 (24%), Positives = 162/443 (36%), Gaps = 51/443 (11%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            S    G     P +ST   S    TP P    S A+   ATP P         ++ST   
Sbjct: 2999 SSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTS----LSSVSTGDT 3054

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAP---TILLTKPPG-ATSRPTTAPP 158
            T     S SS STG A   + T +S       GQA P   T L +   G  T  P T+P 
Sbjct: 3055 TPLPVTSPSSASTGHATPLLVTDASSAS---TGQATPLPVTSLSSVSTGDTTPLPVTSPS 3111

Query: 159  RTTTRRP---PRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPL-- 213
              +T      P    SS      +S PV      ++         + SS+  G   PL  
Sbjct: 3112 SASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLV 3171

Query: 214  GKIFQIYKGNFTGSVEPEPSTLTP--RTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL 271
             +   +  G+ T  +  + S+ +    TPL  + +SP   +   TT    T  +  +T  
Sbjct: 3172 TETSSVSTGHATPLLVTDASSASTGHATPL--HVTSPSSASTGDTTPVPVTDTSSVSTGH 3229

Query: 272  GPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVP---SQRPHHGDPQDG 328
                   GL  A+ G     T++    D ++AS    + QA P+P   +     GD    
Sbjct: 3230 ATPLPVTGLSSASTGD----TTRLPVTDISSAS----TGQATPLPVTNTSSVSTGDTMPL 3281

Query: 329  PSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG----IP-------Q 377
            P  S S  +    T  P++++S   T    P P    TS S+ S G    +P        
Sbjct: 3282 PVTSPSSASTGHATPLPVTSTSSASTGHATPVPV---TSTSSASTGHTTPLPVTDTSSAS 3338

Query: 378  GASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL------N 431
               TTP   T PS  S    +       ++ +  D    P++   S +TG+         
Sbjct: 3339 TGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDT 3398

Query: 432  RLVPAGTWKPGTAGNISHVAEGD 454
              V  G   P    ++S V+ GD
Sbjct: 3399 SSVSTGHATPLPVTSLSSVSTGD 3421



 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 105/413 (25%), Positives = 154/413 (37%), Gaps = 51/413 (12%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHS-STRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEG 90
            P P  SL  + +G      VT+P S ST H S +++T       S A+   ATP P  + 
Sbjct: 1712 PLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTD-----ASSASTGQATPLPVTD- 1765

Query: 91   HPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGAT 150
               T ++ST  AT       SS ST        T  S       GQA P + +T P  A+
Sbjct: 1766 ---TSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSAS---TGQAIP-LPVTSPSSAS 1818

Query: 151  SRPTTAPPRT---------TTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
            +  TT  P T         TT  P   P S+  G   +S PV  A    +         +
Sbjct: 1819 TGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGH-TTSLPVTDASSVSTGHATSLLVTD 1877

Query: 202  PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSN 261
             SS   G   PL              V    S  T  T     + +    T  AT++P  
Sbjct: 1878 ASSVSTGDTTPL-------------PVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVT 1924

Query: 262  TSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPH 321
            +    ++ S G     P    ++   G T T    T  ++  +G   S       S    
Sbjct: 1925 SL---SSASTGDTTPLPVTSPSSASSGHT-TPLPVTDASSVPTGHATSLPVTDASSVSTG 1980

Query: 322  HGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAST 381
            H  P   P    S ++    T  P++ +S V T    P P    TS+S+ S G      T
Sbjct: 1981 HATPL--PVTDASSVSTGHATPLPVTDTSSVSTGQATPLPV---TSLSSASTG-----DT 2030

Query: 382  TPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLV 434
            TP   T  S  S    +     ++++++  D  P P+++  S +TG+    LV
Sbjct: 2031 TPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLV 2083



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 105/418 (25%), Positives = 159/418 (38%), Gaps = 59/418 (14%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP--RAEGHPPTHTIS-- 98
            S    G   + P +S    S    TP P   PS A++   TP P   A   P  H  S  
Sbjct: 1911 SSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLP 1970

Query: 99   -TIAATVTAPHSE-------SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGAT 150
             T A++V+  H+        SS+STG A     T +S       GQA P + +T    A+
Sbjct: 1971 VTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVS---TGQATP-LPVTSLSSAS 2026

Query: 151  SRPTTAPPRTTT------RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS 204
            +  TT  P T T      +  P P  S    +   + P+P                +PSS
Sbjct: 2027 TGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVT--------------SPSS 2072

Query: 205  TPLGQKRPL--GKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNT 262
               G   PL       +  G+ T  +  + S+++       + +     +   TT    T
Sbjct: 2073 ASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVT 2132

Query: 263  SWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHH 322
            S  P++ S G     P    ++   G   TS   T  ++A++G   S       S    H
Sbjct: 2133 S--PSSASTGDTTPLPVTDTSSVSTGHA-TSLPVTDTSSASTGHATSLPVTDTSSASTGH 2189

Query: 323  GDP---QDGPSHSDSWLTVTPGTSRPLSTSSG---------VFTAATGPTPAAFDTSVSA 370
              P    D  S S    T  P TS P S S+G           +A+TG       TS+S+
Sbjct: 2190 ATPLPVTDTSSASTGQATPLPVTS-PSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSS 2248

Query: 371  PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
             S G      TTP   T  S VS    +     ++++++  D  P P+++  S +TG+
Sbjct: 2249 ASTG-----DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGH 2301



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 107/428 (25%), Positives = 159/428 (37%), Gaps = 61/428 (14%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP------RAEGHP--- 92
            PS    G     P + T   S     P     PS A+   ATP P       + GH    
Sbjct: 2902 PSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPL 2961

Query: 93   PTHTISTIAATVTAP---HSESSLSTG-PAPAAMATTSSKPEGRPRGQAAPTILLTKPPG 148
            P  ++S+++   T P    S SS STG   P  +  TSS   G+     A  + +T    
Sbjct: 2962 PVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQ-----ATALPVTSTSS 3016

Query: 149  ATSRPTTAPPRTTT------RRPPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQ 197
            A++  TT  P T T      +  P P  S    +   + P+P      A  GH+      
Sbjct: 3017 ASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP---L 3073

Query: 198  RGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT 257
               + SS   GQ  PL           TG   P P T +P +   G+++S      ++ +
Sbjct: 3074 LVTDASSASTGQATPLP--VTSLSSVSTGDTTPLPVT-SPSSASTGHATSLPVTDTSSAS 3130

Query: 258  VPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGST-------------FTSQGGTP----DA 300
                TS   T TS     D   L        ST              ++   TP    DA
Sbjct: 3131 TGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDA 3190

Query: 301  TAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPT 360
            ++AS    +P     PS     GD    P    S  +V+ G + PL   +G+ +A+TG T
Sbjct: 3191 SSASTGHATPLHVTSPSS-ASTGDTTPVPVTDTS--SVSTGHATPLPV-TGLSSASTGDT 3246

Query: 361  PAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
                 T +S+ S G       TP   T+ S VS          + ++ +     P P+++
Sbjct: 3247 TRLPVTDISSASTG-----QATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTS 3301

Query: 421  VVSTATGN 428
              S +TG+
Sbjct: 3302 TSSASTGH 3309



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 106/434 (24%), Positives = 157/434 (36%), Gaps = 71/434 (16%)

Query: 41   LPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            +PS +  G     P +ST   S   +TP     PS A+    TP P       T + ST 
Sbjct: 3573 IPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTS----TSSASTG 3628

Query: 101  AATVTAPHSESSLSTG---PAPAAMATTSSKPEGRP----------RGQAAP---TILLT 144
             AT       SS+STG   P P   A+++S  +  P           GQA P   T L +
Sbjct: 3629 HATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS 3688

Query: 145  KPPGATS--RPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP 202
               G T+    T A   +T    P P       +   + P+P                +P
Sbjct: 3689 VSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVT--------------SP 3734

Query: 203  SSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNT 262
            SS   G   PL  +  +   + TG   P P T T         ++P P T  ++    +T
Sbjct: 3735 SSASTGHATPL-PVTGLSSAS-TGDTTPLPVTDTSSAST--RHATPLPVTDTSSASTDDT 3790

Query: 263  SWAPTT----TSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQ 318
            +  P T     S G A   P    ++   G T T    T  ++ ++G   S       S 
Sbjct: 3791 TRLPVTDVSSASTGHATPLPVTSTSSASTGDT-TPLPVTDTSSVSTGHATSLPVTSRSSA 3849

Query: 319  RPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVS--------A 370
               H  P   P    S ++    T  P++++S V T    P P    +S S         
Sbjct: 3850 STGHATPL--PVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPV 3907

Query: 371  PSQGIPQGASTTPQAPTHPSRVSE--------STISGAKEETVATLTMTD--------RV 414
             S        TTP   T+ S +S         ++ S A     +TL +TD          
Sbjct: 3908 TSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHAT 3967

Query: 415  PSPLSTVVSTATGN 428
            P PL+++ S +TG+
Sbjct: 3968 PLPLTSLSSVSTGD 3981



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 97/411 (23%), Positives = 158/411 (38%), Gaps = 43/411 (10%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHS-STRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEG 90
            P P  SL  + +G      VT+P S ST H + +++T       S A+   ATP P  + 
Sbjct: 1168 PLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDT-----SSASTGHATPLPVTDA 1222

Query: 91   HPPTHTISTIAAT---VTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
                 ++ST  AT   VT P + S+  T P P  +  TSS   G+     A ++L+T   
Sbjct: 1223 S----SVSTDHATSLPVTIPSAASTGHTTPLP--VTDTSSASTGQ-----ATSLLVTDTS 1271

Query: 148  GATSRPTTAPPRTTTRR-------PPRPPGSSRKGAGNSSR-PVPPAPGGHSRSKEGQRG 199
              ++  TT  P T+T         P      S    G+++  PV       +        
Sbjct: 1272 SVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPV 1331

Query: 200  RNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVP 259
             +PSS   G   PL     +   +   +    P  +T  +      ++P P T  ++   
Sbjct: 1332 TSPSSASTGDTTPL----PVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVST 1387

Query: 260  SNTSWAPTTT--SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPS 317
             +T+  P T+  S       P L        +   +     DA++ S    +     +PS
Sbjct: 1388 GDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPS 1447

Query: 318  QRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQ 377
                 G     P    S  +    TS  ++ +S V T  T P P    TS S+ S G   
Sbjct: 1448 AAST-GHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPV---TSTSSASTG--- 1500

Query: 378  GASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
                TP   T PS  S    +     ++++ +  D +P P+++  S +TG+
Sbjct: 1501 --HVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 97/419 (23%), Positives = 153/419 (36%), Gaps = 59/419 (14%)

Query: 32   PSPRESLQVLPSG-TPPGTMVTAPHSSTRHTSVVMLT-PNPDGPPSQAAAPMATPTPRAE 89
            P P  SL  + +G T P  +  A  +ST H + + +T P+          P+ +P+  + 
Sbjct: 3680 PLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAST 3739

Query: 90   GHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGA 149
            GH            VT   S S+  T P P    +++S     P       + +T    A
Sbjct: 3740 GH-------ATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATP-------LPVTDTSSA 3785

Query: 150  TSRPTTAPPRT------TTRRPPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQR 198
            ++  TT  P T      T    P P  S+   +   + P+P         GH+ S     
Sbjct: 3786 STDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLP-VT 3844

Query: 199  GRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTV 258
             R+ +ST      P+     +  G+ T    P P T           S+    T  AT +
Sbjct: 3845 SRSSASTGHATPLPVTDTSSVSTGHAT----PLPVT-----------STSSVSTGHATPL 3889

Query: 259  PSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQ 318
            P  +   P++ S G A   P    ++   G T        +A++ S    +P     PS 
Sbjct: 3890 PVTS---PSSASTGHATPVPVTSTSSASTGDTTPLP--VTNASSLSTGHATPLHVTSPSS 3944

Query: 319  RPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIP-- 376
                GD    P    S  +    T  PL++ S V T  T P P   DTS ++  Q  P  
Sbjct: 3945 ASR-GDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVT-DTSSASTGQATPLP 4002

Query: 377  -------QGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
                       TTP   T PS  S    +       ++++     P P+++  S +TG+
Sbjct: 4003 VTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGD 4061



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 108/453 (23%), Positives = 161/453 (35%), Gaps = 65/453 (14%)

Query: 17   LILALTEALAFAIQEPSPRESLQVLPSGTPPGTMVTAPHS-STRHTSVVMLT-------- 67
            L++  T +++     P P  S     +G      VT+P S ST H + + +T        
Sbjct: 1473 LLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG 1532

Query: 68   ---PNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMAT 124
               P P   PS A+    TP P  +      T  T    VT+P S S+  T P P    +
Sbjct: 1533 DTMPLPVTSPSSASTGDTTPLPVTDA-SSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTS 1591

Query: 125  TSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVP 184
            ++SK +  P       + +T P  A++  TT  P T T        SS      +  PV 
Sbjct: 1592 SASKGDTTP-------LPVTSPSSASTGHTTPLPVTDT--------SSASTGDTTPLPVT 1636

Query: 185  PAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPST--------LT 236
             A    +         +PSS   G   PL           TG   P P T         T
Sbjct: 1637 NASSLSTGHATPLHVTSPSSASTGHATPLP--VTSTSSASTGHATPLPVTGLSSATTDDT 1694

Query: 237  PRTPLWGYSS------SPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGST 290
             R P+   SS      +P P T  ++    +T+  P T+   P+    G         ++
Sbjct: 1695 TRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTS---PSSASTGHASPLLVTDAS 1751

Query: 291  FTSQG-GTPDATAASGAPVSPQAAPVPSQRPHHGDPQDG---PSHSDSWLTVTPGTSRPL 346
              S G  TP     + +  +  A P+P          D    P    S  +       P+
Sbjct: 1752 SASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPV 1811

Query: 347  STSSGVFTAATGPTPAAFDTSVSAPSQG--------IPQGAS---TTPQAPTHPSRVSES 395
            ++ S   T  T P P    T  S+ S G        IP  AS   TT    T  S VS  
Sbjct: 1812 TSPSSASTGDTTPLPV---TDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTG 1868

Query: 396  TISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
              +       ++++  D  P P++   S +TG+
Sbjct: 1869 HATSLLVTDASSVSTGDTTPLPVTDTNSASTGD 1901



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 97/405 (23%), Positives = 152/405 (37%), Gaps = 31/405 (7%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            PS    G     P +     S    TP P   PS A+    TP P  +    +    T  
Sbjct: 1542 PSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKG-DTTP 1600

Query: 102  ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              VT+P S S+  T P P    +++S  +  P      + L T    AT    T+P   +
Sbjct: 1601 LPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLST--GHATPLHVTSPSSAS 1658

Query: 162  T-RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP----SSTPLGQKRPLGKI 216
            T    P P  S+   +   + P+P    G S +      R P    SS   GQ  PL   
Sbjct: 1659 TGHATPLPVTSTSSASTGHATPLPVT--GLSSATTDDTTRLPVTDVSSASTGQATPLP-- 1714

Query: 217  FQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPT--TTSLGPA 274
                    TG   P P T +P +   G+ +SP   T A++      +  P   T+S+  A
Sbjct: 1715 VTSLSSVSTGDTTPLPVT-SPSSASTGH-ASPLLVTDASSASTGQATPLPVTDTSSVSTA 1772

Query: 275  KDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHH---GDPQDGPSH 331
               P          +  T++    D ++AS    + QA P+P   P     GD    P  
Sbjct: 1773 HATPLPVTGLSSASTDDTTRLPVTDVSSAS----TGQAIPLPVTSPSSASTGDTTPLPVT 1828

Query: 332  SDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA--PSQGIPQGASTTPQAPTHP 389
              S  +    TS P++  S   +  T   P    +SVS    +  +   AS+     T P
Sbjct: 1829 DASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTP 1888

Query: 390  SRVSESTISGAKEETVATLTMTDRVPS------PLSTVVSTATGN 428
              V+++  +   + T   +T    V +      P++++ S +TG+
Sbjct: 1889 LPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGD 1933



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 105/447 (23%), Positives = 165/447 (36%), Gaps = 67/447 (14%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHS-STRHTSVVMLTPNPDGPPSQAA------------ 78
            P P  SL  + +G      VT+P S ST H + +++T        QA             
Sbjct: 3040 PLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVST 3099

Query: 79   -----APMATPTPRAEGH----PPTHTIS-----TIAATVTAPHSESSLSTGPAPAAMAT 124
                  P+ +P+  + GH    P T T S     T +  VT   S  +  T   P    +
Sbjct: 3100 GDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTS 3159

Query: 125  TSSKPEGRP----------RGQAAPTILLTKPPGATSRPT----TAPPRTTT-RRPPRPP 169
            +SS  +  P           G A P ++      +T   T    T+P   +T    P P 
Sbjct: 3160 SSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPV 3219

Query: 170  GSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP----SSTPLGQKRPLGKIFQIYKGNFT 225
              +   +   + P+P    G S +  G   R P    SS   GQ  PL           T
Sbjct: 3220 TDTSSVSTGHATPLPVT--GLSSASTGDTTRLPVTDISSASTGQATPLP--VTNTSSVST 3275

Query: 226  GSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTT----SLGPAKDKPGLR 281
            G   P P T +P +   G+ ++P P T  ++    + +  P T+    S G     P   
Sbjct: 3276 GDTMPLPVT-SPSSASTGH-ATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTD 3333

Query: 282  RAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPG 341
             ++   G T      +P  ++AS    +P    +PS     GD    P    S  +    
Sbjct: 3334 TSSASTGDTTPLPVTSP--SSASTGHTTPLHVTIPSS-ASTGDTSTLPVTGASSASTGHA 3390

Query: 342  TSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAK 401
            T  P++ +S V T    P P    TS+S+ S G      TTP   T  S  S    +   
Sbjct: 3391 TPLPVTDTSSVSTGHATPLPV---TSLSSVSTG-----DTTPLPVTDASSASTGQATPLP 3442

Query: 402  EETVATLTMTDRVPSPLSTVVSTATGN 428
              ++++++  D  P  ++   S +TG+
Sbjct: 3443 VTSLSSVSTGDTTPLLVTDASSVSTGH 3469



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 106/434 (24%), Positives = 166/434 (38%), Gaps = 63/434 (14%)

Query: 49   TMVTAPHSS-TRHTSVVMLTPNPDG-----PPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            T  + P SS +R TS    TP+  G     P        +  T R   +P   + +T + 
Sbjct: 785  TQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQST 844

Query: 103  T----VTAPHSESSLSTGPAPAAMATT------SSKPEGRPRGQAAPTILLTKPPGATSR 152
            T     +A H    +STG A + +  T       +   GRP GQ++PT      P A+ +
Sbjct: 845  TELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPT-----SPSASPQ 899

Query: 153  PTTAPPRTT-TRRPPRPPGSSR----KGAGNSSRPVPPAPGG-------------HSRSK 194
             T A  R   T+R     GS        A ++   VPP P               H+ S 
Sbjct: 900  ETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSP 959

Query: 195  EGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVA 254
             G  G+  ++  +    PL   +     +   +    P  +T  + +    ++P P T  
Sbjct: 960  SGS-GKTFTTALISNATPLPVTY----ASSASTGHTTPLHVTDASSVSTGHATPLPVTSP 1014

Query: 255  ATTVPSNTSWAPTT-TSLGPAKDKPGLRRAAQGGGSTFTSQGGTP----DATAASGAPVS 309
            ++    +T+  P T TS         L   +    ST  S   TP    D ++AS   V+
Sbjct: 1015 SSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDS---TPLPVTDTSSASTGHVT 1071

Query: 310  PQAAPVPS-QRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSV 368
            P   PV S      GD    P    S  +    TS P++ +S V T  T P P    +S 
Sbjct: 1072 P--LPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSA 1129

Query: 369  S---APSQGIPQGAS-----TTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLST 420
            S   A S  +   +S     TTP   T  S  S    +     ++++++  D  P P+++
Sbjct: 1130 STGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTS 1189

Query: 421  VVSTATGNFLNRLV 434
              S +TG+    LV
Sbjct: 1190 PSSASTGHATPLLV 1203



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 92/401 (22%), Positives = 136/401 (33%), Gaps = 43/401 (10%)

Query: 33  SPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHP 92
           SP+ES  V   G       T    +TR  S +  T     P S            A GH 
Sbjct: 627 SPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFT---------ASGHS 677

Query: 93  PTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTI--LLTKPPGAT 150
           P+  +   A T++A  + +   TG      A T++        QAAP+       P G T
Sbjct: 678 PSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTAL-------QAAPSSHDATLGPSGGT 730

Query: 151 SRPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQK 210
           S   T            P G   +    S+   P      + + + +       T   + 
Sbjct: 731 SLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEP 790

Query: 211 RPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS-WAPTTT 269
              G      +    G+  P  S  +  TP      S   +T   ++ PS  S    +TT
Sbjct: 791 ASSGS-----RTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTT 845

Query: 270 SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAAS--GAPVSPQAAPVPSQRPHHGDPQD 327
            L  A    G    + G  S+       P  + AS  G P    +   PS       PQ+
Sbjct: 846 ELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPS-----ASPQE 900

Query: 328 GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPT 387
             + S    T    TSR   T S + + AT        T  S  S G+     T+PQ  T
Sbjct: 901 TAAISRMAQTQRTRTSRGSDTIS-LASQATDTFSTVPPTPPSITSTGL-----TSPQTET 954

Query: 388 HPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
           H    S S       +T  T  +++  P P++   S +TG+
Sbjct: 955 HTLSPSGS------GKTFTTALISNATPLPVTYASSASTGH 989



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 90/359 (25%), Positives = 119/359 (33%), Gaps = 45/359 (12%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            S    G     P +ST   S    TP P   PS A+   ATP P       T + ST   
Sbjct: 3863 SSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS----TSSASTGDT 3918

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
            T     + SSLSTG A     T+   P    RG  +           T   T A   +T 
Sbjct: 3919 TPLPVTNASSLSTGHATPLHVTS---PSSASRGDTS-----------TLPVTDASSASTG 3964

Query: 163  RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKG 222
               P P  S    +   + P+P                + SS   GQ  PL         
Sbjct: 3965 HATPLPLTSLSSVSTGDTTPLPVT--------------DTSSASTGQATPLP--VTSLSS 4008

Query: 223  NFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRR 282
              TG   P P T+ P +   G+++S      ++ +    T    T+TS     D   L  
Sbjct: 4009 VSTGDTTPLPVTI-PSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPV 4067

Query: 283  AAQGGGST--FTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPS-------HSD 333
                  ST   T    T  ++A++G         + S    H  P    S        SD
Sbjct: 4068 TDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSD 4127

Query: 334  SWLTV-TPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSR 391
            S L + TPG + P   + G    AT P P    T +S          ST    P  P R
Sbjct: 4128 SPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILPER 4186



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 102/421 (24%), Positives = 137/421 (32%), Gaps = 81/421 (19%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            S    G     P +ST   S   +TP     PS A+   ATP P         T  T+  
Sbjct: 1271 SSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLP-VTSLSSASTGDTMPL 1329

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
             VT+P S S+  T P P   A++ S       G   P  +           T A   +T 
Sbjct: 1330 PVTSPSSASTGDTTPLPVTDASSVST------GHTTPLHV-----------TDASSASTG 1372

Query: 163  RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKG 222
            +  P P  S    +   + P+P                +PSS   G   PL  +      
Sbjct: 1373 QATPLPVTSLSSVSTGDTTPLPVT--------------SPSSASTGHATPL--LVTDTSS 1416

Query: 223  NFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRR 282
              TG   P P T          S S    T    T+PS  S   TT    P  D      
Sbjct: 1417 ASTGHATPLPVTDAS-------SVSTDHATSLPVTIPSAASTGHTTPL--PVTDTSS--- 1464

Query: 283  AAQGGGS----TFTSQGGTPDAT--------AASGAPVSP------------QAAPVPS- 317
            A+ G  +    T TS   T D T        +AS   V+P             A P+P  
Sbjct: 1465 ASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVT 1524

Query: 318  --QRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVS------ 369
                   GD    P  S S  +    T  P++ +S V T  T P P    +S S      
Sbjct: 1525 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTP 1584

Query: 370  --APSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATG 427
                         TTP   T PS  S    +       ++ +  D  P P++   S +TG
Sbjct: 1585 LPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTG 1644

Query: 428  N 428
            +
Sbjct: 1645 H 1645



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 106/443 (23%), Positives = 161/443 (36%), Gaps = 64/443 (14%)

Query: 33   SPRESLQVLPS------GTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP 86
            +P  +LQ  PS      G   GT ++   + T   SVV     P+G  + A+A  +  T 
Sbjct: 708  APTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTA 767

Query: 87   RAEGHPPTHTISTIAA---TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILL 143
             A  H  TH   +  A   T T+  + S   T  A  A  ++S      P G        
Sbjct: 768  AAMTH--THQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEG----- 820

Query: 144  TKPPGATSRPTTAPPR---TTTRRPPRPPGSSRKGA-----GNSSRPVPPA--PGGHSRS 193
                G T+R ++ P R   TT         S+  GA     G +S  VP    P     S
Sbjct: 821  ISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEAS 880

Query: 194  KEGQ-RGRNPSSTPLGQKRPLGKIFQIY--------KGNFTGSVEPEP----STLTPRTP 240
              G+  G++  ++P    +    I ++         +G+ T S+  +     ST+ P  P
Sbjct: 881  TAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPP 940

Query: 241  LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDA 300
                +    PQT   T  PS +    TT  +  A   P    ++   G T        DA
Sbjct: 941  SITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLH--VTDA 998

Query: 301  TAASGAPVSPQAAPVPSQ-RPHHGDP---QDGPSHSDSWLTVTPGTS-----------RP 345
            ++ S    +P     PS     H  P    D  S S   +T  P TS            P
Sbjct: 999  SSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLP 1058

Query: 346  LSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETV 405
            ++ +S   T    P P    TS+S+ S G      TTP   T  S  S    +       
Sbjct: 1059 VTDTSSASTGHVTPLPV---TSLSSASTG-----DTTPLPVTDTSSASTGHATSLPVTDT 1110

Query: 406  ATLTMTDRVPSPLSTVVSTATGN 428
            ++++     P P++   S +TG+
Sbjct: 1111 SSVSTGHTTPLPVTDTSSASTGH 1133



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 101/431 (23%), Positives = 148/431 (34%), Gaps = 53/431 (12%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            S  P G   + P +     S    TP P    S  +   ATP P  +    T ++ST  A
Sbjct: 1959 SSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTD----TSSVSTGQA 2014

Query: 103  TVTAPHSESSLSTGPA-PAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
            T     S SS STG   P  +  TSS   G+       ++        T  P T+P   +
Sbjct: 2015 TPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSAS 2074

Query: 162  TRR--PPRPPGSSRKGAGNS-SRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQ 218
            T    P     +S    G++ S  V  A    +         + SS   G   PL     
Sbjct: 2075 TGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSP 2134

Query: 219  IYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTS---LGPAK 275
                  TG   P P T T        +S P   T +A+T  + TS   T TS    G A 
Sbjct: 2135 --SSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHA-TSLPVTDTSSASTGHAT 2191

Query: 276  DKPGLRRAAQGGGSTFTSQGGTPDATAASGAPV-----------SPQAAPVPS---QRPH 321
              P    ++   G   T    T  ++A++G  +           + QA P+P        
Sbjct: 2192 PLPVTDTSSASTGQA-TPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSAS 2250

Query: 322  HGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA----------- 370
             GD    P    S ++    TS P+++ S V T  T P P    +S S            
Sbjct: 2251 TGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDA 2310

Query: 371  -------------PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSP 417
                          S        TTP   T PS  S    +       ++++  D  P P
Sbjct: 2311 SSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLP 2370

Query: 418  LSTVVSTATGN 428
            +++  S ++G+
Sbjct: 2371 VTSSSSASSGH 2381



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 98/409 (23%), Positives = 143/409 (34%), Gaps = 41/409 (10%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            PS    G     P +ST   S    TP P    S A+    TP P  +    + T  T  
Sbjct: 3286 PSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSAS-TGDTTP 3344

Query: 102  ATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTT 161
              VT+P S S+  T P    + +++S  +         T+ +T    A++   T  P T 
Sbjct: 3345 LPVTSPSSASTGHTTPLHVTIPSSASTGD-------TSTLPVTGASSASTGHATPLPVTD 3397

Query: 162  T------RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNP----SSTPLGQKR 211
            T         P P  S    +   + P+P      S +  GQ    P    SS   G   
Sbjct: 3398 TSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDA--SSASTGQATPLPVTSLSSVSTGDTT 3455

Query: 212  PLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL 271
            PL  +        TG   P P T T        +  P   T +A+T  +      + +S+
Sbjct: 3456 PL--LVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSV 3513

Query: 272  GPAKDKPGLRRAAQGGGS--------TFTSQGGTPDAT----AASGAPVSPQAAPVPSQR 319
                  P L   A    +        T TS   T D T      + +  + QA P+P   
Sbjct: 3514 STGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTI 3573

Query: 320  PHHGDP-QDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQG 378
            P         P    S  +V+ G   PL  +S   +A+TG       TS S+ S G    
Sbjct: 3574 PSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTS-PSSASTGHVTPLPVTSTSSASTG---- 3628

Query: 379  ASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATG 427
               TP   T  S VS    +       ++ +  D  P P++   S +TG
Sbjct: 3629 -HATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTG 3676



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 116/477 (24%), Positives = 166/477 (34%), Gaps = 93/477 (19%)

Query: 41   LPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTP-------------- 86
            +PS    G   T P +     S    TP P    S  +   ATP P              
Sbjct: 3365 IPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTP 3424

Query: 87   ----------RAEGHP-PTHTISTIAATVTAP---HSESSLSTGPA-PAAMATTSSKPEG 131
                        +  P P  ++S+++   T P      SS+STG A P  +  TSS   G
Sbjct: 3425 LPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTG 3484

Query: 132  ------------RPRGQAAP---TILLTKPPGATS--RPTTAPPRTTTRRPPRP-PGSSR 173
                           GQA P   T L +   G T+    T A   +T    P P   +S 
Sbjct: 3485 DTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSS 3544

Query: 174  KGAGNSSR-PVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPL----------GKIFQIY-- 220
               G+++R PV       +          PSS+  G   PL          G +  ++  
Sbjct: 3545 ASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVT 3604

Query: 221  --KGNFTGSVEPEPSTLTP------RTPLWGYSSS--------PQPQTVAATTVPSNTSW 264
                  TG V P P T T        TPL    +S        P P T A++    +T+ 
Sbjct: 3605 SPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTP 3664

Query: 265  APTT----TSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRP 320
             P T     S G A   P    ++   G   T+     DA++AS    +P    +PS   
Sbjct: 3665 LPVTDTSSASTGQATPLPVTSLSSVSTGD--TTPLPVTDASSASTGHATPLPVTIPSS-V 3721

Query: 321  HHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGAS 380
              GD    P  S S  +    T  P++  S   T  T P P   DTS ++     P   +
Sbjct: 3722 STGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVT-DTSSASTRHATPLPVT 3780

Query: 381  TTPQAPT-HPSRVSESTISGAKEETVATLTMT--------DRVPSPLSTVVSTATGN 428
             T  A T   +R+  + +S A       L +T        D  P P++   S +TG+
Sbjct: 3781 DTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGH 3837



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 99/401 (24%), Positives = 151/401 (37%), Gaps = 41/401 (10%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
            S    G   + P + T   S    T  P    S A+   ATP P  +    T + ST  A
Sbjct: 2151 SSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTD----TSSASTGQA 2206

Query: 103  TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT-- 160
            T     S SS STG A   + T +S       GQA P + +T    A++  TT  P T  
Sbjct: 2207 TPLPVTSPSSASTGHAIPLLVTDTSSAS---TGQATP-LPVTSLSSASTGDTTPLPVTDA 2262

Query: 161  ----TTRRPPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQRGRNPSSTPLGQKR 211
                T      P  S    +   + P+P      A  GH+         + SS   G   
Sbjct: 2263 SSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVT---DASSASTGHAT 2319

Query: 212  PLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSL 271
            PL  +  +   + TG   P P T +P +   G+++ P   T A++    +T+  P T+S 
Sbjct: 2320 PL-PVTSLSSAS-TGDTTPLPVT-SPSSASTGHAT-PLHVTDASSVSTGDTTPLPVTSSS 2375

Query: 272  ----GPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD 327
                G     P    ++   G T T    T  ++A++G         + S     GD   
Sbjct: 2376 SASSGHTTPLPVTDASSASTGDT-TPLPVTDTSSASTGHATHLPVTGLSSAST--GDTTR 2432

Query: 328  GPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPT 387
             P  + S  +    T  P++++S   T  T P P    +SVS           TTP   T
Sbjct: 2433 LPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVST--------GHTTPLLVT 2484

Query: 388  HPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
              S VS    +     + ++ +     P P++   S +TG+
Sbjct: 2485 DASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTGD 2525



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 107/493 (21%), Positives = 182/493 (36%), Gaps = 85/493 (17%)

Query: 32   PSPRESLQVLPSG--TP-PGTMVTAPHSSTRHTSVVMLTPN-----------PDGPPSQA 77
            P P  S     +G  TP PGT  ++   ST HT+ +++T             P   PS A
Sbjct: 2448 PLPVTSTSSASTGDTTPLPGTDTSSV--STGHTTPLLVTDASSVSTGDTTRLPVTSPSSA 2505

Query: 78   AAPMATP-----TPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKP--- 129
            +    TP     TP A     T    T A++++  H+ S   T P+ A+    +S P   
Sbjct: 2506 STGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTD 2565

Query: 130  -EGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT------RRPPRPPGSSRKGAGNSSRP 182
                  G A P + +T    A++  TT  P T T      +  P P   +   +   + P
Sbjct: 2566 TSAASTGHATP-LPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTP 2624

Query: 183  VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLW 242
            +P          +        +TPL    P+     +  G+ T      PS+ +      
Sbjct: 2625 LPVT--------DTSSASTGHATPL----PVTNTSSVSTGHATPLHVTSPSSASTG---- 2668

Query: 243  GYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATA 302
               ++P P T A++    + +  P T +                  S FT    +   T 
Sbjct: 2669 --HTTPLPVTDASSVSTGHATSLPVTDA-----------------SSVFTGHATSLPVTI 2709

Query: 303  ASGAPVSPQAAPVP---SQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGP 359
             S A  S    P+P   +     G     P    S ++    T  P++ +S V T    P
Sbjct: 2710 PSSAS-SGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP 2768

Query: 360  TPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLS 419
             P    TS+S+ S G      TTP   T  S  S    +     ++++++  D  P P++
Sbjct: 2769 LPL---TSLSSVSTG-----DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVT 2820

Query: 420  TVVSTATGNFLNRLVPAGTWKPGTAGNISHVAEGDKPQ----HRATICLSKMDIAWVILA 475
               S +TG+  +  +P       + G+ + + + D       H   + ++    A +  A
Sbjct: 2821 DTSSASTGHATS--LPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHA 2878

Query: 476  ISVPISSCSVLLT 488
             S+P++  S + T
Sbjct: 2879 TSLPVTDTSSIST 2891



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 109/450 (24%), Positives = 170/450 (37%), Gaps = 58/450 (12%)

Query: 45   TPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAA-PMATPTPRAEGH----PPTH--TI 97
            T P  +  A   ST H + + +T         A + P+  P+  + GH    P T   ++
Sbjct: 2670 TTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSV 2729

Query: 98   STIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAP 157
            ST  AT       SS+STG A     T +S       G A P + LT     ++  TT  
Sbjct: 2730 STGHATSLPVTDASSVSTGHATPLPVTDASSVS---TGHATP-LPLTSLSSVSTGDTTPL 2785

Query: 158  PRTTT------RRPPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQRGRNPSSTP 206
            P T T      +  P P  S    +   + P+P      A  GH+ S       + SS  
Sbjct: 2786 PVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVT---DTSSAS 2842

Query: 207  LGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATT---VPSNTS 263
             G   PL           TG     P T T    +   +S P   T + +T    P + +
Sbjct: 2843 TGHATPLPDTDT--SSASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVT 2900

Query: 264  WAPTTTSLGPAKDKPGLRRAAQGGG----------STFTSQGGTPDATAASGAPVSPQAA 313
             +P++ S G A   P    ++   G          S+ ++   TP     + +  +  A 
Sbjct: 2901 -SPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHAT 2959

Query: 314  PVPS---QRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSA 370
            P+P         GD    P  S S  +    T  P++ +S   +A+TG   A   TS S+
Sbjct: 2960 PLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTS---SASTGQATALPVTSTSS 3016

Query: 371  PSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFL 430
             S G      TTP   T  S  S    +     ++++++  D  P P+++  S +TG+  
Sbjct: 3017 ASTG-----DTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 3071

Query: 431  NRLV------PAGTWKPGTAGNISHVAEGD 454
              LV        G   P    ++S V+ GD
Sbjct: 3072 PLLVTDASSASTGQATPLPVTSLSSVSTGD 3101



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 104/423 (24%), Positives = 148/423 (34%), Gaps = 53/423 (12%)

Query: 43   SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAE------GH----- 91
            S    G   + P + T   S    TP PD   S A+   AT  P  +      GH     
Sbjct: 2823 SSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLP 2882

Query: 92   -PPTHTISTIAATVTAPHSESSLSTGPA-PAAMATTSSKPEGRPRGQAAPTILLTKPPGA 149
               T +IST  AT     S SS STG A P  +  TSS   G      A  + +T P  A
Sbjct: 2883 VTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGH-----ANPLHVTSPSSA 2937

Query: 150  TSRPTTAPPRTTT------RRPPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQR 198
            ++   T  P T T         P P  S    +   + P+P      A  GH+       
Sbjct: 2938 STGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLP--- 2994

Query: 199  GRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTV 258
              + SS   GQ   L           TG   P P T T         ++P P T  ++  
Sbjct: 2995 VTDTSSASTGQATALP--VTSTSSASTGDTTPLPVTDTSSASTG--QATPLPVTSLSSVS 3050

Query: 259  PSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQG-GTPDATAASGAPVSPQAAPVPS 317
              +T+  P T+   P+    G         ++  S G  TP    +  +  +    P+P 
Sbjct: 3051 TGDTTPLPVTS---PSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 3107

Query: 318  QRPHH---GDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG 374
              P     G     P    S  +    TS P++ +S  +T  T   P   DTS S+    
Sbjct: 3108 TSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVT-DTSSSSTGDT 3166

Query: 375  IP------QGAST---TPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTA 425
             P         ST   TP   T  S  S    +     + ++ +  D  P P++   S +
Sbjct: 3167 TPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVS 3226

Query: 426  TGN 428
            TG+
Sbjct: 3227 TGH 3229



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 107/425 (25%), Positives = 155/425 (36%), Gaps = 59/425 (13%)

Query: 42   PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIA 101
            PS    G     P + T   S   +TP P    S A+   +TP P  +    T + ST  
Sbjct: 1014 PSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTD----TSSASTGH 1069

Query: 102  ATVTAPHSESSLSTGPA-PAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRT 160
             T     S SS STG   P  +  TSS   G      A ++ +T     ++  TT  P T
Sbjct: 1070 VTPLPVTSLSSASTGDTTPLPVTDTSSASTGH-----ATSLPVTDTSSVSTGHTTPLPVT 1124

Query: 161  TTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLG--KIFQ 218
             T        SS      +S PV       +         + SS   GQ  PL    +  
Sbjct: 1125 DT--------SSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSS 1176

Query: 219  IYKGNFTGSVEPEPSTLTP--RTPLWGYSSS--------PQPQTVAATTVPSNTSWAPTT 268
            +  G+ T      PS+ +    TPL    +S        P P T A++    + +  P T
Sbjct: 1177 VSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVT 1236

Query: 269  ----TSLGPAKDKPGLRRAAQGGGS------TFTSQGGTPDAT--------AASGAPVSP 310
                 S G     P    ++   G       T TS   T D T        +AS   V+P
Sbjct: 1237 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1296

Query: 311  QAAPVPSQRPH-HGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVS 369
                 PS     H  P    S S +    + G + PL  +S   +A+TG T     T  S
Sbjct: 1297 LHVTSPSSASTGHATPLPVTSLSSA----STGDTMPLPVTSPS-SASTGDTTPLPVTDAS 1351

Query: 370  APSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNF 429
            + S G      TTP   T  S  S    +     ++++++  D  P P+++  S +TG+ 
Sbjct: 1352 SVSTG-----HTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA 1406

Query: 430  LNRLV 434
               LV
Sbjct: 1407 TPLLV 1411



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 95/427 (22%), Positives = 151/427 (35%), Gaps = 44/427 (10%)

Query: 43  SGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAA 102
           +GT    ++++P  S   T ++    +P   P      +   T +     P+   STI +
Sbjct: 571 TGTTGEALLSSPSYSV--TQMIKTATSPSSSPM-----LDRHTSQQITTAPSTNHSTIHS 623

Query: 103 TVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTT 162
           T T+P    ++S      A  TT      R       T  +T P  + +    +P     
Sbjct: 624 TSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIV- 682

Query: 163 RRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSS--TPLGQKRPLGKIFQIY 220
                P  +    A  +  P P   G  +++        PSS    LG   P G      
Sbjct: 683 -----PQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLG---PSGGTSLSK 734

Query: 221 KGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGL 280
            G  T +     +   P       S+S  P T AA T   +T  A +T + G  +     
Sbjct: 735 TGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMT---HTHQAESTEASGQTQTS--- 788

Query: 281 RRAAQGGGSTFTSQGGTPDATAASG-APVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVT 339
              A  G  T ++   TP ++ ASG  P   +      +           SH+    T  
Sbjct: 789 -EPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTEL 847

Query: 340 PGTSR-----PLST--SSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRV 392
              S      P+ST  +S +      PT +   T+     Q  P   S +PQ     SR+
Sbjct: 848 LSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRM 907

Query: 393 SES----------TISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPG 442
           +++          TIS A + T    T+    PS  ST + T+     + L P+G+ K  
Sbjct: 908 AQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGL-TSPQTETHTLSPSGSGKTF 966

Query: 443 TAGNISH 449
           T   IS+
Sbjct: 967 TTALISN 973



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 103/422 (24%), Positives = 159/422 (37%), Gaps = 56/422 (13%)

Query: 45   TPPG---TMVTAPHSSTRHTSVVMLTPNPDGPP-SQAAAPMATPTP------RAEGHP-P 93
            TPP    T +T+P + T HT    L+P+  G   + A    ATP P       + GH  P
Sbjct: 938  TPPSITSTGLTSPQTET-HT----LSPSGSGKTFTTALISNATPLPVTYASSASTGHTTP 992

Query: 94   TH-----TISTIAATVTAPHSESSLSTG-PAPAAMATTSSKPEGRPRGQAAPTILLTKPP 147
             H     ++ST  AT     S SS+STG   P  +  TSS+  G        +       
Sbjct: 993  LHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTG 1052

Query: 148  GATSRPTTAPPRTTTRR-PPRPPGSSRKGAGNSSRPVP-----PAPGGHSRSKEGQRGRN 201
             +T  P T     +T    P P  S    +   + P+P      A  GH+ S       +
Sbjct: 1053 DSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSS 1112

Query: 202  PSS---TPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTP--RTPLWGYSSS--------P 248
             S+   TPL    P+        G+ T     + S+++    TPL    +S        P
Sbjct: 1113 VSTGHTTPL----PVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATP 1168

Query: 249  QPQTVAATTVPSNTSWAPTTT--SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGA 306
             P T  ++    +T+  P T+  S       P L        +   +     DA++ S  
Sbjct: 1169 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1228

Query: 307  PVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDT 366
              +     +PS     G     P    S  +    TS  ++ +S V T  T P P    T
Sbjct: 1229 HATSLPVTIPSAAST-GHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPV---T 1284

Query: 367  SVSAPSQGIPQGASTTPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTAT 426
            S S+ S G       TP   T PS  S    +     ++++ +  D +P P+++  S +T
Sbjct: 1285 STSSASTG-----HVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAST 1339

Query: 427  GN 428
            G+
Sbjct: 1340 GD 1341



 Score = 36.2 bits (82), Expect = 0.084
 Identities = 88/430 (20%), Positives = 150/430 (34%), Gaps = 70/430 (16%)

Query: 34  PRESLQVLPSGTPPGTMVTAPHSST-----RHTSVVMLTPNPDGPPSQAAAPMATPTPRA 88
           P  +   L +G+     VT+  S+T     + T+    T N D   S       +    +
Sbjct: 27  PGTTEDTLITGSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTS 86

Query: 89  EGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPP- 147
           +    T T    +   ++P   + + T P P  M T+            + TI +T    
Sbjct: 87  KAQTDTLTQMMTSTLFSSPSVHNVMETAP-PDEMTTSFPSSVTNTLMMTSKTITMTTSTD 145

Query: 148 ---GATSRPTTA------PPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQR 198
              G T   +TA      P  +         G SR  +  +S     A   +  ++  Q 
Sbjct: 146 STLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSASSQNHWTRSTQT 205

Query: 199 GRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPE--PSTLTPRTPLWGYSSSPQ--PQTVA 254
            R   ++ L  +      F     N TG+V  +  PS  T  + L   +++     + + 
Sbjct: 206 TRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKIT 265

Query: 255 ATTV-------PSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAP 307
            TT        P  TS  P T SL P      +    +G      S+  T D TA S   
Sbjct: 266 VTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSK-- 323

Query: 308 VSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTS 367
            + Q   V + R          S  ++  T+TP T+  + +S           P+ F+ S
Sbjct: 324 -NHQTQSVETTRV---------SQINTLNTLTPVTTSTVLSS-----------PSGFNPS 362

Query: 368 VSAPSQGIPQGASTTPQAPTHPSRVS----------------ESTISGAKEETVATLTMT 411
            +   +  P G +TT    + PS VS                +ST+   +E +++     
Sbjct: 363 GTVSQETFPSGETTT----SSPSSVSNTFLVTSKVFRMPTSRDSTLGNTEETSLSVSGTI 418

Query: 412 DRVPSPLSTV 421
             + S +ST+
Sbjct: 419 SAITSKVSTI 428



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 25/168 (14%)

Query: 41   LPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTI 100
            +PS    G   + P +     S    TP P    S A+    TP P  +    T + ST 
Sbjct: 4021 IPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTD----TSSASTG 4076

Query: 101  AATVTAPHSESSLSTG---PAPAAMATTSSKPEGRPRGQAAPTILLT---------KPPG 148
             AT       SS STG   P P    ++ S     P   ++ T   T         + PG
Sbjct: 4077 HATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPG 4136

Query: 149  ATS---------RPTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAP 187
             T+         R  T+PP TT++       S+     +++ P+P  P
Sbjct: 4137 MTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPIPILP 4184


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 109/475 (22%), Positives = 172/475 (36%), Gaps = 80/475 (16%)

Query: 44   GTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAAT 103
            G+PP   V     S R        P P    ++ A P  +P P A   PP   +++ ++ 
Sbjct: 971  GSPPTLRVHGDTGSPRKPWPERRPPRPAA--TRTAPPTPSPGPSASPGPPGPALTSDSSR 1028

Query: 104  VTAPHSE-SSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKP------------PGAT 150
               PHS  +S +T  AP      +S P   P  +  P ++LT P            P  T
Sbjct: 1029 ELTPHSALTSEATSDAP-----DTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALT 1083

Query: 151  SRPTTAP----PRTTTRRPPRP-------PGSSRKGAGNSSRPVPPAP-----GGHSRSK 194
              P+  P    P+  T  P  P       P S +    +++  +   P       +SRS 
Sbjct: 1084 PEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSP 1143

Query: 195  EGQRGRNPSST--PLGQKRPLGKIFQIYKGNFT----GSVEPEPSTLTPRTPLWGYSSSP 248
            +     +P++T  P     P+  +      +F      +  P P+T+T  T +   +++P
Sbjct: 1144 DPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTP 1203

Query: 249  QP--------------------QTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGG 288
            QP                     T+  TT P +T+  PTTT          +        
Sbjct: 1204 QPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTP 1263

Query: 289  STFTSQGGT----PDATAASGAPVSPQAAPVPSQRPH---HGDPQDGPSHSDS-WLTVTP 340
              FT+   T    P  T        P   P P+  PH     DP   P  + +   T TP
Sbjct: 1264 QPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTP 1323

Query: 341  GTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQG-------IPQGASTTPQAPTHPSRVS 393
              + P  +S+ V T  + PT  +  T +S+P+          PQ   T P   T  S++ 
Sbjct: 1324 HPTTPDPSSTPVITTVSLPT--SLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIP 1381

Query: 394  ESTISGAKEETVATLTMTDRVPSPLSTVVSTATGNFLNRLVPAGTWKPGTAGNIS 448
                S A E +  + + T     PLST       +    L P  T  P +A +++
Sbjct: 1382 TLEPSPALESS-PSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLT 1435



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 74/319 (23%), Positives = 106/319 (33%), Gaps = 40/319 (12%)

Query: 46   PPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHTISTIAATVT 105
            P  T    P ++  H++++   P+P   P        T TP +    PT T      T +
Sbjct: 1197 PDPTTTPQPFTTITHSTMI---PDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHS 1253

Query: 106  APHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAPPRTTTRRP 165
                + + +  P      TT   P   P     P    T  P  T  PT  P  TTT  P
Sbjct: 1254 TMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYP 1313

Query: 166  PRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPL--GQKRPLGKIFQIYKGN 223
               P         ++ P P  P             +PSSTP+      P     ++    
Sbjct: 1314 TTTPDP-------TTTPHPTTP-------------DPSSTPVITTVSLPTSLGTELSSPT 1353

Query: 224  FTGSVEPE-PSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRR 282
               +V+P     LT   P    S+S  P    +  + S+ S + T TS+ P   +     
Sbjct: 1354 LAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPP 1413

Query: 283  AAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTPGT 342
             +Q    T       P  T  S + ++    P+ S   H   P D P      L  TPG 
Sbjct: 1414 RSQSPNLT-----PPPTHTPHSASDLTVSPDPLLSPTAH---PLDHPPLDPLTLGPTPG- 1464

Query: 343  SRPLSTSSGVFTAATGPTP 361
                  S G       PTP
Sbjct: 1465 -----QSPGPHGPCVAPTP 1478



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 109/406 (26%), Positives = 145/406 (35%), Gaps = 88/406 (21%)

Query: 37   SLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTHT 96
            S QV  S T P  + T P+SST    V   + +PD  PS +  P  TP P     P    
Sbjct: 1115 SEQVPESDTTPD-LDTTPYSST----VSEYSRSPD--PSPSPHPTTTPDPTMAPDP---- 1163

Query: 97   ISTIAATVTAPHSESS--LSTGPAPAAMATTSSKPEGRPRGQAAPTI---------LLTK 145
            I+T+  TVT PH  ++   +T P P  +  ++  P+     Q   TI           T 
Sbjct: 1164 ITTLNPTVT-PHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTP 1222

Query: 146  PPGATSRPTTAP----PRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRN 201
             P  T +PTT P    P  TT   P     S      ++ P P      +         +
Sbjct: 1223 QPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPH 1282

Query: 202  PSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGY-SSSPQPQTVAATTVPS 260
            P++TP     P              +  P P T+TP      Y +++P P T    T P 
Sbjct: 1283 PTTTPHPTTTP------------HPTTTPHP-TMTPDPTTTPYPTTTPDPTTTPHPTTPD 1329

Query: 261  NTSWAPTT-----TSLGPAKDKPGLRRAAQ-----------GGGSTFTSQGGTPD----- 299
             +S    T     TSLG     P L    +               T TSQ  T +     
Sbjct: 1330 PSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPAL 1389

Query: 300  -------ATAASGAPVSPQ-AAPVPSQRPHHGDPQDGPSHSDSWLTVTPG-----TSRPL 346
                   +TA S  P+S +   P  SQ P+   P     HS S LTV+P      T+ PL
Sbjct: 1390 ESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPL 1449

Query: 347  STSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHPSRV 392
                 +     GPTP            G   G      APT P RV
Sbjct: 1450 D-HPPLDPLTLGPTP------------GQSPGPHGPCVAPTPPVRV 1482



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 38/141 (26%), Positives = 57/141 (40%), Gaps = 29/141 (20%)

Query: 32   PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH 91
            P+P  S   +P+  P   + ++P  S+  TS+  L+   D  P ++ +P  TP       
Sbjct: 1371 PAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLS-TEDFKPPRSQSPNLTP------- 1422

Query: 92   PPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATS 151
            PPTHT          PHS S L+  P P  + + ++ P   P       + L   PG + 
Sbjct: 1423 PPTHT----------PHSASDLTVSPDP--LLSPTAHPLDHP---PLDPLTLGPTPGQSP 1467

Query: 152  RP------TTAPPRTTTRRPP 166
             P       T P R     PP
Sbjct: 1468 GPHGPCVAPTPPVRVMACEPP 1488



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 13/113 (11%)

Query: 298 PDATAASGAPVSPQAAPVPS----QRPHHGDPQDGPSHSDSWLTVTPGTSRPLSTSSGVF 353
           PD T+ + A ++ +A+  P+    +RP    PQ   SH+ +  T+TP   R  +T +   
Sbjct: 658 PDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTA--TLTPQAPRERTTKTMAM 715

Query: 354 TAATGPTPAAFDTSVSA-------PSQGIPQGASTTPQAPTHPSRVSESTISG 399
               GP     ++++ +       PS  IP+G+  +P+ P     VS +  SG
Sbjct: 716 LTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPAPSPSVSTTGESG 768



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 41/157 (26%), Positives = 59/157 (37%), Gaps = 24/157 (15%)

Query: 27   FAIQEPS--PRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATP 84
            F   +P+  P  +    P+ TP  T  T PH +T     +   P     P+    P  TP
Sbjct: 1266 FTTMQPTTMPHPTTTPHPTTTPHPT--TTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTP 1323

Query: 85   TPRAEGHPPTHTISTI----------AATVTAPHSESSLS---TGPAPAAMATTSSKPEG 131
             P       T  I+T+          ++   AP  + SL    T  APA   +TS  P  
Sbjct: 1324 HPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIP-- 1381

Query: 132  RPRGQAAPTILLTKPPGATSRPTTAPPRTTTR-RPPR 167
                   P+  L   P  +S  T+  P +T   +PPR
Sbjct: 1382 ----TLEPSPALESSPSRSSTATSMDPLSTEDFKPPR 1414



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 57/223 (25%), Positives = 79/223 (35%), Gaps = 31/223 (13%)

Query: 221  KGNFTGSVEPEPSTLTPRTPLWGYSSSPQ----PQTVAATTVPSNTSWAPTTTSLGPAKD 276
            KG  T  V     TL  RT     SSSP     P T +        +W  T +  G A+ 
Sbjct: 895  KGTTTAGVPGH--TLPWRTTRRPGSSSPAIRRLPDTGSKDGYKLPWTW-DTPSGRGLAEG 951

Query: 277  KPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHG--------DPQDG 328
             P   +     G+  T   G+P      G   SP+  P P +RP            P  G
Sbjct: 952  TPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRK-PWPERRPPRPAATRTAPPTPSPG 1010

Query: 329  PSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTH 388
            PS S       PG   P  TS     ++   TP +  TS +          +  P + T+
Sbjct: 1011 PSAS-------PGPPGPALTSD----SSRELTPHSALTSEATSDAPDTSPPTPDPASRTN 1059

Query: 389  PSRVSES---TISGAKEETVATLTMTDRVPSPLSTVVSTATGN 428
            P  +  S    +S      V  LT  +  P+PL T+    T +
Sbjct: 1060 PDLILTSPDFALSTPDSSVVPALT-PEPSPTPLPTLPKELTSD 1101


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 90/344 (26%), Positives = 134/344 (38%), Gaps = 38/344 (11%)

Query: 96  TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTT 155
           T +   +T T   SE S +   +P + ATT S       G +  +      PG+T   TT
Sbjct: 3   TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH--TT 60

Query: 156 APPRTTTRRPPRPPGSSRKGAGNSSRP----VPPAPGGHSRSKEGQRGRNPSSTPLGQKR 211
           A P +TT      PG SR    + S P        P   + S   Q      S+P     
Sbjct: 61  AFPDSTT-----TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDT 115

Query: 212 PL--GKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTT 269
            L  G    +  G  + +    P   +  T L+  S++      A+T V S+T  +P TT
Sbjct: 116 ALSPGSTTALSFGQESTTFHSSPG--STHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTT 172

Query: 270 SLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGP 329
               +   PGL    QG  + F +    P +T  + +P S   APV     +H  P   P
Sbjct: 173 LSPASSTSPGL----QGESTAFQTH---PASTHTTPSPPSTATAPVEESTTYHRSPGSTP 225

Query: 330 SHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAP--T 387
           +      + T G S   ST       A+G TP    +S  + + G+ + +ST+   P  T
Sbjct: 226 TTHFPASSTTSGHSEK-STIFHSSPDASGTTP----SSAHSTTSGVSEESSTSHSQPGST 280

Query: 388 HPSRVSES-TISGAKEETV-------ATLTMTDRVPSPLSTVVS 423
           H +   +S T SG  +E         +T    D  PSP  T  +
Sbjct: 281 HTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAA 324



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 100/410 (24%), Positives = 148/410 (36%), Gaps = 45/410 (10%)

Query: 22  TEALAFAIQEPSPRESLQVLPSGTPPGTMVTA--PHSSTRHTSVVMLTPNPDGPPSQ--A 77
           T   AF     +P  S     S + PG+  T   P S+T        T +   P S   A
Sbjct: 57  THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTA 116

Query: 78  AAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQA 137
            +P +T T  + G   T   S+  +T T    +S+ S+G   A+    SS   G PR   
Sbjct: 117 LSPGST-TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST--GSPRTTL 173

Query: 138 APTILLTKPPGATSRPTTAPPR-TTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEG 196
           +P    +  PG     T       +T   P PP ++       + PV  +   H      
Sbjct: 174 SPAS--STSPGLQGESTAFQTHPASTHTTPSPPSTA-------TAPVEESTTYH------ 218

Query: 197 QRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP-LWGYSSSPQPQTVAA 255
              R+P STP             +  + T S   E ST+   +P   G + S    T + 
Sbjct: 219 ---RSPGSTPTTH----------FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 265

Query: 256 TTVPSNTSWA-PTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAP 314
            +  S+TS + P +T      D       +Q   ++ +SQG T      + +P    AAP
Sbjct: 266 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAP 325

Query: 315 VPSQRPHHGDPQDGPSHSDSWLTVTPGTSRPLST-----SSGVFTAATGPTPAAFDTSVS 369
           V     +H  P   P+   S  + T G S   +T      S   TA  G T  A  +  S
Sbjct: 326 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKS 385

Query: 370 APSQGIPQGASTT--PQAPTHPSRVSESTISGAKEETVATLTMTDRVPSP 417
                 P+   TT  P + T      EST S ++  +  T         P
Sbjct: 386 TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 435



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 55/192 (28%), Positives = 77/192 (40%), Gaps = 23/192 (11%)

Query: 268 TTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQD 327
           TT+L  +   PGL   +    +TF S   +P AT  S A  +       S   H    + 
Sbjct: 3   TTALPGSTTTPGLSEKS----TTFHSSPRSP-ATTLSPASTTSSGVSEESTTSHS---RP 54

Query: 328 GPSHSDSW--LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQA 385
           G +H+ ++   T TPG SR  ST+S     +T  T     T+ S PSQ      S+    
Sbjct: 55  GSTHTTAFPDSTTTPGLSRH-STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 113

Query: 386 PTHPSRVSESTISGAKEETVA--------TLTMTDRVPSP----LSTVVSTATGNFLNRL 433
            T  S  S + +S  +E T          T    D   S      ST V ++TG+    L
Sbjct: 114 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 173

Query: 434 VPAGTWKPGTAG 445
            PA +  PG  G
Sbjct: 174 SPASSTSPGLQG 185



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 63/268 (23%), Positives = 98/268 (36%), Gaps = 44/268 (16%)

Query: 233 STLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGGGSTFT 292
           ST TP       +    P++ A T  P++T+ +  +     +  +PG         ST T
Sbjct: 9   STTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST-T 67

Query: 293 SQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGP-SHSDSWLTVT---PGTSRPLS- 347
           + G +  +T +  +P S     +P+     G  Q+   SHS    T T   PG++  LS 
Sbjct: 68  TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 127

Query: 348 -----------------------TSSGVFTAATGP-----TPAAFDTSVSAPSQGIPQGA 379
                                  TSSG+  A+T       +P    +  S+ S G+ QG 
Sbjct: 128 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL-QGE 186

Query: 380 ST---TPQAPTHPSRVSESTISGAKEETVATLTMTDRVPSPLSTVVSTATGN------FL 430
           ST   T  A TH +    ST +   EE+          P+      ST +G+      F 
Sbjct: 187 STAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH 246

Query: 431 NRLVPAGTWKPGTAGNISHVAEGDKPQH 458
           +    +GT         S V+E     H
Sbjct: 247 SSPDASGTTPSSAHSTTSGVSEESSTSH 274


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 83/376 (22%), Positives = 142/376 (37%), Gaps = 36/376 (9%)

Query: 43  SGTPPGT-------MVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGHPPTH 95
           S +PPG         + +PH+  +   +  L P P+  P+ A +P + P P +   P   
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQ--GMGGLPPGPEKGPTLAPSPHSLP-PASSSAP--- 367

Query: 96  TISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTT 155
                A  +  P+S SS S+  A ++ +++SS     P  QA P+   + PP  +   + 
Sbjct: 368 -----APPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422

Query: 156 APPRTT----------TRRPPRPPGSSRKGAGNSSR--PVPPAPGGHSRSKEGQRGRNPS 203
            PP+ T          ++ PP PP   R  A +++   P PP+ G  S +       +  
Sbjct: 423 QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHH 482

Query: 204 STPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTS 263
                Q++   +  Q  +    G+  P P    P  PL G SS        + ++ S   
Sbjct: 483 HQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH-PLEGGSSHHAHPYAMSPSLGSLRP 541

Query: 264 WAPTTTSLGPAKDKPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHG 323
           + P    L P   +    +A   G    +S   +   +  S     P  +  P   P+  
Sbjct: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601

Query: 324 DPQDGPSHSDSWLTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTP 383
            P    + S + L+    T   +++S   +  A+ P P  +     APS G  + A+   
Sbjct: 602 PPVPTVTTSSATLSTVIAT---VASSPAGYKTASPPGPPPY--GKRAPSPGAYKTATPPG 656

Query: 384 QAPTHPSRVSESTISG 399
             P  P      T  G
Sbjct: 657 YKPGSPPSFRTGTPPG 672



 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 94/407 (23%), Positives = 140/407 (34%), Gaps = 82/407 (20%)

Query: 73  PPSQAAAPMATPTPRAEGHPPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGR 132
           PP     P   P+P +    P  + S  A  +  P+S SS S+  A ++ +++SS     
Sbjct: 343 PPGPEKGPTLAPSPHSL---PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF 399

Query: 133 PRGQAAPTILLTKPPGATSRPTTAPPRTT----------TRRPPRPPGSSRKGAGNSSRP 182
           P  QA P+   + PP  +   +  PP+ T          ++ PP PP   R  A +++ P
Sbjct: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP 459

Query: 183 --VPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTP 240
              PP+ G  S +       +       Q++   +  Q  +    G+  P P    P  P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH-P 518

Query: 241 LWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKDKPGLRRAAQGG--------GSTFT 292
           L G SS        + ++ S   + P    L P   +    +A   G         S+ T
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST 578

Query: 293 SQGGTPD---------------------------------ATAAS-----------GAPV 308
           SQG  P                                  AT AS           G P 
Sbjct: 579 SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638

Query: 309 SPQAAPVPSQRPHHGDPQDGPSHSDSWLTVTP----GTSRPLSTSS---GVFTAATGPTP 361
             + AP P        P   P    S+ T TP    GTS P    +   G  T   GP P
Sbjct: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP 698

Query: 362 AAFDTSV-------SAPSQGIPQGASTTPQAPTHPSRVSESTISGAK 401
            A  + +       +AP+ G P  A+   Q P       ES +  A+
Sbjct: 699 PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 86/353 (24%), Positives = 120/353 (33%), Gaps = 50/353 (14%)

Query: 42  PSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPR----AEGHPPTHTI 97
           PS  PP +    P +S          P+P   P+   APM  PT R      G PP H  
Sbjct: 167 PSPQPPDSTPRQPEAS--------FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQ 218

Query: 98  STIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTKPPGATSRPTTAP 157
                T       S    GP     A++   P G  +     T +     GA+  P T P
Sbjct: 219 LYPGGTGGV---LSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275

Query: 158 PRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRGRNPSSTPLGQKRPLGKIF 217
           P T              G GN     PPA   H           P+  P    RPL    
Sbjct: 276 PTTPV------------GGGNLPSAPPPANFPHV---------TPNLPPPPALRPLNNAS 314

Query: 218 QIYKGNFTGSVEPEPSTL-TPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTTSLGPAKD 276
               G      +P P  L +P     G    P       T  PS  S  P ++S  PA  
Sbjct: 315 ASPPGL---GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS-APA-- 368

Query: 277 KPGLRRAAQGGGSTFTSQGGTPDATAASGAPVSPQAAPVPSQRPHHGDPQDGPSHSDSWL 336
            P +R       S+  +   +  ++++S +P  P +  +PS  PH   P    S S+   
Sbjct: 369 -PPMRFPYSSSSSSSAAASSSSSSSSSSASPF-PASQALPSY-PHSFPPPTSLSVSNQ-- 423

Query: 337 TVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTPQAPTHP 389
              P  ++P   S  V++    P P       ++ +   P   ST  Q+  HP
Sbjct: 424 --PPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 79/317 (24%), Positives = 108/317 (34%), Gaps = 51/317 (16%)

Query: 109 SESSLSTGPA-----PAAMATTSSKPEGRPRGQAA-----PTILLT------KPPGATSR 152
           S S LS GPA     P     +   P+  PR   A     P++  T      +PP  TSR
Sbjct: 147 SSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPP--TSR 204

Query: 153 PTTAPPRTTTRRPPRPPGSSRKGAGNSSRPVPPAPGGHSRSKEGQRG---RNPSSTPLGQ 209
              APP      P   PG +  G   S  P+ P  GG + S  G  G     P +TP+  
Sbjct: 205 MFQAPPGAPPPHPQLYPGGT--GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262

Query: 210 KRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPLWGYSSSPQPQTVAATTVPSNTSWAPTTT 269
                          +      P T  P TP+ G +    P       V  N    P   
Sbjct: 263 S--------------SSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR 308

Query: 270 SLGPAK-DKPGLRRAAQGGGSTFTSQGGTPDA--TAASGAPVSPQAAPVPSQRPHHGDPQ 326
            L  A    PGL      G         +P A      G P  P+  P  +  PH   P 
Sbjct: 309 PLNNASASPPGL------GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362

Query: 327 DGPSHSDSW---LTVTPGTSRPLSTSSGVFTAATGPTPAAFDTSVSAPSQGIPQGASTTP 383
              + +       + +  +S   S+SS   +++  P PA+        S   P   S + 
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422

Query: 384 QAP--THPSRVSESTIS 398
           Q P  T PS  S++  S
Sbjct: 423 QPPKYTQPSLPSQAVWS 439



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 67/242 (27%), Positives = 95/242 (39%), Gaps = 40/242 (16%)

Query: 32  PSPRESLQVLPSGTPPGTMVTAPHSSTRHTSVVMLTPNPDGPPSQAAAPMATPTPRAEGH 91
           P P   +    +G P G  V++  +S+  TS       P   PS +  P   P P     
Sbjct: 550 PPPHSQVSYSQAG-PNGPPVSSSSNSSSSTSQGSY---PCSHPSPSQGPQGAPYP----F 601

Query: 92  PPTHTISTIAATVTAPHSESSLSTGPAPAAMATTSSKPEGRPRGQAAPTILLTK---PPG 148
           PP  T++T +AT++     + ++T  +  A   T+S P   P G+ AP+    K   PPG
Sbjct: 602 PPVPTVTTSSATLS-----TVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPG 656

Query: 149 -----ATSRPTTAPPRTTTRRPPRPPGSSRKGAGN-SSRPVPPAPGGHSRSKEGQRGRNP 202
                  S  T  PP      PP  PG+ + G+      P+PPA      S         
Sbjct: 657 YKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPA 716

Query: 203 SSTPLGQKRPLGKIFQIYKGNFTGSVEPEPSTLTPRTPL-WGYSSSPQPQTVAATTVPSN 261
           S  PL          QI +       EP     TP +P+    S SP P+ V    VPS+
Sbjct: 717 SGPPLSAT-------QIKQ-------EPAEEYETPESPVPPARSPSPPPKVV---DVPSH 759

Query: 262 TS 263
            S
Sbjct: 760 AS 761


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,640,768
Number of Sequences: 37866
Number of extensions: 1956225
Number of successful extensions: 22694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 255
Number of HSP's successfully gapped in prelim test: 1741
Number of HSP's that attempted gapping in prelim test: 11253
Number of HSP's gapped (non-prelim): 7160
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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