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Search of human proteins with 4503173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503173 coxsackie virus and adenovirus receptor precursor
[Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 734 0.0
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 179 3e-45
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 177 1e-44
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 174 9e-44
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 141 1e-33
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 137 2e-32
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 121 9e-28
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 119 3e-27
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 104 1e-22
gi|8393638 F11 receptor precursor [Homo sapiens] 71 1e-12
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 70 3e-12
gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens] 61 1e-09
gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens] 61 1e-09
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 61 2e-09
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 59 7e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 59 9e-09
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 58 1e-08
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 57 3e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 57 3e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 57 3e-08
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 55 1e-07
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 55 1e-07
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 54 2e-07
gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo... 54 2e-07
gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Hom... 54 2e-07
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo... 54 2e-07
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur... 54 2e-07
gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2 precu... 54 2e-07
gi|6005958 V-set and immunoglobulin domain containing 4 isoform ... 53 5e-07
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 53 5e-07
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 734 bits (1895), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS 60
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS
Sbjct: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS 60
Query: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC 120
PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC
Sbjct: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC 120
Query: 121 KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD 180
KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD
Sbjct: 121 KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD 180
Query: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA 240
SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA
Sbjct: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA 240
Query: 241 GAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS 300
GAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS
Sbjct: 241 GAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS 300
Query: 301 SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSK 360
SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSK
Sbjct: 301 SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSK 360
Query: 361 DGSIV 365
DGSIV
Sbjct: 361 DGSIV 365
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 179 bits (454), Expect = 3e-45
Identities = 122/366 (33%), Positives = 187/366 (51%), Gaps = 19/366 (5%)
Query: 8 VLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKV 67
+LL + A SL ++ I+ A+G+ A LPC FT S L++ W+++P N
Sbjct: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALIN-LNVIWMVTPLSNANQ 69
Query: 68 DQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPG 127
+ +ILY G +++D P GRV FT + + + SI + N QLSD GTYQC V P
Sbjct: 70 PEQVILYQGGQMFDGA-PRFHGRVGFTGT-MPATNVSIFINNTQLSDTGTYQCLVNNLPD 127
Query: 128 VANKKIH---LVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKM 184
+ + I L VLV PS C + GS++IGSD + C +EG Y W+KL ++ K+
Sbjct: 128 IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKL 187
Query: 185 PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPS-NKAGLIAGAI 243
P + + ++++N S+ SG Y C N +G+ CLL L V+ P GLIAGAI
Sbjct: 188 PPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAI 247
Query: 244 -IGTLLALALIGLII---FCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTA--RSYIGS 297
G ++ + I LI+ F R K +EE+ E+E+ ++IRED PPK ++ A S
Sbjct: 248 GTGAVIIIFCIALILGAFFYWRSKNKEEE-EEEIPNEIREDDLPPKCSSAKAFHTEISSS 306
Query: 298 NHSSLGSMSPSNMEGYS---KTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVM 354
++++L S + N +S K N F QS + P++ G +
Sbjct: 307 DNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGT--HL 364
Query: 355 IPAQSK 360
+P Q K
Sbjct: 365 VPGQHK 370
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 177 bits (450), Expect = 1e-44
Identities = 120/357 (33%), Positives = 183/357 (51%), Gaps = 19/357 (5%)
Query: 17 ARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSG 76
A SL ++ I+ A+G+ A LPC FT S L++ W+++P N + +ILY G
Sbjct: 19 AASLEVSESPGSIQVARGQPAVLPCTFTTSAALIN-LNVIWMVTPLSNANQPEQVILYQG 77
Query: 77 DKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIH-- 134
+++D P GRV FT + + + SI + N QLSD GTYQC V P + + I
Sbjct: 78 GQMFDGA-PRFHGRVGFTGT-MPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVT 135
Query: 135 -LVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT 193
L VLV PS C + GS++IGSD + C +EG Y W+KL ++ K+P + +
Sbjct: 136 GLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV 195
Query: 194 SSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPS-NKAGLIAGAI-IGTLLALA 251
++++N S+ SG Y C N +G+ CLL L V+ P GLIAGAI G ++ +
Sbjct: 196 QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIF 255
Query: 252 LIGLII---FCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTA--RSYIGSNHSSLGSMS 306
I LI+ F R K +EE+ E+E+ ++IRED PPK ++ A S++++L S +
Sbjct: 256 CIALILGAFFYWRSKNKEEE-EEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSN 314
Query: 307 PSNMEGYS---KTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSK 360
N +S K N F QS + P++ G ++P Q K
Sbjct: 315 AYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGT--HLVPGQHK 369
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 174 bits (442), Expect = 9e-44
Identities = 120/378 (31%), Positives = 189/378 (50%), Gaps = 28/378 (7%)
Query: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS 60
M+LLL +L+ V ++ T E I++ E LPC L ++ LDIEWL++
Sbjct: 1 MSLLLLLLLVSYYVG-----TLGTHTE-IKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLT 54
Query: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC 120
DN+ +V+I YS +Y++ + KGRV F SN L +GDAS+ + L+ SD G Y C
Sbjct: 55 --DNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFL-AGDASLQIEPLKPSDEGRYTC 111
Query: 121 KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKL-- 178
KVK + + L VLV+PS +C ++G GSD ++CE G+ P+ Y WQ++
Sbjct: 112 KVKNSGRYVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIRE 171
Query: 179 ---SDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNK 235
D + P S + + ++N + YSG Y CT N G + C++R+ V
Sbjct: 172 KEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCVVRV-TVQYVQS 230
Query: 236 AGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVH-HDIREDVPPPKSRTSTARSY 294
G++AGA+ G + LI L+++ +++ +E+YE+E ++IRED PK+R S
Sbjct: 231 IGMVAGAVTGIVAGALLIFLLVWLLIRRKDKERYEEEERPNEIREDAEAPKARLVKPSSS 290
Query: 295 IGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPT------------LPPAKVAA 342
+ SS S + S ++ + S D P T P KV
Sbjct: 291 SSGSRSSRSGSSSTRSTANSASRSQRTLSTDAAPQPGLATQAYSLVGPEVRGSEPKKVHH 350
Query: 343 PNLSRMGAIPVMIPAQSK 360
NL++ P MIP+QS+
Sbjct: 351 ANLTKAETTPSMIPSQSR 368
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 141 bits (355), Expect = 1e-33
Identities = 90/267 (33%), Positives = 136/267 (50%), Gaps = 36/267 (13%)
Query: 26 EEMIEKAKGETAYLPCKFTLSPEDQGP--LDIEWL---ISPADNQKVDQVIILYSGDKIY 80
+E++ A+G+ L C + L PED GP LDIEW+ PA ++ + V + Y +I
Sbjct: 29 QEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHHR--ENVFLSYQDKRIN 86
Query: 81 DDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVK 140
P L+ RV F ++D DASIN+ NLQ+SD TY+C+VKK +A +K+ + V +
Sbjct: 87 HGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT-MATRKVIVTVQAR 145
Query: 141 PSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLS--------------DSQKMPT 186
P+ C+ +G G+D +KC GS PL Y+W K+S S
Sbjct: 146 PAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSEL 205
Query: 187 SWLAEMTSSV--------ISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
S+ SS+ + +K+ S G Y CTV N VG C++ + V S + G+
Sbjct: 206 SYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVK-VSDSRRIGV 264
Query: 239 IAGAIIGTLLALALI-----GLIIFCC 260
I G ++G+LLAL + GL+ CC
Sbjct: 265 IIGIVLGSLLALGCLAVGIWGLVCCCC 291
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 137 bits (344), Expect = 2e-32
Identities = 94/316 (29%), Positives = 158/316 (50%), Gaps = 23/316 (7%)
Query: 10 LCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQ 69
LC V ++S+ TP++++ ++G++ LPC + S + L I+W ++
Sbjct: 12 LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQW--DKLLLTHTER 68
Query: 70 VIILYSGDK--IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVK---K 124
V+I +K I+ + Y K RV SN+ + DASI + L ++D GTY+C V
Sbjct: 69 VVIWPFSNKNYIHGELY---KNRVSI-SNNAEQSDASITIDQLTMADNGTYECSVSLMSD 124
Query: 125 APGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD-SQK 183
G ++ L+VLV PS C ++G IG++ ++ C+ KEGS QY W++ + +Q+
Sbjct: 125 LEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQE 184
Query: 184 MPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAI 243
P + A + +S+KN S++ SG Y CT N G+ C + + V PS L G
Sbjct: 185 QPLAQPA--SGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIA 242
Query: 244 IGTLLALALIGLIIFCC----RKKRREEKYEKEVHHDIREDVPPPKSRTSTAR----SYI 295
+G + AL +IG+II+CC + E+K + + + E+ P S R Y
Sbjct: 243 VGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYR 302
Query: 296 GSNHSSLGSMSPSNME 311
S G SP +++
Sbjct: 303 QEEQRSTGRESPDHLD 318
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 121 bits (304), Expect = 9e-28
Identities = 103/374 (27%), Positives = 176/374 (47%), Gaps = 42/374 (11%)
Query: 20 LSITTPEEMIEKAKGETAYLPCKFTLSPE--DQGPLDIEWLI-SPADNQKVDQVIILYSG 76
L + P ++ +G LP +TL E P ++ +++ +K DQV+ +G
Sbjct: 31 LQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQPWEVPFVMWFFKQKEKEDQVLSYING 90
Query: 77 DKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVK------KAPGVAN 130
K V + + S + S+ + LQ D G Y C V K+ G +
Sbjct: 91 -------VTTSKPGVSLVYS-MPSRNLSLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSI 142
Query: 131 KKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLA 190
K + L VLV P+ C + G +G++ + C+ +QY+W + S + +
Sbjct: 143 KTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAVQYQWDRQLPSFQTFFAPAL 202
Query: 191 EMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLAL 250
++ +S+ N SS +G Y C N VG+ QC + L V A ++AGA++GTL+ L
Sbjct: 203 DVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEVSTGPG-AAVVAGAVVGTLVGL 261
Query: 251 ALI-GLIIFCCRKKRREEKYEKEVHHDIRED------VPPPKSRTSTARSYIGSNHSSL- 302
L+ GL++ R+ + E E +DI+ED +P PKS + +++ S+ +S
Sbjct: 262 GLLAGLVLLYHRRGKALE----EPANDIKEDAIAPRTLPWPKSSDTISKNGTLSSVTSAR 317
Query: 303 -----------GSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAI 351
G+++P+ ++P+ D PQ + P V++ LSRMGA+
Sbjct: 318 ALRPPHGPPRPGALTPTPSLSSQALPSPRLPTTDGAH-PQPISPIPGGVSSSGLSRMGAV 376
Query: 352 PVMIPAQSKDGSIV 365
PVM+PAQS+ GS+V
Sbjct: 377 PVMVPAQSQAGSLV 390
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 119 bits (299), Expect = 3e-27
Identities = 89/289 (30%), Positives = 132/289 (45%), Gaps = 19/289 (6%)
Query: 4 LLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEW-LISPA 62
LL F+ L G+ ++ + P E + G+TA L C ++ S D L EW + P
Sbjct: 13 LLGFLCLSGL-----AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFAL--EWSFVQPG 65
Query: 63 DNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKV 122
I+ ++ +Y RV N G A++ +T++ SD GTY C+V
Sbjct: 66 KPISESHPILYFTNGHLYPT--GSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQV 123
Query: 123 KKAPGVANKK---IHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLS 179
P I+L VLV PS C G +G ++C EG+ Y W +L
Sbjct: 124 NNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLG 183
Query: 180 D-SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
P S + + S + + N S SGTY C N++GS C L L+V PS G
Sbjct: 184 TFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ--GR 241
Query: 239 IAGAIIGTLLALALIGLIIFCCRKKRREE-KYEKEVH--HDIREDVPPP 284
+AGA+IG LL + L+ + FC + ++E K KE + D+RED P
Sbjct: 242 VAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAP 290
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 104 bits (260), Expect = 1e-22
Identities = 88/355 (24%), Positives = 153/355 (43%), Gaps = 26/355 (7%)
Query: 7 FVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQK 66
F++L + + +T P+ + G L C +T + + L I+W +
Sbjct: 9 FLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEME 68
Query: 67 VDQVIILYSGDKIYDDYYPD-LKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKA 125
+ G + + D + G SND G+ASI ++++Q +D G Y C V
Sbjct: 69 PISIYFSQGGQAVAIGQFKDRITG-----SND--PGNASITISHMQPADSGIYICDVNNP 121
Query: 126 PGVANKK---IHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQ 182
P + +++ VLVKPS C V G E G + C G+ Y W KL
Sbjct: 122 PDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRD 181
Query: 183 KMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGA 242
+P T+ ++ + N ++ G Y CT NR+G+ C + L P + G+I GA
Sbjct: 182 IVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP--EVGIIVGA 239
Query: 243 IIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPK-SRTSTARSYIGSNHSS 301
+IG+L+ A+I + + C + + + K ++ I E P K + + + + +
Sbjct: 240 LIGSLVGAAII-ISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQ 298
Query: 302 LGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIP 356
L PS++ +T + + D+E PT PA AP G+ P+ +P
Sbjct: 299 LEVTLPSSIH---ETGPDTIQEPDYE---PKPTQEPAPEPAP-----GSEPMAVP 342
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 71.2 bits (173), Expect = 1e-12
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 44/273 (16%)
Query: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFT--LSPEDQGPLDIEWL 58
+ L + +LLC + S+++ + E + + L C ++ SP +EW
Sbjct: 12 LCLFILAILLCSLA--LGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPR------VEWK 63
Query: 59 ISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTY 118
D + ++ Y+ +KI Y + RV F L +G +VT D GTY
Sbjct: 64 FDQGDTTR----LVCYN-NKITASY----EDRVTF----LPTGITFKSVTR---EDTGTY 107
Query: 119 QCKVKKAPG--VANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQ 176
C V + G K+ L+VLV PS + S IG+ + C ++GS P +Y W
Sbjct: 108 TCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWF 167
Query: 177 KLSDSQKMPT-----------SWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLL 225
K D MPT S++ T+ + S+ +G YSC RN G+
Sbjct: 168 K--DGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSN 225
Query: 226 RLNVVPPSNKAGLIAGAIIGTLLALALIGLIIF 258
+ + G+I A++ TL+ L+G+++F
Sbjct: 226 AVRMEAVERNVGVIVAAVLVTLI---LLGILVF 255
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 70.1 bits (170), Expect = 3e-12
Identities = 67/288 (23%), Positives = 125/288 (43%), Gaps = 39/288 (13%)
Query: 1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLIS 60
+ LLL ++++ A S ++++ + + A L CK +P+ +EW
Sbjct: 10 LLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACK---TPKKTVSSRLEW--- 63
Query: 61 PADNQKVDQ-VIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ 119
+K+ + V +Y + D+ N + D +I + N+ SD G Y+
Sbjct: 64 ----KKLGRSVSFVYYQQTLQGDF-----------KNRAEMIDFNIRIKNVTRSDAGKYR 108
Query: 120 CKV----KKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW 175
C+V ++ + + L VLV P+ C V S G+ +++C+ KEG+ +Y W
Sbjct: 109 CEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTW 168
Query: 176 QKLS---------DSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLR 226
K SQ +S+ + + S +G YSC RN VG +C +
Sbjct: 169 FKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK 228
Query: 227 LNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKK---RREEKYEK 271
V N +G+IA A++ L +++ GL + ++K +E ++K
Sbjct: 229 RMQVDDLNISGIIA-AVVVVALVISVCGLGVCYAQRKGYFSKETSFQK 275
>gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens]
Length = 209
Score = 61.2 bits (147), Expect = 1e-09
Identities = 42/136 (30%), Positives = 60/136 (44%), Gaps = 12/136 (8%)
Query: 19 SLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDK 78
+L + TP+E+ A G L CKF + G + W P + YS +
Sbjct: 37 ALEVYTPKEIFV-ANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSFFHYSQGQ 94
Query: 79 IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL 138
+Y YP K R+ + + DL DASIN+ N+Q GTY C VK P ++
Sbjct: 95 VYLGNYPPFKDRISW-AGDLDKKDASINIENMQFIHNGTYICDVKNPPD---------IV 144
Query: 139 VKPSGARCYVDGSEEI 154
V+P R YV E +
Sbjct: 145 VQPGHIRLYVVEKENL 160
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 12/92 (13%)
Query: 187 SWLAEMTS--SVISVKNASSEYSGTYSCTVRN--RVGSDQCLLRLNVVPPSN-------- 234
SW ++ + I+++N ++GTY C V+N + +RL VV N
Sbjct: 108 SWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWV 167
Query: 235 KAGLIAGAIIGTLLALALIGLIIFCCRKKRRE 266
G++ ++G L +++I +++ + +R+
Sbjct: 168 VVGIVTAVVLGLTLLISMILAVLYRRKNSKRD 199
>gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]
Length = 269
Score = 61.2 bits (147), Expect = 1e-09
Identities = 42/136 (30%), Positives = 60/136 (44%), Gaps = 12/136 (8%)
Query: 19 SLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDK 78
+L + TP+E+ A G L CKF + G + W P + YS +
Sbjct: 37 ALEVYTPKEIFV-ANGTQGKLTCKFKSTSTTGGLTSVSWSFQP-EGADTTVSFFHYSQGQ 94
Query: 79 IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL 138
+Y YP K R+ + + DL DASIN+ N+Q GTY C VK P ++
Sbjct: 95 VYLGNYPPFKDRISW-AGDLDKKDASINIENMQFIHNGTYICDVKNPPD---------IV 144
Query: 139 VKPSGARCYVDGSEEI 154
V+P R YV E +
Sbjct: 145 VQPGHIRLYVVEKENL 160
Score = 30.4 bits (67), Expect = 2.6
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 12/92 (13%)
Query: 187 SWLAEMTS--SVISVKNASSEYSGTYSCTVRN--RVGSDQCLLRLNVVPPSN-------- 234
SW ++ + I+++N ++GTY C V+N + +RL VV N
Sbjct: 108 SWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWV 167
Query: 235 KAGLIAGAIIGTLLALALIGLIIFCCRKKRRE 266
G++ ++G L +++I +++ + +R+
Sbjct: 168 VVGIVTAVVLGLTLLISMILAVLYRRKNSKRD 199
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 60.8 bits (146), Expect = 2e-09
Identities = 63/269 (23%), Positives = 117/269 (43%), Gaps = 20/269 (7%)
Query: 9 LLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVD 68
LL D ++IT+P +I G++A L +++ + D+ P+ ++W + V
Sbjct: 23 LLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDR-PV-VKWQLKRDKPVTVV 80
Query: 69 QVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPG- 127
Q I G ++ PD + R+ N S+ +++LQL+D GTY+ ++
Sbjct: 81 QSI----GTEVIGTLRPDYRDRIRLFEN------GSLLLSDLQLADEGTYEVEISITDDT 130
Query: 128 -VANKKIHLVVLVKPSGARCYVDGSE--EIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKM 184
K I+L V V S + V + E+ F + C + G+ P Y W K
Sbjct: 131 FTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKP-SYTWLKDGKPLLN 189
Query: 185 PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCL-LRLNVVPPSNKAGLIAGAI 243
+ L V+++ E YSC V N + + L +++ V S+ +++
Sbjct: 190 DSRMLLSPDQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYIILSTG- 248
Query: 244 IGTLLALALIGLIIFCCRKKRREEKYEKE 272
G L + L+ + KR+++K EK+
Sbjct: 249 -GIFLLVTLVTVCACWKPSKRKQKKLEKQ 276
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 58.9 bits (141), Expect = 7e-09
Identities = 43/191 (22%), Positives = 85/191 (44%), Gaps = 8/191 (4%)
Query: 107 VTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKE 166
+T++++ D G Y C + + G + L VL PS D +G ++C+
Sbjct: 659 ITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCK-AT 717
Query: 167 GSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLR 226
G+ P + W K + + ++ V+N +E +G Y+C + N +G+++ +
Sbjct: 718 GNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQ 777
Query: 227 LNVVPPS------NKAGLIAGAIIGTLLALALIGL-IIFCCRKKRREEKYEKEVHHDIRE 279
L+V+P + G+ A++ +++ +L+ + II+ RKK E +
Sbjct: 778 LSVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETVVPP 837
Query: 280 DVPPPKSRTST 290
DVP S T
Sbjct: 838 DVPSYLSSQGT 848
Score = 32.7 bits (73), Expect = 0.53
Identities = 39/155 (25%), Positives = 59/155 (38%), Gaps = 15/155 (9%)
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDI-----GTYQCKVKKAPGVA-NKKIHLVVLV 139
D++ VH + D G+ T L L + G YQC + G + K L V V
Sbjct: 541 DMENFVHVHAQD---GEVMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNV 597
Query: 140 KPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEM----TSS 195
PS + D + + +++C P Q WQK P + M
Sbjct: 598 LPSFTKTPHDITIRTTTMARLECAATGHPNP-QIAWQK-DGGTDFPAARERRMHVMPDDD 655
Query: 196 VISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVV 230
V + + + +G YSCT +N GS L V+
Sbjct: 656 VFFITDVKIDDAGVYSCTAQNSAGSISANATLTVL 690
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 58.5 bits (140), Expect = 9e-09
Identities = 53/216 (24%), Positives = 90/216 (41%), Gaps = 38/216 (17%)
Query: 24 TPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDY 83
T E +E A G++ L C+ +PE + + W Y GD
Sbjct: 6083 TELEPLEAAVGDSVSLQCQVAGTPE----ITVSW----------------YKGDT---KL 6119
Query: 84 YPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV---LVK 140
P + R +FT+N A++ + ++D G Y CK + + G A+ K + +
Sbjct: 6120 RPTPEYRTYFTNNV-----ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLP 6174
Query: 141 PSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSV 196
PS AR D + +G + C GS P+Q W + L D + + TS++ + +
Sbjct: 6175 PSFARQLKDIEQTVGLPVTLTCR-LNGSAPIQVCWYRDGVLLRDDENLQTSFVDNV--AT 6231
Query: 197 ISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPP 232
+ + +SG YSC+ N +G+ RL P
Sbjct: 6232 LKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 6267
Score = 55.8 bits (133), Expect = 6e-08
Identities = 53/215 (24%), Positives = 87/215 (40%), Gaps = 38/215 (17%)
Query: 27 EMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPD 86
E ++ + G++A L C+ +PE + + W Y GD P
Sbjct: 7968 EPVKVSVGDSASLQCQLAGTPE----IGVSW----------------YKGDT---KLRPT 8004
Query: 87 LKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL---VKPSG 143
++HF +N A++ + ++D G Y CK + + G + L V + PS
Sbjct: 8005 TTYKMHFRNNV-----ATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSF 8059
Query: 144 ARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISV 199
+R D E +G C GS P+ W K L DS + TS+L ++ +++
Sbjct: 8060 SRQLRDVQETVGLPVVFDCAIS-GSEPISVSWYKDGKPLKDSPNVQTSFLDN--TATLNI 8116
Query: 200 KNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSN 234
+G YSCT N +GS RL + N
Sbjct: 8117 FKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN 8151
Score = 53.5 bits (127), Expect = 3e-07
Identities = 56/219 (25%), Positives = 87/219 (39%), Gaps = 42/219 (19%)
Query: 25 PEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYY 84
P E +E GE A L CK +PE + I W ++ K+
Sbjct: 7025 PLEHVEAVIGEPATLQCKVDGTPE----IRISWY---KEHTKLRSA-------------- 7063
Query: 85 PDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVK---P 141
P K + K+ AS+ + + SD+G Y CK + G LV+ + P
Sbjct: 7064 PAYKMQ-------FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPP 7116
Query: 142 SGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVI 197
AR D E +G +C GS PLQ W K L D + TS++ + + +
Sbjct: 7117 FFARKLKDVHETLGFPVAFECR-INGSEPLQVSWYKDGVLLKDDANLQTSFVHNV--ATL 7173
Query: 198 SVKNASSEYSGTYSCTVRNRVG----SDQCLLRLNVVPP 232
+ + G Y+C+ N +G S + +L + VPP
Sbjct: 7174 QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 7212
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 19/139 (13%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPG------VANKKIHLVVLVKPSGARCYVDGSEEIGSD 157
S+ V NL+L D Y CKV G + K LVKP + D + E +
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAI 5352
Query: 158 FKIKCEPKEGSLPLQYEWQKLSDSQKM---PTSWLA-EMTSSVISVKNASSEYSGTYSCT 213
K G+ P + +W K D ++ P ++ E ++S +++ + + +G Y+C
Sbjct: 5353 LK-------GTPPFKIKWFK--DDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCH 5403
Query: 214 VRNRVGSDQCLLRLNVVPP 232
V N VGSD C L V P
Sbjct: 5404 VTNDVGSDSCTTMLLVTEP 5422
Score = 50.4 bits (119), Expect = 2e-06
Identities = 36/140 (25%), Positives = 61/140 (43%), Gaps = 8/140 (5%)
Query: 99 KSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDF 158
K D S+++ NL+ SD+G Y CK G + P + D S IG
Sbjct: 6509 KHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAV 6568
Query: 159 KIKCEPKEGSLPLQYEWQK-----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCT 213
+++ EG P+ W K + +S+ S++ + + + AS+ SG Y C
Sbjct: 6569 ELRA-IVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASN--SGKYICQ 6625
Query: 214 VRNRVGSDQCLLRLNVVPPS 233
++N G +C L V+ P+
Sbjct: 6626 IKNDAGMRECSAVLTVLEPA 6645
Score = 49.3 bits (116), Expect = 5e-06
Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 10/137 (7%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV---LVKPSGARCYVDGSEEIGSDFK 159
AS+ + ++SD G Y +VK + G +N + + V +V PS R D + +G+
Sbjct: 6700 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVV 6759
Query: 160 IKCEPKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVR 215
++C GS P+ W ++ K +S+ + + +S+ S +G Y+C
Sbjct: 6760 LECR-VSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSD--TGIYTCVAA 6816
Query: 216 NRVGSDQCLLRLNVVPP 232
N GSD+C L V P
Sbjct: 6817 NVAGSDECSAVLTVQEP 6833
Score = 48.5 bits (114), Expect = 9e-06
Identities = 36/134 (26%), Positives = 55/134 (41%), Gaps = 8/134 (5%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ ++NL + D G Y CK G + L+++ KP + I ++C+
Sbjct: 3608 LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQV 3667
Query: 165 KEGSLPLQYEWQKLSDSQKMPT----SWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
E + W K D QK+P E + + + A + SGTY CT N GS
Sbjct: 3668 DE-DRKVTVTWSK--DGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGS 3724
Query: 221 DQCLLRLNV-VPPS 233
C + V PPS
Sbjct: 3725 SSCSATVTVREPPS 3738
Score = 48.5 bits (114), Expect = 9e-06
Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A + + N+ +S G Y C V G A+ L V + + D S E G ++
Sbjct: 5948 AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILE- 6006
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS----VISVKNASSEYSGTYSCTVRNRV 218
G+LP+ W+K D + TS + ++ ++ + N++ +G YSC + N
Sbjct: 6007 STYTGTLPISVTWKK--DGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEA 6064
Query: 219 GSDQCLLRLNVVPP 232
G D C ++ + P
Sbjct: 6065 GRDVCGALVSTLEP 6078
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/133 (22%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCE 163
SI++ N+ +DIG YQCK G + + P + D S +G + +++
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQ-T 7513
Query: 164 PKEGSLPLQYEWQKLSDS--QKMPTSWLAEMTS-SVISVKNASSEYSGTYSCTVRNRVGS 220
EG+ P+ W K ++ W++ + + + +G Y+C ++N G
Sbjct: 7514 TIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGM 7573
Query: 221 DQCLLRLNVVPPS 233
+C L+V+ P+
Sbjct: 7574 QECFATLSVLEPA 7586
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/136 (27%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDFKI 160
A++ + +L D GTY C G ++ + V PS + VD S + G ++
Sbjct: 3699 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVK-KVDPSYLMLPGESARL 3757
Query: 161 KCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRN 216
C+ K GS +Q W K LS+S + ++ + +++ + + E SG+YSC N
Sbjct: 3758 HCKLK-GSPVIQVTWFKNNKELSESNTVRMYFVN--SEAILDITDVKVEDSGSYSCEAVN 3814
Query: 217 RVGSDQCLLRLNVVPP 232
VGSD C + + P
Sbjct: 3815 DVGSDSCSTEIVIKEP 3830
Score = 47.0 bits (110), Expect = 3e-05
Identities = 58/236 (24%), Positives = 95/236 (40%), Gaps = 45/236 (19%)
Query: 12 GVVDFARSLSITTPEEMIEKAK------GETAYLPCKFTLSPEDQGPLDIEWLISPADNQ 65
G+ + +LS+ P ++EK + G+T L C +PE L +W +
Sbjct: 7572 GMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPE----LSTKWFKDGKE-- 7625
Query: 66 KVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKA 125
L S +K ++ + G + + N+ SD G Y +V+
Sbjct: 7626 -------LTSDNKYKISFFNKVSG---------------LKIINVAPSDSGVYSFEVQNP 7663
Query: 126 PGVANKKIHLVV---LVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW----QKL 178
G + L V V PS R + + GS ++C+ GS P+ W ++
Sbjct: 7664 VGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFHEGNEI 7722
Query: 179 SDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPS 233
S +K T+ L + T + ++V SG Y+C N GSD+C L V PPS
Sbjct: 7723 SSGRKYQTT-LTDNTCA-LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPS 7776
Score = 46.6 bits (109), Expect = 4e-05
Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 3/124 (2%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A + + NL + D G Y C+ A G A+ L V P + G+D ++C
Sbjct: 7361 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLEC 7420
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSW--LAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
E +G+ P W K + + ++E + I + N + G Y C N VGS
Sbjct: 7421 E-LQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479
Query: 221 DQCL 224
D C+
Sbjct: 7480 DTCV 7483
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 12/135 (8%)
Query: 107 VTNLQLSDI-----GTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIK 161
VT L+L ++ G Y C V G A+ HL V + + D S E GS ++
Sbjct: 6888 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLE 6947
Query: 162 CEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
G+ P+ W K +S S++ + + S+++ + ++ E YSC + N
Sbjct: 6948 AT-YTGTPPISVSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYAQYSCLIENE 7004
Query: 218 VGSDQCLLRLNVVPP 232
G D C ++V+ P
Sbjct: 7005 AGQDICEALVSVLEP 7019
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 13/140 (9%)
Query: 101 GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDF 158
G AS+ + + ++D G + C+ + G + L+V PS GS+++ GS
Sbjct: 4166 GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVT--KPGSKDVLPGSAV 4223
Query: 159 KIKCEPKEGSLPLQYEWQK-----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCT 213
+K +GS PL W K +S T E + + VK + S GTY+C
Sbjct: 4224 CLK-STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDS---GTYTCK 4279
Query: 214 VRNRVGSDQCLLRLNVVPPS 233
V N G +C L V P+
Sbjct: 4280 VSNVAGGVECSANLFVKEPA 4299
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 13/141 (9%)
Query: 89 GRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYV 148
G + T L+S S+ + ++ SD GTY CKV G +L V +P+ +
Sbjct: 4250 GSCYITKEALES---SLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK-EPATFVEKL 4305
Query: 149 DGSEEI--GSDFKIKCEPKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNA 202
+ S+ + G ++ C+ G+ P++ W +++ +S K S++ +++V+ + +
Sbjct: 4306 EPSQLLKKGDATQLACKVT-GTPPIKITWFANDREIKESSKHRMSFVE--STAVLRLTDV 4362
Query: 203 SSEYSGTYSCTVRNRVGSDQC 223
E SG Y C +N GSD C
Sbjct: 4363 GIEDSGEYMCEAQNEAGSDHC 4383
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSD 157
L+ A + + ++ S G Y C V G A+ HL + + D S E G
Sbjct: 7825 LEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKP 7884
Query: 158 FKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCT 213
++ G+ P+ W+K ++ SQ+ + + S+++ + +++ E +G Y+C
Sbjct: 7885 LILE-GTFTGTPPISVTWKKNGINVTPSQRCNITTTEK--SAILEIPSSTVEDAGQYNCY 7941
Query: 214 VRNRVGSDQCLLRLNVVPP 232
+ N G D C ++ ++ P
Sbjct: 7942 IENASGKDSCSAQILILEP 7960
Score = 43.5 bits (101), Expect = 3e-04
Identities = 54/237 (22%), Positives = 100/237 (42%), Gaps = 45/237 (18%)
Query: 10 LCGVVDFARSLSITTPEEMIEKA-------KGETAYLPCKFTLSPEDQGPLDIEWLISPA 62
+ G V+ + +L + P +EK KG+ L CK T +P P+ I W A
Sbjct: 4283 VAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTP----PIKITWF---A 4335
Query: 63 DNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKV 122
+++++ + K R+ F + A + +T++ + D G Y C+
Sbjct: 4336 NDREIKE----------------SSKHRMSFVEST-----AVLRLTDVGIEDSGEYMCEA 4374
Query: 123 KKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPK-EGSLPLQYEWQK---- 177
+ G + +V+VK S E+ ++ + + G+ P + W K
Sbjct: 4375 QNEAG--SDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTI 4432
Query: 178 LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPS 233
L +K T ++ + S+ +K +++ +G Y C V N VGS C R+ + PPS
Sbjct: 4433 LRSGRKYKT-FIQDHLVSLQILKFVAAD-AGEYQCRVTNEVGSSICSARVTLREPPS 4487
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/242 (21%), Positives = 96/242 (39%), Gaps = 42/242 (17%)
Query: 19 SLSITTPEEMIEKAKGETAYL--PCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSG 76
++ + P + K T P + S E P+ ++WL + ++
Sbjct: 5603 TVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE--------VIRES 5654
Query: 77 DKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLV 136
+ I R+ F N A++ + ++ G Y C++K G+ L+
Sbjct: 5655 ENI----------RITFVENV-----ATLQFAKAEPANAGKYICQIKNDGGMRENMATLM 5699
Query: 137 VLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEM 192
VL + +G ++C+ G+ L EW K L+ SQK S+ ++
Sbjct: 5700 VLEPAVIVEKAGPMTVTVGETCTLECKVA-GTPELSVEWYKDGKLLTSSQKHKFSFYNKI 5758
Query: 193 TSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV----VPPS------NKAGLIAGA 242
+S + + + + +GTY+ V+N VG C ++V VPPS N G++ +
Sbjct: 5759 SS--LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGAS 5816
Query: 243 II 244
I
Sbjct: 5817 CI 5818
Score = 43.1 bits (100), Expect = 4e-04
Identities = 34/135 (25%), Positives = 61/135 (45%), Gaps = 10/135 (7%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL---VKPSGARCYVDGSEEIGSDFKIK 161
+ + + + D G Y +V+ G ++ K + VL + PS + GS ++
Sbjct: 4636 LKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLE 4695
Query: 162 CEPKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
C GS P+ +W Q++S S+K S+ ++ + + SGTY+C+ N+
Sbjct: 4696 CIVA-GSHPISIQWFKDDQEISASEKYKFSF--HDNTAFLEISQLEGTDSGTYTCSATNK 4752
Query: 218 VGSDQCLLRLNVVPP 232
G +QC L V P
Sbjct: 4753 AGHNQCSGHLTVKEP 4767
Score = 42.4 bits (98), Expect = 7e-04
Identities = 29/129 (22%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFK 159
+ +A +++T++++ D G+Y C+ G + +V+ PS + G++
Sbjct: 3790 NSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNAL 3849
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS----VISVKNASSEYSGTYSCTVR 215
++CE G+ P + W K D +++ +S + S + + + +S G Y C V
Sbjct: 3850 LQCEVS-GTGPFEISWFK--DKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVA 3906
Query: 216 NRVGSDQCL 224
N VG C+
Sbjct: 3907 NEVGKCGCM 3915
Score = 42.0 bits (97), Expect = 9e-04
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 7/134 (5%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A I + NL D G + C+ + G + ++V P + ++ ++C
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC 5538
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTS----SVISVKNASSEYSGTYSCTVRNRV 218
E G+ P + W K D +++ +S ++ S + I + N + G Y C +N V
Sbjct: 5539 E-LSGTPPFEVVWYK--DKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEV 5595
Query: 219 GSDQCLLRLNVVPP 232
GSD C+ + + P
Sbjct: 5596 GSDTCVCTVKLKEP 5609
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/134 (21%), Positives = 59/134 (44%), Gaps = 7/134 (5%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCE 163
++++T SD G YQC V G + + + PS + + + + S +
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQ-S 5069
Query: 164 PKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG 219
GS P+ W K L + + S++ + + + +++ + +SG Y+C +N G
Sbjct: 5070 TVAGSPPISITWLKDDQILDEDDNVYISFVDSVAT--LQIRSVDNGHSGRYTCQAKNESG 5127
Query: 220 SDQCLLRLNVVPPS 233
++C L V P+
Sbjct: 5128 VERCYAFLLVQEPA 5141
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 10/137 (7%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL---VKPSGARCYVDGSEEIGSDFK 159
A++ + S IG Y C G A+ L++ V P V +G
Sbjct: 7171 ATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGT 7230
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT----SSVISVKNASSEYSGTYSCTVR 215
KC G+ P++ W K D++++ +MT ++ ++V +G Y+C
Sbjct: 7231 FKCHVT-GTAPIKITWAK--DNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYAS 7287
Query: 216 NRVGSDQCLLRLNVVPP 232
N G D C +L V P
Sbjct: 7288 NIAGKDSCSAQLGVQEP 7304
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 18/139 (12%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV------LVKPSGARCYVDGSEEIGSD 157
S+ + + +D GTY C++ G A K L V + KPS +G
Sbjct: 4824 SLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTT--- 4880
Query: 158 FKIKCEPKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCT 213
+C+ G+ ++ W +++ QK S++ + + IS A E SGTY C
Sbjct: 4881 --FECQIT-GTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQIS--GARVENSGTYVCE 4935
Query: 214 VRNRVGSDQCLLRLNVVPP 232
RN G+ C + L V P
Sbjct: 4936 ARNDAGTASCSIELKVKEP 4954
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 14/142 (9%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLV---KPSGARCYVDGSEEIGSDFK 159
A++N+ S G Y C G A+ L++ P +G
Sbjct: 8112 ATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESAD 8171
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT----SSVISVKNASSEYSGTYSCTVR 215
+C G+ P++ W K DS+++ + +++ S+ ++V SG Y+C
Sbjct: 8172 FECHVT-GTQPIKVSWAK--DSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAV 8228
Query: 216 NRVGSDQCLLRLNV----VPPS 233
N VG D C +LN+ +PPS
Sbjct: 8229 NEVGKDSCTAQLNIKERLIPPS 8250
Score = 39.7 bits (91), Expect = 0.004
Identities = 50/229 (21%), Positives = 91/229 (39%), Gaps = 44/229 (19%)
Query: 19 SLSITTPEEMIEKAKGETAYLPCKFTLSPEDQG--PLDIEWLISPADNQKVDQVIILYSG 76
S+++ P ++K + + + L +G P+ + W D+ I+
Sbjct: 7485 SIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWF--------KDKGEIVRES 7536
Query: 77 DKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLV 136
D I+ Y ++ A++ + ++ ++ G Y C++K G+ L
Sbjct: 7537 DNIWISYSENI---------------ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLS 7581
Query: 137 VLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSW 188
VL + V+ E I G ++C G+ L +W K L+ K S+
Sbjct: 7582 VLEPAT----IVEKPESIKVTTGDTCTLECTVA-GTPELSTKWFKDGKELTSDNKYKISF 7636
Query: 189 LAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV----VPPS 233
+++ + + N + SG YS V+N VG D C L V VPPS
Sbjct: 7637 FNKVSG--LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPS 7683
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/138 (27%), Positives = 60/138 (43%), Gaps = 11/138 (7%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV---LVKPSGARCYVDGSEEI-GSDF 158
A + V + D G Y C G + L + L+ PS + + EE G+ F
Sbjct: 8208 AHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSF 8267
Query: 159 KIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT----SSVISVKNASSEYSGTYSCTV 214
K++ GS P+ W K ++ + PTS E+T + V+ V+ A +G Y+C V
Sbjct: 8268 KLEGRVA-GSQPITVAWYK-NNIEIQPTS-NCEITFKNNTLVLQVRKAGMNDAGLYTCKV 8324
Query: 215 RNRVGSDQCLLRLNVVPP 232
N GS C + + P
Sbjct: 8325 SNDAGSALCTSSIVIKEP 8342
Score = 38.5 bits (88), Expect = 0.010
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 28/196 (14%)
Query: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGD----------------AS 104
P+ +K++ L G + LKG + T LK D AS
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQ---ATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 4542
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ ++ +++ G Y C+ K G+ ++ ++ VK S ++ +
Sbjct: 4543 LYLSGIEVKHDGKYVCQAKNDAGI--QRCSALLSVKEPATITEEAVSIDVTQGDPATLQV 4600
Query: 165 K-EGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEY--SGTYSCTVRNRVGSD 221
K G+ + +W K + + + +T +V +K S+E SG Y+ V+N VG
Sbjct: 4601 KFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRS 4660
Query: 222 QCLLRLNV----VPPS 233
C R+NV +PPS
Sbjct: 4661 SCKARINVLDLIIPPS 4676
Score = 38.5 bits (88), Expect = 0.010
Identities = 33/147 (22%), Positives = 66/147 (44%), Gaps = 11/147 (7%)
Query: 99 KSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDF 158
K+ SI++ N+ SDIG Y CK + G ++ + V L +P ++ + +
Sbjct: 5568 KNFHTSIHILNVDTSDIGEYHCKAQNEVG-SDTCVCTVKLKEPPRFVSKLNSLTVVAGEP 5626
Query: 159 KIKCEPKEGSLPLQYEWQK-----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCT 213
EG+ P+ +W K + +S+ + +++ + + + A +G Y C
Sbjct: 5627 AELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENV--ATLQFAKAEPANAGKYICQ 5684
Query: 214 VRNRVGSDQCLLRLNVVPPS---NKAG 237
++N G + + L V+ P+ KAG
Sbjct: 5685 IKNDGGMRENMATLMVLEPAVIVEKAG 5711
Score = 38.1 bits (87), Expect = 0.012
Identities = 31/138 (22%), Positives = 53/138 (38%), Gaps = 17/138 (12%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV--------LVKPSGARCYVDGSEEI 154
+S+ + Q+ D G Y CK G + L V L +P +V
Sbjct: 3511 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFV------ 3564
Query: 155 GSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS--VISVKNASSEYSGTYSC 212
G K C G+ ++ WQK + +W + ++ + N + + G YSC
Sbjct: 3565 GKAAKFICTVT-GTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSC 3623
Query: 213 TVRNRVGSDQCLLRLNVV 230
N+ G+D C L ++
Sbjct: 3624 KASNKFGADICQAELIII 3641
Score = 37.0 bits (84), Expect = 0.028
Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 17/158 (10%)
Query: 99 KSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCY------VDGSE 152
K+ + V ++D G Y CKV G A +V+ +P + V SE
Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSA-LCTSSIVIKEPKKPPVFDQHLTPVTVSE 8359
Query: 153 EIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMP--TSWLAEMTSSVISVKNASSEYSGTY 210
G ++ C +GS P++ +W K K S+ ++V+ +++ + SG Y
Sbjct: 8360 --GEYVQLSCH-VQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDY 8416
Query: 211 SCTVRNRVGSDQCLLRLNV-----VPPSNKAGLIAGAI 243
C N GSD ++ + V P+ K + G +
Sbjct: 8417 VCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRL 8454
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/135 (24%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A + ++ L+ +D GTY C G HL V P S+++ + +++
Sbjct: 4730 AFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVE--KPQSQDVNPNTRVQL 4787
Query: 163 EPKEG-SLPLQYEWQKLSDSQKMPT----SWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
+ G + P+ +W K D++++ + S + TS+ + + A + SGTY C + N
Sbjct: 4788 KALVGGTAPMTIKWFK--DNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSND 4845
Query: 218 VGSDQCLLRLNVVPP 232
VG+ L V P
Sbjct: 4846 VGTATSKATLFVKEP 4860
Score = 36.2 bits (82), Expect = 0.047
Identities = 28/137 (20%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A + + + + D G Y C ++ A G + +++L P + +G ++C
Sbjct: 7923 AILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC 7982
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISV--KNASSEYSGTYSCTVRNRVGS 220
+ G+ + W K + T++ ++V ++ SG Y C N VG
Sbjct: 7983 Q-LAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGE 8041
Query: 221 DQCLLRLNV----VPPS 233
L V +PPS
Sbjct: 8042 VSASTFLTVQEQKLPPS 8058
Score = 35.4 bits (80), Expect = 0.081
Identities = 30/141 (21%), Positives = 51/141 (36%), Gaps = 18/141 (12%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVL---------VKPSGARCYVDGSEE 153
A++ + LS G Y C G A+ L +KP +D
Sbjct: 6230 ATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVS----IDVIAG 6285
Query: 154 IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV--ISVKNASSEYSGTYS 211
+DF+ G+ P++ W K + + ++ + + + SG Y+
Sbjct: 6286 ESADFECHVT---GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYT 6342
Query: 212 CTVRNRVGSDQCLLRLNVVPP 232
C N VG D C +L+V P
Sbjct: 6343 CQATNDVGKDMCSAQLSVKEP 6363
Score = 34.7 bits (78), Expect = 0.14
Identities = 48/219 (21%), Positives = 72/219 (32%), Gaps = 37/219 (16%)
Query: 23 TTPEEMIEKAK------GETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSG 76
T P K K G + + CK SP P+ + W + G
Sbjct: 7679 TVPPSFTRKLKETNGLSGSSVVMECKVYGSP----PISVSWF---------------HEG 7719
Query: 77 DKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLV 136
++I GR + T+ L ++ V L+ SD G Y C G L
Sbjct: 7720 NEISS-------GRKYQTT--LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 7770
Query: 137 VLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV 196
V PS + G++ K G+ P W K S + SV
Sbjct: 7771 VREPPSFVQKPDPMDVLTGTNVTFTSIVK-GTPPFSVSWFKGSSELVPGDRCNVSLEDSV 7829
Query: 197 ISVK--NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPS 233
++ + + SG Y+C V N G C L + P+
Sbjct: 7830 AELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 7868
Score = 33.5 bits (75), Expect = 0.31
Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 7/134 (5%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCE 163
++ + +L SD+G Y C G + L V PS + + E +
Sbjct: 5856 TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVK-EPEPLEVLPGKNVTFTS 5914
Query: 164 PKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG 219
G+ P + W ++L + + E T + + + N SG Y+C V N G
Sbjct: 5915 VIRGTPPFKVNWFRGARELVKGDRCNIYF--EDTVAELELFNIDISQSGEYTCVVSNNAG 5972
Query: 220 SDQCLLRLNVVPPS 233
C RL V P+
Sbjct: 5973 QASCTTRLFVKEPA 5986
Score = 33.1 bits (74), Expect = 0.40
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 3/132 (2%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCE 163
++N++ L+ SD G Y C G L V PS + D E +
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT-PDSVEVLPGMSLTFTS 6855
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK--NASSEYSGTYSCTVRNRVGSD 221
G+ P + +W K S S + V ++ SG YSC V N GS
Sbjct: 6856 VIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSA 6915
Query: 222 QCLLRLNVVPPS 233
C L V P+
Sbjct: 6916 SCTTHLFVKEPA 6927
Score = 32.7 bits (73), Expect = 0.53
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 8/111 (7%)
Query: 123 KKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW----QKL 178
+K VA K+ + + SG + G E G K C+ + Q W ++L
Sbjct: 31552 QKGVSVAKVKVASIEIGPVSGQIMHAVGEE--GGHVKYVCKIENYDQSTQVTWYFGVRQL 31609
Query: 179 SDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV 229
+S+K ++ E +++ VK+ + GTY C V N G D L V
Sbjct: 31610 ENSEKYEITY--EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Score = 31.6 bits (70), Expect = 1.2
Identities = 27/123 (21%), Positives = 49/123 (39%), Gaps = 5/123 (4%)
Query: 103 ASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC 162
A + + + D G Y ++K G ++ I +++L KP + E + I
Sbjct: 29794 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 29853
Query: 163 EPKE--GSLPLQYEWQKLSDSQK---MPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
EP E G PL + D+ + +P S ++ + +EY + T R
Sbjct: 29854 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG 29913
Query: 218 VGS 220
+GS
Sbjct: 29914 IGS 29916
Score = 30.8 bits (68), Expect = 2.0
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 148 VDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYS 207
V E++ D K P + ++ + + Q L ++ ++ S +TS +S+K AS E
Sbjct: 25406 VKAREQLKIDVPFKGRP-QATVNWRKDGQTLKETTRVNVSSSKTVTS--LSIKEASKEDV 25462
Query: 208 GTYSCTVRNRVGS 220
GTY V N GS
Sbjct: 25463 GTYELCVSNSAGS 25475
Score = 30.8 bits (68), Expect = 2.0
Identities = 30/136 (22%), Positives = 55/136 (40%), Gaps = 4/136 (2%)
Query: 87 LKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARC 146
LK + F + ++ + + +IN+ +D G Y+ + G I++VVL +P
Sbjct: 26517 LKATMRFNT-EITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTG 26575
Query: 147 YVDGSEEIGSDFKIKCEPKE---GSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNAS 203
V S+ +K EP + GS Y K S + T A + +++ V +
Sbjct: 26576 PVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLT 26635
Query: 204 SEYSGTYSCTVRNRVG 219
+ + NR G
Sbjct: 26636 TGEEYQFRIKAENRFG 26651
Score = 30.0 bits (66), Expect = 3.4
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 175 WQKLSDSQKMPTSWLAEMT--SSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVV 230
W+K + + PT ++T S + ++NA+ E G YS TV N GS +++ V+
Sbjct: 17252 WKK--EDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVL 17307
Score = 30.0 bits (66), Expect = 3.4
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 194 SSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVV----PPSNKAGLI 239
SSV+++KN +G Y TV N GS + L V+ PP+ ++
Sbjct: 17565 SSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINIL 17614
Score = 29.6 bits (65), Expect = 4.4
Identities = 23/107 (21%), Positives = 42/107 (39%), Gaps = 9/107 (8%)
Query: 107 VTNLQLSDIGTYQCKVKKAPGVANKKIHLVV---LVKPSGARCYVDGSEEIGSDFKIKCE 163
+ N L D G Y C++ + K+H + + KP G + C
Sbjct: 12521 IQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILE------GEKAEFVCS 12574
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTY 210
+ S P+Q++ + +A+ V+ VK+A+ + GTY
Sbjct: 12575 ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621
Score = 28.9 bits (63), Expect = 7.6
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 174 EWQKLSDSQKMPTSWLA--EMTSSVISV--KNASSEYSGTYSCTVRNRVGSDQCLLRLNV 229
EW K D +++ T+ L E T+ + S+ K+A SG Y +RN +GS +R+ +
Sbjct: 26905 EWYK--DDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 26962
Query: 230 VPPSNKAG 237
+ G
Sbjct: 26963 LDKPGPPG 26970
Score = 28.5 bits (62), Expect = 9.9
Identities = 30/149 (20%), Positives = 59/149 (39%), Gaps = 21/149 (14%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGA----RCYVDGS---- 151
SG A + + ++ +D G Y CK G K + + KP+ A + VDG
Sbjct: 8398 SGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFV 8457
Query: 152 ---------EEIGSDF--KIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK 200
E+ + F K+ +P + +W++L+ ++ + + + ++
Sbjct: 8458 SEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGD--EAKLEIR 8515
Query: 201 NASSEYSGTYSCTVRNRVGSDQCLLRLNV 229
+ + SG Y C N G + + L V
Sbjct: 8516 DTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 28.5 bits (62), Expect = 9.9
Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 307 PSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIP---VMIPAQSKD 361
P ++E + +VP + P++PT P KV AP IP V +P Q K+
Sbjct: 10255 PPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKE 10312
Score = 28.5 bits (62), Expect = 9.9
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 11/142 (7%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDG--SEEI- 154
+ D ++ + D G C K G+ + L + + S A ++ S+ I
Sbjct: 33087 VSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNIN 33146
Query: 155 -GSDFKIKCEPKEGSLPLQYEWQK----LSDSQKMPTSWLAEMTSSVISVKNASSEYSGT 209
G + CE P + EW K +S S + S + S + ++NAS SG
Sbjct: 33147 EGQNVLFTCEISGEPSP-EIEWFKNNLPISISSNVSISRSRNVYS--LEIRNASVSDSGK 33203
Query: 210 YSCTVRNRVGSDQCLLRLNVVP 231
Y+ +N G L V+P
Sbjct: 33204 YTIKAKNFRGQCSATASLMVLP 33225
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/274 (20%), Positives = 112/274 (40%), Gaps = 35/274 (12%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKK-IHLVV--------LVKPSGARCYV 148
L + + ++ + LQ +D G Y C+V A + + L + + + S +
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
Query: 149 DGSEEIGSDFKIKC--EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEY 206
E+ S ++C E K G+ +Y W + E + ++ + E+
Sbjct: 362 TIEAELNSSLTLQCWAESKPGA---EYRWTLEHST--------GEHLGEQLIIRALTWEH 410
Query: 207 SGTYSCTVRNRVG--SDQCLLRLNVVPPSNKA---GLIAGAIIGTLLALAL---IGLIIF 258
G Y+CT N + + + + VV P + + G IAG +IG L +A+ +G ++
Sbjct: 411 DGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLY 470
Query: 259 CCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQY 318
+R K ++ H+ + +P + T + + + ++ S ++G + +
Sbjct: 471 IRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNI-----SQLQGRIRVEL 525
Query: 319 NQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIP 352
++PS SP PP K P L + +P
Sbjct: 526 TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVP 559
Score = 31.2 bits (69), Expect = 1.5
Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 28/150 (18%)
Query: 86 DLKGRVHFTSNDLK---------SGDASI-NVTNLQLSDIGTYQCKVKKA-PGVANKKIH 134
D+ +H+ SN+L S D I + +Q D GTYQC+ + A + I
Sbjct: 94 DVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
Query: 135 LVVLVKPSGARCYVD---GSEEI-----GSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPT 186
L V P ++ S E+ GS E K P Y W L
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHP-PCAYTWFLLDS------ 206
Query: 187 SWLAEMTSSVISVKNASSEYSGTYSCTVRN 216
+ T+ ++ S E+ G Y C V N
Sbjct: 207 --ILSHTTRTFTIHAVSREHEGLYRCLVSN 234
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 57.0 bits (136), Expect = 3e-08
Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 35/202 (17%)
Query: 29 IEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLK 88
+ +G A+LPCK SPE +I W DK D P
Sbjct: 2856 LSTTEGSHAFLPCKARGSPEP----NITW-------------------DK---DGQPVSG 2889
Query: 89 GRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYV 148
FT SG+ + V NL+ D GTY C + A G A +++HL +LV P
Sbjct: 2890 AEGKFTIQP--SGE--LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPG 2945
Query: 149 DGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT-SSVISVKNASSEYS 207
D S +G ++C + GS + W + + + T ++E S + S E S
Sbjct: 2946 DRSLRLGDRLWLRCAAR-GSPTPRIGW---TVNDRPVTEGVSEQDGGSTLQRAAVSREDS 3001
Query: 208 GTYSCTVRNRVGSDQCLLRLNV 229
GTY C NRVG Q + ++V
Sbjct: 3002 GTYVCWAENRVGRTQAVSFVHV 3023
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 1/126 (0%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + D G Y C K + G A K LVV V P D S GS + C+
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2870
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCL 224
+ GS W K S + VKN + +GTY+CT N VG +
Sbjct: 2871 R-GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 2929
Query: 225 LRLNVV 230
+ L ++
Sbjct: 2930 VHLTIL 2935
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDFKIKC 162
+ ++ LQ + GTY C + A K + VLV P V + G + ++ C
Sbjct: 1989 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 2048
Query: 163 EPKEGSLPLQYEWQKLSD--SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
E +G P W K Q M + + +K + +G Y+C N G
Sbjct: 2049 E-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 2107
Query: 221 DQCLLRLNV-VPPSNKAG 237
D L +NV VPP+ K G
Sbjct: 2108 DARLHTVNVLVPPTIKQG 2125
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/216 (24%), Positives = 78/216 (36%), Gaps = 41/216 (18%)
Query: 26 EEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYP 85
EE+I+ G+TA+L C T P+ + + W + D P
Sbjct: 1261 EEVIKVLDGQTAHLMCNVTGHPQPK----LTW----------------------FKDGRP 1294
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGAR 145
+G H S D + V LS G Y C A G K L VL+ P+
Sbjct: 1295 LARGDAHHISPD----GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 1350
Query: 146 CYVDGSEE-----IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV--IS 198
D ++E + + + CE P W K D S ++ +
Sbjct: 1351 GAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQ 1407
Query: 199 VKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPS 233
+ NA E +G Y+C V N +G + V +PPS
Sbjct: 1408 ILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1443
Score = 45.8 bits (107), Expect = 6e-05
Identities = 49/192 (25%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 69 QVIILYSGDKIYDDYY--PDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAP 126
Q+ + GD + D ++ L R + L++G +I+ T + D G YQC +
Sbjct: 3046 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRT--ERDDAGRYQCLAENEM 3103
Query: 127 GVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW----QKLSDSQ 182
GVA K + LV+ P D + G D ++C+ P EW Q L S+
Sbjct: 3104 GVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP-TIEWLQAGQPLRASR 3162
Query: 183 KMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAG 241
++ T + + ++N + +GTY C N +GS L V P G + G
Sbjct: 3163 RLRT-----LPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTG 3217
Query: 242 AIIGTLLALALI 253
I G +A +
Sbjct: 3218 VINGRKFGVATL 3229
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP--SGARCYVDGSEEIGSDFKIK 161
++ ++ +QL+D G + C GVA++ L V V P D GS ++
Sbjct: 2177 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2236
Query: 162 CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSD 221
CE + LPL W K D + + + L + S + A SGTYSC + G
Sbjct: 2237 CEARGVPLPL-VSWMK--DGEPLLSQSLEQGPSLQLEAVGAGD--SGTYSCVAVSEAGEA 2291
Query: 222 QCLLRLNVVPP 232
+ +L V+ P
Sbjct: 2292 RRHFQLTVMEP 2302
Score = 42.4 bits (98), Expect = 7e-04
Identities = 68/300 (22%), Positives = 107/300 (35%), Gaps = 43/300 (14%)
Query: 82 DYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP 141
D P L G H ++ + +T + D G YQC G + L V P
Sbjct: 254 DRQPVLPGGPHL---QVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPP 310
Query: 142 SGARCYVDGSEEIGSDFKIK--CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS--VI 197
+ G + D ++ CE + P W K D +PTS T +
Sbjct: 311 TIWGSNETGEVAVMEDHLVQLLCEARGVPTP-NITWFK--DGALLPTSTKVVYTRGGRQL 367
Query: 198 SVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAG----LIAGAIIGTLLALAL 252
+ A S +G Y+C N VG+ + RL+V VPP+ + + A+ G +AL
Sbjct: 368 QLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 427
Query: 253 IGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYI-----GSNHSSLGSMSP 307
+ R HH+ +SR T S + G S L S
Sbjct: 428 VA---------RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA 478
Query: 308 SNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAI---PVMIPAQSKDGSI 364
S+ G + QY+ +PP + A L ++ I P+ +P Q+ +
Sbjct: 479 SSPAGEAVLQYS-----------VEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPV 527
Score = 42.0 bits (97), Expect = 9e-04
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 3/131 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI-GSDFKIKCE 163
+ V+ +++D +Y C + G A K L V V P A ++ I S + C+
Sbjct: 1710 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCD 1769
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W K S + + + + + A SG Y+C N G DQ
Sbjct: 1770 VHAHPNP-EVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1828
Query: 224 LLRLNV-VPPS 233
L++L+V VPP+
Sbjct: 1829 LVQLSVLVPPA 1839
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 13/145 (8%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS-------GARCYVDG 150
L G + + N Q D G Y C V G A K H+ VL+ PS G +
Sbjct: 1399 LLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEV 1458
Query: 151 SEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKM-PTSWLAEM-TSSVISVKNASSEYSG 208
++ S ++CE P W K D Q + P+S L + ++ ++ SG
Sbjct: 1459 KTKVNSTLTLECE-SWAVPPPTIRWYK--DGQPVTPSSRLQVLGEGRLLQIQPTQVSDSG 1515
Query: 209 TYSCTVRNRVG-SDQCLLRLNVVPP 232
Y C N G DQ L VPP
Sbjct: 1516 RYLCVATNVAGEDDQDFNVLIQVPP 1540
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 116 GTYQCKVKKAPGVANKKIHLVV----LVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPL 171
G Y C + + GVA+K + L V +VKP + EE+ + CE P
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEV----LLPCEASGIPRP- 2786
Query: 172 QYEWQKLSDSQKMPTSWLAE-MTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV- 229
WQK + + T + + + + +AS E +G Y C +N GS RL V
Sbjct: 2787 TITWQK--EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844
Query: 230 VPPSNKAGL 238
VPP + GL
Sbjct: 2845 VPPVIENGL 2853
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + L D G Y C G + +++ L VLV P+ V+ + + ++C
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC-L 717
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTS---SVISVKNASSEYSGTYSCTVRNRVGSD 221
G P W K + +SW+ S V+ ++ A +G+Y C N GS
Sbjct: 718 ASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST 774
Query: 222 QCL--LRLNVVP 231
+ LR+NV P
Sbjct: 775 ELRYGLRVNVPP 786
Score = 38.9 bits (89), Expect = 0.007
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSE----E 153
L G ++ + +LSD G Y C+ A G K + L VLV P+ + +
Sbjct: 1795 LLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVR 1854
Query: 154 IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV-----ISVKNASSEYSG 208
+G + CE P W K D Q + LA+ T ++ + ++ A G
Sbjct: 1855 VGDKAVLSCETDALPEP-TVTWYK--DGQPLV---LAQRTQALRGGQRLEIQEAQVSDKG 1908
Query: 209 TYSCTVRNRVGSDQCLLRLNV-VPPS 233
YSC V N G L V VPP+
Sbjct: 1909 LYSCKVSNVAGEAVRTFTLTVQVPPT 1934
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP---SGARCYVDGSEEI 154
L++ S++V Q + G Y C + G A +K L VLV P + + +
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 1175
Query: 155 GSDFKIKCEPKEGSLPLQYEW-------QKLSDSQKMPTSWLAEMTSSVISVKNASSEYS 207
S + CE G P W D+ + W+ +MT + + S
Sbjct: 1176 HSPLTLLCEAM-GIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQT-------QEQDS 1227
Query: 208 GTYSCTVRNRVGSDQCLLRLNV-VPPS 233
G YSC N G + + V VPPS
Sbjct: 1228 GLYSCLASNEAGEARRNFSVEVLVPPS 1254
Score = 37.7 bits (86), Expect = 0.016
Identities = 46/178 (25%), Positives = 67/178 (37%), Gaps = 20/178 (11%)
Query: 62 ADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
AD Q V L G + D P L+ + S LK L+ SD G Y C
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKG---------LRASDAGAYTC- 2099
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQK 177
V P + ++H V ++ P + DGS + G + C P GS P+ W
Sbjct: 2100 VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSW-- 2156
Query: 178 LSDSQKMPTS--WLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPP 232
L D +P S L + + + +G ++C + G L V VPP
Sbjct: 2157 LKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPP 2214
Score = 35.8 bits (81), Expect = 0.062
Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 6/119 (5%)
Query: 101 GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDG-SEEIGSDFK 159
G + + Q+SD G Y CKV G A + L V V P+ + S+ GS
Sbjct: 1893 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1952
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTS--SVISVKNASSEYSGTYSCTVRN 216
+ C+ P W L D + +S + + S + + +GTY+C N
Sbjct: 1953 LTCDVSGVPAP-TVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008
Score = 35.4 bits (80), Expect = 0.081
Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 8/145 (5%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP-SGARCYVDGSEEIGS 156
L + A + V + D G Y C+ G + K +L V V P R + G
Sbjct: 928 LSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGH 987
Query: 157 DFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVIS----VKNASSEYSGTYSC 212
+ CE + P + W+K D Q +P S + + A GTY+C
Sbjct: 988 PTSLSCECRGVPFP-KISWRK--DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 1044
Query: 213 TVRNRVGSDQCLLRLNVVPPSNKAG 237
N VG+ L+L V P AG
Sbjct: 1045 ECSNVVGNSSQDLQLEVHVPPQIAG 1069
Score = 35.0 bits (79), Expect = 0.11
Identities = 29/135 (21%), Positives = 50/135 (37%), Gaps = 14/135 (10%)
Query: 111 QLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKI--------KC 162
QL+ GTY C+ G +++ + L V V P + G E + + +C
Sbjct: 1035 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQ-----IAGPREPPTQVSVVQDGVATLEC 1089
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQ 222
G P W++ + + V+ A + ++G YSC N G +
Sbjct: 1090 NAT-GKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1148
Query: 223 CLLRLNVVPPSNKAG 237
L+V+ P G
Sbjct: 1149 RKFELSVLVPPELIG 1163
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Query: 102 DASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS----GARCYVDGSEEIGSD 157
+ S+ + ++ +D G Y+C+ G +++ LVV V PS G + V G G
Sbjct: 56 EGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGM--AGQS 113
Query: 158 FKIKCEPKEGSLPLQYEWQKLSDSQKMPTSW 188
++C+ +P + W K + +P W
Sbjct: 114 LTLECDANGFPVP-EIVWLKDAQLVGVPLGW 143
Score = 33.9 bits (76), Expect = 0.24
Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 15/147 (10%)
Query: 95 SNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP----SGARCYVDG 150
S L+ G S+ + + D GTY C G A + L V+ P SG +
Sbjct: 2258 SQSLEQGP-SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTEL-- 2314
Query: 151 SEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTY 210
S G+ ++ C+ +G+ W K D Q + + V+ V++A G Y
Sbjct: 2315 SLTPGAPMELLCDA-QGTPQPNITWHK--DGQALTRLENNSRATRVLRVRDA-----GLY 2366
Query: 211 SCTVRNRVGSDQCLLRLNVVPPSNKAG 237
+C + G+ + R+ V P N G
Sbjct: 2367 TCLAESPAGAIEKSFRVRVQAPPNIVG 2393
Score = 33.5 bits (75), Expect = 0.31
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS-GARCYVDGSEEIGSDFKIKCE 163
+ + QLSD G+Y+C G + L V V P + G + + ++ C
Sbjct: 750 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 809
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS-VISVKNASSEYSGTYSCTVRNRVGSDQ 222
P + + T L V+++ +A + SG YSC + VG D+
Sbjct: 810 ATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 869
Query: 223 CLLRLNV-VPPS 233
+ L V +PPS
Sbjct: 870 QDVVLQVHMPPS 881
Score = 33.5 bits (75), Expect = 0.31
Identities = 53/238 (22%), Positives = 77/238 (32%), Gaps = 43/238 (18%)
Query: 13 VVDFARSLSITTPEEMI--------EKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADN 64
V DF+ + I + EE E + AYL C P P D+ W
Sbjct: 1545 VGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIP----PPDLTWYREDQPL 1600
Query: 65 QKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKK 124
D+V +L G RV + + ++ + G Y CK
Sbjct: 1601 SAGDEVSVLQGG-------------RV-------------LQIPLVRAENAGRYSCKASN 1634
Query: 125 APGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQKLSD 180
G L+VL P + EE+ S ++C +P Q
Sbjct: 1635 EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLP 1694
Query: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
P + E V+ V A + +Y C N+ GS + L L V P AGL
Sbjct: 1695 FSPSPRLQVLE-DGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGL 1751
Score = 32.7 bits (73), Expect = 0.53
Identities = 28/126 (22%), Positives = 47/126 (37%), Gaps = 11/126 (8%)
Query: 110 LQLSDIGTYQCKVKKAPGVANKKIHLVV-----LVKPSGARCYVD-GSEEIGSDFKIKCE 163
L++ D G Y C + G K + V +V P G R V ++ + ++ E
Sbjct: 2358 LRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAE 2417
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W + + + ++ S+ SG YSCT RN GS
Sbjct: 2418 PAP-----KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 2472
Query: 224 LLRLNV 229
R+ +
Sbjct: 2473 AFRVEI 2478
Score = 30.4 bits (67), Expect = 2.6
Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 1/106 (0%)
Query: 114 DIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQY 173
D ++C V G A++ + V V P+ A D + + + + C P
Sbjct: 2639 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPT-V 2697
Query: 174 EWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG 219
W K S S + + A ++G Y+C+ RN G
Sbjct: 2698 SWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2743
Score = 28.9 bits (63), Expect = 7.6
Identities = 35/162 (21%), Positives = 60/162 (37%), Gaps = 20/162 (12%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV--------LVKPSGARCYVDGS 151
S ++++ +++L G + C+ G A ++ + V L P G Y G
Sbjct: 549 SQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ--YHWGX 606
Query: 152 EEIGSDFKIKCEPK-------EGSLPLQYEWQKLSDSQKMPTSW-LAEMTSSVISVKNAS 203
E S F C+P PL W PT +A + ++
Sbjct: 607 EH-HSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVD 665
Query: 204 SEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAGAII 244
G Y+C N G + + L V VPP+ + G + A++
Sbjct: 666 LRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL 707
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 57.0 bits (136), Expect = 3e-08
Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 35/202 (17%)
Query: 29 IEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLK 88
+ +G A+LPCK SPE +I W DK D P
Sbjct: 4047 LSTTEGSHAFLPCKARGSPEP----NITW-------------------DK---DGQPVSG 4080
Query: 89 GRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYV 148
FT SG+ + V NL+ D GTY C + A G A +++HL +LV P
Sbjct: 4081 AEGKFTIQP--SGE--LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPG 4136
Query: 149 DGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT-SSVISVKNASSEYS 207
D S +G ++C + GS + W + + + T ++E S + S E S
Sbjct: 4137 DRSLRLGDRLWLRCAAR-GSPTPRIGW---TVNDRPVTEGVSEQDGGSTLQRAAVSREDS 4192
Query: 208 GTYSCTVRNRVGSDQCLLRLNV 229
GTY C NRVG Q + ++V
Sbjct: 4193 GTYVCWAENRVGRTQAVSFVHV 4214
Score = 48.9 bits (115), Expect = 7e-06
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 40/224 (17%)
Query: 25 PEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWL----ISPADNQKVDQVIILYSGDKIY 80
P + + GETA L C+ + P ++ W+ + PA +V Q+
Sbjct: 522 PAPNVTVSPGETAVLSCRVL----GEAPYNLTWVRDWRVLPASTGRVAQL---------- 567
Query: 81 DDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVK 140
D S+ ++ + +D G YQC A GV + L+V
Sbjct: 568 --------------------ADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREA 607
Query: 141 PSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK 200
P + G + K+ C P W + S + + + + ++I ++
Sbjct: 608 PQVSIHTSSQHFSQGVEVKVSCSASGYPTP-HISWSRESQALQEDSRIHVDAQGTLI-IQ 665
Query: 201 NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAII 244
+ E +G YSC N VG+DQ + L P + + + A ++
Sbjct: 666 GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV 709
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 1/126 (0%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + D G Y C K + G A K LVV V P D S GS + C+
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCL 224
+ GS W K S + VKN + +GTY+CT N VG +
Sbjct: 4062 R-GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 4120
Query: 225 LRLNVV 230
+ L ++
Sbjct: 4121 VHLTIL 4126
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 5/134 (3%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEE--IGSDFKIK 161
S++ ++ SD G Y+C+ + GV ++ L VL P G E G + +
Sbjct: 1168 SVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLP 1227
Query: 162 CEPKEGSLPLQYEWQKLSDSQKM-PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
C P G+ Q W+K S+ + +A + + + + S SG Y C N VGS
Sbjct: 1228 C-PARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 1286
Query: 221 DQCLLRLNV-VPPS 233
+L V VPPS
Sbjct: 1287 TSRRAKLVVYVPPS 1300
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDFKIKC 162
+ ++ LQ + GTY C + A K + VLV P V + G + ++ C
Sbjct: 3180 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239
Query: 163 EPKEGSLPLQYEWQKLSD--SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
E +G P W K Q M + + +K + +G Y+C N G
Sbjct: 3240 E-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 3298
Query: 221 DQCLLRLNV-VPPSNKAG 237
D L +NV VPP+ K G
Sbjct: 3299 DARLHTVNVLVPPTIKQG 3316
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/216 (24%), Positives = 78/216 (36%), Gaps = 41/216 (18%)
Query: 26 EEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYP 85
EE+I+ G+TA+L C T P+ + + W + D P
Sbjct: 2452 EEVIKVLDGQTAHLMCNVTGHPQPK----LTW----------------------FKDGRP 2485
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGAR 145
+G H S D + V LS G Y C A G K L VL+ P+
Sbjct: 2486 LARGDAHHISPD----GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 2541
Query: 146 CYVDGSEE-----IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV--IS 198
D ++E + + + CE P W K D S ++ +
Sbjct: 2542 GAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQ 2598
Query: 199 VKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPS 233
+ NA E +G Y+C V N +G + V +PPS
Sbjct: 2599 ILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 2634
Score = 45.8 bits (107), Expect = 6e-05
Identities = 49/192 (25%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 69 QVIILYSGDKIYDDYY--PDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAP 126
Q+ + GD + D ++ L R + L++G +I+ T + D G YQC +
Sbjct: 4237 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRT--ERDDAGRYQCLAENEM 4294
Query: 127 GVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEW----QKLSDSQ 182
GVA K + LV+ P D + G D ++C+ P EW Q L S+
Sbjct: 4295 GVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP-TIEWLQAGQPLRASR 4353
Query: 183 KMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAG 241
++ T + + ++N + +GTY C N +GS L V P G + G
Sbjct: 4354 RLRT-----LPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTG 4408
Query: 242 AIIGTLLALALI 253
I G +A +
Sbjct: 4409 VINGRKFGVATL 4420
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP--SGARCYVDGSEEIGSDFKIK 161
++ ++ +QL+D G + C GVA++ L V V P D GS ++
Sbjct: 3368 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 3427
Query: 162 CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSD 221
CE + LPL W K D + + + L + S + A SGTYSC + G
Sbjct: 3428 CEARGVPLPL-VSWMK--DGEPLLSQSLEQGPSLQLEAVGAGD--SGTYSCVAVSEAGEA 3482
Query: 222 QCLLRLNVVPP 232
+ +L V+ P
Sbjct: 3483 RRHFQLTVMEP 3493
Score = 43.1 bits (100), Expect = 4e-04
Identities = 53/236 (22%), Positives = 88/236 (37%), Gaps = 57/236 (24%)
Query: 28 MIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQ--VIILYSGDKIYDDYYP 85
++E+ GE A LPC +P+ Q + W P+ Q V +L G
Sbjct: 1215 LLERVAGENASLPCPARGTPKPQ----VTWRKGPSSEPLHGQPGVAVLEEG--------- 1261
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS--- 142
S+ + ++ +D G Y+C+ G +++ LVV V PS
Sbjct: 1262 ------------------SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIRE 1303
Query: 143 -GARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWL--------AEMT 193
G + V G G ++C+ +P + W K + +P W ++
Sbjct: 1304 DGRKANVSGM--AGQSLTLECDANGFPVP-EIVWLKDAQLVGVPLGWAGYGWDLGWGQVG 1360
Query: 194 SSVISVKNASSEY-------SGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGA 242
+ + S + SG YSC N+ G+ Q L V+ P + G AGA
Sbjct: 1361 GHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLG--AGA 1414
Score = 42.7 bits (99), Expect = 5e-04
Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 15/148 (10%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS--GARCYVDGSEEIGSDFKIK 161
S++ +Q D G Y C+ + G A + HL+VL PS GA + G+D +++
Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 1429
Query: 162 CEPKEGSLPLQYEWQKLSDSQKM----PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
C P Q EW K D Q + P + E V+ + + G Y C +
Sbjct: 1430 CWTSGVPTP-QVEWTK--DRQPVLPGGPHLQVQE-DGQVLRITGSHVGDEGRYQCVAFSP 1485
Query: 218 VGSDQCLLRLNVVPP-----SNKAGLIA 240
G +L V P SN+ G +A
Sbjct: 1486 AGQQARDFQLRVHAPPTIWGSNETGEVA 1513
Score = 42.4 bits (98), Expect = 7e-04
Identities = 68/300 (22%), Positives = 107/300 (35%), Gaps = 43/300 (14%)
Query: 82 DYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP 141
D P L G H ++ + +T + D G YQC G + L V P
Sbjct: 1445 DRQPVLPGGPHL---QVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPP 1501
Query: 142 SGARCYVDGSEEIGSDFKIK--CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS--VI 197
+ G + D ++ CE + P W K D +PTS T +
Sbjct: 1502 TIWGSNETGEVAVMEDHLVQLLCEARGVPTP-NITWFK--DGALLPTSTKVVYTRGGRQL 1558
Query: 198 SVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAG----LIAGAIIGTLLALAL 252
+ A S +G Y+C N VG+ + RL+V VPP+ + + A+ G +AL
Sbjct: 1559 QLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 1618
Query: 253 IGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYI-----GSNHSSLGSMSP 307
+ R HH+ +SR T S + G S L S
Sbjct: 1619 VA---------RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA 1669
Query: 308 SNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAI---PVMIPAQSKDGSI 364
S+ G + QY+ +PP + A L ++ I P+ +P Q+ +
Sbjct: 1670 SSPAGEAVLQYS-----------VEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPV 1718
Score = 42.0 bits (97), Expect = 9e-04
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 3/131 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI-GSDFKIKCE 163
+ V+ +++D +Y C + G A K L V V P A ++ I S + C+
Sbjct: 2901 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCD 2960
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W K S + + + + + A SG Y+C N G DQ
Sbjct: 2961 VHAHPNP-EVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 3019
Query: 224 LLRLNV-VPPS 233
L++L+V VPP+
Sbjct: 3020 LVQLSVLVPPA 3030
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/145 (28%), Positives = 57/145 (39%), Gaps = 13/145 (8%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS-------GARCYVDG 150
L G + + N Q D G Y C V G A K H+ VL+ PS G +
Sbjct: 2590 LLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEV 2649
Query: 151 SEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKM-PTSWLAEM-TSSVISVKNASSEYSG 208
++ S ++CE P W K D Q + P+S L + ++ ++ SG
Sbjct: 2650 KTKVNSTLTLECE-SWAVPPPTIRWYK--DGQPVTPSSRLQVLGEGRLLQIQPTQVSDSG 2706
Query: 209 TYSCTVRNRVG-SDQCLLRLNVVPP 232
Y C N G DQ L VPP
Sbjct: 2707 RYLCVATNVAGEDDQDFNVLIQVPP 2731
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 116 GTYQCKVKKAPGVANKKIHLVV----LVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPL 171
G Y C + + GVA+K + L V +VKP + EE+ + CE P
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEV----LLPCEASGIPRP- 3977
Query: 172 QYEWQKLSDSQKMPTSWLAE-MTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV- 229
WQK + + T + + + + +AS E +G Y C +N GS RL V
Sbjct: 3978 TITWQK--EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035
Query: 230 VPPSNKAGL 238
VPP + GL
Sbjct: 4036 VPPVIENGL 4044
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + L D G Y C G + +++ L VLV P+ V+ + + ++C
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC-L 1908
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTS---SVISVKNASSEYSGTYSCTVRNRVGSD 221
G P W K + +SW+ S V+ ++ A +G+Y C N GS
Sbjct: 1909 ASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST 1965
Query: 222 QCL--LRLNVVP 231
+ LR+NV P
Sbjct: 1966 ELRYGLRVNVPP 1977
Score = 38.9 bits (89), Expect = 0.007
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSE----E 153
L G ++ + +LSD G Y C+ A G K + L VLV P+ + +
Sbjct: 2986 LLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVR 3045
Query: 154 IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV-----ISVKNASSEYSG 208
+G + CE P W K D Q + LA+ T ++ + ++ A G
Sbjct: 3046 VGDKAVLSCETDALPEP-TVTWYK--DGQPLV---LAQRTQALRGGQRLEIQEAQVSDKG 3099
Query: 209 TYSCTVRNRVGSDQCLLRLNV-VPPS 233
YSC V N G L V VPP+
Sbjct: 3100 LYSCKVSNVAGEAVRTFTLTVQVPPT 3125
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP---SGARCYVDGSEEI 154
L++ S++V Q + G Y C + G A +K L VLV P + + +
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 2366
Query: 155 GSDFKIKCEPKEGSLPLQYEW-------QKLSDSQKMPTSWLAEMTSSVISVKNASSEYS 207
S + CE G P W D+ + W+ +MT + + S
Sbjct: 2367 HSPLTLLCEAM-GIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQT-------QEQDS 2418
Query: 208 GTYSCTVRNRVGSDQCLLRLNV-VPPS 233
G YSC N G + + V VPPS
Sbjct: 2419 GLYSCLASNEAGEARRNFSVEVLVPPS 2445
Score = 37.7 bits (86), Expect = 0.016
Identities = 46/178 (25%), Positives = 67/178 (37%), Gaps = 20/178 (11%)
Query: 62 ADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
AD Q V L G + D P L+ + S LK L+ SD G Y C
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKG---------LRASDAGAYTC- 3290
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQK 177
V P + ++H V ++ P + DGS + G + C P GS P+ W
Sbjct: 3291 VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSW-- 3347
Query: 178 LSDSQKMPTS--WLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPP 232
L D +P S L + + + +G ++C + G L V VPP
Sbjct: 3348 LKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPP 3405
Score = 37.0 bits (84), Expect = 0.028
Identities = 35/137 (25%), Positives = 51/137 (37%), Gaps = 9/137 (6%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFK 159
S + + Q D GTY C+ G A+ +I L V P D + E+G
Sbjct: 745 SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSAL 804
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPT-------SWLAEMTSSVISVKNASSEYSGTYSC 212
+ C G P W++ D Q + S + S V+ ++ + E Y C
Sbjct: 805 LACR-ATGRPPPTVTWRR-GDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVC 862
Query: 213 TVRNRVGSDQCLLRLNV 229
RN G Q RL V
Sbjct: 863 EARNVFGKVQAEARLIV 879
Score = 35.8 bits (81), Expect = 0.062
Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 6/119 (5%)
Query: 101 GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDG-SEEIGSDFK 159
G + + Q+SD G Y CKV G A + L V V P+ + S+ GS
Sbjct: 3084 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 3143
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTS--SVISVKNASSEYSGTYSCTVRN 216
+ C+ P W L D + +S + + S + + +GTY+C N
Sbjct: 3144 LTCDVSGVPAP-TVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199
Score = 35.4 bits (80), Expect = 0.081
Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 8/145 (5%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP-SGARCYVDGSEEIGS 156
L + A + V + D G Y C+ G + K +L V V P R + G
Sbjct: 2119 LSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGH 2178
Query: 157 DFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVIS----VKNASSEYSGTYSC 212
+ CE + P + W+K D Q +P S + + A GTY+C
Sbjct: 2179 PTSLSCECRGVPFP-KISWRK--DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 2235
Query: 213 TVRNRVGSDQCLLRLNVVPPSNKAG 237
N VG+ L+L V P AG
Sbjct: 2236 ECSNVVGNSSQDLQLEVHVPPQIAG 2260
Score = 35.0 bits (79), Expect = 0.11
Identities = 29/135 (21%), Positives = 50/135 (37%), Gaps = 14/135 (10%)
Query: 111 QLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKI--------KC 162
QL+ GTY C+ G +++ + L V V P + G E + + +C
Sbjct: 2226 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQ-----IAGPREPPTQVSVVQDGVATLEC 2280
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQ 222
G P W++ + + V+ A + ++G YSC N G +
Sbjct: 2281 NAT-GKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 2339
Query: 223 CLLRLNVVPPSNKAG 237
L+V+ P G
Sbjct: 2340 RKFELSVLVPPELIG 2354
Score = 33.9 bits (76), Expect = 0.24
Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 15/147 (10%)
Query: 95 SNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP----SGARCYVDG 150
S L+ G S+ + + D GTY C G A + L V+ P SG +
Sbjct: 3449 SQSLEQGP-SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTEL-- 3505
Query: 151 SEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTY 210
S G+ ++ C+ +G+ W K D Q + + V+ V++A G Y
Sbjct: 3506 SLTPGAPMELLCDA-QGTPQPNITWHK--DGQALTRLENNSRATRVLRVRDA-----GLY 3557
Query: 211 SCTVRNRVGSDQCLLRLNVVPPSNKAG 237
+C + G+ + R+ V P N G
Sbjct: 3558 TCLAESPAGAIEKSFRVRVQAPPNIVG 3584
Score = 33.5 bits (75), Expect = 0.31
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS-GARCYVDGSEEIGSDFKIKCE 163
+ + QLSD G+Y+C G + L V V P + G + + ++ C
Sbjct: 1941 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 2000
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS-VISVKNASSEYSGTYSCTVRNRVGSDQ 222
P + + T L V+++ +A + SG YSC + VG D+
Sbjct: 2001 ATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 2060
Query: 223 CLLRLNV-VPPS 233
+ L V +PPS
Sbjct: 2061 QDVVLQVHMPPS 2072
Score = 33.5 bits (75), Expect = 0.31
Identities = 53/238 (22%), Positives = 77/238 (32%), Gaps = 43/238 (18%)
Query: 13 VVDFARSLSITTPEEMI--------EKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADN 64
V DF+ + I + EE E + AYL C P P D+ W
Sbjct: 2736 VGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIP----PPDLTWYREDQPL 2791
Query: 65 QKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKK 124
D+V +L G RV + + ++ + G Y CK
Sbjct: 2792 SAGDEVSVLQGG-------------RV-------------LQIPLVRAENAGRYSCKASN 2825
Query: 125 APGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQKLSD 180
G L+VL P + EE+ S ++C +P Q
Sbjct: 2826 EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLP 2885
Query: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
P + E V+ V A + +Y C N+ GS + L L V P AGL
Sbjct: 2886 FSPSPRLQVLE-DGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGL 2942
Score = 33.1 bits (74), Expect = 0.40
Identities = 29/131 (22%), Positives = 48/131 (36%), Gaps = 7/131 (5%)
Query: 102 DASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI---GSDF 158
D S+++ G Y C G ++ + LVV V P R + + I G
Sbjct: 937 DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPP---RIHPTATHHITNEGVPA 993
Query: 159 KIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRV 218
+ C P W K +++ + + S++ +G Y CT N V
Sbjct: 994 SLPCVASGVPAPT-ITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTV 1052
Query: 219 GSDQCLLRLNV 229
G +RL+V
Sbjct: 1053 GFSSQEMRLSV 1063
Score = 32.7 bits (73), Expect = 0.53
Identities = 28/126 (22%), Positives = 47/126 (37%), Gaps = 11/126 (8%)
Query: 110 LQLSDIGTYQCKVKKAPGVANKKIHLVV-----LVKPSGARCYVD-GSEEIGSDFKIKCE 163
L++ D G Y C + G K + V +V P G R V ++ + ++ E
Sbjct: 3549 LRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAE 3608
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W + + + ++ S+ SG YSCT RN GS
Sbjct: 3609 PAP-----KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 3663
Query: 224 LLRLNV 229
R+ +
Sbjct: 3664 AFRVEI 3669
Score = 32.0 bits (71), Expect = 0.90
Identities = 26/123 (21%), Positives = 45/123 (36%), Gaps = 5/123 (4%)
Query: 99 KSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDF 158
+SG++S + ++ GTY+C G K +VV P + + G
Sbjct: 475 ESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETA 534
Query: 159 KIKCEPKEGSLPLQYEWQKLSDSQKMP--TSWLAEMTSSVISVKNASSEYSGTYSCTVRN 216
+ C G P W + D + +P T +A++ + + G Y C N
Sbjct: 535 VLSCRVL-GEAPYNLTW--VRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN 591
Query: 217 RVG 219
G
Sbjct: 592 ANG 594
Score = 30.4 bits (67), Expect = 2.6
Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 1/106 (0%)
Query: 114 DIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQY 173
D ++C V G A++ + V V P+ A D + + + + C P
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPT-V 3888
Query: 174 EWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG 219
W K S S + + A ++G Y+C+ RN G
Sbjct: 3889 SWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 3934
Score = 28.9 bits (63), Expect = 7.6
Identities = 35/162 (21%), Positives = 60/162 (37%), Gaps = 20/162 (12%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV--------LVKPSGARCYVDGS 151
S ++++ +++L G + C+ G A ++ + V L P G Y G
Sbjct: 1740 SQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ--YHWGX 1797
Query: 152 EEIGSDFKIKCEPK-------EGSLPLQYEWQKLSDSQKMPTSW-LAEMTSSVISVKNAS 203
E S F C+P PL W PT +A + ++
Sbjct: 1798 EH-HSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVD 1856
Query: 204 SEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAGAII 244
G Y+C N G + + L V VPP+ + G + A++
Sbjct: 1857 LRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL 1898
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 57.0 bits (136), Expect = 3e-08
Identities = 58/202 (28%), Positives = 84/202 (41%), Gaps = 35/202 (17%)
Query: 29 IEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLK 88
+ +G A+LPCK SPE +I W DK D P
Sbjct: 2765 LSTTEGSHAFLPCKARGSPEP----NITW-------------------DK---DGQPVSG 2798
Query: 89 GRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYV 148
FT SG+ + V NL+ D GTY C + A G A +++HL +LV P
Sbjct: 2799 AEGKFTIQP--SGE--LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPG 2854
Query: 149 DGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMT-SSVISVKNASSEYS 207
D S +G ++C + GS + W + + + T ++E S + S E S
Sbjct: 2855 DRSLRLGDRLWLRCAAR-GSPTPRIGW---TVNDRPVTEGVSEQDGGSTLQRAAVSREDS 2910
Query: 208 GTYSCTVRNRVGSDQCLLRLNV 229
GTY C NRVG Q + ++V
Sbjct: 2911 GTYVCWAENRVGRTQAVSFVHV 2932
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 1/126 (0%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + D G Y C K + G A K LVV V P D S GS + C+
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2779
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCL 224
+ GS W K S + VKN + +GTY+CT N VG +
Sbjct: 2780 R-GSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRR 2838
Query: 225 LRLNVV 230
+ L ++
Sbjct: 2839 VHLTIL 2844
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 6/138 (4%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI--GSDFKIKC 162
+ ++ LQ + GTY C + A K + VLV P V + G + ++ C
Sbjct: 1898 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 1957
Query: 163 EPKEGSLPLQYEWQKLSD--SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGS 220
E +G P W K Q M + + +K + +G Y+C N G
Sbjct: 1958 E-ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGE 2016
Query: 221 DQCLLRLNV-VPPSNKAG 237
D L +NV VPP+ K G
Sbjct: 2017 DARLHTVNVLVPPTIKQG 2034
Score = 45.8 bits (107), Expect = 6e-05
Identities = 52/216 (24%), Positives = 78/216 (36%), Gaps = 41/216 (18%)
Query: 26 EEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYP 85
EE+I+ G+TA+L C T P+ + + W + D P
Sbjct: 1170 EEVIKVLDGQTAHLMCNVTGHPQPK----LTW----------------------FKDGRP 1203
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGAR 145
+G H S D + V LS G Y C A G K L VL+ P+
Sbjct: 1204 LARGDAHHISPD----GVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILG 1259
Query: 146 CYVDGSEE-----IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV--IS 198
D ++E + + + CE P W K D S ++ +
Sbjct: 1260 GAEDSADEEVTVTVNNPISLICEALAFPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQ 1316
Query: 199 VKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPS 233
+ NA E +G Y+C V N +G + V +PPS
Sbjct: 1317 ILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1352
Score = 45.8 bits (107), Expect = 6e-05
Identities = 40/157 (25%), Positives = 64/157 (40%), Gaps = 11/157 (7%)
Query: 102 DASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIK 161
+ S+ + + D G YQC + GVA K + LV+ P D + G D ++
Sbjct: 2988 NGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALR 3047
Query: 162 CEPKEGSLPLQYEW----QKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
C+ P EW Q L S+++ T + + ++N + +GTY C N
Sbjct: 3048 CQATGEPTP-TIEWLQAGQPLRASRRLRT-----LPDGSLWLENVETGDAGTYDCVAHNL 3101
Query: 218 VGSDQCLLRLNV-VPPSNKAGLIAGAIIGTLLALALI 253
+GS L V P G + G I G +A +
Sbjct: 3102 LGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATL 3138
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP--SGARCYVDGSEEIGSDFKIK 161
++ ++ +QL+D G + C GVA++ L V V P D GS ++
Sbjct: 2086 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2145
Query: 162 CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSD 221
CE + LPL W K D + + + L + S + A SGTYSC + G
Sbjct: 2146 CEARGVPLPL-VSWMK--DGEPLLSQSLEQGPSLQLEAVGAGD--SGTYSCVAVSEAGEA 2200
Query: 222 QCLLRLNVVPP 232
+ +L V+ P
Sbjct: 2201 RRHFQLTVMEP 2211
Score = 42.7 bits (99), Expect = 5e-04
Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 15/148 (10%)
Query: 104 SINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS--GARCYVDGSEEIGSDFKIK 161
S++ +Q D G Y C+ + G A + HL+VL PS GA + G+D +++
Sbjct: 88 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQ 147
Query: 162 CEPKEGSLPLQYEWQKLSDSQKM----PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNR 217
C P Q EW K D Q + P + E V+ + + G Y C +
Sbjct: 148 CWTSGVPTP-QVEWTK--DRQPVLPGGPHLQVQE-DGQVLRITGSHVGDEGRYQCVAFSP 203
Query: 218 VGSDQCLLRLNVVPP-----SNKAGLIA 240
G +L V P SN+ G +A
Sbjct: 204 AGQQARDFQLRVHAPPTIWGSNETGEVA 231
Score = 42.4 bits (98), Expect = 7e-04
Identities = 68/300 (22%), Positives = 107/300 (35%), Gaps = 43/300 (14%)
Query: 82 DYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP 141
D P L G H ++ + +T + D G YQC G + L V P
Sbjct: 163 DRQPVLPGGPHL---QVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPP 219
Query: 142 SGARCYVDGSEEIGSDFKIK--CEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS--VI 197
+ G + D ++ CE + P W K D +PTS T +
Sbjct: 220 TIWGSNETGEVAVMEDHLVQLLCEARGVPTP-NITWFK--DGALLPTSTKVVYTRGGRQL 276
Query: 198 SVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAG----LIAGAIIGTLLALAL 252
+ A S +G Y+C N VG+ + RL+V VPP+ + + A+ G +AL
Sbjct: 277 QLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 336
Query: 253 IGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYI-----GSNHSSLGSMSP 307
+ R HH+ +SR T S + G S L S
Sbjct: 337 VA---------RGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA 387
Query: 308 SNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAI---PVMIPAQSKDGSI 364
S+ G + QY+ +PP + A L ++ I P+ +P Q+ +
Sbjct: 388 SSPAGEAVLQYS-----------VEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPV 436
Score = 42.0 bits (97), Expect = 9e-04
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 3/131 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI-GSDFKIKCE 163
+ V+ +++D +Y C + G A K L V V P A ++ I S + C+
Sbjct: 1619 LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCD 1678
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W K S + + + + + A SG Y+C N G DQ
Sbjct: 1679 VHAHPNP-EVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1737
Query: 224 LLRLNV-VPPS 233
L++L+V VPP+
Sbjct: 1738 LVQLSVLVPPA 1748
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 116 GTYQCKVKKAPGVANKKIHLVV----LVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPL 171
G Y C + + GVA+K + L V +VKP + EE+ + CE P
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEV----LLPCEASGIPRP- 2695
Query: 172 QYEWQKLSDSQKMPTSWLAE-MTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV- 229
WQK + + T + + + + +AS E +G Y C +N GS RL V
Sbjct: 2696 TITWQK--EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2753
Query: 230 VPPSNKAGL 238
VPP + GL
Sbjct: 2754 VPPVIENGL 2762
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEP 164
+ + + L D G Y C G + +++ L VLV P+ V+ + + ++C
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLEC-L 626
Query: 165 KEGSLPLQYEWQKLSDSQKMPTSWLAEMTS---SVISVKNASSEYSGTYSCTVRNRVGSD 221
G P W K + +SW+ S V+ ++ A +G+Y C N GS
Sbjct: 627 ASGVPPPDVSWFK---GHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST 683
Query: 222 QCL--LRLNVVP 231
+ LR+NV P
Sbjct: 684 ELRYGLRVNVPP 695
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 17/147 (11%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIG-- 155
L G + + N Q D G Y C V G A K H+ VL+ PS ++ D E+G
Sbjct: 1308 LLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISK--DDPLAEVGVK 1365
Query: 156 -------SDFKIKCEPKEGSLPLQYEWQKLSDSQKM-PTSWLAEM-TSSVISVKNASSEY 206
S ++CE P W K D Q + P+S L + ++ ++
Sbjct: 1366 EVKTKVNSTLTLECE-SWAVPPPTIRWYK--DGQPVTPSSRLQVLGEGRLLQIQPTQVSD 1422
Query: 207 SGTYSCTVRNRVG-SDQCLLRLNVVPP 232
SG Y C N G DQ L VPP
Sbjct: 1423 SGRYLCVATNVAGEDDQDFNVLIQVPP 1449
Score = 38.9 bits (89), Expect = 0.007
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSE----E 153
L G ++ + +LSD G Y C+ A G K + L VLV P+ + +
Sbjct: 1704 LLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVR 1763
Query: 154 IGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSV-----ISVKNASSEYSG 208
+G + CE P W K D Q + LA+ T ++ + ++ A G
Sbjct: 1764 VGDKAVLSCETDALPEP-TVTWYK--DGQPLV---LAQRTQALRGGQRLEIQEAQVSDKG 1817
Query: 209 TYSCTVRNRVGSDQCLLRLNV-VPPS 233
YSC V N G L V VPP+
Sbjct: 1818 LYSCKVSNVAGEAVRTFTLTVQVPPT 1843
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/147 (25%), Positives = 56/147 (38%), Gaps = 19/147 (12%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP---SGARCYVDGSEEI 154
L++ S++V Q + G Y C + G A +K L VLV P + + +
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAAL 1084
Query: 155 GSDFKIKCEPKEGSLPLQYEW-------QKLSDSQKMPTSWLAEMTSSVISVKNASSEYS 207
S + CE G P W D+ + W+ +MT + + S
Sbjct: 1085 HSPLTLLCEAM-GIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQT-------QEQDS 1136
Query: 208 GTYSCTVRNRVGSDQCLLRLNV-VPPS 233
G YSC N G + + V VPPS
Sbjct: 1137 GLYSCLASNEAGEARRNFSVEVLVPPS 1163
Score = 37.7 bits (86), Expect = 0.016
Identities = 46/178 (25%), Positives = 67/178 (37%), Gaps = 20/178 (11%)
Query: 62 ADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
AD Q V L G + D P L+ + S LK L+ SD G Y C
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKG---------LRASDAGAYTC- 2008
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQK 177
V P + ++H V ++ P + DGS + G + C P GS P+ W
Sbjct: 2009 VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVC-PVRGSPPIHVSW-- 2065
Query: 178 LSDSQKMPTS--WLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNV-VPP 232
L D +P S L + + + +G ++C + G L V VPP
Sbjct: 2066 LKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPP 2123
Score = 36.2 bits (82), Expect = 0.047
Identities = 38/145 (26%), Positives = 56/145 (38%), Gaps = 8/145 (5%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP-SGARCYVDGSEEIGS 156
L + A + V + D G Y C+ G + K +L V V P R + G
Sbjct: 837 LSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGH 896
Query: 157 DFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVIS----VKNASSEYSGTYSC 212
++ CE + P + W+K D Q +P S + + A GTY+C
Sbjct: 897 PTRLSCECRGVPFP-KISWRK--DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 953
Query: 213 TVRNRVGSDQCLLRLNVVPPSNKAG 237
N VG+ L+L V P AG
Sbjct: 954 ECSNVVGNSSQDLQLEVHVPPQIAG 978
Score = 35.8 bits (81), Expect = 0.062
Identities = 30/119 (25%), Positives = 47/119 (39%), Gaps = 6/119 (5%)
Query: 101 GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDG-SEEIGSDFK 159
G + + Q+SD G Y CKV G A + L V V P+ + S+ GS
Sbjct: 1802 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1861
Query: 160 IKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTS--SVISVKNASSEYSGTYSCTVRN 216
+ C+ P W L D + +S + + S + + +GTY+C N
Sbjct: 1862 LTCDVSGVPAP-TVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917
Score = 35.0 bits (79), Expect = 0.11
Identities = 29/135 (21%), Positives = 50/135 (37%), Gaps = 14/135 (10%)
Query: 111 QLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKI--------KC 162
QL+ GTY C+ G +++ + L V V P + G E + + +C
Sbjct: 944 QLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQ-----IAGPREPPTQVSVVQDGVATLEC 998
Query: 163 EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQ 222
G P W++ + + V+ A + ++G YSC N G +
Sbjct: 999 NAT-GKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1057
Query: 223 CLLRLNVVPPSNKAG 237
L+V+ P G
Sbjct: 1058 RKFELSVLVPPELIG 1072
Score = 33.9 bits (76), Expect = 0.24
Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 15/147 (10%)
Query: 95 SNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKP----SGARCYVDG 150
S L+ G S+ + + D GTY C G A + L V+ P SG +
Sbjct: 2167 SQSLEQGP-SLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTEL-- 2223
Query: 151 SEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTY 210
S G+ ++ C+ +G+ W K D Q + + V+ V++A G Y
Sbjct: 2224 SLTPGAPMELLCDA-QGTPQPNITWHK--DGQALTRLENNSRATRVLRVRDA-----GLY 2275
Query: 211 SCTVRNRVGSDQCLLRLNVVPPSNKAG 237
+C + G+ + R+ V P N G
Sbjct: 2276 TCLAESPAGAIEKSFRVRVQAPPNIVG 2302
Score = 33.5 bits (75), Expect = 0.31
Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 3/132 (2%)
Query: 105 INVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPS-GARCYVDGSEEIGSDFKIKCE 163
+ + QLSD G+Y+C G + L V V P + G + + ++ C
Sbjct: 659 LRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCN 718
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS-VISVKNASSEYSGTYSCTVRNRVGSDQ 222
P + + T L V+++ +A + SG YSC + VG D+
Sbjct: 719 ATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 778
Query: 223 CLLRLNV-VPPS 233
+ L V +PPS
Sbjct: 779 QDVVLQVHMPPS 790
Score = 33.5 bits (75), Expect = 0.31
Identities = 53/238 (22%), Positives = 77/238 (32%), Gaps = 43/238 (18%)
Query: 13 VVDFARSLSITTPEEMI--------EKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADN 64
V DF+ + I + EE E + AYL C P P D+ W
Sbjct: 1454 VGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIP----PPDLTWYREDQPL 1509
Query: 65 QKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKK 124
D+V +L G RV + + ++ + G Y CK
Sbjct: 1510 SAGDEVSVLQGG-------------RV-------------LQIPLVRAENAGRYSCKASN 1543
Query: 125 APGVANKKIHLVVLVKPSGARCYVDGSEEI----GSDFKIKCEPKEGSLPLQYEWQKLSD 180
G L+VL P + EE+ S ++C +P Q
Sbjct: 1544 EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLP 1603
Query: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238
P + E V+ V A + +Y C N+ GS + L L V P AGL
Sbjct: 1604 FSPSPRLQVLE-DGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGL 1660
Score = 32.7 bits (73), Expect = 0.53
Identities = 28/126 (22%), Positives = 47/126 (37%), Gaps = 11/126 (8%)
Query: 110 LQLSDIGTYQCKVKKAPGVANKKIHLVV-----LVKPSGARCYVD-GSEEIGSDFKIKCE 163
L++ D G Y C + G K + V +V P G R V ++ + ++ E
Sbjct: 2267 LRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAE 2326
Query: 164 PKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQC 223
P + W + + + ++ S+ SG YSCT RN GS
Sbjct: 2327 PAP-----KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSV 2381
Query: 224 LLRLNV 229
R+ +
Sbjct: 2382 AFRVEI 2387
Score = 30.4 bits (67), Expect = 2.6
Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 1/106 (0%)
Query: 114 DIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQY 173
D ++C V G A++ + V V P+ A D + + + + C P
Sbjct: 2548 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPT-V 2606
Query: 174 EWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG 219
W K S S + + A ++G Y+C+ RN G
Sbjct: 2607 SWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2652
Score = 28.9 bits (63), Expect = 7.6
Identities = 35/162 (21%), Positives = 60/162 (37%), Gaps = 20/162 (12%)
Query: 100 SGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVV--------LVKPSGARCYVDGS 151
S ++++ +++L G + C+ G A ++ + V L P G Y G
Sbjct: 458 SQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ--YHWGX 515
Query: 152 EEIGSDFKIKCEPK-------EGSLPLQYEWQKLSDSQKMPTSW-LAEMTSSVISVKNAS 203
E S F C+P PL W PT +A + ++
Sbjct: 516 EH-HSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVD 574
Query: 204 SEYSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAGAII 244
G Y+C N G + + L V VPP+ + G + A++
Sbjct: 575 LRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL 616
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 55.1 bits (131), Expect = 1e-07
Identities = 51/210 (24%), Positives = 88/210 (41%), Gaps = 14/210 (6%)
Query: 156 SDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVR 215
+D + C+ + P Y+W S + PTS +A+ + VI S ++ T+ CTV
Sbjct: 277 TDATLSCDVRSNPEPTGYDWSTTSGT--FPTSAVAQGSQLVIHA--VDSLFNTTFVCTVT 332
Query: 216 NRVGSDQCLLRLNVVPPSNKAGL-----IAGAIIGTLLALALIGLIIFCCRKKRREEKYE 270
N VG + + V N AG I G II ++A A+ I CR++R+E+ +
Sbjct: 333 NAVGMGRAEQVIFVRETPNTAGAGATGGIIGGIIAAIIATAVAATGILICRQQRKEQTLQ 392
Query: 271 KEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTP 330
+ E P K T A+ S L ++ S ++ S + P
Sbjct: 393 GAEEDEDLEGPPSYKPPTPKAKLEAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMP 452
Query: 331 QSPTLPPAKVAA----PNLSRMGAIPVMIP 356
+ LP + + P + +G+ P+ +P
Sbjct: 453 RYHELPTLEERSGPLHPGATSLGS-PIPVP 481
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/269 (22%), Positives = 114/269 (42%), Gaps = 36/269 (13%)
Query: 25 PEEMIEKAKGETAYLPCKFTLSPEDQGP-LDIEWL---ISPADNQKVDQVIILYSGDKIY 80
P E I GE A LPC+ LSP L++ W +SPA V++ G +
Sbjct: 34 PPEPILAVVGEDAELPCR--LSPNASAEHLELRWFRKKVSPA-------VLVHRDGREQE 84
Query: 81 DDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVK 140
+ P+ +GR + + G ++ + +++SD G Y C ++ +HL V
Sbjct: 85 AEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAA- 143
Query: 141 PSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQ--------KLSDSQKMPTSWLAEM 192
G+ ++ + + ++C Q +W+ S+S+ L +
Sbjct: 144 -LGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTV 202
Query: 193 TSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVP---PSNKAGLIAGAIIGTLLA 249
+SVI +++ S++ SC ++N + + + +++ P ++A A+I +L
Sbjct: 203 AASVI-IRDTSAK---NVSCYIQNLLLGQEKKVEISIPASSLPRLTPWIVAVAVILMVLG 258
Query: 250 LALIGLIIFCCR------KKRREEKYEKE 272
L IG I F R ++RR E KE
Sbjct: 259 LLTIGSIFFTWRLYNERPRERRNEFSSKE 287
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 54.3 bits (129), Expect = 2e-07
Identities = 52/191 (27%), Positives = 76/191 (39%), Gaps = 20/191 (10%)
Query: 86 DLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKV---KKAPGVANKKIHLVVLVKPS 142
DL GR G S+ + N+ D Y+C+V + I L V VKP
Sbjct: 132 DLAGRAEIL------GKTSLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPV 185
Query: 143 GARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQK-----LSDSQKMP----TSWLAEMT 193
C V + +G + C+ EG Y W + +DS+ P +S+
Sbjct: 186 TPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSE 245
Query: 194 SSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALI 253
+ + + SG Y C N GS +C + V N G+I G ++ L LALI
Sbjct: 246 TGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDLNIGGIIGGVLV-VLAVLALI 304
Query: 254 GLIIFCCRKKR 264
L I CC +R
Sbjct: 305 TLGI-CCAYRR 314
>gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo
sapiens]
Length = 352
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/292 (21%), Positives = 127/292 (43%), Gaps = 32/292 (10%)
Query: 5 LCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKF--TLSPEDQGPLDIEWLISPA 62
+C +LL ++ + S+ P I GE A LPC T+S E ++++W+ S
Sbjct: 16 VCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAET---MELKWVSS-- 70
Query: 63 DNQKVDQVIILYS-GDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
+ QV+ +Y+ G ++ D +GR + + +G A++ + N+ SD G Y C
Sbjct: 71 ---SLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCY 127
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDS 181
+ + L V S V G ++ G ++C Q +W +
Sbjct: 128 FQDGDFYEKALVELKVAALGSDLHVDVKGYKDGG--IHLECRSTGWYPQPQIQWSN-NKG 184
Query: 182 QKMPT---------SWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPP 232
+ +PT L + +SVI ++ +S E SCT+R+ + + +++ P
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVI-MRGSSGE---GVSCTIRSSLLGLEKTASISIADP 240
Query: 233 SNKA-----GLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIRE 279
++ +AG + LL L G ++ +++++ + +K+ ++RE
Sbjct: 241 FFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELRE 292
>gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Homo
sapiens]
Length = 378
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/292 (21%), Positives = 127/292 (43%), Gaps = 32/292 (10%)
Query: 5 LCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKF--TLSPEDQGPLDIEWLISPA 62
+C +LL ++ + S+ P I GE A LPC T+S E ++++W+ S
Sbjct: 16 VCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAET---MELKWVSS-- 70
Query: 63 DNQKVDQVIILYS-GDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
+ QV+ +Y+ G ++ D +GR + + +G A++ + N+ SD G Y C
Sbjct: 71 ---SLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCY 127
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDS 181
+ + L V S V G ++ G ++C Q +W +
Sbjct: 128 FQDGDFYEKALVELKVAALGSDLHVDVKGYKDGG--IHLECRSTGWYPQPQIQWSN-NKG 184
Query: 182 QKMPT---------SWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPP 232
+ +PT L + +SVI ++ +S E SCT+R+ + + +++ P
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVI-MRGSSGE---GVSCTIRSSLLGLEKTASISIADP 240
Query: 233 SNKA-----GLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIRE 279
++ +AG + LL L G ++ +++++ + +K+ ++RE
Sbjct: 241 FFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELRE 292
>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
sapiens]
Length = 513
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/292 (21%), Positives = 127/292 (43%), Gaps = 32/292 (10%)
Query: 5 LCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKF--TLSPEDQGPLDIEWLISPA 62
+C +LL ++ + S+ P I GE A LPC T+S E ++++W+ S
Sbjct: 16 VCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAET---MELKWVSS-- 70
Query: 63 DNQKVDQVIILYS-GDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCK 121
+ QV+ +Y+ G ++ D +GR + + +G A++ + N+ SD G Y C
Sbjct: 71 ---SLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCY 127
Query: 122 VKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDS 181
+ + L V S V G ++ G ++C Q +W +
Sbjct: 128 FQDGDFYEKALVELKVAALGSDLHVDVKGYKDGG--IHLECRSTGWYPQPQIQWSN-NKG 184
Query: 182 QKMPT---------SWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPP 232
+ +PT L + +SVI ++ +S E SCT+R+ + + +++ P
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVI-MRGSSGE---GVSCTIRSSLLGLEKTASISIADP 240
Query: 233 SNKA-----GLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIRE 279
++ +AG + LL L G ++ +++++ + +K+ ++RE
Sbjct: 241 FFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELRE 292
>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
[Homo sapiens]
Length = 527
Score = 54.3 bits (129), Expect = 2e-07
Identities = 68/299 (22%), Positives = 120/299 (40%), Gaps = 42/299 (14%)
Query: 2 ALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGP-LDIEWLIS 60
+LLL + LC +V + + P + I GE L C LSPE +++ W S
Sbjct: 14 SLLLLLLSLCALV--SAQFIVVGPTDPILATVGENTTLRCH--LSPEKNAEDMEVRWFRS 69
Query: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC 120
Q V + G + ++ + +GR F S D+ G ++ + N+ + GTY+C
Sbjct: 70 ----QFSPAVFVYKGGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQENGTYRC 125
Query: 121 KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC--------------EPKE 166
++ +HLVV S + G E+ G +++C +P
Sbjct: 126 YFQEGRSYDEAILHLVVAGLGSKPLISMRGHEDGG--IRLECISRGWYPKPLTVWRDPYG 183
Query: 167 GSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRV---GSDQC 223
G P E MP + M ++ + +++ S SC++ N + +
Sbjct: 184 GVAPALKE-------VSMPDADGLFMVTTAVIIRDKSVR---NMSCSINNTLLGQKKESV 233
Query: 224 LLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKY---EKEVHHDIRE 279
+ PS +A II +L + I + I+ K ++E+K EKE + RE
Sbjct: 234 IFIPESFMPSVSPCAVALPIIVVILMIP-IAVCIYWINKLQKEKKILSGEKEFERETRE 291
>gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2
precursor [Homo sapiens]
Length = 334
Score = 54.3 bits (129), Expect = 2e-07
Identities = 68/299 (22%), Positives = 120/299 (40%), Gaps = 42/299 (14%)
Query: 2 ALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGP-LDIEWLIS 60
+LLL + LC +V + + P + I GE L C LSPE +++ W S
Sbjct: 14 SLLLLLLSLCALV--SAQFIVVGPTDPILATVGENTTLRCH--LSPEKNAEDMEVRWFRS 69
Query: 61 PADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQC 120
Q V + G + ++ + +GR F S D+ G ++ + N+ + GTY+C
Sbjct: 70 ----QFSPAVFVYKGGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQENGTYRC 125
Query: 121 KVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKC--------------EPKE 166
++ +HLVV S + G E+ G +++C +P
Sbjct: 126 YFQEGRSYDEAILHLVVAGLGSKPLISMRGHEDGG--IRLECISRGWYPKPLTVWRDPYG 183
Query: 167 GSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRV---GSDQC 223
G P E MP + M ++ + +++ S SC++ N + +
Sbjct: 184 GVAPALKE-------VSMPDADGLFMVTTAVIIRDKSVR---NMSCSINNTLLGQKKESV 233
Query: 224 LLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKY---EKEVHHDIRE 279
+ PS +A II +L + I + I+ K ++E+K EKE + RE
Sbjct: 234 IFIPESFMPSVSPCAVALPIIVVILMIP-IAVCIYWINKLQKEKKILSGEKEFERETRE 291
>gi|6005958 V-set and immunoglobulin domain containing 4 isoform 1
[Homo sapiens]
Length = 399
Score = 52.8 bits (125), Expect = 5e-07
Identities = 66/237 (27%), Positives = 104/237 (43%), Gaps = 31/237 (13%)
Query: 1 MALLLCFVLLCGV-VDFARSLSITTPEEMIEKAKGETAYLPCKFTLSP-EDQGPLDIEWL 58
M +LL +LL + VD + PE + KG+ LPC T P + + ++WL
Sbjct: 1 MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVN-LPC--TYDPLQGYTQVLVKWL 57
Query: 59 ISPADNQKVDQVIILY---SGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDI 115
+ D V I SGD I Y +GR+H + GD S+ ++ L++ D
Sbjct: 58 VQRGS----DPVTIFLRDSSGDHIQQAKY---QGRLHVSHK--VPGDVSLQLSTLEMDDR 108
Query: 116 GTYQCKVK-KAPG---VANKKIHLVVLVKPSGARCYVDGSEEIGSD------FKIKCEPK 165
Y C+V + P V KI + + K S ++ V G ++C+ +
Sbjct: 109 SHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR 168
Query: 166 EGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQ 222
GS P+ Y W K + + P + T S + K A SG+Y CT + +VGS+Q
Sbjct: 169 -GSPPISYIWYKQQTNNQEP---IKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 52.8 bits (125), Expect = 5e-07
Identities = 56/283 (19%), Positives = 112/283 (39%), Gaps = 41/283 (14%)
Query: 98 LKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKK-IHLVV--------LVKPSGARCYV 148
L + + ++ + LQ +D G Y C+V A + + L + + + S +
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
Query: 149 DGSEEIGSDFKIKC--EPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEY 206
E+ S ++C E K G+ +Y W + E + ++ + E+
Sbjct: 362 TIEAELNSSLTLQCWAESKPGA---EYRWTLEHST--------GEHLGEQLIIRALTWEH 410
Query: 207 SGTYSCTVRNRVG--SDQCLLRLNVVPPSNKA---GLIAGAIIGTLLALAL---IGLIIF 258
G Y+CT N + + + + VV P + + G IAG +IG L +A+ +G ++
Sbjct: 411 DGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLY 470
Query: 259 CCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGS---------MSPSN 309
+R K ++ H+ + +P + T + + + ++ M P +
Sbjct: 471 IRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPD 530
Query: 310 MEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIP 352
+ +T ++PS SP PP K P L + +P
Sbjct: 531 LP--EETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVP 571
Score = 31.2 bits (69), Expect = 1.5
Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 28/150 (18%)
Query: 86 DLKGRVHFTSNDLK---------SGDASI-NVTNLQLSDIGTYQCKVKKA-PGVANKKIH 134
D+ +H+ SN+L S D I + +Q D GTYQC+ + A + I
Sbjct: 94 DVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
Query: 135 LVVLVKPSGARCYVD---GSEEI-----GSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPT 186
L V P ++ S E+ GS E K P Y W L
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHP-PCAYTWFLLDS------ 206
Query: 187 SWLAEMTSSVISVKNASSEYSGTYSCTVRN 216
+ T+ ++ S E+ G Y C V N
Sbjct: 207 --ILSHTTRTFTIHAVSREHEGLYRCLVSN 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,021,550
Number of Sequences: 37866
Number of extensions: 692805
Number of successful extensions: 3781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 2472
Number of HSP's gapped (non-prelim): 1264
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.