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Search of human proteins with 42560237
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo
sapiens]
(517 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 1065 0.0
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 691 0.0
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 686 0.0
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 235 8e-62
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 213 4e-55
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 197 2e-50
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 184 2e-46
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 184 2e-46
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 179 5e-45
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 174 1e-43
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 150 4e-36
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 84 2e-16
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 84 3e-16
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 80 6e-15
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 80 6e-15
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 77 3e-14
gi|90903245 CD200 antigen isoform b [Homo sapiens] 69 1e-11
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens] 69 1e-11
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 68 2e-11
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 65 1e-10
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 61 2e-09
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 61 2e-09
gi|126517478 peroxidasin homolog-like [Homo sapiens] 60 6e-09
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 57 4e-08
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 57 4e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 57 4e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 57 4e-08
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 57 5e-08
gi|67188443 CD276 antigen isoform a [Homo sapiens] 53 6e-07
gi|166295173 kin of IRRE like [Homo sapiens] 53 6e-07
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 1065 bits (2754), Expect = 0.0
Identities = 517/517 (100%), Positives = 517/517 (100%)
Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV 360
FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV 360
Query: 361 AGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPD 420
AGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPD
Sbjct: 361 AGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQHHPPMAQNLQYPD 420
Query: 421 DSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDG 480
DSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDG
Sbjct: 421 DSDDEKKAGPLGGSSYEEEEEEEEGGGGGERKVGGPHPKYDEDAKRPYFTVDEAEARQDG 480
Query: 481 YGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV 517
YGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV
Sbjct: 481 YGDRTLGYQYDPEQLDLAENMVSQNDGSFISKKEWYV 517
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 691 bits (1782), Expect = 0.0
Identities = 344/370 (92%), Positives = 350/370 (94%), Gaps = 6/370 (1%)
Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGV 360
FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITE P P+ G G + G V
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEKP----RPQRG--LGSAARLLAGTV 354
Query: 361 AGSILLVLIV 370
A ++LV ++
Sbjct: 355 AVFLILVAVL 364
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 686 bits (1769), Expect = 0.0
Identities = 335/336 (99%), Positives = 335/336 (99%)
Query: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV
Sbjct: 1 MARMGLAGAAGRWWGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSV 60
Query: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG
Sbjct: 61 KITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEG 120
Query: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP
Sbjct: 121 VYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT
Sbjct: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLT 240
Query: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL
Sbjct: 241 LNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTL 300
Query: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEF 336
FFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT F
Sbjct: 301 FFKGPINYSLAGTYICEATNPIGTRSGQVEVNITAF 336
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 235 bits (599), Expect = 8e-62
Identities = 161/492 (32%), Positives = 238/492 (48%), Gaps = 64/492 (13%)
Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGV 121
ITQ++W+K S Q VA+++P G SV Y+ RV F S D TI L + D G
Sbjct: 86 ITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGK 145
Query: 122 YICEFATFPTGNRESQLNLTVMAKPT-NWIEGTQAVLRAKKGQDDKVLVATCTSANGKPP 180
YIC+ TFP GN +S +TV+ +PT + I+G +++ ++ + A C +A GKP
Sbjct: 146 YICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDG----GNETVAAICIAATGKPV 201
Query: 181 SVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKES 238
+ + WE L GE E PN T T+IS+Y+L P+R A + + C+V + + S
Sbjct: 202 AHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYS 260
Query: 239 LTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNR 298
L++QY PEV++ G+DGNW++ R V L C ADANPP + W+ L+G P G+ A +
Sbjct: 261 FILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDN 320
Query: 299 TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYT----PSPPEHGRRAG---- 350
TL F P+ ++ +G YIC+ TN +G RS Q + I++ P T P+ H A
Sbjct: 321 TLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDL 380
Query: 351 -------PVP-------------TAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYS 390
P P T I V G++ +VL+ V + RRRR TF+GDY
Sbjct: 381 ATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRR-TFRGDYF 439
Query: 391 TKKHVYGNGYSKAGIPQHHPPMAQNL-QYPDDSDDEKK--AGPLGGSSYEEEEEEEEGGG 447
K ++ + K Q L YPD E K L Y EE E+ +
Sbjct: 440 AKNYIPPSDMQKES--QIDVLQQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNN 497
Query: 448 GGERKVGGPHPKYDEDAKRPYFTVDEAEARQDGYGDRTLGYQY--DPEQLDLAENMVSQN 505
++ E D Y D +G ++ D + +++VS
Sbjct: 498 --------------------VENLNRFERPMDYYEDLKMGMKFVSDEHYDENEDDLVSHV 537
Query: 506 DGSFISKKEWYV 517
DGS IS++EWYV
Sbjct: 538 DGSVISRREWYV 549
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 213 bits (541), Expect = 4e-55
Identities = 154/451 (34%), Positives = 220/451 (48%), Gaps = 62/451 (13%)
Query: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85
G VQV + G +G V L C P+P + I+ VTWQ+ + QNVA ++P M
Sbjct: 30 GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
Query: 86 GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
G S +P ER+ F+ D T+ L L +EDEG Y CEFATFP G+
Sbjct: 90 GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193
L V+AKP N E + D VA C S G+PP+ +SW + L EA
Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248
+ ++ GTVTV SR+ LVPS A ++ C V + + F+E +TL+V+Y PE
Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308
V+I G+D NWYL R D L+C +NP T Y W+T +G+ P AQ L ++
Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
Query: 309 SLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVL 368
T++C TN +G + + + E P SP R GP+ + G V G++L++L
Sbjct: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETP-RASP----RDVGPL---VWGAVGGTLLVLL 373
Query: 369 IVVGG----IVVALRRRRHT-------FKGD---YSTKKHVYGNGYSKAGIPQHHPPMAQ 414
++ GG I++ +RRRR + GD Y K V GN G P P+
Sbjct: 374 LLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGN-----GDPVFWTPVVP 428
Query: 415 NLQYPDDSDDEKKAGPLGGSSYEEEEEEEEG 445
PD D+E++ EEEE+ E+G
Sbjct: 429 GPMEPDGKDEEEE---------EEEEKAEKG 450
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 197 bits (501), Expect = 2e-50
Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 34/374 (9%)
Query: 27 GVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQK-STNGSKQNVAIYNPSM 85
G VQV + G +G V L C P+P + I+ VTWQ+ + QNVA ++P M
Sbjct: 30 GAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKM 89
Query: 86 GVSVLAPY--RERVEFL----------RPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
G S +P ER+ F+ D T+ L L +EDEG Y CEFATFP G+
Sbjct: 90 GPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGS 149
Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEA 193
L V+AKP N E + D VA C S G+PP+ +SW + L EA
Sbjct: 150 VRGMTWLRVIAKPKNQAEAQKVTF-----SQDPTTVALCISKEGRPPARISWLSSLDWEA 204
Query: 194 EYQEIRNP-NGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKES----LTLNVQYEPE 248
+ ++ GTVTV SR+ LVPS A ++ C V + + F+E +TL+V+Y PE
Sbjct: 205 KETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEH--ESFEEPALIPVTLSVRYPPE 262
Query: 249 VTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINY 308
V+I G+D NWYL R D L+C +NP T Y W+T +G+ P AQ L ++
Sbjct: 263 VSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHA-VDS 321
Query: 309 SLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVL 368
T++C TN +G + + + E P T G IIGG+ +I+
Sbjct: 322 LFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAGATG--------GIIGGIIAAIIATA 373
Query: 369 IVVGGIVVALRRRR 382
+ GI++ ++R+
Sbjct: 374 VAATGILICRQQRK 387
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 184 bits (466), Expect = 2e-46
Identities = 130/378 (34%), Positives = 195/378 (51%), Gaps = 29/378 (7%)
Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPT 354
AQ L + P++ + T IC TN +G R ++ V + E P P EH +G
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH---SGISRN 343
Query: 355 AIIGGVAGSILLVLIVVG 372
AII V G IL+ LI++G
Sbjct: 344 AIIFLVLG-ILVFLILLG 360
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 184 bits (466), Expect = 2e-46
Identities = 130/378 (34%), Positives = 195/378 (51%), Gaps = 29/378 (7%)
Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPT 354
AQ L + P++ + T IC TN +G R ++ V + E P P EH +G
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH---SGISRN 343
Query: 355 AIIGGVAGSILLVLIVVG 372
AII V G IL+ LI++G
Sbjct: 344 AIIFLVLG-ILVFLILLG 360
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 179 bits (454), Expect = 5e-45
Identities = 119/351 (33%), Positives = 180/351 (51%), Gaps = 25/351 (7%)
Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEH 345
AQ L + P++ + T IC TN +G R ++ V + E P P EH
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQVKEGP----PSEH 337
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 174 bits (442), Expect = 1e-43
Identities = 114/339 (33%), Positives = 175/339 (51%), Gaps = 21/339 (6%)
Query: 6 LAGAAGRWWGL---ALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVK- 61
+A A W L AL + ++ PG VVQ + GF+G V L C P V
Sbjct: 1 MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTH 60
Query: 62 ITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEF----LRPSFTDGTIRLSRLELE 117
++Q+TW + +G ++A+++ + G S +R+EF L + ++R+ L +E
Sbjct: 61 VSQLTWAR--HGESGSMAVFHQTQGPSYSES--KRLEFVAARLGAELRNASLRMFGLRVE 116
Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
DEG Y C F TFP G+R + L V+AKP N E + L + V +A C S G
Sbjct: 117 DEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTG-----EPVPMARCVSTGG 171
Query: 178 KPPSVVSWETRLKGEAEYQEIRN-PNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
+PP+ ++W + L G ++ +GTVTV S + LVPS + +++ C V +
Sbjct: 172 RPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
Query: 237 ESLTLN--VQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKGVE 294
+ LT+N V Y PEV+I G+D NWYL + + LTC A +NP T Y+W+T G LP
Sbjct: 232 QLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAV 291
Query: 295 AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
AQ L + P++ + T IC TN +G R ++ V +
Sbjct: 292 AQGAQLLIR-PVDKPINTTLICNVTNALGARQAELTVQV 329
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 150 bits (378), Expect = 4e-36
Identities = 118/403 (29%), Positives = 192/403 (47%), Gaps = 29/403 (7%)
Query: 4 MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59
M L+ A W W L L L A F + ++ +D + +G D L C +
Sbjct: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59
Query: 60 VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116
++ QV W + G Q +A+ + G+ V Y RVE P DG++ L
Sbjct: 60 EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119
Query: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
DEG Y C +TFP G+ +++L L V+ P + A+ ++GQ L A+CT A
Sbjct: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174
Query: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
G P V+W+T +KG + ++ + + V S + LVPSR + Q L C+V++
Sbjct: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
Query: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
+ +T L+V + E ++ G + W++ R L C ++ PP + Y+WT L+G LP G
Sbjct: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292
Query: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPV 352
V TL F P+ +G Y+C +N +R QV V++ + + G++ V
Sbjct: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD-----PQEDSGKQVDLV 346
Query: 353 -PTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKH 394
+ ++ GV ++L L+VV VV L R H K T+K+
Sbjct: 347 SASVVVVGVIAALLFCLLVV---VVVLMSRYHRRKAQQMTQKY 386
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 84.3 bits (207), Expect = 2e-16
Identities = 84/321 (26%), Positives = 136/321 (42%), Gaps = 30/321 (9%)
Query: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKDT-AVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKESLTLNVQYEPE 248
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 188 GKSEVEEWSD---MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
Query: 249 VTIEGFDGNWYLQRMD--VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPI 306
V I+ L R ++LTC+A P W ++ +P+ LF +
Sbjct: 245 VHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINN-L 303
Query: 307 NYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAII--------G 358
N + GTY CEA+N +G + + + P T PP T I
Sbjct: 304 NKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRA 363
Query: 359 GVAGSILLV-LIVVGGIVVAL 378
G GSI V V+GG+V +
Sbjct: 364 GEEGSIRAVDHAVIGGVVAVV 384
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 84.0 bits (206), Expect = 3e-16
Identities = 84/328 (25%), Positives = 143/328 (43%), Gaps = 35/328 (10%)
Query: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
Query: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
Query: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
Query: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
Query: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGS 363
+N + GTY CEA+N + G+ + + Y E G V A+IGGV
Sbjct: 302 N-LNKTDNGTYRCEASNIV----GKAHSDYMLYVYDSRAGEEG-SIRAVDHAVIGGVVAV 355
Query: 364 ILLVLIVVGGIVVALRRRRHTFKGDYST 391
++ ++ +++ L R KG Y T
Sbjct: 356 VVFAMLC---LLIILGRYFARHKGTYFT 380
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 79.7 bits (195), Expect = 6e-15
Identities = 88/306 (28%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 82 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 139
Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 140 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 192
Query: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265
+RE S+ C VN+ DR S + V Y P I D + +
Sbjct: 193 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 250
Query: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 251 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 308
Query: 326 SGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTF 385
+N+ + PSP + AIIGG+ I+ +L++ +++ L
Sbjct: 309 KAYYTLNVND----PSPVP---SSSSTYHAIIGGIVAFIVFLLLI---MLIFLGHYLIRH 358
Query: 386 KGDYST 391
KG Y T
Sbjct: 359 KGTYLT 364
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 79.7 bits (195), Expect = 6e-15
Identities = 88/306 (28%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 116 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 173
Query: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 174 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 226
Query: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265
+RE S+ C VN+ DR S + V Y P I D + +
Sbjct: 227 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 284
Query: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 285 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 342
Query: 326 SGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTF 385
+N+ + PSP + AIIGG+ I+ +L++ +++ L
Sbjct: 343 KAYYTLNVND----PSPVP---SSSSTYHAIIGGIVAFIVFLLLI---MLIFLGHYLIRH 392
Query: 386 KGDYST 391
KG Y T
Sbjct: 393 KGTYLT 398
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 77.4 bits (189), Expect = 3e-14
Identities = 91/331 (27%), Positives = 138/331 (41%), Gaps = 44/331 (13%)
Query: 78 VAIYNPSM------GVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPT 131
V I NP+ G L R ++E P IRLS LEDEG Y C+ T T
Sbjct: 54 VVIQNPARQTLFFNGTRALKDERFQLEEFSPRRV--RIRLSDARLEDEGGYFCQLYTEDT 111
Query: 132 GNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETR 188
++ + LTV+ P N + + +A +G + ++ +C +P + + W
Sbjct: 112 HHQIA--TLTVLVAPENPVVEVRE--QAVEGGEVEL---SCLVPRSRPAATLRWYRDRKE 164
Query: 189 LKGEAEYQEIRNPNGTV-TVISRYRLVPSREAHQQSLACIVNYHM----DRFKESLTLNV 243
LKG + QE NG V +V S R R+ + C + L+V
Sbjct: 165 LKGVSSSQE----NGKVWSVASTVRFRVDRKDDGGIIICEAQNQALPSGHSKQTQYVLDV 220
Query: 244 QYEPEVTIEGFDGNWYLQRMD-VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFF 302
QY P I ++ D + LTC NP + W N SLP+ EA TL
Sbjct: 221 QYSPTARIHASQA--VVREGDTLVLTCAVTGNPRPNQIRWNRGNESLPERAEAVGETLTL 278
Query: 303 KGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAG 362
G ++ GTY CEA+N + G Y P + + VP AI+GG+
Sbjct: 279 PGLVSAD-NGTYTCEASN----KHGHARALYVLVVYDPGAVVEAQTS--VPYAIVGGILA 331
Query: 363 SI--LLVLIVVGGIVVALRRRRHTFKGDYST 391
+ L++ ++VG + ++R+ KG Y T
Sbjct: 332 LLVFLIICVLVGMVWCSVRQ-----KGSYLT 357
>gi|90903245 CD200 antigen isoform b [Homo sapiens]
Length = 294
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%)
Query: 45 TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104
T L CS N ++ VTWQK S +N+ ++ + GV + Y++++ +
Sbjct: 70 TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 126
Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
+ TI + LEDEG Y+C F TF G LTV +P L K +D
Sbjct: 127 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 179
Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223
L TC SA +P +V W+ G E + +PNGT +V S + + +
Sbjct: 180 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 236
Query: 224 LACIV 228
+ C V
Sbjct: 237 VICQV 241
>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
Length = 269
Score = 68.9 bits (167), Expect = 1e-11
Identities = 53/185 (28%), Positives = 81/185 (43%), Gaps = 14/185 (7%)
Query: 45 TDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSF 104
T L CS N ++ VTWQK S +N+ ++ + GV + Y++++ +
Sbjct: 45 TPASLKCSLQNAQEALI---VTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGL 101
Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
+ TI + LEDEG Y+C F TF G LTV +P L K +D
Sbjct: 102 QNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPI-------VSLHYKFSED 154
Query: 165 DKVLVATCTSANGKPPSVVSWETRLKG-EAEYQEIRNPNGTVTVISRYRLVPSREAHQQS 223
L TC SA +P +V W+ G E + +PNGT +V S + + +
Sbjct: 155 H--LNITC-SATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKE 211
Query: 224 LACIV 228
+ C V
Sbjct: 212 VICQV 216
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 67.8 bits (164), Expect = 2e-11
Identities = 66/257 (25%), Positives = 106/257 (41%), Gaps = 20/257 (7%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
R+E +R S+ + +I +S + L DEG Y C T P + S+ LTV+ P E Q
Sbjct: 78 RIELVRASWHELSISVSDVSLSDEGQYTCSLFTMPV--KTSKAYLTVLGVP----EKPQI 131
Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYR 212
+ + ++ TC ++ KP + + W + +K +E T TV S
Sbjct: 132 SGFSSPVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLD 191
Query: 213 LVPSREAHQQSLACIVNYHMDRFKESL---TLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
R ++ C V++ + L + Y P V I + + + LTC
Sbjct: 192 FRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIP-STPFPQEGQPLILTC 250
Query: 270 KADANPPATEYHWTTLNGSLPKG----VEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
++ P WT G LP V + + F +N + GTY CEATN IG
Sbjct: 251 ESKGKPLPEPVLWTKDGGELPDPDRMVVSGRELNILF---LNKTDNGTYRCEATNTIGQS 307
Query: 326 SGQVEVNITEFPYTPSP 342
S + + + + P T P
Sbjct: 308 SAEYVLIVHDVPNTLLP 324
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 65.5 bits (158), Expect = 1e-10
Identities = 76/322 (23%), Positives = 127/322 (39%), Gaps = 40/322 (12%)
Query: 47 VVLHCSFANPLPSVKITQVTWQKS-----TNGSKQNVAIYNPSMGVSVLAPYRERVEFLR 101
V + S P+P+ + Q + ++ T G ++ P + + Y+
Sbjct: 2908 VTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPA 2967
Query: 102 PSFTDGT-IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRA- 159
T G+ +RL + D G Y+C A+ P +E+ +TV EG+ LR+
Sbjct: 2968 RHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPS-----EGSSYRLRSP 3022
Query: 160 -----------KKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVI 208
++GQD C +G P + W+TR E E +PNG++ I
Sbjct: 3023 VISIDPPSSTVQQGQDASF---KCLIHDGAAPISLEWKTR-NQELEDNVHISPNGSIITI 3078
Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268
V +R ++ + C+ + + + L+V P V++ W V L
Sbjct: 3079 -----VGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLE 3133
Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPI------NYSLAGTYICEATNPI 322
C A P + WT ++ S P +E + L + S AGTY+C A N +
Sbjct: 3134 C-VSAGEPRSSARWTRIS-STPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191
Query: 323 GTRSGQVEVNITEFPYTPSPPE 344
GT QVEV + P P+
Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQ 3213
Score = 50.4 bits (119), Expect = 4e-06
Identities = 77/334 (23%), Positives = 122/334 (36%), Gaps = 62/334 (18%)
Query: 20 LTAFFLPGVHSQVVQVNDSMYG-FIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNV 78
L A +P + VQV + IG V HC+ +PS + TQ+ W K
Sbjct: 3389 LPATSIPAGSTPTVQVTPQLETKSIGASVEFHCA----VPSDRGTQLRWFKEGGQ----- 3439
Query: 79 AIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQL 138
L P S DG +R+ L+ +G YIC+ A P G ++
Sbjct: 3440 -----------LPPGH--------SVQDGVLRIQNLDQSCQGTYICQ-AHGPWGKAQASA 3479
Query: 139 NLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEI 198
L + A P+ I +V G V A G P V+W +++ G +
Sbjct: 3480 QLVIQALPSVLINIRTSVQTVVVGH----AVEFECLALGDPKPQVTW-SKVGGHLRPGIV 3534
Query: 199 RNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNW 258
++ G V I+ L + + C + + L VQ P++++
Sbjct: 3535 QS--GGVVRIAHVELADAGQYR-----CTATNAAGTTQSHVLLLVQALPQISMP------ 3581
Query: 259 YLQRMDVKLTCKADA-------NPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA 311
+V++ + A P + W+ L+GSLP +N L + A
Sbjct: 3582 ----QEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPS-VRPQDA 3636
Query: 312 GTYICEATNPIGTRSGQVEVNITE--FPYTPSPP 343
GTY+C ATN G + + E PY P
Sbjct: 3637 GTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTP 3670
Score = 50.1 bits (118), Expect = 5e-06
Identities = 60/252 (23%), Positives = 96/252 (38%), Gaps = 26/252 (10%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV----MAKPTNWIEGTQAVLRAKKGQD 164
+++S + D G Y+C A G + Q+ + V MA ++ +A L + G
Sbjct: 3170 LQISSAKPSDAGTYVC-LAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGH- 3227
Query: 165 DKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQS- 223
C SA G P + W ++R+P + L+ R A Q S
Sbjct: 3228 --TATLRC-SATGSPAPTIHWS----------KLRSPLPWQHRLEGDTLIIPRVAQQDSG 3274
Query: 224 -LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHW 282
C + ++ L+V+ P T + V+L C A PP T + W
Sbjct: 3275 QYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGET-VQLQCLAHGTPPLT-FQW 3332
Query: 283 TTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSP 342
+ + SLP A+N L F+ +G Y C TN +G+ ++ + P S
Sbjct: 3333 SRVGSSLPGRATARNELLHFERAAPED-SGRYRCRVTNKVGSAEAFAQLLVQGPP--GSL 3389
Query: 343 PEHGRRAGPVPT 354
P AG PT
Sbjct: 3390 PATSIPAGSTPT 3401
Score = 47.0 bits (110), Expect = 4e-05
Identities = 57/241 (23%), Positives = 94/241 (39%), Gaps = 31/241 (12%)
Query: 118 DEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANG 177
+ G Y C A+ G +S +NL+V PT + + + K G K + C SA G
Sbjct: 3085 NHGTYRC-VASNAYGVAQSVVNLSVHGPPTVSVL-PEGPVWVKVG---KAVTLECVSA-G 3138
Query: 178 KPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFKE 237
+P S W TR+ E R G + + ++ ++ + + C+ + ++
Sbjct: 3139 EPRSSARW-TRISSTPAKLEQRT-YGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQK 3196
Query: 238 SLTLNVQY-------------EPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTT 284
+ + V E E+T+E L C A +P T HW+
Sbjct: 3197 QVEVIVDTGAMAPGAPQVQAEEAELTVEAGH--------TATLRCSATGSPAPT-IHWSK 3247
Query: 285 LNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPE 344
L LP + TL +G YIC AT+P G + +++ PY + PE
Sbjct: 3248 LRSPLPWQHRLEGDTLIIPRVAQQD-SGQYICNATSPAGHAEATIILHVESPPYATTVPE 3306
Query: 345 H 345
H
Sbjct: 3307 H 3307
Score = 44.7 bits (104), Expect = 2e-04
Identities = 64/262 (24%), Positives = 97/262 (37%), Gaps = 33/262 (12%)
Query: 106 DGTIRLSRLELEDEGVYICEFATF-----PTGNRESQLNLTVMAKPTNWIEGTQAVLRAK 160
+G + + ++L D G Y+C + T Q + T+ A P I Q L +
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSA-PVVSIHPPQ--LTVQ 1878
Query: 161 KGQDDKVLVATCTSANGKPPSVVSW------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
GQ L SA G P + W + K + +R P T ++Y
Sbjct: 1879 PGQ----LAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCR 1934
Query: 215 PSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADAN 274
A QQ +++ H VQ PE T + G V+L C+A
Sbjct: 1935 AHSSAGQQVARAVLHVHGGGGPR-----VQVSPERT-QVHAGR------TVRLYCRAAGV 1982
Query: 275 PPATEYHWTTLNGSLPKGVEAQNRTL--FFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
P AT W GSLP ++ + I + AG Y+C AT+P GT +++V
Sbjct: 1983 PSAT-ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVV 2041
Query: 333 ITEFPYTPSPPEHGRRAGPVPT 354
+ PP + P T
Sbjct: 2042 VLSASDASPPPVKIESSSPSVT 2063
Score = 37.0 bits (84), Expect = 0.043
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 264 DVKLTCKADANPPATEYHWTTL-NGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPI 322
DV C A + PA WT L NG LP N L + + S AGTY+C +N
Sbjct: 1788 DVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRN-VQLSDAGTYVCTGSNMF 1846
Query: 323 GTRSGQVEVNI 333
G +++
Sbjct: 1847 AMDQGTATLHV 1857
Score = 36.6 bits (83), Expect = 0.057
Identities = 55/255 (21%), Positives = 93/255 (36%), Gaps = 39/255 (15%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTV-----------MAKPTNWIEGTQAVL 157
+RL ++ D G Y+C +G +E+ + +T+ +A P IE + A L
Sbjct: 2488 LRLLQVTPADSGEYVCRVVG-SSGTQEASVLVTIQQRLSGSHSQGVAYPVR-IESSSASL 2545
Query: 158 RAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSR 217
D LVA+ + P ++W R +I V SR R+
Sbjct: 2546 ANGHTLDLNCLVAS------QAPHTITWYKRGGSLPSRHQI--------VGSRLRIPQVT 2591
Query: 218 EAHQQSLACIVNYHMDRFKESLTLNVQ---------YEPEVTIEGFDGNWYLQRMDVKLT 268
A C V+ + SL + +Q P + IE ++ + L
Sbjct: 2592 PADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPT-VVEGQTLDLN 2650
Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQ 328
C P A W GSLP + L ++ + +G Y+C A N I
Sbjct: 2651 CVVARQPQAI-ITWYKRGGSLPSRHQTHGSHLRLH-QMSVADSGEYVCRANNNIDALEAS 2708
Query: 329 VEVNITEFPYTPSPP 343
+ ++++ +PS P
Sbjct: 2709 IVISVSPSAGSPSAP 2723
Score = 33.5 bits (75), Expect = 0.48
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 267 LTCKADANPPATEYHWTTLNGS-LPKGVEAQNRTLFFKGP-INYSLAGTYICEATNPIGT 324
L C+ +PP ++W+ +G +P G + +++ P + S AG YIC N +
Sbjct: 1696 LRCQVSGSPPHY-FYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQS 1754
Query: 325 RSGQVEVNITEFPYTP 340
+ + E+ +TE P P
Sbjct: 1755 NTSRAELLVTEAPSKP 1770
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 265 VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGT 324
V+ C A P + W+ + G L G+ Q+ + + + AG Y C ATN GT
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVGGHLRPGI-VQSGGVVRIAHVELADAGQYRCTATNAAGT 3563
Query: 325 RSGQVEVNITEFPYTPSPPE 344
V + + P P E
Sbjct: 3564 TQSHVLLLVQALPQISMPQE 3583
Score = 30.0 bits (66), Expect = 5.3
Identities = 22/98 (22%), Positives = 37/98 (37%), Gaps = 14/98 (14%)
Query: 261 QRMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATN 320
Q +D+ A+ T W GSLP + L ++ + +G Y+C N
Sbjct: 2066 QTLDLNCVVAGSAHAQVT---WYRRGGSLPPHTQVHGSRLRLP-QVSPADSGEYVCRVEN 2121
Query: 321 PIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIG 358
G + + V++ HG +GP T + G
Sbjct: 2122 GSGPKEASITVSVL----------HGTHSGPSYTPVPG 2149
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ R EL+D+ VY C+ R LTV+ P + + V+ + G L
Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166
Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
TC + N KP + + W + + G + + +++S + P + QS+
Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226
Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
C N + KE S+T+++Q+ P V + + L+ V C A ANP T+Y W
Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285
Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYT 339
+ + RT +F P++ CE TN +G+ + V++ P
Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGSTNLSRTVDVYFGPRM 337
Query: 340 PSPPE 344
+ P+
Sbjct: 338 TTEPQ 342
Score = 38.9 bits (89), Expect = 0.011
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
T+ L + ED G Y+C G E ++ LTV P TQ L +KGQ
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437
Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
C + PP ++W E+ G + I G ++ ++ +V
Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/245 (23%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ R EL+D+ VY C+ R LTV+ P + + V+ + G L
Sbjct: 112 LKILRAELQDDAVYECQ--AIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDP---L 166
Query: 169 VATCTSANGKPPSVVSWETR---LKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
TC + N KP + + W + + G + + +++S + P + QS+
Sbjct: 167 NLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIV 226
Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
C N + KE S+T+++Q+ P V + + L+ V C A ANP T+Y W
Sbjct: 227 CRATNKAIPGGKETSVTIDIQHPPLVNLS-VEPQPVLEDNVVTFHCSAKANPAVTQYRWA 285
Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYT 339
+ + RT +F P++ CE TN +G+ + V++ P
Sbjct: 286 KRGQIIKEASGEVYRTTVDYTYFSEPVS--------CEVTNALGSTNLSRTVDVYFGPRM 337
Query: 340 PSPPE 344
+ P+
Sbjct: 338 TTEPQ 342
Score = 38.9 bits (89), Expect = 0.011
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 13/114 (11%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
T+ L + ED G Y+C G E ++ LTV P TQ L +KGQ
Sbjct: 382 TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQ---- 437
Query: 168 LVATCTSANGKPPSVVSW-------ETRLKGEAEYQEIRNPNGTVTVISRYRLV 214
C + PP ++W E+ G + I G ++ ++ +V
Sbjct: 438 --IKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 59.7 bits (143), Expect = 6e-09
Identities = 65/243 (26%), Positives = 103/243 (42%), Gaps = 35/243 (14%)
Query: 104 FTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNL----TVMAKPTNWIEGTQAVLRA 159
F DGT+ + D+GVY C A G ++Q + ++ AKP+ I+
Sbjct: 285 FDDGTLMIRNTRESDQGVYQC-MARNSAGEAKTQSAMLRYSSLPAKPSFVIQ-------- 335
Query: 160 KKGQDDKVLVATCTS----ANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVP 215
QD +VL+ T T+ A G P +++W TR G E+ T Y
Sbjct: 336 --PQDTEVLIGTSTTLECMATGHPHPLITW-TRDNG----LELDGSRHVATSSGLYLQNI 388
Query: 216 SREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANP 275
++ H + C N + + + VQ P+ T+ D L+ V+ C+AD NP
Sbjct: 389 TQRDHGR-FTCHANNSHGTVQAAANIIVQAPPQFTVTPKD-QVVLEEHAVEWLCEADGNP 446
Query: 276 PATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYICEATNPIGTRSGQVE 330
P WT G LP VE Q+ T+ G + A G Y C+A + +G + V+
Sbjct: 447 PPV-IVWTKTGGQLP--VEGQH-TVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQ 502
Query: 331 VNI 333
+ +
Sbjct: 503 LTV 505
Score = 30.4 bits (67), Expect = 4.1
Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 12/121 (9%)
Query: 65 VTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYIC 124
V W +G+ V ++ + G + VE + GT+R+ R D+G Y C
Sbjct: 436 VEWLCEADGNPPPVIVWTKTGG-------QLPVEGQHTVLSSGTLRIDRAAQHDQGQYEC 488
Query: 125 EFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVS 184
+ A G ++ + LTV K + G++ + +C A G+P +++
Sbjct: 489 Q-AVSSLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINI---SC-HAQGEPQPIIT 543
Query: 185 W 185
W
Sbjct: 544 W 544
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 57.0 bits (136), Expect = 4e-08
Identities = 88/376 (23%), Positives = 133/376 (35%), Gaps = 51/376 (13%)
Query: 54 ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSR 113
+NP+ T + T + I N S+ VS L+ S + T+ L
Sbjct: 154 SNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPR---------LQLSNGNRTLTLLS 204
Query: 114 LELEDEGVYICEFATFPTGNRESQLNLTVMAKP-TNWIEGTQAVLRAKKGQDDKVLVATC 172
+ D G Y CE + NR + L V P T I + R L +C
Sbjct: 205 VTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN-----LSLSC 259
Query: 173 TSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM 232
+A+ PP+ SW + QE+ PN TV Y + + + +
Sbjct: 260 YAASN-PPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318
Query: 233 DRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
+ + T+ G + V LTC N W N SLP
Sbjct: 319 TELSPVVAKPQIKASKTTVTG-------DKDSVNLTCST--NDTGISIRWFFKNQSLPSS 369
Query: 293 VE---AQNRTLFFKGPINYSLAGTYICEATNPIG-TRSGQVEVNITEFPYTPSPPEHGRR 348
+Q T P+ AGTY CE NPI +S + +N+ Y P E+G
Sbjct: 370 ERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVN---YNALPQENGLS 426
Query: 349 AGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIPQH 408
G +AG ++ V+ +V I VAL H K G + + +H
Sbjct: 427 P--------GAIAGIVIGVVALVALIAVALACFLHFGK---------TGRASDQRDLTEH 469
Query: 409 HPPMAQNLQYPDDSDD 424
P ++ + Q D S+D
Sbjct: 470 KPSVSNHTQ--DHSND 483
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 57.0 bits (136), Expect = 4e-08
Identities = 72/280 (25%), Positives = 106/280 (37%), Gaps = 41/280 (14%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
++L R + D GVY C+ A+ G E L V PT IEG K + +
Sbjct: 367 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 423
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
C A G P +SW AE E R +G+V RL EA +C+
Sbjct: 424 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 477
Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ ++ VQ P++ + EG + ++L C+A +P T W N
Sbjct: 478 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 535
Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI--------- 333
G + GV+ A T + +G + C+ATN GT +VEV++
Sbjct: 536 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVL 595
Query: 334 --------------TEFPYTPSPPEH-GRRAGPVPTAIIG 358
+ FP PP H G A P P + G
Sbjct: 596 EVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEG 635
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+ + ++ D+G+Y C+ + G LTV PT T+ V + L
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1951
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
V TC +G P V+W LK E +G V+ R +L + A + C+
Sbjct: 1952 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 2006
Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
++ + V P + G + L+ +V+L C+AD PP + W
Sbjct: 2007 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 2065
Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
L + + R +L KG + S AG Y C A NP G + VN+
Sbjct: 2066 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 2116
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 45/278 (16%)
Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
G +R++ ED G Y+C A G+ + L V P + EG+ A L
Sbjct: 2809 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2867
Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
K A G P ++W+ + Q + G T+ L+
Sbjct: 2868 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2907
Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
Q + C + R + + L + P T G+ L+ D + L C A +P
Sbjct: 2908 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2965
Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
WT + + +GV Q+ + + ++ +GTY+C A N +G V++
Sbjct: 2966 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024
Query: 335 EFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVG 372
E P G + ++ V GSI L +V G
Sbjct: 3025 EAPVL---------QGEAFSYLVEPVGGSIQLDCVVRG 3053
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ +++L DEG+Y C AT G + ++ L V+ P N G K +
Sbjct: 659 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 711
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C
Sbjct: 712 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 765
Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ + + L V P +T+ L V+LTC A P T N
Sbjct: 766 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 825
Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323
P G F G +LA G Y C A + +G
Sbjct: 826 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 866
Score = 38.5 bits (88), Expect = 0.015
Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
L + +L EG Y CE + GN L L V P I G + D V
Sbjct: 1031 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 1087
Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
C +A GKPP V+WE + G +++N ++ V ++ AH +C+
Sbjct: 1088 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1140
Query: 229 NYHMDRFKESLTLNVQYEPEV 249
R + L+V PE+
Sbjct: 1141 ENLAGRAERKFELSVLVPPEL 1161
Score = 38.1 bits (87), Expect = 0.019
Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%)
Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
+ + + + V L C A+P P +VTW K + S+G V
Sbjct: 1754 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1793
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
FL P T++L R L D G+Y CE A G + + L+V+ P A
Sbjct: 1794 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1839
Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+A +G D VLV A + P V+W + Q + G
Sbjct: 1840 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1895
Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
R + ++ + + +C V+ + TL VQ P + + + LTC
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1955
Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320
P T T L +P A + + G + S AGTY C A N
Sbjct: 1956 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008
Score = 37.4 bits (85), Expect = 0.033
Identities = 55/244 (22%), Positives = 86/244 (35%), Gaps = 21/244 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+R+ + +L D G Y C A+ G+ E + L V P + VL
Sbjct: 750 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 799
Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
V T +A G P + W LK P V R L +R +
Sbjct: 800 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 856
Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
+C+ + ++ + L V P + E + + + V L C++ A PP W
Sbjct: 857 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 915
Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPS 341
P+ GV + ++ L + AG Y CEA N G +N+ P P
Sbjct: 916 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPL 975
Query: 342 PPEH 345
H
Sbjct: 976 RESH 979
Score = 34.3 bits (77), Expect = 0.28
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
T+R+S+++L D G++ C A P G + L V P VL + Q+D V
Sbjct: 2177 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 2226
Query: 168 -----LVATCTSANGKPPSVVSW 185
LV A G P +VSW
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSW 2249
Score = 34.3 bits (77), Expect = 0.28
Identities = 55/267 (20%), Positives = 87/267 (32%), Gaps = 38/267 (14%)
Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P
Sbjct: 2522 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2576
Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+ L A + C ++ P VV W+ K + Q+
Sbjct: 2577 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2620
Query: 210 RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
YRL+PS C+V+ + + V P + + D +
Sbjct: 2621 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2680
Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
V LTC + P T W+ L G + G + A G Y C
Sbjct: 2681 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 2736
Query: 317 EATNPIGTRSGQVEVNITEFPYTPSPP 343
A N G V + + P P
Sbjct: 2737 SARNSAGVAHKHVFLTVQASPVVKPLP 2763
Score = 33.1 bits (74), Expect = 0.63
Identities = 54/241 (22%), Positives = 87/241 (36%), Gaps = 23/241 (9%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
+++L + D G Y C A G LTVM P G L G ++
Sbjct: 2266 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2324
Query: 168 LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
L A G P ++W G+A + N T R++ R+A + C+
Sbjct: 2325 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 2369
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
++S + VQ P + G G ++ + + L C +A P P +H
Sbjct: 2370 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2427
Query: 284 TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSP 342
+ + R F + ++ + +G Y C A N G+ S V I P S
Sbjct: 2428 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 2487
Query: 343 P 343
P
Sbjct: 2488 P 2488
Score = 32.0 bits (71), Expect = 1.4
Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ + E+ G Y C+ A+ G L V+ P I G L + +
Sbjct: 1615 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 1671
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227
V+ A G P +SW L+ + +P V + V + E A S C+
Sbjct: 1672 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 1726
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287
++ TL VQ P + + + V L C A+P E W +
Sbjct: 1727 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 1785
Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
+L G E TL G S +G Y CEA N G V++++
Sbjct: 1786 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 1834
Score = 31.2 bits (69), Expect = 2.4
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 19/123 (15%)
Query: 264 DVKLTCKADAN------PPATEYHWTTLNGSLP----KGVEAQNRTLFFKGPINYSLAGT 313
DV LT +A P + W S P GV F ++ + +G
Sbjct: 12 DVALTVGLEAGGCGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGD 71
Query: 314 YICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGG 373
Y C+ATN +G+ S + ++ + PS E GR+A + G+AG L + G
Sbjct: 72 YECQATNEVGSTSRRAKLVVY---VPPSIREDGRKAN------VSGMAGQSLTLECDANG 122
Query: 374 IVV 376
V
Sbjct: 123 FPV 125
Score = 30.4 bits (67), Expect = 4.1
Identities = 53/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 120 GVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKP 179
G Y C A G + LTV A P ++ +V+RA +++VL+ A+G P
Sbjct: 2732 GRYTCS-ARNSAGVAHKHVFLTVQASPV--VKPLPSVVRAVA--EEEVLLPC--EASGIP 2784
Query: 180 PSVVSWETRLKGEAEYQEIRNPNGTVTVI---SRYRLVPSREAHQQSLACIVNYHMDRFK 236
++W+ + + G T + + R+ + + CI
Sbjct: 2785 RPTITWQK--------EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAM 2836
Query: 237 ESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPAT---EYHWTTLNGSLPKGV 293
L VQ P + G + L CKA +P + ++G+ K
Sbjct: 2837 GKTRLVVQVPPVIE-NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFT 2895
Query: 294 EAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFP-YTPSPPEHGRRAG 350
+ L K + AGTY C A N +G +V + I P +T P + R G
Sbjct: 2896 IQPSGELLVKN-LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLG 2952
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
R LR +G++ + R E +D G Y C A G + + L + + P +E
Sbjct: 3069 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3127
Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
+R+ G D VA A G+P + W
Sbjct: 3128 TVRS--GDD----VALRCQATGEPTPTIEW 3151
Score = 29.6 bits (65), Expect = 6.9
Identities = 13/45 (28%), Positives = 21/45 (46%)
Query: 300 LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPE 344
L + G + GTY CE +N +G S +++ + P P E
Sbjct: 1028 LLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 1072
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 57.0 bits (136), Expect = 4e-08
Identities = 72/280 (25%), Positives = 106/280 (37%), Gaps = 41/280 (14%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
++L R + D GVY C+ A+ G E L V PT IEG K + +
Sbjct: 1558 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 1614
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
C A G P +SW AE E R +G+V RL EA +C+
Sbjct: 1615 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 1668
Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ ++ VQ P++ + EG + ++L C+A +P T W N
Sbjct: 1669 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 1726
Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI--------- 333
G + GV+ A T + +G + C+ATN GT +VEV++
Sbjct: 1727 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVL 1786
Query: 334 --------------TEFPYTPSPPEH-GRRAGPVPTAIIG 358
+ FP PP H G A P P + G
Sbjct: 1787 EVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEG 1826
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+ + ++ D+G+Y C+ + G LTV PT T+ V + L
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 3142
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
V TC +G P V+W LK E +G V+ R +L + A + C+
Sbjct: 3143 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 3197
Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
++ + V P + G + L+ +V+L C+AD PP + W
Sbjct: 3198 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 3256
Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
L + + R +L KG + S AG Y C A NP G + VN+
Sbjct: 3257 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 3307
Score = 44.3 bits (103), Expect = 3e-04
Identities = 65/277 (23%), Positives = 113/277 (40%), Gaps = 36/277 (12%)
Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166
G++RL+++++ D G Y C A+ P G+ + L V P ++ VL+ G+
Sbjct: 1082 GSLRLAQVQVGDSGHYECT-ASNPAGSASHRYVLGVQVPPQ--VQPGPRVLKVLVGE--- 1135
Query: 167 VLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLAC 226
L C A G P +SW + + R P G+V + + + +A +
Sbjct: 1136 ALDLNCV-AEGNPEPQLSWSK----DGVVLQGRGPQGSV----HFAAIRTSDAGRYRCEA 1186
Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANPPATEYHWT 283
+ +D ++ + L V P + G L+R+ + L C A P + W
Sbjct: 1187 SNSAGVDAWE--VELRVLEPPHWGADETSG--LLERVAGENASLPCPARGTPKP-QVTWR 1241
Query: 284 TLNGSLP----KGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYT 339
S P GV F ++ + +G Y C+ATN +G+ S + ++ +
Sbjct: 1242 KGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVY---VP 1298
Query: 340 PSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVV 376
PS E GR+A + G+AG L + G V
Sbjct: 1299 PSIREDGRKAN------VSGMAGQSLTLECDANGFPV 1329
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 45/278 (16%)
Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
G +R++ ED G Y+C A G+ + L V P + EG+ A L
Sbjct: 4000 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 4058
Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
K A G P ++W+ + Q + G T+ L+
Sbjct: 4059 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 4098
Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
Q + C + R + + L + P T G+ L+ D + L C A +P
Sbjct: 4099 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 4156
Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
WT + + +GV Q+ + + ++ +GTY+C A N +G V++
Sbjct: 4157 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215
Query: 335 EFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVG 372
E P G + ++ V GSI L +V G
Sbjct: 4216 EAPVL---------QGEAFSYLVEPVGGSIQLDCVVRG 4244
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ +++L DEG+Y C AT G + ++ L V+ P N G K +
Sbjct: 1850 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 1902
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C
Sbjct: 1903 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 1956
Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ + + L V P +T+ L V+LTC A P T N
Sbjct: 1957 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 2016
Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323
P G F G +LA G Y C A + +G
Sbjct: 2017 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 2057
Score = 39.7 bits (91), Expect = 0.007
Identities = 54/220 (24%), Positives = 87/220 (39%), Gaps = 45/220 (20%)
Query: 151 EGTQ---AVLRAKKGQDDKVLVAT--------CTSANGKPPSVVSWETRLKGEAEYQEIR 199
EGT AV RA G+ +V T + P R+ GEA Y
Sbjct: 491 EGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYN--- 547
Query: 200 NPNGTVTVISRYRLVPSREAHQQSLA------------------CIVNYHMDRFKESLTL 241
+T + +R++P+ LA C+ + + S+ L
Sbjct: 548 -----LTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWL 602
Query: 242 NVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG----VEAQN 297
V+ P+V+I + Q ++VK++C A P W+ + +L + V+AQ
Sbjct: 603 LVREAPQVSIHT-SSQHFSQGVEVKVSCSASGYP-TPHISWSRESQALQEDSRIHVDAQG 660
Query: 298 RTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFP 337
TL +G + AG Y C+ATN +GT V + T+ P
Sbjct: 661 -TLIIQG-VAPEDAGNYSCQATNEVGTDQETVTLYYTDPP 698
Score = 38.5 bits (88), Expect = 0.015
Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
L + +L EG Y CE + GN L L V P I G + D V
Sbjct: 2222 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 2278
Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
C +A GKPP V+WE + G +++N ++ V ++ AH +C+
Sbjct: 2279 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 2331
Query: 229 NYHMDRFKESLTLNVQYEPEV 249
R + L+V PE+
Sbjct: 2332 ENLAGRAERKFELSVLVPPEL 2352
Score = 38.1 bits (87), Expect = 0.019
Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%)
Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
+ + + + V L C A+P P +VTW K + S+G V
Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 2984
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
FL P T++L R L D G+Y CE A G + + L+V+ P A
Sbjct: 2985 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 3030
Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+A +G D VLV A + P V+W + Q + G
Sbjct: 3031 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 3086
Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
R + ++ + + +C V+ + TL VQ P + + + LTC
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 3146
Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320
P T T L +P A + + G + S AGTY C A N
Sbjct: 3147 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199
Score = 37.0 bits (84), Expect = 0.043
Identities = 55/244 (22%), Positives = 86/244 (35%), Gaps = 21/244 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+R+ + +L D G Y C A+ G+ E + L V P + VL
Sbjct: 1941 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 1990
Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
V T +A G P + W LK P V R L +R +
Sbjct: 1991 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 2047
Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
+C+ + ++ + L V P + E + + + V L C++ A PP W
Sbjct: 2048 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 2106
Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPS 341
P+ GV + ++ L + AG Y CEA N G +N+ P P
Sbjct: 2107 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPL 2166
Query: 342 PPEH 345
H
Sbjct: 2167 RESH 2170
Score = 34.3 bits (77), Expect = 0.28
Identities = 60/266 (22%), Positives = 92/266 (34%), Gaps = 30/266 (11%)
Query: 105 TDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQD 164
+ G +R+ + D G Y C A G+ +++ L V P + R +
Sbjct: 746 SSGKLRIPAAQERDAGTYTCR-AVNELGDASAEIQLAVGHAPQ-----LTELPRDVTVEL 799
Query: 165 DKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSL 224
+ + C A G+PP V+W +G+ + +R G SR R S +S+
Sbjct: 800 GRSALLACR-ATGRPPPTVTWR---RGDGQPLGLRLGAGRG---SRSRQPDSGVLFFESV 852
Query: 225 A--------CIVNYHMDRFKESLTLNVQ-YEPEVTIEGFDGNWYLQRMDVKLTCKADANP 275
A C + + L V + P L+ V L C A
Sbjct: 853 APEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGR 912
Query: 276 PATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYICEATNPIGTRSGQVE 330
P E HW LP G R G ++ A G Y C ATN G++ VE
Sbjct: 913 PLPERHWLKDGRPLPPGSRHSIRA---DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVE 969
Query: 331 VNITEFPYTPSPPEHGRRAGPVPTAI 356
+ + P H VP ++
Sbjct: 970 LVVQVPPRIHPTATHHITNEGVPASL 995
Score = 34.3 bits (77), Expect = 0.28
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
T+R+S+++L D G++ C A P G + L V P VL + Q+D V
Sbjct: 3368 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 3417
Query: 168 -----LVATCTSANGKPPSVVSW 185
LV A G P +VSW
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSW 3440
Score = 34.3 bits (77), Expect = 0.28
Identities = 55/267 (20%), Positives = 87/267 (32%), Gaps = 38/267 (14%)
Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P
Sbjct: 3713 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 3767
Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+ L A + C ++ P VV W+ K + Q+
Sbjct: 3768 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 3811
Query: 210 RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
YRL+PS C+V+ + + V P + + D +
Sbjct: 3812 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 3871
Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
V LTC + P T W+ L G + G + A G Y C
Sbjct: 3872 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 3927
Query: 317 EATNPIGTRSGQVEVNITEFPYTPSPP 343
A N G V + + P P
Sbjct: 3928 SARNSAGVAHKHVFLTVQASPVVKPLP 3954
Score = 33.1 bits (74), Expect = 0.63
Identities = 54/241 (22%), Positives = 87/241 (36%), Gaps = 23/241 (9%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
+++L + D G Y C A G LTVM P G L G ++
Sbjct: 3457 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 3515
Query: 168 LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
L A G P ++W G+A + N T R++ R+A + C+
Sbjct: 3516 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 3560
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
++S + VQ P + G G ++ + + L C +A P P +H
Sbjct: 3561 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 3618
Query: 284 TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSP 342
+ + R F + ++ + +G Y C A N G+ S V I P S
Sbjct: 3619 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 3678
Query: 343 P 343
P
Sbjct: 3679 P 3679
Score = 32.3 bits (72), Expect = 1.1
Identities = 53/241 (21%), Positives = 87/241 (36%), Gaps = 36/241 (14%)
Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDK 166
G + + ED+ Y+CE A G +++ L V I + +R +GQ
Sbjct: 845 GVLFFESVAPEDQAPYVCE-ARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVS 903
Query: 167 VLVATCTSANGKPPSVVSW--ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSL 224
+ C G+P W + R IR +G++ L + + H
Sbjct: 904 L---PCIVLAGRPLPERHWLKDGRPLPPGSRHSIR-ADGSL------HLDRALQEHAGRY 953
Query: 225 ACIVNYHMDRFKESLTLNVQYEPEV--------TIEGFDGNWYLQRMDVKLTCKADANPP 276
+C+ + L VQ P + T EG + L C A + P
Sbjct: 954 SCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEG---------VPASLPCVA-SGVP 1003
Query: 277 ATEYHWTTLNGSL----PKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVN 332
A WT +L P ++ TL P AG Y+C ATN +G S ++ ++
Sbjct: 1004 APTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQD-AGAYVCTATNTVGFSSQEMRLS 1062
Query: 333 I 333
+
Sbjct: 1063 V 1063
Score = 32.0 bits (71), Expect = 1.4
Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ + E+ G Y C+ A+ G L V+ P I G L + +
Sbjct: 2806 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 2862
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227
V+ A G P +SW L+ + +P V + V + E A S C+
Sbjct: 2863 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 2917
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287
++ TL VQ P + + + V L C A+P E W +
Sbjct: 2918 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 2976
Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
+L G E TL G S +G Y CEA N G V++++
Sbjct: 2977 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 30.4 bits (67), Expect = 4.1
Identities = 53/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 120 GVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKP 179
G Y C A G + LTV A P ++ +V+RA +++VL+ A+G P
Sbjct: 3923 GRYTCS-ARNSAGVAHKHVFLTVQASPV--VKPLPSVVRAVA--EEEVLLPC--EASGIP 3975
Query: 180 PSVVSWETRLKGEAEYQEIRNPNGTVTVI---SRYRLVPSREAHQQSLACIVNYHMDRFK 236
++W+ + + G T + + R+ + + CI
Sbjct: 3976 RPTITWQK--------EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAM 4027
Query: 237 ESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPAT---EYHWTTLNGSLPKGV 293
L VQ P + G + L CKA +P + ++G+ K
Sbjct: 4028 GKTRLVVQVPPVIE-NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFT 4086
Query: 294 EAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFP-YTPSPPEHGRRAG 350
+ L K + AGTY C A N +G +V + I P +T P + R G
Sbjct: 4087 IQPSGELLVKN-LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLG 4143
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
R LR +G++ + R E +D G Y C A G + + L + + P +E
Sbjct: 4260 RGSHLRHQLQNGSLTIHRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 4318
Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
+R+ G D VA A G+P + W
Sbjct: 4319 TVRS--GDD----VALRCQATGEPTPTIEW 4342
Score = 29.6 bits (65), Expect = 6.9
Identities = 13/45 (28%), Positives = 21/45 (46%)
Query: 300 LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPE 344
L + G + GTY CE +N +G S +++ + P P E
Sbjct: 2219 LLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 2263
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 57.0 bits (136), Expect = 4e-08
Identities = 72/280 (25%), Positives = 106/280 (37%), Gaps = 41/280 (14%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
++L R + D GVY C+ A+ G E L V PT IEG K + +
Sbjct: 276 LQLGRAQSSDAGVYTCK-ASNAVGAAEKATRLDVYVPPT--IEGAGGRPYVVKAVAGRPV 332
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIR-NPNGTVTVISRYRLVPSREAHQQSLACI 227
C A G P +SW AE E R +G+V RL EA +C+
Sbjct: 333 ALECV-ARGHPSPTLSWHHEGLPVAESNESRLETDGSVL-----RLESPGEASSGLYSCV 386
Query: 228 VNYHMDRFKESLTLNVQYEPEVTI-EGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ ++ VQ P++ + EG + ++L C+A +P T W N
Sbjct: 387 ASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPT-IQWLQ-N 444
Query: 287 GSLPK---GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI--------- 333
G + GV+ A T + +G + C+ATN GT +VEV++
Sbjct: 445 GRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVL 504
Query: 334 --------------TEFPYTPSPPEH-GRRAGPVPTAIIG 358
+ FP PP H G A P P + G
Sbjct: 505 EVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEG 544
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/232 (24%), Positives = 91/232 (39%), Gaps = 19/232 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+ + ++ D+G+Y C+ + G LTV PT T+ V + L
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSP----L 1860
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
V TC +G P V+W LK E +G V+ R +L + A + C+
Sbjct: 1861 VLTC-DVSGVPAPTVTW---LKDRMPV-ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVA 1915
Query: 229 NYHMDRFKESLTLNVQYEPEVTIEGFDGNWY-LQRMDVKLTCKADANPPATEYHWTTLNG 287
++ + V P + G + L+ +V+L C+AD PP + W
Sbjct: 1916 ENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPP-PDVAWLKDGS 1974
Query: 288 SLPKGVEAQNR------TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
L + + R +L KG + S AG Y C A NP G + VN+
Sbjct: 1975 PLGQDMGPHLRFYLDGGSLVLKG-LRASDAGAYTCVAHNPAGEDARLHTVNV 2025
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/278 (21%), Positives = 102/278 (36%), Gaps = 45/278 (16%)
Query: 107 GTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPT--------NWIEGTQAVLR 158
G +R++ ED G Y+C A G+ + L V P + EG+ A L
Sbjct: 2718 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLP 2776
Query: 159 AKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE 218
K A G P ++W+ + Q + G T+ L+
Sbjct: 2777 CK--------------ARGSPEPNITWDK------DGQPVSGAEGKFTIQPSGELLVKNL 2816
Query: 219 AHQQS--LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMD-VKLTCKADANP 275
Q + C + R + + L + P T G+ L+ D + L C A +P
Sbjct: 2817 EGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTT--LPGDRSLRLGDRLWLRCAARGSP 2874
Query: 276 PATEYHWTTLNGSLPKGVEAQNR-TLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNIT 334
WT + + +GV Q+ + + ++ +GTY+C A N +G V++
Sbjct: 2875 -TPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 2933
Query: 335 EFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVG 372
E P G + ++ V GSI L +V G
Sbjct: 2934 EAPVL---------QGEAFSYLVEPVGGSIQLDCVVRG 2962
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/224 (25%), Positives = 88/224 (39%), Gaps = 25/224 (11%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ +++L DEG+Y C AT G + ++ L V+ P N G K +
Sbjct: 568 LQIEKVDLRDEGIYTCA-ATNLAGESKREVALKVLV-PPNIEPGP-----VNKAVLENAS 620
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNG-TVTVISR-YRLVPSREAHQQSLAC 226
V A+G PP VSW KG +Q + + G TV+V R R+ ++ + S C
Sbjct: 621 VTLECLASGVPPPDVSW---FKG---HQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRC 674
Query: 227 IVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLN 286
+ + + L V P +T+ L V+LTC A P T N
Sbjct: 675 VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGN 734
Query: 287 GSLPKGVEAQNRTLFFKGPINYSLA-------GTYICEATNPIG 323
P G F G +LA G Y C A + +G
Sbjct: 735 PVSPAGTPGLQ---VFPGGRVLTLASARASDSGRYSCVAVSAVG 775
Score = 38.5 bits (88), Expect = 0.015
Identities = 37/141 (26%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 111 LSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVA 170
L + +L EG Y CE + GN L L V P I G + D V
Sbjct: 940 LGQAQLAQEGTYTCECSNV-VGNSSQDLQLEVHVPPQ--IAGPREPPTQVSVVQDGVATL 996
Query: 171 TCTSANGKPPSVVSWET--RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIV 228
C +A GKPP V+WE + G +++N ++ V ++ AH +C+
Sbjct: 997 EC-NATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHV------ERAQAAHTGRYSCVA 1049
Query: 229 NYHMDRFKESLTLNVQYEPEV 249
R + L+V PE+
Sbjct: 1050 ENLAGRAERKFELSVLVPPEL 1070
Score = 38.1 bits (87), Expect = 0.019
Identities = 69/296 (23%), Positives = 105/296 (35%), Gaps = 53/296 (17%)
Query: 37 DSMYGFIGTDVVLHCSF-ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRE 95
+ + + + V L C A+P P +VTW K + S+G V
Sbjct: 1663 EQVTAILNSSVSLPCDVHAHPNP-----EVTWYKDSQAL---------SLGEEV------ 1702
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
FL P T++L R L D G+Y CE A G + + L+V+ P A
Sbjct: 1703 ---FLLPG--THTLQLGRARLSDSGMYTCE-ALNAAGRDQKLVQLSVLVPP--------A 1748
Query: 156 VLRAKKGQDDKVLVATCTSA------NGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+A +G D VLV A + P V+W + Q + G
Sbjct: 1749 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG----Q 1804
Query: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTC 269
R + ++ + + +C V+ + TL VQ P + + + LTC
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1864
Query: 270 KADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYS-----LAGTYICEATN 320
P T T L +P A + + G + S AGTY C A N
Sbjct: 1865 DVSGVPAPTV---TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917
Score = 37.0 bits (84), Expect = 0.043
Identities = 55/244 (22%), Positives = 86/244 (35%), Gaps = 21/244 (8%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+R+ + +L D G Y C A+ G+ E + L V P + VL
Sbjct: 659 LRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPR---------ITLPPSLPGPVL 708
Query: 169 VAT----CTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRY-RLVPSREAHQQS 223
V T +A G P + W LK P V R L +R +
Sbjct: 709 VNTPVRLTCNATGAPSPTLMW---LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR 765
Query: 224 LACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
+C+ + ++ + L V P + E + + + V L C++ A PP W
Sbjct: 766 YSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVS-VVANESVALECQSHAMPPPVLSWWK 824
Query: 284 TLNGSLPK-GVE-AQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPS 341
P+ GV + ++ L + AG Y CEA N G +N+ P P
Sbjct: 825 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPL 884
Query: 342 PPEH 345
H
Sbjct: 885 RESH 888
Score = 34.3 bits (77), Expect = 0.28
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 15/83 (18%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
T+R+S+++L D G++ C A P G + L V P VL + Q+D V
Sbjct: 2086 TLRISKVQLADAGIFTC-VAASPAGVADRNFTLQVQVPP---------VLEPVEFQNDVV 2135
Query: 168 -----LVATCTSANGKPPSVVSW 185
LV A G P +VSW
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSW 2158
Score = 34.3 bits (77), Expect = 0.28
Identities = 55/267 (20%), Positives = 87/267 (32%), Gaps = 38/267 (14%)
Query: 90 LAPYRERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNW 149
L P R E L +G++R+ + +D G Y+C A+ G+ +L V+ P
Sbjct: 2431 LDPRSPRFEIL----PEGSLRIQPVLAQDAGHYLC-LASNSAGSDRQGRDLRVLEPPAIA 2485
Query: 150 IEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVIS 209
+ L A + C ++ P VV W+ K + Q+
Sbjct: 2486 PSPSNLTLTAHTPA-----LLPCEASGSPKPLVVWWKDGQKLDFRLQQ-----------G 2529
Query: 210 RYRLVPSREA--------HQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQ 261
YRL+PS C+V+ + + V P + + D +
Sbjct: 2530 AYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMM 2589
Query: 262 RMDVKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLA-----GTYIC 316
V LTC + P T W+ L G + G + A G Y C
Sbjct: 2590 A-PVVLTCHSTGIPAPT-VSWSKAGAQL--GARGSGYRVSPSGALEIGQALPIHAGRYTC 2645
Query: 317 EATNPIGTRSGQVEVNITEFPYTPSPP 343
A N G V + + P P
Sbjct: 2646 SARNSAGVAHKHVFLTVQASPVVKPLP 2672
Score = 33.1 bits (74), Expect = 0.63
Identities = 54/241 (22%), Positives = 87/241 (36%), Gaps = 23/241 (9%)
Query: 108 TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKV 167
+++L + D G Y C A G LTVM P G L G ++
Sbjct: 2175 SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 2233
Query: 168 LVATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACI 227
L A G P ++W G+A + N T R++ R+A + C+
Sbjct: 2234 LC----DAQGTPQPNITWHK--DGQALTRLENNSRAT-------RVLRVRDAGLYT--CL 2278
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRM---DVKLTCKADANP-PATEYHWT 283
++S + VQ P + G G ++ + + L C +A P P +H
Sbjct: 2279 AESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD 2336
Query: 284 TLNGSLPKGVEAQNRTLFFK-GPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSP 342
+ + R F + ++ + +G Y C A N G+ S V I P S
Sbjct: 2337 GIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSG 2396
Query: 343 P 343
P
Sbjct: 2397 P 2397
Score = 32.0 bits (71), Expect = 1.4
Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 15/230 (6%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+++ + E+ G Y C+ A+ G L V+ P I G L + +
Sbjct: 1524 LQIPLVRAENAGRYSCK-ASNEVGEDWLHYELLVLTPPV--ILGDTEELVEEVTVNASST 1580
Query: 169 VATCTSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSRE-AHQQSLACI 227
V+ A G P +SW L+ + +P V + V + E A S C+
Sbjct: 1581 VSLQCPALGNPVPTISW---LQNGLPFSP--SPRLQVLEDGQVLQVSTAEVADAASYMCV 1635
Query: 228 VNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNG 287
++ TL VQ P + + + V L C A+P E W +
Sbjct: 1636 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNP-EVTWYKDSQ 1694
Query: 288 SLPKGVEA----QNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
+L G E TL G S +G Y CEA N G V++++
Sbjct: 1695 ALSLGEEVFLLPGTHTLQL-GRARLSDSGMYTCEALNAAGRDQKLVQLSV 1743
Score = 30.4 bits (67), Expect = 4.1
Identities = 53/238 (22%), Positives = 87/238 (36%), Gaps = 24/238 (10%)
Query: 120 GVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKP 179
G Y C A G + LTV A P ++ +V+RA +++VL+ A+G P
Sbjct: 2641 GRYTCS-ARNSAGVAHKHVFLTVQASPV--VKPLPSVVRAVA--EEEVLLPC--EASGIP 2693
Query: 180 PSVVSWETRLKGEAEYQEIRNPNGTVTVI---SRYRLVPSREAHQQSLACIVNYHMDRFK 236
++W+ + + G T + + R+ + + CI
Sbjct: 2694 RPTITWQK--------EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAM 2745
Query: 237 ESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPAT---EYHWTTLNGSLPKGV 293
L VQ P + G + L CKA +P + ++G+ K
Sbjct: 2746 GKTRLVVQVPPVIE-NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFT 2804
Query: 294 EAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFP-YTPSPPEHGRRAG 350
+ L K + AGTY C A N +G +V + I P +T P + R G
Sbjct: 2805 IQPSGELLVKN-LEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLG 2861
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQA 155
R LR +G++ + R E +D G Y C A G + + L + + P +E
Sbjct: 2978 RGSHLRHQLQNGSLTIRRTERDDAGRYQC-LAENEMGVAKKVVILVLQSAPVFQVEPQDM 3036
Query: 156 VLRAKKGQDDKVLVATCTSANGKPPSVVSW 185
+R+ G D VA A G+P + W
Sbjct: 3037 TVRS--GDD----VALRCQATGEPTPTIEW 3060
Score = 29.6 bits (65), Expect = 6.9
Identities = 13/45 (28%), Positives = 21/45 (46%)
Query: 300 LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPE 344
L + G + GTY CE +N +G S +++ + P P E
Sbjct: 937 LLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 981
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 56.6 bits (135), Expect = 5e-08
Identities = 79/323 (24%), Positives = 115/323 (35%), Gaps = 35/323 (10%)
Query: 54 ANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSR 113
+NP+ T + T + I N S+ VS L+ S + T+ L
Sbjct: 154 SNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPR---------LQLSNGNRTLTLLS 204
Query: 114 LELEDEGVYICEFATFPTGNRESQLNLTVMAKP-TNWIEGTQAVLRAKKGQDDKVLVATC 172
+ D G Y CE + NR + L V P T I + R L +C
Sbjct: 205 VTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGAN-----LSLSC 259
Query: 173 TSANGKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM 232
+A+ PP+ SW + QE+ PN TV Y + + + +
Sbjct: 260 YAASN-PPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIV 318
Query: 233 DRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
+ + T+ G + V LTC N W N SLP
Sbjct: 319 TELSPVVAKPQIKASKTTVTG-------DKDSVNLTCST--NDTGISIRWFFKNQSLPSS 369
Query: 293 VE---AQNRTLFFKGPINYSLAGTYICEATNPIG-TRSGQVEVNITEFPYTPSPPEHGRR 348
+Q T P+ AGTY CE NPI +S + +N+ Y P E+G
Sbjct: 370 ERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVN---YNALPQENGLS 426
Query: 349 AGPVPTAIIGGVAGSILLVLIVV 371
G + +IG VA L+ LI V
Sbjct: 427 PGAIAGIVIGVVA---LVALIAV 446
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 53.1 bits (126), Expect = 6e-07
Identities = 60/247 (24%), Positives = 98/247 (39%), Gaps = 22/247 (8%)
Query: 15 GLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGS 74
G ALG F L G +V D + +GTD L CSF +P P + Q+ +
Sbjct: 15 GAALGALWFCLTGA-LEVQVPEDPVVALVGTDATLCCSF-SPEPGFSLAQLNLIWQLTDT 72
Query: 75 KQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDG--TIRLSRLELEDEGVYICEFATFPTG 132
KQ +++ + G + Y R G ++RL R+ + DEG + C + G
Sbjct: 73 KQ--LVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFG 130
Query: 133 NRESQLNLTV-MAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWE----T 187
+ L + +KP+ +E K + + TC+S G P + V W+
Sbjct: 131 SAAVSLQVAAPYSKPSMTLEPN------KDLRPGDTVTITCSSYQGYPEAEVFWQDGQGV 184
Query: 188 RLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKESLTLNVQY 245
L G ++ N G V S R+V + +C+V + S+T+ Q
Sbjct: 185 PLTGNVTTSQMANEQGLFDVHSILRVVLGANG---TYSCLVRNPVLQQDAHSSVTITPQR 241
Query: 246 EPEVTIE 252
P +E
Sbjct: 242 SPTGAVE 248
Score = 48.9 bits (115), Expect = 1e-05
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 17/190 (8%)
Query: 33 VQV-NDSMYGFIGTDVVLHCSFANPLPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLA 91
VQV D + +GTD L CSF +P P + Q+ +KQ +++ + G +
Sbjct: 249 VQVPEDPVVALVGTDATLRCSF-SPEPGFSLAQLNLIWQLTDTKQ--LVHSFTEGRDQGS 305
Query: 92 PYRERVEFLRPSFTDG--TIRLSRLELEDEGVYICEFATFPTGNRESQLNLTV-MAKPTN 148
Y R G ++RL R+ + DEG + C + G+ L + +KP+
Sbjct: 306 AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSM 365
Query: 149 WIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSWE----TRLKGEAEYQEIRNPNGT 204
+E K + + TC+S G P + V W+ L G ++ N G
Sbjct: 366 TLEPN------KDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGL 419
Query: 205 VTVISRYRLV 214
V S R+V
Sbjct: 420 FDVHSVLRVV 429
Score = 32.7 bits (73), Expect = 0.82
Identities = 56/227 (24%), Positives = 91/227 (40%), Gaps = 36/227 (15%)
Query: 212 RLVPSREAHQQSLACIVNYHMDRFKESLTLNVQY---EPEVTIEGFDGNWYLQRMD-VKL 267
RL R A + S C V+ D +++L V +P +T+E N L+ D V +
Sbjct: 326 RLQRVRVADEGSFTCFVSIR-DFGSAAVSLQVAAPYSKPSMTLEP---NKDLRPGDTVTI 381
Query: 268 TCKADANPPATEYHW-----TTLNGSLPKGVEAQNRTLFFKGPINYSLAG---TYICEAT 319
TC + P E W L G++ A + LF + + G TY C
Sbjct: 382 TCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVR 441
Query: 320 NPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALR 379
NP+ + V IT P T PPE A+ V S+ L+ ++V V R
Sbjct: 442 NPVLQQDAHGSVTITGQPMT-FPPE----------ALWVTVGLSVCLIALLVALAFVCWR 490
Query: 380 RRRHTFKGDYSTKKHVYGNGY-SKAGIPQHHPPMAQNLQYPDDSDDE 425
+ + + + + + + G G SK + Q L++ D +D+
Sbjct: 491 KIKQSCEEENAGAEDQDGEGEGSKTAL--------QPLKHSDSKEDD 529
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 53.1 bits (126), Expect = 6e-07
Identities = 53/234 (22%), Positives = 96/234 (41%), Gaps = 23/234 (9%)
Query: 109 IRLSRLELEDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVL 168
+ ++ EL D+ Y C+ +R ++L + + + T G +L+A +
Sbjct: 85 LEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHN---- 140
Query: 169 VATCTSANGKPPSVVSW---ETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLA 225
TC + N KP + + W T+ +G E+ T +S+ + P+ +
Sbjct: 141 -LTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFT 199
Query: 226 C-IVNYHMDRFKE-SLTLNVQYEPEVTIEGFDGNWYLQRMDVKLTCKADANPPATEYHWT 283
C +N + KE S+ L+V + P VT+ + + V TC+A ANP Y W
Sbjct: 200 CRSMNEAIPSGKETSIELDVHHPPTVTLS-IEPQTVQEGERVVFTCQATANPEILGYRWA 258
Query: 284 TLNGSLPKGVEAQNRT----LFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
+ E++ T FF P++ CE N +G+ + VN+
Sbjct: 259 KGGFLIEDAHESRYETNVDYSFFTEPVS--------CEVHNKVGSTNVSTLVNV 304
Score = 37.0 bits (84), Expect = 0.043
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 7/134 (5%)
Query: 209 SRYRLVPSREAHQQSLACIVNYHMDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDVKLT 268
SRY + ++C V+ + S +NV + P + ++ + DV LT
Sbjct: 270 SRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGS-DVTLT 328
Query: 269 CKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNP-IGTRSG 327
C NPP T WT + ++ V + + L K + + AGTY C A P IG
Sbjct: 329 CVWVGNPPLT-LTWTKKDSNM---VLSNSNQLLLKS-VTQADAGTYTCRAIVPRIGVAER 383
Query: 328 QVEVNITEFPYTPS 341
+V + + P S
Sbjct: 384 EVPLYVNGPPIISS 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,157,396
Number of Sequences: 37866
Number of extensions: 1129832
Number of successful extensions: 6332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 297
Number of HSP's that attempted gapping in prelim test: 5243
Number of HSP's gapped (non-prelim): 1114
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.