Guide to the Human Genome
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Name: HTRA2 Sequence: fasta or formatted (458aa) NCBI GI: 7019477
Description:

HtrA serine peptidase 2 isoform 1 preproprotein

Referenced in:

Serine Proteases

Other entries for this name:
alt prot [361aa] HtrA serine peptidase 2 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.7         49           2
 C cysteine            0.2          1           1
 D aspartate           4.1         19           1
 E glutamate           4.6         21           1
 F phenylalanine       2.0          9           1
 G glycine             9.8         45           3
 H histidine           1.3          6           1
 I isoleucine          5.0         23           1
 K lysine              1.3          6           2
 L leucine             9.8         45           4
 M methionine          1.3          6           2
 N asparagine          2.4         11           1
 P proline             7.4         34           3
 Q glutamine           3.5         16           1
 R arginine            9.6         44           3
 S serine              7.2         33           3
 T threonine           7.0         32           1
 V valine              9.6         44           2
 W tryptophan          1.3          6           1
 Y tyrosine            1.7          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HtrA serine peptidase 2 isoform 1 preproprotein [Homo... 
HTRA2                 0.645   HtrA serine peptidase 2 isoform 2 
HTRA3                 0.362   HtrA serine peptidase 3 
HTRA1                 0.349   HtrA serine peptidase 1 precursor 
HTRA4                 0.308   HtrA serine peptidase 4 precursor 
PDZD11                0.019   PDZ domain containing 11 
TYSND1                0.017   trypsin domain containing 1 isoform a 
LOC100289054          0.014   PREDICTED: hypothetical protein 
LOC100289054          0.014   PREDICTED: hypothetical protein XP_002343716 
SCRIB                 0.011   scribble isoform b 
SCRIB                 0.011   scribble isoform a 
LOC643355             0.011   PREDICTED: hypothetical protein 
CC2D1A                0.011   coiled-coil and C2 domain containing 1A 
ARHGAP23              0.011   Rho GTPase activating protein 23 
PDZK1                 0.010   PDZ domain containing 1 
PDLIM3                0.010   PDZ and LIM domain protein 3 isoform b 
PDLIM3                0.010   PDZ and LIM domain protein 3 isoform a 
BHLHE23               0.010   basic helix-loop-helix domain containing, class B, 4...
ANKRD30B              0.009   ankyrin repeat domain 30B 
DLG5                  0.009   discs large homolog 5 
NRG1                  0.009   neuregulin 1 isoform GGF2 
ANKRD30A              0.008   ankyrin repeat domain 30A 
APEX2                 0.008   apurinic/apyrimidinic endonuclease 2 
RGS12                 0.008   regulator of G-protein signalling 12 isoform 2 
RGS12                 0.008   regulator of G-protein signalling 12 isoform 1 [Homo...
KIAA1244              0.008   brefeldin A-inhibited guanine nucleotide-exchange p...
LOC100293176          0.008   PREDICTED: hypothetical protein 
LOC100294067          0.008   PREDICTED: similar to rCG47812 
MARCH4                0.008   membrane-associated ring finger (C3HC4) 4 
MEX3D                 0.008   ring finger and KH domain containing 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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