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Search of human proteins with 4504619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 589 e-169
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 225 3e-59
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 173 2e-43
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 105 4e-23
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 90 3e-18
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 84 2e-16
gi|144226847 obscurin-like 1 [Homo sapiens] 57 2e-08
gi|222352127 sidekick 2 [Homo sapiens] 54 2e-07
gi|54873613 agrin [Homo sapiens] 54 2e-07
gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken) ... 54 2e-07
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 52 4e-07
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 52 6e-07
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 52 8e-07
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 52 8e-07
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 52 8e-07
gi|119220552 sidekick 1 [Homo sapiens] 49 4e-06
gi|193083136 leucine-rich repeat, immunoglobulin-like and transm... 49 5e-06
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 49 6e-06
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 49 6e-06
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 49 6e-06
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 49 6e-06
gi|153792294 myopalladin [Homo sapiens] 49 6e-06
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 48 8e-06
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 48 8e-06
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 48 8e-06
gi|109150416 peroxidasin [Homo sapiens] 48 1e-05
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 48 1e-05
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 47 1e-05
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur... 47 1e-05
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur... 47 1e-05
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 589 bits (1519), Expect = e-169
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC 60
MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC
Sbjct: 1 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC 60
Query: 61 PMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVC 120
PMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVC
Sbjct: 61 PMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVC 120
Query: 121 GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS 180
GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS
Sbjct: 121 GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS 180
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK
Sbjct: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
Query: 241 EDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 282
EDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL
Sbjct: 241 EDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 282
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 225 bits (574), Expect = 3e-59
Identities = 115/263 (43%), Positives = 141/263 (53%), Gaps = 22/263 (8%)
Query: 16 LLLLLLPLSSSSSSDT-----------CGPCEPASCPPLPPLGCLLGETRDACGCCPMCA 64
LLLLLLPL S CGPC P CP P D CGCC C
Sbjct: 11 LLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDECGCCARCL 70
Query: 65 RGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDG 124
EG CGG GR C PG+ C AA P +G+CVC R VCGSDG
Sbjct: 71 GAEGASCGGRAGGR--CGPGLVCASQ---------AAGAAPEGTGLCVCAQRGTVCGSDG 119
Query: 125 TTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVI 184
+YPS C LR ++ + + G CE P +V PP+ + NVTGAQV LSCEV
Sbjct: 120 RSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVR 179
Query: 185 GIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAG 244
+PTPV+ W KV + G Q E LPGD N+A+Q RGGP HE T W+L++PL KED G
Sbjct: 180 AVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEG 239
Query: 245 EYECHASNSQGQASASAKITVVD 267
Y+CHA+N G+A + + +TV+D
Sbjct: 240 VYQCHAANMVGEAESHSTVTVLD 262
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 173 bits (438), Expect = 2e-43
Identities = 93/242 (38%), Positives = 124/242 (51%), Gaps = 20/242 (8%)
Query: 27 SSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGR--GYCAPG 84
+ + C PC P C P GCL G RDACGCC CA EG+ C + G+C
Sbjct: 48 AEGEGCAPCRPEECAA--PRGCLAGRVRDACGCCWECANLEGQLCDLDPSAHFYGHCGEQ 105
Query: 85 MECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRG 144
+EC R G + G +C C+S+ P+CGSDG TY C+L+ A A +R
Sbjct: 106 LEC------RLDTGGDLSRGEVPEPLCACRSQSPLCGSDGHTYSQICRLQEA---ARARP 156
Query: 145 EKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQ 204
+ +T G CE GP IV+ P D WNVTG V CEV P + W K +Q
Sbjct: 157 DANLTVAHPGPCESGPQIVSHPYDTWNVTGQDVIFGCEVFAYPMASIEWRK---DGLDIQ 213
Query: 205 RTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKIT 264
LPGD ++++Q RGGP++ EVTGW+ + + D G Y C N+ GQ A A +T
Sbjct: 214 ----LPGDDPHISVQFRGGPQRFEVTGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLT 269
Query: 265 VV 266
V+
Sbjct: 270 VL 271
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 105 bits (262), Expect = 4e-23
Identities = 64/162 (39%), Positives = 79/162 (48%), Gaps = 32/162 (19%)
Query: 16 LLLLLLPLSSSSSSDTCGP-----------CEPASCPPLPPLGCLLGETRDACGCCPMCA 64
LLLLLL +S+ G CEPA CPP P C G RDACGCC +C
Sbjct: 11 LLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPE-HCEGGRARDACGCCEVCG 69
Query: 65 RGEGEPCGGGGAGRGYCAPGMECV-------KSRKRRKGKAGAAAGGPGVSGVCVCKSRY 117
EG C G G C G++CV + RR+ +A G+CVC S
Sbjct: 70 APEGAAC---GLQEGPCGEGLQCVVPFGVPASATVRRRAQA----------GLCVCASSE 116
Query: 118 PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQG 159
PVCGSD TY + CQLRAAS+R+E + + +G C QG
Sbjct: 117 PVCGSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQG 158
>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
Length = 476
Score = 89.7 bits (221), Expect = 3e-18
Identities = 72/212 (33%), Positives = 94/212 (44%), Gaps = 32/212 (15%)
Query: 1 MERPSLRALLLGAA---GLLLLLLPL-----SSSSSSDTC-GPCEPASCPPLPPLGCLLG 51
M RP LR LG GLLLLL+P+ + +C C+P CP LP C LG
Sbjct: 1 MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPT--CALG 58
Query: 52 ETR--DACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSG 109
T D C CC +C E E C GGA CAPG++C++ + PG
Sbjct: 59 TTPVFDLCRCCRVCPAAEREVC--GGAQGQPCAPGLQCLQPLR------------PGFPS 104
Query: 110 VCVCKS-RYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTC-EQGPSIVTPPK 167
C C + VCGSD TYPS C LRA ++ A G+ V G C + G P +
Sbjct: 105 TCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLR 164
Query: 168 DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRG 199
+N A V +V V +W ++ G
Sbjct: 165 RNYNFIAAVVE---KVAPSVVHVQLWGRLLHG 193
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 83.6 bits (205), Expect = 2e-16
Identities = 54/161 (33%), Positives = 72/161 (44%), Gaps = 24/161 (14%)
Query: 13 AAGLLLLLLPLSSSSSSDTCGPCEPASCPP--LPPLGCLLGETRDACGCCPMCARGEGEP 70
A LLL L + + PC PA C P C G D C CC +CA EGEP
Sbjct: 3 ARALLLAALAALALAREPPAAPC-PARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEP 61
Query: 71 CGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSG 130
CGG C +ECV+ G+C C+ + VCG+DG TY +
Sbjct: 62 CGGPLDSP--CGESLECVR-------------------GLCRCRWSHAVCGTDGHTYANV 100
Query: 131 CQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN 171
C L+AAS+RA + Q+ KG C G ++ P+ +N
Sbjct: 101 CALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFN 141
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/162 (27%), Positives = 71/162 (43%), Gaps = 12/162 (7%)
Query: 105 PGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQV-SKGTCEQGPSIV 163
P +GV VC++R + G Y + ++ + A + S G+ E P +
Sbjct: 76 PTDAGVYVCRAR----NAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFL 131
Query: 164 TPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGG 223
T P+ W + GA+V L+C G+P P L W K G+ E+ D + A+Q
Sbjct: 132 TGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEK-----DGMALDEV--WDSSHFALQPGRA 184
Query: 224 PEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ + + + D+G Y CHA N+ G A A A + V
Sbjct: 185 EDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226
Score = 52.0 bits (123), Expect = 6e-07
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 16/118 (13%)
Query: 150 QVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELL 209
+ S G P + P+ + V+GA+ L C V+G P PV++W K
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEK-------------- 47
Query: 210 PGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
G + A + P G +L + L DAG Y C A N+ G+A A+A +TV++
Sbjct: 48 -GGQQLAASERLSFPADGAEHGLLLTAAL-PTDAGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 40.4 bits (93), Expect = 0.002
Identities = 55/195 (28%), Positives = 79/195 (40%), Gaps = 34/195 (17%)
Query: 99 GAAAGGPGVS-GVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTC- 156
G A GPG S + + +R P D Y C R A A++ + Q +
Sbjct: 182 GRAEDGPGASLALRILAARLP----DSGVYV--CHARNAHGHAQAGALLQVHQPPESPPA 235
Query: 157 --EQGPS-IVTP----PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELL 209
++ P+ +V P PK W G C V+G P P + W+ R LL
Sbjct: 236 DPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGR--------PLL 287
Query: 210 PGDRDNLAIQTRGGPEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITVVDA 268
P DR L + R G G+VL V +D G Y C A NS GQ ++ ++ V +
Sbjct: 288 P-DRRRLMYRDRDG-------GFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEP 339
Query: 269 LHEI--PVKKGEGAE 281
P++ EG E
Sbjct: 340 RLRFTRPLQDVEGRE 354
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 26/137 (18%)
Query: 131 CQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPV 190
C R A+ ++ A+T ++ P+I P D + G V L+CE G P P
Sbjct: 380 CFARNAAGEVQTSTYLAVTSIA-------PNITRGPLDSTVIDGMSVVLACETSGAPRPA 432
Query: 191 LIWNKVKR--GHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYEC 248
+ W K +R VQ P + +G +L+SP DAG Y C
Sbjct: 433 ITWQKGERILASGSVQLPRFTPLE-----------------SGSLLISPTHISDAGTYTC 475
Query: 249 HASNSQGQASASAKITV 265
A+NS+G ASA + V
Sbjct: 476 LATNSRGVDEASADLVV 492
Score = 33.1 bits (74), Expect = 0.28
Identities = 34/145 (23%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 121 GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS 180
GSD Y LR++S + RG E + P + I V +
Sbjct: 276 GSDAGYYECEAVLRSSSVPSVVRGAYL------SVLEPPQFVKEPERHITAEMEKVVDIP 329
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C+ G+P P + W K V E L R G + +S L
Sbjct: 330 CQAKGVPPPSITWYK----DAAVVEVEKLTRFRQRN-------------DGGLQISGLVP 372
Query: 241 EDAGEYECHASNSQGQASASAKITV 265
+D G ++C A N+ G+ S + V
Sbjct: 373 DDTGMFQCFARNAAGEVQTSTYLAV 397
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 53.9 bits (128), Expect = 2e-07
Identities = 44/125 (35%), Positives = 50/125 (40%), Gaps = 27/125 (21%)
Query: 33 GPCEPASCPPLPPLG--CLLGET------RDACGCCPMCARGEGEPCGGGGAGRGY---- 80
GPC+ A P P LG C G T + AC C C+ CG G G
Sbjct: 459 GPCDQA---PSPCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACEL 515
Query: 81 ----CAPGMECVKSRKRRKGKAGAAAGGP---GVSGVCVCKSR-----YPVCGSDGTTYP 128
C G E +RK + G G +G CVC S PVCGSDG TYP
Sbjct: 516 EATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYP 575
Query: 129 SGCQL 133
S C L
Sbjct: 576 SECML 580
Score = 44.7 bits (104), Expect = 9e-05
Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 17/106 (16%)
Query: 67 EGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRY------PVC 120
E CG GG+G G +C + R++G G CVC PVC
Sbjct: 665 EQAECGSGGSGSGEDG---DCEQELCRQRG---GIWDEDSEDGPCVCDFSCQSVPGSPVC 718
Query: 121 GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPP 166
GSDG TY + C+L+ A R ES ++ + ++G C +GP+ P
Sbjct: 719 GSDGVTYSTECELKKA--RCES--QRGLYVAAQGAC-RGPTFAPLP 759
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 96 GKAGAAAGGPGVSGVCVCKSRY-----PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQ 150
G A A G +G CVC PVCGSDG TY S C+LR A+ +++ E+A
Sbjct: 603 GDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEA--- 659
Query: 151 VSKGTCEQ 158
G CEQ
Sbjct: 660 -RAGPCEQ 666
Score = 43.5 bits (101), Expect = 2e-04
Identities = 41/143 (28%), Positives = 54/143 (37%), Gaps = 18/143 (12%)
Query: 35 CEPASCPPLPPLGCLLGETRDACGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKSRK-- 92
C P SC P + + C C P A G CG GR G E S
Sbjct: 844 CTPCSCDPQGAVRDDCEQMTGLCSCKPGVA---GPKCGQCPDGRALGPAGCEADASAPAT 900
Query: 93 --RRKGKAGAAAGGPGVSGVCVCK-------SRYPVCGSDGTTYPSGCQLRAASQRAESR 143
+ + GA S CVC + VCGSDG TY + CQL+ + R +
Sbjct: 901 CAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGLQ 960
Query: 144 GEKAITQVSKGTCEQGPSIVTPP 166
I+ S G C++ + T P
Sbjct: 961 ----ISIQSLGPCQEAVAPSTHP 979
Score = 42.4 bits (98), Expect = 5e-04
Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 11/61 (18%)
Query: 102 AGGPGVSGVCVCKSR------YPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGT 155
A GPG + CVCK PVCGSD +TY + C+L QRA+ ++ I +S+G
Sbjct: 187 AEGPGRAS-CVCKKSPCPSVVAPVCGSDASTYSNECEL----QRAQCSQQRRIRLLSRGP 241
Query: 156 C 156
C
Sbjct: 242 C 242
Score = 41.6 bits (96), Expect = 8e-04
Identities = 22/50 (44%), Positives = 27/50 (54%), Gaps = 5/50 (10%)
Query: 113 CKSRY-PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPS 161
C Y PVC DG TY S C Q+AE R ++AI +G C+Q PS
Sbjct: 421 CDGAYRPVCAQDGRTYDSDCW----RQQAECRQQRAIPSKHQGPCDQAPS 466
Score = 36.6 bits (83), Expect = 0.025
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 5/47 (10%)
Query: 113 CKSRY-PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQ 158
C S Y PVCGSDG TY S C+L A + + I KG C++
Sbjct: 494 CSSLYDPVCGSDGVTYGSACELEATACTL----GREIQVARKGPCDR 536
Score = 33.5 bits (75), Expect = 0.22
Identities = 48/162 (29%), Positives = 58/162 (35%), Gaps = 48/162 (29%)
Query: 33 GPCEPASCPPLPPLGCLLGET--RDACGC-----CPMCARG--EGEPCGGGGAGRGYCAP 83
GPC S P + C G T R A G CP RG EG CG GA P
Sbjct: 240 GPC--GSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADY----P 293
Query: 84 GMECVKSR----------KRRKGKAGAAAGG-PGVSGVC----------------VCKSR 116
G EC R K+ G G P S C C +R
Sbjct: 294 G-ECQLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPAR 352
Query: 117 Y-PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCE 157
PVCG DG TY + C + + +RG + +V G C+
Sbjct: 353 QAPVCGDDGVTYENDCVM---GRSGAARG-LLLQKVRSGQCQ 390
>gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken)
[Homo sapiens]
Length = 399
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/137 (29%), Positives = 58/137 (42%), Gaps = 26/137 (18%)
Query: 131 CQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPV 190
C R A+ ++ A+T ++ P+I P D + G V L+CE G P P
Sbjct: 192 CFARNAAGEVQTSTYLAVTSIA-------PNITRGPLDSTVIDGMSVVLACETSGAPRPA 244
Query: 191 LIWNKVKR--GHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYEC 248
+ W K +R VQ P + +G +L+SP DAG Y C
Sbjct: 245 ITWQKGERILASGSVQLPRFTPLE-----------------SGSLLISPTHISDAGTYTC 287
Query: 249 HASNSQGQASASAKITV 265
A+NS+G ASA + V
Sbjct: 288 LATNSRGVDEASADLVV 304
Score = 33.1 bits (74), Expect = 0.28
Identities = 34/145 (23%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 121 GSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS 180
GSD Y LR++S + RG E + P + I V +
Sbjct: 88 GSDAGYYECEAVLRSSSVPSVVRGAYL------SVLEPPQFVKEPERHITAEMEKVVDIP 141
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C+ G+P P + W K V E L R G + +S L
Sbjct: 142 CQAKGVPPPSITWYK----DAAVVEVEKLTRFRQRN-------------DGGLQISGLVP 184
Query: 241 EDAGEYECHASNSQGQASASAKITV 265
+D G ++C A N+ G+ S + V
Sbjct: 185 DDTGMFQCFARNAAGEVQTSTYLAV 209
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 52.4 bits (124), Expect = 4e-07
Identities = 40/115 (34%), Positives = 51/115 (44%), Gaps = 15/115 (13%)
Query: 9 LLLGAAGLLLLLL---PLSSSSSSDTCGPCEPAS---CPPLPPLGCLLGETRDACGCCPM 62
++L A LLLL P S S C PC+ + CPP PLGC L + CGCC
Sbjct: 1 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPP-SPLGCELVK-EPGCGCCMT 58
Query: 63 CARGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRY 117
CA EG+ C G CA G+ C+ + K G GVC+ + Y
Sbjct: 59 CALAEGQSC---GVYTERCAQGLRCLPRQDEEKPLHALLHG----RGVCLNEKSY 106
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 52.0 bits (123), Expect = 6e-07
Identities = 30/80 (37%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 9 LLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEG 68
LL+ GLLLLL S + + C PC+ + C P C + CGCC CA
Sbjct: 16 LLVSLLGLLLLLA--RSGTRALVCLPCDESKCEE--PRNCPGSIVQGVCGCCYTCASQRN 71
Query: 69 EPCGGGGAGRGYCAPGMECV 88
E CGG G C G+ CV
Sbjct: 72 ESCGGTFGIYGTCDRGLRCV 91
Score = 28.5 bits (62), Expect = 6.9
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 4/29 (13%)
Query: 35 CEPASCPPLPPLGCLLGETRDACGCCPMC 63
C SCPPLP + + E CCPMC
Sbjct: 849 CSTVSCPPLPCVEPINVEG----SCCPMC 873
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 51.6 bits (122), Expect = 8e-07
Identities = 45/170 (26%), Positives = 59/170 (34%), Gaps = 28/170 (16%)
Query: 97 KAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTC 156
KAGA G G S Y V S + A +R +
Sbjct: 2701 KAGAQLGARG--------SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 2752
Query: 157 EQGPSIVTP-PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDN 215
Q +V P P + V +V L CE GIP P + W K T++LPG
Sbjct: 2753 VQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG---- 2808
Query: 216 LAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + ++ S EDAG Y C A NS G A ++ V
Sbjct: 2809 ---------------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 2843
Score = 44.3 bits (103), Expect = 1e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 130 GCQLRAASQRAESRGEK-AITQVSKGTCEQGPSIVT--PP------KDIWNVTGAQVYLS 180
G QLR A E G I + S G+ +V PP D+ G+ +L
Sbjct: 2808 GGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2867
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C+ G P P + W D+D + G + +G +LV L
Sbjct: 2868 CKARGSPEPNITW------------------DKDGQPVSGAEGKFTIQPSGELLVKNLEG 2909
Query: 241 EDAGEYECHASNSQGQASASAKITVV 266
+DAG Y C A N+ G+A +T++
Sbjct: 2910 QDAGTYTCTAENAVGRARRRVHLTIL 2935
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 24/116 (20%)
Query: 160 PSIVTP--PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLA 217
P+IV P P+ + + Q+ L C V P P + W+ RD +
Sbjct: 2389 PNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWH------------------RDGIV 2430
Query: 218 IQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
+Q + E ++ + LS D+G+Y C A N+ G S + ++ + H +P
Sbjct: 2431 LQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI----HTVP 2482
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 29/116 (25%)
Query: 161 SIVTPPK------DIWNVTGA---QVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPG 211
S++ PP+ + N+T A + L CE +GIP P + W + + + T LL G
Sbjct: 1154 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 1213
Query: 212 DRDNLAIQTRGGPEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITVV 266
GW+L ++ ++D+G Y C ASN G+A + + V+
Sbjct: 1214 -------------------GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 1250
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 27/112 (24%)
Query: 163 VTPPKDIW--NVTGAQ-------VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
V P IW N TG V L CE G+PTP + W K LLP
Sbjct: 306 VHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK---------DGALLP--T 354
Query: 214 DNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ TRGG + + + DAG Y C ASN+ G A + ++ V
Sbjct: 355 STKVVYTRGGRQ-------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 399
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 19/109 (17%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
+ P P+D+ +G V L C+ G PTP + W + + +R LP
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP------ 3168
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + + + DAG Y+C A N G A+A A + V
Sbjct: 3169 -------------DGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3204
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 26/108 (24%)
Query: 177 VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVS 236
+ L CE + P+P + W K + +LLPG T + +
Sbjct: 1368 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPG------------------THGLQIL 1409
Query: 237 PLSKEDAGEYECHASNSQGQASASAKITVV--------DALHEIPVKK 276
KEDAG+Y C +N G+A + + V+ D L E+ VK+
Sbjct: 1410 NAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 1457
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 21/116 (18%)
Query: 155 TCEQGPSIVTPPKD-IWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
T + P+ P + + V G+ + L+C+V G+P P + W K + +P +
Sbjct: 1928 TVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-----------DRMPVES 1976
Query: 214 DNL-AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA 268
+ + +RGG + +S L AG Y C A N+Q +A + V+ A
Sbjct: 1977 SAVHGVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 2024
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P ++ L CE G P P+++W K D L +
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK----------------DGQKLDFR 2616
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ G + + +L++ +D+ ++EC SN G+A ++TV
Sbjct: 2617 LQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV 2662
Score = 37.7 bits (86), Expect = 0.011
Identities = 42/172 (24%), Positives = 59/172 (34%), Gaps = 34/172 (19%)
Query: 127 YPSGCQLRAASQRAESRGEKAITQVSK-GTCEQG--------PSIVTPPKDIWNVTGAQV 177
+P G L AS RA G + VS G Q PSI+ ++ V V
Sbjct: 838 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESV 897
Query: 178 YLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSP 237
L C+ +P PVL W K D ++ R G + V
Sbjct: 898 ALECQSHAMPPPVLSWWK------------------DGRPLEPRPGVHLSADKALLQVDR 939
Query: 238 LSKEDAGEYECHASNSQGQASASAKITV-------VDALHEIPVKKGEGAEL 282
DAG Y C A N G++ + V + H + V++G L
Sbjct: 940 ADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSL 991
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 18/108 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I + P + L C+ G+P P++ W K D + +
Sbjct: 2482 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK------------------DRVPLD 2523
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
R + G + + P+ +DAG Y C ASNS G + V++
Sbjct: 2524 PRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 2571
Score = 36.6 bits (83), Expect = 0.025
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 17/99 (17%)
Query: 167 KDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEK 226
+++ + GA V L C G+PTP + W K R +LPG +L +Q G +
Sbjct: 225 QEVLGLAGADVELQCWTSGVPTPQVEWTK--------DRQPVLPGG-PHLQVQEDG--QV 273
Query: 227 HEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+TG D G Y+C A + GQ + ++ V
Sbjct: 274 LRITG------SHVGDEGRYQCVAFSPAGQQARDFQLRV 306
Score = 36.2 bits (82), Expect = 0.033
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I D A V L+C GIP P + W+K G Q +
Sbjct: 2666 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ-------------LG 2707
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
RG + +G + + AG Y C A NS G A +TV
Sbjct: 2708 ARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2753
Score = 36.2 bits (82), Expect = 0.033
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 25/110 (22%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEV-TGW 232
G + L C V G P P + W K D L + RG +H++ G
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIK------------------DGLPL--RGSHLRHQLQNGS 3081
Query: 233 VLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 282
+ + ++DAG Y+C A N G AK V+ L PV + E ++
Sbjct: 3082 LTIHRTERDDAGRYQCLAENEMG----VAKKVVILVLQSAPVFQVEPQDM 3127
Score = 35.8 bits (81), Expect = 0.043
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 27/117 (23%)
Query: 158 QGPSIVTPPK---DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
Q P ++ P + D+ V G+ V L CE G+P P++ W K D +
Sbjct: 2211 QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK----------------DGE 2254
Query: 215 NLAIQT-RGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH 270
L Q+ GP + + + D+G Y C A + G+A ++TV++ H
Sbjct: 2255 PLLSQSLEQGPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2304
Score = 35.4 bits (80), Expect = 0.057
Identities = 44/176 (25%), Positives = 68/176 (38%), Gaps = 36/176 (20%)
Query: 114 KSRYPVCGSDG--TTYPSGCQLRAASQRAESRG------EKAITQVSKG---TCEQGPSI 162
K PV G++G T PSG +L + + G E A+ + + T P
Sbjct: 2882 KDGQPVSGAEGKFTIQPSG-ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF 2940
Query: 163 VTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRG 222
T P D G +++L C G PTP + W R
Sbjct: 2941 TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR--------------------PVTE 2980
Query: 223 GPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGE 278
G + + + + +S+ED+G Y C A N G+ A + + V +A PV +GE
Sbjct: 2981 GVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA----PVLQGE 3032
Score = 35.0 bits (79), Expect = 0.074
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 18/92 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G + LSCE +P P + W K + QRT+ L RGG +
Sbjct: 1856 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL-----------RGGQR-------L 1897
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ D G Y C SN G+A + +TV
Sbjct: 1898 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1929
Score = 33.9 bits (76), Expect = 0.16
Identities = 14/35 (40%), Positives = 22/35 (62%)
Query: 231 GWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + ++ +S D+G+YEC A+N G S AK+ V
Sbjct: 57 GSLFLASVSPADSGDYECQATNEVGSTSRRAKLVV 91
Score = 32.7 bits (73), Expect = 0.37
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 26/127 (20%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ VT ++I V YL C+ IP P L W + + +L G R
Sbjct: 1559 EEARGGVTEYREI--VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR--- 1613
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSK-EDAGEYECHASNSQGQASASAKITVVDALHEIPVK 275
VL PL + E+AG Y C ASN G+ ++ V+ PV
Sbjct: 1614 ----------------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTP----PVI 1653
Query: 276 KGEGAEL 282
G+ EL
Sbjct: 1654 LGDTEEL 1660
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 23/106 (21%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVT--G 231
G +V L CE G P P + W K D + GP G
Sbjct: 2041 GQEVRLDCEADGQPPPDVAWLK------------------DGSPLGQDMGPHLRFYLDGG 2082
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKG 277
+++ L DAG Y C A N G+ A++ V+ L +K+G
Sbjct: 2083 SLVLKGLRASDAGAYTCVAHNPAGE---DARLHTVNVLVPPTIKQG 2125
Score = 30.0 bits (66), Expect = 2.4
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 18/93 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G +L C V G P P L W K R L GD +++ V V
Sbjct: 1269 GQTAHLMCNVTGHPQPKLTWFKDGR--------PLARGDAHHIS--------PDGVLLQV 1312
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
L + LS AG Y C A+N+ G+ + +++V+
Sbjct: 1313 LQANLS--SAGHYSCIAANAVGEKTKHFQLSVL 1343
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 26/119 (21%)
Query: 172 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG 231
V G V L C G P+P L W+ H G+ E + ++T G + E G
Sbjct: 418 VAGRPVALECVARGHPSPTLSWH-----HEGLPVAE-----SNESRLETDGSVLRLESPG 467
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQA--------SASAKITVVDALHEIPVKKGEGAEL 282
+ +G Y C AS+ G+A ++ V + L ++ G+ EL
Sbjct: 468 --------EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLEL 518
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/128 (22%), Positives = 46/128 (35%), Gaps = 26/128 (20%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN--VTGAQVYLSCEVIGIPTPVLI 192
A S R + T++ G P +T P + + V L+C G P+P L+
Sbjct: 760 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 819
Query: 193 WNKVKRGH----YGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYEC 248
W +K G+ G ++ PG R R D+G Y C
Sbjct: 820 W--LKDGNPVSPAGTPGLQVFPGGRVLTLASARA------------------SDSGRYSC 859
Query: 249 HASNSQGQ 256
A ++ G+
Sbjct: 860 VAVSAVGE 867
Score = 28.5 bits (62), Expect = 6.9
Identities = 34/150 (22%), Positives = 52/150 (34%), Gaps = 31/150 (20%)
Query: 121 GSDGTTYPSGCQLRAASQRAESRGE---KAITQVSKGTCEQGPSIVTPP----------K 167
G + + G L+ RAE+ G KA +V + ++TPP +
Sbjct: 1603 GDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVE 1662
Query: 168 DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKH 227
++ + V L C +G P P + W + R ++L D +Q
Sbjct: 1663 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL---EDGQVLQ-------- 1711
Query: 228 EVTGWVLVSPLSKEDAGEYECHASNSQGQA 257
VS DA Y C A N G A
Sbjct: 1712 -------VSTAEVADAASYMCVAENQAGSA 1734
Score = 28.1 bits (61), Expect = 9.0
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 18/96 (18%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P + + A V L C G+P P + W K GH V + D ++
Sbjct: 695 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLR 751
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQG 255
+ DAG Y C ASN G
Sbjct: 752 ---------------IEQAQLSDAGSYRCVASNVAG 772
Score = 28.1 bits (61), Expect = 9.0
Identities = 30/131 (22%), Positives = 45/131 (34%), Gaps = 29/131 (22%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWN 194
A S+ E+R +T + E P ++ GA + L C+ G P P + W+
Sbjct: 2284 AVSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQGTPQPNITWH 2339
Query: 195 KVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQ 254
K G T L R ++ R DAG Y C A +
Sbjct: 2340 K-----DGQALTRLENNSRATRVLRVR--------------------DAGLYTCLAESPA 2374
Query: 255 GQASASAKITV 265
G S ++ V
Sbjct: 2375 GAIEKSFRVRV 2385
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 51.6 bits (122), Expect = 8e-07
Identities = 45/170 (26%), Positives = 59/170 (34%), Gaps = 28/170 (16%)
Query: 97 KAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTC 156
KAGA G G S Y V S + A +R +
Sbjct: 3892 KAGAQLGARG--------SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 3943
Query: 157 EQGPSIVTP-PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDN 215
Q +V P P + V +V L CE GIP P + W K T++LPG
Sbjct: 3944 VQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG---- 3999
Query: 216 LAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + ++ S EDAG Y C A NS G A ++ V
Sbjct: 4000 ---------------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 4034
Score = 44.3 bits (103), Expect = 1e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 130 GCQLRAASQRAESRGEK-AITQVSKGTCEQGPSIVT--PP------KDIWNVTGAQVYLS 180
G QLR A E G I + S G+ +V PP D+ G+ +L
Sbjct: 3999 GGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 4058
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C+ G P P + W D+D + G + +G +LV L
Sbjct: 4059 CKARGSPEPNITW------------------DKDGQPVSGAEGKFTIQPSGELLVKNLEG 4100
Query: 241 EDAGEYECHASNSQGQASASAKITVV 266
+DAG Y C A N+ G+A +T++
Sbjct: 4101 QDAGTYTCTAENAVGRARRRVHLTIL 4126
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 24/116 (20%)
Query: 160 PSIVTP--PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLA 217
P+IV P P+ + + Q+ L C V P P + W+ RD +
Sbjct: 3580 PNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWH------------------RDGIV 3621
Query: 218 IQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
+Q + E ++ + LS D+G+Y C A N+ G S + ++ + H +P
Sbjct: 3622 LQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI----HTVP 3673
Score = 41.2 bits (95), Expect = 0.001
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 18/109 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P + P+D+ G L+C G P P + W + GD L ++
Sbjct: 786 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRR---------------GDGQPLGLR 830
Query: 220 T---RGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
RG + +G + ++ ED Y C A N G+ A A++ V
Sbjct: 831 LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 29/116 (25%)
Query: 161 SIVTPPK------DIWNVTGA---QVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPG 211
S++ PP+ + N+T A + L CE +GIP P + W + + + T LL G
Sbjct: 2345 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 2404
Query: 212 DRDNLAIQTRGGPEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITVV 266
GW+L ++ ++D+G Y C ASN G+A + + V+
Sbjct: 2405 -------------------GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 2441
Score = 40.0 bits (92), Expect = 0.002
Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 18/92 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G L C G+P P + W K + A+ +RG G +
Sbjct: 990 GVPASLPCVASGVPAPTITWTK------------------ETNALTSRGPHYNVSKEGTL 1031
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
L++ S +DAG Y C A+N+ G +S +++V
Sbjct: 1032 LIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/111 (27%), Positives = 47/111 (42%), Gaps = 24/111 (21%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P + P+ + + G + L+C G P P L W+K D + +Q
Sbjct: 1120 PQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSK------------------DGVVLQ 1161
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH 270
RG P+ G V + + DAG Y C ASNS G + ++ V++ H
Sbjct: 1162 GRG-PQ-----GSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPH 1206
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 27/112 (24%)
Query: 163 VTPPKDIW--NVTGAQ-------VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
V P IW N TG V L CE G+PTP + W K LLP
Sbjct: 1497 VHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK---------DGALLP--T 1545
Query: 214 DNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ TRGG + + + DAG Y C ASN+ G A + ++ V
Sbjct: 1546 STKVVYTRGGRQ-------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 19/109 (17%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
+ P P+D+ +G V L C+ G PTP + W + + +R LP
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP------ 4359
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + + + DAG Y+C A N G A+A A + V
Sbjct: 4360 -------------DGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 4395
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 26/108 (24%)
Query: 177 VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVS 236
+ L CE + P+P + W K + +LLPG T + +
Sbjct: 2559 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPG------------------THGLQIL 2600
Query: 237 PLSKEDAGEYECHASNSQGQASASAKITVV--------DALHEIPVKK 276
KEDAG+Y C +N G+A + + V+ D L E+ VK+
Sbjct: 2601 NAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 2648
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 17/94 (18%)
Query: 172 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG 231
V G L C G P P + W K +E L G + +A+ G
Sbjct: 1219 VAGENASLPCPARGTPKPQVTWRKGPS-------SEPLHG-QPGVAVLEEGS-------- 1262
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ ++ +S D+G+YEC A+N G S AK+ V
Sbjct: 1263 -LFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295
Score = 38.1 bits (87), Expect = 0.009
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 25/112 (22%)
Query: 162 IVTPP--------KDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
++TPP +++ + GA V L C G+PTP + W K R +LPG
Sbjct: 1403 VLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK--------DRQPVLPGG- 1453
Query: 214 DNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+L +Q G + +TG D G Y+C A + GQ + ++ V
Sbjct: 1454 PHLQVQEDG--QVLRITG------SHVGDEGRYQCVAFSPAGQQARDFQLRV 1497
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 21/116 (18%)
Query: 155 TCEQGPSIVTPPKD-IWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
T + P+ P + + V G+ + L+C+V G+P P + W K + +P +
Sbjct: 3119 TVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-----------DRMPVES 3167
Query: 214 DNL-AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA 268
+ + +RGG + +S L AG Y C A N+Q +A + V+ A
Sbjct: 3168 SAVHGVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 3215
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P ++ L CE G P P+++W K D L +
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK----------------DGQKLDFR 3807
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ G + + +L++ +D+ ++EC SN G+A ++TV
Sbjct: 3808 LQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV 3853
Score = 37.4 bits (85), Expect = 0.015
Identities = 21/94 (22%), Positives = 37/94 (39%), Gaps = 19/94 (20%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G +V +SC G PTP + W++ + R + + G +
Sbjct: 622 GVEVKVSCSASGYPTPHISWSRESQALQEDSRIHV-------------------DAQGTL 662
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
++ ++ EDAG Y C A+N G + + D
Sbjct: 663 IIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 696
Score = 37.4 bits (85), Expect = 0.015
Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 23/116 (19%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
PS+ + G + L CE G+P P +IW + G L P
Sbjct: 698 PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIW------YRGGLEMILAP--------- 742
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA--LHEIP 273
+ +G + + + DAG Y C A N G ASA ++ V A L E+P
Sbjct: 743 ------EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELP 792
Score = 37.4 bits (85), Expect = 0.015
Identities = 42/172 (24%), Positives = 58/172 (33%), Gaps = 34/172 (19%)
Query: 127 YPSGCQLRAASQRAESRGEKAITQVSK-GTCEQG--------PSIVTPPKDIWNVTGAQV 177
+P G L AS RA G + VS G Q PSI+ ++ V V
Sbjct: 2029 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESV 2088
Query: 178 YLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSP 237
L C+ +P PVL W K D ++ R G + V
Sbjct: 2089 ALECQSHAMPPPVLSWWK------------------DGRPLEPRPGVHLSADKALLQVDR 2130
Query: 238 LSKEDAGEYECHASNSQGQASASAKITV-------VDALHEIPVKKGEGAEL 282
DAG Y C A N G + + V + H + V++G L
Sbjct: 2131 ADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSL 2182
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 18/108 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I + P + L C+ G+P P++ W K D + +
Sbjct: 3673 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK------------------DRVPLD 3714
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
R + G + + P+ +DAG Y C ASNS G + V++
Sbjct: 3715 PRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 3762
Score = 36.2 bits (82), Expect = 0.033
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I D A V L+C GIP P + W+K G Q +
Sbjct: 3857 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ-------------LG 3898
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
RG + +G + + AG Y C A NS G A +TV
Sbjct: 3899 ARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 3944
Score = 36.2 bits (82), Expect = 0.033
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 25/110 (22%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEV-TGW 232
G + L C V G P P + W K D L + RG +H++ G
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIK------------------DGLPL--RGSHLRHQLQNGS 4272
Query: 233 VLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 282
+ + ++DAG Y+C A N G AK V+ L PV + E ++
Sbjct: 4273 LTIHRTERDDAGRYQCLAENEMG----VAKKVVILVLQSAPVFQVEPQDM 4318
Score = 35.8 bits (81), Expect = 0.043
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 27/117 (23%)
Query: 158 QGPSIVTPPK---DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
Q P ++ P + D+ V G+ V L CE G+P P++ W K D +
Sbjct: 3402 QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK----------------DGE 3445
Query: 215 NLAIQT-RGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH 270
L Q+ GP + + + D+G Y C A + G+A ++TV++ H
Sbjct: 3446 PLLSQSLEQGPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 3495
Score = 35.4 bits (80), Expect = 0.057
Identities = 44/176 (25%), Positives = 68/176 (38%), Gaps = 36/176 (20%)
Query: 114 KSRYPVCGSDG--TTYPSGCQLRAASQRAESRG------EKAITQVSKG---TCEQGPSI 162
K PV G++G T PSG +L + + G E A+ + + T P
Sbjct: 4073 KDGQPVSGAEGKFTIQPSG-ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF 4131
Query: 163 VTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRG 222
T P D G +++L C G PTP + W R
Sbjct: 4132 TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR--------------------PVTE 4171
Query: 223 GPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGE 278
G + + + + +S+ED+G Y C A N G+ A + + V +A PV +GE
Sbjct: 4172 GVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA----PVLQGE 4223
Score = 35.0 bits (79), Expect = 0.074
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 18/92 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G + LSCE +P P + W K + QRT+ L RGG +
Sbjct: 3047 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL-----------RGGQR-------L 3088
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ D G Y C SN G+A + +TV
Sbjct: 3089 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 3120
Score = 32.7 bits (73), Expect = 0.37
Identities = 38/147 (25%), Positives = 57/147 (38%), Gaps = 25/147 (17%)
Query: 129 SGCQLRAASQRAESRGE-KAITQVSKGTCEQGPSIVTPPKDIW---NVT---GAQVYLSC 181
S ++ AS+ E E A+++ G + + PP + NVT G LSC
Sbjct: 479 SSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSC 538
Query: 182 EVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKE 241
V+G L W V+ +LP +A E +S +
Sbjct: 539 RVLGEAPYNLTW---------VRDWRVLPASTGRVAQLADLSLE---------ISGIIPT 580
Query: 242 DAGEYECHASNSQGQASASAKITVVDA 268
D G Y+C ASN+ G AS + V +A
Sbjct: 581 DGGRYQCVASNANGVTRASVWLLVREA 607
Score = 32.7 bits (73), Expect = 0.37
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 26/127 (20%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ VT ++I V YL C+ IP P L W + + +L G R
Sbjct: 2750 EEARGGVTEYREI--VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR--- 2804
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSK-EDAGEYECHASNSQGQASASAKITVVDALHEIPVK 275
VL PL + E+AG Y C ASN G+ ++ V+ PV
Sbjct: 2805 ----------------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTP----PVI 2844
Query: 276 KGEGAEL 282
G+ EL
Sbjct: 2845 LGDTEEL 2851
Score = 30.4 bits (67), Expect = 1.8
Identities = 50/203 (24%), Positives = 73/203 (35%), Gaps = 53/203 (26%)
Query: 65 RGEGEPCGGG-GAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSD 123
RG+G+P G GAGRG SR R+ SGV +S P D
Sbjct: 821 RGDGQPLGLRLGAGRG----------SRSRQPD-----------SGVLFFESVAP---ED 856
Query: 124 GTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEV 183
Y C+ R + ++ +T + P I + + + G V L C V
Sbjct: 857 QAPYV--CEARNVFGKVQAEARLIVTGHAP------PQIASSAPTVRVLEGQPVSLPCIV 908
Query: 184 I-GIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKED 242
+ G P P W K R L PG R ++ G + + +E
Sbjct: 909 LAGRPLPERHWLKDGR--------PLPPGSRHSI-----------RADGSLHLDRALQEH 949
Query: 243 AGEYECHASNSQGQASASAKITV 265
AG Y C A+N+ G ++ V
Sbjct: 950 AGRYSCVATNTAGSQHRDVELVV 972
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 23/106 (21%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVT--G 231
G +V L CE G P P + W K D + GP G
Sbjct: 3232 GQEVRLDCEADGQPPPDVAWLK------------------DGSPLGQDMGPHLRFYLDGG 3273
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKG 277
+++ L DAG Y C A N G+ A++ V+ L +K+G
Sbjct: 3274 SLVLKGLRASDAGAYTCVAHNPAGE---DARLHTVNVLVPPTIKQG 3316
Score = 30.0 bits (66), Expect = 2.4
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 18/93 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G +L C V G P P L W K R L GD +++ V V
Sbjct: 2460 GQTAHLMCNVTGHPQPKLTWFKDGR--------PLARGDAHHIS--------PDGVLLQV 2503
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
L + LS AG Y C A+N+ G+ + +++V+
Sbjct: 2504 LQANLS--SAGHYSCIAANAVGEKTKHFQLSVL 2534
Score = 28.9 bits (63), Expect = 5.3
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 5/53 (9%)
Query: 219 QTRGGPEKHEV----TGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
+ R G E+H + W ++ SK + G YEC A + G A A+I V D
Sbjct: 464 EARLGEERHFQESGNSSWEILRA-SKAEEGTYECTAVSRAGTGRAKAQIVVTD 515
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 26/119 (21%)
Query: 172 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG 231
V G V L C G P+P L W+ H G+ E + ++T G + E G
Sbjct: 1609 VAGRPVALECVARGHPSPTLSWH-----HEGLPVAE-----SNESRLETDGSVLRLESPG 1658
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQA--------SASAKITVVDALHEIPVKKGEGAEL 282
+ +G Y C AS+ G+A ++ V + L ++ G+ EL
Sbjct: 1659 --------EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLEL 1709
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/128 (22%), Positives = 46/128 (35%), Gaps = 26/128 (20%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN--VTGAQVYLSCEVIGIPTPVLI 192
A S R + T++ G P +T P + + V L+C G P+P L+
Sbjct: 1951 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 2010
Query: 193 WNKVKRGH----YGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYEC 248
W +K G+ G ++ PG R R D+G Y C
Sbjct: 2011 W--LKDGNPVSPAGTPGLQVFPGGRVLTLASARA------------------SDSGRYSC 2050
Query: 249 HASNSQGQ 256
A ++ G+
Sbjct: 2051 VAVSAVGE 2058
Score = 28.5 bits (62), Expect = 6.9
Identities = 34/150 (22%), Positives = 52/150 (34%), Gaps = 31/150 (20%)
Query: 121 GSDGTTYPSGCQLRAASQRAESRGE---KAITQVSKGTCEQGPSIVTPP----------K 167
G + + G L+ RAE+ G KA +V + ++TPP +
Sbjct: 2794 GDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVE 2853
Query: 168 DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKH 227
++ + V L C +G P P + W + R ++L D +Q
Sbjct: 2854 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL---EDGQVLQ-------- 2902
Query: 228 EVTGWVLVSPLSKEDAGEYECHASNSQGQA 257
VS DA Y C A N G A
Sbjct: 2903 -------VSTAEVADAASYMCVAENQAGSA 2925
Score = 28.1 bits (61), Expect = 9.0
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 18/96 (18%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P + + A V L C G+P P + W K GH V + D ++
Sbjct: 1886 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLR 1942
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQG 255
+ DAG Y C ASN G
Sbjct: 1943 ---------------IEQAQLSDAGSYRCVASNVAG 1963
Score = 28.1 bits (61), Expect = 9.0
Identities = 30/131 (22%), Positives = 45/131 (34%), Gaps = 29/131 (22%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWN 194
A S+ E+R +T + E P ++ GA + L C+ G P P + W+
Sbjct: 3475 AVSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQGTPQPNITWH 3530
Query: 195 KVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQ 254
K G T L R ++ R DAG Y C A +
Sbjct: 3531 K-----DGQALTRLENNSRATRVLRVR--------------------DAGLYTCLAESPA 3565
Query: 255 GQASASAKITV 265
G S ++ V
Sbjct: 3566 GAIEKSFRVRV 3576
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 51.6 bits (122), Expect = 8e-07
Identities = 45/170 (26%), Positives = 59/170 (34%), Gaps = 28/170 (16%)
Query: 97 KAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTC 156
KAGA G G S Y V S + A +R +
Sbjct: 2610 KAGAQLGARG--------SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLT 2661
Query: 157 EQGPSIVTP-PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDN 215
Q +V P P + V +V L CE GIP P + W K T++LPG
Sbjct: 2662 VQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG---- 2717
Query: 216 LAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + ++ S EDAG Y C A NS G A ++ V
Sbjct: 2718 ---------------GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 2752
Score = 44.3 bits (103), Expect = 1e-04
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 130 GCQLRAASQRAESRGEK-AITQVSKGTCEQGPSIVT--PP------KDIWNVTGAQVYLS 180
G QLR A E G I + S G+ +V PP D+ G+ +L
Sbjct: 2717 GGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2776
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C+ G P P + W D+D + G + +G +LV L
Sbjct: 2777 CKARGSPEPNITW------------------DKDGQPVSGAEGKFTIQPSGELLVKNLEG 2818
Query: 241 EDAGEYECHASNSQGQASASAKITVV 266
+DAG Y C A N+ G+A +T++
Sbjct: 2819 QDAGTYTCTAENAVGRARRRVHLTIL 2844
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 24/116 (20%)
Query: 160 PSIVTP--PKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLA 217
P+IV P P+ + + Q+ L C V P P + W+ RD +
Sbjct: 2298 PNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWH------------------RDGIV 2339
Query: 218 IQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
+Q + E ++ + LS D+G+Y C A N+ G S + ++ + H +P
Sbjct: 2340 LQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEI----HTVP 2391
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 29/116 (25%)
Query: 161 SIVTPPK------DIWNVTGA---QVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPG 211
S++ PP+ + N+T A + L CE +GIP P + W + + + T LL G
Sbjct: 1063 SVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG 1122
Query: 212 DRDNLAIQTRGGPEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITVV 266
GW+L ++ ++D+G Y C ASN G+A + + V+
Sbjct: 1123 -------------------GWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 1159
Score = 39.7 bits (91), Expect = 0.003
Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 27/112 (24%)
Query: 163 VTPPKDIW--NVTGAQ-------VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
V P IW N TG V L CE G+PTP + W K LLP
Sbjct: 215 VHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK---------DGALLP--T 263
Query: 214 DNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ TRGG + + + DAG Y C ASN+ G A + ++ V
Sbjct: 264 STKVVYTRGGRQ-------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 19/109 (17%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
+ P P+D+ +G V L C+ G PTP + W + + +R LP
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP------ 3077
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G + + + DAG Y+C A N G A+A A + V
Sbjct: 3078 -------------DGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVV 3113
Score = 38.5 bits (88), Expect = 0.007
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 26/108 (24%)
Query: 177 VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVS 236
+ L CE + P+P + W K + +LLPG T + +
Sbjct: 1277 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPG------------------THGLQIL 1318
Query: 237 PLSKEDAGEYECHASNSQGQASASAKITVV--------DALHEIPVKK 276
KEDAG+Y C +N G+A + + V+ D L E+ VK+
Sbjct: 1319 NAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKE 1366
Score = 38.1 bits (87), Expect = 0.009
Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 25/112 (22%)
Query: 162 IVTPP--------KDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
++TPP +++ + GA V L C G+PTP + W K R +LPG
Sbjct: 121 VLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK--------DRQPVLPGG- 171
Query: 214 DNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+L +Q G + +TG D G Y+C A + GQ + ++ V
Sbjct: 172 PHLQVQEDG--QVLRITG------SHVGDEGRYQCVAFSPAGQQARDFQLRV 215
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 21/116 (18%)
Query: 155 TCEQGPSIVTPPKD-IWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDR 213
T + P+ P + + V G+ + L+C+V G+P P + W K + +P +
Sbjct: 1837 TVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-----------DRMPVES 1885
Query: 214 DNL-AIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA 268
+ + +RGG + +S L AG Y C A N+Q +A + V+ A
Sbjct: 1886 SAVHGVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVA 1933
Score = 38.1 bits (87), Expect = 0.009
Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P ++ L CE G P P+++W K D L +
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK----------------DGQKLDFR 2525
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ G + + +L++ +D+ ++EC SN G+A ++TV
Sbjct: 2526 LQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTV 2571
Score = 37.4 bits (85), Expect = 0.015
Identities = 42/172 (24%), Positives = 58/172 (33%), Gaps = 34/172 (19%)
Query: 127 YPSGCQLRAASQRAESRGEKAITQVSK-GTCEQG--------PSIVTPPKDIWNVTGAQV 177
+P G L AS RA G + VS G Q PSI+ ++ V V
Sbjct: 747 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESV 806
Query: 178 YLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSP 237
L C+ +P PVL W K D ++ R G + V
Sbjct: 807 ALECQSHAMPPPVLSWWK------------------DGRPLEPRPGVHLSADKALLQVDR 848
Query: 238 LSKEDAGEYECHASNSQGQASASAKITV-------VDALHEIPVKKGEGAEL 282
DAG Y C A N G + + V + H + V++G L
Sbjct: 849 ADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRL 900
Score = 37.0 bits (84), Expect = 0.019
Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 18/108 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I + P + L C+ G+P P++ W K D + +
Sbjct: 2391 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK------------------DRVPLD 2432
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVD 267
R + G + + P+ +DAG Y C ASNS G + V++
Sbjct: 2433 PRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 2480
Score = 36.2 bits (82), Expect = 0.033
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I D A V L+C GIP P + W+K G Q +
Sbjct: 2575 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ-------------LG 2616
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
RG + +G + + AG Y C A NS G A +TV
Sbjct: 2617 ARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2662
Score = 36.2 bits (82), Expect = 0.033
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 25/110 (22%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEV-TGW 232
G + L C V G P P + W K D L + RG +H++ G
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIK------------------DGLPL--RGSHLRHQLQNGS 2990
Query: 233 VLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGEGAEL 282
+ + ++DAG Y+C A N G AK V+ L PV + E ++
Sbjct: 2991 LTIRRTERDDAGRYQCLAENEMG----VAKKVVILVLQSAPVFQVEPQDM 3036
Score = 35.8 bits (81), Expect = 0.043
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 27/117 (23%)
Query: 158 QGPSIVTPPK---DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
Q P ++ P + D+ V G+ V L CE G+P P++ W K D +
Sbjct: 2120 QVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK----------------DGE 2163
Query: 215 NLAIQT-RGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH 270
L Q+ GP + + + D+G Y C A + G+A ++TV++ H
Sbjct: 2164 PLLSQSLEQGPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2213
Score = 35.4 bits (80), Expect = 0.057
Identities = 44/176 (25%), Positives = 68/176 (38%), Gaps = 36/176 (20%)
Query: 114 KSRYPVCGSDG--TTYPSGCQLRAASQRAESRG------EKAITQVSKG---TCEQGPSI 162
K PV G++G T PSG +L + + G E A+ + + T P
Sbjct: 2791 KDGQPVSGAEGKFTIQPSG-ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF 2849
Query: 163 VTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRG 222
T P D G +++L C G PTP + W R
Sbjct: 2850 TTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR--------------------PVTE 2889
Query: 223 GPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKGE 278
G + + + + +S+ED+G Y C A N G+ A + + V +A PV +GE
Sbjct: 2890 GVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA----PVLQGE 2941
Score = 35.0 bits (79), Expect = 0.074
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 18/92 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G + LSCE +P P + W K + QRT+ L RGG +
Sbjct: 1765 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL-----------RGGQR-------L 1806
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ D G Y C SN G+A + +TV
Sbjct: 1807 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1838
Score = 32.7 bits (73), Expect = 0.37
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 26/127 (20%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ VT ++I V YL C+ IP P L W + + +L G R
Sbjct: 1468 EEARGGVTEYREI--VENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGR--- 1522
Query: 217 AIQTRGGPEKHEVTGWVLVSPLSK-EDAGEYECHASNSQGQASASAKITVVDALHEIPVK 275
VL PL + E+AG Y C ASN G+ ++ V+ PV
Sbjct: 1523 ----------------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTP----PVI 1562
Query: 276 KGEGAEL 282
G+ EL
Sbjct: 1563 LGDTEEL 1569
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 23/106 (21%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVT--G 231
G +V L CE G P P + W K D + GP G
Sbjct: 1950 GQEVRLDCEADGQPPPDVAWLK------------------DGSPLGQDMGPHLRFYLDGG 1991
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKKG 277
+++ L DAG Y C A N G+ A++ V+ L +K+G
Sbjct: 1992 SLVLKGLRASDAGAYTCVAHNPAGE---DARLHTVNVLVPPTIKQG 2034
Score = 30.0 bits (66), Expect = 2.4
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 18/93 (19%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G +L C V G P P L W K R L GD +++ V V
Sbjct: 1178 GQTAHLMCNVTGHPQPKLTWFKDGR--------PLARGDAHHIS--------PDGVLLQV 1221
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
L + LS AG Y C A+N+ G+ + +++V+
Sbjct: 1222 LQANLS--SAGHYSCIAANAVGEKTKHFQLSVL 1252
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/119 (24%), Positives = 46/119 (38%), Gaps = 26/119 (21%)
Query: 172 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG 231
V G V L C G P+P L W+ H G+ E + ++T G + E G
Sbjct: 327 VAGRPVALECVARGHPSPTLSWH-----HEGLPVAE-----SNESRLETDGSVLRLESPG 376
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQA--------SASAKITVVDALHEIPVKKGEGAEL 282
+ +G Y C AS+ G+A ++ V + L ++ G+ EL
Sbjct: 377 --------EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLEL 427
Score = 28.9 bits (63), Expect = 5.3
Identities = 29/128 (22%), Positives = 46/128 (35%), Gaps = 26/128 (20%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWN--VTGAQVYLSCEVIGIPTPVLI 192
A S R + T++ G P +T P + + V L+C G P+P L+
Sbjct: 669 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 728
Query: 193 WNKVKRGH----YGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYEC 248
W +K G+ G ++ PG R R D+G Y C
Sbjct: 729 W--LKDGNPVSPAGTPGLQVFPGGRVLTLASARA------------------SDSGRYSC 768
Query: 249 HASNSQGQ 256
A ++ G+
Sbjct: 769 VAVSAVGE 776
Score = 28.5 bits (62), Expect = 6.9
Identities = 34/150 (22%), Positives = 52/150 (34%), Gaps = 31/150 (20%)
Query: 121 GSDGTTYPSGCQLRAASQRAESRGE---KAITQVSKGTCEQGPSIVTPP----------K 167
G + + G L+ RAE+ G KA +V + ++TPP +
Sbjct: 1512 GDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVE 1571
Query: 168 DIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKH 227
++ + V L C +G P P + W + R ++L D +Q
Sbjct: 1572 EVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL---EDGQVLQ-------- 1620
Query: 228 EVTGWVLVSPLSKEDAGEYECHASNSQGQA 257
VS DA Y C A N G A
Sbjct: 1621 -------VSTAEVADAASYMCVAENQAGSA 1643
Score = 28.1 bits (61), Expect = 9.0
Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 18/96 (18%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+I P + + A V L C G+P P + W K GH V + D ++
Sbjct: 604 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLR 660
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQG 255
+ DAG Y C ASN G
Sbjct: 661 ---------------IEQAQLSDAGSYRCVASNVAG 681
Score = 28.1 bits (61), Expect = 9.0
Identities = 30/131 (22%), Positives = 45/131 (34%), Gaps = 29/131 (22%)
Query: 135 AASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWN 194
A S+ E+R +T + E P ++ GA + L C+ G P P + W+
Sbjct: 2193 AVSEAGEARRHFQLTVMEPPHIEDSGQ----PTELSLTPGAPMELLCDAQGTPQPNITWH 2248
Query: 195 KVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQ 254
K G T L R ++ R DAG Y C A +
Sbjct: 2249 K-----DGQALTRLENNSRATRVLRVR--------------------DAGLYTCLAESPA 2283
Query: 255 GQASASAKITV 265
G S ++ V
Sbjct: 2284 GAIEKSFRVRV 2294
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 49.3 bits (116), Expect = 4e-06
Identities = 34/130 (26%), Positives = 52/130 (40%), Gaps = 23/130 (17%)
Query: 140 AESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNK---- 195
A + G + T P P D G L CEV G P P + W +
Sbjct: 460 ASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHI 519
Query: 196 VKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQG 255
+ G + R LL +G + ++P+ +DAG Y C+A+N++G
Sbjct: 520 LASGSVRIPRFMLLE-------------------SGGLQIAPVFIQDAGNYTCYAANTEG 560
Query: 256 QASASAKITV 265
+ASA +TV
Sbjct: 561 SLNASATLTV 570
Score = 35.8 bits (81), Expect = 0.043
Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 19/92 (20%)
Query: 177 VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPE-KHEVTGWVLV 235
V + C+ +G+P P L W K D ++I P K +G + +
Sbjct: 404 VDIGCQAMGVPLPTLQWYK------------------DAISISRLQNPRYKVLASGGLRI 445
Query: 236 SPLSKEDAGEYECHASNSQGQASASAKITVVD 267
L ED+G ++C ASN G+ + V +
Sbjct: 446 QKLRPEDSGIFQCFASNEGGEIQTHTYLDVTN 477
Score = 34.7 bits (78), Expect = 0.097
Identities = 27/112 (24%), Positives = 41/112 (36%), Gaps = 19/112 (16%)
Query: 161 SIVTPPKDIWNVTGAQVYLSCEVIGIPTPVL--IWNKVKRGHYGVQRTELLPGDRDNLAI 218
SIV PP+D + G L C P L +W K L P + +
Sbjct: 575 SIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKK--------DNVALTPSSTSRIVV 626
Query: 219 QTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALH 270
+ G +L+S D G+Y C + G S A++ V++ H
Sbjct: 627 EKDGS---------LLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPH 669
>gi|193083136 leucine-rich repeat, immunoglobulin-like and
transmembrane domains 3 [Homo sapiens]
Length = 634
Score = 48.9 bits (115), Expect = 5e-06
Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 14/107 (13%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
PS++T I + G+ V L C+ G PTP + W + + P + +I
Sbjct: 209 PSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIM 268
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
+ G +S +DAG+Y+C A N G + A +TV+
Sbjct: 269 SLTG--------------ISSKDAGDYKCKAKNLAGMSEAVVTVTVL 301
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 48.5 bits (114), Expect = 6e-06
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 18/112 (16%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ P + PKD V+G C+ G P P + WNK K QR E + D
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNK-KGKKVNSQRFETIEFD---- 84
Query: 217 AIQTRGGPEKHEVTGWVL-VSPL-SKEDAGEYECHASNSQGQASASAKITVV 266
E G VL + PL + D YEC A NS G+ + AK+TV+
Sbjct: 85 -----------ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
Score = 30.8 bits (68), Expect = 1.4
Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 16/92 (17%)
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C G P P + W K + LP D G K +G + + +
Sbjct: 156 CAASGNPDPEITWFK-----------DFLPVDPS-----ASNGRIKQLRSGALQIESSEE 199
Query: 241 EDAGEYECHASNSQGQASASAKITVVDALHEI 272
D G+YEC A+NS G +S V L E+
Sbjct: 200 TDQGKYECVATNSAGVRYSSPANLYVRELREV 231
Score = 28.1 bits (61), Expect = 9.0
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 22/92 (23%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G V ++C +G P P + W +Q E L PE G
Sbjct: 250 GGNVNITCVAVGSPMPYVKW---------MQGAEDLT-------------PEDDMPVGRN 287
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
++ +D+ Y C A +S G A A+ITV
Sbjct: 288 VLELTDVKDSANYTCVAMSSLGVIEAVAQITV 319
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 48.5 bits (114), Expect = 6e-06
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 18/112 (16%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ P + PKD V+G C+ G P P + WNK K QR E + D
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNK-KGKKVNSQRFETIEFD---- 84
Query: 217 AIQTRGGPEKHEVTGWVL-VSPL-SKEDAGEYECHASNSQGQASASAKITVV 266
E G VL + PL + D YEC A NS G+ + AK+TV+
Sbjct: 85 -----------ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
Score = 28.5 bits (62), Expect = 6.9
Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 16/75 (21%)
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C G P P + W K + LP D G K +G + + +
Sbjct: 156 CAASGNPDPEITWFK-----------DFLPVDPS-----ASNGRIKQLRSGALQIESSEE 199
Query: 241 EDAGEYECHASNSQG 255
D G+YEC A+NS G
Sbjct: 200 TDQGKYECVATNSAG 214
Score = 28.1 bits (61), Expect = 9.0
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 22/92 (23%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G V ++C +G P P + W +Q E L PE G
Sbjct: 246 GGNVNITCVAVGSPMPYVKW---------MQGAEDLT-------------PEDDMPVGRN 283
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
++ +D+ Y C A +S G A A+ITV
Sbjct: 284 VLELTDVKDSANYTCVAMSSLGVIEAVAQITV 315
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 48.5 bits (114), Expect = 6e-06
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 18/112 (16%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ P + PKD V+G C+ G P P + WNK K QR E + D
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNK-KGKKVNSQRFETIEFD---- 84
Query: 217 AIQTRGGPEKHEVTGWVL-VSPL-SKEDAGEYECHASNSQGQASASAKITVV 266
E G VL + PL + D YEC A NS G+ + AK+TV+
Sbjct: 85 -----------ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
Score = 28.5 bits (62), Expect = 6.9
Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 16/75 (21%)
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C G P P + W K + LP D G K +G + + +
Sbjct: 156 CAASGNPDPEITWFK-----------DFLPVDPS-----ASNGRIKQLRSGALQIESSEE 199
Query: 241 EDAGEYECHASNSQG 255
D G+YEC A+NS G
Sbjct: 200 TDQGKYECVATNSAG 214
Score = 28.1 bits (61), Expect = 9.0
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 22/92 (23%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G V ++C +G P P + W +Q E L PE G
Sbjct: 246 GGNVNITCVAVGSPMPYVKW---------MQGAEDLT-------------PEDDMPVGRN 283
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
++ +D+ Y C A +S G A A+ITV
Sbjct: 284 VLELTDVKDSANYTCVAMSSLGVIEAVAQITV 315
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 48.5 bits (114), Expect = 6e-06
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 18/112 (16%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNL 216
E+ P + PKD V+G C+ G P P + WNK K QR E + D
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNK-KGKKVNSQRFETIEFD---- 84
Query: 217 AIQTRGGPEKHEVTGWVL-VSPL-SKEDAGEYECHASNSQGQASASAKITVV 266
E G VL + PL + D YEC A NS G+ + AK+TV+
Sbjct: 85 -----------ESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
Score = 29.3 bits (64), Expect = 4.1
Identities = 26/96 (27%), Positives = 37/96 (38%), Gaps = 15/96 (15%)
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGD---RDNLAIQTRGGP-EKHEVTGWVLVS 236
C G P P + W K + LP D + Q R E + G + +
Sbjct: 156 CAASGNPDPEITWFK-----------DFLPVDPSASNGRIKQLRSETFESTPIRGALQIE 204
Query: 237 PLSKEDAGEYECHASNSQGQASASAKITVVDALHEI 272
+ D G+YEC A+NS G +S V L E+
Sbjct: 205 SSEETDQGKYECVATNSAGVRYSSPANLYVRELREV 240
Score = 28.1 bits (61), Expect = 9.0
Identities = 24/92 (26%), Positives = 35/92 (38%), Gaps = 22/92 (23%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G V ++C +G P P + W +Q E L PE G
Sbjct: 259 GGNVNITCVAVGSPMPYVKW---------MQGAEDLT-------------PEDDMPVGRN 296
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
++ +D+ Y C A +S G A A+ITV
Sbjct: 297 VLELTDVKDSANYTCVAMSSLGVIEAVAQITV 328
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 48.5 bits (114), Expect = 6e-06
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 18/136 (13%)
Query: 134 RAASQRAESRGEKAITQVSKGTCEQG---PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPV 190
R S RG + + K ++ P + P D+ G L C+V G+P P
Sbjct: 1044 RLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPE 1103
Query: 191 LIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHA 250
L W + +LP + ++ G +L+ PL++ DAG Y+C A
Sbjct: 1104 LTWL--------LNGQPVLPDASHKMLVRETGVHS-------LLIDPLTQRDAGTYKCIA 1148
Query: 251 SNSQGQASASAKITVV 266
+N GQ S S +++VV
Sbjct: 1149 TNKTGQNSFSLELSVV 1164
Score = 48.1 bits (113), Expect = 8e-06
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 19/103 (18%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGW- 232
G V L C VIG+P PV W K E +P R+ +++ + TG+
Sbjct: 1186 GHPVRLECRVIGMPPPVFYWKK---------DNETIPCTRERISMH-------QDTTGYA 1229
Query: 233 -VLVSPLSKEDAGEYECHASNSQGQASASAKITV-VDALHEIP 273
+L+ P K DAG Y A N G S +A++ + H+IP
Sbjct: 1230 CLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIP 1272
Score = 36.6 bits (83), Expect = 0.025
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 24/96 (25%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G +V L C V+GIP P + W + + P+ H V
Sbjct: 283 GTRVQLDCIVVGIPPPQVRWYCEGK--------------------ELENSPDIHIVQAGN 322
Query: 234 L----VSPLSKEDAGEYECHASNSQGQASASAKITV 265
L ++ +ED G Y C ASN G S SA+I +
Sbjct: 323 LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
Score = 33.9 bits (76), Expect = 0.16
Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 14/92 (15%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G+ V +C+++GIP P + W K G +R E R+ + T +
Sbjct: 959 GSPVTFTCKIVGIPVPKVYW--FKDGKQISKRNEHCKMRREG------------DGTCSL 1004
Query: 234 LVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ + +D G Y A+N QG+ S S + V
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 31.2 bits (69), Expect = 1.1
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 12/94 (12%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQT--RGGPEKHEVTG 231
G V C V G P+P + W + L+ D +Q R E E+
Sbjct: 449 GQLVVFECRVKGAPSPKVEWYR---------EGTLIEDSPDFRILQKKPRSMAEPEEICT 499
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
V+ + ED+G + C ASN G S+ A++ V
Sbjct: 500 LVIAEVFA-EDSGCFTCTASNKYGTVSSIAQLHV 532
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 48.1 bits (113), Expect = 8e-06
Identities = 59/236 (25%), Positives = 84/236 (35%), Gaps = 46/236 (19%)
Query: 32 CGP----CEPASCPPLPPL-----GCLLGETRDACGCCPMCARGEGEPCGGGGAGRGY-- 80
CGP C C P L C G CG P C E PCG G
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPPPPCEPNEF-PCGNGHCALKLWR 343
Query: 81 CAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRA 140
C +C + R +A C K VCG S AS
Sbjct: 344 CDGDFDC----EDRTDEAN-----------CPTKRPEEVCGPTQFRCVSTNMCIPASFHC 388
Query: 141 ESRGEKAITQVSKGTCEQGPSIVTPPKD-IWNVTGAQVYLSCEVIGIPTPVLIWNKVKRG 199
+ + G P +VTPP++ I G V +C IG+PTP++ W ++ G
Sbjct: 389 DEESDCPDRSDEFGCMP--PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINW-RLNWG 445
Query: 200 HYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQG 255
H +P + + + GG G +++ + + D G Y C A N++G
Sbjct: 446 H--------IP-SHPRVTVTSEGG------RGTLIIRDVKESDQGAYTCEAMNARG 486
Score = 37.4 bits (85), Expect = 0.015
Identities = 19/48 (39%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 221 RGG--PEKHEVTGWVLVSP-LSKEDAGEYECHASNSQGQASASAKITV 265
RGG P +H++ G L P ++ D+GEY CH SN G S +T+
Sbjct: 2570 RGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTI 2617
Score = 37.4 bits (85), Expect = 0.015
Identities = 43/164 (26%), Positives = 60/164 (36%), Gaps = 41/164 (25%)
Query: 105 PGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVT 164
P SG VC+ V GS G S E+ G A+ + G P I
Sbjct: 2785 PADSGEYVCR----VMGSSGPLEAS------VLVTIEASGSSAVHVPAPGGA---PPIRI 2831
Query: 165 PPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGG- 223
P G + L C V G + W+K RGG
Sbjct: 2832 EPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK-------------------------RGGN 2866
Query: 224 -PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITV 265
P +H+V G +L ++ +S D+GEY C + S G AS +T+
Sbjct: 2867 LPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI 2910
Score = 36.6 bits (83), Expect = 0.025
Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 19/115 (16%)
Query: 159 GPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAI 218
GP + P+ G V L C G+P+ + W K + +L
Sbjct: 1955 GPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRK----------------EGGSLPP 1998
Query: 219 QTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
Q R E+ ++ +L+ ++ DAG Y C A++ G A A ++ V+ A P
Sbjct: 1999 QARS--ERTDIAT-LLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASP 2050
Score = 36.6 bits (83), Expect = 0.025
Identities = 24/103 (23%), Positives = 42/103 (40%), Gaps = 22/103 (21%)
Query: 163 VTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRG 222
++ P+++ G+ C G PTP + W+K+ LP
Sbjct: 3578 ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGS---------LP------------ 3616
Query: 223 GPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
P+ +++ + +DAG Y C A+N QG+ A A + V
Sbjct: 3617 -PDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 36.2 bits (82), Expect = 0.033
Identities = 35/141 (24%), Positives = 58/141 (41%), Gaps = 30/141 (21%)
Query: 122 SDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQG-PSIVTPPKDIWNVTGAQVYLS 180
SD TY C + A A+ + E V G G P + ++ G L
Sbjct: 3178 SDAGTYV--CLAQNALGTAQKQVEVI---VDTGAMAPGAPQVQAEEAELTVEAGHTATLR 3232
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSP-LS 239
C G P P + W+K+ R+ L P +H + G L+ P ++
Sbjct: 3233 CSATGSPAPTIHWSKL--------RSPL---------------PWQHRLEGDTLIIPRVA 3269
Query: 240 KEDAGEYECHASNSQGQASAS 260
++D+G+Y C+A++ G A A+
Sbjct: 3270 QQDSGQYICNATSPAGHAEAT 3290
Score = 35.4 bits (80), Expect = 0.057
Identities = 45/164 (27%), Positives = 63/164 (38%), Gaps = 39/164 (23%)
Query: 115 SRYPVCGS-----DGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDI 169
SR+ + GS T SG + S A SR I + PS V+PP I
Sbjct: 2576 SRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPS-VSPPIRI 2634
Query: 170 WN-----VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGG- 223
+ V G + L+C V P ++ W K RGG
Sbjct: 2635 ESSSPTVVEGQTLDLNCVVARQPQAIITWYK-------------------------RGGS 2669
Query: 224 -PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITV 265
P +H+ G L + +S D+GEY C A+N+ AS I+V
Sbjct: 2670 LPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713
Score = 35.4 bits (80), Expect = 0.057
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 23/101 (22%)
Query: 172 VTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTG 231
V G V C +G P P + W+KV GH L PG I GG
Sbjct: 3501 VVGHAVEFECLALGDPKPQVTWSKVG-GH-------LRPG------IVQSGGV------- 3539
Query: 232 WVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEI 272
V ++ + DAG+Y C A+N+ G + S + +V AL +I
Sbjct: 3540 -VRIAHVELADAGQYRCTATNAAG-TTQSHVLLLVQALPQI 3578
Score = 33.5 bits (75), Expect = 0.22
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 221 RGG--PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITV 265
RGG P +H+ G +L + ++ D+GEY CH + G AS +T+
Sbjct: 2188 RGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235
Score = 33.1 bits (74), Expect = 0.28
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 221 RGG--PEKHEVTGWVLVSP-LSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
RGG P +V G L P +S D+GEY C N G AS ++V+ H P
Sbjct: 2087 RGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGP 2142
Score = 33.1 bits (74), Expect = 0.28
Identities = 25/103 (24%), Positives = 38/103 (36%), Gaps = 16/103 (15%)
Query: 163 VTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRG 222
V P +W G V L C G P W ++ +++ +T G
Sbjct: 3116 VLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQ-------------RTYG 3162
Query: 223 GPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ H V + +S DAG Y C A N+ G A ++ V
Sbjct: 3163 LMDSHAV---LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIV 3202
Score = 32.7 bits (73), Expect = 0.37
Identities = 29/111 (26%), Positives = 38/111 (34%), Gaps = 26/111 (23%)
Query: 157 EQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYG--VQRTELLPGDRD 214
E P T P+ G V L C G P W++V G R ELL +R
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFER- 3354
Query: 215 NLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+ ED+G Y C +N G A A A++ V
Sbjct: 3355 -----------------------AAPEDSGRYRCRVTNKVGSAEAFAQLLV 3382
Score = 31.6 bits (70), Expect = 0.82
Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 221 RGG--PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITVVDAL 269
RGG P +H+V G L + ++ D+GEY C S G AS +T+ L
Sbjct: 2473 RGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRL 2524
Score = 31.2 bits (69), Expect = 1.1
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 4/47 (8%)
Query: 221 RGG--PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKIT 264
RGG P +H+V G L + S DAG+Y C ASN +AS + +T
Sbjct: 2281 RGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGM-EASITVTVT 2326
Score = 30.8 bits (68), Expect = 1.4
Identities = 30/127 (23%), Positives = 42/127 (33%), Gaps = 24/127 (18%)
Query: 140 AESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRG 199
A +G + + GT P + P + G C G PTP L W G
Sbjct: 1847 AMDQGTATLHVQASGTLS-APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGG 1905
Query: 200 HYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSP-LSKEDAGEYECHASNSQGQAS 258
P K ++ G +L P + D +Y C A +S GQ
Sbjct: 1906 QL----------------------PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQV 1943
Query: 259 ASAKITV 265
A A + V
Sbjct: 1944 ARAVLHV 1950
Score = 30.8 bits (68), Expect = 1.4
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 221 RGG--PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQGQASASAKITV 265
RGG P H+ G L + +S D+GEY C S G AS +T+
Sbjct: 2763 RGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI 2810
Score = 28.5 bits (62), Expect = 6.9
Identities = 36/143 (25%), Positives = 51/143 (35%), Gaps = 40/143 (27%)
Query: 139 RAESRGEKAITQVSKGTCEQGPSIVTP----------PKDIWNVTGAQVYLSCEVIGIPT 188
RA + E +IT GT QG ++ P P G + L+C V G
Sbjct: 2312 RASNGMEASITVTVTGT--QGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSH 2369
Query: 189 PVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGG--PEKHEVTGWVL-VSPLSKEDAGE 245
+ W+K RGG P +H+ G +L + S D+GE
Sbjct: 2370 AQVTWHK-------------------------RGGSLPVRHQTHGSLLRLYQASPADSGE 2404
Query: 246 YECHASNSQGQASASAKITVVDA 268
Y C S AS +T+ A
Sbjct: 2405 YVCRVLGSSVPLEASVLVTIEPA 2427
Score = 28.5 bits (62), Expect = 6.9
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)
Query: 221 RGG--PEKHEVTGWVL-VSPLSKEDAGEYECHASNSQG-QASASAKITV 265
RGG P +H+ G L + +S D+GEY C A++ G + AS +TV
Sbjct: 2961 RGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTV 3009
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 48.1 bits (113), Expect = 8e-06
Identities = 42/137 (30%), Positives = 55/137 (40%), Gaps = 21/137 (15%)
Query: 152 SKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPG 211
+K T PS P D+ GA L C +G P P + W K G
Sbjct: 595 AKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQK--------------DG 640
Query: 212 DRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA--- 268
D A + R E + +V + ED G Y C A NS G SA+A +TV++
Sbjct: 641 GTDFPAARERRMHVMPEDDVFFIVD-VKIEDIGVYSCTAQNSAGSISANATLTVLETPSF 699
Query: 269 ---LHEIPVKKGEGAEL 282
L + V KGE A L
Sbjct: 700 LRPLLDRTVTKGETAVL 716
Score = 31.6 bits (70), Expect = 0.82
Identities = 25/112 (22%), Positives = 40/112 (35%), Gaps = 18/112 (16%)
Query: 155 TCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
T + PS + P D G L C G P P L W K +R G++
Sbjct: 692 TVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ- 750
Query: 215 NLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
+++ DAG+Y C SN+ G + +++V+
Sbjct: 751 -----------------LLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVI 785
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 48.1 bits (113), Expect = 8e-06
Identities = 42/137 (30%), Positives = 55/137 (40%), Gaps = 21/137 (15%)
Query: 152 SKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPG 211
+K T PS P D+ GA L C +G P P + W K G
Sbjct: 535 AKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQK--------------DG 580
Query: 212 DRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA--- 268
D A + R E + +V + ED G Y C A NS G SA+A +TV++
Sbjct: 581 GTDFPAARERRMHVMPEDDVFFIVD-VKIEDIGVYSCTAQNSAGSISANATLTVLETPSF 639
Query: 269 ---LHEIPVKKGEGAEL 282
L + V KGE A L
Sbjct: 640 LRPLLDRTVTKGETAVL 656
Score = 31.6 bits (70), Expect = 0.82
Identities = 25/112 (22%), Positives = 40/112 (35%), Gaps = 18/112 (16%)
Query: 155 TCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
T + PS + P D G L C G P P L W K +R G++
Sbjct: 632 TVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ- 690
Query: 215 NLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVV 266
+++ DAG+Y C SN+ G + +++V+
Sbjct: 691 -----------------LLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVI 725
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 19/106 (17%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P + P D GA V L C G P P + WNK GVQ TE
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-----GVQVTE------------ 567
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G G++ ++ + DAG YEC A N+ G AS S ++V
Sbjct: 568 --SGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 42.7 bits (99), Expect = 4e-04
Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 19/106 (17%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P P+D + G V CE G P PV+ W K G Q L DR +L +
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK-----GGSQ----LSVDRRHLVLS 483
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
+G + +S ++ D G+YEC A N G A +TV
Sbjct: 484 ----------SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 519
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 19/115 (16%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
P+ V P++ + G V L C G P P + W + GDR L +
Sbjct: 342 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR---------------GDRTPLPVD 386
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPV 274
R +G + + + + D+GEY C A+N+ A+A I +V AL + V
Sbjct: 387 PR---VNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFI-IVQALPQFTV 437
Score = 37.0 bits (84), Expect = 0.019
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 126 TYPSGCQLRAAS-----QRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLS 180
TY +AA+ +R + R IT + CE+ P I + P+D +G VY +
Sbjct: 209 TYAESGNAQAAAICEYPRRIQGRSVATITP-EELNCER-PRITSEPQDADVTSGNTVYFT 266
Query: 181 CEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSK 240
C G P P +IW + + + L+++T + G +++ +
Sbjct: 267 CRAEGNPKPEIIWLR----------------NNNELSMKTDSRLNLLD-DGTLMIQNTQE 309
Query: 241 EDAGEYECHASNSQGQ 256
D G Y+C A N G+
Sbjct: 310 TDQGIYQCMAKNVAGE 325
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 27/143 (18%)
Query: 149 TQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGV---QR 205
+Q +K T + PS + P D+ TGA L C G P P + W K + +R
Sbjct: 591 SQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERR 650
Query: 206 TELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
++P D ++ + ED G Y C A N+ G SA+A +TV
Sbjct: 651 MHVMPED------------------DVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTV 692
Query: 266 VDA------LHEIPVKKGEGAEL 282
++ L + V +GE A L
Sbjct: 693 LETPSFIRPLEDKTVTRGETAVL 715
Score = 32.3 bits (72), Expect = 0.48
Identities = 28/120 (23%), Positives = 40/120 (33%), Gaps = 30/120 (25%)
Query: 155 TCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNK------VKRGHYGVQRTEL 208
T + PS + P +D G L C G P P L W K V H+ +L
Sbjct: 691 TVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQL 750
Query: 209 LPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDA 268
L ++ EDAG+Y C SN+ G + V+ +
Sbjct: 751 L------------------------IIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISS 786
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 47.4 bits (111), Expect = 1e-05
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 160 PSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQ 219
PS+ P ++ G + ++C+ G P P++ W KV + G R + + +
Sbjct: 260 PSVHVQPLELTANLGEDLRVACQASGYPQPLVTWRKVPQPREGRPRAQ---AQLEGGLLG 316
Query: 220 TRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITV 265
G +G + +S ++ AG+YEC ASN+ G A ++ V
Sbjct: 317 LGGHSASDTGSGMLFLSNITLAHAGKYECEASNAGGAARVPFRLLV 362
>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
[Homo sapiens]
Length = 785
Score = 47.4 bits (111), Expect = 1e-05
Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G+ V C+V P P + W K H V +++ P + + I G + V
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLK----HIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV 325
Query: 234 L-VSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
L + +S EDAGEY C A NS G + SA +TV++AL E P
Sbjct: 326 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 366
Score = 30.4 bits (67), Expect = 1.8
Identities = 42/180 (23%), Positives = 61/180 (33%), Gaps = 26/180 (14%)
Query: 105 PGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRAE------SRGEKAITQVSKGTCEQ 158
P SG+ C + P GSD T + S + S EK
Sbjct: 93 PADSGLYACVTSSP-SGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNRMPV 151
Query: 159 GPSIVTPPK---DIWNVTGAQ-VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRD 214
P +P K + V A+ V C G P P L W +K G E P R
Sbjct: 152 APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRW--LKNGK------EFKPDHRI 203
Query: 215 NLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPV 274
GG + T +++ + D G Y C N G + + ++ VV+ P+
Sbjct: 204 -------GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPI 256
>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
[Homo sapiens]
Length = 731
Score = 47.4 bits (111), Expect = 1e-05
Identities = 35/101 (34%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 174 GAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWV 233
G+ V C+V P P + W K H V +++ P + + I G + V
Sbjct: 179 GSNVEFMCKVYSDPQPHIQWLK----HIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV 234
Query: 234 L-VSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIP 273
L + +S EDAGEY C A NS G + SA +TV++AL E P
Sbjct: 235 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 275
Score = 29.3 bits (64), Expect = 4.1
Identities = 24/98 (24%), Positives = 36/98 (36%), Gaps = 15/98 (15%)
Query: 177 VYLSCEVIGIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVS 236
V C G P P L W +K G E P R GG + T +++
Sbjct: 83 VKFKCPSSGTPNPTLRW--LKNGK------EFKPDHRI-------GGYKVRYATWSIIMD 127
Query: 237 PLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPV 274
+ D G Y C N G + + ++ VV+ P+
Sbjct: 128 SVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPI 165
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.135 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,689,238
Number of Sequences: 37866
Number of extensions: 776386
Number of successful extensions: 5026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 231
Number of HSP's that attempted gapping in prelim test: 2903
Number of HSP's gapped (non-prelim): 1728
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.