BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4507161 SRY-box 11 [Homo sapiens] (441 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4507161 SRY-box 11 [Homo sapiens] 885 0.0 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 291 1e-78 gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 223 2e-58 gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 139 4e-33 gi|5902108 SRY-box 21 [Homo sapiens] 134 2e-31 gi|5902106 SRY-box 15 [Homo sapiens] 124 1e-28 gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 123 3e-28 gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 123 4e-28 gi|4759162 SRY-box 14 [Homo sapiens] 122 5e-28 gi|13899269 SRY-box 7 [Homo sapiens] 120 3e-27 gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 119 4e-27 gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 115 8e-26 gi|4557853 transcription factor SOX9 [Homo sapiens] 115 1e-25 gi|11967991 SRY-box 17 [Homo sapiens] 115 1e-25 gi|8924248 SRY-box 18 [Homo sapiens] 111 1e-24 gi|41406089 SRY-box 13 [Homo sapiens] 107 2e-23 gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 105 8e-23 gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 105 8e-23 gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 105 8e-23 gi|4507225 sex determining region Y [Homo sapiens] 105 1e-22 gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 103 4e-22 gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 103 4e-22 gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 103 4e-22 gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 103 4e-22 gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 86 5e-17 gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 86 5e-17 gi|112421108 capicua homolog [Homo sapiens] 70 4e-12 gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 59 7e-09 gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 59 7e-09 gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 59 9e-09 >gi|4507161 SRY-box 11 [Homo sapiens] Length = 441 Score = 885 bits (2287), Expect = 0.0 Identities = 441/441 (100%), Positives = 441/441 (100%) Query: 1 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS Sbjct: 1 MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60 Query: 61 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP Sbjct: 61 KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120 Query: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA Sbjct: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180 Query: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK Sbjct: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240 Query: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG Sbjct: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300 Query: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD Sbjct: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360 Query: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE Sbjct: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420 Query: 421 LSEMIAGDWLEANFSDLVFTY 441 LSEMIAGDWLEANFSDLVFTY Sbjct: 421 LSEMIAGDWLEANFSDLVFTY 441 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 291 bits (744), Expect = 1e-78 Identities = 209/491 (42%), Positives = 258/491 (52%), Gaps = 67/491 (13%) Query: 1 MVQQAESLE-AESNLPREALDTEEGEFM--ACSPVALDES-------DPDWCKTASGHIK 50 MVQQ + E E+ L E+ D+ G + A SP + DP WCKT SGHIK Sbjct: 1 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60 Query: 51 RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM 110 RPMNAFMVWS+IERRKIMEQSPDMHNAEISKRLGKRWK+LKDS+KIPFIREAERLRLKHM Sbjct: 61 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120 Query: 111 ADYPDYKYRPRKKPK---MDPSAKPSASQSP----EKSAAGGGGGSAGGGAGGAKTSKGS 163 ADYPDYKYRPRKK K + S+ +AS P +K GGGG GGG GG+ + G Sbjct: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180 Query: 164 SKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCV--- 220 G + A +K K+ S GGAG ++ +GGGG GK Sbjct: 181 ----GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAAS 236 Query: 221 FLDED---------DDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQ--PSQLLRR 269 F E D + + L PG+ ++ R Sbjct: 237 FAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV 296 Query: 270 YNVAKVPASPT----LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL 311 Y + S + + + A+ + LY+E AG A+S A G S Sbjct: 297 YLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPA 356 Query: 312 -YYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFS 370 + + ++ P P + P S ASS + S SSSSSS SS S E DDL L LN S Sbjct: 357 DHRGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPS 411 Query: 371 QSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWL 430 + S S LG + S S +D+DLD E GSHFEFPDYCTPE+SEMI+GDWL Sbjct: 412 SNFESMS---LGSFS-----SSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWL 463 Query: 431 EANFSDLVFTY 441 E++ S+LVFTY Sbjct: 464 ESSISNLVFTY 474 >gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] Length = 315 Score = 223 bits (569), Expect = 2e-58 Identities = 156/405 (38%), Positives = 195/405 (48%), Gaps = 119/405 (29%) Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97 +P WCKT SGHIKRPMNAFMVWS+ ERRKIM+Q PDMHNAEISKRLG+RW++L+DSEKIP Sbjct: 29 EPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIP 88 Query: 98 FIREAERLRLKHMADYPDYKYRPRKKPKMDPS-AKPSASQSPEKSAAGGGGGSAGGGAGG 156 F+REAERLRLKHMADYPDYKYRPRKK K P+ A+P GG GG Sbjct: 89 FVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPR---------------PPGGSGGG 133 Query: 157 AKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKT 216 ++ G + P G +A G GGG A Sbjct: 134 SRLKPGP-------QLPGRGGRRAAGGPL-----------------------GGGAAA-- 161 Query: 217 VKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVP 276 EDDD+DDD++ L++ +L++ PG++ ++ VP Sbjct: 162 ------PEDDDEDDDEELLEV----------------RLVETPGRELWRM--------VP 191 Query: 277 ASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASS 336 A AE RA SG G A A SP S Sbjct: 192 AGRAARGQAE-----------RAQGPSGEGAA------------------AAAAASPTPS 222 Query: 337 RSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVD 396 +++ GE+ + SL F +L G A L S +D Sbjct: 223 EDEEPEEEEEE-AAAAEEGEEETVASGEESLGFL--------SRLPPGPA--GLDCSALD 271 Query: 397 KDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY 441 +D D S SHFEFPDYCTPE++EMIAGDW ++ +DLVFTY Sbjct: 272 RDPD-LQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY 315 >gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] Length = 391 Score = 139 bits (351), Expect = 4e-33 Identities = 104/322 (32%), Positives = 140/322 (43%), Gaps = 52/322 (16%) Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102 K +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK++ ++EK PFI EA Sbjct: 45 KANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104 Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKG 162 +RLR HM ++PDYKYRPR+K K +K + GG +AG G GGA + G Sbjct: 105 KRLRALHMKEHPDYKYRPRRKTK--------TLLKKDKYSLAGGLLAAGAGGGGAAVAMG 156 Query: 163 SSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFL 222 GA A + G G G +V G + G A + Sbjct: 157 ---------VGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMM- 206 Query: 223 DEDDDDDDDDDELQLQIKQEPDEEDEEP--------PHQQLLQPPGQQPSQLLRRYNVAK 274 E QL Q P P PH P QP + RY++ Sbjct: 207 ----------QEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQP---MHRYDMGA 253 Query: 275 VPASPTLSSS---AESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPAL 331 + SP +S + SP G A A + A GG+ Q+ A A Sbjct: 254 LQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAH----------QNSAVAAAAAA 303 Query: 332 SPASSRSVSTSSSSSSGSSSGS 353 + ASS ++ S SGS Sbjct: 304 AAASSGALGALGSLVKSEPSGS 325 Score = 36.6 bits (83), Expect = 0.047 Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 132 PSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKK 166 P+ P + GGGGG GGG GGAK ++ K+ Sbjct: 19 PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKR 53 >gi|5902108 SRY-box 21 [Homo sapiens] Length = 276 Score = 134 bits (337), Expect = 2e-31 Identities = 73/161 (45%), Positives = 97/161 (60%), Gaps = 19/161 (11%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L +SEK PFI EA+RLR Sbjct: 7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66 Query: 108 KHMADYPDYKYRPRKKP----KMDPSAKP--------SASQSPEKSAAGGGGGSAGGG-- 153 HM ++PDYKYRPR+KP K D A P + ++ P A G AGGG Sbjct: 67 MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126 Query: 154 -----AGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSG 189 A K + ++ ++ P +A A A A AA +G Sbjct: 127 PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAG 167 >gi|5902106 SRY-box 15 [Homo sapiens] Length = 233 Score = 124 bits (312), Expect = 1e-28 Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 10/114 (8%) Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108 +KRPMNAFMVWS +RR++ +Q+P MHN+EISKRLG +WK+L + EK PF+ EA+RLR + Sbjct: 49 VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108 Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGG---GAGGAKT 159 H+ DYPDYKYRPR+K K S+ P + G G ++GG G G A T Sbjct: 109 HLRDYPDYKYRPRRKAK-------SSGAGPSRCGQGRGNLASGGPLWGPGYATT 155 >gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] Length = 446 Score = 123 bits (309), Expect = 3e-28 Identities = 101/316 (31%), Positives = 138/316 (43%), Gaps = 85/316 (26%) Query: 44 TASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAE 103 T +KRPMNAFMVWS+ +RRK+ ++P MHN+EISKRLG WK+L D+EK PFI EA+ Sbjct: 134 TDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAK 193 Query: 104 RLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKT 159 RLR HM +YPDYKYRPR+K K D + PS P G +A A A Sbjct: 194 RLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPP--------GAAAAAAAAAA-- 243 Query: 160 SKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKC 219 A AAA + G G+ D Y V+G G Sbjct: 244 ------------AAAAASSPVGVGQRL---------DTYT----HVNGWANGAYSLV--- 275 Query: 220 VFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASP 279 + QL Q P P PP P + RY++A + SP Sbjct: 276 --------------QEQLGYAQPPSMSSPPP-------PPALPP---MHRYDMAGLQYSP 311 Query: 280 TLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSV 339 + P GA Y V A A + +G G P A A + A + Sbjct: 312 MM------PPGAQSYMNVAAAAAAASGYGGM-------------APSATAAAAAAYGQQP 352 Query: 340 STSSSSSSGSSSGSSG 355 +T++++++ +++ S G Sbjct: 353 ATAAAAAAAAAAMSLG 368 Score = 32.3 bits (72), Expect = 0.88 Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 14/59 (23%) Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKA-AQSGDYGGAGDDYV 199 AAG GG +A GGA GK A AA GA +G G + SG GG D V Sbjct: 94 AAGTGGPAAPGGA-------------GKSSANAAGGANSGGGSSGGASGGGGGTDQDRV 139 Score = 29.6 bits (65), Expect = 5.7 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 8/69 (11%) Query: 124 PKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAG 183 P M P A+ + + +AA G GG A A + G + PA A A A A Sbjct: 311 PMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG--------QQPATAAAAAAAA 362 Query: 184 KAAQSGDYG 192 A G G Sbjct: 363 AAMSLGPMG 371 >gi|28195386 sex-determining region Y-box 2 [Homo sapiens] Length = 317 Score = 123 bits (308), Expect = 4e-28 Identities = 63/118 (53%), Positives = 80/118 (67%), Gaps = 5/118 (4%) Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102 K + +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L ++EK PFI EA Sbjct: 35 KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94 Query: 103 ERLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSP-EKSAAGGGGGSAGGGAG 155 +RLR HM ++PDYKYRPR+K K D P +P S A G G AG GAG Sbjct: 95 KRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAG 152 >gi|4759162 SRY-box 14 [Homo sapiens] Length = 240 Score = 122 bits (307), Expect = 5e-28 Identities = 53/80 (66%), Positives = 69/80 (86%) Query: 46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105 S HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG WK+L ++EK P+I EA+RL Sbjct: 5 SDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRL 64 Query: 106 RLKHMADYPDYKYRPRKKPK 125 R +HM ++PDYKYRPR+KPK Sbjct: 65 RAQHMKEHPDYKYRPRRKPK 84 >gi|13899269 SRY-box 7 [Homo sapiens] Length = 388 Score = 120 bits (300), Expect = 3e-27 Identities = 74/180 (41%), Positives = 96/180 (53%), Gaps = 41/180 (22%) Query: 18 ALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNA 77 ALD E + SP A+ D K + I+RPMNAFMVW+K ER+++ Q+PD+HNA Sbjct: 18 ALDAELSDGQ--SPPAVPRPPGD--KGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNA 73 Query: 78 EISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKK-------PKMDP-- 128 E+SK LGK WK L S+K P++ EAERLRL+HM DYP+YKYRPR+K ++DP Sbjct: 74 ELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGF 133 Query: 129 ---SAKPSASQSPEKSAAGGGG-------------------------GSAGGGAGGAKTS 160 S + PEK + G G AGGG GG +S Sbjct: 134 LLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSS 193 >gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] Length = 446 Score = 119 bits (299), Expect = 4e-27 Identities = 64/149 (42%), Positives = 84/149 (56%), Gaps = 27/149 (18%) Query: 45 ASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAER 104 A H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAER Sbjct: 98 AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157 Query: 105 LRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSS 164 LR++H D+PDYKY+PR++ KSA G S G G G+ Sbjct: 158 LRVQHKKDHPDYKYQPRRR----------------KSAKAGHSDSDSGAELGPHPGGGAV 201 Query: 165 KKCGKLKAPAAAGAKAGAGKAAQSGDYGG 193 K A+AG G GD+ G Sbjct: 202 YK-----------AEAGLGDGHHHGDHTG 219 >gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] Length = 466 Score = 115 bits (288), Expect = 8e-26 Identities = 52/99 (52%), Positives = 72/99 (72%), Gaps = 2/99 (2%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +S+K PFI EAERLR+ Sbjct: 103 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRM 162 Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGG 146 +H D+PDYKY+PR+ + + A ++ P A GG Sbjct: 163 QHKKDHPDYKYQPRR--RKNGKAAQGEAECPGGEAEQGG 199 >gi|4557853 transcription factor SOX9 [Homo sapiens] Length = 509 Score = 115 bits (287), Expect = 1e-25 Identities = 50/94 (53%), Positives = 73/94 (77%), Gaps = 1/94 (1%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAERLR+ Sbjct: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163 Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKS 141 +H D+PDYKY+PR++ K + + A ++ E++ Sbjct: 164 QHKKDHPDYKYQPRRR-KSVKNGQAEAEEATEQT 196 >gi|11967991 SRY-box 17 [Homo sapiens] Length = 414 Score = 115 bits (287), Expect = 1e-25 Identities = 53/105 (50%), Positives = 75/105 (71%), Gaps = 5/105 (4%) Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108 I+RPMNAFMVW+K ER+++ +Q+PD+HNAE+SK LGK WK L +EK PF+ EAERLR++ Sbjct: 68 IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQ 127 Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSAS-----QSPEKSAAGGGGG 148 HM D+P+YKYRPR++ ++ + P+ +A G GG Sbjct: 128 HMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGG 172 >gi|8924248 SRY-box 18 [Homo sapiens] Length = 384 Score = 111 bits (278), Expect = 1e-24 Identities = 47/75 (62%), Positives = 64/75 (85%) Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108 I+RPMNAFMVW+K ER+++ +Q+PD+HNA +SK LGK WK L +EK PF+ EAERLR++ Sbjct: 85 IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144 Query: 109 HMADYPDYKYRPRKK 123 H+ D+P+YKYRPR+K Sbjct: 145 HLRDHPNYKYRPRRK 159 >gi|41406089 SRY-box 13 [Homo sapiens] Length = 622 Score = 107 bits (268), Expect = 2e-23 Identities = 48/78 (61%), Positives = 58/78 (74%) Query: 46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105 S HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480 Query: 106 RLKHMADYPDYKYRPRKK 123 +H+ YPDYKY+PR K Sbjct: 481 SRQHLEKYPDYKYKPRPK 498 >gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo sapiens] Length = 377 Score = 105 bits (262), Expect = 8e-23 Identities = 47/76 (61%), Positives = 57/76 (75%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228 Query: 108 KHMADYPDYKYRPRKK 123 +H+ YPDYKY+PR K Sbjct: 229 QHLEKYPDYKYKPRPK 244 >gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo sapiens] Length = 750 Score = 105 bits (262), Expect = 8e-23 Identities = 47/76 (61%), Positives = 57/76 (75%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 Query: 108 KHMADYPDYKYRPRKK 123 +H+ YPDYKY+PR K Sbjct: 602 QHLEKYPDYKYKPRPK 617 >gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo sapiens] Length = 763 Score = 105 bits (262), Expect = 8e-23 Identities = 47/76 (61%), Positives = 57/76 (75%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614 Query: 108 KHMADYPDYKYRPRKK 123 +H+ YPDYKY+PR K Sbjct: 615 QHLEKYPDYKYKPRPK 630 >gi|4507225 sex determining region Y [Homo sapiens] Length = 204 Score = 105 bits (261), Expect = 1e-22 Identities = 46/80 (57%), Positives = 64/80 (80%) Query: 49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108 +KRPMNAF+VWS+ +RRK+ ++P M N+EISK+LG +WKML ++EK PF +EA++L+ Sbjct: 60 VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119 Query: 109 HMADYPDYKYRPRKKPKMDP 128 H YP+YKYRPR+K KM P Sbjct: 120 HREKYPNYKYRPRRKAKMLP 139 >gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo sapiens] Length = 841 Score = 103 bits (256), Expect = 4e-22 Identities = 46/76 (60%), Positives = 56/76 (73%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692 Query: 108 KHMADYPDYKYRPRKK 123 H+ YP+YKY+PR K Sbjct: 693 IHLEKYPNYKYKPRPK 708 >gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo sapiens] Length = 801 Score = 103 bits (256), Expect = 4e-22 Identities = 46/76 (60%), Positives = 56/76 (73%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652 Query: 108 KHMADYPDYKYRPRKK 123 H+ YP+YKY+PR K Sbjct: 653 IHLEKYPNYKYKPRPK 668 >gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo sapiens] Length = 804 Score = 103 bits (256), Expect = 4e-22 Identities = 46/76 (60%), Positives = 56/76 (73%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655 Query: 108 KHMADYPDYKYRPRKK 123 H+ YP+YKY+PR K Sbjct: 656 IHLEKYPNYKYKPRPK 671 >gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo sapiens] Length = 808 Score = 103 bits (256), Expect = 4e-22 Identities = 46/76 (60%), Positives = 56/76 (73%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659 Query: 108 KHMADYPDYKYRPRKK 123 H+ YP+YKY+PR K Sbjct: 660 IHLEKYPNYKYKPRPK 675 >gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo sapiens] Length = 501 Score = 86.3 bits (212), Expect = 5e-17 Identities = 36/84 (42%), Positives = 57/84 (67%) Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97 D + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L + +K P Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385 Query: 98 FIREAERLRLKHMADYPDYKYRPR 121 + EA++++ KH ++P + Y+PR Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409 >gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo sapiens] Length = 753 Score = 86.3 bits (212), Expect = 5e-17 Identities = 36/84 (42%), Positives = 57/84 (67%) Query: 38 DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97 D + K +GH+KRPMNAFMVW++I R + + +P +NAEIS +LG W L + +K P Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385 Query: 98 FIREAERLRLKHMADYPDYKYRPR 121 + EA++++ KH ++P + Y+PR Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 70.1 bits (170), Expect = 4e-12 Identities = 96/407 (23%), Positives = 153/407 (37%), Gaps = 88/407 (21%) Query: 43 KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102 K HI+RPMNAFM++SK R + ++ P+ N +SK LG+ W L EK + A Sbjct: 194 KREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLA 253 Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSA-------SQSPEKSAAGGGGGSAGGGAG 155 +++ H +PD+K+ + + K AKP++ ++ E+S + G +A G + Sbjct: 254 FQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSS 313 Query: 156 -----------GAKTSKGSSKKCG-----KLKAPAAAGAKAGAGKAAQSGDYGGAGDDYV 199 + T S CG + P +A +A + S D GG D Sbjct: 314 ELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLD-GGEVDSQA 372 Query: 200 LGSLRVSGSG------------------------GGGAGKTVKCVFL-------DEDDDD 228 L L SG GG T + L + Sbjct: 373 LQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASE 432 Query: 229 DDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESP 288 D DE ++ I +E ++D ++ G + + + +V S + SS E P Sbjct: 433 DMTSDEERMVICEEEGDDD-------VIADDGFGTTDIDLKCK-ERVTDSESGDSSGEDP 484 Query: 289 EGASLYDEVRAGATSGAGGGSRLY-----YSFKNITKQHPPPLAQPALSPASSRSVSTSS 343 EG G G +++ SF + P P P + S+ Sbjct: 485 EG-------------NKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSA 531 Query: 344 SSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNL 390 SSS SS SS A + +FS + + Q+ G G+ AG L Sbjct: 532 PSSSASSPASSSASA-------ATSFSLGSGTFKAQESGQGSTAGPL 571 >gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] Length = 442 Score = 59.3 bits (142), Expect = 7e-09 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIK+P+NAFM++ K R K++ + +A I++ LG+RW L E+ + A + R Sbjct: 326 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 385 Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142 HM YP + R KK K +P + +KSA Sbjct: 386 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 422 >gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] Length = 489 Score = 59.3 bits (142), Expect = 7e-09 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%) Query: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 HIK+P+NAFM++ K R K++ + +A I++ LG+RW L E+ + A + R Sbjct: 373 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 432 Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142 HM YP + R KK K +P + +KSA Sbjct: 433 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 469 >gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo sapiens] Length = 2191 Score = 58.9 bits (141), Expect = 9e-09 Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 32/253 (12%) Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAA---QSGDYGGAGDDY 198 A GGGGG GGG G G G A A A A A A AA G YGG+ Y Sbjct: 248 AGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307 Query: 199 -VLGSLR------VSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPP 251 VL S R + G GGGGA K Q Q P Sbjct: 308 GVLSSPRQQGGGMMMGPGGGGAASLSKAA-------AGSAAGGFQRFAGQNQHPSGATPT 360 Query: 252 HQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRL 311 QLL PS ++R Y + P SS + P S + +A A A GG + Sbjct: 361 LNQLL----TSPSPMMRSYG----GSYPEYSSPSAPPPPPS-QPQSQAAAAGAAAGGQQA 411 Query: 312 YYSF---KNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSG-SSGEDADDLMFDLSL 367 K++ Q+ A PA + A RS S + G + G S G D ++ Sbjct: 412 AAGMGLGKDMGAQY--AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQ 469 Query: 368 NFSQSAHSASEQQ 380 + ++ S+ Q Sbjct: 470 LYGMGSNPHSQPQ 482 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.127 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,932,622 Number of Sequences: 37866 Number of extensions: 1125830 Number of successful extensions: 24123 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 638 Number of HSP's successfully gapped in prelim test: 628 Number of HSP's that attempted gapping in prelim test: 11900 Number of HSP's gapped (non-prelim): 7512 length of query: 441 length of database: 18,247,518 effective HSP length: 105 effective length of query: 336 effective length of database: 14,271,588 effective search space: 4795253568 effective search space used: 4795253568 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.