Guide to the Human Genome
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Name: PLAU Sequence: fasta or formatted (431aa) NCBI GI: 4505863
Description:

plasminogen activator, urokinase isoform 1 preproprotein

Referenced in:

Coagulation

Other entries for this name:
alt prot [414aa] plasminogen activator, urokinase isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.2         18           2
 C cysteine            5.8         25           1
 D aspartate           4.4         19           1
 E glutamate           4.6         20           2
 F phenylalanine       2.8         12           1
 G glycine             8.4         36           2
 H histidine           3.9         17           2
 I isoleucine          4.4         19           2
 K lysine              6.5         28           2
 L leucine             8.6         37           3
 M methionine          1.9          8           1
 N asparagine          4.4         19           1
 P proline             5.3         23           2
 Q glutamine           4.6         20           2
 R arginine            5.6         24           3
 S serine              7.4         32           2
 T threonine           6.0         26           2
 V valine              5.1         22           2
 W tryptophan          1.9          8           1
 Y tyrosine            4.2         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   plasminogen activator, urokinase isoform 1 preproprot... 
PLAU                  0.941   plasminogen activator, urokinase isoform 2 
PLAT                  0.305   plasminogen activator, tissue isoform 1 preproprotein...
PLAT                  0.305   plasminogen activator, tissue isoform 3 preproprotei...
HGFAC                 0.280   HGF activator preproprotein 
F12                   0.254   coagulation factor XII precursor 
HABP2                 0.245   hyaluronan binding protein 2 preproprotein 
PLG                   0.173   plasminogen 
PRSS12                0.162   neurotrypsin precursor 
LPA                   0.160   lipoprotein Lp(a) precursor 
PRSS33                0.158   protease, serine, 33 
TMPRSS11D             0.152   transmembrane protease, serine 11D 
TMPRSS13              0.149   transmembrane protease, serine 13 
TMPRSS6               0.143   transmembrane protease, serine 6 
KLKB1                 0.142   plasma kallikrein B1 precursor 
PRSS8                 0.141   prostasin preproprotein 
TMPRSS9               0.141   transmembrane protease, serine 9 
KLK13                 0.141   kallikrein 13 precursor 
TMPRSS5               0.138   transmembrane protease, serine 5 
HPN                   0.133   hepsin 
KLK6                  0.133   kallikrein-related peptidase 6 isoform A preproprote...
KLK6                  0.133   kallikrein-related peptidase 6 isoform A preproprotei...
HPN                   0.133   hepsin 
MST1                  0.132   macrophage stimulating 1 (hepatocyte growth factor-...
CTRB1                 0.130   chymotrypsin B1 
CTRL                  0.130   chymotrypsin-like 
PRSS1                 0.130   protease, serine, 1 preproprotein 
PRSS3                 0.130   mesotrypsin isoform 1 preproprotein 
PRSS3                 0.130   mesotrypsin isoform 2 preproprotein 
TPSG1                 0.130   transmembrane tryptase preproprotein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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