Guide to the Human Genome
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Name: EGF Sequence: fasta or formatted (1207aa) NCBI GI: 166362728
Description:

epidermal growth factor (beta-urogastrone)

Referenced in:

Epidermal Growth Factor
Lipoproteins
Additional Protein Modifications
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         60           2
 C cysteine            5.4         65           1
 D aspartate           6.5         78           2
 E glutamate           5.9         71           2
 F phenylalanine       2.7         32           1
 G glycine             8.4        101           2
 H histidine           3.1         38           2
 I isoleucine          4.6         55           2
 K lysine              4.6         56           2
 L leucine             8.9        107           4
 M methionine          2.6         31           1
 N asparagine          3.8         46           2
 P proline             5.1         62           3
 Q glutamine           4.4         53           3
 R arginine            4.7         57           3
 S serine              8.5        102           3
 T threonine           4.1         49           1
 V valine              6.9         83           3
 W tryptophan          2.2         27           2
 Y tyrosine            2.8         34           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   epidermal growth factor (beta-urogastrone) 
LRP4                  0.106   low density lipoprotein receptor-related protein 4 ...
LRP1                  0.097   low density lipoprotein-related protein 1 
LRP5                  0.089   low density lipoprotein receptor-related protein 5 ...
LRP8                  0.085   low density lipoprotein receptor-related protein 8 i...
LRP8                  0.085   low density lipoprotein receptor-related protein 8 i...
LRP8                  0.085   low density lipoprotein receptor-related protein 8 i...
LRP6                  0.085   low density lipoprotein receptor-related protein 6 ...
LRP8                  0.085   low density lipoprotein receptor-related protein 8 i...
LRP2                  0.083   low density lipoprotein-related protein 2 
LDLR                  0.081   low density lipoprotein receptor precursor 
LRP1B                 0.080   low density lipoprotein-related protein 1B precursor...
VLDLR                 0.076   very low density lipoprotein receptor isoform b [Hom...
VLDLR                 0.076   very low density lipoprotein receptor isoform a [Hom...
NID1                  0.055   nidogen 1 precursor 
NID2                  0.048   nidogen 2 precursor 
LRP5L                 0.044   low density lipoprotein receptor-related protein 5-l...
LRP5L                 0.044   low density lipoprotein receptor-related protein 5-...
SORL1                 0.039   sortilin-related receptor containing LDLR class A rep...
FBN2                  0.038   fibrillin 2 precursor 
MEGF6                 0.038   EGF-like-domain, multiple 3 
MATN2                 0.038   matrilin 2 isoform b precursor 
MATN2                 0.038   matrilin 2 isoform a precursor 
FBN1                  0.038   fibrillin 1 precursor 
MATN3                 0.036   matrilin 3 precursor 
FBN3                  0.033   fibrillin 3 precursor 
SCUBE2                0.031   CEGP1 protein 
MATN4                 0.031   matrilin 4 isoform 1 precursor 
SCUBE1                0.030   signal peptide, CUB domain, EGF-like 1 
HMCN1                 0.029   hemicentin 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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