BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4504927 keratin 36 [Homo sapiens] (467 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4504927 keratin 36 [Homo sapiens] 931 0.0 gi|94538345 keratin 35 [Homo sapiens] 599 e-171 gi|116488398 keratin 32 [Homo sapiens] 563 e-160 gi|14917115 keratin 31 [Homo sapiens] 551 e-157 gi|14917117 keratin 33A [Homo sapiens] 534 e-152 gi|10337581 type I hair keratin 3B [Homo sapiens] 528 e-150 gi|14917119 keratin 34 [Homo sapiens] 523 e-148 gi|125490370 type I hair keratin KA36 [Homo sapiens] 495 e-140 gi|148277620 type I hair keratin KA35 [Homo sapiens] 491 e-139 gi|15431318 keratin 38 [Homo sapiens] 461 e-130 gi|55770882 keratin 37 [Homo sapiens] 449 e-126 gi|15431310 keratin 14 [Homo sapiens] 444 e-125 gi|4557701 keratin 17 [Homo sapiens] 432 e-121 gi|24430192 keratin 16 [Homo sapiens] 432 e-121 gi|24430190 keratin 15 [Homo sapiens] 400 e-111 gi|24234699 keratin 19 [Homo sapiens] 395 e-110 gi|131412225 keratin 13 isoform a [Homo sapiens] 377 e-104 gi|131412228 keratin 13 isoform b [Homo sapiens] 377 e-104 gi|195972866 keratin 10 [Homo sapiens] 359 3e-99 gi|4557699 keratin 12 [Homo sapiens] 350 2e-96 gi|114431246 keratin 25D [Homo sapiens] 343 1e-94 gi|27894337 keratin 20 [Homo sapiens] 342 4e-94 gi|153945736 keratin 27 [Homo sapiens] 340 2e-93 gi|192807292 keratin 24 [Homo sapiens] 331 1e-90 gi|31559829 keratin 25 [Homo sapiens] 328 6e-90 gi|40354195 keratin 18 [Homo sapiens] 313 3e-85 gi|4557888 keratin 18 [Homo sapiens] 313 3e-85 gi|55956899 keratin 9 [Homo sapiens] 303 3e-82 gi|31559815 keratin 26 [Homo sapiens] 298 7e-81 gi|27894339 keratin 23 [Homo sapiens] 289 4e-78 >gi|4504927 keratin 36 [Homo sapiens] Length = 467 Score = 931 bits (2406), Expect = 0.0 Identities = 467/467 (100%), Positives = 467/467 (100%) Query: 1 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLG 60 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLG Sbjct: 1 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLG 60 Query: 61 SCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAE 120 SCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAE Sbjct: 61 SCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAE 120 Query: 121 LESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRT 180 LESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRT Sbjct: 121 LESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRT 180 Query: 181 KYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRC 240 KYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRC Sbjct: 181 KYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRC 240 Query: 241 QLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSE 300 QLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSE Sbjct: 241 QLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSE 300 Query: 301 QLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEA 360 QLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEA Sbjct: 301 QLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEA 360 Query: 361 QLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVP 420 QLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVP Sbjct: 361 QLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVP 420 Query: 421 SVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL 467 SVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL Sbjct: 421 SVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL 467 >gi|94538345 keratin 35 [Homo sapiens] Length = 455 Score = 599 bits (1545), Expect = e-171 Identities = 310/440 (70%), Positives = 358/440 (81%), Gaps = 9/440 (2%) Query: 1 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLG 60 MA++ FS+GS+K G +GG +RVS++ S SC++PSL+ A S+ GL Sbjct: 1 MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60 Query: 61 ----SCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLER 116 SCLP L + + + G GGWF EG G+EKETMQ LNDRLA YLEKVRQLE+ Sbjct: 61 YRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQ 120 Query: 117 ENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAAD 176 ENA LESRI+EW E Q+PY+CPDYQSYF+TIE+ Q+K L +K+ENARLV++IDNAKLAAD Sbjct: 121 ENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAAD 180 Query: 177 DFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVS 236 DFRTKYETE+SLRQLVE+DINGLRRILD+LTLCK+DLEAQVESLKEEL+CLKKNHEEEV+ Sbjct: 181 DFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVN 240 Query: 237 VLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVV 296 LRCQLGDRLNVEVDAAPPVDLN++LE+MRCQYE LVENNRRD E W +TQ+EELNQQVV Sbjct: 241 SLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVV 300 Query: 297 SSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLIS 356 SSSEQLQ CQ EIIELRRTVNALEIELQAQHSMR++LESTLAETEARYSSQLAQMQC+I+ Sbjct: 301 SSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMIT 360 Query: 357 NVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPV 416 NVEAQL+EIR DLERQNQEYQVLLDV+ARLE EI TYR LLE ED KLP PCA Sbjct: 361 NVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCAPDYS-- 418 Query: 417 IRVPSVPPVPCVPSVPCTPA 436 PS +PC+P+ C P+ Sbjct: 419 ---PSKSCLPCLPAASCGPS 435 >gi|116488398 keratin 32 [Homo sapiens] Length = 448 Score = 563 bits (1451), Expect = e-160 Identities = 286/386 (74%), Positives = 327/386 (84%), Gaps = 8/386 (2%) Query: 61 SCLPGSYLSSECHT----SGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLER 116 SCL +YLSS C SG +G G W+ EG+FNG+EKETMQFLNDRLA+YL +VRQLE+ Sbjct: 60 SCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQ 119 Query: 117 ENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAAD 176 ENAELESRIQE Q+ + PDYQS+F+TIE+ QQKIL TK+ENAR+V+ IDNAKLAAD Sbjct: 120 ENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAAD 179 Query: 177 DFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVS 236 DFR KYE EL++RQLVEADINGLRRILD+LTLCKADLEAQVESLKEELMCLKKNHEEEV Sbjct: 180 DFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVG 239 Query: 237 VLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVV 296 LRCQLGDRLN+EVDAAPPVDL ++LE+MRCQYEA+VE NRRDVE WFN Q EELNQQV Sbjct: 240 SLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVA 299 Query: 297 SSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLIS 356 +SSEQLQ Q++II+LRRTVN LEIELQAQHS+R+SLE+TL E+EARYSSQLAQMQC+I+ Sbjct: 300 TSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMIT 359 Query: 357 NVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCAT-ACKP 415 NVEAQL+EIR DLERQNQEYQVLLDV+ARLEGEI TYR LLE EDCKLP PC+T +C Sbjct: 360 NVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTT 419 Query: 416 VIRVPSVPPVPCVP---SVPCTPAPQ 438 + P VP CVP +PC+P PQ Sbjct: 420 CVPSPCVPRTVCVPRTVGMPCSPCPQ 445 >gi|14917115 keratin 31 [Homo sapiens] Length = 416 Score = 551 bits (1420), Expect = e-157 Identities = 287/381 (75%), Positives = 321/381 (84%), Gaps = 7/381 (1%) Query: 62 CLPGSY----LSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERE 117 C+P S L C+ V + WFCEGSFNGSEKETMQFLNDRLA+YLEKVRQLER+ Sbjct: 21 CVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERD 80 Query: 118 NAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADD 177 NAELE+ I+E + Q P +CP YQSYFKTIE+ QQKIL TKSENARLV+QIDNAKLAADD Sbjct: 81 NAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADD 140 Query: 178 FRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSV 237 FRTKY+TELSLRQLVE+DINGLRRILDELTLCK+DLEAQVESLKEEL+CLK NHE+EV+ Sbjct: 141 FRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNT 200 Query: 238 LRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVS 297 LRCQLGDRLNVEVDAAP VDLN++L + R QYEALVE NRR+VE WF TQTEELN+QVVS Sbjct: 201 LRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVS 260 Query: 298 SSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISN 357 SSEQLQ Q EIIELRRTVNALEIELQAQH++R+SLE+TL E+EARYSSQL+Q+Q LI+N Sbjct: 261 SSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITN 320 Query: 358 VEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCAT--AC-K 414 VE+QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR LLE EDC LP PCAT AC K Sbjct: 321 VESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSK 380 Query: 415 PVIRVPSVPPVPCVPSVPCTP 435 P+ S P CVP PCTP Sbjct: 381 PIGPCLSNPCTSCVPPAPCTP 401 >gi|14917117 keratin 33A [Homo sapiens] Length = 404 Score = 534 bits (1375), Expect = e-152 Identities = 279/376 (74%), Positives = 317/376 (84%), Gaps = 5/376 (1%) Query: 36 SCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKE 95 SC +PSL+ S S G LPG+ C+ V + WFCEGSFNGSEKE Sbjct: 4 SCGLPSLSCRTSCSSRPCVPPSCHGCTLPGA-----CNIPANVSNCNWFCEGSFNGSEKE 58 Query: 96 TMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKIL 155 TMQFLNDRLA+YLEKVRQLER+NAELE+ I+E + Q P +C YQSYFKTIE+ QQKIL Sbjct: 59 TMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKIL 118 Query: 156 LTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEA 215 +KSENARLV+QIDNAKLA+DDFRTKYETELSLRQLVE+DINGLRRILDELTLC++DLEA Sbjct: 119 CSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEA 178 Query: 216 QVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVEN 275 QVESLKEEL+CLK+NHE+EV+ LRCQLGDRLNVEVDAAP VDLN++L + R QYEALVE Sbjct: 179 QVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVET 238 Query: 276 NRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLES 335 NRR+VE WF TQTEELN+QVVSSSEQLQ Q EIIELRRTVNALEIELQAQH++R+SLE+ Sbjct: 239 NRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLEN 298 Query: 336 TLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRH 395 TL E+EARYSSQL+Q+Q LI+NVE+QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR Sbjct: 299 TLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRS 358 Query: 396 LLEGEDCKLPPQPCAT 411 LLE EDCKLP PCAT Sbjct: 359 LLESEDCKLPSNPCAT 374 >gi|10337581 type I hair keratin 3B [Homo sapiens] Length = 404 Score = 528 bits (1359), Expect = e-150 Identities = 276/383 (72%), Positives = 313/383 (81%), Gaps = 4/383 (1%) Query: 62 CLP----GSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERE 117 C+P G L C+ V + WFCEGSFNGSEKETMQFLNDRLA+YLEKVRQLER+ Sbjct: 21 CVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERD 80 Query: 118 NAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADD 177 NAELE+ I+E + Q P +CP YQSYFKTIE+ QQKIL +KSENARLV+QIDNAKLAADD Sbjct: 81 NAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAADD 140 Query: 178 FRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSV 237 FRTKY+TE SLRQLVE+DIN LRRILDELTLC++DLEAQ+ESLKEEL+ LK+NHE+EV+ Sbjct: 141 FRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNT 200 Query: 238 LRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVS 297 LRCQLGDRLNVEVDAAP VDLN++L + R QYEALVE NRR+VE WF TQTEELN+QVVS Sbjct: 201 LRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVVS 260 Query: 298 SSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISN 357 SSEQLQ Q EIIELRRTVNALEIELQAQH++R SLE+TL E+EARYSSQL+Q+Q LI+N Sbjct: 261 SSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLITN 320 Query: 358 VEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVI 417 VE+QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR LLE EDCKLP PCAT Sbjct: 321 VESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACEK 380 Query: 418 RVPSVPPVPCVPSVPCTPAPQVG 440 + S PC P C P G Sbjct: 381 PIGSCVTNPCGPRSRCGPCNTFG 403 >gi|14917119 keratin 34 [Homo sapiens] Length = 436 Score = 523 bits (1347), Expect = e-148 Identities = 273/376 (72%), Positives = 310/376 (82%), Gaps = 5/376 (1%) Query: 36 SCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKE 95 SC +PSL S S G LPG+ C+ V + WFCEGSFNGSEKE Sbjct: 46 SCCLPSLGCRTSCSSRPCVPPSCHGYTLPGA-----CNIPANVSNCNWFCEGSFNGSEKE 100 Query: 96 TMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKIL 155 TMQFLNDRLA+YLEKVRQLER+NAELE IQE + Q P +CP YQSYFKTIE+ QQKIL Sbjct: 101 TMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKIL 160 Query: 156 LTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEA 215 K+ENARLV+ IDNAKLA+DDFR+KY+TE SLR LVE+DIN +RRILDELTLCK+DLE+ Sbjct: 161 CAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLES 220 Query: 216 QVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVEN 275 QVESL+EEL+CLKKNHEEEV+ LR QLGDRLNVEVD AP VDLN++L + R QYEALVE Sbjct: 221 QVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEI 280 Query: 276 NRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLES 335 NRR+VE WF TQTEELN+QVVSSSEQLQ CQ EIIELRRTVNALEIELQAQH++R+SLE+ Sbjct: 281 NRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLEN 340 Query: 336 TLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRH 395 TL E+EA YSSQL+Q+Q LI+NVE+QL+EIRCDLERQNQEYQVLLDV+ARLE EI TYR Sbjct: 341 TLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRS 400 Query: 396 LLEGEDCKLPPQPCAT 411 LLE EDCKLP PCAT Sbjct: 401 LLESEDCKLPCNPCAT 416 >gi|125490370 type I hair keratin KA36 [Homo sapiens] Length = 431 Score = 495 bits (1274), Expect = e-140 Identities = 259/416 (62%), Positives = 310/416 (74%), Gaps = 5/416 (1%) Query: 19 CGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFV 78 CGTA G + SS +C + A + S S GL CL Y + C++ V Sbjct: 15 CGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLV 74 Query: 79 GSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP 138 G+ W +G F +EKETMQFLNDRLA+YLEKVR LE NAELESRIQE E IP +CP Sbjct: 75 GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP 134 Query: 139 DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADING 198 DYQ YF TIED QQKIL TK+EN+RL +Q+DN KLA DDF++KYE+ELSLRQL+EADI+ Sbjct: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194 Query: 199 LRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDL 258 L IL+ELTLCK+DLEA VESLKE+L+CLKKNHEEEV++LR QLGDRL+VE+D AP +DL Sbjct: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254 Query: 259 NKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNA 318 N++L++MRCQ E ++ NNRR+ E W QTEELNQQ +SS+EQLQ CQ EI+EL+RT +A Sbjct: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314 Query: 319 LEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQV 378 LEIELQAQ S+ SLE T+AETEA+YSSQLAQ+QCLI N+E QL+EIRCDLERQNQEYQV Sbjct: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374 Query: 379 LLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCT 434 LLDVKARLEGEI TY LL+ ED +L PC+T C S PC V CT Sbjct: 375 LLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTC-----TSSNTCEPCSAYVICT 425 >gi|148277620 type I hair keratin KA35 [Homo sapiens] Length = 491 Score = 491 bits (1263), Expect = e-139 Identities = 273/486 (56%), Positives = 335/486 (68%), Gaps = 28/486 (5%) Query: 1 MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSL-------AGAAGYISSAR 53 M T+ CT T S + C I+ VS+I S C L AG I + Sbjct: 1 MDTKGCTTTNSPSTP---CQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQ 57 Query: 54 SGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQ 113 C YL + + + W+ EG N +EKETMQ LN+RLANYL+KVR Sbjct: 58 GCQPTPRFCRKPIYLMNNFNARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRM 116 Query: 114 LERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKL 173 LERENAELES+IQE ++P +CPDY SY+ TIE+ QQKIL TK+EN+RLV QIDN KL Sbjct: 117 LERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKL 176 Query: 174 AADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEE 233 ADD R KYE E+SLRQLVE+D NGL++IL+ LTL KADLEAQV+SLKEEL+CLK NH+E Sbjct: 177 TADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKE 236 Query: 234 EVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQ 293 E++ L+CQLG+RL++EV AAP DLN++L++MRCQYE ++E NR+DVE WFNTQ EELNQ Sbjct: 237 EINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQ 296 Query: 294 QVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQC 353 QVV+SS+Q QCCQ EIIELRR+VN LE+ELQAQH MR+S E L ETEARY++ L Q+Q Sbjct: 297 QVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQS 356 Query: 354 LISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATAC 413 LI N+EAQL+EIRC LERQNQEY++LLDVK+RLE EI TYR LLE D K P P AT C Sbjct: 357 LIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKC 416 Query: 414 KPVI-------RVPSVPPVPCVPSVPCT---------PAPQVGTQIRTITEEIRDGKVIS 457 +P + S P C S PC+ P ++ +I TIT+EI+DGKVIS Sbjct: 417 EPSPWTSCKSGAIESTAPA-CTSSSPCSLKEHCSACGPLSRILVKICTITKEIKDGKVIS 475 Query: 458 SREHVQ 463 S EHVQ Sbjct: 476 SYEHVQ 481 >gi|15431318 keratin 38 [Homo sapiens] Length = 456 Score = 461 bits (1185), Expect = e-130 Identities = 250/450 (55%), Positives = 312/450 (69%), Gaps = 23/450 (5%) Query: 7 TPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAA--------GYISSARSGLSG 58 T ++S+ S C A G VS C+ + A A + + R G + Sbjct: 2 TSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGSTP 61 Query: 59 LGS---CLPGSY-----LSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEK 110 LG CLP + L CH G +G G + E + NG EKETMQFLNDRLANYLEK Sbjct: 62 LGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEK 121 Query: 111 VRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDN 170 VRQLE+ENAELE+ + E + +CPDYQSYF TIE+ QQKIL +K+ENARL++QIDN Sbjct: 122 VRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDN 181 Query: 171 AKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKN 230 AKLAADDFR K E+E SLRQLVEAD G +++LD+ TL KADLEAQ ESLKEE + LK N Sbjct: 182 AKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSN 241 Query: 231 HEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEE 290 HE+EV +LR QLG++L +E+D P +DLN++L +MR QYEA++E NR+DVE WF Q+E Sbjct: 242 HEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEG 301 Query: 291 LNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQ 350 ++ Q +S SE+LQCCQ+EI+ELR TVNALE+E QAQH++++ L+++L E E R+ ++LAQ Sbjct: 302 ISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQ 361 Query: 351 MQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCA 410 MQ LISNVE QLSEIR DLERQNQEYQVLLDVK RLE EIATYR+LLE EDCKLP PC+ Sbjct: 362 MQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCS 421 Query: 411 TACKPVIRVPSVPPVPCVPSVPCTPAPQVG 440 T+ PS PC P C P G Sbjct: 422 TS-------PSCVTAPCAPRPSCGPCTTCG 444 >gi|55770882 keratin 37 [Homo sapiens] Length = 449 Score = 449 bits (1155), Expect = e-126 Identities = 237/410 (57%), Positives = 299/410 (72%), Gaps = 13/410 (3%) Query: 24 GISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGS---CLPGSY-----LSSECHTS 75 G V+ + C + ++A A + R G + LG CLP + L CH Sbjct: 31 GCQPVAEANAASMCLLANVAHA----NRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIP 86 Query: 76 GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPY 135 G +G G + + + NG EKETM+FLNDRLANYLEKVRQLE+ENAELE+ + E + Sbjct: 87 GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHEST 146 Query: 136 ICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEAD 195 +CPDYQSYF+TIE+ QQKIL +K+ENARL++QIDNAKLAADDFR K E+E SL QLVEAD Sbjct: 147 VCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEAD 206 Query: 196 INGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPP 255 G +++LD+ TL KADLEAQ ESLKEE + LK NHE+EV +LR QLG++ +E+D P Sbjct: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPT 266 Query: 256 VDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRT 315 +DLN++L +MR QYEA+VE N +DVE WF Q+E ++ Q +S SE+LQCCQ+EI+ELR T Sbjct: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCT 326 Query: 316 VNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQE 375 VNALE+E QAQH++++ L+++L E E RY ++LAQMQ LISN+E QLSEIR DLERQNQE Sbjct: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQE 386 Query: 376 YQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPV 425 YQVLLDVKARLE EIATYR+LLE EDCKLP PC+T PS PV Sbjct: 387 YQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPAS-CTSCPSCGPV 435 >gi|15431310 keratin 14 [Homo sapiens] Length = 472 Score = 444 bits (1143), Expect = e-125 Identities = 256/482 (53%), Positives = 324/482 (67%), Gaps = 41/482 (8%) Query: 5 TCTPTF-STGSIKGLCGTAGGI----SRVSSIRSVGSCRVPSLAGAAGYISSAR---SGL 56 TC+ F S+ S+KG CG GGI SR+SS+ + GSCR PS G +SS+R G Sbjct: 3 TCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGA 62 Query: 57 SGLGSCLPGSYLSSECHT-SGFVGS-------------GGWFC--EGSFNGSEKETMQFL 100 GLG G + SS SGF G GG F +G GSEK TMQ L Sbjct: 63 YGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQNL 122 Query: 101 NDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSE 160 NDRLA+YL+KVR LE NA+LE +I++WY+ Q P DY YFKTIED + KIL + Sbjct: 123 NDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVD 182 Query: 161 NARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESL 220 NA ++LQIDNA+LAADDFRTKYETEL+LR VEADINGLRR+LDELTL +ADLE Q+ESL Sbjct: 183 NANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESL 242 Query: 221 KEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDV 280 KEEL LKKNHEEE++ LR Q+G +NVE+DAAP VDL++IL +MR QYE + E NR+D Sbjct: 243 KEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDA 302 Query: 281 EAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAET 340 E WF T+TEELN++V ++SE +Q ++EI ELRRT+ LEIELQ+Q SM+ SLE++L ET Sbjct: 303 EEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEET 362 Query: 341 EARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE 400 + RY QLAQ+Q +I +VE QL+++RC++E+QNQEY++LLDVK RLE EIATYR LLEGE Sbjct: 363 KGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE 422 Query: 401 DCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSRE 460 D L ++ + V S QIRT ++ DGKV+S+ E Sbjct: 423 DAHLSSSQFSSGSQSSRDVTS-----------------SSRQIRTKVMDVHDGKVVSTHE 465 Query: 461 HV 462 V Sbjct: 466 QV 467 >gi|4557701 keratin 17 [Homo sapiens] Length = 432 Score = 432 bits (1112), Expect = e-121 Identities = 247/458 (53%), Positives = 308/458 (67%), Gaps = 46/458 (10%) Query: 11 STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSS 70 S+ SIKG G GG SR S CR L+G G S GLGS L GS SS Sbjct: 10 SSSSIKGSSGLGGGSSRTS-------CR---LSGGLGAGSCRLGSAGGLGSTLGGSSYSS 59 Query: 71 ECHTSGFVGSGGWF------CEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESR 124 C++ GSGG + +G G EK TMQ LNDRLA+YL+KVR LE N ELE + Sbjct: 60 -CYS---FGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVK 115 Query: 125 IQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYET 184 I++WY+ Q P DY Y++TIE+ Q KIL +NA ++LQIDNA+LAADDFRTK+ET Sbjct: 116 IRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFET 175 Query: 185 ELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGD 244 E +LR VEADINGLRR+LDELTL +ADLE Q+E+LKEEL LKKNHEEE++ LR Q+G Sbjct: 176 EQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGG 235 Query: 245 RLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQC 304 +NVE+DAAP VDL++IL +MR QYE + E NR+D E WF ++TEELN++V ++SE +Q Sbjct: 236 EINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQS 295 Query: 305 CQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSE 364 ++EI ELRRT+ ALEIELQ+Q SM+ SLE LAETE RY QL+Q+Q LI +VE QL++ Sbjct: 296 GKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQ 355 Query: 365 IRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPP 424 +RC++E+QNQEY++LLDVK RLE EIATYR LLEGED L Sbjct: 356 LRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL-------------------- 395 Query: 425 VPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHV 462 P Q+RTI EE++DGKVISSRE V Sbjct: 396 ------TQYKKEPVTTRQVRTIVEEVQDGKVISSREQV 427 >gi|24430192 keratin 16 [Homo sapiens] Length = 473 Score = 432 bits (1112), Expect = e-121 Identities = 239/429 (55%), Positives = 299/429 (69%), Gaps = 26/429 (6%) Query: 5 TCTPTF-STGSIKGLCGTAGGI----SRVSSIRSVGSCRVPSLAGAAGYISSARS--GLS 57 TC+ F S+ S+KG CG GGI SR+SS+ + GSCR PS G +SS S G Sbjct: 3 TCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGAC 62 Query: 58 GLGSCLPGSYLSSECHTSGF-----------------VGSGGWFC--EGSFNGSEKETMQ 98 GLG G + SS SGF G GG F +G GSEK TMQ Sbjct: 63 GLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQ 122 Query: 99 FLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTK 158 LNDRLA+YL+KVR LE NA+LE +I++WY+ Q P DY YFKTIED + KI+ Sbjct: 123 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAAT 182 Query: 159 SENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVE 218 ENA+ +LQIDNA+LAADDFRTKYE EL+LRQ VEAD+NGLRR+LDELTL + DLE Q+E Sbjct: 183 IENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIE 242 Query: 219 SLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRR 278 LKEEL L+KNHEEE+ LR Q G +NVE+DAAP VDL++IL +MR QYE + E NRR Sbjct: 243 GLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRR 302 Query: 279 DVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLA 338 D E WF ++TEELN++V S+SE +Q ++E+ ELRR + LEIELQ+Q SM+ SLE++L Sbjct: 303 DAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLE 362 Query: 339 ETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLE 398 ET+ RY QL+Q+Q LI +VE QL+++RC++E+Q+QEYQ+LLDVK RLE EIATYR LLE Sbjct: 363 ETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLE 422 Query: 399 GEDCKLPPQ 407 GED L Q Sbjct: 423 GEDAHLSSQ 431 >gi|24430190 keratin 15 [Homo sapiens] Length = 456 Score = 400 bits (1029), Expect = e-111 Identities = 225/413 (54%), Positives = 285/413 (69%), Gaps = 14/413 (3%) Query: 4 QTCTPTFSTGSIKGLCGTAGG-------ISRVSSIRSVG--SCRVPSLAGAAGYISSAR- 53 QT + TF GS +G AGG +S RS+ S R S GY R Sbjct: 7 QTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRV 66 Query: 54 SGLSG-LGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVR 112 G G GS G + GF G G G +G+EK TMQ LNDRLA+YL+KVR Sbjct: 67 CGFGGGAGSVFGGGFGGGV--GGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVR 124 Query: 113 QLERENAELESRIQEWYEFQIPYICP-DYQSYFKTIEDFQQKILLTKSENARLVLQIDNA 171 LE NA+LE +I +WY+ Q P DY YFKTIE+ + KI+ T +N+R++L+IDNA Sbjct: 125 ALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNA 184 Query: 172 KLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNH 231 +LAADDFR KYE EL+LRQ VEADINGLRR+LDELTL + DLE Q+E L EEL LKKNH Sbjct: 185 RLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNH 244 Query: 232 EEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEEL 291 EEE+ QL ++NVE+DAAP VDL ++L +MR QYEA+ E NRRDVEAWF ++TEEL Sbjct: 245 EEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEEL 304 Query: 292 NQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQM 351 N++V S++E +Q +TEI +LRRT+ LEIELQ+Q SM+ LE++LAETE RY++QL Q+ Sbjct: 305 NKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQI 364 Query: 352 QCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKL 404 Q LI +EAQLSE+RC++E QNQEY++LLD+K RLE EIATYR LLEG+D K+ Sbjct: 365 QGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417 >gi|24234699 keratin 19 [Homo sapiens] Length = 400 Score = 395 bits (1015), Expect = e-110 Identities = 211/379 (55%), Positives = 267/379 (70%), Gaps = 3/379 (0%) Query: 26 SRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFC 85 S SS +G V G A S G G G + + S + + G G Sbjct: 10 SATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVL 69 Query: 86 ---EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQS 142 +G G+EK TMQ LNDRLA+YL+KVR LE N ELE +I++WY+ Q P DY Sbjct: 70 TASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSH 129 Query: 143 YFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRI 202 Y+ TI+D + KIL EN+R+VLQIDNA+LAADDFRTK+ETE +LR VEADINGLRR+ Sbjct: 130 YYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRV 189 Query: 203 LDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKIL 262 LDELTL + DLE Q+E LKEEL LKKNHEEE+S LR Q+G +++VEVD+AP DL KIL Sbjct: 190 LDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKIL 249 Query: 263 EDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIE 322 DMR QYE + E NR+D EAWF ++TEELN++V +EQLQ ++E+ +LRRT+ LEIE Sbjct: 250 SDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIE 309 Query: 323 LQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDV 382 LQ+Q SM+ +LE TLAETEAR+ +QLA +Q LIS +EAQL ++R D ERQNQEYQ L+D+ Sbjct: 310 LQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDI 369 Query: 383 KARLEGEIATYRHLLEGED 401 K+RLE EIATYR LLEG++ Sbjct: 370 KSRLEQEIATYRSLLEGQE 388 >gi|131412225 keratin 13 isoform a [Homo sapiens] Length = 458 Score = 377 bits (968), Expect = e-104 Identities = 214/406 (52%), Positives = 275/406 (67%), Gaps = 26/406 (6%) Query: 5 TCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAA---GYISSARSGLSG-LG 60 TC+ F +G G G GG+S C AG+ GY G G LG Sbjct: 31 TCSTRFVSGGSAG--GYGGGVS----------CGFGGGAGSGFGGGYGGGLGGGYGGGLG 78 Query: 61 SCLPGSYLSSECHTSGFVGSGGWFCEGSF-NGSEKETMQFLNDRLANYLEKVRQLERENA 119 G + GFV G C+G G+EK TMQ LNDRLA+YLEKVR LE NA Sbjct: 79 GGFGGGF------AGGFVDFGA--CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130 Query: 120 ELESRIQEWYEFQIPYICP-DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDF 178 +LE +I++W+ Q P DY Y+KTIE+ + KIL EN R++L+IDNA+LAADDF Sbjct: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190 Query: 179 RTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVL 238 R KYE EL+LRQ VEADINGLRR+LDELTL K DLE Q+ESL EEL +KKNHEEE+ Sbjct: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250 Query: 239 RCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSS 298 Q+ ++NVE+DA P +DL ++L +MR QYEA+ E NRRD E WF+ ++ ELN++V ++ Sbjct: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310 Query: 299 SEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNV 358 + +Q +TEI ELRRT+ LEIELQ+Q SM+ LE+T+AETE RY+ QL Q+Q LIS++ Sbjct: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370 Query: 359 EAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKL 404 EAQLSE+R ++E QNQEY++LLD+K RLE EIATYR LLEG+D K+ Sbjct: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 416 >gi|131412228 keratin 13 isoform b [Homo sapiens] Length = 420 Score = 377 bits (967), Expect = e-104 Identities = 215/410 (52%), Positives = 275/410 (67%), Gaps = 26/410 (6%) Query: 5 TCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAA---GYISSARSGLSG-LG 60 TC+ F +G G G GG+S C AG+ GY G G LG Sbjct: 31 TCSTRFVSGGSAG--GYGGGVS----------CGFGGGAGSGFGGGYGGGLGGGYGGGLG 78 Query: 61 SCLPGSYLSSECHTSGFVGSGGWFCEGSF-NGSEKETMQFLNDRLANYLEKVRQLERENA 119 G + GFV G C+G G+EK TMQ LNDRLA+YLEKVR LE NA Sbjct: 79 GGFGGGF------AGGFVDFGA--CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130 Query: 120 ELESRIQEWYEFQIPYICP-DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDF 178 +LE +I++W+ Q P DY Y+KTIE+ + KIL EN R++L+IDNA+LAADDF Sbjct: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190 Query: 179 RTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVL 238 R KYE EL+LRQ VEADINGLRR+LDELTL K DLE Q+ESL EEL +KKNHEEE+ Sbjct: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250 Query: 239 RCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSS 298 Q+ ++NVE+DA P +DL ++L +MR QYEA+ E NRRD E WF+ ++ ELN++V ++ Sbjct: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310 Query: 299 SEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNV 358 + +Q +TEI ELRRT+ LEIELQ+Q SM+ LE+T+AETE RY+ QL Q+Q LIS++ Sbjct: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370 Query: 359 EAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQP 408 EAQLSE+R ++E QNQEY++LLD+K RLE EIATYR LLEG+D K P Sbjct: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKKRQPP 420 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 359 bits (922), Expect = 3e-99 Identities = 212/399 (53%), Positives = 266/399 (66%), Gaps = 21/399 (5%) Query: 11 STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSS 70 S+G GL G GG R GS S G+ G S G G GS GS+ Sbjct: 70 SSGGYGGLGGFGGGSFR-------GSYGSSSFGGSYG--GSFGGGSFGGGSFGGGSFGGG 120 Query: 71 ECHTSGFVGS--GGWFCEGSF-NGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQE 127 GF G GG+ +G +G+EK TMQ LNDRLA+YL+KVR LE N ELE +I+E Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKE 180 Query: 128 WYEFQ------IPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTK 181 WYE P DY Y+KTI+D + +IL ++NA ++LQIDNA+LAADDFR K Sbjct: 181 WYEKHGNSHQGEPR---DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLK 237 Query: 182 YETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQ 241 YE E++LRQ VEADINGLRR+LDELTL KADLE Q+ESL EEL LKKNHEEE+ LR Sbjct: 238 YENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNV 297 Query: 242 LGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQ 301 +NVE++AAP VDL ++L +MR QYE L E NR+D EAWFN +++EL ++ ++ EQ Sbjct: 298 STGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQ 357 Query: 302 LQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQ 361 + ++EI ELRR V ALEIELQ+Q +++ SLE++LAETE RY QL+Q+Q IS +E Q Sbjct: 358 ISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQ 417 Query: 362 LSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE 400 L +IR + E QN EYQ LLD+K RLE EI TYR LLEGE Sbjct: 418 LQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456 >gi|4557699 keratin 12 [Homo sapiens] Length = 494 Score = 350 bits (898), Expect = 2e-96 Identities = 215/460 (46%), Positives = 284/460 (61%), Gaps = 30/460 (6%) Query: 13 GSIKGLCGTAGG----ISRVSSIRSVGSCRVPSLAGA--AGYISSARSG-LSGLGSCLPG 65 GS G + GG S S G S+AG AGY + G GLG G Sbjct: 44 GSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGG 103 Query: 66 SYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRI 125 S G +G G +GSEKETMQ LNDRLA+YL+KVR LE N ELE++I Sbjct: 104 S------PGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKI 157 Query: 126 QEWYEFQIPYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTK 181 +EWYE + DY Y+ IED + KI+ NA+L+LQIDNA+LAA+DFR K Sbjct: 158 REWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMK 217 Query: 182 YETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQ 241 YE EL+LRQ VEADINGLRR+LDELTL + DLE Q+ESL EEL +KKNHE+E+ R Sbjct: 218 YENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVG 277 Query: 242 LGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQ 301 ++VE+DAAP VDL ++L DMR QYE + E NR+D EAWF ++ EL +++ +++EQ Sbjct: 278 GPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQ 337 Query: 302 LQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQ 361 LQ ++E+ +LRR LEIELQ+Q +M+ SLE +LAE E Y +QL+Q+Q LISN+EAQ Sbjct: 338 LQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQ 397 Query: 362 LSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE--DCKLPPQPCATACKPVIRV 419 L ++R D ERQN ++Q LL+VKARLE EI TYR LL+GE L T K + Sbjct: 398 LLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQ- 456 Query: 420 PSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSR 459 S + P +I+T+ +E+ +G+V+SS+ Sbjct: 457 ----------STDSSKDPTKTRKIKTVVQEMVNGEVVSSQ 486 >gi|114431246 keratin 25D [Homo sapiens] Length = 464 Score = 343 bits (881), Expect = 1e-94 Identities = 209/456 (45%), Positives = 275/456 (60%), Gaps = 40/456 (8%) Query: 26 SRVSSIRSVGSCRVPSLAGAAGYISSARSGLS------------GLGSCLPGSYLSSECH 73 SR +RS G+ V L G AG+ S+ G S GLGS GS+ Sbjct: 9 SRHVCLRS-GAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALG 67 Query: 74 TS---GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYE 130 + GF GS G G +G+EK TMQ LNDRLA+YL+ VR LE NAELE +I+ WYE Sbjct: 68 NAACIGFAGSEG----GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYE 123 Query: 131 FQIPYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETEL 186 P C DY Y TIED + KI+ + + NA ++LQIDNA+LAADDFR KYE EL Sbjct: 124 KYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENEL 183 Query: 187 SLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRL 246 +L Q VEADINGLRR+LDELTLC+ D E Q ESL EE+ LKKNHEEE+ L+C G + Sbjct: 184 TLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNV 243 Query: 247 NVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQ 306 NVE++AAP VDL +L +MR +YEAL E NR+D EAWFN ++ L QQ+ S + Sbjct: 244 NVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFAR 303 Query: 307 TEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIR 366 +++ E+RRT+ LEI+LQ+ + ++SLE +L ETE+ Y +QLAQ+Q I +E QL ++R Sbjct: 304 SQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVR 363 Query: 367 CDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVP 426 + E Q EY+ LLDVK LE EI TY L++G+ +C S P Sbjct: 364 TETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD---------GNSCSKSKGFGSGSPGN 414 Query: 427 CVPSVPCTPAPQVGTQIRTITEEI-RDGKVISSREH 461 + T T ++T+ EE+ + GKV+SSR H Sbjct: 415 SSKDLSKT------TLVKTVVEELDQRGKVLSSRIH 444 >gi|27894337 keratin 20 [Homo sapiens] Length = 424 Score = 342 bits (877), Expect = 4e-94 Identities = 200/439 (45%), Positives = 273/439 (62%), Gaps = 33/439 (7%) Query: 26 SRVSSIRSVGSCRVPSLAGAAGY--ISSARSGLSGLGSCLPGSYLSSECHT----SGFVG 79 SR S RS+ S + G + + S G G G +S+ HT S G Sbjct: 4 SRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGG--RGIRISNSRHTVNYGSDLTG 61 Query: 80 SGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPD 139 G F G+EK MQ LNDRLA+YLEKVR LE+ N++LE +I++WYE P D Sbjct: 62 GGDLFV-----GNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRD 116 Query: 140 YQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGL 199 Y +Y++ IE+ + +I + +NAR VLQIDNAKLAA+DFR KYETE +R VEAD+ GL Sbjct: 117 YSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGL 176 Query: 200 RRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLN 259 ++ D+LTL K DLE Q+E L ++L LKK H+EEV L LG+ +NVEVDAAP ++L Sbjct: 177 NKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLG 236 Query: 260 KILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNAL 319 I+ +MR +YE + + N ++ + F QT L QQV ++E+L+ + ++ ELRRT +L Sbjct: 237 VIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSL 296 Query: 320 EIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVL 379 EIELQ+ SM+ SLE TL ET+ARYSSQLA +Q L+S++EAQL +IR ++ERQN EY +L Sbjct: 297 EIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHIL 356 Query: 380 LDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQV 439 LD+K RLE EIATYR LLEGED K +T + I+ Sbjct: 357 LDIKTRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKT------------------- 397 Query: 440 GTQIRTITEEIRDGKVISS 458 +I+T+ +E+ DGKV+SS Sbjct: 398 -RKIKTVVQEVVDGKVVSS 415 >gi|153945736 keratin 27 [Homo sapiens] Length = 459 Score = 340 bits (871), Expect = 2e-93 Identities = 189/389 (48%), Positives = 251/389 (64%), Gaps = 17/389 (4%) Query: 27 RVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGS---CLPGSYLSSECHTSGFVGSGGW 83 R+ S GS R+ S G AG+ + G+ G+GS C G S+ + G +G G Sbjct: 11 RLGSCGGTGSVRLSS--GGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGG-LGGGSA 67 Query: 84 FC-------EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYI 136 C G +G+EK TMQ LNDRLA+YLE VR LE NA+LE +I+ WYE P Sbjct: 68 SCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGS 127 Query: 137 CP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLV 192 C DY YF I++ + +I+ + NA +VLQ DNA+L ADDFR K+E EL+L Q V Sbjct: 128 CRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSV 187 Query: 193 EADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDA 252 EADINGLRR+LDELTLC+ DLE Q+E+L EEL LKKNHEEE+ L+C G +NVE++A Sbjct: 188 EADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNA 247 Query: 253 APPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIEL 312 AP VDL +L +MR +YEAL E NRRD EAWFN ++ L QQ+ + + E+IE+ Sbjct: 248 APGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEM 307 Query: 313 RRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQ 372 +RT+ LEIELQ+ + ++SLE +L ETE+ Y +QLAQ+Q I +E QL ++R + E Q Sbjct: 308 KRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQ 367 Query: 373 NQEYQVLLDVKARLEGEIATYRHLLEGED 401 EY+ LLD+K LE EI TY L++GED Sbjct: 368 KLEYEQLLDIKVHLEKEIETYCLLIDGED 396 >gi|192807292 keratin 24 [Homo sapiens] Length = 525 Score = 331 bits (848), Expect = 1e-90 Identities = 206/463 (44%), Positives = 274/463 (59%), Gaps = 24/463 (5%) Query: 11 STGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSS 70 S G G C GG S G S G +G+ G GS GS S Sbjct: 63 SFGGGFGSCSVGGGFGGASG-SGTGFGGGSSFGGVSGF---------GRGSGFCGSSRFS 112 Query: 71 ECHTSGFV----GSGGWFCEGS-FNGSEKETMQFLNDRLANYLEKVRQLERENAELESRI 125 T GF G GG +G F+G EK+TMQ LNDRLANYL+KVR LE N +LE++I Sbjct: 113 SGATGGFYSYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKI 172 Query: 126 QEWYEFQIPYICP-----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRT 180 +EWY+ P DY Y+ IED + +I+ ENA ++L IDNA+LAADDFR Sbjct: 173 KEWYDKYGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRL 232 Query: 181 KYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRC 240 KYE EL LRQ VEADINGLR++LD+LT+ ++DLE Q+ES EEL L+KNHEEE+ ++ Sbjct: 233 KYENELCLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQG 292 Query: 241 QLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSE 300 G + VE++AAP DL K+L DMR QYE L E NRR+ E FN Q+ L Q+ + + Sbjct: 293 SSGGEVTVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAG 352 Query: 301 QLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEA 360 + EI EL+RT+ ALEIELQ+Q +M++SLE TLA+TEA Y +QL+++Q IS +E Sbjct: 353 AATSAKNEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEE 412 Query: 361 QLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVP 420 ++ +I + + QN EY+ LLD+K RLE EI TYR LL+GE + + Sbjct: 413 EICQIWGETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMG 472 Query: 421 SVPPVP-CVPSVPCTPAPQVGTQIR---TITEEIRDGKVISSR 459 S V S C+ + ++ R TI EE+ DGKV+SS+ Sbjct: 473 SRDLVSGDSRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQ 515 >gi|31559829 keratin 25 [Homo sapiens] Length = 450 Score = 328 bits (841), Expect = 6e-90 Identities = 182/384 (47%), Positives = 245/384 (63%), Gaps = 18/384 (4%) Query: 33 SVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFC------- 85 + GS R+ G + + G+SG+GS ++ S +SG GG C Sbjct: 17 TTGSLRL--YGGGTSFGTGNSCGISGIGSGFSSAFGGS---SSGGNTGGGNPCAGFTVNE 71 Query: 86 EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP----DYQ 141 G +G+EK TMQ LNDRLA+YL+ V LE NA+LE +I+ WYE P C DY Sbjct: 72 RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYS 131 Query: 142 SYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRR 201 YF I+D + +I+ + + NA VLQIDNA+L ADDFR KYE EL+L Q VEAD+NGLRR Sbjct: 132 RYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRR 191 Query: 202 ILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKI 261 +LDE+TLC+ DLE Q E+L EE+ LKKNH+EE+ VL+C G +NVE++AAP VDL + Sbjct: 192 VLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVL 251 Query: 262 LEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEI 321 L +MR +YEAL E NRRD EAWFN ++ L QQ+ + E+ E++RT+ LEI Sbjct: 252 LNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEI 311 Query: 322 ELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLD 381 ELQ+ + ++SLE +L ETE+ Y +QLAQ+Q I +E QL ++R + E Q EY+ LLD Sbjct: 312 ELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLD 371 Query: 382 VKARLEGEIATYRHLLEGED--CK 403 +K LE EI TY L+ G+D CK Sbjct: 372 IKLHLEKEIETYCLLIGGDDGACK 395 >gi|40354195 keratin 18 [Homo sapiens] Length = 430 Score = 313 bits (801), Expect = 3e-85 Identities = 181/388 (46%), Positives = 258/388 (66%), Gaps = 18/388 (4%) Query: 29 SSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTS--GFVGSGGWFCE 86 ++ RS+GS + PS A +SSA S +G G GS +S TS G +GSGG Sbjct: 11 TNYRSLGSVQAPSYG--ARPVSSAASVYAGAGGS--GSRISVSRSTSFRGGMGSGG-LAT 65 Query: 87 GSFNG--------SEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP 138 G G +EKETMQ LNDRLA+YL++VR LE EN LES+I+E E + P + Sbjct: 66 GIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-R 124 Query: 139 DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADING 198 D+ YFK IED + +I +NAR+VLQIDNA+LAADDFR KYETEL++RQ VE DI+G Sbjct: 125 DWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHG 184 Query: 199 LRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDR-LNVEVDAAPPVD 257 LR+++D+ + + LE ++E+LKEEL+ +KKNHEEEV L+ Q+ L VEVDA D Sbjct: 185 LRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQD 244 Query: 258 LNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVN 317 L KI+ D+R QY+ L NR +++ +++ Q EE V + S ++ +T + ELRRTV Sbjct: 245 LAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQ 304 Query: 318 ALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQ 377 +LEI+L + +++ SLE++L E EARY+ Q+ Q+ ++ ++E++L++ R + +RQ QEY+ Sbjct: 305 SLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYE 364 Query: 378 VLLDVKARLEGEIATYRHLLE-GEDCKL 404 LL++K +LE EIATYR LLE GED L Sbjct: 365 ALLNIKVKLEAEIATYRRLLEDGEDFNL 392 >gi|4557888 keratin 18 [Homo sapiens] Length = 430 Score = 313 bits (801), Expect = 3e-85 Identities = 181/388 (46%), Positives = 258/388 (66%), Gaps = 18/388 (4%) Query: 29 SSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTS--GFVGSGGWFCE 86 ++ RS+GS + PS A +SSA S +G G GS +S TS G +GSGG Sbjct: 11 TNYRSLGSVQAPSYG--ARPVSSAASVYAGAGGS--GSRISVSRSTSFRGGMGSGG-LAT 65 Query: 87 GSFNG--------SEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP 138 G G +EKETMQ LNDRLA+YL++VR LE EN LES+I+E E + P + Sbjct: 66 GIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-R 124 Query: 139 DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADING 198 D+ YFK IED + +I +NAR+VLQIDNA+LAADDFR KYETEL++RQ VE DI+G Sbjct: 125 DWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHG 184 Query: 199 LRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDR-LNVEVDAAPPVD 257 LR+++D+ + + LE ++E+LKEEL+ +KKNHEEEV L+ Q+ L VEVDA D Sbjct: 185 LRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQD 244 Query: 258 LNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVN 317 L KI+ D+R QY+ L NR +++ +++ Q EE V + S ++ +T + ELRRTV Sbjct: 245 LAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQ 304 Query: 318 ALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQ 377 +LEI+L + +++ SLE++L E EARY+ Q+ Q+ ++ ++E++L++ R + +RQ QEY+ Sbjct: 305 SLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYE 364 Query: 378 VLLDVKARLEGEIATYRHLLE-GEDCKL 404 LL++K +LE EIATYR LLE GED L Sbjct: 365 ALLNIKVKLEAEIATYRRLLEDGEDFNL 392 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 303 bits (775), Expect = 3e-82 Identities = 175/385 (45%), Positives = 240/385 (62%), Gaps = 5/385 (1%) Query: 20 GTAGGISRVSSIRSVGS-CRVPSLAGAAGYISSARSGLS---GLGSCLPGSYLSSECHTS 75 G+ GG S S G R A GY SS G G G G Y S Sbjct: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFG 135 Query: 76 GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPY 135 GF G G G +EK TMQ LN RLA+YL+KV+ LE N +LE++IQ+WY+ + P Sbjct: 136 GFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPA 195 Query: 136 -ICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEA 194 I +Y Y+ TI+D + +I+ N + +L IDN ++ DDFR K+E E +LRQ V+A Sbjct: 196 AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDA 255 Query: 195 DINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAP 254 DINGLR++LD LT+ K+DLE Q E+L+EELM LKKNH+EE+S L Q +NVE++ AP Sbjct: 256 DINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAP 315 Query: 255 PVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRR 314 DL K L DMR +YE L+ NR+D+E + TQ ++ +V SS +++Q E+ +LR Sbjct: 316 GKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRH 375 Query: 315 TVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQ 374 V LEIELQ+Q S + +LE +L +T+ RY QL +Q ISN+EAQ++++R ++E QNQ Sbjct: 376 GVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQ 435 Query: 375 EYQVLLDVKARLEGEIATYRHLLEG 399 EY +LL +K RLE EI TY +LLEG Sbjct: 436 EYSLLLSIKMRLEKEIETYHNLLEG 460 >gi|31559815 keratin 26 [Homo sapiens] Length = 468 Score = 298 bits (763), Expect = 7e-81 Identities = 179/394 (45%), Positives = 233/394 (59%), Gaps = 14/394 (3%) Query: 22 AGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPG-SYLSSECHTSGFVGS 80 +GG R+ S G AG + S L G S S C++ G +GS Sbjct: 6 SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGS 65 Query: 81 GGWFCEGSF-------NGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQI 133 G C G +G+EK TMQ LNDRLA+YL+ V LE NA+LE +I+ YE Sbjct: 66 GA--CAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCE 123 Query: 134 PYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLR 189 P DY YF IED +++I NA +VLQ DNA+L ADDFR KYE EL+L Sbjct: 124 PGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALH 183 Query: 190 QLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVE 249 VEAD +GLRR+LDELTLC DLE Q E+L EEL LKK+HEEE+ VL+ G +NVE Sbjct: 184 HSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVE 243 Query: 250 VDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEI 309 ++A P VDL +L +MR +YE L E NR+D EAWFN ++ L QQ+ + E+ Sbjct: 244 MNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNEL 303 Query: 310 IELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDL 369 EL+R + LEIELQ+ ++++S E +LAETE Y +QL Q+Q I +E QL +IR + Sbjct: 304 TELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTET 363 Query: 370 ERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCK 403 E Q EY+ LLDVK LE EI Y +LL+GE+ K Sbjct: 364 EGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397 >gi|27894339 keratin 23 [Homo sapiens] Length = 422 Score = 289 bits (739), Expect = 4e-78 Identities = 166/395 (42%), Positives = 240/395 (60%), Gaps = 25/395 (6%) Query: 9 TFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYL 68 +FS G GG R S R P++ G AG G+ + S+ Sbjct: 6 SFSQTPSASFHGAGGGWGRPRSFP-----RAPTVHGGAG------------GARISLSFT 48 Query: 69 SSECHTSGFVGSGGWFCEGS---FNGSEKETMQFLNDRLANYLEKVRQLERENAELESRI 125 + C G G W S G+ K TMQ LNDRLA+YLEKVR LE N +LESRI Sbjct: 49 TRSCPPPG----GSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRI 104 Query: 126 QEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETE 185 +W++ + P DY Y + I Q++I+ K NA+++L IDNA++A DDF KYE E Sbjct: 105 LKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENE 164 Query: 186 LSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDR 245 S ++ +E ++ GLRR LD LT+ DLE +VE +++EL+ +KK+HE+E+ Sbjct: 165 HSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFN 224 Query: 246 LNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCC 305 +NV+VD P DL K+LEDMR +YE +++ RD++ W+ Q+ ++Q+ S + +Q Sbjct: 225 VNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSR 283 Query: 306 QTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEI 365 Q +I EL+RT ALEI+LQ Q+S +++LE+ L+ET++RYS +L MQ +IS+ E +L+++ Sbjct: 284 QGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQL 343 Query: 366 RCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE 400 R +LERQN EYQVLL +K LE EI TYR LLEGE Sbjct: 344 RHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGE 378 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.131 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,984,178 Number of Sequences: 37866 Number of extensions: 778838 Number of successful extensions: 6919 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 158 Number of HSP's successfully gapped in prelim test: 426 Number of HSP's that attempted gapping in prelim test: 5199 Number of HSP's gapped (non-prelim): 1558 length of query: 467 length of database: 18,247,518 effective HSP length: 106 effective length of query: 361 effective length of database: 14,233,722 effective search space: 5138373642 effective search space used: 5138373642 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.