Guide to the Human Genome
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Search of human proteins with 4508045

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo
sapiens]
         (745 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo sap...  1523   0.0  
gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo sa...   211   2e-54
gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]              160   4e-39
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]       92   1e-18
gi|134268640 tectorin alpha precursor [Homo sapiens]                   76   1e-13
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]      67   6e-11
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]      67   6e-11
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...    67   6e-11
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...    67   6e-11
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...    67   6e-11
gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]            65   2e-10
gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2 [...    57   6e-08
gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1 [...    57   6e-08
gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4 [...    57   6e-08
gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3 [...    57   6e-08
gi|160358850 zona pellucida glycoprotein 3 isoform 1 precursor [...    54   7e-07
gi|38327649 zona pellucida glycoprotein 3 isoform 2 [Homo sapiens]     53   9e-07
gi|56550049 uromodulin precursor [Homo sapiens]                        52   3e-06
gi|59850812 uromodulin precursor [Homo sapiens]                        52   3e-06
gi|28372569 zona pellucida-like domain containing 1 [Homo sapiens]     45   2e-04
gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens]      42   0.002
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]      42   0.002
gi|56682966 transforming growth factor, beta receptor III [Homo ...    38   0.030
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 32   2.8  
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         31   3.7  
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ...    31   4.8  
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [...    31   4.8  
gi|33695155 hepsin [Homo sapiens]                                      30   8.1  
gi|4504481 hepsin [Homo sapiens]                                       30   8.1  
gi|31543535 R3H domain containing 1 [Homo sapiens]                     30   8.1  

>gi|4508045 zona pellucida glycoprotein 2 preproprotein [Homo
           sapiens]
          Length = 745

 Score = 1523 bits (3942), Expect = 0.0
 Identities = 745/745 (100%), Positives = 745/745 (100%)

Query: 1   MACRQRGGSWSPSGWFNAGWSTYRSISLFFALVTSGNSIDVSQLVNPAFPGTVTCDEREI 60
           MACRQRGGSWSPSGWFNAGWSTYRSISLFFALVTSGNSIDVSQLVNPAFPGTVTCDEREI
Sbjct: 1   MACRQRGGSWSPSGWFNAGWSTYRSISLFFALVTSGNSIDVSQLVNPAFPGTVTCDEREI 60

Query: 61  TVEFPSSPGTKKWHASVVDPLGLDMPNCTYILDPEKLTLRATYDNCTRRVHGGHQMTIRV 120
           TVEFPSSPGTKKWHASVVDPLGLDMPNCTYILDPEKLTLRATYDNCTRRVHGGHQMTIRV
Sbjct: 61  TVEFPSSPGTKKWHASVVDPLGLDMPNCTYILDPEKLTLRATYDNCTRRVHGGHQMTIRV 120

Query: 121 MNNSAALRHGAVMYQFFCPAMQVEETQGLSASTICQKDFMSFSLPRVFSGLADDSKGTKV 180
           MNNSAALRHGAVMYQFFCPAMQVEETQGLSASTICQKDFMSFSLPRVFSGLADDSKGTKV
Sbjct: 121 MNNSAALRHGAVMYQFFCPAMQVEETQGLSASTICQKDFMSFSLPRVFSGLADDSKGTKV 180

Query: 181 QMGWSIEVGDGARAKTLTLPEAMKEGFSLLIDNHRMTFHVPFNATGVTHYVQGNSHLYMV 240
           QMGWSIEVGDGARAKTLTLPEAMKEGFSLLIDNHRMTFHVPFNATGVTHYVQGNSHLYMV
Sbjct: 181 QMGWSIEVGDGARAKTLTLPEAMKEGFSLLIDNHRMTFHVPFNATGVTHYVQGNSHLYMV 240

Query: 241 SLKLTFISPGQKVIFSSQAICAPDPVTCNATHMTLTIPEFPGKLKSVSFENQNIDVSQLH 300
           SLKLTFISPGQKVIFSSQAICAPDPVTCNATHMTLTIPEFPGKLKSVSFENQNIDVSQLH
Sbjct: 241 SLKLTFISPGQKVIFSSQAICAPDPVTCNATHMTLTIPEFPGKLKSVSFENQNIDVSQLH 300

Query: 301 DNGIDLEATNGMKLHFSKTLLKTKLSEKCLLHQFYLASLKLTFLLRPETVSMVIYPECLC 360
           DNGIDLEATNGMKLHFSKTLLKTKLSEKCLLHQFYLASLKLTFLLRPETVSMVIYPECLC
Sbjct: 301 DNGIDLEATNGMKLHFSKTLLKTKLSEKCLLHQFYLASLKLTFLLRPETVSMVIYPECLC 360

Query: 361 ESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIP 420
           ESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIP
Sbjct: 361 ESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIP 420

Query: 421 LNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVES 480
           LNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVES
Sbjct: 421 LNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVES 480

Query: 481 LTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKL 540
           LTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKL
Sbjct: 481 LTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKL 540

Query: 541 VLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAF 600
           VLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAF
Sbjct: 541 VLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAF 600

Query: 601 VSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPI 660
           VSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPI
Sbjct: 601 VSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPI 660

Query: 661 LLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKAVAAV 720
           LLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKAVAAV
Sbjct: 661 LLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAGDVGSKAVAAV 720

Query: 721 AAFAGVVATLGFIYYLYEKRTVSNH 745
           AAFAGVVATLGFIYYLYEKRTVSNH
Sbjct: 721 AAFAGVVATLGFIYYLYEKRTVSNH 745


>gi|10863987 zona pellucida glycoprotein 4 preproprotein [Homo
           sapiens]
          Length = 540

 Score =  211 bits (537), Expect = 2e-54
 Identities = 121/304 (39%), Positives = 170/304 (55%), Gaps = 16/304 (5%)

Query: 372 CTQDGFMDVEVYSYQTQPALDLGTLRVG---NSSCQPVFEAQSQGLVRFHIPLNGCGTRY 428
           CT++G   + V    T P L L ++R+    +S+C PV   Q+   V F  P   CGT  
Sbjct: 189 CTREGHFSIAVSRNVTSPPLLLDSVRLALRNDSACNPVMATQA--FVLFQFPFTSCGTTR 246

Query: 429 KFEDDKVVYENEIHALWTDFPPSK--ISRDSEFRMTVKCSYS--RNDMLLNINVESLTPP 484
           +   D+ VYENE+ A       S+  ++RDS FR+ V CSYS   N + +N+ V +L PP
Sbjct: 247 QITGDRAVYENELVATRDVKNGSRGSVTRDSIFRLHVSCSYSVSSNSLPINVQVFTLPPP 306

Query: 485 VASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDD 544
               + GP TL LQ   D +Y   YG  +YP+V+ LR PIY+EV +L+R DP + L+L  
Sbjct: 307 FPETQPGPLTLELQIAKDKNYGSYYGVGDYPVVKLLRDPIYVEVSILHRTDPYLGLLLQQ 366

Query: 545 CWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSS--VTHPDHYQRFDMKAFAFVS 602
           CWAT + DP S PQW ++V GC Y  DNYQT   PV  +  +  P H+QRF +  F+FV+
Sbjct: 367 CWATPSTDPLSQPQWPILVKGCPYIGDNYQTQLIPVQKALDLPFPSHHQRFSIFTFSFVN 426

Query: 603 ---EAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGP 659
              E   L   V+ HCS  +C     ++P C VTCP  SR R    +++    +VS  GP
Sbjct: 427 PTVEKQALRGPVHLHCSVSVCQ--PAETPSCVVTCPDLSRRRNFDNSSQNTTASVSSKGP 484

Query: 660 ILLL 663
           ++LL
Sbjct: 485 MILL 488


>gi|66348148 zona pellucida glycoprotein 1 [Homo sapiens]
          Length = 638

 Score =  160 bits (405), Expect = 4e-39
 Identities = 91/271 (33%), Positives = 143/271 (52%), Gaps = 17/271 (6%)

Query: 401 SSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYEN----EIHALWTDFPPSKISRD 456
           +SC P     ++  V F+ PL  CGT  +   D+++YEN     IH      P   I+RD
Sbjct: 312 TSCSPT--QHTEAFVVFYFPLTHCGTTMQVAGDQLIYENWLVSGIHI--QKGPQGSITRD 367

Query: 457 SEFRMTVKCSYSRNDML-LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYP 515
           S F++ V+C ++ +D L +  ++     P    + GP  L L+   D ++   YGE++YP
Sbjct: 368 STFQLHVRCVFNASDFLPIQASIFPPPSPAPMTQPGPLRLELRIAKDETFSSYYGEDDYP 427

Query: 516 LVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQT 575
           +VR LR+P+++EVR+L R DPN+ L+L  CW   + +P   PQW ++ DGC +  D+Y+T
Sbjct: 428 IVRLLREPVHVEVRLLQRTDPNLVLLLHQCWGAPSANPFQQPQWPILSDGCPFKGDSYRT 487

Query: 576 TFHPVGSSVTHPDHYQRFDMKAFAFVSEA--HVLSSLVYFHCSALICNRLSPDSPLCSVT 633
               +  +     HYQRF +  FA +       L  LVY  CS   C+    ++  CS  
Sbjct: 488 QMVALDGATPFQSHYQRFTVATFALLDSGSQRALRGLVYLFCSTSACHTSGLET--CSTA 545

Query: 634 CPV-SSRHRRATG---ATEAEKMTVSLPGPI 660
           C   ++R RR++G    T   +  VS PGP+
Sbjct: 546 CSTGTTRQRRSSGHRNDTARPQDIVSSPGPV 576


>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
          Length = 607

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 89/326 (27%), Positives = 142/326 (43%), Gaps = 38/326 (11%)

Query: 368 TGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPVFEAQSQGLVRFHIPLNGCGTR 427
           T   C+ D    +   SY      +   L++ + +C+P    +   +V F +PLNGCGT 
Sbjct: 273 TSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPTCRP----KLSNVVEFSVPLNGCGTI 328

Query: 428 YKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVESLTPPVAS 487
            K ED  + Y N I           I+R  + ++ VKC    N  +  I +       + 
Sbjct: 329 RKVEDQSITYTN-IITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYITEDDVIQSQ 387

Query: 488 VKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWA 547
             LG +   +  +  NS+++   E+ Y +   L Q ++++V  L+  DPN+ + LD C A
Sbjct: 388 NALGKYNTSMALFESNSFEKTILESPYYV--DLNQTLFVQVS-LHTSDPNLVVFLDTCRA 444

Query: 548 TSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVL 607
           + T D  S P ++++  GC+ D        +P+        HY RF   AF F+      
Sbjct: 445 SPTSDFAS-PTYDLIKSGCSRD---ETCKVYPLFG------HYGRFQFNAFKFLRS---- 490

Query: 608 SSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVSLPGPILLLSDDS 667
            S VY  C  LIC+  S     C+  C   SR +R   + + +  T S+ GPI L  D S
Sbjct: 491 MSSVYLQCKVLICDS-SDHQSRCNQGC--VSRSKRDISSYKWK--TDSIIGPIRLKRDRS 545

Query: 668 SFRGVGSSDLKASGSSGEKSRSETGE 693
                      ASG+SG +  +   E
Sbjct: 546 -----------ASGNSGFQHETHAEE 560


>gi|134268640 tectorin alpha precursor [Homo sapiens]
          Length = 2155

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 70/305 (22%), Positives = 132/305 (43%), Gaps = 33/305 (10%)

Query: 366  IVTGELCTQDGFMDVEVYSYQT-QPALDLGTLRVGNSSCQPVFEAQSQGLVRFHI--PLN 422
            I+  E+  +   M+V +   +  Q   +   +R+ +  C  +   + +  + F I     
Sbjct: 1799 IIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGI---EGEDFISFQINNTKG 1855

Query: 423  GCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVESLT 482
             CG   +     ++Y+N +     +   + I+RD    +   C+Y   ++ + I+++S+ 
Sbjct: 1856 NCGNIVQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAY---ELDIKISLDSVV 1912

Query: 483  PPVASV-------KLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDD 535
             P+ SV       + G F   +  Y + SY+ PY + E  L    R  +Y+ V V+  D 
Sbjct: 1913 KPMLSVINLTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTT--RDVLYVGVFVVGADA 1970

Query: 536  PNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDM 595
             ++ L L+ C+AT T D +   ++ ++  GC    DN       +G          RF +
Sbjct: 1971 THLILTLNKCYATPTRDSNDKLRYFIIEGGCQNLKDN------TIGIEENAVSLTCRFHV 2024

Query: 596  KAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTCPVSSRHRRATGATEAEKMTVS 655
              F F+ +       V+ HC+  +C+    +   C +TCP +S  R AT  T+  K  + 
Sbjct: 2025 TVFKFIGD----YDEVHLHCAVSLCD---SEKYSCKITCPHNS--RIATDYTKEPKEQII 2075

Query: 656  LPGPI 660
              GPI
Sbjct: 2076 SVGPI 2080


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 33/271 (12%)

Query: 399  GNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSE 458
            G   C+P     +  LV F IP +GCGT  + ++D + Y N + A  +      I R ++
Sbjct: 1407 GYYECRPQI---TPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG---GIIKRRTD 1460

Query: 459  FRMTVKCSYSRNDML-------LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGE 511
             R+ V C   +N  +         I+V + T  V  V+ G F + +  Y  +S+  P   
Sbjct: 1461 LRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTS 1520

Query: 512  NEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLD 571
              Y +   L Q +Y++  +L+  D  + L +D C A+   +  +   ++++  GC  D  
Sbjct: 1521 RPYYV--DLNQDLYVQAEILH-SDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRD-- 1575

Query: 572  NYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCS 631
                T+ P  S         RF  +AF F++        VY  C  ++C    P S  C 
Sbjct: 1576 ---DTYGPYSSPSL---RIARFRFRAFHFLNR----FPSVYLRCKMVVCRAYDPSS-RCY 1624

Query: 632  VTCPVSSRHRRATGATEAEKMTVSLPGPILL 662
              C +  R +R  G+ + EK+ V L GPI L
Sbjct: 1625 RGCVL--RSKRDVGSYQ-EKVDVVL-GPIQL 1651


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 33/271 (12%)

Query: 399  GNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSE 458
            G   C+P     +  LV F IP +GCGT  + ++D + Y N + A  +      I R ++
Sbjct: 1533 GYYECRPQI---TPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG---GIIKRRTD 1586

Query: 459  FRMTVKCSYSRNDML-------LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGE 511
             R+ V C   +N  +         I+V + T  V  V+ G F + +  Y  +S+  P   
Sbjct: 1587 LRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTS 1646

Query: 512  NEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLD 571
              Y +   L Q +Y++  +L+  D  + L +D C A+   +  +   ++++  GC  D  
Sbjct: 1647 RPYYV--DLNQDLYVQAEILH-SDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRD-- 1701

Query: 572  NYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCS 631
                T+ P  S         RF  +AF F++        VY  C  ++C    P S  C 
Sbjct: 1702 ---DTYGPYSSPSL---RIARFRFRAFHFLNR----FPSVYLRCKMVVCRAYDPSS-RCY 1750

Query: 632  VTCPVSSRHRRATGATEAEKMTVSLPGPILL 662
              C +  R +R  G+ + EK+ V L GPI L
Sbjct: 1751 RGCVL--RSKRDVGSYQ-EKVDVVL-GPIQL 1777


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 33/271 (12%)

Query: 399  GNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSE 458
            G   C+P     +  LV F IP +GCGT  + ++D + Y N + A  +      I R ++
Sbjct: 2148 GYYECRPQI---TPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG---GIIKRRTD 2201

Query: 459  FRMTVKCSYSRNDML-------LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGE 511
             R+ V C   +N  +         I+V + T  V  V+ G F + +  Y  +S+  P   
Sbjct: 2202 LRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTS 2261

Query: 512  NEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLD 571
              Y +   L Q +Y++  +L+  D  + L +D C A+   +  +   ++++  GC  D  
Sbjct: 2262 RPYYV--DLNQDLYVQAEILH-SDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRD-- 2316

Query: 572  NYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCS 631
                T+ P  S         RF  +AF F++        VY  C  ++C    P S  C 
Sbjct: 2317 ---DTYGPYSSPSL---RIARFRFRAFHFLNR----FPSVYLRCKMVVCRAYDPSS-RCY 2365

Query: 632  VTCPVSSRHRRATGATEAEKMTVSLPGPILL 662
              C +  R +R  G+ + EK+ V L GPI L
Sbjct: 2366 RGCVL--RSKRDVGSYQ-EKVDVVL-GPIQL 2392


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 33/271 (12%)

Query: 399  GNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSE 458
            G   C+P     +  LV F IP +GCGT  + ++D + Y N + A  +      I R ++
Sbjct: 2158 GYYECRPQI---TPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG---GIIKRRTD 2211

Query: 459  FRMTVKCSYSRNDML-------LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGE 511
             R+ V C   +N  +         I+V + T  V  V+ G F + +  Y  +S+  P   
Sbjct: 2212 LRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTS 2271

Query: 512  NEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLD 571
              Y +   L Q +Y++  +L+  D  + L +D C A+   +  +   ++++  GC  D  
Sbjct: 2272 RPYYV--DLNQDLYVQAEILH-SDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRD-- 2326

Query: 572  NYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCS 631
                T+ P  S         RF  +AF F++        VY  C  ++C    P S  C 
Sbjct: 2327 ---DTYGPYSSPSL---RIARFRFRAFHFLNR----FPSVYLRCKMVVCRAYDPSS-RCY 2375

Query: 632  VTCPVSSRHRRATGATEAEKMTVSLPGPILL 662
              C +  R +R  G+ + EK+ V L GPI L
Sbjct: 2376 RGCVL--RSKRDVGSYQ-EKVDVVL-GPIQL 2402


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 33/271 (12%)

Query: 399  GNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKISRDSE 458
            G   C+P     +  LV F IP +GCGT  + ++D + Y N + A  +      I R ++
Sbjct: 1530 GYYECRPQI---TPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG---GIIKRRTD 1583

Query: 459  FRMTVKCSYSRNDML-------LNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGE 511
             R+ V C   +N  +         I+V + T  V  V+ G F + +  Y  +S+  P   
Sbjct: 1584 LRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTS 1643

Query: 512  NEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLD 571
              Y +   L Q +Y++  +L+  D  + L +D C A+   +  +   ++++  GC  D  
Sbjct: 1644 RPYYV--DLNQDLYVQAEILH-SDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRD-- 1698

Query: 572  NYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCS 631
                T+ P  S         RF  +AF F++        VY  C  ++C    P S  C 
Sbjct: 1699 ---DTYGPYSSPSL---RIARFRFRAFHFLNR----FPSVYLRCKMVVCRAYDPSS-RCY 1747

Query: 632  VTCPVSSRHRRATGATEAEKMTVSLPGPILL 662
              C +  R +R  G+ + EK+ V L GPI L
Sbjct: 1748 RGCVL--RSKRDVGSYQ-EKVDVVL-GPIQL 1774


>gi|22749297 oncoprotein-induced transcript 3 [Homo sapiens]
          Length = 545

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 67/257 (26%), Positives = 110/257 (42%), Gaps = 28/257 (10%)

Query: 400 NSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSK---ISRD 456
           N+SC+ V       ++     L  CGT     +DK+V  N +  L    P S    I R 
Sbjct: 291 NTSCRGVSNGTHVNIL---FSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRT 347

Query: 457 SEFRMTVKCSYSRNDMLLNINVESLTPP---VASVKLGPFTLILQSYPDNSYQQPYGENE 513
           S+  + V C + R   +    V +L      + S   G F   L+ + DN +++PY E  
Sbjct: 348 SKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYRE-A 406

Query: 514 YPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNY 573
            P ++ LR  +Y  +  +      ++ +++ C+AT T   D   ++ ++ DGC  D D+ 
Sbjct: 407 LPTLK-LRDSLYFGIEPVVHVS-GLESLVESCFATPTSKIDEVLKYYLIRDGCVSD-DSV 463

Query: 574 QTTFHPVGSSVTHPDHY-QRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCSV 632
           +          T  DH  + F +  F FV + H     V+ HC  L+C  L   S  C+ 
Sbjct: 464 K--------QYTSRDHLAKHFQVPVFKFVGKDH---KEVFLHCRVLVCGVLDERS-RCAQ 511

Query: 633 TCPVSSRHRRATGATEA 649
            C    R RR  G  ++
Sbjct: 512 GC--HRRMRRGAGGEDS 526


>gi|119220571 zymogen granule membrane glycoprotein 2 isoform 2
           [Homo sapiens]
          Length = 534

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 55/238 (23%), Positives = 104/238 (43%), Gaps = 27/238 (11%)

Query: 402 SCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKV--VYENEIHALWTDFPPSKISRDSEF 459
           +C  + + + +  V    P+     R   E ++   +Y+N + +L  DF    I RD+  
Sbjct: 257 NCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL-SLVNDF----IIRDTIL 311

Query: 460 RMTVKCSYSRNDMLLNINVESLTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEY 514
            +  +C+Y   DM +++   +L P V+S+ +     G F + +  + D +Y  PY  +  
Sbjct: 312 NINFQCAYPL-DMKVSLQA-ALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAV 369

Query: 515 PLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQ 574
            L   +   +Y+   +   D     LVL +C+AT T D     ++ ++ + C+   D   
Sbjct: 370 ELS--VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRD--- 424

Query: 575 TTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCS 631
           +T H   +  +      RF ++ F F         LV+ HC   +C+ L+    P CS
Sbjct: 425 STIHVEENGQSSE---SRFSVQMFMFAGH----YDLVFLHCEIHLCDSLNEQCQPSCS 475


>gi|119220569 zymogen granule membrane glycoprotein 2 isoform 1
           [Homo sapiens]
          Length = 537

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 55/238 (23%), Positives = 104/238 (43%), Gaps = 27/238 (11%)

Query: 402 SCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKV--VYENEIHALWTDFPPSKISRDSEF 459
           +C  + + + +  V    P+     R   E ++   +Y+N + +L  DF    I RD+  
Sbjct: 260 NCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL-SLVNDF----IIRDTIL 314

Query: 460 RMTVKCSYSRNDMLLNINVESLTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEY 514
            +  +C+Y   DM +++   +L P V+S+ +     G F + +  + D +Y  PY  +  
Sbjct: 315 NINFQCAYPL-DMKVSLQA-ALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAV 372

Query: 515 PLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQ 574
            L   +   +Y+   +   D     LVL +C+AT T D     ++ ++ + C+   D   
Sbjct: 373 ELS--VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRD--- 427

Query: 575 TTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCS 631
           +T H   +  +      RF ++ F F         LV+ HC   +C+ L+    P CS
Sbjct: 428 STIHVEENGQSSE---SRFSVQMFMFAGH----YDLVFLHCEIHLCDSLNEQCQPSCS 478


>gi|119220573 zymogen granule membrane glycoprotein 2 isoform 4
           [Homo sapiens]
          Length = 387

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 55/238 (23%), Positives = 104/238 (43%), Gaps = 27/238 (11%)

Query: 402 SCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKV--VYENEIHALWTDFPPSKISRDSEF 459
           +C  + + + +  V    P+     R   E ++   +Y+N + +L  DF    I RD+  
Sbjct: 110 NCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL-SLVNDF----IIRDTIL 164

Query: 460 RMTVKCSYSRNDMLLNINVESLTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEY 514
            +  +C+Y   DM +++   +L P V+S+ +     G F + +  + D +Y  PY  +  
Sbjct: 165 NINFQCAYPL-DMKVSLQA-ALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAV 222

Query: 515 PLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQ 574
            L   +   +Y+   +   D     LVL +C+AT T D     ++ ++ + C+   D   
Sbjct: 223 ELS--VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRD--- 277

Query: 575 TTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCS 631
           +T H   +  +      RF ++ F F         LV+ HC   +C+ L+    P CS
Sbjct: 278 STIHVEENGQSSE---SRFSVQMFMFAGH----YDLVFLHCEIHLCDSLNEQCQPSCS 328


>gi|119220572 zymogen granule membrane glycoprotein 2 isoform 3
           [Homo sapiens]
          Length = 390

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 55/238 (23%), Positives = 104/238 (43%), Gaps = 27/238 (11%)

Query: 402 SCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKV--VYENEIHALWTDFPPSKISRDSEF 459
           +C  + + + +  V    P+     R   E ++   +Y+N + +L  DF    I RD+  
Sbjct: 113 NCSSILQTEERNWVSVTSPVQASACRNILERNQTHAIYKNTL-SLVNDF----IIRDTIL 167

Query: 460 RMTVKCSYSRNDMLLNINVESLTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEY 514
            +  +C+Y   DM +++   +L P V+S+ +     G F + +  + D +Y  PY  +  
Sbjct: 168 NINFQCAYPL-DMKVSLQA-ALQPIVSSLNVSVDGNGEFIVRMALFQDQNYTNPYEGDAV 225

Query: 515 PLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQ 574
            L   +   +Y+   +   D     LVL +C+AT T D     ++ ++ + C+   D   
Sbjct: 226 ELS--VESVLYVGAILEQGDTSRFNLVLRNCYATPTEDKADLVKYFIIRNSCSNQRD--- 280

Query: 575 TTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCS 631
           +T H   +  +      RF ++ F F         LV+ HC   +C+ L+    P CS
Sbjct: 281 STIHVEENGQSSE---SRFSVQMFMFAGH----YDLVFLHCEIHLCDSLNEQCQPSCS 331


>gi|160358850 zona pellucida glycoprotein 3 isoform 1 precursor
           [Homo sapiens]
          Length = 424

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 62/300 (20%), Positives = 125/300 (41%), Gaps = 34/300 (11%)

Query: 347 PETVSMVIYPECLCESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRVGNSSCQPV 406
           PET    +  EC   + + +V+ +L             + T   +    L +G  +C+P+
Sbjct: 35  PETSVQPVLVECQEATLMVMVSKDL-------------FGTGKLIRAADLTLGPEACEPL 81

Query: 407 FEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKIS--RDSEFRMTVK 464
               ++ +VRF + L+ CG   +  DD +VY   +  L    P   +S  R +   + ++
Sbjct: 82  VSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFL--LHDPRPVGNLSIVRTNRAEIPIE 139

Query: 465 CSYSRNDMLLNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPI 524
           C Y R     N++ +++ P     +   F+    ++     ++ +   +      L    
Sbjct: 140 CRYPRQG---NVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAA 196

Query: 525 YMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVD--GCAYD-LDNYQTTFHPVG 581
           +++  +       ++L +D C AT T D ++ P ++ +VD  GC  D L +  + F    
Sbjct: 197 HLQAEIHTGSHVPLRLFVDHCVATPTPDQNASP-YHTIVDFHGCLVDGLTDASSAFKVPR 255

Query: 582 SSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALI-CNRLSPD--SPLCSVTCPVSS 638
                PD  Q F +  F F +++    +++Y  C   +      PD  +  CS + P +S
Sbjct: 256 PG---PDTLQ-FTVDVFHFANDSR---NMIYITCHLKVTLAEQDPDELNKACSFSKPSNS 308


>gi|38327649 zona pellucida glycoprotein 3 isoform 2 [Homo sapiens]
          Length = 373

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 54/251 (21%), Positives = 109/251 (43%), Gaps = 21/251 (8%)

Query: 396 LRVGNSSCQPVFEAQSQGLVRFHIPLNGCGTRYKFEDDKVVYENEIHALWTDFPPSKIS- 454
           L +G  +C+P+    ++ +VRF + L+ CG   +  DD +VY   +  L    P   +S 
Sbjct: 20  LTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFL--LHDPRPVGNLSI 77

Query: 455 -RDSEFRMTVKCSYSRNDMLLNINVESLTPPVASVKLGPFTLILQSYPDNSYQQPYGENE 513
            R +   + ++C Y R     N++ +++ P     +   F+    ++     ++ +   +
Sbjct: 78  VRTNRAEIPIECRYPRQG---NVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEK 134

Query: 514 YPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVD--GCAYD-L 570
                 L    +++  +       ++L +D C AT T D ++ P ++ +VD  GC  D L
Sbjct: 135 RSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASP-YHTIVDFHGCLVDGL 193

Query: 571 DNYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALI-CNRLSPD--S 627
            +  + F         PD  Q F +  F F +++    +++Y  C   +      PD  +
Sbjct: 194 TDASSAFKVPRPG---PDTLQ-FTVDVFHFANDSR---NMIYITCHLKVTLAEQDPDELN 246

Query: 628 PLCSVTCPVSS 638
             CS + P +S
Sbjct: 247 KACSFSKPSNS 257


>gi|56550049 uromodulin precursor [Homo sapiens]
          Length = 640

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 53/219 (24%), Positives = 92/219 (42%), Gaps = 31/219 (14%)

Query: 424 CGTRYKFEDDKVVYENEIHALWTD---FPPSKISRDSEFRMTVKCSYSRNDMLLNINVES 480
           CGT        V+  NE HA +++        I RD   ++   CSY   DM +++   +
Sbjct: 389 CGT--------VLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPL-DMKVSLKT-A 438

Query: 481 LTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDD 535
           L P V+++ +     G FT+ +  +   SY QPY  +   L       +Y+   +   D 
Sbjct: 439 LQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLST--EAFLYVGTMLDGGDL 496

Query: 536 PNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDM 595
               L++ +C+AT + +     ++ ++ D C +  D+         SS        RF +
Sbjct: 497 SRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESS------QGRFSV 550

Query: 596 KAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCSVT 633
           + F F         LVY HC   +C+ ++    P CS T
Sbjct: 551 QMFRFAGNY----DLVYLHCEVYLCDTMNEKCKPTCSGT 585


>gi|59850812 uromodulin precursor [Homo sapiens]
          Length = 640

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 53/219 (24%), Positives = 92/219 (42%), Gaps = 31/219 (14%)

Query: 424 CGTRYKFEDDKVVYENEIHALWTD---FPPSKISRDSEFRMTVKCSYSRNDMLLNINVES 480
           CGT        V+  NE HA +++        I RD   ++   CSY   DM +++   +
Sbjct: 389 CGT--------VLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPL-DMKVSLKT-A 438

Query: 481 LTPPVASVKL-----GPFTLILQSYPDNSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDD 535
           L P V+++ +     G FT+ +  +   SY QPY  +   L       +Y+   +   D 
Sbjct: 439 LQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLST--EAFLYVGTMLDGGDL 496

Query: 536 PNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDM 595
               L++ +C+AT + +     ++ ++ D C +  D+         SS        RF +
Sbjct: 497 SRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESS------QGRFSV 550

Query: 596 KAFAFVSEAHVLSSLVYFHCSALICNRLSPD-SPLCSVT 633
           + F F         LVY HC   +C+ ++    P CS T
Sbjct: 551 QMFRFAGNY----DLVYLHCEVYLCDTMNEKCKPTCSGT 585


>gi|28372569 zona pellucida-like domain containing 1 [Homo sapiens]
          Length = 431

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 58/229 (25%), Positives = 95/229 (41%), Gaps = 21/229 (9%)

Query: 446 TDFPPSKISRDSEFRMTVKCSYSRNDMLLNINVESLTPPVA-SVKLGPF--TLILQSYPD 502
           T  PP+ IS          CSY    ++ N  + S +  ++     G F  TL L  Y D
Sbjct: 152 TPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYND 211

Query: 503 NSYQQPYGENEYPLVRFLRQPIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVV 562
           ++Y Q        L   L+  ++  V+  N D     +++D C+ T + +P+   ++++ 
Sbjct: 212 STYNQQLIIPSIGLP--LKTKVFAAVQATNLDG-RWNVLMDYCYTTPSGNPNDDIRYDLF 268

Query: 563 VDGCAYDLDNYQTTFHPVGSSVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNR 622
           +  C  D    QTT    G S        RF  + F FV   +   S V+ HC   +C  
Sbjct: 269 LS-CDKDP---QTTVIENGRS-----QRGRFSFEVFRFVKHKNQKMSTVFLHCVTKLCR- 318

Query: 623 LSPDSPLCSVTCPVSSRH---RRATGATEAEKMTVSL-PGPILLLSDDS 667
            + D P     C    R    RR T + ++   +  L  GPI+  SD++
Sbjct: 319 -ADDCPFLMPICSHRERRDAGRRTTWSPQSSSGSAVLSAGPIITRSDET 366


>gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens]
          Length = 1318

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 14/104 (13%)

Query: 531  LNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHY 590
            L R   N+K+VL +CWAT + +      ++ + + C   + N  T     G+S     + 
Sbjct: 1143 LYRQKSNLKVVLTECWATPSSNARDPITFSFINNSC--PVPNTYTNVIENGNS-----NK 1195

Query: 591  QRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTC 634
             +F ++ F+F+++     S+VY HC   +C  +      C + C
Sbjct: 1196 AQFKLRIFSFIND-----SIVYLHCKLRVC--MESPGATCKINC 1232


>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 1446

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 14/104 (13%)

Query: 531  LNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGSSVTHPDHY 590
            L R   N+K+VL +CWAT + +      ++ + + C   + N  T     G+S     + 
Sbjct: 1271 LYRQKSNLKVVLTECWATPSSNARDPITFSFINNSC--PVPNTYTNVIENGNS-----NK 1323

Query: 591  QRFDMKAFAFVSEAHVLSSLVYFHCSALICNRLSPDSPLCSVTC 634
             +F ++ F+F+++     S+VY HC   +C  +      C + C
Sbjct: 1324 AQFKLRIFSFIND-----SIVYLHCKLRVC--MESPGATCKINC 1360


>gi|56682966 transforming growth factor, beta receptor III [Homo
           sapiens]
          Length = 851

 Score = 38.1 bits (87), Expect = 0.030
 Identities = 46/221 (20%), Positives = 93/221 (42%), Gaps = 25/221 (11%)

Query: 420 PLNGCGTRYKFED-DKVVYENEI---------HALWTDFPPSKISRDSEFRMTVK----C 465
           PLNGCGTR ++   D VVY N I          + W D      S D+ F   +      
Sbjct: 501 PLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDAS 560

Query: 466 SYSRNDMLL-NINVESLTPPVASVKL--GPFTLILQSYPDNSYQQPYGENEYPLVRFLRQ 522
            ++R ++++ N +++ +  P +  +   G  T  ++ Y  + +  P  +  + +      
Sbjct: 561 LFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVP-SQGVFSVPE--NG 617

Query: 523 PIYMEVRVLNRDDPNIKLVLDDCWATSTMDPDSFPQWNVVVDGCAYDLDNYQTTFHPVGS 582
            +Y+EV V  + +  +   +  C+ +   +PD    + ++ + C  D    ++       
Sbjct: 618 HVYVEVSV-TKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKD----ESVKFYSPK 672

Query: 583 SVTHPDHYQRFDMKAFAFVSEAHVLSSLVYFHCSALICNRL 623
            V  P      D K F+FV +    +SL++  C   +C ++
Sbjct: 673 RVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKM 713


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 31.6 bits (70), Expect = 2.8
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 10/87 (11%)

Query: 630 CSVTCPVSSRHRRATGATEAEKMTVSLPGPILLLSDDSSFRGVGSS---DLKASGSSGEK 686
           CS T   ++R  R   A  A  +   +  P+L     ++  G GSS    +  S ++G +
Sbjct: 4   CSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSR 63

Query: 687 SRSET-------GEEVGSRGAMDTKGH 706
           S SE+       GEEV  RG +  + H
Sbjct: 64  SDSESEEEDLPVGEEVCKRGYLRKQKH 90


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 1/69 (1%)

Query: 638 SRHRRATGATEAEKMTVSLPGPILLLSDDSSFRGVGSSDLKASGSSGEKSRSETGEEVGS 697
           SR R ++ ++ +   T S  G     S  SS R   SS    SGSS   S S T     S
Sbjct: 573 SRSRSSSSSSSSSSSTSSSSGSSSS-SGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSES 631

Query: 698 RGAMDTKGH 706
           R     +GH
Sbjct: 632 RSRSRGRGH 640


>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
           [Homo sapiens]
          Length = 486

 Score = 30.8 bits (68), Expect = 4.8
 Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 3/58 (5%)

Query: 675 SDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAG-DVGSKAVAAVAAFAGVVATLG 731
           S L +SGSS   S S +   + S GA+ T    TAG +VGS  +A +AA  G + + G
Sbjct: 292 SVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGS--LAGMAALNGGLGSSG 347


>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 482

 Score = 30.8 bits (68), Expect = 4.8
 Identities = 23/58 (39%), Positives = 32/58 (55%), Gaps = 3/58 (5%)

Query: 675 SDLKASGSSGEKSRSETGEEVGSRGAMDTKGHKTAG-DVGSKAVAAVAAFAGVVATLG 731
           S L +SGSS   S S +   + S GA+ T    TAG +VGS  +A +AA  G + + G
Sbjct: 288 SVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGS--LAGMAALNGGLGSSG 343


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score = 30.0 bits (66), Expect = 8.1
 Identities = 16/65 (24%), Positives = 29/65 (44%)

Query: 339 LKLTFLLRPETVSMVIYPECLCESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRV 398
           + L  L  P  ++  I P CL  +  ++V G++CT  G+ + + Y  Q     +     +
Sbjct: 258 IALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPII 317

Query: 399 GNSSC 403
            N  C
Sbjct: 318 SNDVC 322


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score = 30.0 bits (66), Expect = 8.1
 Identities = 16/65 (24%), Positives = 29/65 (44%)

Query: 339 LKLTFLLRPETVSMVIYPECLCESPVSIVTGELCTQDGFMDVEVYSYQTQPALDLGTLRV 398
           + L  L  P  ++  I P CL  +  ++V G++CT  G+ + + Y  Q     +     +
Sbjct: 258 IALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPII 317

Query: 399 GNSSC 403
            N  C
Sbjct: 318 SNDVC 322


>gi|31543535 R3H domain containing 1 [Homo sapiens]
          Length = 1099

 Score = 30.0 bits (66), Expect = 8.1
 Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 2/80 (2%)

Query: 637 SSRHRRATGATEAEKMTVSLPGPILLLSDDSSFRGVGSSDLKASGSSGEK--SRSETGEE 694
           S R   +  ++   ++  S P P      DSS R +  +  KAS  SG    +R ++   
Sbjct: 337 SGRSTNSHQSSTENELKYSEPRPWSSTDSDSSLRNLKPAVTKASSFSGISVLTRGDSSGS 396

Query: 695 VGSRGAMDTKGHKTAGDVGS 714
             S G +   G +++G VGS
Sbjct: 397 SKSIGRLSKTGSESSGSVGS 416


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,112,547
Number of Sequences: 37866
Number of extensions: 1298277
Number of successful extensions: 3017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2979
Number of HSP's gapped (non-prelim): 35
length of query: 745
length of database: 18,247,518
effective HSP length: 110
effective length of query: 635
effective length of database: 14,082,258
effective search space: 8942233830
effective search space used: 8942233830
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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