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Search of human proteins with 4505303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505303 smooth muscle and non-muscle myosin alkali light
chain 6B [Homo sapiens]
(208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505303 smooth muscle and non-muscle myosin alkali light chai... 419 e-117
gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f... 259 1e-69
gi|17986258 myosin, light chain 6, alkali, smooth muscle and non... 254 4e-68
gi|4557038 atrial/embryonic alkali myosin light chain [Homo sapi... 251 3e-67
gi|50845428 atrial/embryonic alkali myosin light chain [Homo sap... 251 3e-67
gi|88999583 myosin, light chain 6, alkali, smooth muscle and non... 244 3e-65
gi|4557777 slow skeletal ventricular myosin alkali light chain 3... 244 5e-65
gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f... 226 1e-59
gi|58218968 calmodulin 3 [Homo sapiens] 124 7e-29
gi|4502549 calmodulin 2 [Homo sapiens] 124 7e-29
gi|5901912 calmodulin 1 [Homo sapiens] 124 7e-29
gi|4885111 calmodulin-like 3 [Homo sapiens] 123 1e-28
gi|4507617 fast skeletal muscle troponin C [Homo sapiens] 93 1e-19
gi|4507615 troponin C, slow [Homo sapiens] 88 6e-18
gi|4757974 centrin 1 [Homo sapiens] 81 7e-16
gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens] 79 3e-15
gi|46397403 centrin 3 [Homo sapiens] 78 5e-15
gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens] 77 8e-15
gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens] 76 2e-14
gi|4757902 caltractin [Homo sapiens] 76 2e-14
gi|21624641 calcium binding protein 4 [Homo sapiens] 74 1e-13
gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo... 73 2e-13
gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo... 73 2e-13
gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo ... 73 2e-13
gi|11067753 calcium binding protein 5 [Homo sapiens] 73 2e-13
gi|223278387 calmodulin-like 5 [Homo sapiens] 72 3e-13
gi|169167243 PREDICTED: similar to myosin regulatory light chain... 72 3e-13
gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo... 72 3e-13
gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [... 72 3e-13
gi|88981341 PREDICTED: similar to myosin regulatory light chain ... 72 4e-13
>gi|4505303 smooth muscle and non-muscle myosin alkali light chain
6B [Homo sapiens]
Length = 208
Score = 419 bits (1076), Expect = e-117
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE 60
MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE
Sbjct: 1 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE 60
Query: 61 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR 120
FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR
Sbjct: 61 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR 120
Query: 121 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE 180
RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE
Sbjct: 121 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE 180
Query: 181 EVETVLAGHEDSNGCINYEAFLKHILSV 208
EVETVLAGHEDSNGCINYEAFLKHILSV
Sbjct: 181 EVETVLAGHEDSNGCINYEAFLKHILSV 208
>gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f
[Homo sapiens]
Length = 194
Score = 259 bits (662), Expect = 1e-69
Identities = 130/208 (62%), Positives = 157/208 (75%), Gaps = 14/208 (6%)
Query: 1 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE 60
M PKKDV KKP + + PA PA A AP AP K +E +DLS + IE
Sbjct: 1 MAPKKDV--KKPVAAAAAAPAPAPAPAPAP------------APAKPKEEKIDLSAIKIE 46
Query: 61 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR 120
F+K+Q +EFKEAF LFDR GD KI SQ GDV+RALG NPTNAEV KVLGNP ++EL ++
Sbjct: 47 FSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK 106
Query: 121 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE 180
+++FE FLPM+QA++ N+ Q TYED++EG RVFDKEGNG VMGAELRHVL TLGEKM EE
Sbjct: 107 KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEE 166
Query: 181 EVETVLAGHEDSNGCINYEAFLKHILSV 208
EVE ++AG EDSNGCINYEAF+KHI+S+
Sbjct: 167 EVEALMAGQEDSNGCINYEAFVKHIMSI 194
>gi|17986258 myosin, light chain 6, alkali, smooth muscle and
non-muscle isoform 1 [Homo sapiens]
Length = 151
Score = 254 bits (649), Expect = 4e-68
Identities = 121/148 (81%), Positives = 134/148 (90%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+F +DQ EFKEAF+LFDR GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE+
Sbjct: 3 DFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNV 62
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+ +DFE FLPMLQ VAKN+ QGTYEDY+EG RVFDKEGNG VMGAE+RHVL TLGEKMTE
Sbjct: 63 KVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTE 122
Query: 180 EEVETVLAGHEDSNGCINYEAFLKHILS 207
EEVE ++AGHEDSNGCINYEAF++HILS
Sbjct: 123 EEVEMLVAGHEDSNGCINYEAFVRHILS 150
>gi|4557038 atrial/embryonic alkali myosin light chain [Homo
sapiens]
Length = 197
Score = 251 bits (641), Expect = 3e-67
Identities = 129/199 (64%), Positives = 151/199 (75%), Gaps = 8/199 (4%)
Query: 12 PAGPSISKPAAKPAAAGAP-PAKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFK 70
P P K AAKPA A AP PA PA AP+ +EP D V I+F DQ+EEFK
Sbjct: 3 PKKPEPKKEAAKPAPAPAPAPA-----PAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFK 57
Query: 71 EAFELFDRV--GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFL 128
EAF LFDR G+ KI Y QCGDV+RALGQNPTNAEVL+VLG PK +E+ + +DFETFL
Sbjct: 58 EAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFL 117
Query: 129 PMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAG 188
P+LQ +++N+ QGTYED++EG RVFDKE NG VMGAELRHVL TLGEKMTE EVE +LAG
Sbjct: 118 PILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAG 177
Query: 189 HEDSNGCINYEAFLKHILS 207
ED+NGCINYEAF+KHI+S
Sbjct: 178 QEDANGCINYEAFVKHIMS 196
>gi|50845428 atrial/embryonic alkali myosin light chain [Homo
sapiens]
Length = 197
Score = 251 bits (641), Expect = 3e-67
Identities = 129/199 (64%), Positives = 151/199 (75%), Gaps = 8/199 (4%)
Query: 12 PAGPSISKPAAKPAAAGAP-PAKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFK 70
P P K AAKPA A AP PA PA AP+ +EP D V I+F DQ+EEFK
Sbjct: 3 PKKPEPKKEAAKPAPAPAPAPA-----PAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFK 57
Query: 71 EAFELFDRV--GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFL 128
EAF LFDR G+ KI Y QCGDV+RALGQNPTNAEVL+VLG PK +E+ + +DFETFL
Sbjct: 58 EAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFL 117
Query: 129 PMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAG 188
P+LQ +++N+ QGTYED++EG RVFDKE NG VMGAELRHVL TLGEKMTE EVE +LAG
Sbjct: 118 PILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAG 177
Query: 189 HEDSNGCINYEAFLKHILS 207
ED+NGCINYEAF+KHI+S
Sbjct: 178 QEDANGCINYEAFVKHIMS 196
>gi|88999583 myosin, light chain 6, alkali, smooth muscle and
non-muscle isoform 2 [Homo sapiens]
Length = 151
Score = 244 bits (624), Expect = 3e-65
Identities = 116/148 (78%), Positives = 131/148 (88%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+F +DQ EFKEAF+LFDR GDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE+
Sbjct: 3 DFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNV 62
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+ +DFE FLPMLQ VAKN+ QGTYEDY+EG RVFDKEGNG VMGAE+RHVL TLGEKMTE
Sbjct: 63 KVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTE 122
Query: 180 EEVETVLAGHEDSNGCINYEAFLKHILS 207
EEVE ++AGHEDSNGCINYE ++ +L+
Sbjct: 123 EEVEMLVAGHEDSNGCINYEELVRMVLN 150
>gi|4557777 slow skeletal ventricular myosin alkali light chain 3
[Homo sapiens]
Length = 195
Score = 244 bits (622), Expect = 5e-65
Identities = 122/198 (61%), Positives = 148/198 (74%), Gaps = 8/198 (4%)
Query: 12 PAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKE 71
P P K AK A AP PA P P++ +E D SK+ IEF +Q+EEFKE
Sbjct: 3 PKKPEPKKDDAKAAPKAAPA------PAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKE 56
Query: 72 AFELFDRVG--DGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLP 129
AF LFDR + KI Y QCGDV+RALGQNPT AEVL+VLG P+ +EL ++ +DFETFLP
Sbjct: 57 AFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLP 116
Query: 130 MLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGH 189
MLQ ++KN+ GTYED++EG RVFDKEGNG VMGAELRHVL TLGE++TE+EVE ++AG
Sbjct: 117 MLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQ 176
Query: 190 EDSNGCINYEAFLKHILS 207
EDSNGCINYEAF+KHI+S
Sbjct: 177 EDSNGCINYEAFVKHIMS 194
>gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f
[Homo sapiens]
Length = 150
Score = 226 bits (575), Expect = 1e-59
Identities = 105/150 (70%), Positives = 127/150 (84%)
Query: 59 IEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELK 118
+ F+ DQ+ EFKEAF LFDR GD KI SQ GDV+RALG NPTNAEV KVLGNP ++EL
Sbjct: 1 MSFSADQIAEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELN 60
Query: 119 SRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMT 178
+++++FE FLPM+QA++ N+ Q TYED++EG RVFDKEGNG VMGAELRHVL TLGEKM
Sbjct: 61 AKKIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMK 120
Query: 179 EEEVETVLAGHEDSNGCINYEAFLKHILSV 208
EEEVE ++AG EDSNGCINYEAF+KHI+S+
Sbjct: 121 EEEVEALMAGQEDSNGCINYEAFVKHIMSI 150
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 124 bits (310), Expect = 7e-29
Identities = 65/145 (44%), Positives = 95/145 (65%), Gaps = 5/145 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+ ++Q+ EFKEAF LFD+ GDG I + G VMR+LGQNPT AE+ ++ +D +
Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG--N 61
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+DF FL M+ K + + E+ E FRVFDK+GNG + AELRHV+T LGEK+T+
Sbjct: 62 GTIDFPEFLTMM--ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 119
Query: 180 EEVETVLAGHE-DSNGCINYEAFLK 203
EEV+ ++ + D +G +NYE F++
Sbjct: 120 EEVDEMIREADIDGDGQVNYEEFVQ 144
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 124 bits (310), Expect = 7e-29
Identities = 65/145 (44%), Positives = 95/145 (65%), Gaps = 5/145 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+ ++Q+ EFKEAF LFD+ GDG I + G VMR+LGQNPT AE+ ++ +D +
Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG--N 61
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+DF FL M+ K + + E+ E FRVFDK+GNG + AELRHV+T LGEK+T+
Sbjct: 62 GTIDFPEFLTMM--ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 119
Query: 180 EEVETVLAGHE-DSNGCINYEAFLK 203
EEV+ ++ + D +G +NYE F++
Sbjct: 120 EEVDEMIREADIDGDGQVNYEEFVQ 144
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 124 bits (310), Expect = 7e-29
Identities = 65/145 (44%), Positives = 95/145 (65%), Gaps = 5/145 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+ ++Q+ EFKEAF LFD+ GDG I + G VMR+LGQNPT AE+ ++ +D +
Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG--N 61
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+DF FL M+ K + + E+ E FRVFDK+GNG + AELRHV+T LGEK+T+
Sbjct: 62 GTIDFPEFLTMM--ARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTD 119
Query: 180 EEVETVLAGHE-DSNGCINYEAFLK 203
EEV+ ++ + D +G +NYE F++
Sbjct: 120 EEVDEMIREADIDGDGQVNYEEFVQ 144
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 123 bits (308), Expect = 1e-28
Identities = 69/149 (46%), Positives = 95/149 (63%), Gaps = 5/149 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
+ ++Q+ EFKEAF LFD+ GDG I + G VMR+LGQNPT AE+ ++ D +
Sbjct: 4 QLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDG--N 61
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
VDF FL M+ K + E+ E FRVFDK+GNG V AELRHV+T LGEK+++
Sbjct: 62 GTVDFPEFLGMM--ARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSD 119
Query: 180 EEV-ETVLAGHEDSNGCINYEAFLKHILS 207
EEV E + A D +G +NYE F++ ++S
Sbjct: 120 EEVDEMIRAADTDGDGQVNYEEFVRVLVS 148
>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
Length = 160
Score = 93.2 bits (230), Expect = 1e-19
Identities = 53/144 (36%), Positives = 86/144 (59%), Gaps = 4/144 (2%)
Query: 62 NKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRR 121
+++ + EFK AF++FD G G I + G VMR LGQ PT E+ ++ + DE S
Sbjct: 13 SEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAII--EEVDEDGSGT 70
Query: 122 VDFETFLPMLQAVAKNRGQGTYEDYL-EGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE 180
+DFE FL M+ K +G E+ L E FR+FD+ +G + EL + GE +T+E
Sbjct: 71 IDFEEFLVMMVRQMKEDAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHVTDE 130
Query: 181 EVETVLA-GHEDSNGCINYEAFLK 203
E+E+++ G ++++G I+++ FLK
Sbjct: 131 EIESLMKDGDKNNDGRIDFDEFLK 154
>gi|4507615 troponin C, slow [Homo sapiens]
Length = 161
Score = 87.8 bits (216), Expect = 6e-18
Identities = 58/160 (36%), Positives = 94/160 (58%), Gaps = 6/160 (3%)
Query: 53 DLSKVVIE-FNKDQLEEFKEAFELFDR-VGDGKILYSQCGDVMRALGQNPTNAEVLKVLG 110
D+ K +E ++Q EFK AF++F DG I + G VMR LGQNPT E+ +++
Sbjct: 3 DIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMID 62
Query: 111 NPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEG-FRVFDKEGNGKVMGAELRHV 169
+ DE S VDF+ FL M+ K+ +G E+ L FR+FDK +G + EL+ +
Sbjct: 63 --EVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIM 120
Query: 170 LTTLGEKMTEEEVETVLA-GHEDSNGCINYEAFLKHILSV 208
L GE +TE+++E ++ G ++++G I+Y+ FL+ + V
Sbjct: 121 LQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGV 160
>gi|4757974 centrin 1 [Homo sapiens]
Length = 172
Score = 80.9 bits (198), Expect = 7e-16
Identities = 49/145 (33%), Positives = 79/145 (54%), Gaps = 5/145 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
E +DQ +E +EAF+LFD G G I + MRALG P E+ K++ + D +
Sbjct: 24 ELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMIS--EVDREGT 81
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
++ F FL ++ K + T E+ L+ FR+FD + GK+ L+ V LGE +T+
Sbjct: 82 GKISFNDFLAVM--TQKMSEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTD 139
Query: 180 EEVETVL-AGHEDSNGCINYEAFLK 203
EE++ ++ D +G +N E FL+
Sbjct: 140 EELQEMIDEADRDGDGEVNEEEFLR 164
>gi|110227594 calmodulin-like 4 isoform 1 [Homo sapiens]
Length = 196
Score = 79.0 bits (193), Expect = 3e-15
Identities = 50/145 (34%), Positives = 79/145 (54%), Gaps = 5/145 (3%)
Query: 62 NKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRR 121
++DQ+ E+KE F L+D+ GKI + MR LG +PT EV + L D +
Sbjct: 49 SQDQINEYKECFSLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGID--GNGE 106
Query: 122 VDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEE 181
+DF TFL ++ K + ++ L + DKE G VM ++LR LT+LGEK+T +E
Sbjct: 107 LDFSTFLTIMHMQIKQ--EDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEKLTHKE 164
Query: 182 VETVLAGHE-DSNGCINYEAFLKHI 205
V+ + + + NG + Y+ F+ I
Sbjct: 165 VDDLFREADIEPNGKVKYDEFIHKI 189
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 134 VAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHE-DS 192
+AK Q +Y E F ++DK+ GK+ +L + LG T EV+ L H D
Sbjct: 44 MAKFLSQDQINEYKECFSLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGIDG 103
Query: 193 NGCINYEAFL 202
NG +++ FL
Sbjct: 104 NGELDFSTFL 113
>gi|46397403 centrin 3 [Homo sapiens]
Length = 167
Score = 78.2 bits (191), Expect = 5e-15
Identities = 50/144 (34%), Positives = 81/144 (56%), Gaps = 5/144 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
E +++Q +E K+AFELFD D I Y + MRALG + A+VLK+L + D +
Sbjct: 21 ELSEEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKD--YDREAT 78
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
++ FE F ++ R +E+ L+ F++FD + +GK+ LR V LGE M++
Sbjct: 79 GKITFEDFNEVVTDWILER--DPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSD 136
Query: 180 EEVETVLAGHE-DSNGCINYEAFL 202
EE+ ++ + D +G IN E F+
Sbjct: 137 EELRAMIEEFDKDGDGEINQEEFI 160
>gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]
Length = 220
Score = 77.4 bits (189), Expect = 8e-15
Identities = 46/158 (29%), Positives = 88/158 (55%), Gaps = 9/158 (5%)
Query: 50 PPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVL 109
P + +++ E +++EE + AF+ FDR DG I + G MR LG PT E++++
Sbjct: 64 PSIAATQLDRELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEI- 122
Query: 110 GNPKSDELKSRRVDFETFLPML--QAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELR 167
S ++ +VDFE F+ ++ + +A+ + + FR FD G+G++ ELR
Sbjct: 123 ----SQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELR 178
Query: 168 HVL-TTLGEKMTEEEVETVLAGHE-DSNGCINYEAFLK 203
L LGE++++ EV+ +L + + +G +++E F++
Sbjct: 179 AALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVR 216
>gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]
Length = 163
Score = 76.3 bits (186), Expect = 2e-14
Identities = 45/148 (30%), Positives = 83/148 (56%), Gaps = 9/148 (6%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
E +++EE + AF+ FDR DG I + G MR LG PT E++++ S ++
Sbjct: 17 ELRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMELIEI-----SQQISG 71
Query: 120 RRVDFETFLPML--QAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVL-TTLGEK 176
+VDFE F+ ++ + +A+ + + FR FD G+G++ ELR L LGE+
Sbjct: 72 GKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKALLGER 131
Query: 177 MTEEEVETVLAGHE-DSNGCINYEAFLK 203
+++ EV+ +L + + +G +++E F++
Sbjct: 132 LSQREVDEILQDVDLNGDGLVDFEEFVR 159
>gi|4757902 caltractin [Homo sapiens]
Length = 172
Score = 75.9 bits (185), Expect = 2e-14
Identities = 45/145 (31%), Positives = 81/145 (55%), Gaps = 5/145 (3%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
E ++Q +E +EAF+LFD G G I + MRALG P E+ K++ + D+ +
Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMIS--EIDKEGT 81
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+++F FL ++ K + T E+ L+ F++FD + GK+ L+ V LGE +T+
Sbjct: 82 GKMNFGDFLTVM--TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 139
Query: 180 EEVETVL-AGHEDSNGCINYEAFLK 203
EE++ ++ D +G ++ + FL+
Sbjct: 140 EELQEMIDEADRDGDGEVSEQEFLR 164
>gi|21624641 calcium binding protein 4 [Homo sapiens]
Length = 275
Score = 73.6 bits (179), Expect = 1e-13
Identities = 62/211 (29%), Positives = 102/211 (48%), Gaps = 18/211 (8%)
Query: 2 PPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVV--- 58
P + P GP+ P A P A + + ++ A Q+T P L++V
Sbjct: 67 PGSSNNPPSTGEGPA-GAPPASPGPASSRQSHRHRPDSLHDAAQRTYGPL--LNRVFGKD 123
Query: 59 IEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELK 118
E ++L+E + AFE FD DG I + + GD MR LG PT E+L+V S +K
Sbjct: 124 RELGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELLEV-----SQHIK 178
Query: 119 SR---RVDFETFLPMLQAVAKNRGQGT--YEDYLEGFRVFDKEGNGKVMGAELRH-VLTT 172
R RVDFE F+ ++ + + FR FD++ +G++ AELR V
Sbjct: 179 MRMGGRVDFEEFVELIGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPAL 238
Query: 173 LGEKMTEEEVETVLAGHE-DSNGCINYEAFL 202
LGE + E++ +L + + +G ++++ F+
Sbjct: 239 LGEPLAGPELDEMLREVDLNGDGTVDFDEFV 269
>gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 73.2 bits (178), Expect = 2e-13
Identities = 57/177 (32%), Positives = 81/177 (45%), Gaps = 21/177 (11%)
Query: 32 AKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGD 91
AKTK PQ S V F++ Q++EFKEAF + D+ DG I D
Sbjct: 6 AKTKTTKKRPQRAT---------SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 92 VMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFR 151
++ +LG+NPT+A + ++ ++F FL M K G + F
Sbjct: 57 MLASLGKNPTDAYLDAMMNEAPGP------INFTMFLTMFG--EKLNGTDPEDVIRNAFA 108
Query: 152 VFDKEGNGKVMGAELRHVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
FD+E G + LR +LTT+G++ T+EEV E D G NY F LKH
Sbjct: 109 CFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 165
>gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 73.2 bits (178), Expect = 2e-13
Identities = 57/177 (32%), Positives = 81/177 (45%), Gaps = 21/177 (11%)
Query: 32 AKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGD 91
AKTK PQ S V F++ Q++EFKEAF + D+ DG I D
Sbjct: 6 AKTKTTKKRPQRAT---------SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 92 VMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFR 151
++ +LG+NPT+A + ++ ++F FL M K G + F
Sbjct: 57 MLASLGKNPTDAYLDAMMNEAPGP------INFTMFLTMFG--EKLNGTDPEDVIRNAFA 108
Query: 152 VFDKEGNGKVMGAELRHVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
FD+E G + LR +LTT+G++ T+EEV E D G NY F LKH
Sbjct: 109 CFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 165
>gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo
sapiens]
Length = 172
Score = 73.2 bits (178), Expect = 2e-13
Identities = 57/177 (32%), Positives = 81/177 (45%), Gaps = 21/177 (11%)
Query: 32 AKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGD 91
AKTK PQ S V F++ Q++EFKEAF + D+ DG I D
Sbjct: 6 AKTKTTKKRPQRAT---------SNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHD 56
Query: 92 VMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFR 151
++ +LG+NPT+A + ++ ++F FL M K G + F
Sbjct: 57 MLASLGKNPTDAYLDAMMNEAPGP------INFTMFLTMFG--EKLNGTDPEDVIRNAFA 108
Query: 152 VFDKEGNGKVMGAELRHVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
FD+E G + LR +LTT+G++ T+EEV E D G NY F LKH
Sbjct: 109 CFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 165
>gi|11067753 calcium binding protein 5 [Homo sapiens]
Length = 173
Score = 72.8 bits (177), Expect = 2e-13
Identities = 46/145 (31%), Positives = 82/145 (56%), Gaps = 6/145 (4%)
Query: 63 KDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRV 122
+D++EE +EAF FD+ DG I G++MR +G PT E+++ LG L RV
Sbjct: 27 QDEIEELREAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMELIE-LGQQIRMNL-GGRV 84
Query: 123 DFETFLPML--QAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVL-TTLGEKMTE 179
DF+ F+ ++ + +A+ G ++ + F+ FD G+G++ EL+ + LGE++T
Sbjct: 85 DFDDFVELMTPKLLAETAGMIGVQEMRDAFKEFDTNGDGEITLVELQQAMQRLLGERLTP 144
Query: 180 EEV-ETVLAGHEDSNGCINYEAFLK 203
E+ E V + +G +++E F+K
Sbjct: 145 REISEVVREADVNGDGTVDFEEFVK 169
Score = 30.4 bits (67), Expect = 1.1
Identities = 15/44 (34%), Positives = 25/44 (56%)
Query: 139 GQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEV 182
GQ E+ E F FDK+ +G + +L +++ T+G TE E+
Sbjct: 26 GQDEIEELREAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMEL 69
>gi|223278387 calmodulin-like 5 [Homo sapiens]
Length = 146
Score = 72.4 bits (176), Expect = 3e-13
Identities = 41/145 (28%), Positives = 76/145 (52%), Gaps = 8/145 (5%)
Query: 60 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 119
E ++ ++K+AF D G+G I + G ++A G+N + A++ K++ SD
Sbjct: 4 ELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG--D 61
Query: 120 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTE 179
+ F+ FL A + + ED FR FD++G+G + ELR + LG+ + +
Sbjct: 62 GEISFQEFL-----TAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQ 116
Query: 180 EEVETVLAGHE-DSNGCINYEAFLK 203
EE++ ++ + D +G +NYE F +
Sbjct: 117 EELDAMIREADVDQDGRVNYEEFAR 141
>gi|169167243 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 72.0 bits (175), Expect = 3e-13
Identities = 52/161 (32%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query: 48 QEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLK 107
+ P SKV F++ Q++EFKEAF + D+ DG I ++ +LG+NPT+A +
Sbjct: 218 KRPQCATSKVFATFDQSQIQEFKEAFNMIDQNRDGFISKEDLHGMLASLGKNPTDACLDA 277
Query: 108 VLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELR 167
V+ ++F L M K G + F FD+E G + LR
Sbjct: 278 VMNEAPGP------INFTMLLAMFG--KKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 329
Query: 168 HVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
+LTT+G++ T+EEV E D G NY F LKH
Sbjct: 330 ELLTTVGDQFTDEEVDELYTEASIDKKGNFNYIEFTSILKH 370
>gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo
sapiens]
Length = 154
Score = 72.0 bits (175), Expect = 3e-13
Identities = 50/155 (32%), Positives = 76/155 (49%), Gaps = 12/155 (7%)
Query: 54 LSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPK 113
+S + F++ Q++EFKEAF + D+ DG I D++ +LG+NPT+A + ++
Sbjct: 1 MSSMFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAP 60
Query: 114 SDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTL 173
++F FL M K G + F FD+E G + LR +LTT+
Sbjct: 61 GP------INFTMFLTMFG--EKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTM 112
Query: 174 GEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
G++ T+EEV E D G NY F LKH
Sbjct: 113 GDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 147
>gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric
[Homo sapiens]
Length = 171
Score = 72.0 bits (175), Expect = 3e-13
Identities = 54/161 (33%), Positives = 77/161 (47%), Gaps = 12/161 (7%)
Query: 48 QEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLK 107
+ P S V F++ Q++EFKEAF + D+ DG I D++ +LG+NPT+ E L
Sbjct: 12 KRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTD-EYLD 70
Query: 108 VLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELR 167
+ N ++F FL M K G + F FD+E G + LR
Sbjct: 71 AMMNEAPGP-----INFTMFLTMFG--EKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 123
Query: 168 HVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
+LTT+G++ T+EEV E D G NY F LKH
Sbjct: 124 ELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKH 164
>gi|88981341 PREDICTED: similar to myosin regulatory light chain
MRCL2 [Homo sapiens]
Length = 377
Score = 71.6 bits (174), Expect = 4e-13
Identities = 52/161 (32%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query: 48 QEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLK 107
+ P SKV F++ Q++EFKEAF + D+ DG I ++ +LG+NPT+A +
Sbjct: 218 KRPQCATSKVFATFDQSQIQEFKEAFNMIDQNRDGFISKEDLHGMLASLGKNPTDACLDA 277
Query: 108 VLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELR 167
V+ ++F L M K G + F FD+E G + LR
Sbjct: 278 VMNEAPGP------INFTMLLAMFG--KKLNGTDPEDVIRNAFACFDEEATGTIQEDYLR 329
Query: 168 HVLTTLGEKMTEEEV-ETVLAGHEDSNGCINYEAF---LKH 204
+LTT+G++ T+EEV E D G NY F LKH
Sbjct: 330 ELLTTVGDQFTDEEVDELYTEAPIDKKGNFNYIEFTSILKH 370
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,925,755
Number of Sequences: 37866
Number of extensions: 434179
Number of successful extensions: 4714
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 194
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 3547
Number of HSP's gapped (non-prelim): 1246
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.