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Search of human proteins with 4507499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 790 0.0
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 780 0.0
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 608 e-174
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 598 e-171
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 119 4e-27
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 116 4e-26
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 115 8e-26
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 114 2e-25
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 114 2e-25
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 114 2e-25
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 107 1e-23
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 107 2e-23
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 105 9e-23
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 104 1e-22
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 104 1e-22
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 104 1e-22
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 104 1e-22
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 100 2e-21
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 100 3e-21
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 100 3e-21
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 99 6e-21
gi|38201714 ELAV-like 1 [Homo sapiens] 97 2e-20
gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens] 93 4e-19
gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens] 93 4e-19
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 83 4e-16
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 83 4e-16
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 83 4e-16
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 81 2e-15
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 81 2e-15
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 78 1e-14
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 790 bits (2041), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD 60
MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRD 60
Query: 61 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF 120
AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF
Sbjct: 61 AAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPF 120
Query: 121 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP 180
GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP
Sbjct: 121 GKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAP 180
Query: 181 KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK 240
KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK
Sbjct: 181 KSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK 240
Query: 241 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY 300
GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY
Sbjct: 241 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVY 300
Query: 301 GNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIP 360
GNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIP
Sbjct: 301 GNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIP 360
Query: 361 PPNQAGYGMASYQTQ 375
PPNQAGYGMASYQTQ
Sbjct: 361 PPNQAGYGMASYQTQ 375
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 780 bits (2013), Expect = 0.0
Identities = 375/392 (95%), Positives = 375/392 (95%), Gaps = 17/392 (4%)
Query: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE----------------- 43
MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE
Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQ 60
Query: 44 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGD 103
HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGD
Sbjct: 61 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGD 120
Query: 104 LSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL 163
LSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL
Sbjct: 121 LSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWL 180
Query: 164 GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQ 223
GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQ
Sbjct: 181 GGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQ 240
Query: 224 TFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTK 283
TFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTK
Sbjct: 241 TFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTK 300
Query: 284 NFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG 343
NFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG
Sbjct: 301 NFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG 360
Query: 344 GFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ 375
GFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
Sbjct: 361 GFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ 392
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 608 bits (1569), Expect = e-174
Identities = 300/378 (79%), Positives = 327/378 (86%), Gaps = 10/378 (2%)
Query: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAA 63
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI + NDPYCFVEF+EHR AAA
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAA 61
Query: 64 ALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKI 123
ALAAMNGRKI+GKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIK+AFAPFG+I
Sbjct: 62 ALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRI 121
Query: 124 SDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKST 183
SDARVVKDMATGKSKGYGFVSF+NK DAENAI MGGQWLGGRQIRTNWATRKPPAPKST
Sbjct: 122 SDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKST 181
Query: 184 QENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYS 243
E+NTKQL +++VVNQSSP NCTVYCGG+ SGLT+QLMRQTFSPFGQIMEIRVFP+KGYS
Sbjct: 182 YESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYS 241
Query: 244 FVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ---QVDYSQ-WGQWSQV 299
FVRF++HESAAHAIVSVNGTTIEGHVVKCYWGKE+ DM Q Q+ Y Q +GQW Q
Sbjct: 242 FVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQW 301
Query: 300 YGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-GFGAQPPQGQAPPPV 358
YGN QQ GQYM NGWQVP YG+YGQ WNQQGF QS SA WMG +G QPPQGQ +
Sbjct: 302 YGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPNYGVQPPQGQNGSML 360
Query: 359 IPPPNQ-AGYGMASYQTQ 375
PNQ +GY +A Y+TQ
Sbjct: 361 ---PNQPSGYRVAGYETQ 375
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 598 bits (1542), Expect = e-171
Identities = 299/389 (76%), Positives = 327/389 (84%), Gaps = 21/389 (5%)
Query: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAA 63
+D P+TLYVGNLSRDVTE LILQLFSQIGPCK+CKMI + NDPYCFVEF+EHR AAA
Sbjct: 2 EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAA 61
Query: 64 ALAAMNGRKILGKEVKVNWATTPSSQKKDTSN-----------HFHVFVGDLSPEITTED 112
ALAAMNGRKI+GKEVKVNWATTPSSQKKDTS+ HFHVFVGDLSPEITTED
Sbjct: 62 ALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTED 121
Query: 113 IKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNW 172
IK+AFAPFG+ISDARVVKDMATGKSKGYGFVSF+NK DAENAI MGGQWLGGRQIRTNW
Sbjct: 122 IKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNW 181
Query: 173 ATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIM 232
ATRKPPAPKST E+NTKQL +++VVNQSSP NCTVYCGG+ SGLT+QLMRQTFSPFGQIM
Sbjct: 182 ATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIM 241
Query: 233 EIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQ---QVD 289
EIRVFP+KGYSFVRF++HESAAHAIVSVNGTTIEGHVVKCYWGKE+ DM Q Q+
Sbjct: 242 EIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIG 301
Query: 290 YSQ-WGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMG-GFGA 347
Y Q +GQW Q YGN QQ GQYM NGWQVP YG+YGQ WNQQGF QS SA WMG +G
Sbjct: 302 YPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQS-SAPWMGPNYGV 360
Query: 348 QPPQGQAPPPVIPPPNQ-AGYGMASYQTQ 375
QPPQGQ + PNQ +GY +A Y+TQ
Sbjct: 361 QPPQGQNGSML---PNQPSGYRVAGYETQ 386
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 119 bits (298), Expect = 4e-27
Identities = 76/263 (28%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
++V NL + + + S G SC ++ + + Y FV F H A A+ MNG
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKDTSNHF----HVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ G++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 161 MLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V+ D +GKSKG+GFVSF DA+ A+ M G+ L G+QI A +K + T+
Sbjct: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKK--VERQTELK 277
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
T + +D + + N +Y + G+ D+ +R+ FSPFG I +V E KG+
Sbjct: 278 RTFEQMKQDRITRYQVVN--LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGF 335
Query: 243 SFVRFSTHESAAHAIVSVNGTTI 265
FV FS+ E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 114 bits (284), Expect = 2e-25
Identities = 86/268 (32%), Positives = 123/268 (45%), Gaps = 31/268 (11%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
+LYVG+L DVTE ++ + FS GP S + +IT +SN Y +V F +DA AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSN--YAYVNFQHTKDAEHAL 69
Query: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
MN I GK V++ W+ PS +K N +FV +L I + + + FG I
Sbjct: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFVKNLDKSINNKALYDTVSAFGNIL 126
Query: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
VV D SKGYGFV F AE AI M G L GR++ KS +
Sbjct: 127 SCNVVCD--ENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQF-------KSRK 177
Query: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
E E + + + VY + D+ ++ F FG + ++V +
Sbjct: 178 ER-------EAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKS 230
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEG 267
KG+ FV F HE A A+ +NG + G
Sbjct: 231 KGFGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 90.9 bits (224), Expect = 2e-18
Identities = 68/244 (27%), Positives = 111/244 (45%), Gaps = 23/244 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N D+ + + LF + GP S K++T+ + + FV F H DA A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 70 GRKILGKEVKVNWAT-----------TPSSQKKDTSNHFHV---FVGDLSPEITTEDIKS 115
G+++ GK++ V A T K+D + V +V +L I E ++
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRK 312
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
AF+PFG I+ A+V+ M G+SKG+GFV F + +A A+ M G+ + + + A R
Sbjct: 313 AFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
Query: 176 KPPAPK-STQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEI 234
K T E + V NQ +P + G + + + P QI +
Sbjct: 371 KEERQAYLTNEYMQRMASVRAVPNQRAPPS-----GYFMTAVPQTQNHAAYYPPSQIARL 425
Query: 235 RVFP 238
R P
Sbjct: 426 RPSP 429
Score = 88.6 bits (218), Expect = 8e-18
Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 27/189 (14%)
Query: 86 PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSF 145
PS+ T++ ++VGDL P++T + F+P G I R+ +D+ T S Y +V+F
Sbjct: 3 PSTPSYPTAS---LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNF 59
Query: 146 YNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNC 205
+ DAE+A+ M + G+ +R W+ R P KS N
Sbjct: 60 QHTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN------------------- 100
Query: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVN 261
++ + + ++ + T S FG I+ V + KGY FV F THE+A AI +N
Sbjct: 101 -IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMN 159
Query: 262 GTTIEGHVV 270
G + G V
Sbjct: 160 GMLLNGRKV 168
Score = 50.4 bits (119), Expect = 3e-06
Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 197 VNQSSPK--NCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFS 248
+N S+P ++Y G + +T+ ++ + FSP G I+ IR+ + Y++V F
Sbjct: 1 MNPSTPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQ 60
Query: 249 THESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
+ A HA+ ++N I+G V+ W + P + K+
Sbjct: 61 HTKDAEHALDTMNFDVIKGKPVRIMWSQRDPSLRKS 96
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 116 bits (290), Expect = 4e-26
Identities = 78/268 (29%), Positives = 131/268 (48%), Gaps = 25/268 (9%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
+LYVG+L DVTE L+ + FS +GP S ++ + + Y +V F + DA AL
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 68 MNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDAR 127
MN I GK +++ W+ + ++ S +VF+ +L I + + F+ FGKI ++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRR--SGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSK 128
Query: 128 VVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENN 187
V+ D SKGY FV F N+ A+ AI M G+ L G ++ + N
Sbjct: 129 VMSD--DQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVG------------RFKN 174
Query: 188 TKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE-----KGY 242
K E + + + VY + D+ ++ FS +G+ + ++V + KG+
Sbjct: 175 RKDREAE--LRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGF 232
Query: 243 SFVRFSTHESAAHAIVSVNGTTIEGHVV 270
FV F +HE+A A+ +NG I G ++
Sbjct: 233 GFVSFDSHEAAKKAVEEMNGRDINGQLI 260
Score = 102 bits (254), Expect = 6e-22
Identities = 70/260 (26%), Positives = 127/260 (48%), Gaps = 13/260 (5%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + + FS G S K++++ + Y FV F A A+ MNG
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
Query: 71 RKILGKEVKV----NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ + G +V V N + + S +V++ + ++ E +K F+ +GK
Sbjct: 160 KLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSV 219
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V+ D ++GKSKG+GFVSF + A+ A+ M G+ + G+ I A +K ++ +
Sbjct: 220 KVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVER-QAELKQ 277
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
+QL+ E + K +Y + + D+ +R FS FG I ++V E KG+
Sbjct: 278 MFEQLKRERIRGCQGVK---LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGF 334
Query: 243 SFVRFSTHESAAHAIVSVNG 262
+ FS+ E A A+ +NG
Sbjct: 335 GLICFSSPEDATKAMTEMNG 354
Score = 72.0 bits (175), Expect = 8e-13
Identities = 48/180 (26%), Positives = 86/180 (47%), Gaps = 17/180 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N D+ + + +FS+ G S K++T+ + + FV F H A A+ MN
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMN 251
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKS 115
GR I G+ + V A ++ + F +++ +L I E +++
Sbjct: 252 GRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRN 311
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
F+ FG IS +V+++ G+SKG+G + F + DA A+ M G+ LG + + A R
Sbjct: 312 EFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
Score = 38.1 bits (87), Expect = 0.013
Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
++Y G + + +T+ L+ + FS G ++ IR+ ++ GY++V F A A+ +
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 260 VNGTTIEGHVVKCYWGK 276
+N I+G ++ W +
Sbjct: 71 MNFDIIKGKSIRLMWSQ 87
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 115 bits (287), Expect = 8e-26
Identities = 74/263 (28%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ ++V V + ++ + +V++ + ++ E +K F FG
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V+ D +GKSKG+GFVSF DA+ A+ M G+ L G+QI A +K + T+
Sbjct: 221 KVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKK--VERQTELK 277
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
+ +D + + N +Y + G+ D+ +R+ FSPFG I +V E KG+
Sbjct: 278 RKFEQMKQDRITRYQGVN--LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGF 335
Query: 243 SFVRFSTHESAAHAIVSVNGTTI 265
FV FS+ E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 112 bits (280), Expect = 5e-25
Identities = 84/268 (31%), Positives = 123/268 (45%), Gaps = 31/268 (11%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
Query: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
MN I GK V++ W+ PS +K N +F+ +L I + + F+ FG I
Sbjct: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGN---IFIKNLDKSIDNKALYDTFSAFGNIL 126
Query: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
+VV D SKGYGFV F + AE AI M G L R++ KS +
Sbjct: 127 SCKVVCD--ENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVG-------RFKSRK 177
Query: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
E E + + + VY + D+ ++ F FG + ++V +
Sbjct: 178 ER-------EAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKS 230
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEG 267
KG+ FV F HE A A+ +NG + G
Sbjct: 231 KGFGFVSFERHEDAQKAVDEMNGKELNG 258
Score = 89.0 bits (219), Expect = 6e-18
Identities = 54/176 (30%), Positives = 82/176 (46%), Gaps = 24/176 (13%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
++VGDL P++T + F+P G I RV +DM T +S GY +V+F DAE A+ M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
+ G+ +R W+ R P KS N ++ + + +
Sbjct: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGN--------------------IFIKNLDKSIDN 112
Query: 219 QLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
+ + TFS FG I+ +V + KGY FV F T E+A AI +NG + V
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168
Score = 86.3 bits (212), Expect = 4e-17
Identities = 52/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N D+ + + LF + GP S K++T+ + + FV F H DA A+ MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
G+++ GK++ V A ++ + F +++V +L I E ++
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRK 312
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
F+PFG I+ A+V+ M G+SKG+GFV F + +A A+ M G+ + + + A R
Sbjct: 313 EFSPFGTITSAKVM--MEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQR 370
Query: 176 K 176
K
Sbjct: 371 K 371
Score = 48.5 bits (114), Expect = 1e-05
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 8/96 (8%)
Query: 197 VNQSSPKN--CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFS 248
+N S+P ++Y G + +T+ ++ + FSP G I+ IRV + GY++V F
Sbjct: 1 MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ 60
Query: 249 THESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
A A+ ++N I+G V+ W + P + K+
Sbjct: 61 QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKS 96
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 114 bits (284), Expect = 2e-25
Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ ++V V + ++ + +V++ + E+ E +K F+ FGK
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V++D GKSKG+GFVS+ DA A+ M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
+QL+ E + S + +Y + + D+ +R+ FSPFG I +V E KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 243 SFVRFSTHESAAHAIVSVNGTTI 265
FV FS+ E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 113 bits (283), Expect = 2e-25
Identities = 83/271 (30%), Positives = 126/271 (46%), Gaps = 31/271 (11%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
Query: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNIL 126
Query: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
+VV D SKGY FV F + A+ AI M G L R++ + R +
Sbjct: 127 SCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREA 181
Query: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
E K F + VY + D+ +++ FS FG+ + ++V +
Sbjct: 182 ELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKS 230
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
KG+ FV + HE A A+ +NG I G ++
Sbjct: 231 KGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.0 bits (206), Expect = 2e-16
Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N +V + + +LFSQ G S K++ + + FV + +H DA A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 176 K 176
K
Sbjct: 371 K 371
Score = 49.3 bits (116), Expect = 6e-06
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 200 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 253
SS ++Y G + S +T+ ++ + FSP G ++ IRV + GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 254 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
A+ ++N I+G ++ W + P + K+
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 114 bits (284), Expect = 2e-25
Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ ++V V + ++ + +V++ + E+ E +K F+ FGK
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V++D GKSKG+GFVS+ DA A+ M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
+QL+ E + S + +Y + + D+ +R+ FSPFG I +V E KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 243 SFVRFSTHESAAHAIVSVNGTTI 265
FV FS+ E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 113 bits (283), Expect = 2e-25
Identities = 83/271 (30%), Positives = 126/271 (46%), Gaps = 31/271 (11%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
Query: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNIL 126
Query: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
+VV D SKGY FV F + A+ AI M G L R++ + R +
Sbjct: 127 SCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREA 181
Query: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
E K F + VY + D+ +++ FS FG+ + ++V +
Sbjct: 182 ELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKS 230
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
KG+ FV + HE A A+ +NG I G ++
Sbjct: 231 KGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.0 bits (206), Expect = 2e-16
Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N +V + + +LFSQ G S K++ + + FV + +H DA A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 176 K 176
K
Sbjct: 371 K 371
Score = 49.3 bits (116), Expect = 6e-06
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 200 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 253
SS ++Y G + S +T+ ++ + FSP G ++ IRV + GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 254 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
A+ ++N I+G ++ W + P + K+
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 114 bits (284), Expect = 2e-25
Identities = 73/263 (27%), Positives = 127/263 (48%), Gaps = 13/263 (4%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + FS G SCK++ + + Y FV F A A+ MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKD----TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ ++V V + ++ + +V++ + E+ E +K F+ FGK
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V++D GKSKG+GFVS+ DA A+ M G+ + G+ I A +K ++ +
Sbjct: 221 KVMRD-PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVER-QAELKR 278
Query: 187 NTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KGY 242
+QL+ E + S + +Y + + D+ +R+ FSPFG I +V E KG+
Sbjct: 279 KFEQLKQERI---SRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGF 335
Query: 243 SFVRFSTHESAAHAIVSVNGTTI 265
FV FS+ E A A+ +NG +
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIV 358
Score = 113 bits (283), Expect = 2e-25
Identities = 83/271 (30%), Positives = 126/271 (46%), Gaps = 31/271 (11%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCK----MITEHTSNDPYCFVEFYEHRDAAAAL 65
+LYVG+L DVTE ++ + FS GP S + MIT + Y +V F + DA AL
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG--YAYVNFQQPADAERAL 69
Query: 66 AAMNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKIS 124
MN I GK +++ W+ PS +K N VF+ +L I + + F+ FG I
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGN---VFIKNLDKSIDNKALYDTFSAFGNIL 126
Query: 125 DARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQ 184
+VV D SKGY FV F + A+ AI M G L R++ + R +
Sbjct: 127 SCKVVCD--ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKEREA 181
Query: 185 ENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----- 239
E K F + VY + D+ +++ FS FG+ + ++V +
Sbjct: 182 ELGAKAKEFTN-----------VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKS 230
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
KG+ FV + HE A A+ +NG I G ++
Sbjct: 231 KGFGFVSYEKHEDANKAVEEMNGKEISGKII 261
Score = 84.0 bits (206), Expect = 2e-16
Identities = 51/181 (28%), Positives = 91/181 (50%), Gaps = 17/181 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
+Y+ N +V + + +LFSQ G S K++ + + FV + +H DA A+ MN
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHF--------------HVFVGDLSPEITTEDIKS 115
G++I GK + V A ++ + F ++++ +L I E ++
Sbjct: 253 GKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRK 312
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATR 175
F+PFG I+ A+V+ + G+SKG+GFV F + +A A+ M G+ +G + + A R
Sbjct: 313 EFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Query: 176 K 176
K
Sbjct: 371 K 371
Score = 49.3 bits (116), Expect = 6e-06
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 200 SSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESA 253
SS ++Y G + S +T+ ++ + FSP G ++ IRV + GY++V F A
Sbjct: 6 SSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADA 65
Query: 254 AHAIVSVNGTTIEGHVVKCYWGKESPDMTKN 284
A+ ++N I+G ++ W + P + K+
Sbjct: 66 ERALDTMNFDVIKGKPIRIMWSQRDPSLRKS 96
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 107 bits (268), Expect = 1e-23
Identities = 69/264 (26%), Positives = 128/264 (48%), Gaps = 14/264 (5%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + + LFS G SCK++ + + Y +V F A A+ MNG
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNG 167
Query: 71 RKILGKEVKVNWATTPSS-----QKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISD 125
++ ++V V P + +D + +VFV ++ +I E +K F +G
Sbjct: 168 VRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTES 227
Query: 126 ARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQE 185
+V++D A+GKSKG+GFV + A+ A++ + G+ + G+ + A +K +
Sbjct: 228 VKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIER-LAELR 285
Query: 186 NNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----KG 241
++LR ++ +S P +Y + + D+ +++ FS FG I +V E KG
Sbjct: 286 RRFERLRLKE---KSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKG 342
Query: 242 YSFVRFSTHESAAHAIVSVNGTTI 265
+ V FS+ E A A+ +NG +
Sbjct: 343 FGVVCFSSFEEATKAVDEMNGRIV 366
Score = 104 bits (260), Expect = 1e-22
Identities = 76/267 (28%), Positives = 125/267 (46%), Gaps = 24/267 (8%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
LYVG+L DVTE ++ + F GP + ++ + + P Y +V F DA AL M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128
N I GK ++ W+ +K S ++F+ +L I + F+ FG I +V
Sbjct: 80 NFDLINGKPFRLMWSQPDDRLRK--SGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKV 137
Query: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNT 188
V D SKGY +V F + A AI HM G L RQ+ K P ++ +
Sbjct: 138 VCD--DNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVG--RFKFPEERAAEVRTR 193
Query: 189 KQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE-----KGYS 243
+ F +V + I + D+ +++ F +G ++V + KG+
Sbjct: 194 DRATFTNV-----------FVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFG 242
Query: 244 FVRFSTHESAAHAIVSVNGTTIEGHVV 270
FVR+ THE+A A++ ++G +I+G V+
Sbjct: 243 FVRYETHEAAQKAVLDLHGKSIDGKVL 269
Score = 68.6 bits (166), Expect = 9e-12
Identities = 45/173 (26%), Positives = 83/173 (47%), Gaps = 17/173 (9%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP-YCFVEFYEHRDAAAALAAMN 69
++V N+ D+ + + +LF + GP +S K+I + + + FV + H A A+ ++
Sbjct: 201 VFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLH 260
Query: 70 GRKILGKEVKVNWATTPSSQKKDTSNHFH--------------VFVGDLSPEITTEDIKS 115
G+ I GK + V A + + F +++ +L I E +K
Sbjct: 261 GKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKE 320
Query: 116 AFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI 168
F+ FG IS A+V+ M G+ KG+G V F + +A A+ M G+ +G + +
Sbjct: 321 EFSSFGSISRAKVM--MEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPL 371
Score = 30.8 bits (68), Expect = 2.1
Identities = 18/84 (21%), Positives = 36/84 (42%), Gaps = 6/84 (7%)
Query: 207 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSV 260
+Y G + +T+ ++ + F P G + R+ + GY +V F A A+ ++
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 261 NGTTIEGHVVKCYWGKESPDMTKN 284
N I G + W + + K+
Sbjct: 80 NFDLINGKPFRLMWSQPDDRLRKS 103
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 107 bits (267), Expect = 2e-23
Identities = 92/374 (24%), Positives = 163/374 (43%), Gaps = 38/374 (10%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNG 70
+++ NL + + FS G SCK+ + + + FV F H A A+ MNG
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
Query: 71 RKILGKEVKVNWATTPSSQKKDTS----NHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+ ++V V + ++ + +++V +L ++ + ++ F+ FGK+
Sbjct: 161 MLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSV 220
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQEN 186
+V++D +G S+ +GFV+F +A+ A+VHM G+ + GR + +A R A K +
Sbjct: 221 KVMRD-NSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLL---YAGR---AQKRVERQ 273
Query: 187 NTKQLRFEDVVNQSSPK--NCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE----K 240
N + RFE + + +Y + + D +R+ FSP+G I +V E K
Sbjct: 274 NELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSK 333
Query: 241 GYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPD----MTKNFQQVDYSQWGQW 296
G+ FV FS+ E A A+ +NG + + + + +T + Q +
Sbjct: 334 GFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLS 393
Query: 297 SQVYGNPQQYGQYMANGWQVPP--YGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQ--- 351
+ + G+ QQ Y PP YG G P+ W +QPP+
Sbjct: 394 NPLLGSFQQPSSYFLPAMPQPPAQAAYYG-----CGPVTPTQPAPRWT----SQPPRPSC 444
Query: 352 -GQAPPPVIP--PP 362
PPV+P PP
Sbjct: 445 ASMVRPPVVPRRPP 458
Score = 100 bits (249), Expect = 2e-21
Identities = 71/270 (26%), Positives = 127/270 (47%), Gaps = 29/270 (10%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
+LYVG+L DVTE ++ + FS GP S ++ + + Y ++ F + DA AL
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 68 MNGRKILGKEVKVNWA-TTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
MN + G+ +++ W+ P +K N +F+ +L I + + F+ FG I
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGN---IFIKNLEDSIDNKALYDTFSTFGNILSC 128
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRT-NWATRKPPAPKSTQE 185
+V D S+G+GFV F A+ AI M G L R++ ++ +R+ + E
Sbjct: 129 KVACD--EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRR----EREAE 182
Query: 186 NNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKG---- 241
+ L F + +Y + + +Q ++ FS FG+++ ++V +
Sbjct: 183 LGARALEFTN-----------IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSR 231
Query: 242 -YSFVRFSTHESAAHAIVSVNGTTIEGHVV 270
+ FV F HE A A+V +NG + G ++
Sbjct: 232 CFGFVNFEKHEEAQKAVVHMNGKEVSGRLL 261
Score = 45.1 bits (105), Expect = 1e-04
Identities = 21/85 (24%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
++Y G + +T+ ++ + FSP G I+ IRV + GY+++ F A A+ +
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 260 VNGTTIEGHVVKCYWGKESPDMTKN 284
+N ++G ++ W + P + K+
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKS 96
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 105 bits (261), Expect = 9e-23
Identities = 76/315 (24%), Positives = 147/315 (46%), Gaps = 61/315 (19%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
L V L +++T+ + LF IG +SCK++ + + Y FV + + +DA A+ +
Sbjct: 41 LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
Query: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128
NG ++ K +KV++A S+ +D + ++V L +T ++++ F+ +G+I +R+
Sbjct: 101 NGLRLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMTQKELEQLFSQYGRIITSRI 156
Query: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQ------------WLGGRQIRTNWA--- 173
+ D TG S+G GF+ F +++AE AI + GQ + +TN A
Sbjct: 157 LVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILS 216
Query: 174 ------TRKPPAPKSTQENNTKQLRFEDVVNQS------SPKNC---------------- 205
R+ P P + Q ++ R ++++N + SP
Sbjct: 217 QLYQSPNRRYPGPLAQQ---AQRFRLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPG 273
Query: 206 ---TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHA 256
++ +A + ++ Q F PFG + ++V + KG+ FV + ++ AA A
Sbjct: 274 TGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMA 333
Query: 257 IVSVNGTTIEGHVVK 271
I S+NG + V++
Sbjct: 334 IASLNGYRLGDRVLQ 348
Score = 77.4 bits (189), Expect = 2e-14
Identities = 50/188 (26%), Positives = 89/188 (47%), Gaps = 28/188 (14%)
Query: 81 NWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGY 140
N ++P + ++ V L +T E++KS F G+I ++V+D TG+S GY
Sbjct: 23 NNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGY 82
Query: 141 GFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQS 200
GFV++ + DAE AI + G L + I+ ++A +P + +
Sbjct: 83 GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA--RP--------------------SSA 120
Query: 201 SPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAA 254
S ++ +Y G+ +T + + Q FS +G+I+ R+ + +G F+RF A
Sbjct: 121 SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAE 180
Query: 255 HAIVSVNG 262
AI +NG
Sbjct: 181 EAIKGLNG 188
Score = 58.2 bits (139), Expect = 1e-08
Identities = 27/78 (34%), Positives = 46/78 (58%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
+FV +L+P+ + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 159 GGQWLGGRQIRTNWATRK 176
G LG R ++ ++ T K
Sbjct: 338 NGYRLGDRVLQVSFKTNK 355
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/84 (28%), Positives = 47/84 (55%), Gaps = 5/84 (5%)
Query: 6 GQPRT---LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRD 60
G P T ++V NL+ D E ++ Q+F G + K+I + +N + FV + +
Sbjct: 270 GHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDE 329
Query: 61 AAAALAAMNGRKILGKEVKVNWAT 84
AA A+A++NG ++ + ++V++ T
Sbjct: 330 AAMAIASLNGYRLGDRVLQVSFKT 353
Score = 30.8 bits (68), Expect = 2.1
Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + ++ F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 46 LPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 105
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 106 QTKTIKVSYARPS 118
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 104 bits (259), Expect = 1e-22
Identities = 74/318 (23%), Positives = 144/318 (45%), Gaps = 55/318 (17%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 45 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 104
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 105 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 160
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 161 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 220
Query: 183 TQ------------------ENNTKQLRFEDVVNQS------SP---------------- 202
+Q + ++ R ++++N + SP
Sbjct: 221 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 280
Query: 203 ---KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESA 253
++ ++ + ++ Q F PFG + ++V + KG+ FV + ++ A
Sbjct: 281 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 340
Query: 254 AHAIVSVNGTTIEGHVVK 271
A AI S+NG + V++
Sbjct: 341 AMAIASLNGYRLGDRVLQ 358
Score = 59.3 bits (142), Expect = 5e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 282 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 341
Query: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
AI + G LG R ++ ++ T K
Sbjct: 342 MAIASLNGYRLGDRVLQVSFKTNK 365
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 69 NGRKILGKEVKVNWAT 84
NG ++ + ++V++ T
Sbjct: 348 NGYRLGDRVLQVSFKT 363
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 56 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 115
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 116 QTKTIKVSYARPS 128
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 104 bits (259), Expect = 1e-22
Identities = 74/318 (23%), Positives = 144/318 (45%), Gaps = 55/318 (17%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 183 TQ------------------ENNTKQLRFEDVVNQS------SP---------------- 202
+Q + ++ R ++++N + SP
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 203 ---KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESA 253
++ ++ + ++ Q F PFG + ++V + KG+ FV + ++ A
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 254 AHAIVSVNGTTIEGHVVK 271
A AI S+NG + V++
Sbjct: 338 AMAIASLNGYRLGDRVLQ 355
Score = 59.3 bits (142), Expect = 5e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
AI + G LG R ++ ++ T K
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNK 362
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 69 NGRKILGKEVKVNWAT 84
NG ++ + ++V++ T
Sbjct: 345 NGYRLGDRVLQVSFKT 360
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 53 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 112
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 113 QTKTIKVSYARPS 125
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 104 bits (259), Expect = 1e-22
Identities = 74/318 (23%), Positives = 144/318 (45%), Gaps = 55/318 (17%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 59 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 118
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 119 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 174
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 175 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 234
Query: 183 TQ------------------ENNTKQLRFEDVVNQS------SP---------------- 202
+Q + ++ R ++++N + SP
Sbjct: 235 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 294
Query: 203 ---KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESA 253
++ ++ + ++ Q F PFG + ++V + KG+ FV + ++ A
Sbjct: 295 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 354
Query: 254 AHAIVSVNGTTIEGHVVK 271
A AI S+NG + V++
Sbjct: 355 AMAIASLNGYRLGDRVLQ 372
Score = 59.3 bits (142), Expect = 5e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 296 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 355
Query: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
AI + G LG R ++ ++ T K
Sbjct: 356 MAIASLNGYRLGDRVLQVSFKTNK 379
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 69 NGRKILGKEVKVNWAT 84
NG ++ + ++V++ T
Sbjct: 362 NGYRLGDRVLQVSFKT 377
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 70 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 129
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 130 QTKTIKVSYARPS 142
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 104 bits (259), Expect = 1e-22
Identities = 74/318 (23%), Positives = 144/318 (45%), Gaps = 55/318 (17%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 183 TQ------------------ENNTKQLRFEDVVNQS------SP---------------- 202
+Q + ++ R ++++N + SP
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPG 277
Query: 203 ---KNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESA 253
++ ++ + ++ Q F PFG + ++V + KG+ FV + ++ A
Sbjct: 278 HTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEA 337
Query: 254 AHAIVSVNGTTIEGHVVK 271
A AI S+NG + V++
Sbjct: 338 AMAIASLNGYRLGDRVLQ 355
Score = 59.3 bits (142), Expect = 5e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 279 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 338
Query: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
AI + G LG R ++ ++ T K
Sbjct: 339 MAIASLNGYRLGDRVLQVSFKTNK 362
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 69 NGRKILGKEVKVNWAT 84
NG ++ + ++V++ T
Sbjct: 345 NGYRLGDRVLQVSFKT 360
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 53 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 112
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 113 QTKTIKVSYARPS 125
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 100 bits (250), Expect = 2e-21
Identities = 74/332 (22%), Positives = 144/332 (43%), Gaps = 69/332 (20%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
Query: 183 TQ------------------ENNTKQLRFEDVVNQS-----------SPKNC-------- 205
+Q + ++ R ++++N + P C
Sbjct: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPIT 277
Query: 206 --------------------TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------ 239
++ ++ + ++ Q F PFG + ++V +
Sbjct: 278 IDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKC 337
Query: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
KG+ FV + ++ AA AI S+NG + V++
Sbjct: 338 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
Score = 59.3 bits (142), Expect = 5e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 293 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 352
Query: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
AI + G LG R ++ ++ T K
Sbjct: 353 MAIASLNGYRLGDRVLQVSFKTNK 376
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 69 NGRKILGKEVKVNWAT 84
NG ++ + ++V++ T
Sbjct: 359 NGYRLGDRVLQVSFKT 374
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 53 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 112
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 113 QTKTIKVSYARPS 125
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 100 bits (248), Expect = 3e-21
Identities = 62/178 (34%), Positives = 98/178 (55%), Gaps = 6/178 (3%)
Query: 2 MEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHR 59
+ + Q T+YVG L V+E L+ +LF Q GP + M + + + Y FVEF
Sbjct: 6 ISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEE 65
Query: 60 DAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAP 119
DA A+ MN K+ GK ++VN A S+ K+ ++F+G+L PEI + + F+
Sbjct: 66 DADYAIKIMNMIKLYGKPIRVNKA---SAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSA 122
Query: 120 FGKISDA-RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRK 176
FG I ++++D TG SKGY F++F + ++ AI M GQ+L R I ++A +K
Sbjct: 123 FGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKK 180
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/187 (26%), Positives = 89/187 (47%), Gaps = 31/187 (16%)
Query: 83 ATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGF 142
A P S++ + V+VG L +++ + F G + + + KD TG+ +GYGF
Sbjct: 2 AAGPISERNQDAT---VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGF 58
Query: 143 VSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSP 202
V F ++ DA+ AI M L G+ IR N A+ N++
Sbjct: 59 VEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAH---------------------NKNLD 97
Query: 203 KNCTVYCGGIASGLTDQLMRQTFSPFGQIME---IRVFPE----KGYSFVRFSTHESAAH 255
++ G + + ++L+ TFS FG I++ I P+ KGY+F+ F++ +++
Sbjct: 98 VGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDA 157
Query: 256 AIVSVNG 262
AI ++NG
Sbjct: 158 AIEAMNG 164
Score = 38.9 bits (89), Expect = 0.008
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 8/91 (8%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEH--TSNDP-YCFVEFYEHRDAAAALAA 67
+++GNL ++ E L+ FS G I T N Y F+ F + AA+ A
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
Query: 68 MNGRKILGKEVKVNWATTPSSQKKDTSNHFH 98
MNG+ + + + V++A KKD+ H
Sbjct: 162 MNGQYLCNRPITVSYAF-----KKDSKGERH 187
Score = 28.9 bits (63), Expect = 7.9
Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 312 NGWQVPPYGVYGQPWN---QQGFGVDQSPSAAWMGGFGAQPPQGQA-PPPVIPPPNQAG 366
+G Q PP G P G P + MG G PP G PPP++PP G
Sbjct: 329 SGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTG 387
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 100 bits (248), Expect = 3e-21
Identities = 77/319 (24%), Positives = 143/319 (44%), Gaps = 56/319 (17%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + DA
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG K+ K +KV++A S+ +D + ++V L ++ ++++ F+ +G+
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ K+
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 183 TQ------------------ENNTKQLRFEDVVNQS------SPKNCTVYCGGIASGLT- 217
Q + T++ R ++++N + SP G GL+
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSG 270
Query: 218 -------------------DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHES 252
+ ++ Q F PFG + ++V + KG+ FV + ++
Sbjct: 271 GAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDE 330
Query: 253 AAHAIVSVNGTTIEGHVVK 271
AA AI S+NG + V++
Sbjct: 331 AAMAIASLNGYRLGERVLQ 349
Score = 60.5 bits (145), Expect = 2e-09
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
+FV +LSPE + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 159 GGQWLGGRQIRTNWATRK 176
G LG R ++ ++ T K
Sbjct: 339 NGYRLGERVLQVSFKTSK 356
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/77 (29%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS + E ++ QLF G + K+I + T+N + FV + +AA A+A++
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 69 NGRKILGKEVKVNWATT 85
NG ++ + ++V++ T+
Sbjct: 339 NGYRLGERVLQVSFKTS 355
Score = 30.0 bits (66), Expect = 3.5
Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + F G I ++ +K GY FV +S A AI ++NG +
Sbjct: 46 LPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKL 105
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 106 QTKTIKVSYARPS 118
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 99.0 bits (245), Expect = 6e-21
Identities = 79/326 (24%), Positives = 145/326 (44%), Gaps = 63/326 (19%)
Query: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
D L V L +++T+ LF IG +SCK++ + + Y FV + + DA
Sbjct: 35 DDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDAD 94
Query: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
A+ +NG K+ K +KV++A S+ +D + ++V L ++ ++++ F+ +G+
Sbjct: 95 KAINTLNGLKLQTKTIKVSYARPSSASIRDAN----LYVSGLPKTMSQKEMEQLFSQYGR 150
Query: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ K+
Sbjct: 151 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKT 210
Query: 183 TQ------------------ENNTKQLRFEDVVNQS----SPKNCTVYCGGIA----SGL 216
Q + T++ R ++++N + SP + IA SGL
Sbjct: 211 GQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGL 270
Query: 217 T-------------------------DQLMRQTFSPFGQIMEIRVFPE------KGYSFV 245
+ ++ Q F PFG + ++V + KG+ FV
Sbjct: 271 AGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFV 330
Query: 246 RFSTHESAAHAIVSVNGTTIEGHVVK 271
+ ++ AA AI S+NG + V++
Sbjct: 331 TMTNYDEAAMAIASLNGYRLGERVLQ 356
Score = 60.5 bits (145), Expect = 2e-09
Identities = 29/78 (37%), Positives = 46/78 (58%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
+FV +LSPE + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 159 GGQWLGGRQIRTNWATRK 176
G LG R ++ ++ T K
Sbjct: 346 NGYRLGERVLQVSFKTSK 363
Score = 41.6 bits (96), Expect = 0.001
Identities = 23/77 (29%), Positives = 46/77 (59%), Gaps = 2/77 (2%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
++V NLS + E ++ QLF G + K+I + T+N + FV + +AA A+A++
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 69 NGRKILGKEVKVNWATT 85
NG ++ + ++V++ T+
Sbjct: 346 NGYRLGERVLQVSFKTS 362
Score = 30.0 bits (66), Expect = 3.5
Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
+ +T + F G I ++ +K GY FV +S A AI ++NG +
Sbjct: 46 LPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKL 105
Query: 266 EGHVVKCYWGKES 278
+ +K + + S
Sbjct: 106 QTKTIKVSYARPS 118
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 97.4 bits (241), Expect = 2e-20
Identities = 74/290 (25%), Positives = 131/290 (45%), Gaps = 42/290 (14%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAAM 68
L V L +++T+ + LFS IG +S K+I + + Y FV + +DA A+ +
Sbjct: 22 LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81
Query: 69 NGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARV 128
NG ++ K +KV++A S KD ++++ L +T +D++ F+ FG+I ++RV
Sbjct: 82 NGLRLQSKTIKVSYARPSSEVIKDA----NLYISGLPRTMTQKDVEDMFSRFGRIINSRV 137
Query: 129 VKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGG--RQIRTNWATR----------- 175
+ D TG S+G F+ F + +AE AI G G I +A
Sbjct: 138 LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLS 197
Query: 176 ---KPPAPK--STQENNTKQLRFEDV------------VNQSSPKNCTVYCGGIASGLTD 218
PA + + ++ RF + V ++ ++ + +
Sbjct: 198 QLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADE 257
Query: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNG 262
++ Q F PFG + ++V + KG+ FV + +E AA AI S+NG
Sbjct: 258 GILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNG 307
Score = 75.1 bits (183), Expect = 1e-13
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 48/258 (18%)
Query: 98 HVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVH 157
++ V L +T ++++S F+ G++ A++++D G S GYGFV++ DAE AI
Sbjct: 21 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 80
Query: 158 MGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLT 217
+ G L + I+ ++A P S +V+ K+ +Y G+ +T
Sbjct: 81 LNGLRLQSKTIKVSYA-----RPSS------------EVI-----KDANLYISGLPRTMT 118
Query: 218 DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGH--- 268
+ + FS FG+I+ RV + +G +F+RF A AI S NG G
Sbjct: 119 QKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEP 178
Query: 269 -VVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNP-QQYG---QYMANGWQVPPYGVYG 323
VK +P+ KN + SQ+Y +P +++G + A ++ P GV
Sbjct: 179 ITVKF---AANPNQNKNVALL--------SQLYHSPARRFGGPVHHQAQRFRFSPMGV-D 226
Query: 324 QPWNQQGFGVDQSPSAAW 341
G V + S+ W
Sbjct: 227 HMSGLSGVNVPGNASSGW 244
Score = 63.2 bits (152), Expect = 4e-10
Identities = 46/216 (21%), Positives = 90/216 (41%), Gaps = 50/216 (23%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
LY+ L R +T+ + +FS+ G + +++ + T+ + F+ F + +A A+ +
Sbjct: 108 LYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSF 167
Query: 69 NGRKILGKE--VKVNWATTPSSQKK----------------------------------- 91
NG K G + V +A P+ K
Sbjct: 168 NGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDH 227
Query: 92 -----------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGY 140
+ S+ + +F+ +L + + F PFG +++ +V++D T K KG+
Sbjct: 228 MSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGF 287
Query: 141 GFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRK 176
GFV+ N +A AI + G LG + ++ ++ T K
Sbjct: 288 GFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK 323
>gi|25470890 DAZ associated protein 1 isoform a [Homo sapiens]
Length = 378
Score = 92.8 bits (229), Expect = 4e-19
Identities = 75/271 (27%), Positives = 123/271 (45%), Gaps = 28/271 (10%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
+FVG L T E ++S F+ +G++ D ++KD T +S+G+GFV F + + ++
Sbjct: 12 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDP-NCVGTVLAS 70
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLR-FEDVVNQSSPKNCTVYCGGIASGLT 217
L GR I KP P+ Q T+ ++ + K+ ++ GGI
Sbjct: 71 RPHTLDGRNI-----DPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCG 125
Query: 218 DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
+ +R+ F FG + E+ + + +G+ F+ F +S A V+++ I G V+
Sbjct: 126 ETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQA-VNMHFHDIMGKKVE 184
Query: 272 CYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGF 331
+ ++ Q SQWG S+V N ANGW P + Q + QG
Sbjct: 185 VKRAEPRDSKSQAPGQPGASQWG--SRVVPN-------AANGWAGQPPPTWQQGYGPQGM 235
Query: 332 GVDQSPSAAWMGGFGAQPPQGQAPPPVIPPP 362
V P+ +GG+G P APPP PPP
Sbjct: 236 WV---PAGQAIGGYGPPPAGRGAPPP--PPP 261
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA- 67
L+VG L T+ + FSQ G C ++ + T+N + FV+F + LA+
Sbjct: 12 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASR 71
Query: 68 ---MNGRKILGKEV------------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTED 112
++GR I K K W P S D S +FVG + +
Sbjct: 72 PHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRS---DNSKSNKIFVGGIPHNCGETE 128
Query: 113 IKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAI 155
++ F FG +++ ++ D + +G+GF++F ++ + A+
Sbjct: 129 LREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAV 171
>gi|25470886 DAZ associated protein 1 isoform b [Homo sapiens]
Length = 407
Score = 92.8 bits (229), Expect = 4e-19
Identities = 75/271 (27%), Positives = 123/271 (45%), Gaps = 28/271 (10%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
+FVG L T E ++S F+ +G++ D ++KD T +S+G+GFV F + + ++
Sbjct: 12 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDP-NCVGTVLAS 70
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLR-FEDVVNQSSPKNCTVYCGGIASGLT 217
L GR I KP P+ Q T+ ++ + K+ ++ GGI
Sbjct: 71 RPHTLDGRNI-----DPKPCTPRGMQPERTRPKEGWQKGPRSDNSKSNKIFVGGIPHNCG 125
Query: 218 DQLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
+ +R+ F FG + E+ + + +G+ F+ F +S A V+++ I G V+
Sbjct: 126 ETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQA-VNMHFHDIMGKKVE 184
Query: 272 CYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGF 331
+ ++ Q SQWG S+V N ANGW P + Q + QG
Sbjct: 185 VKRAEPRDSKSQAPGQPGASQWG--SRVVPN-------AANGWAGQPPPTWQQGYGPQGM 235
Query: 332 GVDQSPSAAWMGGFGAQPPQGQAPPPVIPPP 362
V P+ +GG+G P APPP PPP
Sbjct: 236 WV---PAGQAIGGYGPPPAGRGAPPP--PPP 261
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/163 (23%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA- 67
L+VG L T+ + FSQ G C ++ + T+N + FV+F + LA+
Sbjct: 12 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKDPNCVGTVLASR 71
Query: 68 ---MNGRKILGKEV------------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTED 112
++GR I K K W P S D S +FVG + +
Sbjct: 72 PHTLDGRNIDPKPCTPRGMQPERTRPKEGWQKGPRS---DNSKSNKIFVGGIPHNCGETE 128
Query: 113 IKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAI 155
++ F FG +++ ++ D + +G+GF++F ++ + A+
Sbjct: 129 LREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAV 171
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 83.2 bits (204), Expect = 4e-16
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
+YVG++ ++ E I Q F+ GP KS M + + + + FVE+ A AL M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 69 NGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFG 121
N + G+ +KV A Q + + F+ ++V + +++ +DIKS F FG
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 207
Query: 122 KISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPK 181
KI + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 208 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 266
Query: 182 ST 183
T
Sbjct: 267 LT 268
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A+ M
Sbjct: 88 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 147
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
LGGR I+ + A Q + + ++ N +Y + L+D
Sbjct: 148 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 196
Query: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
++ F FG+I + + KGY F+ + +S+ A+ S+N + G ++
Sbjct: 197 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 255
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 205 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 258
C VY G I L + +RQ F+PFG I I + KG++FV + E+A A+
Sbjct: 86 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 145
Query: 259 SVNGTTIEGHVVK 271
+N + G +K
Sbjct: 146 QMNSVMLGGRNIK 158
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 83.2 bits (204), Expect = 4e-16
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
+YVG++ ++ E I Q F+ GP KS M + + + + FVE+ A AL M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 69 NGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFG 121
N + G+ +KV A Q + + F+ ++V + +++ +DIKS F FG
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
Query: 122 KISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPK 181
KI + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 292
Query: 182 ST 183
T
Sbjct: 293 LT 294
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A+ M
Sbjct: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
LGGR I+ + A Q + + ++ N +Y + L+D
Sbjct: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
Query: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
++ F FG+I + + KGY F+ + +S+ A+ S+N + G ++
Sbjct: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 205 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 258
C VY G I L + +RQ F+PFG I I + KG++FV + E+A A+
Sbjct: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
Query: 259 SVNGTTIEGHVVK 271
+N + G +K
Sbjct: 172 QMNSVMLGGRNIK 184
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 83.2 bits (204), Expect = 4e-16
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
+YVG++ ++ E I Q F+ GP KS M + + + + FVE+ A AL M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 69 NGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFG 121
N + G+ +KV A Q + + F+ ++V + +++ +DIKS F FG
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
Query: 122 KISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPK 181
KI + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 251 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 309
Query: 182 ST 183
T
Sbjct: 310 LT 311
Score = 63.5 bits (153), Expect = 3e-10
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A+ M
Sbjct: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
LGGR I+ + A Q + + ++ N +Y + L+D
Sbjct: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
Query: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
++ F FG+I + + KGY F+ + +S+ A+ S+N + G ++
Sbjct: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 205 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 258
C VY G I L + +RQ F+PFG I I + KG++FV + E+A A+
Sbjct: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
Query: 259 SVNGTTIEGHVVK 271
+N + G +K
Sbjct: 189 QMNSVMLGGRNIK 201
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 24/168 (14%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ +DA+ A+ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
+ GR +R W+ R P KS N V+ + + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 219 QLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNG 262
+ + FS FG I+ +V + KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 79.7 bits (195), Expect = 4e-15
Identities = 54/162 (33%), Positives = 83/162 (51%), Gaps = 8/162 (4%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
+LYVG+L +VTE ++ + FS GP S ++ + + Y +V + + DA AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 68 MNGRKILGKEVKVNWATT-PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+N I G+ V++ W+ PS +K N VF+ +L I + + + F+ FG I
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGN---VFIKNLGKTIDNKALYNIFSAFGNILSC 119
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI 168
+V D KGYGFV F + AE AI M G +L R+I
Sbjct: 120 KVACDEKG--PKGYGFVHFQKQESAERAIDVMNGMFLNYRKI 159
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/85 (27%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
++Y G + +T+ ++ + FSP G I+ IR+ +K GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 260 VNGTTIEGHVVKCYWGKESPDMTKN 284
+N I+G V+ W + P + K+
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKS 87
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/168 (29%), Positives = 78/168 (46%), Gaps = 24/168 (14%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
++VGDL PE+T + F+P G I R+ +D T +S GY +V++ +DA+ A+ +
Sbjct: 4 LYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETL 63
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
+ GR +R W+ R P KS N V+ + + +
Sbjct: 64 NFDVIKGRPVRIMWSQRDPSLRKSGVGN--------------------VFIKNLGKTIDN 103
Query: 219 QLMRQTFSPFGQIMEIRVFPE----KGYSFVRFSTHESAAHAIVSVNG 262
+ + FS FG I+ +V + KGY FV F ESA AI +NG
Sbjct: 104 KALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNG 151
Score = 79.7 bits (195), Expect = 4e-15
Identities = 54/162 (33%), Positives = 83/162 (51%), Gaps = 8/162 (4%)
Query: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAAAALAA 67
+LYVG+L +VTE ++ + FS GP S ++ + + Y +V + + DA AL
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 68 MNGRKILGKEVKVNWATT-PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDA 126
+N I G+ V++ W+ PS +K N VF+ +L I + + + F+ FG I
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGN---VFIKNLGKTIDNKALYNIFSAFGNILSC 119
Query: 127 RVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQI 168
+V D KGYGFV F + AE AI M G +L R+I
Sbjct: 120 KVACDEKG--PKGYGFVHFQKQESAERAIDVMNGMFLNYRKI 159
Score = 48.1 bits (113), Expect = 1e-05
Identities = 23/85 (27%), Positives = 45/85 (52%), Gaps = 6/85 (7%)
Query: 206 TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVS 259
++Y G + +T+ ++ + FSP G I+ IR+ +K GY++V + A A+ +
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 260 VNGTTIEGHVVKCYWGKESPDMTKN 284
+N I+G V+ W + P + K+
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKS 87
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 77.8 bits (190), Expect = 1e-14
Identities = 48/198 (24%), Positives = 99/198 (50%), Gaps = 11/198 (5%)
Query: 4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDA 61
++ RT++ L+ + + + FS +G + +MI++ S + +VEF +
Sbjct: 148 EERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSV 207
Query: 62 AAALAAMNGRKILGKEV--------KVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDI 113
A+ + G+++LG + K A ++ +K ++ ++VG L IT + +
Sbjct: 208 PLAIG-LTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDML 266
Query: 114 KSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWA 173
+ F PFG+I +++ D TG+SKGYGF++F + A+ A+ + G L GR ++
Sbjct: 267 RGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHV 326
Query: 174 TRKPPAPKSTQENNTKQL 191
T + A ++ ++ +L
Sbjct: 327 TERTDASSASSFLDSDEL 344
Score = 72.4 bits (176), Expect = 6e-13
Identities = 58/231 (25%), Positives = 98/231 (42%), Gaps = 23/231 (9%)
Query: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
VF L+ I D++ F+ GK+ D R++ D + +SKG +V F + AI
Sbjct: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLT 214
Query: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
G + LG P +++Q + + + + S +Y G + +T+
Sbjct: 215 GQRVLG-----------VPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITE 263
Query: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKC 272
++R F PFG+I I++ + KGY F+ FS E A A+ +NG + G +K
Sbjct: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
Query: 273 YWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMA-----NGWQVPP 318
E D + +D + + G + Q MA G Q+PP
Sbjct: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRL-QLMARLAEGTGLQIPP 373
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,605,643
Number of Sequences: 37866
Number of extensions: 820130
Number of successful extensions: 5895
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 258
Number of HSP's successfully gapped in prelim test: 111
Number of HSP's that attempted gapping in prelim test: 4248
Number of HSP's gapped (non-prelim): 1131
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.