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Search of human proteins with 4507163
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 941 0.0
gi|4507161 SRY-box 11 [Homo sapiens] 291 1e-78
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 189 4e-48
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 144 1e-34
gi|5902108 SRY-box 21 [Homo sapiens] 139 6e-33
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 129 4e-30
gi|5902106 SRY-box 15 [Homo sapiens] 128 1e-29
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 128 1e-29
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 121 1e-27
gi|4759162 SRY-box 14 [Homo sapiens] 121 1e-27
gi|13899269 SRY-box 7 [Homo sapiens] 119 6e-27
gi|4557853 transcription factor SOX9 [Homo sapiens] 119 6e-27
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 119 6e-27
gi|11967991 SRY-box 17 [Homo sapiens] 114 3e-25
gi|8924248 SRY-box 18 [Homo sapiens] 110 2e-24
gi|41406089 SRY-box 13 [Homo sapiens] 104 2e-22
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 103 3e-22
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 103 3e-22
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 103 3e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 103 3e-22
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 102 6e-22
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 102 6e-22
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 102 6e-22
gi|4507225 sex determining region Y [Homo sapiens] 100 4e-21
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 85 2e-16
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 85 2e-16
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 85 2e-16
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 85 2e-16
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 85 2e-16
gi|109255251 loricrin [Homo sapiens] 80 4e-15
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 941 bits (2431), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60
MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
Sbjct: 1 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60
Query: 61 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120
RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
Sbjct: 61 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120
Query: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180
ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
Sbjct: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180
Query: 181 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE 240
GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE
Sbjct: 181 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE 240
Query: 241 QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG 300
QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG
Sbjct: 241 QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG 300
Query: 301 GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG 360
GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG
Sbjct: 301 GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG 360
Query: 361 YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG 420
YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG
Sbjct: 361 YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG 420
Query: 421 SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY 474
SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
Sbjct: 421 SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY 474
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 291 bits (744), Expect = 1e-78
Identities = 209/491 (42%), Positives = 258/491 (52%), Gaps = 67/491 (13%)
Query: 1 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60
MVQQ + E E+ L E+ D+ G + A SP + DP WCKT SGHIK
Sbjct: 1 MVQQAESLE-AESNLPREALDTEEGEFM--ACSPVALDES-------DPDWCKTASGHIK 50
Query: 61 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120
RPMNAFMVWS+IERRKIMEQSPDMHNAEISKRLGKRWK+LKDS+KIPFIREAERLRLKHM
Sbjct: 51 RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM 110
Query: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180
ADYPDYKYRPRKK K + S+ +AS P +K GGGG GGG GG+ + G
Sbjct: 111 ADYPDYKYRPRKKPKM---DPSAKPSASQSP----EKSAAGGGGGSAGGGAGGAKTSKGS 163
Query: 181 ----GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAAS 236
G + A +K K+ S GGAG ++ +GGGG GK
Sbjct: 164 SKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCV--- 220
Query: 237 FAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV 296
F E D + + L PG+ ++ R
Sbjct: 221 FLDED---------DDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQ--PSQLLRR 269
Query: 297 YLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPA 356
Y + S + + + A+ + LY+E AG A+S A G S
Sbjct: 270 YNVAKVPASPT----LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL 311
Query: 357 DHRGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPS 411
+ + ++ P P + P S ASS + S SSSSSS SS S E DDL L LN S
Sbjct: 312 -YYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFS 370
Query: 412 SNFESMS---LGSFS-----SSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWL 463
+ S S LG + S S +D+DLD E GSHFEFPDYCTPE+SEMI+GDWL
Sbjct: 371 QSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWL 430
Query: 464 ESSISNLVFTY 474
E++ S+LVFTY
Sbjct: 431 EANFSDLVFTY 441
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 189 bits (481), Expect = 4e-48
Identities = 115/218 (52%), Positives = 135/218 (61%), Gaps = 30/218 (13%)
Query: 34 PTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRL 93
P PG + G A +P WCKTPSGHIKRPMNAFMVWSQ ERRKIM+Q PDMHNAEISKRL
Sbjct: 16 PPPGPGPAEEG-AREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRL 74
Query: 94 GKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGE 153
G+RW+LL+DS+KIPF+REAERLRLKHMADYPDYKYRPRKK S A A ++P
Sbjct: 75 GRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKK--------SKGAPAKARPRP 126
Query: 154 KGDKVGGSGGGGHGGGG----GGGSSNAGGG--GGGASGGGANSKPAQKKSCGSKVAGGA 207
GGSGGG G G G A GG GGGA+ + + ++ ++
Sbjct: 127 P----GGSGGGSRLKPGPQLPGRGGRRAAGGPLGGGAAAPEDDDEDDDEELLEVRLVETP 182
Query: 208 G---------GGVSKPHAKLILAGGGGGGKAAAAAAAS 236
G G ++ A+ A G G AAAAAAAS
Sbjct: 183 GRELWRMVPAGRAARGQAE--RAQGPSGEGAAAAAAAS 218
Score = 84.0 bits (206), Expect = 3e-16
Identities = 71/231 (30%), Positives = 95/231 (41%), Gaps = 40/231 (17%)
Query: 260 YKARTPSASASASS-----AASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGA 314
Y+ R S A A + S + PG L + GG + P+GG A
Sbjct: 109 YRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGR--------GGRRAAGGPLGGGAA 160
Query: 315 GADPSDP--------LGLYEEEGAGC---SPDAPSLSGRSSAASSPAAGRSPADHRGYAS 363
+ D + L E G P + G++ A P+ G A+
Sbjct: 161 APEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSG-------EGAAA 213
Query: 364 LRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFS 423
AASP PS + ++ + +S +E L L P +
Sbjct: 214 AAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGP--------AGL 265
Query: 424 SSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY 474
SALDRD D P SHFEFPDYCTPEV+EMI+GDW SSI++LVFTY
Sbjct: 266 DCSALDRDPDLQ-PPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY 315
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 144 bits (364), Expect = 1e-34
Identities = 114/363 (31%), Positives = 151/363 (41%), Gaps = 40/363 (11%)
Query: 20 SDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIME 79
S GA ++ G GG K +KRPMNAFMVWS+ +RRK+ +
Sbjct: 12 SPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQ 71
Query: 80 QSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNA 139
++P MHN+EISKRLG WK++ +++K PFI EA+RLR HM ++PDYKYRPR+K K+
Sbjct: 72 ENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLK 131
Query: 140 NSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSC 199
S A GG G GGGG + G G G A+ G P
Sbjct: 132 KDKYSLA------------GGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESP------ 173
Query: 200 GSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSL 259
G AGGG + + A G G AAAAAA+ ++A L
Sbjct: 174 ----GGAAGGGYAHVNG---WANGAYPGSVAAAAAAAAMMQEA---------------QL 211
Query: 260 YKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPS 319
+ P A + A A P H + Y G L S A PS
Sbjct: 212 AYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPS 271
Query: 320 DPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHAS 379
GL A + A S+ A++ AA + + G S S P+ A
Sbjct: 272 GYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAH 331
Query: 380 SSA 382
S A
Sbjct: 332 SRA 334
Score = 30.8 bits (68), Expect = 2.8
Identities = 30/120 (25%), Positives = 43/120 (35%), Gaps = 5/120 (4%)
Query: 119 HMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGG---GGGSS 175
H D +Y P S S+S + P + GG H ++
Sbjct: 247 HRYDMGALQYSPISN--SQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAA 304
Query: 176 NAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA 235
A G GA G S+P+ + G + + + + AG GG AAAAAAA
Sbjct: 305 AASSGALGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAA 364
Score = 29.3 bits (64), Expect = 8.1
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 21/93 (22%)
Query: 165 GHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGV-SKP--------H 215
G+GG G ++ A GGA A + A + S G G V S+P H
Sbjct: 272 GYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPAPAH 331
Query: 216 AK------------LILAGGGGGGKAAAAAAAS 236
++ + L G GG AAAAAAA+
Sbjct: 332 SRAPCPGDLREMISMYLPAGEGGDPAAAAAAAA 364
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 139 bits (350), Expect = 6e-33
Identities = 90/239 (37%), Positives = 121/239 (50%), Gaps = 26/239 (10%)
Query: 55 PSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAER 114
P H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WKLL +S+K PFI EA+R
Sbjct: 4 PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
Query: 115 LRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGD---KVGGSGGGGHGGGGG 171
LR HM ++PDYKYRPR+K K+ + G D +G G H G GG
Sbjct: 64 LRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGG 123
Query: 172 G---GSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGK 228
G S A A+ A ++ +S + A A P++ L L G K
Sbjct: 124 GLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDL-----GSK 178
Query: 229 AAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKH 287
A +++S A + GA A H +AA+A+AA AA G H
Sbjct: 179 MAEISSSSSGLPYASSLGYPTAGAGAFH---------------GAAAAAAAAAAAAGGH 222
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 129 bits (325), Expect = 4e-30
Identities = 107/331 (32%), Positives = 147/331 (44%), Gaps = 61/331 (18%)
Query: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
H+KRPMNAFMVW+Q RRK+ +Q P +HNAE+SK LGK W+LL +S+K PF+ EAERLR+
Sbjct: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
Query: 118 KHMADYPDYKYRP--RKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSS 175
+H D+PDYKY+P RK K+G+++S S A G H GGG +
Sbjct: 161 QHKKDHPDYKYQPRRRKSAKAGHSDSDSGAEL----------------GPHPGGGAVYKA 204
Query: 176 NAGGGGG---GASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAA 232
AG G G G G + P + +++ K + + G +
Sbjct: 205 EAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNV 264
Query: 233 AAASFAAEQAGAA---------ALLPLGAAA--DHHSLYKARTPSASASA----SSAASA 277
+ ++E G LPLG A + Y A AS SA SA
Sbjct: 265 DISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSA 324
Query: 278 SAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAP 337
SA+ G K ++ SP G Y ++ G SPD
Sbjct: 325 SASPTETGPPRPHIKTEQ----------PSP--------------GHYGDQPRG-SPDYG 359
Query: 338 SLSGRSSAASSPAAGRSPADHRGYASLRAAS 368
S SG+SSA + AG Y L+A+S
Sbjct: 360 SCSGQSSATPAAPAGPFAGSQGDYGDLQASS 390
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 128 bits (322), Expect = 1e-29
Identities = 72/170 (42%), Positives = 90/170 (52%), Gaps = 25/170 (14%)
Query: 13 ALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQI 72
A A SS SG G S PG+ P +KRPMNAFMVWS
Sbjct: 18 AATAAASSSSGPQEREGAGSPAAPGTL---------------PLEKVKRPMNAFMVWSSA 62
Query: 73 ERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRK 132
+RR++ +Q+P MHN+EISKRLG +WKLL + +K PF+ EA+RLR +H+ DYPDYKYRPR+
Sbjct: 63 QRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRR 122
Query: 133 KVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGG 182
K KS A P G G GG G G ++ G G
Sbjct: 123 KAKSSGAG----------PSRCGQGRGNLASGGPLWGPGYATTQPSRGFG 162
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 128 bits (321), Expect = 1e-29
Identities = 114/366 (31%), Positives = 148/366 (40%), Gaps = 61/366 (16%)
Query: 16 AGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERR 75
AG+SS + AG G S AS GG D +KRPMNAFMVWS+ +RR
Sbjct: 106 AGKSSANAAG---GANSGGGSSGGASGGGGGTDQD-------RVKRPMNAFMVWSRGQRR 155
Query: 76 KIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVK 135
K+ ++P MHN+EISKRLG WKLL D++K PFI EA+RLR HM +YPDYKYRPR+K K
Sbjct: 156 KMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTK 215
Query: 136 SGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQ 195
+ S + P G ++ A A+ + Q
Sbjct: 216 TLLKKDKYSLPSGLLP-------------------PGAAAAAAAAAAAAAAASSPVGVGQ 256
Query: 196 KKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA------SFAAEQ------AG 243
+ + V G A G S +L A A A Q G
Sbjct: 257 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPG 316
Query: 244 AAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLG 303
A + + + AAA S Y PSA+A+A++A A AA A
Sbjct: 317 AQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAA------------AA 364
Query: 304 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPD--------APSLSGRSSAASSPAAGRSP 355
S P+G V S P + C D P + AAS GR
Sbjct: 365 MSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLH 424
Query: 356 ADHRGY 361
H+ Y
Sbjct: 425 GVHQHY 430
Score = 43.1 bits (100), Expect = 5e-04
Identities = 62/282 (21%), Positives = 106/282 (37%), Gaps = 43/282 (15%)
Query: 157 KVGGSGGGGHGGGGGGGSSNAGGG--------GGGASGGGANSKPAQKKSCGSKVAGGAG 208
+ G+GG GG G S+NA GG GG + GGG + K+ + + G
Sbjct: 93 QAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRG 152
Query: 209 GGVS------KPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADH------ 256
K H I G K A ++A + + D+
Sbjct: 153 QRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRR 212
Query: 257 ----------HSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG-GLGTS 305
+SL P +A+A++AA+A+AA A+ + ++ ++ G G
Sbjct: 213 KTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAY 272
Query: 306 SSPVGGVGAGADPS----------DPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSP 355
S +G PS P+ Y+ G SP P G S + AA +
Sbjct: 273 SLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMP--PGAQSYMNVAAAAAAA 330
Query: 356 ADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSS 397
+ + G A A+ A + A+++A++ ++++ S G S
Sbjct: 331 SGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGS 372
Score = 37.4 bits (85), Expect = 0.030
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 11/63 (17%)
Query: 155 GDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKP 214
G +G GG GG G S+A GG SGGG+ S A G GGG +
Sbjct: 89 GTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGS-----------SGGASGGGGGTDQD 137
Query: 215 HAK 217
K
Sbjct: 138 RVK 140
Score = 30.4 bits (67), Expect = 3.7
Identities = 15/43 (34%), Positives = 18/43 (41%)
Query: 130 PRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGG 172
P + +G + A SS G GG GG GGGGG
Sbjct: 91 PTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGG 133
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 121 bits (304), Expect = 1e-27
Identities = 96/310 (30%), Positives = 133/310 (42%), Gaps = 55/310 (17%)
Query: 23 GAGLELGIASSPTPGSTAST-----GGKADDPS-----------------WCKTP----- 55
G G G+ +SP PG G+ADD W P
Sbjct: 35 GGGGGSGLRASPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRV 94
Query: 56 ------SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFI 109
H+KRPMNAFMVW+Q RRK+ +Q P +HNAE+SK LGK W+LL +SDK PFI
Sbjct: 95 NGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFI 154
Query: 110 REAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGG 169
EAERLR++H D+PDYKY+PR++ N ++ + PG + ++ G + H
Sbjct: 155 EEAERLRMQHKKDHPDYKYQPRRR-----KNGKAAQGEAECPGGEAEQGGTAAIQAHYKS 209
Query: 170 G-------GGGSSNAGGGGGGASG--GGANSKPAQKKS------CGSKVAGGAGGGVSKP 214
G GS + G SG G + P K+ K G + G KP
Sbjct: 210 AHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKP 269
Query: 215 HAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSA 274
H G + +F + A LP H S Y A ++ + A
Sbjct: 270 HIDFGNVDIGEISHEVMSNMETF--DVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVA 327
Query: 275 ASASAALAAP 284
+ SA ++ P
Sbjct: 328 SGHSAWISKP 337
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 121 bits (304), Expect = 1e-27
Identities = 53/82 (64%), Positives = 70/82 (85%)
Query: 55 PSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAER 114
PS HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WKLL +++K P+I EA+R
Sbjct: 4 PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
Query: 115 LRLKHMADYPDYKYRPRKKVKS 136
LR +HM ++PDYKYRPR+K K+
Sbjct: 64 LRAQHMKEHPDYKYRPRRKPKN 85
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 119 bits (298), Expect = 6e-27
Identities = 70/164 (42%), Positives = 90/164 (54%), Gaps = 19/164 (11%)
Query: 49 PSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPF 108
P K I+RPMNAFMVW++ ER+++ Q+PD+HNAE+SK LGK WK L S K P+
Sbjct: 35 PPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPY 94
Query: 109 IREAERLRLKHMADYPDYKYRPR---------KKVKSGNANSSSSAAASSKP-------- 151
+ EAERLRL+HM DYP+YKYRPR K+V G SS S ++ P
Sbjct: 95 VDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRG 154
Query: 152 --GEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKP 193
GEK D+ S G G GGGGG + ++ P
Sbjct: 155 ALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYP 198
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 119 bits (298), Expect = 6e-27
Identities = 53/89 (59%), Positives = 70/89 (78%), Gaps = 2/89 (2%)
Query: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
H+KRPMNAFMVW+Q RRK+ +Q P +HNAE+SK LGK W+LL +S+K PF+ EAERLR+
Sbjct: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
Query: 118 KHMADYPDYKYRP--RKKVKSGNANSSSS 144
+H D+PDYKY+P RK VK+G A + +
Sbjct: 164 QHKKDHPDYKYQPRRRKSVKNGQAEAEEA 192
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 119 bits (298), Expect = 6e-27
Identities = 70/163 (42%), Positives = 90/163 (55%), Gaps = 22/163 (13%)
Query: 34 PTPGSTASTGGKADDPSWC----KTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEI 89
P P T+ GG + K +KRPMNAFMVWS+ +RRK+ +++P MHN+EI
Sbjct: 12 PGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEI 71
Query: 90 SKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASS 149
SKRLG WKLL +++K PFI EA+RLR HM ++PDYKYRPR+K K+
Sbjct: 72 SKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKT------------- 118
Query: 150 KPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSK 192
K DK GG GG S +G G G G G N +
Sbjct: 119 --LMKKDKYTLPGG---LLAPGGNSMASGVGVGAGLGAGVNQR 156
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 114 bits (284), Expect = 3e-25
Identities = 60/136 (44%), Positives = 87/136 (63%), Gaps = 16/136 (11%)
Query: 37 GSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKR 96
G+ A G+A S I+RPMNAFMVW++ ER+++ +Q+PD+HNAE+SK LGK
Sbjct: 53 GAPAGAAGRAKGES-------RIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKS 105
Query: 97 WKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPR--------KKVKSGNANSSSSAAAS 148
WK L ++K PF+ EAERLR++HM D+P+YKYRPR K+V+ G + + A+
Sbjct: 106 WKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAA 165
Query: 149 SKPGEKGDKVGGSGGG 164
+ G +G +V G G
Sbjct: 166 AL-GPEGGRVAMDGLG 180
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 110 bits (276), Expect = 2e-24
Identities = 52/108 (48%), Positives = 76/108 (70%), Gaps = 4/108 (3%)
Query: 33 SPTPGSTA-STGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISK 91
SP PG S G+ + + I+RPMNAFMVW++ ER+++ +Q+PD+HNA +SK
Sbjct: 61 SPEPGRYGLSPAGRGERQA---ADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSK 117
Query: 92 RLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNA 139
LGK WK L ++K PF+ EAERLR++H+ D+P+YKYRPR+K ++ A
Sbjct: 118 MLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKA 165
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 104 bits (260), Expect = 2e-22
Identities = 46/78 (58%), Positives = 58/78 (74%)
Query: 56 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERL 115
S HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL
Sbjct: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
Query: 116 RLKHMADYPDYKYRPRKK 133
+H+ YPDYKY+PR K
Sbjct: 481 SRQHLEKYPDYKYKPRPK 498
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 103 bits (258), Expect = 3e-22
Identities = 49/100 (49%), Positives = 64/100 (64%)
Query: 34 PTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRL 93
PT G+T + D + HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK L
Sbjct: 609 PTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKIL 668
Query: 94 GKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKK 133
G RWK + + +K P+ E RL H+ YP+YKY+PR K
Sbjct: 669 GSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK 708
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 103 bits (258), Expect = 3e-22
Identities = 49/100 (49%), Positives = 64/100 (64%)
Query: 34 PTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRL 93
PT G+T + D + HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK L
Sbjct: 569 PTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKIL 628
Query: 94 GKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKK 133
G RWK + + +K P+ E RL H+ YP+YKY+PR K
Sbjct: 629 GSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK 668
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 103 bits (258), Expect = 3e-22
Identities = 49/100 (49%), Positives = 64/100 (64%)
Query: 34 PTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRL 93
PT G+T + D + HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK L
Sbjct: 572 PTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKIL 631
Query: 94 GKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKK 133
G RWK + + +K P+ E RL H+ YP+YKY+PR K
Sbjct: 632 GSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPK 671
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 103 bits (258), Expect = 3e-22
Identities = 56/130 (43%), Positives = 75/130 (57%), Gaps = 6/130 (4%)
Query: 9 ENTEALLAGESSDSGAGLELGIASSPTP-----GSTASTGGKADDPSWCKTPSGHIKRPM 63
EN L G+S++ G L G+ P G+T + D + HIKRPM
Sbjct: 547 ENLGPQLTGKSNEDGK-LGPGVIDLTRPEDAEGGATVAEARVYRDARGRASSEPHIKRPM 605
Query: 64 NAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADY 123
NAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL H+ Y
Sbjct: 606 NAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKY 665
Query: 124 PDYKYRPRKK 133
P+YKY+PR K
Sbjct: 666 PNYKYKPRPK 675
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 102 bits (255), Expect = 6e-22
Identities = 45/76 (59%), Positives = 57/76 (75%)
Query: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL
Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228
Query: 118 KHMADYPDYKYRPRKK 133
+H+ YPDYKY+PR K
Sbjct: 229 QHLEKYPDYKYKPRPK 244
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 102 bits (255), Expect = 6e-22
Identities = 45/76 (59%), Positives = 57/76 (75%)
Query: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL
Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601
Query: 118 KHMADYPDYKYRPRKK 133
+H+ YPDYKY+PR K
Sbjct: 602 QHLEKYPDYKYKPRPK 617
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 102 bits (255), Expect = 6e-22
Identities = 45/76 (59%), Positives = 57/76 (75%)
Query: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
Query: 118 KHMADYPDYKYRPRKK 133
+H+ YPDYKY+PR K
Sbjct: 615 QHLEKYPDYKYKPRPK 630
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 100 bits (248), Expect = 4e-21
Identities = 44/84 (52%), Positives = 64/84 (76%)
Query: 59 IKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLK 118
+KRPMNAF+VWS+ +RRK+ ++P M N+EISK+LG +WK+L +++K PF +EA++L+
Sbjct: 60 VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119
Query: 119 HMADYPDYKYRPRKKVKSGNANSS 142
H YP+YKYRPR+K K N S
Sbjct: 120 HREKYPNYKYRPRRKAKMLPKNCS 143
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 84.7 bits (208), Expect = 2e-16
Identities = 39/91 (42%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 41 STGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLL 100
S G D P + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L
Sbjct: 320 SDAGIPDTP-FSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKL 378
Query: 101 KDSDKIPFIREAERLRLKHMADYPDYKYRPR 131
+ K P+ EA++++ KH ++P + Y+PR
Sbjct: 379 SEEQKKPYYDEAQKIKEKHREEFPGWVYQPR 409
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 84.7 bits (208), Expect = 2e-16
Identities = 39/91 (42%), Positives = 59/91 (64%), Gaps = 1/91 (1%)
Query: 41 STGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLL 100
S G D P + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L
Sbjct: 320 SDAGIPDTP-FSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKL 378
Query: 101 KDSDKIPFIREAERLRLKHMADYPDYKYRPR 131
+ K P+ EA++++ KH ++P + Y+PR
Sbjct: 379 SEEQKKPYYDEAQKIKEKHREEFPGWVYQPR 409
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 84.7 bits (208), Expect = 2e-16
Identities = 84/284 (29%), Positives = 109/284 (38%), Gaps = 59/284 (20%)
Query: 142 SSSAAASSKPGEK-------------------GDKVGGSGGGGHGGGGGGGSSNAGGGGG 182
S+SAAA+ PG G G+GGGG GGGGGGG S GGGGG
Sbjct: 210 SASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Query: 183 GASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQA 242
GA GGA + + + A G GG GGG GG +A S +Q
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGG------------GGGYGGSSAGYGVLSSPRQQG 317
Query: 243 GAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGL 302
G + P G A + A+A SAA A +H + L
Sbjct: 318 GGMMMGPGGGGA---------ASLSKAAAGSAAGGFQRFAGQNQHPS----GATPTLNQL 364
Query: 303 GTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSL-SGRSSAASSPAAGRSPADHRGY 361
TS SP+ G+ P E P PS +++AA + A G+ A G
Sbjct: 365 LTSPSPMMRSYGGSYP-------EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 362 -----ASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSD 398
A AASPA ++A SH + S + + S S D
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/260 (27%), Positives = 98/260 (37%), Gaps = 34/260 (13%)
Query: 149 SKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAG 208
S+PG G GG GGGG G GGGG GGGG GA G GA + A + + GG G
Sbjct: 244 SRPGAGGGG-GGGGGGGGGSGGGG-----GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
Query: 209 GG----------VSKPHAK---LILAGGGGGGKAAAAAAASFAA---EQAGAAALLPLGA 252
GG +S P + +++ GGGG + + AAA AA ++ P GA
Sbjct: 298 GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGA 357
Query: 253 AADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGV 312
+ L + +P + S S+ A P + + G G+
Sbjct: 358 TPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP--PSQPQSQAAAAGAAAGGQQAAAGM 415
Query: 313 GAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPS 372
G G D + A SP + RS A SP +P G + P
Sbjct: 416 GLGKDMG-------AQYAAASPAWAAAQQRSHPAMSPG---TPGPTMGRSQGSPMDPMVM 465
Query: 373 SAPSHASSSASSHSSSSSSS 392
P ++ HS SS
Sbjct: 466 KRPQLYGMGSNPHSQPQQSS 485
Score = 49.3 bits (116), Expect = 8e-06
Identities = 64/273 (23%), Positives = 95/273 (34%), Gaps = 35/273 (12%)
Query: 151 PGEKGDKVGGSGGGGHGGGG-------GGGSSNAGGGGGGASGGGANSKPAQKKSCGSKV 203
P + +GG+GGG G GG +A GG G SKP + K+
Sbjct: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKM 134
Query: 204 AGGAGGGVSKP--------HAKLILAGGGGGGKAAA------AAAASFAAEQAGAAALLP 249
AGG P + + GGGGG A +AA + G A
Sbjct: 135 GEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA---- 190
Query: 250 LGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV------YLFGGLG 303
G D H ++ SAS+AA+ + P ++ E Y G G
Sbjct: 191 -GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249
Query: 304 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGY-- 361
GG G G+ G GAG A + + ++AA G GY
Sbjct: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309
Query: 362 -ASLRAASPAPSSAPSHASSSASSHSSSSSSSG 393
+S R P +++ S +++ S++G
Sbjct: 310 LSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 84.7 bits (208), Expect = 2e-16
Identities = 84/284 (29%), Positives = 109/284 (38%), Gaps = 59/284 (20%)
Query: 142 SSSAAASSKPGEK-------------------GDKVGGSGGGGHGGGGGGGSSNAGGGGG 182
S+SAAA+ PG G G+GGGG GGGGGGG S GGGGG
Sbjct: 210 SASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Query: 183 GASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQA 242
GA GGA + + + A G GG GGG GG +A S +Q
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGG------------GGGYGGSSAGYGVLSSPRQQG 317
Query: 243 GAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGL 302
G + P G A + A+A SAA A +H + L
Sbjct: 318 GGMMMGPGGGGA---------ASLSKAAAGSAAGGFQRFAGQNQHPS----GATPTLNQL 364
Query: 303 GTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSL-SGRSSAASSPAAGRSPADHRGY 361
TS SP+ G+ P E P PS +++AA + A G+ A G
Sbjct: 365 LTSPSPMMRSYGGSYP-------EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 362 -----ASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSD 398
A AASPA ++A SH + S + + S S D
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/260 (27%), Positives = 98/260 (37%), Gaps = 34/260 (13%)
Query: 149 SKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAG 208
S+PG G GG GGGG G GGGG GGGG GA G GA + A + + GG G
Sbjct: 244 SRPGAGGGG-GGGGGGGGGSGGGG-----GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
Query: 209 GG----------VSKPHAK---LILAGGGGGGKAAAAAAASFAA---EQAGAAALLPLGA 252
GG +S P + +++ GGGG + + AAA AA ++ P GA
Sbjct: 298 GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGA 357
Query: 253 AADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGV 312
+ L + +P + S S+ A P + + G G+
Sbjct: 358 TPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP--PSQPQSQAAAAGAAAGGQQAAAGM 415
Query: 313 GAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPS 372
G G D + A SP + RS A SP +P G + P
Sbjct: 416 GLGKDMG-------AQYAAASPAWAAAQQRSHPAMSPG---TPGPTMGRSQGSPMDPMVM 465
Query: 373 SAPSHASSSASSHSSSSSSS 392
P ++ HS SS
Sbjct: 466 KRPQLYGMGSNPHSQPQQSS 485
Score = 49.3 bits (116), Expect = 8e-06
Identities = 64/273 (23%), Positives = 95/273 (34%), Gaps = 35/273 (12%)
Query: 151 PGEKGDKVGGSGGGGHGGGG-------GGGSSNAGGGGGGASGGGANSKPAQKKSCGSKV 203
P + +GG+GGG G GG +A GG G SKP + K+
Sbjct: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKM 134
Query: 204 AGGAGGGVSKP--------HAKLILAGGGGGGKAAA------AAAASFAAEQAGAAALLP 249
AGG P + + GGGGG A +AA + G A
Sbjct: 135 GEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA---- 190
Query: 250 LGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV------YLFGGLG 303
G D H ++ SAS+AA+ + P ++ E Y G G
Sbjct: 191 -GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249
Query: 304 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGY-- 361
GG G G+ G GAG A + + ++AA G GY
Sbjct: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309
Query: 362 -ASLRAASPAPSSAPSHASSSASSHSSSSSSSG 393
+S R P +++ S +++ S++G
Sbjct: 310 LSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 84.7 bits (208), Expect = 2e-16
Identities = 84/284 (29%), Positives = 109/284 (38%), Gaps = 59/284 (20%)
Query: 142 SSSAAASSKPGEK-------------------GDKVGGSGGGGHGGGGGGGSSNAGGGGG 182
S+SAAA+ PG G G+GGGG GGGGGGG S GGGGG
Sbjct: 210 SASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Query: 183 GASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQA 242
GA GGA + + + A G GG GGG GG +A S +Q
Sbjct: 270 GAGAGGAGAGAVAAAAAAAAAAAGGGG------------GGGYGGSSAGYGVLSSPRQQG 317
Query: 243 GAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGL 302
G + P G A + A+A SAA A +H + L
Sbjct: 318 GGMMMGPGGGGA---------ASLSKAAAGSAAGGFQRFAGQNQHPS----GATPTLNQL 364
Query: 303 GTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSL-SGRSSAASSPAAGRSPADHRGY 361
TS SP+ G+ P E P PS +++AA + A G+ A G
Sbjct: 365 LTSPSPMMRSYGGSYP-------EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGL 417
Query: 362 -----ASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSD 398
A AASPA ++A SH + S + + S S D
Sbjct: 418 GKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMD 461
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/260 (27%), Positives = 98/260 (37%), Gaps = 34/260 (13%)
Query: 149 SKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAG 208
S+PG G GG GGGG G GGGG GGGG GA G GA + A + + GG G
Sbjct: 244 SRPGAGGGG-GGGGGGGGGSGGGG-----GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
Query: 209 GG----------VSKPHAK---LILAGGGGGGKAAAAAAASFAA---EQAGAAALLPLGA 252
GG +S P + +++ GGGG + + AAA AA ++ P GA
Sbjct: 298 GGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGA 357
Query: 253 AADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGV 312
+ L + +P + S S+ A P + + G G+
Sbjct: 358 TPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPP--PSQPQSQAAAAGAAAGGQQAAAGM 415
Query: 313 GAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPS 372
G G D + A SP + RS A SP +P G + P
Sbjct: 416 GLGKDMG-------AQYAAASPAWAAAQQRSHPAMSPG---TPGPTMGRSQGSPMDPMVM 465
Query: 373 SAPSHASSSASSHSSSSSSS 392
P ++ HS SS
Sbjct: 466 KRPQLYGMGSNPHSQPQQSS 485
Score = 49.3 bits (116), Expect = 8e-06
Identities = 64/273 (23%), Positives = 95/273 (34%), Gaps = 35/273 (12%)
Query: 151 PGEKGDKVGGSGGGGHGGGG-------GGGSSNAGGGGGGASGGGANSKPAQKKSCGSKV 203
P + +GG+GGG G GG +A GG G SKP + K+
Sbjct: 75 PISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKM 134
Query: 204 AGGAGGGVSKP--------HAKLILAGGGGGGKAAA------AAAASFAAEQAGAAALLP 249
AGG P + + GGGGG A +AA + G A
Sbjct: 135 GEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRA---- 190
Query: 250 LGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV------YLFGGLG 303
G D H ++ SAS+AA+ + P ++ E Y G G
Sbjct: 191 -GPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAG 249
Query: 304 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGY-- 361
GG G G+ G GAG A + + ++AA G GY
Sbjct: 250 GGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGV 309
Query: 362 -ASLRAASPAPSSAPSHASSSASSHSSSSSSSG 393
+S R P +++ S +++ S++G
Sbjct: 310 LSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAG 342
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 80.1 bits (196), Expect = 4e-15
Identities = 72/262 (27%), Positives = 90/262 (34%), Gaps = 47/262 (17%)
Query: 136 SGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQ 195
SG S G G G SGGGG+ GGG GG S+ GGGGGG G G S +
Sbjct: 29 SGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSV 88
Query: 196 KKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAAD 255
K S G +GG G S +GGGG G ++ S G +
Sbjct: 89 KYSGGGGSSGGGSGCFS--------SGGGGSGCFSSGGGGS----SGGGSGCF------- 129
Query: 256 HHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAG 315
+S S+ S ++ G F G GGV +G
Sbjct: 130 -----------SSGGGGSSGGGSGCFSSGGGG-----------FSGQAVQCQSYGGVSSG 167
Query: 316 ADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAP 375
G + G G S+ G S S G S GY S + + S AP
Sbjct: 168 GSSGGGSGCFSSGGGG-----GSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQT-SCAP 221
Query: 376 SHASSSASSHSSSSSSSGSSSS 397
+ SS S SG SS
Sbjct: 222 QPSYGGGSSGGGGSGGSGCFSS 243
Score = 60.1 bits (144), Expect = 4e-09
Identities = 59/224 (26%), Positives = 84/224 (37%), Gaps = 28/224 (12%)
Query: 136 SGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGG-------GGGSSNAGGGGGGASGGG 188
SG SS + G G SGGGG GGG GGGSS G G + GGG
Sbjct: 91 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150
Query: 189 ANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALL 248
+ + Q +S G +GG+ GG S + GGGGG + ++ +G
Sbjct: 151 FSGQAVQCQSYGGVSSGGSSGGGSG-----CFSSGGGGG-----SVCGYSGGGSGCGGGS 200
Query: 249 PLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSP 308
G+ + + S + S + S +S + G + GG G SS
Sbjct: 201 SGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG--------SGCFSSGGGGGSSGC 252
Query: 309 VG---GVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSP 349
G G+G+G S + +G S+ G S P
Sbjct: 253 GGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVP 296
Score = 39.7 bits (91), Expect = 0.006
Identities = 26/89 (29%), Positives = 33/89 (37%), Gaps = 17/89 (19%)
Query: 130 PRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGG----GGSSNAGGGGGGAS 185
P+ G++ S + G G GGG G G G GG S GGG G
Sbjct: 221 PQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGG 280
Query: 186 GGGANSKPAQKKSCGSKVAGGAGGGVSKP 214
GGG++ GG+G G P
Sbjct: 281 GGGSS-------------VGGSGSGKGVP 296
Score = 35.0 bits (79), Expect = 0.15
Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 136 SGNANSSSSAAASSKPGEKGDKVGGSG---GGGHGGGGGGGSSNAGGGGGGASGGGANSK 192
SG SS S G + G G GGG GGGGGG ++ GG G G +
Sbjct: 243 SGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG--SSVGGSGSGKGVPICHQ 300
Query: 193 PAQKKS 198
QK++
Sbjct: 301 TQQKQA 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.124 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,103,016
Number of Sequences: 37866
Number of extensions: 1241731
Number of successful extensions: 41708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 918
Number of HSP's successfully gapped in prelim test: 900
Number of HSP's that attempted gapping in prelim test: 11880
Number of HSP's gapped (non-prelim): 12495
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.