Guide to the Human Genome
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Search of human proteins with 4507161

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507161 SRY-box 11 [Homo sapiens]
         (441 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507161 SRY-box 11 [Homo sapiens]                                  885   0.0  
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        291   1e-78
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      223   2e-58
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       139   4e-33
gi|5902108 SRY-box 21 [Homo sapiens]                                  134   2e-31
gi|5902106 SRY-box 15 [Homo sapiens]                                  124   1e-28
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]       123   3e-28
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]             123   4e-28
gi|4759162 SRY-box 14 [Homo sapiens]                                  122   5e-28
gi|13899269 SRY-box 7 [Homo sapiens]                                  120   3e-27
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]       119   4e-27
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]       115   8e-26
gi|4557853 transcription factor SOX9 [Homo sapiens]                   115   1e-25
gi|11967991 SRY-box 17 [Homo sapiens]                                 115   1e-25
gi|8924248 SRY-box 18 [Homo sapiens]                                  111   1e-24
gi|41406089 SRY-box 13 [Homo sapiens]                                 107   2e-23
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   105   8e-23
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   105   8e-23
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   105   8e-23
gi|4507225 sex determining region Y [Homo sapiens]                    105   1e-22
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...   103   4e-22
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...   103   4e-22
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...   103   4e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...   103   4e-22
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    86   5e-17
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    86   5e-17
gi|112421108 capicua homolog [Homo sapiens]                            70   4e-12
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]    59   7e-09
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]    59   7e-09
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    59   9e-09

>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  885 bits (2287), Expect = 0.0
 Identities = 441/441 (100%), Positives = 441/441 (100%)

Query: 1   MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60
           MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS
Sbjct: 1   MVQQAESLEAESNLPREALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWS 60

Query: 61  KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120
           KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP
Sbjct: 61  KIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRP 120

Query: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180
           RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA
Sbjct: 121 RKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKA 180

Query: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240
           GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK
Sbjct: 181 GAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIK 240

Query: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300
           QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG
Sbjct: 241 QEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAG 300

Query: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360
           ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD
Sbjct: 301 ATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADD 360

Query: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420
           LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE
Sbjct: 361 LMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPE 420

Query: 421 LSEMIAGDWLEANFSDLVFTY 441
           LSEMIAGDWLEANFSDLVFTY
Sbjct: 421 LSEMIAGDWLEANFSDLVFTY 441


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  291 bits (744), Expect = 1e-78
 Identities = 209/491 (42%), Positives = 258/491 (52%), Gaps = 67/491 (13%)

Query: 1   MVQQAESLE-AESNLPREALDTEEGEFM--ACSPVALDES-------DPDWCKTASGHIK 50
           MVQQ  + E  E+ L  E+ D+  G  +  A SP     +       DP WCKT SGHIK
Sbjct: 1   MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK 60

Query: 51  RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM 110
           RPMNAFMVWS+IERRKIMEQSPDMHNAEISKRLGKRWK+LKDS+KIPFIREAERLRLKHM
Sbjct: 61  RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM 120

Query: 111 ADYPDYKYRPRKKPK---MDPSAKPSASQSP----EKSAAGGGGGSAGGGAGGAKTSKGS 163
           ADYPDYKYRPRKK K    + S+  +AS  P    +K    GGGG  GGG GG+  + G 
Sbjct: 121 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG 180

Query: 164 SKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCV--- 220
               G   +   A +K    K+  S   GGAG        ++  +GGGG GK        
Sbjct: 181 ----GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAAS 236

Query: 221 FLDED---------DDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQ--PSQLLRR 269
           F  E              D     + +                 L  PG+     ++ R 
Sbjct: 237 FAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRV 296

Query: 270 YNVAKVPASPT----LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL 311
           Y    +  S +    + + A+  +   LY+E  AG              A+S A G S  
Sbjct: 297 YLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPA 356

Query: 312 -YYSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFS 370
            +  + ++    P P + P  S ASS + S SSSSSS  SS S  E  DDL   L LN S
Sbjct: 357 DHRGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPS 411

Query: 371 QSAHSASEQQLGGGAAAGNLSLSLVDKDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWL 430
            +  S S   LG  +     S S +D+DLD   E   GSHFEFPDYCTPE+SEMI+GDWL
Sbjct: 412 SNFESMS---LGSFS-----SSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWL 463

Query: 431 EANFSDLVFTY 441
           E++ S+LVFTY
Sbjct: 464 ESSISNLVFTY 474


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  223 bits (569), Expect = 2e-58
 Identities = 156/405 (38%), Positives = 195/405 (48%), Gaps = 119/405 (29%)

Query: 38  DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
           +P WCKT SGHIKRPMNAFMVWS+ ERRKIM+Q PDMHNAEISKRLG+RW++L+DSEKIP
Sbjct: 29  EPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIP 88

Query: 98  FIREAERLRLKHMADYPDYKYRPRKKPKMDPS-AKPSASQSPEKSAAGGGGGSAGGGAGG 156
           F+REAERLRLKHMADYPDYKYRPRKK K  P+ A+P                  GG  GG
Sbjct: 89  FVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPR---------------PPGGSGGG 133

Query: 157 AKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKT 216
           ++   G        + P   G +A  G                         GGG A   
Sbjct: 134 SRLKPGP-------QLPGRGGRRAAGGPL-----------------------GGGAAA-- 161

Query: 217 VKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVP 276
                  EDDD+DDD++ L++                +L++ PG++  ++        VP
Sbjct: 162 ------PEDDDEDDDEELLEV----------------RLVETPGRELWRM--------VP 191

Query: 277 ASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASS 336
           A       AE           RA   SG G                    A  A SP  S
Sbjct: 192 AGRAARGQAE-----------RAQGPSGEGAA------------------AAAAASPTPS 222

Query: 337 RSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVD 396
                       +++   GE+      + SL F          +L  G A   L  S +D
Sbjct: 223 EDEEPEEEEEE-AAAAEEGEEETVASGEESLGFL--------SRLPPGPA--GLDCSALD 271

Query: 397 KDLDSFSEGSLGSHFEFPDYCTPELSEMIAGDWLEANFSDLVFTY 441
           +D D     S  SHFEFPDYCTPE++EMIAGDW  ++ +DLVFTY
Sbjct: 272 RDPD-LQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY 315


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  139 bits (351), Expect = 4e-33
 Identities = 104/322 (32%), Positives = 140/322 (43%), Gaps = 52/322 (16%)

Query: 43  KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
           K     +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK++ ++EK PFI EA
Sbjct: 45  KANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEA 104

Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKG 162
           +RLR  HM ++PDYKYRPR+K K             +K +  GG  +AG G GGA  + G
Sbjct: 105 KRLRALHMKEHPDYKYRPRRKTK--------TLLKKDKYSLAGGLLAAGAGGGGAAVAMG 156

Query: 163 SSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKCVFL 222
                         GA A   +    G   G G  +V G    +  G   A      +  
Sbjct: 157 ---------VGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMM- 206

Query: 223 DEDDDDDDDDDELQLQIKQEPDEEDEEP--------PHQQLLQPPGQQPSQLLRRYNVAK 274
                      E QL   Q P      P        PH     P   QP   + RY++  
Sbjct: 207 ----------QEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQP---MHRYDMGA 253

Query: 275 VPASPTLSSS---AESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPAL 331
           +  SP  +S    + SP G        A A + A GG+           Q+    A  A 
Sbjct: 254 LQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAH----------QNSAVAAAAAA 303

Query: 332 SPASSRSVSTSSSSSSGSSSGS 353
           + ASS ++    S      SGS
Sbjct: 304 AAASSGALGALGSLVKSEPSGS 325



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 15/35 (42%), Positives = 20/35 (57%)

Query: 132 PSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKK 166
           P+    P  +  GGGGG  GGG GGAK ++   K+
Sbjct: 19  PTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKR 53


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score =  134 bits (337), Expect = 2e-31
 Identities = 73/161 (45%), Positives = 97/161 (60%), Gaps = 19/161 (11%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK+L +SEK PFI EA+RLR 
Sbjct: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66

Query: 108 KHMADYPDYKYRPRKKP----KMDPSAKP--------SASQSPEKSAAGGGGGSAGGG-- 153
            HM ++PDYKYRPR+KP    K D  A P        + ++ P   A  G    AGGG  
Sbjct: 67  MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126

Query: 154 -----AGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSG 189
                A   K +  ++    ++  P +A A A A  AA +G
Sbjct: 127 PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAG 167


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score =  124 bits (312), Expect = 1e-28
 Identities = 60/114 (52%), Positives = 79/114 (69%), Gaps = 10/114 (8%)

Query: 49  IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
           +KRPMNAFMVWS  +RR++ +Q+P MHN+EISKRLG +WK+L + EK PF+ EA+RLR +
Sbjct: 49  VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108

Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGG---GAGGAKT 159
           H+ DYPDYKYRPR+K K       S+   P +   G G  ++GG   G G A T
Sbjct: 109 HLRDYPDYKYRPRRKAK-------SSGAGPSRCGQGRGNLASGGPLWGPGYATT 155


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score =  123 bits (309), Expect = 3e-28
 Identities = 101/316 (31%), Positives = 138/316 (43%), Gaps = 85/316 (26%)

Query: 44  TASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAE 103
           T    +KRPMNAFMVWS+ +RRK+  ++P MHN+EISKRLG  WK+L D+EK PFI EA+
Sbjct: 134 TDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAK 193

Query: 104 RLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKT 159
           RLR  HM +YPDYKYRPR+K     K D  + PS    P        G +A   A  A  
Sbjct: 194 RLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPP--------GAAAAAAAAAA-- 243

Query: 160 SKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKC 219
                       A AAA +  G G+           D Y      V+G   G        
Sbjct: 244 ------------AAAAASSPVGVGQRL---------DTYT----HVNGWANGAYSLV--- 275

Query: 220 VFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASP 279
                         + QL   Q P      P       PP   P   + RY++A +  SP
Sbjct: 276 --------------QEQLGYAQPPSMSSPPP-------PPALPP---MHRYDMAGLQYSP 311

Query: 280 TLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSV 339
            +      P GA  Y  V A A + +G G                P A  A + A  +  
Sbjct: 312 MM------PPGAQSYMNVAAAAAAASGYGGM-------------APSATAAAAAAYGQQP 352

Query: 340 STSSSSSSGSSSGSSG 355
           +T++++++ +++ S G
Sbjct: 353 ATAAAAAAAAAAMSLG 368



 Score = 32.3 bits (72), Expect = 0.88
 Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 14/59 (23%)

Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKA-AQSGDYGGAGDDYV 199
           AAG GG +A GGA             GK  A AA GA +G G +   SG  GG   D V
Sbjct: 94  AAGTGGPAAPGGA-------------GKSSANAAGGANSGGGSSGGASGGGGGTDQDRV 139



 Score = 29.6 bits (65), Expect = 5.7
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 124 PKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAG 183
           P M P A+   + +   +AA G GG A      A  + G        + PA A A A A 
Sbjct: 311 PMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG--------QQPATAAAAAAAA 362

Query: 184 KAAQSGDYG 192
            A   G  G
Sbjct: 363 AAMSLGPMG 371


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score =  123 bits (308), Expect = 4e-28
 Identities = 63/118 (53%), Positives = 80/118 (67%), Gaps = 5/118 (4%)

Query: 43  KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
           K +   +KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK+L ++EK PFI EA
Sbjct: 35  KNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEA 94

Query: 103 ERLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSP-EKSAAGGGGGSAGGGAG 155
           +RLR  HM ++PDYKYRPR+K     K D    P    +P   S A G G  AG GAG
Sbjct: 95  KRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAG 152


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  122 bits (307), Expect = 5e-28
 Identities = 53/80 (66%), Positives = 69/80 (86%)

Query: 46  SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105
           S HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK+L ++EK P+I EA+RL
Sbjct: 5   SDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRL 64

Query: 106 RLKHMADYPDYKYRPRKKPK 125
           R +HM ++PDYKYRPR+KPK
Sbjct: 65  RAQHMKEHPDYKYRPRRKPK 84


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  120 bits (300), Expect = 3e-27
 Identities = 74/180 (41%), Positives = 96/180 (53%), Gaps = 41/180 (22%)

Query: 18  ALDTEEGEFMACSPVALDESDPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNA 77
           ALD E  +    SP A+     D  K +   I+RPMNAFMVW+K ER+++  Q+PD+HNA
Sbjct: 18  ALDAELSDGQ--SPPAVPRPPGD--KGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNA 73

Query: 78  EISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKYRPRKK-------PKMDP-- 128
           E+SK LGK WK L  S+K P++ EAERLRL+HM DYP+YKYRPR+K        ++DP  
Sbjct: 74  ELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGF 133

Query: 129 ---SAKPSASQSPEKSAAGGGG-------------------------GSAGGGAGGAKTS 160
              S     +  PEK +   G                          G AGGG GG  +S
Sbjct: 134 LLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSS 193


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score =  119 bits (299), Expect = 4e-27
 Identities = 64/149 (42%), Positives = 84/149 (56%), Gaps = 27/149 (18%)

Query: 45  ASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAER 104
           A  H+KRPMNAFMVW++  RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAER
Sbjct: 98  AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157

Query: 105 LRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSS 164
           LR++H  D+PDYKY+PR++                KSA  G   S  G   G     G+ 
Sbjct: 158 LRVQHKKDHPDYKYQPRRR----------------KSAKAGHSDSDSGAELGPHPGGGAV 201

Query: 165 KKCGKLKAPAAAGAKAGAGKAAQSGDYGG 193
            K           A+AG G     GD+ G
Sbjct: 202 YK-----------AEAGLGDGHHHGDHTG 219


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score =  115 bits (288), Expect = 8e-26
 Identities = 52/99 (52%), Positives = 72/99 (72%), Gaps = 2/99 (2%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           H+KRPMNAFMVW++  RRK+ +Q P +HNAE+SK LGK W++L +S+K PFI EAERLR+
Sbjct: 103 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRM 162

Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGG 146
           +H  D+PDYKY+PR+  + +  A    ++ P   A  GG
Sbjct: 163 QHKKDHPDYKYQPRR--RKNGKAAQGEAECPGGEAEQGG 199


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score =  115 bits (287), Expect = 1e-25
 Identities = 50/94 (53%), Positives = 73/94 (77%), Gaps = 1/94 (1%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           H+KRPMNAFMVW++  RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAERLR+
Sbjct: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163

Query: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKS 141
           +H  D+PDYKY+PR++ K   + +  A ++ E++
Sbjct: 164 QHKKDHPDYKYQPRRR-KSVKNGQAEAEEATEQT 196


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  115 bits (287), Expect = 1e-25
 Identities = 53/105 (50%), Positives = 75/105 (71%), Gaps = 5/105 (4%)

Query: 49  IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
           I+RPMNAFMVW+K ER+++ +Q+PD+HNAE+SK LGK WK L  +EK PF+ EAERLR++
Sbjct: 68  IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQ 127

Query: 109 HMADYPDYKYRPRKKPKMDPSAKPSAS-----QSPEKSAAGGGGG 148
           HM D+P+YKYRPR++ ++    +           P+ +A G  GG
Sbjct: 128 HMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGG 172


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  111 bits (278), Expect = 1e-24
 Identities = 47/75 (62%), Positives = 64/75 (85%)

Query: 49  IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
           I+RPMNAFMVW+K ER+++ +Q+PD+HNA +SK LGK WK L  +EK PF+ EAERLR++
Sbjct: 85  IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144

Query: 109 HMADYPDYKYRPRKK 123
           H+ D+P+YKYRPR+K
Sbjct: 145 HLRDHPNYKYRPRRK 159


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score =  107 bits (268), Expect = 2e-23
 Identities = 48/78 (61%), Positives = 58/78 (74%)

Query: 46  SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105
           S HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL
Sbjct: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480

Query: 106 RLKHMADYPDYKYRPRKK 123
             +H+  YPDYKY+PR K
Sbjct: 481 SRQHLEKYPDYKYKPRPK 498


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  105 bits (262), Expect = 8e-23
 Identities = 47/76 (61%), Positives = 57/76 (75%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228

Query: 108 KHMADYPDYKYRPRKK 123
           +H+  YPDYKY+PR K
Sbjct: 229 QHLEKYPDYKYKPRPK 244


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  105 bits (262), Expect = 8e-23
 Identities = 47/76 (61%), Positives = 57/76 (75%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601

Query: 108 KHMADYPDYKYRPRKK 123
           +H+  YPDYKY+PR K
Sbjct: 602 QHLEKYPDYKYKPRPK 617


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  105 bits (262), Expect = 8e-23
 Identities = 47/76 (61%), Positives = 57/76 (75%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614

Query: 108 KHMADYPDYKYRPRKK 123
           +H+  YPDYKY+PR K
Sbjct: 615 QHLEKYPDYKYKPRPK 630


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score =  105 bits (261), Expect = 1e-22
 Identities = 46/80 (57%), Positives = 64/80 (80%)

Query: 49  IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLK 108
           +KRPMNAF+VWS+ +RRK+  ++P M N+EISK+LG +WKML ++EK PF +EA++L+  
Sbjct: 60  VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119

Query: 109 HMADYPDYKYRPRKKPKMDP 128
           H   YP+YKYRPR+K KM P
Sbjct: 120 HREKYPNYKYRPRRKAKMLP 139


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score =  103 bits (256), Expect = 4e-22
 Identities = 46/76 (60%), Positives = 56/76 (73%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692

Query: 108 KHMADYPDYKYRPRKK 123
            H+  YP+YKY+PR K
Sbjct: 693 IHLEKYPNYKYKPRPK 708


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score =  103 bits (256), Expect = 4e-22
 Identities = 46/76 (60%), Positives = 56/76 (73%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652

Query: 108 KHMADYPDYKYRPRKK 123
            H+  YP+YKY+PR K
Sbjct: 653 IHLEKYPNYKYKPRPK 668


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score =  103 bits (256), Expect = 4e-22
 Identities = 46/76 (60%), Positives = 56/76 (73%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655

Query: 108 KHMADYPDYKYRPRKK 123
            H+  YP+YKY+PR K
Sbjct: 656 IHLEKYPNYKYKPRPK 671


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score =  103 bits (256), Expect = 4e-22
 Identities = 46/76 (60%), Positives = 56/76 (73%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL  
Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659

Query: 108 KHMADYPDYKYRPRKK 123
            H+  YP+YKY+PR K
Sbjct: 660 IHLEKYPNYKYKPRPK 675


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 36/84 (42%), Positives = 57/84 (67%)

Query: 38  DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
           D  + K  +GH+KRPMNAFMVW++I R  + + +P  +NAEIS +LG  W  L + +K P
Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385

Query: 98  FIREAERLRLKHMADYPDYKYRPR 121
           +  EA++++ KH  ++P + Y+PR
Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 36/84 (42%), Positives = 57/84 (67%)

Query: 38  DPDWCKTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIP 97
           D  + K  +GH+KRPMNAFMVW++I R  + + +P  +NAEIS +LG  W  L + +K P
Sbjct: 326 DTPFSKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKP 385

Query: 98  FIREAERLRLKHMADYPDYKYRPR 121
           +  EA++++ KH  ++P + Y+PR
Sbjct: 386 YYDEAQKIKEKHREEFPGWVYQPR 409


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 96/407 (23%), Positives = 153/407 (37%), Gaps = 88/407 (21%)

Query: 43  KTASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREA 102
           K    HI+RPMNAFM++SK  R  + ++ P+  N  +SK LG+ W  L   EK  +   A
Sbjct: 194 KREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLA 253

Query: 103 ERLRLKHMADYPDYKYRPRKKPKMDPSAKPSA-------SQSPEKSAAGGGGGSAGGGAG 155
            +++  H   +PD+K+  + + K    AKP++        ++ E+S +  G  +A G + 
Sbjct: 254 FQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSS 313

Query: 156 -----------GAKTSKGSSKKCG-----KLKAPAAAGAKAGAGKAAQSGDYGGAGDDYV 199
                       + T    S  CG      +  P +A  +A +     S D GG  D   
Sbjct: 314 ELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLD-GGEVDSQA 372

Query: 200 LGSLRVSGSG------------------------GGGAGKTVKCVFL-------DEDDDD 228
           L  L    SG                        GG    T +   L            +
Sbjct: 373 LQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASE 432

Query: 229 DDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESP 288
           D   DE ++ I +E  ++D       ++   G   + +  +    +V  S +  SS E P
Sbjct: 433 DMTSDEERMVICEEEGDDD-------VIADDGFGTTDIDLKCK-ERVTDSESGDSSGEDP 484

Query: 289 EGASLYDEVRAGATSGAGGGSRLY-----YSFKNITKQHPPPLAQPALSPASSRSVSTSS 343
           EG               G G +++      SF +      P    P   P +      S+
Sbjct: 485 EG-------------NKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSA 531

Query: 344 SSSSGSSSGSSGEDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNL 390
            SSS SS  SS   A       + +FS  + +   Q+ G G+ AG L
Sbjct: 532 PSSSASSPASSSASA-------ATSFSLGSGTFKAQESGQGSTAGPL 571


>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
          Length = 442

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIK+P+NAFM++ K  R K++ +     +A I++ LG+RW  L   E+  +   A + R 
Sbjct: 326 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 385

Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142
            HM  YP +  R    KK K     +P  +   +KSA
Sbjct: 386 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 422


>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
          Length = 489

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 2/97 (2%)

Query: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
           HIK+P+NAFM++ K  R K++ +     +A I++ LG+RW  L   E+  +   A + R 
Sbjct: 373 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 432

Query: 108 KHMADYPDYKYRPR--KKPKMDPSAKPSASQSPEKSA 142
            HM  YP +  R    KK K     +P  +   +KSA
Sbjct: 433 LHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEKKSA 469


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 72/253 (28%), Positives = 93/253 (36%), Gaps = 32/253 (12%)

Query: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAA---QSGDYGGAGDDY 198
           A GGGGG  GGG G      G     G   A A A A A A  AA     G YGG+   Y
Sbjct: 248 AGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGY 307

Query: 199 -VLGSLR------VSGSGGGGAGKTVKCVFLDEDDDDDDDDDELQLQIKQEPDEEDEEPP 251
            VL S R      + G GGGGA    K                 Q    Q        P 
Sbjct: 308 GVLSSPRQQGGGMMMGPGGGGAASLSKAA-------AGSAAGGFQRFAGQNQHPSGATPT 360

Query: 252 HQQLLQPPGQQPSQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRAGATSGAGGGSRL 311
             QLL      PS ++R Y      + P  SS +  P   S   + +A A   A GG + 
Sbjct: 361 LNQLL----TSPSPMMRSYG----GSYPEYSSPSAPPPPPS-QPQSQAAAAGAAAGGQQA 411

Query: 312 YYSF---KNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSG-SSGEDADDLMFDLSL 367
                  K++  Q+    A PA + A  RS    S  + G + G S G   D ++     
Sbjct: 412 AAGMGLGKDMGAQY--AAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQ 469

Query: 368 NFSQSAHSASEQQ 380
            +   ++  S+ Q
Sbjct: 470 LYGMGSNPHSQPQ 482


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,932,622
Number of Sequences: 37866
Number of extensions: 1125830
Number of successful extensions: 24123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 638
Number of HSP's successfully gapped in prelim test: 628
Number of HSP's that attempted gapping in prelim test: 11900
Number of HSP's gapped (non-prelim): 7512
length of query: 441
length of database: 18,247,518
effective HSP length: 105
effective length of query: 336
effective length of database: 14,271,588
effective search space: 4795253568
effective search space used: 4795253568
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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