Search of human proteins with 4506143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506143 neurotrypsin precursor [Homo sapiens]
         (875 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506143 neurotrypsin precursor [Homo sapiens]                     1894   0.0  
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...   371   e-102
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...   369   e-102
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]     362   e-100
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...   358   9e-99
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]     356   6e-98
gi|44889963 CD163 antigen isoform b [Homo sapiens]                    329   8e-90
gi|44662834 CD163 antigen isoform a [Homo sapiens]                    329   8e-90
gi|18152779 scavenger receptor cysteine rich domain containing, ...   328   1e-89
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...   306   4e-83
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            284   2e-76
gi|5174411 CD5 molecule-like [Homo sapiens]                           243   7e-64
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             228   1e-59
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              211   2e-54
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           211   2e-54
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             211   3e-54
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         187   3e-47
gi|29244926 corin [Homo sapiens]                                      179   1e-44
gi|4503627 coagulation factor XI precursor [Homo sapiens]             178   2e-44
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           176   6e-44
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein...   172   9e-43
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei...   172   9e-43
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   172   1e-42
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   172   1e-42
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa...   171   3e-42
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot...   171   3e-42
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           171   3e-42
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          171   4e-42
gi|223942069 enterokinase precursor [Homo sapiens]                    170   5e-42
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          170   5e-42

>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score = 1894 bits (4905), Expect = 0.0
 Identities = 875/875 (100%), Positives = 875/875 (100%)

Query: 1   MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYPYYLPTQQRPPTTRPPP 60
           MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYPYYLPTQQRPPTTRPPP
Sbjct: 1   MTLARFVLALMLGALPEVVGFDSVLNDSLHHSHRHSPPAGPHYPYYLPTQQRPPTTRPPP 60

Query: 61  PLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLRWAEVPPFLE 120
           PLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLRWAEVPPFLE
Sbjct: 61  PLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLRWAEVPPFLE 120

Query: 121 RSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFE 180
           RSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFE
Sbjct: 121 RSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFE 180

Query: 181 GTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCR 240
           GTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCR
Sbjct: 181 GTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCR 240

Query: 241 GDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQ 300
           GDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQ
Sbjct: 241 GDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQ 300

Query: 301 WGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCP 360
           WGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCP
Sbjct: 301 WGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCP 360

Query: 361 KSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELN 420
           KSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELN
Sbjct: 361 KSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELN 420

Query: 421 TYVVCRQLGFKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHRED 480
           TYVVCRQLGFKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHRED
Sbjct: 421 TYVVCRQLGFKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHRED 480

Query: 481 VSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQ 540
           VSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQ
Sbjct: 481 VSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQ 540

Query: 541 LGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICD 600
           LGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICD
Sbjct: 541 LGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICD 600

Query: 601 YFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLL 660
           YFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLL
Sbjct: 601 YFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLL 660

Query: 661 CGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRP 720
           CGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRP
Sbjct: 661 CGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRP 720

Query: 721 DRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRT 780
           DRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRT
Sbjct: 721 DRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRT 780

Query: 781 LQQAAIPLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVV 840
           LQQAAIPLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVV
Sbjct: 781 LQQAAIPLLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVV 840

Query: 841 YGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL 875
           YGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL
Sbjct: 841 YGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL 875


>gi|148539842 deleted in malignant brain tumors 1 isoform b
           precursor [Homo sapiens]
          Length = 2413

 Score =  371 bits (952), Expect = e-102
 Identities = 200/473 (42%), Positives = 249/473 (52%), Gaps = 44/473 (9%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279
             PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481

Query: 280 ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                       +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541

Query: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT-PLTDGV 386
            A   A FG+GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C+ P +   
Sbjct: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLA 601

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEEST 445
           +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQLG  +   A  N  F + +
Sbjct: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661

Query: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY------------------- 486
           GPI LDDV CSG E+    C    W  H+C H ED  + C                    
Sbjct: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLP 721

Query: 487 PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGP 546
           P   G   SL   +RL++G ++ +GRVEV   G WGT+CDD W   DA V+CRQLG    
Sbjct: 722 PSTVGSESSL--TLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 779

Query: 547 ARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
             A   A FG+G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 780 TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 832



 Score =  359 bits (921), Expect = 7e-99
 Identities = 197/495 (39%), Positives = 248/495 (50%), Gaps = 67/495 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  GS   +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+       
Sbjct: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840

Query: 381  ---------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900

Query: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960

Query: 485  CYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGTI 524
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT+
Sbjct: 961  C---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 1017

Query: 525  CDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDI 584
            CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C     
Sbjct: 1018 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 1077

Query: 585  GRHNCRHSEDAGVIC 599
              HNC HSEDAGVIC
Sbjct: 1078 LSHNCGHSEDAGVIC 1092



 Score =  358 bits (920), Expect = 9e-99
 Identities = 199/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 861  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279
              PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980

Query: 280  ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------T 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       T
Sbjct: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100

Query: 381  PLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425
            P  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1160

Query: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 1161 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1220

Query: 485  CYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
            C                 H  + G      +RL++G ++ +GRVEV   G WGT+CDD W
Sbjct: 1221 CSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 1280

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 1281 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1340

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1341 GHHEDAGVIC 1350



 Score =  356 bits (913), Expect = 6e-98
 Identities = 197/496 (39%), Positives = 246/496 (49%), Gaps = 68/496 (13%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------ 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+      
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 381 ----------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 341 TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 484 ACYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGT 523
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT
Sbjct: 461 IC---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517

Query: 524 ICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQD 583
           +CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C    
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577

Query: 584 IGRHNCRHSEDAGVIC 599
              HNC HSEDAGVIC
Sbjct: 578 WLSHNCGHSEDAGVIC 593



 Score =  355 bits (911), Expect = 1e-97
 Identities = 197/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1369

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 1490 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609

Query: 487  PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                                L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 1610 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1669

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 1670 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1730 GHHEDAGVIC 1739



 Score =  354 bits (908), Expect = 2e-97
 Identities = 198/490 (40%), Positives = 247/490 (50%), Gaps = 61/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1121 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1180

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 1181 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1240

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQ
Sbjct: 1361 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC- 485
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480

Query: 486  ------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                        +P       G   +L   +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSWGTVCDDYW 1538

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 1539 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1598

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1599 GHHEDAGVIC 1608



 Score =  261 bits (666), Expect = 3e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1508 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1567

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 1568 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1747

Query: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 1748 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1803

Query: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 1804 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1862

Query: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 1863 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1917

Query: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 1918 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1977

Query: 592  SEDAGVIC 599
             EDAGVIC
Sbjct: 1978 REDAGVIC 1985



 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 1639 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1698

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 1699 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1758

Query: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 1759 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1818

Query: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 1819 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1873

Query: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 1874 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1933

Query: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 1934 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1989

Query: 494  LSLGFP 499
            LS   P
Sbjct: 1990 LSTPAP 1995



 Score =  112 bits (280), Expect = 1e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201


>gi|148539844 deleted in malignant brain tumors 1 isoform c
           precursor [Homo sapiens]
          Length = 2403

 Score =  369 bits (948), Expect = e-102
 Identities = 199/464 (42%), Positives = 248/464 (53%), Gaps = 36/464 (7%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPI--------- 279
             PI   +VRC G E  +  C  + W    C     A V CS +  PT  +         
Sbjct: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTL-PTITLPASTVGSES 480

Query: 280 ---IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFG 336
              +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A   A FG
Sbjct: 481 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 540

Query: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT-PLTDGVIRLAGGKGS 395
           +GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C+ P +   +RL  G   
Sbjct: 541 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDR 600

Query: 396 HEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVS 454
            +GR+EV YRG WGTVCDD W   +  VVCRQLG  +   A  N  F + +GPI LDDV 
Sbjct: 601 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 660

Query: 455 CSGKETRFLQCSRRQWGRHDCSHREDVSIACY-------------------PGGEGHRLS 495
           CSG E+    C    W  H+C H ED  + C                    P   G   S
Sbjct: 661 CSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESS 720

Query: 496 LGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYF 555
           L   +RL++G ++ +GRVEV   G WGT+CDD W   DA V+CRQLG      A   A F
Sbjct: 721 L--TLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF 778

Query: 556 GEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           G+G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 779 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 822



 Score =  359 bits (921), Expect = 7e-99
 Identities = 197/495 (39%), Positives = 248/495 (50%), Gaps = 67/495 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 591  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 650

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 651  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 710

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  GS   +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 711  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 770

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+       
Sbjct: 771  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 830

Query: 381  ---------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 831  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 890

Query: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 891  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 950

Query: 485  CYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGTI 524
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT+
Sbjct: 951  C---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 1007

Query: 525  CDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDI 584
            CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C     
Sbjct: 1008 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 1067

Query: 585  GRHNCRHSEDAGVIC 599
              HNC HSEDAGVIC
Sbjct: 1068 LSHNCGHSEDAGVIC 1082



 Score =  358 bits (920), Expect = 9e-99
 Identities = 198/485 (40%), Positives = 247/485 (50%), Gaps = 56/485 (11%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------ 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+      
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 381 ----------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 341 TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 484 AC--------YPGGE-GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDA 534
            C         P    G   SL   +RL++G ++ +GRVEV   G WGT+CDD W   DA
Sbjct: 461 ICSDTLPTITLPASTVGSESSLA--LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 518

Query: 535 AVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSED 594
            V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C       HNC HSED
Sbjct: 519 NVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED 578

Query: 595 AGVIC 599
           AGVIC
Sbjct: 579 AGVIC 583



 Score =  358 bits (920), Expect = 9e-99
 Identities = 199/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 851  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 910

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279
              PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 911  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 970

Query: 280  ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 971  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1030

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------T 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       T
Sbjct: 1031 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1090

Query: 381  PLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425
            P  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 1091 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1150

Query: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 1151 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1210

Query: 485  CYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
            C                 H  + G      +RL++G ++ +GRVEV   G WGT+CDD W
Sbjct: 1211 CSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 1270

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 1271 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1330

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1331 GHHEDAGVIC 1340



 Score =  355 bits (911), Expect = 1e-97
 Identities = 197/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1240 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1299

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 1300 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1359

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 1360 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1419

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 1420 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1479

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 1480 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1539

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 1540 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1599

Query: 487  PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                                L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 1600 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1659

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 1660 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1719

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1720 GHHEDAGVIC 1729



 Score =  354 bits (908), Expect = 2e-97
 Identities = 198/490 (40%), Positives = 247/490 (50%), Gaps = 61/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1111 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1170

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 1171 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1230

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 1231 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1290

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 1291 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1350

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQ
Sbjct: 1351 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1410

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC- 485
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 1411 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1470

Query: 486  ------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                        +P       G   +L   +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 1471 ASQSQPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSWGTVCDDYW 1528

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 1529 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1588

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1589 GHHEDAGVIC 1598



 Score =  261 bits (666), Expect = 3e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 1498 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1557

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 1558 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1617

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 1618 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1677

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 1678 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1737

Query: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 1738 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1793

Query: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 1794 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1852

Query: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 1853 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1907

Query: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 1908 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1967

Query: 592  SEDAGVIC 599
             EDAGVIC
Sbjct: 1968 REDAGVIC 1975



 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 1629 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1688

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 1689 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1748

Query: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 1749 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1808

Query: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 1809 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1863

Query: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 1864 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1923

Query: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 1924 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1979

Query: 494  LSLGFP 499
            LS   P
Sbjct: 1980 LSTPAP 1985



 Score =  112 bits (280), Expect = 1e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score =  362 bits (930), Expect = e-100
 Identities = 199/493 (40%), Positives = 249/493 (50%), Gaps = 62/493 (12%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279
             PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481

Query: 280 ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                       +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541

Query: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
            A   A FG+GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C+       
Sbjct: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPT 601

Query: 381 ------------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTY 422
                             P +   +RL  G    +GR+EV YRG WGTVCDD W   +  
Sbjct: 602 PIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 661

Query: 423 VVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDV 481
           VVCRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED 
Sbjct: 662 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDA 721

Query: 482 SIACYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICD 526
            + C                 H  + G      +RL++G ++ +GRVEV   G WGT+CD
Sbjct: 722 GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 781

Query: 527 DGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGR 586
           D W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       
Sbjct: 782 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 841

Query: 587 HNCRHSEDAGVIC 599
           HNC HSEDAGVIC
Sbjct: 842 HNCGHSEDAGVIC 854



 Score =  356 bits (913), Expect = 6e-98
 Identities = 199/496 (40%), Positives = 246/496 (49%), Gaps = 68/496 (13%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC------- 379
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 380 TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424
           TP  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 484 ACYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGT 523
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT
Sbjct: 461 IC---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517

Query: 524 ICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQD 583
           +CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C    
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577

Query: 584 IGRHNCRHSEDAGVIC 599
              HNC HSEDAGVIC
Sbjct: 578 WLSHNCGHSEDAGVIC 593



 Score =  354 bits (908), Expect = 2e-97
 Identities = 196/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 625  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 684

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 685  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHA 744

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 745  STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 804

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 805  PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 864

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 865  PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 924

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 925  LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 984

Query: 487  PGGEGH-------------RLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                                L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 985  AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1044

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 1045 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1104

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1105 GHHEDAGVIC 1114



 Score =  261 bits (666), Expect = 3e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 883  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 942

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 943  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1002

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 1003 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1062

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 1063 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1122

Query: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 1123 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1178

Query: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 1179 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1237

Query: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 1238 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1292

Query: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 1293 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1352

Query: 592  SEDAGVIC 599
             EDAGVIC
Sbjct: 1353 REDAGVIC 1360



 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 1014 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1073

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 1074 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1133

Query: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 1134 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1193

Query: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 1194 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1248

Query: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 1249 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1308

Query: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 1309 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1364

Query: 494  LSLGFP 499
            LS   P
Sbjct: 1365 LSTPAP 1370



 Score =  112 bits (280), Expect = 1e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201


>gi|148539840 deleted in malignant brain tumors 1 isoform a
           precursor [Homo sapiens]
          Length = 1785

 Score =  358 bits (920), Expect = 9e-99
 Identities = 199/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279
             PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481

Query: 280 ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                       +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541

Query: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------T 380
            A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       T
Sbjct: 542 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 601

Query: 381 PLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425
           P  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 602 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 661

Query: 426 RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484
           RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 662 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 721

Query: 485 CYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
           C                 H  + G      +RL++G ++ +GRVEV   G WGT+CDD W
Sbjct: 722 CSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 781

Query: 530 TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
              DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 782 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 841

Query: 590 RHSEDAGVIC 599
            H EDAGVIC
Sbjct: 842 GHHEDAGVIC 851



 Score =  355 bits (910), Expect = 1e-97
 Identities = 197/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 622  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 681

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 682  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 741

Query: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 742  STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 801

Query: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 802  PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 861

Query: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
             D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 862  PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 921

Query: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 922  LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 981

Query: 487  PGGEGH-------------RLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                                L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 982  AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1041

Query: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
               DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 1042 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1101

Query: 590  RHSEDAGVIC 599
             H EDAGVIC
Sbjct: 1102 GHHEDAGVIC 1111



 Score =  354 bits (909), Expect = 2e-97
 Identities = 196/496 (39%), Positives = 246/496 (49%), Gaps = 68/496 (13%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------ 380
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+      
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 381 ----------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 341 TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 484 ACYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGT 523
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT
Sbjct: 461 IC---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 517

Query: 524 ICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQD 583
           +CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C    
Sbjct: 518 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 577

Query: 584 IGRHNCRHSEDAGVIC 599
              HNC HSEDAGVIC
Sbjct: 578 WLSHNCGHSEDAGVIC 593



 Score =  261 bits (666), Expect = 3e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 880  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 939

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 940  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 999

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 1000 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1059

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 1060 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1119

Query: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 1120 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1175

Query: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 1176 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1234

Query: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 1235 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1289

Query: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 1290 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1349

Query: 592  SEDAGVIC 599
             EDAGVIC
Sbjct: 1350 REDAGVIC 1357



 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 1011 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1070

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 1071 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1130

Query: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 1131 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1190

Query: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 1191 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1245

Query: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 1246 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1305

Query: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 1306 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1361

Query: 494  LSLGFP 499
            LS   P
Sbjct: 1362 LSTPAP 1367



 Score =  112 bits (280), Expect = 1e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score =  356 bits (913), Expect = 6e-98
 Identities = 196/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G   +A      G G
Sbjct: 499 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 558

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
             PI   +VRC G+E  +  C  + W    C     A V CS +   + P          
Sbjct: 559 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHA 618

Query: 279 ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
                     +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 619 STAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 678

Query: 330 WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382
              A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 679 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 738

Query: 383 TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427
            D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 739 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 798

Query: 428 LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486
           LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 799 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 858

Query: 487 PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529
                               L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 859 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 918

Query: 530 TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589
              DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 919 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 978

Query: 590 RHSEDAGVIC 599
            H EDAGVIC
Sbjct: 979 GHHEDAGVIC 988



 Score =  355 bits (910), Expect = 1e-97
 Identities = 199/499 (39%), Positives = 246/499 (49%), Gaps = 68/499 (13%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220

Query: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC------- 379
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       
Sbjct: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340

Query: 380 TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424
           TP  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400

Query: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460

Query: 484 ACYPG--------GEGHRLSL---------------GFPVRLMDGENKKEGRVEVFINGQ 520
            C           GE  R                     +RL++G ++ +GRVEV   G 
Sbjct: 461 ICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGS 520

Query: 521 WGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCI 580
           WGT+CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C 
Sbjct: 521 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 580

Query: 581 KQDIGRHNCRHSEDAGVIC 599
                 HNC HSEDAGVIC
Sbjct: 581 HNGWLSHNCGHSEDAGVIC 599



 Score =  354 bits (908), Expect = 2e-97
 Identities = 200/498 (40%), Positives = 249/498 (50%), Gaps = 69/498 (13%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG-------------- 274
             PI   +VRC G E  +  C  + W    C     A V CS +H               
Sbjct: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDT 481

Query: 275 -PTFPI------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQL 321
            PT  +            +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQL
Sbjct: 482 LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541

Query: 322 GLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-- 379
           G      A   A FG+GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C  
Sbjct: 542 GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSA 601

Query: 380 -----TPLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTEL 419
                TP  D                 +RL  G    +GR+EV Y+G WGTVCDD W   
Sbjct: 602 AQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 661

Query: 420 NTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHR 478
           +  VVCRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H 
Sbjct: 662 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 721

Query: 479 EDVSIAC-------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQW 521
           ED  + C             +P       G   +L   +RL++G ++  GRVEV   G W
Sbjct: 722 EDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSW 779

Query: 522 GTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIK 581
           GT+CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C  
Sbjct: 780 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPH 839

Query: 582 QDIGRHNCRHSEDAGVIC 599
                HNC H EDAGVIC
Sbjct: 840 NGWLSHNCGHHEDAGVIC 857



 Score =  261 bits (666), Expect = 3e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 757  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 816

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 817  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 876

Query: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 877  PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936

Query: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 937  SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 996

Query: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 997  TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1052

Query: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 1053 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1111

Query: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 1112 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1166

Query: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 1167 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1226

Query: 592  SEDAGVIC 599
             EDAGVIC
Sbjct: 1227 REDAGVIC 1234



 Score =  149 bits (375), Expect = 1e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 888  ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 947

Query: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 948  SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1007

Query: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 1008 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1067

Query: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 1068 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1122

Query: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 1123 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1182

Query: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 1183 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1238

Query: 494  LSLGFP 499
            LS   P
Sbjct: 1239 LSTPAP 1244



 Score =  112 bits (280), Expect = 1e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201


>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score =  329 bits (843), Expect = 8e-90
 Identities = 190/499 (38%), Positives = 247/499 (49%), Gaps = 50/499 (10%)

Query: 159  DWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGI 218
            D G    R+  +RL  GK   EG VE+   G WG++C+SHWD  DA V+C QL+ G   +
Sbjct: 572  DVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCG---V 628

Query: 219  AKQTPFS---GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS----- 270
            A  TP     G G   I+     C G E+++  C        +CP +  A+V CS     
Sbjct: 629  ALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ 688

Query: 271  -------FSHGPTFPII--------------RLAGGSSVHEGRVELYHAGQWGTVCDDQW 309
                    S GPT P I              RL  G     GRVE+YH G WGT+CDD W
Sbjct: 689  TLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSW 748

Query: 310  DDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNC 369
            D +DA V+CRQLG      A   A+FGEG+GP+ LDE++C G E  I QC    WG+ NC
Sbjct: 749  DLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNC 808

Query: 370  GHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLG 429
             HKEDAGV C+      +     + +  GRLEV+Y G WGTV     +E    VVCRQLG
Sbjct: 809  RHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLG 868

Query: 430  -FKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPG 488
                GK   A+  +  + P+W+D+V C        QC    W +   S  E+  I C   
Sbjct: 869  CADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC--- 925

Query: 489  GEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPAR 548
                       +RL +G     GRVE++  G WGT+CDD W   DA V+C+QLG     +
Sbjct: 926  --------DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK 977

Query: 549  ARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFG----- 603
            A   A FG+G GPI ++ VKC GNE SL DC  +  G   C H EDA V C         
Sbjct: 978  AFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTP 1037

Query: 604  -KKASGNSNKESLSSVCGL 621
             K  +G S+++S     G+
Sbjct: 1038 QKATTGRSSRQSSFIAVGI 1056



 Score =  299 bits (765), Expect = 9e-81
 Identities = 165/432 (38%), Positives = 218/432 (50%), Gaps = 12/432 (2%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           +RL  G+N+  G VEV     WGTVC++ W     SVIC+QL       A     S  G 
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 230 IPIYWSNVRCRGDEENILLCEKDIW-QGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288
             I+  +V CRG+E  +  C+ D W +   C  +  A VTCS         +RL  G ++
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLE---MRLTRGGNM 167

Query: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVR 348
             GR+E+   G+WGTVCDD ++   A VICRQL           + FGEGSGP+  D++ 
Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227

Query: 349 CTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQW 408
           C GNE ++  C    WG+HNC H EDAGV C+   D  +RL  G     GRLEV ++G+W
Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEW 287

Query: 409 GTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSR 467
           GT+CDDGW   +  V C+QLG      A    +  +  G IWLD VSC G E    QC  
Sbjct: 288 GTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKH 347

Query: 468 RQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDD 527
            +WG+H C+H ED  + C  G +         +RL  G ++  G VEV I    G +CD 
Sbjct: 348 HEWGKHYCNHNEDAGVTCSDGSD-------LELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 528 GWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRH 587
           GW  K+A V+CRQLG     +     Y         +    C GNE SL DC     G  
Sbjct: 401 GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460

Query: 588 NCRHSEDAGVIC 599
            C H E+A + C
Sbjct: 461 TCDHYEEAKITC 472



 Score =  274 bits (700), Expect = 3e-73
 Identities = 168/483 (34%), Positives = 226/483 (46%), Gaps = 49/483 (10%)

Query: 159 DWG--YCD--------CRHGS---VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDAS 205
           +WG  YC+        C  GS   +RLRGG +   GTVEV    + G VC   W   +A 
Sbjct: 349 EWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEAD 408

Query: 206 VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265
           V+C QL  G         +S +     +     C G+E ++  C+   W G  C     A
Sbjct: 409 VVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA 468

Query: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
            +TCS    P     RL GG     GRVE+ H   WG++CD  +    A V+CR+L    
Sbjct: 469 KITCSAHREP-----RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGT 523

Query: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDG 385
           +      A+FGEG+G +  +E +C G+E  +  CP +   E  C H  D GV C+  T+ 
Sbjct: 524 VVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE- 582

Query: 386 VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFE 442
            IRL  GK   EGR+E+   G WG++C+  W   + +V+C+QL  K G   S      F 
Sbjct: 583 -IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL--KCGVALSTPGGARFG 639

Query: 443 ESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRL------SL 496
           +  G IW     C+G E     C     G   C   +  S+ C  G +   L      SL
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVIC-SGNQSQTLSSCNSSSL 698

Query: 497 G-----------------FPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICR 539
           G                   +RL++G  +  GRVE++  G WGTICDD W   DA V+CR
Sbjct: 699 GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758

Query: 540 QLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           QLG      A   A+FGEG GPI +D +KC G E  +  C     G+ NCRH EDAGVIC
Sbjct: 759 QLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818

Query: 600 DYF 602
             F
Sbjct: 819 SEF 821



 Score =  266 bits (680), Expect = 6e-71
 Identities = 139/340 (40%), Positives = 192/340 (56%), Gaps = 11/340 (3%)

Query: 263 MAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 322
           + +A   + S G T   +RL  G +   GRVE+    +WGTVC++ W      VIC QLG
Sbjct: 34  LLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLG 93

Query: 323 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEH-NCGHKEDAGVSCTP 381
                KA   A    GSG + +D V C GNE ++  C    WG+H NC H++DAGV+C+ 
Sbjct: 94  CPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153

Query: 382 LTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQL--GFKYGKQASAN 439
            ++  +RL  G     GR+E+ ++G+WGTVCDD +   +  V+CRQL  G       S+N
Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSN 213

Query: 440 HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFP 499
            F E +GPIW DD+ C+G E+    C  + WG+H+C H ED  + C  G +   LSL   
Sbjct: 214 -FGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGAD---LSL--- 266

Query: 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGK 559
            RL+DG  +  GR+EV   G+WGTICDDGW   DAAV C+QLG      A       +G 
Sbjct: 267 -RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325

Query: 560 GPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           G I +D+V C G+E ++  C   + G+H C H+EDAGV C
Sbjct: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTC 365



 Score =  232 bits (591), Expect = 1e-60
 Identities = 164/540 (30%), Positives = 228/540 (42%), Gaps = 51/540 (9%)

Query: 160 WGYCDCRHG-------------SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASV 206
           WG  +C H              S+RL  G  E  G +EV   G WGT+C   WD  DA+V
Sbjct: 243 WGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302

Query: 207 ICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAA 266
            C QL       A     +  G   I+  +V C+G E  +  C+   W    C     A 
Sbjct: 303 ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362

Query: 267 VTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           VTCS         +RL GG S   G VE+      G VCD  W   +A+V+CRQLG    
Sbjct: 363 VTCSDGSDLE---LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV 386
            K  +Q Y    +    L    C GNE S+  C    WG   C H E+A ++C+   +  
Sbjct: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP- 478

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFEE 443
            RL GG     GR+EV +   WG++CD  ++     V+CR+L  + G   S     HF E
Sbjct: 479 -RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCREL--QCGTVVSILGGAHFGE 535

Query: 444 STGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLM 503
             G IW ++  C G E+    C         CSH  DV + C         S    +RL+
Sbjct: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC---------SRYTEIRLV 586

Query: 504 DGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIH 563
           +G+   EGRVE+   G WG++C+  W  +DA V+C+QL           A FG+G G I 
Sbjct: 587 NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646

Query: 564 VDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSV----- 618
                CTG E+ + DC    +G   C   + A VIC     +   + N  SL        
Sbjct: 647 RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706

Query: 619 --CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676
               +  +   Q R++ G     G    +V +  + S G        T+    W L+ AH
Sbjct: 707 EESAVACIESGQLRLVNGGGRCAG----RVEIYHEGSWG--------TICDDSWDLSDAH 754


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score =  329 bits (843), Expect = 8e-90
 Identities = 190/499 (38%), Positives = 247/499 (49%), Gaps = 50/499 (10%)

Query: 159  DWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGI 218
            D G    R+  +RL  GK   EG VE+   G WG++C+SHWD  DA V+C QL+ G   +
Sbjct: 572  DVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCG---V 628

Query: 219  AKQTPFS---GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS----- 270
            A  TP     G G   I+     C G E+++  C        +CP +  A+V CS     
Sbjct: 629  ALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQ 688

Query: 271  -------FSHGPTFPII--------------RLAGGSSVHEGRVELYHAGQWGTVCDDQW 309
                    S GPT P I              RL  G     GRVE+YH G WGT+CDD W
Sbjct: 689  TLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSW 748

Query: 310  DDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNC 369
            D +DA V+CRQLG      A   A+FGEG+GP+ LDE++C G E  I QC    WG+ NC
Sbjct: 749  DLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNC 808

Query: 370  GHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLG 429
             HKEDAGV C+      +     + +  GRLEV+Y G WGTV     +E    VVCRQLG
Sbjct: 809  RHKEDAGVICSEFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLG 868

Query: 430  -FKYGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPG 488
                GK   A+  +  + P+W+D+V C        QC    W +   S  E+  I C   
Sbjct: 869  CADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC--- 925

Query: 489  GEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPAR 548
                       +RL +G     GRVE++  G WGT+CDD W   DA V+C+QLG     +
Sbjct: 926  --------DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK 977

Query: 549  ARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFG----- 603
            A   A FG+G GPI ++ VKC GNE SL DC  +  G   C H EDA V C         
Sbjct: 978  AFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTP 1037

Query: 604  -KKASGNSNKESLSSVCGL 621
             K  +G S+++S     G+
Sbjct: 1038 QKATTGRSSRQSSFIAVGI 1056



 Score =  299 bits (765), Expect = 9e-81
 Identities = 165/432 (38%), Positives = 218/432 (50%), Gaps = 12/432 (2%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           +RL  G+N+  G VEV     WGTVC++ W     SVIC+QL       A     S  G 
Sbjct: 51  LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 230 IPIYWSNVRCRGDEENILLCEKDIW-QGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288
             I+  +V CRG+E  +  C+ D W +   C  +  A VTCS         +RL  G ++
Sbjct: 111 GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLE---MRLTRGGNM 167

Query: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVR 348
             GR+E+   G+WGTVCDD ++   A VICRQL           + FGEGSGP+  D++ 
Sbjct: 168 CSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLI 227

Query: 349 CTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQW 408
           C GNE ++  C    WG+HNC H EDAGV C+   D  +RL  G     GRLEV ++G+W
Sbjct: 228 CNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEW 287

Query: 409 GTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSR 467
           GT+CDDGW   +  V C+QLG      A    +  +  G IWLD VSC G E    QC  
Sbjct: 288 GTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKH 347

Query: 468 RQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDD 527
            +WG+H C+H ED  + C  G +         +RL  G ++  G VEV I    G +CD 
Sbjct: 348 HEWGKHYCNHNEDAGVTCSDGSD-------LELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 528 GWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRH 587
           GW  K+A V+CRQLG     +     Y         +    C GNE SL DC     G  
Sbjct: 401 GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460

Query: 588 NCRHSEDAGVIC 599
            C H E+A + C
Sbjct: 461 TCDHYEEAKITC 472



 Score =  274 bits (700), Expect = 3e-73
 Identities = 168/483 (34%), Positives = 226/483 (46%), Gaps = 49/483 (10%)

Query: 159 DWG--YCD--------CRHGS---VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDAS 205
           +WG  YC+        C  GS   +RLRGG +   GTVEV    + G VC   W   +A 
Sbjct: 349 EWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEAD 408

Query: 206 VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265
           V+C QL  G         +S +     +     C G+E ++  C+   W G  C     A
Sbjct: 409 VVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEA 468

Query: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
            +TCS    P     RL GG     GRVE+ H   WG++CD  +    A V+CR+L    
Sbjct: 469 KITCSAHREP-----RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGT 523

Query: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDG 385
           +      A+FGEG+G +  +E +C G+E  +  CP +   E  C H  D GV C+  T+ 
Sbjct: 524 VVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE- 582

Query: 386 VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFE 442
            IRL  GK   EGR+E+   G WG++C+  W   + +V+C+QL  K G   S      F 
Sbjct: 583 -IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQL--KCGVALSTPGGARFG 639

Query: 443 ESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRL------SL 496
           +  G IW     C+G E     C     G   C   +  S+ C  G +   L      SL
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVIC-SGNQSQTLSSCNSSSL 698

Query: 497 G-----------------FPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICR 539
           G                   +RL++G  +  GRVE++  G WGTICDD W   DA V+CR
Sbjct: 699 GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758

Query: 540 QLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           QLG      A   A+FGEG GPI +D +KC G E  +  C     G+ NCRH EDAGVIC
Sbjct: 759 QLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818

Query: 600 DYF 602
             F
Sbjct: 819 SEF 821



 Score =  266 bits (680), Expect = 6e-71
 Identities = 139/340 (40%), Positives = 192/340 (56%), Gaps = 11/340 (3%)

Query: 263 MAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 322
           + +A   + S G T   +RL  G +   GRVE+    +WGTVC++ W      VIC QLG
Sbjct: 34  LLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLG 93

Query: 323 LSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEH-NCGHKEDAGVSCTP 381
                KA   A    GSG + +D V C GNE ++  C    WG+H NC H++DAGV+C+ 
Sbjct: 94  CPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSD 153

Query: 382 LTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQL--GFKYGKQASAN 439
            ++  +RL  G     GR+E+ ++G+WGTVCDD +   +  V+CRQL  G       S+N
Sbjct: 154 GSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSN 213

Query: 440 HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFP 499
            F E +GPIW DD+ C+G E+    C  + WG+H+C H ED  + C  G +   LSL   
Sbjct: 214 -FGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGAD---LSL--- 266

Query: 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGK 559
            RL+DG  +  GR+EV   G+WGTICDDGW   DAAV C+QLG      A       +G 
Sbjct: 267 -RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGF 325

Query: 560 GPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           G I +D+V C G+E ++  C   + G+H C H+EDAGV C
Sbjct: 326 GHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTC 365



 Score =  232 bits (591), Expect = 1e-60
 Identities = 164/540 (30%), Positives = 228/540 (42%), Gaps = 51/540 (9%)

Query: 160 WGYCDCRHG-------------SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASV 206
           WG  +C H              S+RL  G  E  G +EV   G WGT+C   WD  DA+V
Sbjct: 243 WGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302

Query: 207 ICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAA 266
            C QL       A     +  G   I+  +V C+G E  +  C+   W    C     A 
Sbjct: 303 ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362

Query: 267 VTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
           VTCS         +RL GG S   G VE+      G VCD  W   +A+V+CRQLG    
Sbjct: 363 VTCSDGSDLE---LRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV 386
            K  +Q Y    +    L    C GNE S+  C    WG   C H E+A ++C+   +  
Sbjct: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP- 478

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFEE 443
            RL GG     GR+EV +   WG++CD  ++     V+CR+L  + G   S     HF E
Sbjct: 479 -RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCREL--QCGTVVSILGGAHFGE 535

Query: 444 STGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLM 503
             G IW ++  C G E+    C         CSH  DV + C         S    +RL+
Sbjct: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC---------SRYTEIRLV 586

Query: 504 DGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIH 563
           +G+   EGRVE+   G WG++C+  W  +DA V+C+QL           A FG+G G I 
Sbjct: 587 NGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIW 646

Query: 564 VDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSV----- 618
                CTG E+ + DC    +G   C   + A VIC     +   + N  SL        
Sbjct: 647 RHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIP 706

Query: 619 --CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676
               +  +   Q R++ G     G    +V +  + S G        T+    W L+ AH
Sbjct: 707 EESAVACIESGQLRLVNGGGRCAG----RVEIYHEGSWG--------TICDDSWDLSDAH 754


>gi|18152779 scavenger receptor cysteine rich domain containing,
           group B (4 domains) [Homo sapiens]
          Length = 575

 Score =  328 bits (842), Expect = 1e-89
 Identities = 192/518 (37%), Positives = 245/518 (47%), Gaps = 91/518 (17%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS---G 226
           +RL GG +   G +EV   G WG+VC   WD  DA+V+C QL   G G+A   P     G
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQL---GCGLALPVPRPLAFG 114

Query: 227 LGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC----------------- 269
            G  PI   NV CRG E  +  C    W    C      AV C                 
Sbjct: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174

Query: 270 ----SFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
               +  +G +   +RL GG+++ +GRVE+ H+G WGTVCDD W   DA V+CRQLG   
Sbjct: 175 APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGA 234

Query: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
              A   A+FG G+G ++LD V C G E  +  C    WG HNCGH EDAG  C  L   
Sbjct: 235 AMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPP 294

Query: 383 -----------------TD----------------------------GVIRLAGGKGSHE 397
                            TD                            G +RL GG G   
Sbjct: 295 TLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCR 354

Query: 398 GRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASA-NHFEESTGPIWLDDVSCS 456
           GR+EV + G WGTVCDD W   +  V CR+ G      A+   HF    GP+ LD+V C+
Sbjct: 355 GRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCA 414

Query: 457 GKETRFLQCSRRQWGRHDCSHREDVSIAC-----------YPGGEGHRLSLGFP----VR 501
           G E R   C    WG+H+C H ED    C             G E  R+    P    +R
Sbjct: 415 GTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLR 474

Query: 502 LMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGP 561
           L++G ++ EGRVE+++  +WGT+CDD W  + A V+CRQLG      A   A+FG G+GP
Sbjct: 475 LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534

Query: 562 IHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           I +DNVKC G E +L  C       HNC HSEDA V+C
Sbjct: 535 ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  266 bits (681), Expect = 5e-71
 Identities = 148/392 (37%), Positives = 182/392 (46%), Gaps = 72/392 (18%)

Query: 277 FPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFG 336
           F  +RL GG S   GR+E+ H G WG+VCDD WD  DA V+CRQLG            FG
Sbjct: 55  FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114

Query: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL-------------- 382
           +G GP++LD V C G E ++ +C    WG HNC H ED  V C                 
Sbjct: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174

Query: 383 ----------TDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKY 432
                     ++G +RL GG    +GR+E+ + G WGTVCDD W   +  VVCRQLG   
Sbjct: 175 APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGA 234

Query: 433 GKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEG 491
              A+ N  F   TG I LD+V C G E R   C    WG H+C H ED    C   G G
Sbjct: 235 AMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC--AGLG 292

Query: 492 HRLSLGFP-------------------------------------------VRLMDGENK 508
                  P                                           +RL+ G   
Sbjct: 293 PPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGP 352

Query: 509 KEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARART-MAYFGEGKGPIHVDNV 567
             GRVEV   G WGT+CDD W   DA V CR+ G  GPA   T + +FG G+GP+ +DNV
Sbjct: 353 CRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC-GPALGATGLGHFGYGRGPVLLDNV 411

Query: 568 KCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
            C G E  L+DC     G+HNC H EDAG +C
Sbjct: 412 GCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443



 Score =  253 bits (647), Expect = 4e-67
 Identities = 148/388 (38%), Positives = 177/388 (45%), Gaps = 68/388 (17%)

Query: 168 GSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGL 227
           GSVRL GG N  +G VE+  SG+WGTVC   W   DA+V+C QL  G    A    F G 
Sbjct: 187 GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY 246

Query: 228 GLIPIYWSNVRCRGDEENILLCEKDIW--------------------------------- 254
           G   I   NV C G E  +  C+   W                                 
Sbjct: 247 GTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATRE 306

Query: 255 ---------QGGVCPQ---KMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWG 302
                      GV PQ   + A   T +++ G     +RL GG     GRVE+ HAG WG
Sbjct: 307 DWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWG 366

Query: 303 TVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKS 362
           TVCDD WD ADA V CR+ G      A    +FG G GPV+LD V C G E  +  C   
Sbjct: 367 TVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHL 426

Query: 363 SWGEHNCGHKEDAGVSC---------------------TPL-TDGVIRLAGGKGSHEGRL 400
            WG+HNCGH EDAG  C                     TP   DG +RL  G    EGR+
Sbjct: 427 GWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRV 486

Query: 401 EVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKE 459
           E+Y   +WGTVCDD W      V+CRQLG      A    HF    GPI LD+V C G+E
Sbjct: 487 ELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEE 546

Query: 460 TRFLQCSRRQWGRHDCSHREDVSIACYP 487
           +  L CS  +W  H+C H ED S+ C P
Sbjct: 547 SALLLCSHIRWDAHNCDHSEDASVLCQP 574



 Score =  188 bits (478), Expect = 2e-47
 Identities = 104/247 (42%), Positives = 126/247 (51%), Gaps = 28/247 (11%)

Query: 380 TPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN 439
           TPL    +RL GG     GRLEV + G WG+VCDD W  ++  VVCRQLG          
Sbjct: 51  TPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRP 110

Query: 440 -HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC------------- 485
             F +  GPI LD+V C G+E    +C  R WG H+C H EDV++ C             
Sbjct: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM 170

Query: 486 ---------YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAV 536
                     P G+         VRL+ G N  +GRVE+  +G WGT+CDD W   DAAV
Sbjct: 171 LTSRAPPTTLPNGKSEG-----SVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAV 225

Query: 537 ICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAG 596
           +CRQLG      A T A+FG G G I +DNV C G E  LA C     G HNC H EDAG
Sbjct: 226 VCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAG 285

Query: 597 VICDYFG 603
            +C   G
Sbjct: 286 ALCAGLG 292



 Score =  154 bits (390), Expect = 3e-37
 Identities = 90/235 (38%), Positives = 112/235 (47%), Gaps = 19/235 (8%)

Query: 166 RHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS 225
           + G +RL GG     G VEV  +G WGTVC   WD +DA V C +   G    A      
Sbjct: 340 KSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHF 399

Query: 226 GLGLIPIYWSNVRCRGDEENILLCEKDIW----------QGGVC--PQKMAAAVTCSFSH 273
           G G  P+   NV C G E  +  C    W           G +C  P+++   V    S 
Sbjct: 400 GYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSE 459

Query: 274 GPTFPI-------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
               P        +RL  G+   EGRVELY   +WGTVCDD WD   A V+CRQLG    
Sbjct: 460 TTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQA 519

Query: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP 381
             A  +A+FG G GP++LD V+C G E ++  C    W  HNC H EDA V C P
Sbjct: 520 LAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQP 574


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score =  306 bits (785), Expect = 4e-83
 Identities = 178/489 (36%), Positives = 243/489 (49%), Gaps = 41/489 (8%)

Query: 166  RHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS 225
            R+  VRL  GK++ +G VE+   G WG++C +HWD  DA V+C QL  G         + 
Sbjct: 896  RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYI 955

Query: 226  GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFS-HGPTFPII---- 280
            G   + ++     C G+E  +  C+  +     C      +V C+ S   P FP +    
Sbjct: 956  GERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVS 1015

Query: 281  ---------------------RLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR 319
                                 RL  G S   GRVE+YH G WGT+CDD WD +DA V+C+
Sbjct: 1016 DPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQ 1075

Query: 320  QLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379
            +LG      A   A+FGEGSGP+ LD++ CTG E  + QCP   WG+H+C HKEDAGV C
Sbjct: 1076 KLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135

Query: 380  TPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF-KYGKQASA 438
            +  T   +       S  GRLEV+Y G WG+V     T     +VCRQLG  + G  + A
Sbjct: 1136 SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLA 1195

Query: 439  NHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGF 498
               +  +G +W+DD+ C        QC    W R   S  E+  I C             
Sbjct: 1196 PLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCED----------- 1244

Query: 499  PVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEG 558
             +R+  G+ +  GRVE++  G WGT+CDD W   +A V+C+QLG      A   A FG+G
Sbjct: 1245 RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQG 1304

Query: 559  KGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKK---ASGNSNKESL 615
             G I +D+++C GNE  L DC  +  G+ +C H EDAGV C     K   AS       L
Sbjct: 1305 TGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALIL 1364

Query: 616  SSVCGLRLL 624
            SS+ GL LL
Sbjct: 1365 SSIFGLLLL 1373



 Score =  289 bits (740), Expect = 7e-78
 Identities = 160/437 (36%), Positives = 218/437 (49%), Gaps = 23/437 (5%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           +RL  G N   G VEV     W T+C  +W +  A V+C QL         +        
Sbjct: 369 LRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEA 428

Query: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
             I+ +++ C G+E  +  C  D      C ++  A V CS         +RL G  S  
Sbjct: 429 RDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLD---LRLVGAHSPC 485

Query: 290 EGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRC 349
            GR+E+ + G+WGTVC D+W   +A V+C+QLG       +   YF E SGP+ LD+V C
Sbjct: 486 YGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSC 545

Query: 350 TGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWG 409
            GNE +I  C  S WG+HNC H+ED  V+C+      +RL GG     GRLEVY++G+WG
Sbjct: 546 IGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQGRWG 605

Query: 410 TVCDDGWTELNTYVVCRQL-------GFKYGKQASANHFEESTGPIWLDDVSCSGKETRF 462
           TVCDDGW      VVC QL       G   G  ++        G IWLDDVSC G E+  
Sbjct: 606 TVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAST------GYGKIWLDDVSCDGDESDL 659

Query: 463 LQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWG 522
             C    WG +DCSH EDV + C    +         +RL+ G ++  G+VEV + G  G
Sbjct: 660 WSCRNSGWGNNDCSHSEDVGVICSDASD-------MELRLVGGSSRCAGKVEVNVQGAVG 712

Query: 523 TICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQ 582
            +C +GW    A V+CRQL      R     +F E    I + N  CTG E SL DCI+ 
Sbjct: 713 ILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRW 772

Query: 583 DIGRHNCRHSEDAGVIC 599
           +  +  C  + +A +IC
Sbjct: 773 EWKQTACHLNMEASLIC 789



 Score =  280 bits (715), Expect = 5e-75
 Identities = 159/471 (33%), Positives = 226/471 (47%), Gaps = 27/471 (5%)

Query: 159 DWGYCDCRHGS-------------VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDAS 205
           +WG  +C HG              +RL  G N   G VEV     WGT+C   W+ + A+
Sbjct: 131 EWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAA 190

Query: 206 VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265
           V+C QL      I+     S   L PI+  ++ C+G+E  +  C    W    C      
Sbjct: 191 VVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV 250

Query: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
            +TC  S       +RL GG++   GRVEL   G+WGTVC  +W++A A+V+C+QLG   
Sbjct: 251 TLTCYDSSDLE---LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT 307

Query: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDG 385
                   +   GS  V LD V C+GNE  +  C  S     +C H+ D  V C+   D 
Sbjct: 308 ALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL 367

Query: 386 VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEEST 445
            +RLA G  +  GR+EV    QW T+CD  W      VVC+QLG  +    S      + 
Sbjct: 368 ELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNE 427

Query: 446 G-PIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMD 504
              IW++ +SC+G E+    C+     +  C  R D  + C    +         +RL+ 
Sbjct: 428 ARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKAD-------LDLRLVG 480

Query: 505 GENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHV 564
             +   GR+EV   G+WGT+C D W+ ++AAV+C+QLG   P     M YF E  GPI +
Sbjct: 481 AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWL 540

Query: 565 DNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICD---YFGKKASGNSNK 612
           D+V C GNE ++ DC     G+HNC H ED  V C     +G +  G SN+
Sbjct: 541 DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNR 591



 Score =  268 bits (684), Expect = 2e-71
 Identities = 157/479 (32%), Positives = 220/479 (45%), Gaps = 43/479 (8%)

Query: 160  WGYCDCRHGS-------------VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASV 206
            WG  DC H               +RL GG +   G VEV   G  G +C++ W  + A V
Sbjct: 667  WGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEV 726

Query: 207  ICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAA 266
            +C QL+ G      + P      + I  SN  C G E ++  C +  W+   C   M A+
Sbjct: 727  VCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEAS 786

Query: 267  VTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
            + CS    P     RL G      GRVE+ HA  W +VCD  +    A V+CR+L     
Sbjct: 787  LICSAHRQP-----RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDA 841

Query: 327  AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV 386
                   +FG+G+G    ++ +C G+E  +  CP     E  C H  + GV C+  TD  
Sbjct: 842  ISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD-- 899

Query: 387  IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYG-KQASANHFEEST 445
            +RL  GK   +G++E+   G WG++CD  W   +  V+CRQL            +  E +
Sbjct: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959

Query: 446  GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC-------------------- 485
              +W     C G E+    C     G   C H   VS+ C                    
Sbjct: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019

Query: 486  --YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGY 543
               P G          +RL+DG+++  GRVE++ +G WGTICDDGW   DA V+C++LG 
Sbjct: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079

Query: 544  KGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYF 602
                 A   A+FGEG GPI +D++ CTG E  L  C  +  G+H+CRH EDAGVIC  F
Sbjct: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEF 1138



 Score =  267 bits (682), Expect = 4e-71
 Identities = 151/439 (34%), Positives = 209/439 (47%), Gaps = 27/439 (6%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLG--------GKGIAKQ 221
           +RL  G     GTVEV   G WGTVC   W+ + ++V+C QL           G+ + + 
Sbjct: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRH 107

Query: 222 TPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIR 281
                     I+  +V C G+E  +  C+   W    C       V C   +G     +R
Sbjct: 108 G--------KIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---YGEANLGLR 156

Query: 282 LAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGP 341
           L  G++   GRVE+    +WGT+CDD W+   A V+CRQLG      +           P
Sbjct: 157 LVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRP 216

Query: 342 VMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLE 401
           + LD++ C GNEL++  C    WG H+C H ED  ++C   +D  +RL GG     GR+E
Sbjct: 217 IWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVE 276

Query: 402 VYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQ-ASANHFEESTGPIWLDDVSCSGKET 460
           +  +G+WGTVC   W      VVC+QLG       A   H +  +  +WLD VSCSG E+
Sbjct: 277 LKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNES 336

Query: 461 RFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQ 520
               C        DC H+ DVS+ C  G +         +RL DG N   GRVEV I+ Q
Sbjct: 337 FLWDCRHSGTVNFDCLHQNDVSVICSDGAD-------LELRLADGSNNCSGRVEVRIHEQ 389

Query: 521 WGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCI 580
           W TICD  W ++ A V+C+QLG          A        I ++++ CTGNE +L DC 
Sbjct: 390 WWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCT 449

Query: 581 KQDIGRHNCRHSEDAGVIC 599
                +  C    DAGVIC
Sbjct: 450 YDGKAKRTCFRRSDAGVIC 468



 Score =  252 bits (644), Expect = 9e-67
 Identities = 137/368 (37%), Positives = 183/368 (49%), Gaps = 22/368 (5%)

Query: 259 CPQKM-AAAVTCSFSHGPTFPI---------IRLAGGSSVHEGRVELYHAGQWGTVCDDQ 308
           C Q + +A VTC       F I         +RL  G     G VE+   GQWGTVCDD 
Sbjct: 17  CHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDG 76

Query: 309 WDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHN 368
           W+   + V+C+QLG       +         G + LD+V C GNE ++ +C    WG HN
Sbjct: 77  WNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHN 136

Query: 369 CGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQL 428
           C H ED GV+C    +  +RL  G  S  GR+EV ++ +WGT+CDDGW      VVCRQL
Sbjct: 137 CYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQL 196

Query: 429 GFKYGKQAS-ANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYP 487
           G      +S   +      PIWLDD+ C G E     C  R WG HDCSH EDV++ CY 
Sbjct: 197 GCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYD 256

Query: 488 GGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPA 547
             +         +RL+ G N+  GRVE+ I G+WGT+C   W +  A V+C+QLG     
Sbjct: 257 SSD-------LELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTAL 309

Query: 548 RARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC----DYFG 603
               + +   G   + +D V C+GNE  L DC        +C H  D  VIC    D   
Sbjct: 310 HFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLEL 369

Query: 604 KKASGNSN 611
           + A G++N
Sbjct: 370 RLADGSNN 377



 Score =  244 bits (622), Expect = 3e-64
 Identities = 154/466 (33%), Positives = 212/466 (45%), Gaps = 24/466 (5%)

Query: 142 DGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDD 201
           DG  +  CF     G +     D     +RL G  +   G +EV   G WGTVC   W  
Sbjct: 451 DGKAKRTCFRRSDAGVICSDKADL---DLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWST 507

Query: 202 SDASVICHQLQLGGK----GIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGG 257
            +A+V+C QL  G      G+      SG    PI+  +V C G+E NI  CE   W   
Sbjct: 508 RNAAVVCKQLGCGKPMHVFGMTYFKEASG----PIWLDDVSCIGNESNIWDCEHSGWGKH 563

Query: 258 VCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVI 317
            C  +    VTCS   G     +RL GGS+   GR+E+Y  G+WGTVCDD W+   A V+
Sbjct: 564 NCVHREDVIVTCS---GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVV 620

Query: 318 CRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGV 377
           C QL                G G + LD+V C G+E  +  C  S WG ++C H ED GV
Sbjct: 621 CSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGV 680

Query: 378 SCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS 437
            C+  +D  +RL GG     G++EV  +G  G +C +GW      VVCRQL      + S
Sbjct: 681 ICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVS 740

Query: 438 AN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSL 496
              HF E T  I + +  C+G E     C R +W +  C    + S+ C      HR   
Sbjct: 741 REPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLIC----SAHRQP- 795

Query: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556
               RL+  +    GRVEV     W ++CD  ++   A V+CR+L            +FG
Sbjct: 796 ----RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFG 851

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYF 602
           +G G    +  +C G+E  LA C         C HS + GV+C  +
Sbjct: 852 KGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY 897



 Score =  160 bits (406), Expect = 4e-39
 Identities = 86/235 (36%), Positives = 123/235 (52%), Gaps = 22/235 (9%)

Query: 160  WGYCDCRH-----------GSVRLRGGKNEFE---GTVEVYASGVWGTVCSSHWDDSDAS 205
            WG  DCRH            ++RL   + E E   G +EV+ +G WG+V   +   + A 
Sbjct: 1120 WGQHDCRHKEDAGVICSEFTALRLY-SETETESCAGRLEVFYNGTWGSVGRRNITTAIAG 1178

Query: 206  VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265
            ++C QL  G  G+    P S  G   ++  +++C     +I  C    W+  +       
Sbjct: 1179 IVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEET 1238

Query: 266  AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
             +TC          IR+ GG +   GRVE++HAG WGTVCDD WD A+AEV+C+QLG   
Sbjct: 1239 WITCE-------DRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291

Query: 326  IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT 380
               A   A FG+G+G + LD++RC GNE  +  C    WG+ +CGHKEDAGV C+
Sbjct: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  284 bits (727), Expect = 2e-76
 Identities = 153/371 (41%), Positives = 194/371 (52%), Gaps = 52/371 (14%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGS 339
           +RL  G     GR+E++H G+WGTVCDD WD  DA V CR+LG  G   A   A FG G+
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257

Query: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGR 399
           GPV +D+V C G E ++  CP+S WG  NC H EDAG+ CT      +RLA G     GR
Sbjct: 258 GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR-LRLADGPHGCAGR 316

Query: 400 LEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGK 458
           LEV++ G+WG+VCDD W   +  V CR+LG      A     F E +GPI LDD+ C G 
Sbjct: 317 LEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGN 376

Query: 459 ETRFLQCSRRQWGRHDCSHREDVSIAC--------------------------------- 485
           ET    C  R WG+HDC HRED    C                                 
Sbjct: 377 ETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMT 436

Query: 486 --YPGGEGHRLSLGFP--------------VRLMDGENKKEGRVEVFINGQWGTICDDGW 529
              PG  G       P              +RL+ G +K  GR+EV+ + +WGT+CDD W
Sbjct: 437 SQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSW 496

Query: 530 TDKDAAVICRQLGYKGPARARTMA-YFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHN 588
             +D+AV+CR+LG  GP +    A  FG G GPI +D+V C G E SL+DC     G+HN
Sbjct: 497 DMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHN 556

Query: 589 CRHSEDAGVIC 599
           C H+ED GV C
Sbjct: 557 CAHNEDVGVTC 567



 Score =  258 bits (659), Expect = 2e-68
 Identities = 141/378 (37%), Positives = 185/378 (48%), Gaps = 62/378 (16%)

Query: 166 RHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS 225
           R   +RL  G +   G +EV+  G WGTVC   WD  DA+V C +L  GG   A      
Sbjct: 194 RQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARF 253

Query: 226 GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGG 285
           G G  P++  +V C G E+ +  C +  W    C     A + C+   GP  P +RLA G
Sbjct: 254 GPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCT---GPA-PRLRLADG 309

Query: 286 SSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLD 345
                GR+E++H G+WG+VCDD WD  DA V CR+LG  G   A   A+FGEGSGP++LD
Sbjct: 310 PHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILD 369

Query: 346 EVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------------------------- 379
           ++RC GNE ++  CP   WG+H+C H+EDAG  C                          
Sbjct: 370 DLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAAS 429

Query: 380 ---------TPLTDGV---------------------IRLAGGKGSHEGRLEVYYRGQWG 409
                     P T GV                     +RL  G     GRLEV++  +WG
Sbjct: 430 RPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWG 489

Query: 410 TVCDDGWTELNTYVVCRQLGFKYGKQ--ASANHFEESTGPIWLDDVSCSGKETRFLQCSR 467
           TVCDD W   ++ VVCR+LG    +Q   +A  F    GPIWLDDV C G E     C  
Sbjct: 490 TVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPA 549

Query: 468 RQWGRHDCSHREDVSIAC 485
             WG+H+C+H EDV + C
Sbjct: 550 APWGKHNCAHNEDVGVTC 567



 Score =  250 bits (639), Expect = 4e-66
 Identities = 153/443 (34%), Positives = 202/443 (45%), Gaps = 70/443 (15%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           +RL  G +   G +EV+  G WGTVC   WD  DA+V C QL  GG   A    F G G 
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
            P++ S + CRG+E  + LC    W+  +C  +  A V C+              G  V 
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCA--------------GQRVA 125

Query: 290 EGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRC 349
             R             DD     D                W          P +L E+  
Sbjct: 126 NSR-------------DDSTSPLD-------------GAPW----------PGLLLELSP 149

Query: 350 TGNELSIEQCPKSSWGEHNCGHKED------AGVSCTPLTDGV-----IRLAGGKGSHEG 398
           +  E  +   P+ +    N   K+              LT G      +RL  G     G
Sbjct: 150 STEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAG 209

Query: 399 RLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSG 457
           RLEV++ G+WGTVCDDGW   +  V CR+LG      A     F    GP+W+DDV C G
Sbjct: 210 RLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGG 269

Query: 458 KETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFI 517
            E     C R  WGR +C H ED  + C   G   RL      RL DG +   GR+EV+ 
Sbjct: 270 GEQALRDCPRSPWGRSNCDHSEDAGLVC--TGPAPRL------RLADGPHGCAGRLEVWH 321

Query: 518 NGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLA 577
            G+WG++CDD W  +DAAV CR+LG  G   A   A+FGEG GPI +D+++C GNE +L 
Sbjct: 322 GGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALR 381

Query: 578 DCIKQDIGRHNCRHSEDAGVICD 600
            C  +  G+H+C H EDAG +CD
Sbjct: 382 FCPARPWGQHDCHHREDAGAVCD 404



 Score =  162 bits (409), Expect = 2e-39
 Identities = 125/412 (30%), Positives = 166/412 (40%), Gaps = 97/412 (23%)

Query: 48  PTQQRPPTTRPPPPLPRFPRPPRALPAQRPHA----LQAGHTPRPHPWGCPAGEPWVSVT 103
           P  ++  +TR P      PR  R      PH     L+  H  R   WG    + W  + 
Sbjct: 175 PRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGR---WGTVCDDGW-DLR 230

Query: 104 DFGAPCLRWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPW-----CFYGDAR--- 155
           D    C          E     + A   G R        GAG  W     C  G+     
Sbjct: 231 DAAVACR---------ELGCGGALAAPGGARFG-----PGAGPVWMDDVGCGGGEQALRD 276

Query: 156 -GKVDWGYCDCRHGS------------VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDS 202
             +  WG  +C H              +RL  G +   G +EV+  G WG+VC   WD  
Sbjct: 277 CPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLR 336

Query: 203 DASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIW-------- 254
           DA+V C +L  GG   A    F G G  PI   ++RCRG+E  +  C    W        
Sbjct: 337 DAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHR 396

Query: 255 --QGGVC--------------------PQKMA---------------------AAVTCSF 271
              G VC                    P++ A                     A+ T  +
Sbjct: 397 EDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLW 456

Query: 272 SHGPTF--PIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329
             GP    P +RL  G S   GR+E++H  +WGTVCDD WD  D+ V+CR+LG  G  + 
Sbjct: 457 EPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQP 516

Query: 330 WHQA-YFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT 380
              A  FG G+GP+ LD+V C G E S+  CP + WG+HNC H ED GV+CT
Sbjct: 517 DPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  124 bits (310), Expect = 5e-28
 Identities = 50/105 (47%), Positives = 72/105 (68%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGS 339
           +RLA G +   GR+E++HAG+WGTVCDD WD  DA V C +LG   +     + ++G G+
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTD 384
           GP+ LD++ C G+E S+  CP  +WG+HNC H+ED G++CT  TD
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTD 876



 Score =  108 bits (271), Expect = 2e-23
 Identities = 56/121 (46%), Positives = 74/121 (61%), Gaps = 3/121 (2%)

Query: 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGK 559
           +RL DG +   GR+EV+  G+WGT+CDDGW  +DAAV CRQLG  G   A   A+FGEG 
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 560 GPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVC 619
           GP+ +  + C GNE  L  C  +    H C H EDAGV+C   G++ + NS  +S S + 
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC--AGQRVA-NSRDDSTSPLD 136

Query: 620 G 620
           G
Sbjct: 137 G 137



 Score =  104 bits (260), Expect = 3e-22
 Identities = 50/103 (48%), Positives = 66/103 (64%), Gaps = 2/103 (1%)

Query: 498 FPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARART-MAYFG 556
           F VRL DG N+  GR+EV+  G+WGT+CDD W  +DA V C +LG  G  R R    ++G
Sbjct: 770 FRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGC-GKVRPRVGKTHYG 828

Query: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
            G GPI +D++ C G+E SL+DC     G+HNC H ED G+ C
Sbjct: 829 PGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871



 Score =  104 bits (259), Expect = 4e-22
 Identities = 45/100 (45%), Positives = 57/100 (57%), Gaps = 1/100 (1%)

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF-KYGKQASANHFEEST 445
           +RLA G     GRLEV++ G+WGTVCDD W   +  V C +LG  K   +    H+   T
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC 485
           GPIWLDD+ C G E     C    WG+H+C H EDV + C
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 34/101 (33%), Positives = 49/101 (48%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           VRL  G N   G +EV+ +G WGTVC  +WD  DA+V C +L  G           G G 
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS 270
            PI+  ++ C+G E ++  C    W    C  +    +TC+
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCT 872


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  243 bits (619), Expect = 7e-64
 Identities = 136/335 (40%), Positives = 180/335 (53%), Gaps = 28/335 (8%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG---LSGIAKAWHQAYFG 336
           +RL GG    EGRVE+   GQWGTVCDD WD  D  V+CR+LG    SG           
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPLTDGVIRL 389
           E    V++  V CTG E ++ QC +     ++C H EDAG SC       +P+ +GV RL
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPEGV-RL 140

Query: 390 AGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYG--KQASANHFEESTGP 447
           A G G  +GR+EV ++ QW TVC  GW+     VVCRQLG       Q   N       P
Sbjct: 141 ADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKP 200

Query: 448 IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGEN 507
           IWL  +SCSG+E     C    WG++ C+H ED  + C            F +RL+ G+N
Sbjct: 201 IWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECED---------PFDLRLVGGDN 251

Query: 508 KKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARA---RTMAYFGEGKGPIHV 564
              GR+EV   G WG++CDD W +K+  V+C+QLG  G + +   R    +G G G I +
Sbjct: 252 LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGC-GKSLSPSFRDRKCYGPGVGRIWL 310

Query: 565 DNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
           DNV+C+G E+SL  C  +  G H+C H ED  VIC
Sbjct: 311 DNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVIC 345



 Score =  228 bits (580), Expect = 2e-59
 Identities = 129/332 (38%), Positives = 171/332 (51%), Gaps = 26/332 (7%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           VRL GG +  EG VEV   G WGTVC   WD  D +V+C +L   G G A  TP SG+  
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCREL---GCGAASGTP-SGILY 79

Query: 230 IP-------IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPI--- 279
            P       +   +V C G E+ +  CE++  +   C     A  +C        P+   
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEG 137

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQA-YFGEG 338
           +RLA G    +GRVE+ H  QW TVC   W    A+V+CRQLG         +      G
Sbjct: 138 VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 339 SGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEG 398
             P+ L ++ C+G E +++ CP   WG++ C H ED  V C    D  +RL GG     G
Sbjct: 198 RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFD--LRLVGGDNLCSG 255

Query: 399 RLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANH-----FEESTGPIWLDDV 453
           RLEV ++G WG+VCDD W E    VVC+QLG   GK  S +      +    G IWLD+V
Sbjct: 256 RLEVLHKGVWGSVCDDNWGEKEDQVVCKQLG--CGKSLSPSFRDRKCYGPGVGRIWLDNV 313

Query: 454 SCSGKETRFLQCSRRQWGRHDCSHREDVSIAC 485
            CSG+E    QC  R WG HDC+H+EDV++ C
Sbjct: 314 RCSGEEQSLEQCQHRFWGFHDCTHQEDVAVIC 345



 Score =  143 bits (361), Expect = 6e-34
 Identities = 87/234 (37%), Positives = 115/234 (49%), Gaps = 15/234 (6%)

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTG 446
           +RL GG    EGR+EV  +GQWGTVCDDGW   +  V+CR+LG        +    E   
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 447 P----IWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRL 502
                + +  VSC+G E    QC + +   +DCSH ED   +C    E     +   VRL
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCEQEEV--YDCSHDEDAGASC-ENPESSFSPVPEGVRL 140

Query: 503 MDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPA----RARTMAYFGEG 558
            DG    +GRVEV    QW T+C  GW+ + A V+CRQLG         R    AY   G
Sbjct: 141 ADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAY---G 197

Query: 559 KGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC-DYFGKKASGNSN 611
           + PI +  + C+G E +L DC     G++ C H ED  V C D F  +  G  N
Sbjct: 198 RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDN 251



 Score =  140 bits (352), Expect = 7e-33
 Identities = 76/214 (35%), Positives = 107/214 (50%), Gaps = 8/214 (3%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIA-KQTPFSGLG 228
           VRL  G    +G VEV     W TVC + W    A V+C QL  G   +  K+      G
Sbjct: 138 VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSV 288
             PI+ S + C G E  +  C    W    C       V C          +RL GG ++
Sbjct: 198 RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFD-----LRLVGGDNL 252

Query: 289 HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLS-GIAKAWH-QAYFGEGSGPVMLDE 346
             GR+E+ H G WG+VCDD W + + +V+C+QLG    ++ ++  +  +G G G + LD 
Sbjct: 253 CSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDN 312

Query: 347 VRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT 380
           VRC+G E S+EQC    WG H+C H+ED  V C+
Sbjct: 313 VRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  228 bits (582), Expect = 1e-59
 Identities = 135/381 (35%), Positives = 177/381 (46%), Gaps = 61/381 (16%)

Query: 280 IRLAGGSSV-HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG 338
           +RL G  S   EGR+E+ H GQWGTVCDD +   +A V CRQLG        H A +G+G
Sbjct: 32  LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91

Query: 339 SGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP------LTDGVIRLAGG 392
            GP+ LD VRC G E S++QC  + WG  +C H ED GV C P      L++ V    G 
Sbjct: 92  EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151

Query: 393 KGSH--------------------EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKY 432
           +G                      EG +EV Y G W  VCD GWT  N+ VVC  LGF  
Sbjct: 152 QGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPS 211

Query: 433 GKQASANHFEE-----------------STGPIWLDDVSCSGKETRFLQCS-----RRQW 470
                ++++ +                 +    W+  V+C G E     C       R  
Sbjct: 212 EVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGK 271

Query: 471 GRHDCSHREDVSIACYPGGEGHRLSLGFP-----------VRLMDGENKKEGRVEVFING 519
            R  C       ++C   G   R     P           VRL  G    EGRVEV +N 
Sbjct: 272 LRPACPGGMHAVVSCV-AGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330

Query: 520 QWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579
           QWGT+CD  W    A+V+CRQLG+     A   A  G+G GPIH+  V+C G ER+L+DC
Sbjct: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390

Query: 580 IKQDIGRHNCRHSEDAGVICD 600
              +  ++ C+H  DA V C+
Sbjct: 391 PALEGSQNGCQHENDAAVRCN 411



 Score =  171 bits (433), Expect = 3e-42
 Identities = 145/492 (29%), Positives = 194/492 (39%), Gaps = 78/492 (15%)

Query: 180 EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRC 239
           EG +EV   G WGTVC  ++   +A+V C QL          +   G G  PI+  NVRC
Sbjct: 43  EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102

Query: 240 RGDEENILLCEKDIWQGGVCPQKMAAAVTC-------------SFSHGPTF--------- 277
            G E ++  C  + W    C       V C             S + GP           
Sbjct: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLK 162

Query: 278 PIIRLAGGSS-VHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG--------IAK 328
           PI+  A   S V EG VE+ + G W  VCD  W   ++ V+C  LG             K
Sbjct: 163 PILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRK 222

Query: 329 AWHQAYFGEGS--------GPVMLDEVRCTGNELSIEQC-----PKSSWGEHNCGHKEDA 375
            W        S            + +V C G E  +  C     P        C     A
Sbjct: 223 VWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHA 282

Query: 376 GVSCT-----------PLTDGV------IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTE 418
            VSC            P   G       +RL  G    EGR+EV    QWGTVCD  W  
Sbjct: 283 VVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNL 342

Query: 419 LNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSH 477
           ++  VVCRQLGF   ++A       +  GPI L +V C G E     C   +  ++ C H
Sbjct: 343 ISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQH 402

Query: 478 REDVSIACYPGGEGHRLSLGFPVRLMDGENKKEG--RVEVFING--QWGTICDDGWTDKD 533
             D ++ C     G +      VRL  G   +EG   V+V +NG  +WG++C + W   +
Sbjct: 403 ENDAAVRCNVPNMGFQNQ----VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTE 458

Query: 534 AAVICRQLGYKGPARARTMAYFGEG---KGPIHVDNVKCTGNERSLADCIKQDIGRHNCR 590
           A V CRQLG      A    +F  G      + +  V+C+G E +L  C  Q  G  +C 
Sbjct: 459 AMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC--QRHGPVHCS 516

Query: 591 HSED---AGVIC 599
           H      AGV C
Sbjct: 517 HGGGRFLAGVSC 528



 Score =  130 bits (328), Expect = 4e-30
 Identities = 86/223 (38%), Positives = 116/223 (52%), Gaps = 18/223 (8%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS---G 226
           VRLR G    EG VEV  +  WGTVC   W+   ASV+C QL   G G A++  F    G
Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQL---GFGSAREALFGARLG 367

Query: 227 LGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGS 286
            GL PI+ S VRCRG E  +  C         C  +  AAV C+  +      +RLAGG 
Sbjct: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGR 427

Query: 287 SVHEG----RVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG---S 339
              EG    +VE+    +WG+VC + W   +A V CRQLGL     A+ + +F  G   +
Sbjct: 428 IPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRA 487

Query: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGH---KEDAGVSC 379
             V++  VRC+G EL+++QC +   G  +C H   +  AGVSC
Sbjct: 488 QEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSC 528


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  211 bits (537), Expect = 2e-54
 Identities = 131/370 (35%), Positives = 178/370 (48%), Gaps = 51/370 (13%)

Query: 280 IRLAGGSSVH-EGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWH-QAYFGE 337
           +RLAG    H EGRVE+Y+ GQWGTVCDD +    A V+CR+LG    AK+W   + +G+
Sbjct: 58  LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVE-AKSWTASSSYGK 116

Query: 338 GSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP-----------LTDGV 386
           G GP+ LD + CTGNE ++  C  + WG  +C H ED GV C+            L + +
Sbjct: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176

Query: 387 ---------IRLAGGKGSH-------EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF 430
                    IR+     ++       EG +EV     W  +CD  WT  N+ VVC   GF
Sbjct: 177 ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236

Query: 431 K----YGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHD------CSHRED 480
                Y  +             W   + C+G E     C        D      C +   
Sbjct: 237 PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296

Query: 481 VSIACYPG------GEGHRLSLGFP----VRLMDGENKKEGRVEVFINGQWGTICDDGWT 530
             ++C PG      G         P    VRL  G    EGRVEV  NG+WGT+CDD W 
Sbjct: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWD 356

Query: 531 DKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCR 590
              A+V+CR+LG+     A T +  G+G GPIH++ ++CTGNE+S+ DC K +     C 
Sbjct: 357 LVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC-KFNAESQGCN 415

Query: 591 HSEDAGVICD 600
           H EDAGV C+
Sbjct: 416 HEEDAGVRCN 425



 Score =  194 bits (492), Expect = 4e-49
 Identities = 148/477 (31%), Positives = 200/477 (41%), Gaps = 80/477 (16%)

Query: 170 VRLRGGKNEF-EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           +RL G K +  EG VEVY  G WGTVC   +    A V+C +L          +   G G
Sbjct: 58  LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKG 117

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPI--------- 279
             PI+  N+ C G+E  +  C  + W    C       V CS    P F           
Sbjct: 118 EGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIE 177

Query: 280 --------IRLAG-------GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLS 324
                   IR+          + V EG VE+     W  +CD  W   ++ V+C   G  
Sbjct: 178 NLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237

Query: 325 G-----------IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC---PKSS---WGEH 367
           G            A    Q Y+     P  +D   CTG E  I  C   P+ S       
Sbjct: 238 GERTYNTKVYKMFASRRKQRYW-----PFSMD---CTGTEAHISSCKLGPQVSLDPMKNV 289

Query: 368 NCGHKEDAGVSCTP----LTDG-------------VIRLAGGKGSHEGRLEVYYRGQWGT 410
            C +   A VSC P      DG             ++RL GG    EGR+EV   G+WGT
Sbjct: 290 TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGT 349

Query: 411 VCDDGWTELNTYVVCRQLGFKYGKQA-SANHFEESTGPIWLDDVSCSGKETRFLQCSRRQ 469
           VCDD W  ++  VVCR+LGF   K+A + +   +  GPI L+++ C+G E   + C    
Sbjct: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409

Query: 470 WGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFI--NGQ--WGTIC 525
             +  C+H ED  + C     G +  L    RL  G N  EGRVEV +  NG   WG +C
Sbjct: 410 ESQ-GCNHEEDAGVRCNTPAMGLQKKL----RLNGGRNPYEGRVEVLVERNGSLVWGMVC 464

Query: 526 DDGWTDKDAAVICRQLGYKGPARARTMAYFGEG---KGPIHVDNVKCTGNERSLADC 579
              W   +A V+CRQLG    + A    ++  G      + +  VKC+G E SLA C
Sbjct: 465 GQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521



 Score =  179 bits (454), Expect = 1e-44
 Identities = 117/344 (34%), Positives = 161/344 (46%), Gaps = 46/344 (13%)

Query: 180 EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLI--PIYWS-N 236
           EG VEV     W  +C  HW   ++ V+C      G+       +          YW  +
Sbjct: 203 EGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFS 262

Query: 237 VRCRGDEENILLCEK------DIWQGGVCPQKMAAAVTCS----FS----------HGPT 276
           + C G E +I  C+       D  +   C   + A V+C     FS          + P 
Sbjct: 263 MDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPE 322

Query: 277 FPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFG 336
            P++RL GG+ + EGRVE+   G+WGTVCDD+WD   A V+CR+LG     +A   +  G
Sbjct: 323 QPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLG 382

Query: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV---IRLAGGK 393
           +G GP+ L+E++CTGNE SI  C K +     C H+EDAGV C     G+   +RL GG+
Sbjct: 383 QGIGPIHLNEIQCTGNEKSIIDC-KFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGR 441

Query: 394 GSHEGRLEVYYRGQ----WGTVCDDGWTELNTYVVCRQLGFKYGKQASAN----HFEEST 445
             +EGR+EV         WG VC   W  +   VVCRQLG  +   A       H + ++
Sbjct: 442 NPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNS 501

Query: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGG 489
             + +  V CSG E     C      RHD    EDV  AC  GG
Sbjct: 502 NKVVMSGVKCSGTELSLAHC------RHD---GEDV--ACPQGG 534



 Score =  127 bits (319), Expect = 5e-29
 Identities = 79/221 (35%), Positives = 116/221 (52%), Gaps = 12/221 (5%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           VRLRGG    EG VEV  +G WGTVC   WD   ASV+C +L  G    A      G G+
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385

Query: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
            PI+ + ++C G+E++I+ C+ +    G C  +  A V C+         +RL GG + +
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFNAESQG-CNHEEDAGVRCNTPAMGLQKKLRLNGGRNPY 444

Query: 290 EGRVELYHAGQ----WGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG---SGPV 342
           EGRVE+         WG VC   W   +A V+CRQLGL   + A+ + ++  G   S  V
Sbjct: 445 EGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKV 504

Query: 343 MLDEVRCTGNELSIEQCPKSSWGEHNC---GHKEDAGVSCT 380
           ++  V+C+G ELS+  C +    +  C   G +  AGV+C+
Sbjct: 505 VMSGVKCSGTELSLAHC-RHDGEDVACPQGGVQYGAGVACS 544



 Score =  103 bits (258), Expect = 5e-22
 Identities = 57/173 (32%), Positives = 93/173 (53%), Gaps = 17/173 (9%)

Query: 505 GENKK--EGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPI 562
           G+ +K  EGRVEV+ +GQWGT+CDD ++   A V+CR+LGY         + +G+G+GPI
Sbjct: 62  GQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPI 121

Query: 563 HVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSS----- 617
            +DN+ CTGNE +LA C     G  +C+H+ED GV+C    K+  G     SL +     
Sbjct: 122 WLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCS--DKRIPGFKFDNSLINQIENL 179

Query: 618 --------VCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCG 662
                   +  +   +R++  ++ G   ++ G  W+       +  + R++CG
Sbjct: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCG 232


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  211 bits (537), Expect = 2e-54
 Identities = 103/230 (44%), Positives = 127/230 (55%), Gaps = 24/230 (10%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGS 339
           +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A   A FG+GS
Sbjct: 18  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77

Query: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------------------- 380
           GP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C+                   
Sbjct: 78  GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137

Query: 381 ----PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQA 436
               P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQLG  +   A
Sbjct: 138 SPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 197

Query: 437 SAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC 485
             N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C
Sbjct: 198 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247



 Score =  192 bits (487), Expect = 1e-48
 Identities = 101/232 (43%), Positives = 125/232 (53%), Gaps = 21/232 (9%)

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEEST 445
           +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQLG  +   A  N  F + +
Sbjct: 18  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77

Query: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGE--------------- 490
           GPI LDDV CSG E+    C    W  H+C H ED  + C  G                 
Sbjct: 78  GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137

Query: 491 ---GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPA 547
              G   SL   +RL++G ++ +GRVEV   G WGT+CDD W   DA V+CRQLG     
Sbjct: 138 SPIGPESSLA--LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 195

Query: 548 RARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
            A   A FG+G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 196 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247



 Score =  183 bits (464), Expect = 7e-46
 Identities = 96/232 (41%), Positives = 122/232 (52%), Gaps = 20/232 (8%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G   +A      G G
Sbjct: 17  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 76

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCS----------------FS 272
             PI   +VRC G+E  +  C  + W    C     A V CS                F 
Sbjct: 77  SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFL 136

Query: 273 HGPTFP----IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAK 328
             P  P     +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      
Sbjct: 137 CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 196

Query: 329 AWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT 380
           A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+
Sbjct: 197 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 40/104 (38%), Positives = 50/104 (48%)

Query: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228
           ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 147 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 206

Query: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFS 272
             PI   +VRC G E  +  C  + W    C     A V CS S
Sbjct: 207 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  211 bits (536), Expect = 3e-54
 Identities = 136/405 (33%), Positives = 190/405 (46%), Gaps = 50/405 (12%)

Query: 281 RLAG-GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGS 339
           RLAG     +EGRVE+  AG+WGT+CDD +    A ++CR+LG +      H A +G G+
Sbjct: 45  RLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGT 104

Query: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------------------T 380
           G + LD + C+G E S+ +C    WG  +C H EDAGV C                    
Sbjct: 105 GRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHL 164

Query: 381 PLTDGVIRLAGGKGSH-----EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQ 435
            + +  IR A G G       EG +EV     W  VCD GW+  N++VVC  LGF   K+
Sbjct: 165 QVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKR 224

Query: 436 ASANHF----EESTGPIWLDDVSCSGKETRFLQCSRRQWGRHD---CSHREDVSIACYPG 488
            +A  +    +       L  V+C G E     CS   +  +D   C       ++C PG
Sbjct: 225 VNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPG 284

Query: 489 -----GEGHRLSLGFP------VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVI 537
                  G +            VRL  G +  EGRVEV     WGT+CD  W    A+V+
Sbjct: 285 PVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVV 344

Query: 538 CRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGV 597
           CR+LG+     A + A  G+G G IH+  V+C+G E SL  C  ++I   +C HS+DAGV
Sbjct: 345 CRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGV 404

Query: 598 ICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRI-IGGKNSLRGG 641
            C+         +  E+   + G R  H  +  + IGG   LR G
Sbjct: 405 RCNL------PYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWG 443



 Score =  183 bits (465), Expect = 5e-46
 Identities = 146/487 (29%), Positives = 197/487 (40%), Gaps = 76/487 (15%)

Query: 176 KNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQL----QLGGKGIAKQTPFSGLGLIP 231
           +  +EG VE+  +G WGT+C   +    A ++C +L      G    AK  P +G     
Sbjct: 51  RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTG----R 106

Query: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP------------- 278
           I+  N+ C G E+++  C    W    C     A V C     P F              
Sbjct: 107 IWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV 166

Query: 279 ---IIRLAGG-----SSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG---IA 327
               IR A G       V EG VE+     W  VCD  W   ++ V+C  LG      + 
Sbjct: 167 EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVN 226

Query: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHN---CGHKEDAGVSCT---- 380
            A+++           L  V C G E  +  C    +  ++   C     A VSC     
Sbjct: 227 AAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPV 286

Query: 381 --------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR 426
                         P  +  +RL GG    EGR+EV     WGTVCD  W      VVCR
Sbjct: 287 YAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCR 346

Query: 427 QLGFKYGKQA-SANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC 485
           +LGF   ++A S     +  G I L +V CSG+E    +C  +     DCSH +D  + C
Sbjct: 347 ELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406

Query: 486 ---YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFING----QWGTICDDGWTDKDAAVIC 538
              Y G E         +RL  G ++ EGRVEV I G    +WG IC D W   +A V C
Sbjct: 407 NLPYTGAETR-------IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459

Query: 539 RQ--LGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRH-NCRHSE-- 593
           RQ  LGY       T  +       + +  V+CTG E SL  C     G H  C+ +   
Sbjct: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH--GTHITCKRTGTR 517

Query: 594 -DAGVIC 599
             AGVIC
Sbjct: 518 FTAGVIC 524



 Score =  138 bits (347), Expect = 3e-32
 Identities = 86/224 (38%), Positives = 113/224 (50%), Gaps = 18/224 (8%)

Query: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
           VRL+GG +  EG VEV  +  WGTVC   WD   ASV+C +L  G    A      G G+
Sbjct: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366

Query: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
             I+ S VRC G E ++  C         C     A V C+  +      IRL+GG S H
Sbjct: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQH 426

Query: 290 EGRVELYHAG----QWGTVCDDQWDDADAEVICRQLGLS----GIAKAWHQAYFGEGS-G 340
           EGRVE+   G    +WG +C D W   +A V CRQLGL     G+ + W   Y+  G+  
Sbjct: 427 EGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW---YWDSGNIT 483

Query: 341 PVMLDEVRCTGNELSIEQCPKSSWGEH----NCGHKEDAGVSCT 380
            V++  VRCTG ELS++QC  +  G H      G +  AGV C+
Sbjct: 484 EVVMSGVRCTGTELSLDQC--AHHGTHITCKRTGTRFTAGVICS 525


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  187 bits (476), Expect = 3e-47
 Identities = 122/363 (33%), Positives = 177/363 (48%), Gaps = 62/363 (17%)

Query: 520 QWGTICDDGWTDKDAAVICRQLGYKGPARARTMAY--FGEGKGPIHVDNVKCTGNERSLA 577
           QW  IC   W D  +   C+QLG++   R   +A+  F      +  ++           
Sbjct: 245 QWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNST---------- 294

Query: 578 DCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNS 637
             I++ + R  C       + C +                 CGLR +     RI+GG  +
Sbjct: 295 --IQESLHRSECPSQRYISLQCSH-----------------CGLRAM---TGRIVGGALA 332

Query: 638 LRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCF----KRYGNSTRSYAVRVG 693
               WPWQVSL   ++H     +CG TL+ + WVLTAAHCF    ++     + YA    
Sbjct: 333 SDSKWPWQVSLHFGTTH-----ICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYA-GTS 386

Query: 694 DYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPL 753
           + H L      E   + +I+I+  Y  +  DYDIAL+RL  P       S+H+ PACLP+
Sbjct: 387 NLHQL-----PEAASIAEIIINSNYTDEEDDYDIALMRLSKP----LTLSAHIHPACLPM 437

Query: 754 WRERPQKTASNCYITGWGDTGRAYSRT---LQQAAIPLLPKRFCEER--YKGRFTGRMLC 808
              +       C+ITG+G T     +T   L++  + L+  + C +   Y    T RM+C
Sbjct: 438 -HGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMC 496

Query: 809 AGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPW 868
           AG+L   +  DSCQGDSGGPL+CE+    W + GVTSWG GCG ++ PGVYTKV+  +PW
Sbjct: 497 AGDLRGGR--DSCQGDSGGPLVCEQ-NNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPW 553

Query: 869 IKS 871
           I S
Sbjct: 554 IYS 556



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 17/72 (23%), Positives = 28/72 (38%)

Query: 300 QWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC 359
           QW  +C   W+D+ +E  C+QLG     +    A+    +   +L         L   +C
Sbjct: 245 QWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSEC 304

Query: 360 PKSSWGEHNCGH 371
           P   +    C H
Sbjct: 305 PSQRYISLQCSH 316



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 3/54 (5%)

Query: 161 GYCDCRHGSVRLRGGKNEFEGTV-EVYA--SGVWGTVCSSHWDDSDASVICHQL 211
           G  DC+  S  L   + +++ ++ ++Y+  S  W  +CSS+W+DS +   C QL
Sbjct: 213 GVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQL 266


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score =  179 bits (453), Expect = 1e-44
 Identities = 132/434 (30%), Positives = 200/434 (46%), Gaps = 56/434 (12%)

Query: 447  PIWLDDVSCSGKETRFLQC------SRRQW--GRHDCSHREDVSIACYPGGEGHRLSLGF 498
            P ++D+ +CS  +   L+C      SR  W  G  DCS   D         E   ++L  
Sbjct: 644  PDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSD---------EWDCVTLSI 694

Query: 499  PVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEG 558
             V             E  +       C DGW +  + + C+Q+G   P+  + +    + 
Sbjct: 695  NVNSSSFLMVHRAATEHHV-------CADGWQEILSQLACKQMGLGEPSVTKLIQEQEKE 747

Query: 559  KGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSV 618
               + + +   + N  +L + +   +   +C       ++C                   
Sbjct: 748  PRWLTLHSNWESLNGTTLHELL---VNGQSCESRSKISLLCT---------------KQD 789

Query: 619  CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCF 678
            CG R   R  KRI+GG+ S  G WPWQ SL+ + S      +CG  L++  WVLT AHCF
Sbjct: 790  CGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGH----ICGCVLIAKKWVLTVAHCF 845

Query: 679  KRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQ 738
            +   N+   + V +G  +   P  F +   V+ I++H  Y     DYDI++V L     +
Sbjct: 846  EGRENAA-VWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISE 904

Query: 739  CARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERY 798
                + +V P CLP   E+  +  + CYITGWG  G      LQ+  + ++    C+  +
Sbjct: 905  ----TGYVRPVCLPN-PEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYF 959

Query: 799  KGR-FTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKD-SP 856
              +  T RM+CAG  +E   VDSC GDSGGPL+CE+PG  W ++G+TSWG  C  K   P
Sbjct: 960  DMKTITTRMICAG--YESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGP 1017

Query: 857  GVYTKVSAFVPWIK 870
            GVY+ VS FV WIK
Sbjct: 1018 GVYSNVSYFVEWIK 1031



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 4/103 (3%)

Query: 411 VCDDGWTELNTYVVCRQLGFKYGKQASANHF-EESTGPIWLDDVSCSGKETRFLQCSRRQ 469
           VC DGW E+ + + C+Q+G   G+ +      E+   P WL  +  + +           
Sbjct: 713 VCADGWQEILSQLACKQMGL--GEPSVTKLIQEQEKEPRWL-TLHSNWESLNGTTLHELL 769

Query: 470 WGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGR 512
                C  R  +S+ C     G R +     R++ G   + GR
Sbjct: 770 VNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGR 812


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  178 bits (452), Expect = 2e-44
 Identities = 103/249 (41%), Positives = 144/249 (57%), Gaps = 16/249 (6%)

Query: 630 RIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYG-NSTRSY 688
           RI+GG  S+RG WPWQV+L   S     R LCG +++ + W+LTAAHCF  YG  S +  
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSP--TQRHLCGGSIIGNQWILTAAHCF--YGVESPKIL 442

Query: 689 AVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLP 748
            V  G  +    +E     GVQ+I+IH +Y+   S YDIAL++L    E    ++    P
Sbjct: 443 RVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKL----ETTVNYTDSQRP 498

Query: 749 ACLPLWRERPQKTASNCYITGWG--DTGRAYSRTLQQAAIPLLPKRFCEERYKG-RFTGR 805
            CLP   +R     ++C++TGWG          TLQ+A IPL+    C++RY+G + T +
Sbjct: 499 ICLPSKGDR-NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHK 557

Query: 806 MLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 865
           M+CAG     K  D+C+GDSGGPL C+   E W + G+TSWG GC  ++ PGVYT V  +
Sbjct: 558 MICAGYREGGK--DACKGDSGGPLSCKH-NEVWHLVGITSWGEGCAQRERPGVYTNVVEY 614

Query: 866 VPWIKSVTK 874
           V WI   T+
Sbjct: 615 VDWILEKTQ 623


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  176 bits (447), Expect = 6e-44
 Identities = 105/242 (43%), Positives = 133/242 (54%), Gaps = 16/242 (6%)

Query: 630  RIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYA 689
            RI+GG  + RG WPWQVSL L+         CGA L++  W+L+AAHCF  YG+  +  A
Sbjct: 826  RIVGGSAAGRGEWPWQVSLWLRRREHR----CGAVLVAERWLLSAAHCFDVYGDPKQWAA 881

Query: 690  VRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPA 749
                 + +    + E    V +I  H  Y     DYD+AL+ L GP     R S  V P 
Sbjct: 882  FLGTPFLSGAEGQLER---VARIYKHPFYNLYTLDYDVALLELAGP----VRRSRLVRPI 934

Query: 750  CLPLWRERPQKTASNCYITGWGDT--GRAYSRTLQQAAIPLLPKRFCEERYKGRFTGRML 807
            CLP    RP    + C ITGWG    G + +R LQ+AA+ LL ++ C   Y  + + RML
Sbjct: 935  CLPEPAPRPPD-GTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRML 993

Query: 808  CAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVP 867
            CAG       VDSC GD+GGPL C  P   WV+ GVTSWGYGCG    PGVYT+V+A   
Sbjct: 994  CAG--FPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRG 1051

Query: 868  WI 869
            WI
Sbjct: 1052 WI 1053



 Score =  168 bits (426), Expect = 2e-41
 Identities = 109/326 (33%), Positives = 149/326 (45%), Gaps = 36/326 (11%)

Query: 556 GEGKGPIHVDNVK---CTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNK 612
           G  KGP+   + K   C GN  S  +          C   ED              +   
Sbjct: 138 GRHKGPLAERDFKSGRCPGNSFSCGNSQCVTKVNPECDDQEDC-------------SDGS 184

Query: 613 ESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVL 672
           +     CGL+   R   RI+GG  +  G +PWQ SLR    H      CGA ++++ W++
Sbjct: 185 DEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEH-----FCGAAIINARWLV 239

Query: 673 TAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRL 732
           +AAHCF  + + T+ +   VG  +    E       V QIV H  Y  D +D+D+A++ L
Sbjct: 240 SAAHCFNEFQDPTK-WVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLEL 298

Query: 733 QGPEEQCARFSSHVLPACLPLWRE--RPQKTASNCYITGWGDTGRAY---SRTLQQAAIP 787
             P      F  H+ P CLP       P K    C I+GWG     +      LQ+A + 
Sbjct: 299 TSP----LPFGRHIQPVCLPAATHIFPPSK---KCLISGWGYLKEDFLVKPEVLQKATVE 351

Query: 788 LLPKRFCEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
           LL +  C   Y    T RM+CAG L    +VDSCQGDSGGPL+CE P   + + G+ SWG
Sbjct: 352 LLDQALCASLYGHSLTDRMVCAGYLDG--KVDSCQGDSGGPLVCEEPSGRFFLAGIVSWG 409

Query: 848 YGCGVKDSPGVYTKVSAFVPWIKSVT 873
            GC     PGVY +V+    WI   T
Sbjct: 410 IGCAEARRPGVYARVTRLRDWILEAT 435



 Score =  164 bits (414), Expect = 4e-40
 Identities = 94/259 (36%), Positives = 139/259 (53%), Gaps = 21/259 (8%)

Query: 619 CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCF 678
           CG R    +  R++GG  +  G  PWQVSL+  S H      CGAT++   W+L+AAHCF
Sbjct: 492 CGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRH-----FCGATVVGDRWLLSAAHCF 546

Query: 679 KRYGNSTRSYAVR--VGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPE 736
               N T+   VR  +G    L       +IG++++V+H  Y P   D+D+A++ L  P 
Sbjct: 547 ----NHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASP- 601

Query: 737 EQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYS---RTLQQAAIPLLPKRF 793
                F+ ++ P CLPL  ++       C I+GWG+T    +     LQ+A++ ++ ++ 
Sbjct: 602 ---LAFNKYIQPVCLPLAIQK-FPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKT 657

Query: 794 CEERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVK 853
           C   Y    T RM+CAG L    +VDSCQGDSGGPL CE     + + G+ SWG GC   
Sbjct: 658 CSVLYNFSLTDRMICAGFLEG--KVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQV 715

Query: 854 DSPGVYTKVSAFVPWIKSV 872
             PGVYT+++    WI  +
Sbjct: 716 KKPGVYTRITRLKGWILEI 734


>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
           [Homo sapiens]
          Length = 562

 Score =  172 bits (437), Expect = 9e-43
 Identities = 112/305 (36%), Positives = 161/305 (52%), Gaps = 26/305 (8%)

Query: 584 IGRHN-CRHSE-DAGVICDYF-GKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRG 640
           +G+HN CR+ + DA   C     ++ +         S CGLR   + Q RI GG  +   
Sbjct: 261 LGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIA 320

Query: 641 GWPWQVSLRLKSSHGDG-RLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLV 699
             PWQ ++  K     G R LCG  L+SSCW+L+AAHCF+          V +G  + +V
Sbjct: 321 SHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERF-PPHHLTVILGRTYRVV 379

Query: 700 PEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQ 759
           P E E++  V++ ++H+E+  D  D DIAL++L+    +CA+ SS V   CLP   +   
Sbjct: 380 PGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPP-ADLQL 438

Query: 760 KTASNCYITGWGD---TGRAYSRTLQQAAIPLLPKRFCEERY--KGRFTGRMLCAG---- 810
              + C ++G+G        YS  L++A + L P   C  ++      T  MLCAG    
Sbjct: 439 PDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRS 498

Query: 811 -----NLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 865
                NLH     D+CQGDSGGPL+C   G   +V G+ SWG GCG KD PGVYTKV+ +
Sbjct: 499 GGPQANLH-----DACQGDSGGPLVCLNDGRMTLV-GIISWGLGCGQKDVPGVYTKVTNY 552

Query: 866 VPWIK 870
           + WI+
Sbjct: 553 LDWIR 557



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 7/68 (10%)

Query: 101 SVTDFGAPCLRWAEV----PPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARG 156
           S+T+ GA CL W  +      +  ++P A    L   +HN+CR+PDG  +PWC     R 
Sbjct: 228 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLG--KHNYCRNPDGDAKPWCHVLKNR- 284

Query: 157 KVDWGYCD 164
           ++ W YCD
Sbjct: 285 RLTWEYCD 292



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 11/97 (11%)

Query: 101 SVTDFGAPCLRWAEVP----PFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARG 156
           S  + GA C  W        P+  R P A   +L    HN+CR+PD   +PWC+   A G
Sbjct: 140 STAESGAECTNWNSSALAQKPYSGRRPDA--IRLGLGNHNYCRNPDRDSKPWCYVFKA-G 196

Query: 157 KVDWGYCD---CRHG-SVRLRGGKNEFEGTVEVYASG 189
           K    +C    C  G S    G  + + GT  +  SG
Sbjct: 197 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESG 233


>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
           [Homo sapiens]
          Length = 516

 Score =  172 bits (437), Expect = 9e-43
 Identities = 112/305 (36%), Positives = 161/305 (52%), Gaps = 26/305 (8%)

Query: 584 IGRHN-CRHSE-DAGVICDYF-GKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRG 640
           +G+HN CR+ + DA   C     ++ +         S CGLR   + Q RI GG  +   
Sbjct: 215 LGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIA 274

Query: 641 GWPWQVSLRLKSSHGDG-RLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLV 699
             PWQ ++  K     G R LCG  L+SSCW+L+AAHCF+          V +G  + +V
Sbjct: 275 SHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERF-PPHHLTVILGRTYRVV 333

Query: 700 PEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQ 759
           P E E++  V++ ++H+E+  D  D DIAL++L+    +CA+ SS V   CLP   +   
Sbjct: 334 PGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPP-ADLQL 392

Query: 760 KTASNCYITGWGD---TGRAYSRTLQQAAIPLLPKRFCEERY--KGRFTGRMLCAG---- 810
              + C ++G+G        YS  L++A + L P   C  ++      T  MLCAG    
Sbjct: 393 PDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRS 452

Query: 811 -----NLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAF 865
                NLH     D+CQGDSGGPL+C   G   +V G+ SWG GCG KD PGVYTKV+ +
Sbjct: 453 GGPQANLH-----DACQGDSGGPLVCLNDGRMTLV-GIISWGLGCGQKDVPGVYTKVTNY 506

Query: 866 VPWIK 870
           + WI+
Sbjct: 507 LDWIR 511



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 7/68 (10%)

Query: 101 SVTDFGAPCLRWAEV----PPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARG 156
           S+T+ GA CL W  +      +  ++P A    L   +HN+CR+PDG  +PWC     R 
Sbjct: 182 SLTESGASCLPWNSMILIGKVYTAQNPSAQALGLG--KHNYCRNPDGDAKPWCHVLKNR- 238

Query: 157 KVDWGYCD 164
           ++ W YCD
Sbjct: 239 RLTWEYCD 246



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 11/97 (11%)

Query: 101 SVTDFGAPCLRWAEVP----PFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARG 156
           S  + GA C  W        P+  R P A   +L    HN+CR+PD   +PWC+   A G
Sbjct: 94  STAESGAECTNWNSSALAQKPYSGRRPDA--IRLGLGNHNYCRNPDRDSKPWCYVFKA-G 150

Query: 157 KVDWGYCD---CRHG-SVRLRGGKNEFEGTVEVYASG 189
           K    +C    C  G S    G  + + GT  +  SG
Sbjct: 151 KYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESG 187


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  172 bits (436), Expect = 1e-42
 Identities = 125/370 (33%), Positives = 180/370 (48%), Gaps = 70/370 (18%)

Query: 519 GQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIH-VDNVKCTGNERSLA 577
           G W + C D +T+  A   CRQ+GY      R +       GP   +D V+ T N + L 
Sbjct: 121 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEI-----GPDQDLDVVEITENSQELR 175

Query: 578 DCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSV----CGLRLLHRRQKRIIG 633
                                     + +SG     SL S+    CG  L   +  R++G
Sbjct: 176 M-------------------------RNSSGPCLSGSLVSLHCLACGKSL---KTPRVVG 207

Query: 634 GKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGN----STRSYA 689
           G+ +    WPWQVS++    H     +CG ++L   WVLTAAHCF+++ +      R+ +
Sbjct: 208 GEEASVDSWPWQVSIQYDKQH-----VCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGS 262

Query: 690 VRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPA 749
            ++G + +L          V +I+I         D DIAL++LQ P      FS  V P 
Sbjct: 263 DKLGSFPSLA---------VAKIIIIEFNPMYPKDNDIALMKLQFP----LTFSGTVRPI 309

Query: 750 CLPLWRERPQKTASNCYITGWGDT---GRAYSRTLQQAAIPLLPKRFC--EERYKGRFTG 804
           CLP + E     A+  +I GWG T   G   S  L QA++ ++    C  ++ Y+G  T 
Sbjct: 310 CLPFFDEE-LTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTE 368

Query: 805 RMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSA 864
           +M+CAG       VD+CQGDSGGPLM +   + W V G+ SWGYGCG   +PGVYTKVSA
Sbjct: 369 KMMCAGI--PEGGVDTCQGDSGGPLMYQ--SDQWHVVGIVSWGYGCGGPSTPGVYTKVSA 424

Query: 865 FVPWIKSVTK 874
           ++ WI +V K
Sbjct: 425 YLNWIYNVWK 434



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 12/26 (46%), Positives = 16/26 (61%)

Query: 299 GQWGTVCDDQWDDADAEVICRQLGLS 324
           G W + C D + +A AE  CRQ+G S
Sbjct: 121 GNWFSACFDNFTEALAETACRQMGYS 146


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  172 bits (436), Expect = 1e-42
 Identities = 125/370 (33%), Positives = 179/370 (48%), Gaps = 55/370 (14%)

Query: 513 VEVFINGQWGTICDDGWTDKDAAVICRQLG---YKGPARARTMAYFGEGKGP-IHVDNVK 568
           ++VF    W T+C D W    A V C QLG   Y      R  +  G+ +   + +D++ 
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLL 176

Query: 569 CTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRR- 627
                 +L   +     R  C       + C                 + CG    HRR 
Sbjct: 177 PDDKVTALHHSVYV---REGCASGHVVTLQC-----------------TACG----HRRG 212

Query: 628 -QKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHC-FKRYGNST 685
              RI+GG  SL   WPWQ SL+ +  H     LCG ++++  W++TAAHC +  Y    
Sbjct: 213 YSSRIVGGNMSLLSQWPWQASLQFQGYH-----LCGGSVITPLWIITAAHCVYDLY--LP 265

Query: 686 RSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSH 745
           +S+ ++VG   +L+       + V++IV H +Y+P R   DIAL++L GP      F+  
Sbjct: 266 KSWTIQVG-LVSLLDNPAPSHL-VEKIVYHSKYKPKRLGNDIALMKLAGP----LTFNEM 319

Query: 746 VLPACLPLWRERPQKTASNCYITGWGDT----GRAYSRTLQQAAIPLLPKRFCEER--YK 799
           + P CLP   E        C+ +GWG T    G A S  L  AA+PL+  + C  R  Y 
Sbjct: 320 IQPVCLPNSEEN-FPDGKVCWTSGWGATEDGAGDA-SPVLNHAAVPLISNKICNHRDVYG 377

Query: 800 GRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVY 859
           G  +  MLCAG L     VDSCQGDSGGPL+C+     W + G TS+G GC   + PGVY
Sbjct: 378 GIISPSMLCAGYLTGG--VDSCQGDSGGPLVCQER-RLWKLVGATSFGIGCAEVNKPGVY 434

Query: 860 TKVSAFVPWI 869
           T+V++F+ WI
Sbjct: 435 TRVTSFLDWI 444



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)

Query: 161 GYCDCRHGSVRLR----GGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQL 211
           G  DC+ G    R    GG+N     ++V+ +  W T+CS  W    A+V C QL
Sbjct: 94  GVSDCKDGEDEYRCVRVGGQN---AVLQVFTAASWKTMCSDDWKGHYANVACAQL 145



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLG 322
           +R+ G ++V    ++++ A  W T+C D W    A V C QLG
Sbjct: 108 VRVGGQNAV----LQVFTAASWKTMCSDDWKGHYANVACAQLG 146



 Score = 33.9 bits (76), Expect = 0.68
 Identities = 14/37 (37%), Positives = 17/37 (45%)

Query: 394 GSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF 430
           G     L+V+    W T+C D W      V C QLGF
Sbjct: 111 GGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGF 147


>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
           sapiens]
          Length = 414

 Score =  171 bits (433), Expect = 3e-42
 Identities = 104/279 (37%), Positives = 150/279 (53%), Gaps = 15/279 (5%)

Query: 603 GKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCG 662
           GKK S  S  E L   CG + L  R K IIGG+ +     PW  ++  +   G    +CG
Sbjct: 137 GKKPS--SPPEELKFQCGQKTLRPRFK-IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCG 193

Query: 663 ATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDR 722
            +L+S CWV++A HCF  Y      Y V +G        + E +  V+ +++H++Y  D 
Sbjct: 194 GSLISPCWVISATHCFIDYPKK-EDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADT 252

Query: 723 SDY--DIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWG---DTGRAY 777
             +  DIAL++++  E +CA+ S  +   CLP     PQ   ++C ITG+G    T   Y
Sbjct: 253 LAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQ-FGTSCEITGFGKENSTDYLY 311

Query: 778 SRTLQQAAIPLLPKRFCEER--YKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPG 835
              L+   + L+  R C++   Y    T +MLCA +     + DSCQGDSGGPL+C   G
Sbjct: 312 PEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAAD--PQWKTDSCQGDSGGPLVCSLQG 369

Query: 836 ESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTK 874
              +  G+ SWG GC +KD PGVYT+VS F+PWI+S TK
Sbjct: 370 RMTLT-GIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 407



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 101 SVTDFGAPCLRW--AEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCF 150
           S    G PCL W  A V      +  +   QL   +HN+CR+PD   RPWC+
Sbjct: 66  STDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCY 117


>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
           [Homo sapiens]
          Length = 431

 Score =  171 bits (433), Expect = 3e-42
 Identities = 104/279 (37%), Positives = 150/279 (53%), Gaps = 15/279 (5%)

Query: 603 GKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCG 662
           GKK S  S  E L   CG + L  R K IIGG+ +     PW  ++  +   G    +CG
Sbjct: 154 GKKPS--SPPEELKFQCGQKTLRPRFK-IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCG 210

Query: 663 ATLLSSCWVLTAAHCFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDR 722
            +L+S CWV++A HCF  Y      Y V +G        + E +  V+ +++H++Y  D 
Sbjct: 211 GSLISPCWVISATHCFIDYPKK-EDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADT 269

Query: 723 SDY--DIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWG---DTGRAY 777
             +  DIAL++++  E +CA+ S  +   CLP     PQ   ++C ITG+G    T   Y
Sbjct: 270 LAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQ-FGTSCEITGFGKENSTDYLY 328

Query: 778 SRTLQQAAIPLLPKRFCEER--YKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPG 835
              L+   + L+  R C++   Y    T +MLCA +     + DSCQGDSGGPL+C   G
Sbjct: 329 PEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAAD--PQWKTDSCQGDSGGPLVCSLQG 386

Query: 836 ESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTK 874
              +  G+ SWG GC +KD PGVYT+VS F+PWI+S TK
Sbjct: 387 RMTLT-GIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 424



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 101 SVTDFGAPCLRW--AEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCF 150
           S    G PCL W  A V      +  +   QL   +HN+CR+PD   RPWC+
Sbjct: 83  STDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCY 134


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  171 bits (433), Expect = 3e-42
 Identities = 98/257 (38%), Positives = 142/257 (55%), Gaps = 18/257 (7%)

Query: 619 CGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCF 678
           CGL+       RI+GG  S  G WPWQ SL+++     GR +CG  L++  WV+TAAHCF
Sbjct: 568 CGLQ---GPSSRIVGGAVSSEGEWPWQASLQVR-----GRHICGGALIADRWVITAAHCF 619

Query: 679 KRYGN-STRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQGPEE 737
           +     ST  + V +G          E    V ++++H  +  D  DYD+AL++L  P  
Sbjct: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679

Query: 738 QCARFSSHVLPACLPLWRERPQKTASNCYITGWGDT--GRAYSRTLQQAAIPLLPKRFCE 795
           +    S+ V P CLP  R    +   +C+ITGWG    G   S  LQ+  + L+P+  C 
Sbjct: 680 R----SAAVRPVCLPA-RSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCS 734

Query: 796 ERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDS 855
           E Y+ + T RMLCAG  +   + D+CQGDSGGPL+C+     W + G+ SWG GCG  + 
Sbjct: 735 EVYRYQVTPRMLCAG--YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNY 792

Query: 856 PGVYTKVSAFVPWIKSV 872
            GVYT+++  + WI+ V
Sbjct: 793 FGVYTRITGVISWIQQV 809


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  171 bits (432), Expect = 4e-42
 Identities = 100/246 (40%), Positives = 137/246 (55%), Gaps = 21/246 (8%)

Query: 630 RIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYA 689
           RIIGG ++L GGWPWQVSL     H  G   CGA+++S  W+L+AAHCF  +GN      
Sbjct: 479 RIIGGTDTLEGGWPWQVSL-----HFVGSAYCGASVISREWLLSAAHCF--HGNRLSDPT 531

Query: 690 VRVGDYHTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQ--GPEEQCARFSSHVL 747
                    V    +    V++IV+H  Y     DYDIAL++L    PE         + 
Sbjct: 532 PWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPET----LKQLIQ 587

Query: 748 PACLPLWRERPQKTASNCYITGWGDTGRAYSR---TLQQAAIPLLPKRFCEERYKGRFTG 804
           P C+P   +R  ++   C++TGWG    A ++    LQQA + L+ +  C   Y G  T 
Sbjct: 588 PICIPPTGQRV-RSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTY-GIITS 645

Query: 805 RMLCAGNLHEHKRVDSCQGDSGGPLMCERPGES-WVVYGVTSWGYGCGVKDSPGVYTKVS 863
           RMLCAG +   +  D+C+GDSGGPL C R  +  W++ G+ SWG+G G  + PGVYT+VS
Sbjct: 646 RMLCAGIMSGKR--DACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVS 703

Query: 864 AFVPWI 869
            FVPWI
Sbjct: 704 NFVPWI 709


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  170 bits (431), Expect = 5e-42
 Identities = 120/382 (31%), Positives = 175/382 (45%), Gaps = 53/382 (13%)

Query: 500  VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGK 559
            VR  +G     G V   I   W T C + WT + +  +C+ LG      ++ +  F    
Sbjct: 678  VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPI--FSTDG 735

Query: 560  GPIHVDNVKCTGNE--RSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSS 617
            GP    N    G+        C++  + R  C H                          
Sbjct: 736  GPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKS------------------------ 771

Query: 618  VCGLRLLHRR-QKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676
             CG +L  +    +I+GG N+  G WPW V L     +  GRLLCGA+L+SS W+++AAH
Sbjct: 772  -CGKKLAAQDITPKIVGGSNAKEGAWPWVVGL-----YYGGRLLCGASLVSSDWLVSAAH 825

Query: 677  CFKRYGNSTRSYAVRVGDY--HTLVPEEFEEEIGVQQIVIHREYRPDRSDYDIALVRLQG 734
            C          +   +G +    L   +    + + +IVI+  Y   R D DIA++ L  
Sbjct: 826  CVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRL-IDEIVINPHYNRRRKDNDIAMMHL-- 882

Query: 735  PEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRT----LQQAAIPLLP 790
              E    ++ ++ P CLP    +      NC I GWG     Y  T    LQ+A +PLL 
Sbjct: 883  --EFKVNYTDYIQPICLPE-ENQVFPPGRNCSIAGWGTV--VYQGTTANILQEADVPLLS 937

Query: 791  KRFCEERY-KGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYG 849
               C+++  +   T  M+CAG  +E   +DSCQGDSGGPLMC+     W + GVTS+GY 
Sbjct: 938  NERCQQQMPEYNITENMICAG--YEEGGIDSCQGDSGGPLMCQE-NNRWFLAGVTSFGYK 994

Query: 850  CGVKDSPGVYTKVSAFVPWIKS 871
            C + + PGVY +VS F  WI+S
Sbjct: 995  CALPNRPGVYARVSRFTEWIQS 1016



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 40/159 (25%), Positives = 57/159 (35%), Gaps = 34/159 (21%)

Query: 161 GYCDCRHGS-----VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGG 215
           G+  C  GS     VR   G     G V      +W T C+ +W    ++ +C  L LG 
Sbjct: 664 GHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGS 723

Query: 216 KGIAKQT------PFSGLGLIP----IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265
              +K        PF  L   P    I   + +C  D    L C         C +K+AA
Sbjct: 724 GNSSKPIFSTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHK-----SCGKKLAA 778

Query: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGR----VELYHAGQ 300
                          ++ GGS+  EG     V LY+ G+
Sbjct: 779 QDITP----------KIVGGSNAKEGAWPWVVGLYYGGR 807



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 18/138 (13%)

Query: 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGL-SGIAKAWHQAYFGEG 338
           +R   G++ + G V       W T C + W    +  +C+ LGL SG +    +  F   
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSS---KPIFSTD 734

Query: 339 SGPVMLDEVRCTGNEL--SIEQCPKSSWGEHNCGHKEDAGVSC---TPLTDGVIRLAGGK 393
            GP +       G+ +    +QC + S     C HK     SC       D   ++ GG 
Sbjct: 735 GGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHK-----SCGKKLAAQDITPKIVGGS 789

Query: 394 GSHEGR----LEVYYRGQ 407
            + EG     + +YY G+
Sbjct: 790 NAKEGAWPWVVGLYYGGR 807



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 14/128 (10%)

Query: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEESTG 446
           +R   G  ++ G +    +  W T C + WT   +  VC+ LG   G  +S   F    G
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSG-NSSKPIFSTDGG 736

Query: 447 PIWLDDVSCSGK--ETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSL-GFPVRLM 503
           P    + +  G    T   QC +    R  C+H+     +C     G +L+      +++
Sbjct: 737 PFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHK-----SC-----GKKLAAQDITPKIV 786

Query: 504 DGENKKEG 511
            G N KEG
Sbjct: 787 GGSNAKEG 794


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  170 bits (431), Expect = 5e-42
 Identities = 124/408 (30%), Positives = 186/408 (45%), Gaps = 63/408 (15%)

Query: 479 EDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQ--WGTICDDGWTDKDAAV 536
           E+++++C        L    P  +    N ++  +E  +  Q  W  +C +GW+      
Sbjct: 87  EEITLSCSEASAEEALLPALPKTVSFRINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQ 146

Query: 537 ICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIG---------RH 587
           IC  LG+      R   + G     +++ ++K   ++      +   +G         R+
Sbjct: 147 ICWSLGH-----LRLTHHKG-----VNLTDIKLNSSQEFAQ--LSPRLGGFLEEAWQPRN 194

Query: 588 NCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVS 647
           NC   +   + C                 S CG R L     RI+GG++   G WPWQ S
Sbjct: 195 NCTSGQVVSLRC-----------------SECGARPL---ASRIVGGQSVAPGRWPWQAS 234

Query: 648 LRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNST-RSYAVRVGDYHTLVPEEFEEE 706
           + L   H      CG ++L+  WV+TAAHC   +  +   S+ V  G          +  
Sbjct: 235 VALGFRH-----TCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGA 289

Query: 707 IGVQQIVIHREYRPDRSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCY 766
           + V++I+ H  Y     DYD+AL+RLQ        FS  V   CLP  +E+     S C+
Sbjct: 290 L-VERIIPHPLYSAQNHDYDVALLRLQ----TALNFSDTVGAVCLPA-KEQHFPKGSRCW 343

Query: 767 ITGWGDTGRAY---SRTLQQAAIPLLPKRFCEER--YKGRFTGRMLCAGNLHEHKRVDSC 821
           ++GWG T  ++   S  LQ   +PL   + C     Y G  T RMLCAG L    R D+C
Sbjct: 344 VSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDG--RADAC 401

Query: 822 QGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWI 869
           QGDSGGPL+C   G++W + GV SWG GC   + PGVY KV+ F+ WI
Sbjct: 402 QGDSGGPLVCP-DGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWI 448


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,362,219
Number of Sequences: 37866
Number of extensions: 2422893
Number of successful extensions: 15032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 401
Number of HSP's that attempted gapping in prelim test: 9867
Number of HSP's gapped (non-prelim): 3105
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.