Guide to the Human Genome
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Name: TMPRSS6 Sequence: fasta or formatted (811aa) NCBI GI: 23957702
Description:

transmembrane protease, serine 6

Referenced in:

Lipoproteins
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         53           2
 C cysteine            4.7         38           1
 D aspartate           4.9         40           1
 E glutamate           5.4         44           2
 F phenylalanine       3.2         26           2
 G glycine             8.5         69           2
 H histidine           2.2         18           1
 I isoleucine          3.0         24           1
 K lysine              3.5         28           2
 L leucine            11.2         91           3
 M methionine          1.4         11           1
 N asparagine          2.1         17           1
 P proline             5.7         46           1
 Q glutamine           5.1         41           2
 R arginine            6.0         49           2
 S serine              7.8         63           3
 T threonine           3.9         32           1
 V valine              8.6         70           2
 W tryptophan          2.3         19           1
 Y tyrosine            3.9         32           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transmembrane protease, serine 6 
ST14                  0.229   matriptase 
TMPRSS7               0.222   transmembrane protease, serine 7 
TMPRSS9               0.151   transmembrane protease, serine 9 
PRSS33                0.118   protease, serine, 33 
KLKB1                 0.116   plasma kallikrein B1 precursor 
TMPRSS5               0.115   transmembrane protease, serine 5 
TMPRSS11E             0.114   transmembrane protease, serine 11E 
TMPRSS11E2            0.114   transmembrane protease, serine 11E2 
PRSS36                0.114   protease, serine, 36 
TMPRSS13              0.112   transmembrane protease, serine 13 
PRSS22                0.110   protease, serine, 22 
PRSS27                0.110   marapsin 
PRSS8                 0.107   prostasin preproprotein 
PRSS7                 0.106   enterokinase precursor 
PRSS21                0.103   testisin isoform 2 
TPSG1                 0.103   transmembrane tryptase preproprotein 
HPN                   0.103   hepsin 
HPN                   0.103   hepsin 
PRSS21                0.102   testisin isoform 1 
TMPRSS4               0.101   transmembrane protease, serine 4 isoform 1 
TMPRSS2               0.101   transmembrane protease, serine 2 isoform 1 
TMPRSS2               0.101   transmembrane protease, serine 2 isoform 2 
TMPRSS4               0.101   transmembrane protease, serine 4 isoform 3 
F11                   0.100   coagulation factor XI precursor 
TMPRSS11A             0.100   transmembrane protease, serine 11A isoform 2 
TMPRSS11A             0.100   transmembrane protease, serine 11A isoform 1 
TMPRSS11D             0.100   transmembrane protease, serine 11D 
TMPRSS3               0.098   transmembrane protease, serine 3 isoform 1 
CORIN                 0.097   corin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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