BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] (2416 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 4852 0.0 gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 4561 0.0 gi|38372931 brevican isoform 2 [Homo sapiens] 369 e-101 gi|38372935 brevican isoform 1 [Homo sapiens] 369 e-101 gi|21361116 versican isoform 1 [Homo sapiens] 363 1e-99 gi|187607300 versican isoform 2 [Homo sapiens] 361 5e-99 gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 328 5e-89 gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sap... 224 6e-58 gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo sapi... 212 3e-54 gi|11141887 brain link protein-1 [Homo sapiens] 189 2e-47 gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sap... 189 2e-47 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 149 4e-35 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 142 5e-33 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 142 5e-33 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 142 5e-33 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 133 2e-30 gi|167736355 mucin 4 isoform a [Homo sapiens] 128 8e-29 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 127 1e-28 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 125 4e-28 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 125 4e-28 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 124 1e-27 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 124 1e-27 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 124 1e-27 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 124 1e-27 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 121 9e-27 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 119 3e-26 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 119 5e-26 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 118 8e-26 gi|110624774 mannose receptor, C type 2 [Homo sapiens] 117 2e-25 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 116 2e-25 >gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] Length = 2416 Score = 4852 bits (12586), Expect = 0.0 Identities = 2416/2416 (100%), Positives = 2416/2416 (100%) Query: 1 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV Sbjct: 1 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60 Query: 61 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV Sbjct: 61 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120 Query: 121 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA Sbjct: 121 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180 Query: 181 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE Sbjct: 181 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240 Query: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG Sbjct: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300 Query: 301 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN Sbjct: 301 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360 Query: 361 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF Sbjct: 361 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420 Query: 421 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF Sbjct: 421 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480 Query: 481 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS Sbjct: 481 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540 Query: 541 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES Sbjct: 541 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600 Query: 601 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT Sbjct: 601 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660 Query: 661 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA Sbjct: 661 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720 Query: 721 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV Sbjct: 721 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780 Query: 781 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE Sbjct: 781 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840 Query: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD Sbjct: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 Query: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG Sbjct: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960 Query: 961 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL Sbjct: 961 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020 Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT Sbjct: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 Query: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG Sbjct: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140 Query: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED Sbjct: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200 Query: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG Sbjct: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260 Query: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS Sbjct: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320 Query: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE Sbjct: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380 Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG Sbjct: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL Sbjct: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500 Query: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST Sbjct: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560 Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG Sbjct: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620 Query: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD Sbjct: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680 Query: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE Sbjct: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740 Query: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG Sbjct: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800 Query: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM Sbjct: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860 Query: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV Sbjct: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920 Query: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS Sbjct: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980 Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL Sbjct: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS Sbjct: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100 Query: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES Sbjct: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160 Query: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH Sbjct: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220 Query: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH Sbjct: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280 Query: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE 2340 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE Sbjct: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE 2340 Query: 2341 HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ 2400 HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ Sbjct: 2341 HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ 2400 Query: 2401 KRSSRHPRRSRPSTAH 2416 KRSSRHPRRSRPSTAH Sbjct: 2401 KRSSRHPRRSRPSTAH 2416 >gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] Length = 2317 Score = 4561 bits (11831), Expect = 0.0 Identities = 2292/2330 (98%), Positives = 2292/2330 (98%), Gaps = 38/2330 (1%) Query: 1 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV Sbjct: 1 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60 Query: 61 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV Sbjct: 61 TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120 Query: 121 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA Sbjct: 121 QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180 Query: 181 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE Sbjct: 181 IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240 Query: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG Sbjct: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300 Query: 301 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN Sbjct: 301 WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360 Query: 361 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF Sbjct: 361 FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420 Query: 421 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF Sbjct: 421 APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480 Query: 481 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS Sbjct: 481 HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540 Query: 541 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES Sbjct: 541 PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600 Query: 601 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT Sbjct: 601 HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660 Query: 661 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA Sbjct: 661 GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720 Query: 721 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV Sbjct: 721 VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780 Query: 781 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE Sbjct: 781 PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840 Query: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD Sbjct: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 Query: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG Sbjct: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960 Query: 961 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL Sbjct: 961 EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020 Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT Sbjct: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 Query: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG Sbjct: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140 Query: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED Sbjct: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200 Query: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG Sbjct: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260 Query: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS Sbjct: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320 Query: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE Sbjct: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380 Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG Sbjct: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL Sbjct: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500 Query: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST Sbjct: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560 Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG Sbjct: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620 Query: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD Sbjct: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680 Query: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE Sbjct: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740 Query: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG Sbjct: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800 Query: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM Sbjct: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860 Query: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV Sbjct: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920 Query: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS Sbjct: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980 Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL Sbjct: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS Sbjct: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100 Query: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES Sbjct: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160 Query: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220 TAA DQEVCEEGWNKYQGHCYRH Sbjct: 2161 TAA--------------------------------------DQEVCEEGWNKYQGHCYRH 2182 Query: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH Sbjct: 2183 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2242 Query: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT 2330 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT Sbjct: 2243 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT 2292 >gi|38372931 brevican isoform 2 [Homo sapiens] Length = 671 Score = 369 bits (946), Expect = e-101 Identities = 205/435 (47%), Positives = 265/435 (60%), Gaps = 28/435 (6%) Query: 23 SDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTTAPSTAPL--APRIKWSRVSK 80 S D + V I +PL+ +LG +LTIPC+ +H + PS + +PR+KW+ +S+ Sbjct: 29 SSEDRAFRVRIAGDAPLQGVLGGALTIPCH----VHYLRPPPSRRAVLGSPRVKWTFLSR 84 Query: 81 EKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIE 140 +E +LVA RV+VN AY+ +V+LP YPA +D +L + LR NDSG+YRCEV HGI+ Sbjct: 85 GREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGID 144 Query: 141 DSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCD 200 DS +EV VKG+VF YR S RY F AQ AC + A IATPEQL AAY G+ QCD Sbjct: 145 DSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCD 204 Query: 201 AGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATS 260 AGWL+DQTVRYPI TPRE CYGD D FPGVR YG+ D ++ YDVYC+AE++ GE+F Sbjct: 205 AGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDP 264 Query: 261 PEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGG 320 PEK T +EA C+ GA +ATTGQLY AW G+D CS GWLAD SVRYPI CGG Sbjct: 265 PEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGG 324 Query: 321 NLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD-IPE------NFFGVGGEEDITVQ 373 L GV+T+++ NQTG+P+ SR++ C+ IPE N G E + Sbjct: 325 GLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLE---AIV 381 Query: 374 TVTWPDMELPLPRNITEGEARGSVILTVKPIFE----VSPSPLEPEE------PFTFAPE 423 TVT EL LP+ TE E+RG++ PI E S +P +P E F Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSI--PIMEDGGGGSSTPEDPAEAPRTLLEFETQSM 439 Query: 424 IGATAFAEVENETGE 438 + T F+E E + E Sbjct: 440 VPPTGFSEEEGKALE 454 Score = 291 bits (745), Expect = 5e-78 Identities = 194/513 (37%), Positives = 250/513 (48%), Gaps = 56/513 (10%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF YR G RY+ +F AQ+AC R GA IA+PEQL AAY GYEQCDAGWL DQTVRY Sbjct: 156 GVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRY 215 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596 PI +PR C GD D PGVR YGV + YDVYC+ + L GE+F E+ T +EA Sbjct: 216 PIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARA 275 Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656 +C+ A +ATTGQLYAAW GLD C GWLADGS+RYPIVTP CGG PGV+T++L+ Sbjct: 276 YCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLF 335 Query: 657 PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPS--GVEEWI-VTQVVP------ 707 PNQTG P+ SR + +CFR SA PS E ++P+ G+E + VT+ + Sbjct: 336 PNQTGFPNKHSRFNVYCFRD-SAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQ 394 Query: 708 ---------GVAAVPVEEE------TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752 + ++P+ E+ T P+ +LEF T + P G S Sbjct: 395 EATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFET--------QSMVPPTGFS 446 Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF---PSV 809 G EE E EV + PSE+ P E S EP S+ Sbjct: 447 EEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESL 506 Query: 810 RPFPS-VELFPSEEPFPSKEPSPSEEPSASEEPY----TP------SPPVPSWTELPSSG 858 P+ L P P P E S P P TP SP + E G Sbjct: 507 SQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVG 566 Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQL-------SGDRASGLPSGDLDSSGLTSTVGSG 911 E +G P++SG G + +G + + L G R PS D+SG T+ G+ Sbjct: 567 EATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE--DNSGRTAPAGTS 624 Query: 912 LPVESGLPSGDEERIEWPSTPTVGELPSGAEIL 944 + + LP+ R P G G+ L Sbjct: 625 VQAQPVLPTDSASRGGVAVVPASGNSAQGSTAL 657 Score = 39.3 bits (90), Expect = 0.047 Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 33/184 (17%) Query: 1572 ISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDT 1631 +S G + LP+ S P+ L AS PD E V G P+ Sbjct: 486 LSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT----- 540 Query: 1632 SGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGF 1691 ET L+S P EA V GE +G P+LSG P G Sbjct: 541 --ETLPTPRERNLASPSPSTLVEAREV--------------GEATGGPELSGVPRGESEE 584 Query: 1692 SGATSGVPDLVSGTTSGSG---------ESSGITFVDTSLVE---VAPTTFKEEEGLGSV 1739 +G++ G P L+ T + G ++SG T + V+ V PT G+ V Sbjct: 585 TGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVV 644 Query: 1740 ELSG 1743 SG Sbjct: 645 PASG 648 Score = 34.7 bits (78), Expect = 1.2 Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 16/133 (12%) Query: 1978 EVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDL----SETTSAFHEANLERSSGL 2033 E ++ ES S+ A GAS P+ E S P + +ET E NL S Sbjct: 498 EPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSP- 556 Query: 2034 GVSGSTLTF--QEGEASAAPEVSGESTTTSDVGTEAPGLPS---ATPTASGDR--TEISG 2086 STL + GEA+ PE+SG S+ + G PS AT G R S Sbjct: 557 ----STLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE 612 Query: 2087 DLSGHTSQLGVVI 2099 D SG T+ G + Sbjct: 613 DNSGRTAPAGTSV 625 Score = 33.9 bits (76), Expect = 2.0 Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 17/155 (10%) Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563 QAP + L G S G S PP G PT +L + + S ++ Sbjct: 508 QAPARAVLQPGASPLPDGESEASRPPR--------VHGPPTETLPTPRERNLASPSPSTL 559 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASG-------SPDVSGE-I 1615 +E R +G E+SG+P E + +G + G PS + G S D SG Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTA 619 Query: 1616 PGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPG 1650 P V QP P S GV + + G Sbjct: 620 PAGTSVQAQPV-LPTDSASRGGVAVVPASGNSAQG 653 Score = 32.3 bits (72), Expect = 5.8 Identities = 49/151 (32%), Positives = 67/151 (44%), Gaps = 25/151 (16%) Query: 1097 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1156 E ++PG E + LP+ E AA E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1157 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1212 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1213 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1241 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 Score = 32.0 bits (71), Expect = 7.6 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 25/151 (16%) Query: 1059 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1118 E ++PG E + LP+ + E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1119 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1174 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1175 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1203 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 Score = 32.0 bits (71), Expect = 7.6 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 11/114 (9%) Query: 1371 EDISGLPSGEVVETSASGIEDVSELPS------GEGLETSASGVEDLSRLPSGEEVLEI- 1423 E +S P+ V++ AS + D S G ET + E PS ++E Sbjct: 504 ESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAR 563 Query: 1424 ---SASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSG 1474 A+G +LSG+P G E ET +SE L EG + +ED SG Sbjct: 564 EVGEATGGPELSGVPRG-ESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSG 616 Score = 31.6 bits (70), Expect = 9.9 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 28/162 (17%) Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289 E ++PG E + LP+ E AA E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1290 APGVE--EISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347 P V LP+ +P + + + EV E T G E+SG+P GE ET + Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGEAT--GGPELSGVPRGESEETGS 587 Query: 1348 S----AVGDLSGLPSGGEVLEISVSGVEDISG--LPSGEVVE 1383 S ++ + P G LE + ED SG P+G V+ Sbjct: 588 SEGAPSLLPATRAPEGTRELE---APSEDNSGRTAPAGTSVQ 626 Score = 31.6 bits (70), Expect = 9.9 Identities = 47/151 (31%), Positives = 66/151 (43%), Gaps = 25/151 (16%) Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 E ++PG E + LP+ + E +S P+ VL+ PG S LP GE + Sbjct: 485 ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQ---PGA---SPLPDGESEASR 531 Query: 1081 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1136 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1137 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1165 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 Score = 31.6 bits (70), Expect = 9.9 Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 28/181 (15%) Query: 1281 PSGEVLETTAPGVEE--ISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLP 1338 P E T P +E +S P+ VL+ PG S LP GE + P V P Sbjct: 489 PGPEASLPTEPAAQEESLSQAPARAVLQ---PGA---SPLPDGESEASRPPRVHG----P 538 Query: 1339 SGEVLETSTS---AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSAS----GIED 1391 E L T A S L EV E +G ++SG+P GE ET +S + Sbjct: 539 PTETLPTPRERNLASPSPSTLVEAREVGE--ATGGPELSGVPRGESEETGSSEGAPSLLP 596 Query: 1392 VSELPSGEGLETSASGVEDLSR-LPSG-----EEVLEISASGFGDLSGLPSGGEGLETSA 1445 + P G E A ++ R P+G + VL ++ G ++ +P+ G + S Sbjct: 597 ATRAPEGT-RELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGNSAQGST 655 Query: 1446 S 1446 + Sbjct: 656 A 656 >gi|38372935 brevican isoform 1 [Homo sapiens] Length = 911 Score = 369 bits (946), Expect = e-101 Identities = 205/435 (47%), Positives = 265/435 (60%), Gaps = 28/435 (6%) Query: 23 SDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTTAPSTAPL--APRIKWSRVSK 80 S D + V I +PL+ +LG +LTIPC+ +H + PS + +PR+KW+ +S+ Sbjct: 29 SSEDRAFRVRIAGDAPLQGVLGGALTIPCH----VHYLRPPPSRRAVLGSPRVKWTFLSR 84 Query: 81 EKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIE 140 +E +LVA RV+VN AY+ +V+LP YPA +D +L + LR NDSG+YRCEV HGI+ Sbjct: 85 GREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGID 144 Query: 141 DSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCD 200 DS +EV VKG+VF YR S RY F AQ AC + A IATPEQL AAY G+ QCD Sbjct: 145 DSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCD 204 Query: 201 AGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATS 260 AGWL+DQTVRYPI TPRE CYGD D FPGVR YG+ D ++ YDVYC+AE++ GE+F Sbjct: 205 AGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDP 264 Query: 261 PEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGG 320 PEK T +EA C+ GA +ATTGQLY AW G+D CS GWLAD SVRYPI CGG Sbjct: 265 PEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGG 324 Query: 321 NLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD-IPE------NFFGVGGEEDITVQ 373 L GV+T+++ NQTG+P+ SR++ C+ IPE N G E + Sbjct: 325 GLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLE---AIV 381 Query: 374 TVTWPDMELPLPRNITEGEARGSVILTVKPIFE----VSPSPLEPEE------PFTFAPE 423 TVT EL LP+ TE E+RG++ PI E S +P +P E F Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSI--PIMEDGGGGSSTPEDPAEAPRTLLEFETQSM 439 Query: 424 IGATAFAEVENETGE 438 + T F+E E + E Sbjct: 440 VPPTGFSEEEGKALE 454 Score = 325 bits (834), Expect = 3e-88 Identities = 203/555 (36%), Positives = 276/555 (49%), Gaps = 52/555 (9%) Query: 1894 FASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLF 1953 F + S + S AS E + +E +E + P + E R + P + Sbjct: 353 FRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIME 412 Query: 1954 ESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSA--------YPEAGFGASAAPEA 2005 + G ST D + A L + P SE Y + E Sbjct: 413 DGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEE 472 Query: 2006 SRED-----------SGSPDLS-ETTSAFHEANLERSSGLGV---SGSTLTFQEGEASAA 2050 ED S P+ S T A E +L ++ V S L E EAS Sbjct: 473 EVEDEALWAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRP 532 Query: 2051 PEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQ 2110 P V G T T E L S +P+ + E+ G+ +G GV ESE T Sbjct: 533 PRVHGPPTETLPTPRER-NLASPSPSTLVEAREV-GEATGGPELSGVPRG----ESEETG 586 Query: 2111 QTQ---------RPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES- 2160 ++ R E E+E+ S SG T+P S+ A P +S S Sbjct: 587 SSEGAPSLLPATRAPEGTRELEAPSEDNSGR--------TAPAGTSVQAQPVLPTDSASR 638 Query: 2161 --TAAAPARS-CAEEPC-GAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGH 2216 A PA C PC GTC E E V CLC PGY G+ C++ C GW+ +QG Sbjct: 639 GGVAVVPASGDCVPSPCHNGGTCLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGA 698 Query: 2217 CYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRW 2276 CY+HF R +W +AE +CR +HL+SI TPEEQ+F+NN ++YQWIGLNDRTIEGDF W Sbjct: 699 CYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLW 758 Query: 2277 SDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2336 SDG P+ +ENW P QPD++F +GE+CVVM+WH++G+W+DVPCNYHL +TCK G V+CG P Sbjct: 759 SDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPP 818 Query: 2337 PVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYK 2396 P + A+ FG+ + RYE+++++RY+C EG QR++P IRCQ +G WE PQI+C P Sbjct: 819 PELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPLIRCQENGRWEAPQISCV-PRRPA 877 Query: 2397 RRLQKRSSRHPRRSR 2411 R L R+ R Sbjct: 878 RALHPEEDPEGRQGR 892 Score = 290 bits (741), Expect = 2e-77 Identities = 192/505 (38%), Positives = 248/505 (49%), Gaps = 56/505 (11%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF YR G RY+ +F AQ+AC R GA IA+PEQL AAY GYEQCDAGWL DQTVRY Sbjct: 156 GVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRY 215 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596 PI +PR C GD D PGVR YGV + YDVYC+ + L GE+F E+ T +EA Sbjct: 216 PIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARA 275 Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656 +C+ A +ATTGQLYAAW GLD C GWLADGS+RYPIVTP CGG PGV+T++L+ Sbjct: 276 YCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLF 335 Query: 657 PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPS--GVEEWI-VTQVVP------ 707 PNQTG P+ SR + +CFR SA PS E ++P+ G+E + VT+ + Sbjct: 336 PNQTGFPNKHSRFNVYCFRD-SAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQ 394 Query: 708 ---------GVAAVPVEEE------TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752 + ++P+ E+ T P+ +LEF T + P G S Sbjct: 395 EATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFET--------QSMVPPTGFS 446 Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF---PSV 809 G EE E EV + PSE+ P E S EP S+ Sbjct: 447 EEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESL 506 Query: 810 RPFPS-VELFPSEEPFPSKEPSPSEEPSASEEPY----TP------SPPVPSWTELPSSG 858 P+ L P P P E S P P TP SP + E G Sbjct: 507 SQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVG 566 Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQL-------SGDRASGLPSGDLDSSGLTSTVGSG 911 E +G P++SG G + +G + + L G R PS D+SG T+ G+ Sbjct: 567 EATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE--DNSGRTAPAGTS 624 Query: 912 LPVESGLPSGDEERIEWPSTPTVGE 936 + + LP+ R P G+ Sbjct: 625 VQAQPVLPTDSASRGGVAVVPASGD 649 Score = 39.3 bits (90), Expect = 0.047 Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 33/184 (17%) Query: 1572 ISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDT 1631 +S G + LP+ S P+ L AS PD E V G P+ Sbjct: 486 LSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT----- 540 Query: 1632 SGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGF 1691 ET L+S P EA V GE +G P+LSG P G Sbjct: 541 --ETLPTPRERNLASPSPSTLVEAREV--------------GEATGGPELSGVPRGESEE 584 Query: 1692 SGATSGVPDLVSGTTSGSG---------ESSGITFVDTSLVE---VAPTTFKEEEGLGSV 1739 +G++ G P L+ T + G ++SG T + V+ V PT G+ V Sbjct: 585 TGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVV 644 Query: 1740 ELSG 1743 SG Sbjct: 645 PASG 648 Score = 33.5 bits (75), Expect = 2.6 Identities = 40/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%) Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563 QAP + L G S G S PP G PT +L + + S ++ Sbjct: 508 QAPARAVLQPGASPLPDGESEASRPPR--------VHGPPTETLPTPRERNLASPSPSTL 559 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASG-------SPDVSGE-I 1615 +E R +G E+SG+P E + +G + G PS + G S D SG Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTA 619 Query: 1616 PGLFGVSGQPSGFPDTSGETSGV 1638 P V QP P S GV Sbjct: 620 PAGTSVQAQPV-LPTDSASRGGV 641 Score = 32.7 bits (73), Expect = 4.4 Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 28/187 (14%) Query: 1281 PSGEVLETTAPGVEE--ISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLP 1338 P E T P +E +S P+ VL+ PG S LP GE + P V P Sbjct: 489 PGPEASLPTEPAAQEESLSQAPARAVLQ---PGA---SPLPDGESEASRPPRVHG----P 538 Query: 1339 SGEVLETSTS---AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSAS----GIED 1391 E L T A S L EV E +G ++SG+P GE ET +S + Sbjct: 539 PTETLPTPRERNLASPSPSTLVEAREVGE--ATGGPELSGVPRGESEETGSSEGAPSLLP 596 Query: 1392 VSELPSGEGLETSASGVEDLSR-LPSG-----EEVLEISASGFGDLSGLPSGGEGLETSA 1445 + P G E A ++ R P+G + VL ++ G ++ +P+ G+ + + Sbjct: 597 ATRAPEGT-RELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPC 655 Query: 1446 SEVGTDL 1452 GT L Sbjct: 656 HNGGTCL 662 Score = 32.3 bits (72), Expect = 5.8 Identities = 49/151 (32%), Positives = 67/151 (44%), Gaps = 25/151 (16%) Query: 1097 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1156 E ++PG E + LP+ E AA E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1157 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1212 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1213 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1241 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 Score = 32.0 bits (71), Expect = 7.6 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 25/151 (16%) Query: 1059 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1118 E ++PG E + LP+ + E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1119 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1174 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1175 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1203 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 Score = 32.0 bits (71), Expect = 7.6 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 11/114 (9%) Query: 1371 EDISGLPSGEVVETSASGIEDVSELPS------GEGLETSASGVEDLSRLPSGEEVLEI- 1423 E +S P+ V++ AS + D S G ET + E PS ++E Sbjct: 504 ESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAR 563 Query: 1424 ---SASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSG 1474 A+G +LSG+P G E ET +SE L EG + +ED SG Sbjct: 564 EVGEATGGPELSGVPRG-ESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSG 616 Score = 31.6 bits (70), Expect = 9.9 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 28/162 (17%) Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289 E ++PG E + LP+ E AA E +S P+ VL+ A S LP GE + Sbjct: 485 ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531 Query: 1290 APGVE--EISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347 P V LP+ +P + + + EV E T G E+SG+P GE ET + Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGEAT--GGPELSGVPRGESEETGS 587 Query: 1348 S----AVGDLSGLPSGGEVLEISVSGVEDISG--LPSGEVVE 1383 S ++ + P G LE + ED SG P+G V+ Sbjct: 588 SEGAPSLLPATRAPEGTRELE---APSEDNSGRTAPAGTSVQ 626 Score = 31.6 bits (70), Expect = 9.9 Identities = 47/151 (31%), Positives = 66/151 (43%), Gaps = 25/151 (16%) Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080 E ++PG E + LP+ + E +S P+ VL+ PG S LP GE + Sbjct: 485 ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQ---PGA---SPLPDGESEASR 531 Query: 1081 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1136 P V LP+ A+P + + + EV E A G ++SG+P GE ET Sbjct: 532 PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587 Query: 1137 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1165 AP + + P G E AP ED SG Sbjct: 588 SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616 >gi|21361116 versican isoform 1 [Homo sapiens] Length = 3396 Score = 363 bits (932), Expect = 1e-99 Identities = 346/1212 (28%), Positives = 539/1212 (44%), Gaps = 172/1212 (14%) Query: 3 TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62 ++LW+ TL ++T A+ V + + P+R L +++PC+F M + Sbjct: 7 SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54 Query: 63 APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116 + +T+ RIKWS++ +K E +LVA G +++ Y+ +VS+P +P DA Sbjct: 55 SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113 Query: 117 TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176 +L V L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL Sbjct: 114 SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173 Query: 177 QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236 A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI PR GCYGDK GVRTYG R Sbjct: 174 DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233 Query: 237 DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296 ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC ARLAT G+L AW+ G D Sbjct: 234 SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293 Query: 297 CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD 356 C GWL+D SVR+P++ AR CGG LLGVRT+Y NQTG+P P SR+DA C+ ++ Sbjct: 294 CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATT 353 Query: 357 IPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEP-- 414 I D+++ T P+ +++ R + I+ + V P+ P Sbjct: 354 I-----------DLSILAETASPSLSKEPQMVSD---RTTPIIPLVDELPVIPTEFPPVG 399 Query: 415 -----EEPFTFAPEIGATAFA-EVENETGEATRPW---GFPTPGLGPATAFTSEDLVVQV 465 E+ T P+ + A ++ TG +PW + GP ++ +V Sbjct: 400 NIVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEV 459 Query: 466 -TAVPGQPHLP----GGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAG 520 + G H GVV T+ S+T Q + G ++ S E L+ Sbjct: 460 LQSTTGVSHYATDSWDGVV---EDKQTQESVT----QIEQIEVGPLVTSMEILKHIPSKE 512 Query: 521 YEQCD-----AGWLRDQTVRYPIVSPRTPCV---------GDKDSSPGVRTYGVRPSTET 566 + + A + + +VS + V G++D T G ST Sbjct: 513 FPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLI 572 Query: 567 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATT--------GQLYAAWSRG 618 +D EV ++ + T LE ES +A+ + G W Sbjct: 573 FDQI-------PEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWE-- 623 Query: 619 LDKCYAGWLADGSL-RYPIVTPRPA----------CGGDK---PGVRTVYLYPN-QTGLP 663 ++ +G + + L +Y TP P+ GDK G+ TV +YP+ QT + Sbjct: 624 -ERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTV-IYPSLQTEMT 681 Query: 664 DPLSRHHAFC--FRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAV 721 R R + EE +P EE + + P+ ++V Sbjct: 682 HRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSV 741 Query: 722 PSGET----TAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSA 777 ++ T I + + EP + E +T PG T T G + Sbjct: 742 EMTKSFDFPTLITKLSAEPTEVRDMEEDFTAT-----PG--TTKYDENITTVLLAHGTLS 794 Query: 778 TEVPSAS----EEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSE 833 E + S +E + + P S EPS S + P++ +V + ++ PS ++ Sbjct: 795 VEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPAL--LTTVGMNGKDKDIPSFTEDGAD 852 Query: 834 EPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASG 893 E +T +P S ++ +V+ + D++ H F+ + ++G Sbjct: 853 E----------------FTLIPDSTQKQ-LEEVTDE-----DIAAHGKFTIRFQPTTSTG 890 Query: 894 LPSGDL--DSS------GLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILE 945 + DS+ +TST G G G+ E ++ + V +P A E Sbjct: 891 IAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVD--LSKPVSTVPQFAHTSE 948 Query: 946 GSASGVGDLSGLPSGE-VLETSASGVGDLSGLPSGE--VLETTAPGVEDISGLPSGEVL- 1001 G+ +S + E +S LS +P + VL + P +++ G PS ++L Sbjct: 949 --VEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILV 1006 Query: 1002 -------ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL-- 1052 T +P + + G E P E + P + T E ++ L Sbjct: 1007 IDQTRLEATISPETMRTTKITEGTTQE-EFPWKEQTAEKPVPALSSTAWTPKEAVTPLDE 1065 Query: 1053 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-GLPSGEVLETAAPGVEDISGLPS 1111 G+ T E ++G VLETT G D S P G V E E ++ P Sbjct: 1066 QEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR 1125 Query: 1112 GEVLETAAPGVE 1123 + +PG E Sbjct: 1126 IGPKVSLSPGPE 1137 Score = 333 bits (853), Expect = 2e-90 Identities = 195/484 (40%), Positives = 251/484 (51%), Gaps = 52/484 (10%) Query: 1919 EVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVE 1978 E T I +F + T+ +S E + P TP+ +G V T D +E Sbjct: 2924 EGTEILQDF-QNKTDGQVSGEAIKMFPTIKTPE----AGTVITTAD-----------EIE 2967 Query: 1979 VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGS 2038 + + TSA G A P S + S P LS + E N E + L + G Sbjct: 2968 LEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSP----EINPETQAAL-IRGQ 3022 Query: 2039 TLTFQEGEASAAPEV--SGESTTTSDV--GTEAPGLPSATPTASGDRTEISGDLSGHTSQ 2094 T E A + S + T + V TE P + S + + G S Sbjct: 3023 DSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIG--INEESV 3080 Query: 2095 LGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEW 2154 G I P+ + + L G T TS +P Sbjct: 3081 EGTAIYLPGPD---------------RCKMNPCLNGGT---CYPTETSYVCTCVPGY--- 3119 Query: 2155 KRESESTAAAPARSCAEEPCGAG-TCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKY 2213 S C PC G TC + CLC P Y G C D E C+ GW+K+ Sbjct: 3120 ---SGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKF 3176 Query: 2214 QGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGD 2273 QG CY++F R TW AER CR Q +HL+SI++ EEQ FVN DYQWIGLND+ E D Sbjct: 3177 QGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHD 3236 Query: 2274 FRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVAC 2333 FRW+DG +Q+ENWRPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYHL +TCKKGTVAC Sbjct: 3237 FRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVAC 3296 Query: 2334 GEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPT 2393 G+PPVVE+A+TFG+ K RYEINSL+RY C +GF+QRH+PTIRC +G W P+ITC +P+ Sbjct: 3297 GQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPS 3356 Query: 2394 TYKR 2397 Y+R Sbjct: 3357 AYQR 3360 Score = 40.8 bits (94), Expect = 0.016 Identities = 179/769 (23%), Positives = 269/769 (34%), Gaps = 105/769 (13%) Query: 713 PVEEETTAVPSGETTAILEFTT--------EPENQTEWEPAYTPVGTSPLPGI------- 757 P EET V + EF EN+ E E + P + Sbjct: 1356 PCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKH 1415 Query: 758 LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFP----SEEPSPSEEPFPSVRPFP 813 L T P E+ G + PS + S P E S + +P S Sbjct: 1416 LVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTE 1475 Query: 814 SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873 S+E+ E +P SE S E P+ VP E S + GA V+ T Sbjct: 1476 SLEVTWKPETYPET----SEHFSGGEPDVFPT--VPFHEEFESGTAKKGAESVTERDTEV 1529 Query: 874 GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933 G + L + +SG + D +S + E E+ TPT Sbjct: 1530 GHQAHEHTEPVSLFPEESSGEIAIDQESQ----KIAFARATEVTFGEEVEKSTSVTYTPT 1585 Query: 934 VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993 + +PS A V + ++L T S V E T V ++S Sbjct: 1586 I--VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV------------EATPRQVVELS 1631 Query: 994 GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053 G S + E + ED +T V D+S + + L T D S + Sbjct: 1632 GSSSIPITEGSGEAEEDE---------DTMFTMVTDLSQRNTTDTLITL-----DTSRII 1677 Query: 1054 SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG-LPSGEVLETAAPGVEDISGLPSG 1112 + E A + +S PS +V+ T D S + S V E E +G S Sbjct: 1678 TESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAST 1737 Query: 1113 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1172 + ++ + + LP E +P V S + + + + + + Sbjct: 1738 FEVYSSTQRSDQLI-LP----FELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPV 1792 Query: 1173 ETAAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231 T +E++ G + E PGV++ ++ LP G + + P + + Sbjct: 1793 FTETNTLENL-GAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS 1851 Query: 1232 AAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGV--EDISGLPSGEVLET 1288 + VE + EV T +P VE S P+G VL T V E+I+ S E++ + Sbjct: 1852 FSLNVE-YAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQT-SREIVIS 1909 Query: 1289 TAPGVE----EISGLPSGEVLETTAPG-VDEISGLPSGEVLETTAPGVEEISGLPSGEVL 1343 G EI G +G LE G E S + E T + E SG + Sbjct: 1910 ERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETV--MMEGSGDAAFRDT 1967 Query: 1344 ETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGL 1401 +TS S V + +S + D G PS +V TSA E+ S SGE L Sbjct: 1968 QTSPSTVPT-----------SVHISHISDSEG-PSSTMVSTSAFPWEEFTSSAEGSGEQL 2015 Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGT 1450 T +S V + LPS + +AS D EGL EVGT Sbjct: 2016 VTVSSSVVPV--LPSAVQKFSGTASSIID--------EGL----GEVGT 2050 Score = 38.1 bits (87), Expect = 0.11 Identities = 121/549 (22%), Positives = 188/549 (34%), Gaps = 117/549 (21%) Query: 1614 EIPG--LFGVSGQPSGF---------PDTSGETSGVTELSGLSSGQPGISGEASGVLYGT 1662 E+P ++ VS QPS DTS S T + G +G AS T Sbjct: 1683 EVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAS-----T 1737 Query: 1663 SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGI-TFVDTS 1721 + + T S + +L SG L + T S + F +T+ Sbjct: 1738 FEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETN 1797 Query: 1722 LVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFS 1781 +E E S+ G+ G L V + Q SG + T+ FS Sbjct: 1798 TLENLGAQTTEHS---SIHQPGVQEGLTTLPRSPASVFME-QGSGEAAADPETTTVSSFS 1853 Query: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841 E + ++ + G+ P S P+ +++DR + E++TQ T++E Sbjct: 1854 LN----VEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQ--TSREIV 1907 Query: 1842 EGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS 1901 I E G + ++ G +GF P FSGDF + VS Sbjct: 1908 -----ISERLGEPNYGAEIRGFSTGF-----------------PLEEDFSGDFREYSTVS 1945 Query: 1902 G----ESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSG 1957 E +V M SG+A+ F + T P+ P H + +S G Sbjct: 1946 HPIAKEETVMMEGSGDAA-----------FRDTQTSPSTV------PTSVHISHISDSEG 1988 Query: 1958 KVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSE 2017 ST TSA+P F +SA E SG ++ Sbjct: 1989 PSSTM------------------------VSTSAFPWEEFTSSA------EGSGEQLVTV 2018 Query: 2018 TTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTT--TSDV-GTEAPGLPSAT 2074 ++S G + S + GE E+ ST T++V GT+AP Sbjct: 2019 SSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAP------ 2072 Query: 2075 PTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEET 2134 + ++SG +S + Q T P W++Q P +E E++S EE Sbjct: 2073 --VEKEEVKVSGTVSTNFPQ------TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEK 2124 Query: 2135 HTVETATSP 2143 SP Sbjct: 2125 SFESPQNSP 2133 >gi|187607300 versican isoform 2 [Homo sapiens] Length = 655 Score = 361 bits (926), Expect = 5e-99 Identities = 177/357 (49%), Positives = 240/357 (67%), Gaps = 19/357 (5%) Query: 3 TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62 ++LW+ TL ++T A+ V + + P+R L +++PC+F M + Sbjct: 7 SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54 Query: 63 APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116 + +T+ RIKWS++ +K E +LVA G +++ Y+ +VS+P +P DA Sbjct: 55 SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113 Query: 117 TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176 +L V L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL Sbjct: 114 SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173 Query: 177 QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236 A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI PR GCYGDK GVRTYG R Sbjct: 174 DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233 Query: 237 DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296 ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC ARLAT G+L AW+ G D Sbjct: 234 SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293 Query: 297 CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGED 353 C GWL+D SVR+P++ AR CGG LLGVRT+Y NQTG+P P SR+DA C+ D Sbjct: 294 CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPD 350 Score = 332 bits (851), Expect = 3e-90 Identities = 142/230 (61%), Positives = 174/230 (75%), Gaps = 1/230 (0%) Query: 2169 CAEEPCGAG-TCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETW 2227 C PC G TC + CLC P Y G C D E C+ GW+K+QG CY++F R TW Sbjct: 390 CHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTW 449 Query: 2228 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENW 2287 AER CR Q +HL+SI++ EEQ FVN DYQWIGLND+ E DFRW+DG +Q+ENW Sbjct: 450 DAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENW 509 Query: 2288 RPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQ 2347 RPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYHL +TCKKGTVACG+PPVVE+A+TFG+ Sbjct: 510 RPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGK 569 Query: 2348 KKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKR 2397 K RYEINSL+RY C +GF+QRH+PTIRC +G W P+ITC +P+ Y+R Sbjct: 570 MKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR 619 Score = 255 bits (652), Expect = 3e-67 Identities = 120/199 (60%), Positives = 144/199 (72%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVFHYR +RY+L FE AQ+ACL GAVIA+PEQL AAYE G+EQCDAGWL DQTVRY Sbjct: 149 GVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRY 208 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596 PI +PR C GDK GVRTYG R ETYDVYC+VD L+G+VF T +FTF+EA + Sbjct: 209 PIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAK 268 Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656 CE+ +A LAT G+L AAW G D+C GWL+D S+R+P+ R CGG GVRT+Y + Sbjct: 269 ECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRF 328 Query: 657 PNQTGLPDPLSRHHAFCFR 675 NQTG P P SR A+CF+ Sbjct: 329 ENQTGFPPPDSRFDAYCFK 347 >gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] Length = 1321 Score = 328 bits (840), Expect = 5e-89 Identities = 161/315 (51%), Positives = 209/315 (66%), Gaps = 9/315 (2%) Query: 39 LRVLLGTSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRV----SKEKEVVLLVATEGRV 94 ++ L + +PC F + PS A APRIKW++V + +++ +LVA + V Sbjct: 47 VQAALAELVALPCLFT-----LQPRPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVV 101 Query: 95 RVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIV 154 RV ++Q +VSLP+YP ++ATL + LR++DSG+YRC+V+ GIED + + + V G+V Sbjct: 102 RVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVV 161 Query: 155 FHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIH 214 FHYR+ RY L F AQ AC +SAIIA P LQAA+EDGF CDAGWL+D+TVRYPI Sbjct: 162 FHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPIT 221 Query: 215 TPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECR 274 R GCYGD+ PGVR+YG R+ E YDVYCFA E+ GEVFY + T A +CR Sbjct: 222 QSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCR 281 Query: 275 RLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQ 334 R GA LA+ GQL+LAW G+D C GWLAD SVRYPI R CGG GVRTVY AN+ Sbjct: 282 RQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANR 341 Query: 335 TGYPDPSSRYDAICY 349 TG+P P+ R+DA C+ Sbjct: 342 TGFPSPAERFDAYCF 356 Score = 313 bits (802), Expect = 1e-84 Identities = 210/636 (33%), Positives = 304/636 (47%), Gaps = 80/636 (12%) Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850 +GE+S A++ A + S +P +P+V+ R + TA E P+G+ + Sbjct: 708 TGETSPAQVNK-----AEHSSSSP--WPSVN---RNVAVGFVPTETATE----PTGLRGI 753 Query: 1851 SGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGT 1910 G+ SG D + + SGLQ+ + E +P + Y G AS+ S +G+ Sbjct: 754 PGSESGVFDTAESPT-----SGLQATVDEVQ-DPWPSVYSKGLDASSP------SAPLGS 801 Query: 1911 SGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATP 1970 G +P+VT +V PT++ T TP ++SG Sbjct: 802 PGVFL-VPKVTPNLEPWVATDEGPTVNPM-----DSTVTPAPSDASGIWE---------- 845 Query: 1971 VLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSP-------DLSETTSAFH 2023 PGS V E + T+ P+ S + + G L ++S H Sbjct: 846 --PGS-----QVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPH 898 Query: 2024 EANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGD--R 2081 ++ G SG+++ + P V + T + VG E+ + S PT D Sbjct: 899 PEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVG-ESASVSSGEPTVPWDPSS 957 Query: 2082 TEISGDLSGHTSQLGVVISTSIPESEWTQQT--QRPAETHLEIESSSLLYSGEETHTVET 2139 T + L +L V+ + ES W + + PA + + + EE H+ Sbjct: 958 TLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPA-----LPGTPMNAGAEEVHSDPC 1012 Query: 2140 ATSP--------TDASIPASPEWKRESESTAAAPARSCAEEPC-GAGTCKETEGHVICLC 2190 +P + ++ + + C PC GTC + +CLC Sbjct: 1013 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLC 1072 Query: 2191 PPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQ 2250 P Y G C D E C+ GW+K+QGHCYR+F R W DAE+ CR + HL+S+ +PEE Sbjct: 1073 LPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEH 1132 Query: 2251 EFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEK 2310 F+N+ + WIGLNDR +E DF+W+D +QFENWR NQPDNFFA GEDCVVM+ HE Sbjct: 1133 SFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHES 1192 Query: 2311 GEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRH 2370 G WNDVPCNY+LP+ CKKGTV CG PP VE+A G +K +Y +++ VRYQC EGF Q H Sbjct: 1193 GRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHH 1252 Query: 2371 MPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRH 2406 + TIRC+ +G W+ PQI CT P R R RH Sbjct: 1253 VATIRCRSNGKWDRPQIVCTKP-----RRSHRMRRH 1283 Score = 262 bits (669), Expect = 3e-69 Identities = 238/754 (31%), Positives = 321/754 (42%), Gaps = 94/754 (12%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVFHYR RY+LTF EAQ+AC + A+IA+P LQAA+E G++ CDAGWL D+TVRY Sbjct: 159 GVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRY 218 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596 PI R C GD+ S PGVR+YG R E YDVYCF L GEVF+ + T A Sbjct: 219 PITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARA 278 Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656 C A LA+ GQL+ AW GLD+C GWLADGS+RYPI TPR CGG PGVRTVY + Sbjct: 279 QCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRF 338 Query: 657 PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAV--PV 714 N+TG P P R A+CFR P + G T SG E I++ P V + + Sbjct: 339 ANRTGFPSPAERFDAYCFR----AHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTL 394 Query: 715 EEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEG 774 EEE P + + E E + + + +P +L +W PTG ST Sbjct: 395 EEEEVVTPDFQEPLVSSGEEETLILEEKQESQQTLSPTPGDPMLASW-PTGEVW-LSTVA 452 Query: 775 PSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFP--------S 826 PS +++ + + S +EV P++ F + + F +EP P S Sbjct: 453 PSPSDMGAGTAASSHTEVA-PTDPMPRRRGRFKGL----NGRYFQQQEPEPGLQGGMEAS 507 Query: 827 KEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQL 886 +P SE EP P + TE+ SG +S +P D T D+ G G+ Sbjct: 508 AQPPTSEAAVNQMEP----PLAMAVTEMLGSG-QSRSP--WADLTNEVDMPGAGSAGGKS 560 Query: 887 SGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPS----TPTVGELPSGAE 942 S + P + V + S P + E+ E PS TP + P A Sbjct: 561 SPEPWLWPP----------TMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEAT 610 Query: 943 ILEGS-----ASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPS 997 + S A V LP +L + LP + T A VE Sbjct: 611 VSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWM-----LPHPTPISTEANRVE-----AH 660 Query: 998 GEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLET--TAPGVEDISGLPSG 1055 GE T P P+ E + P +S P+G+ E T P +G Sbjct: 661 GEATATAPPS-------PAAETKVYSLP----LSLTPTGQGGEAMPTTPESPRADFRETG 709 Query: 1056 EVLETTAPGVEDISGLP---------SGEVLETTAPGVEDISGLPSGEVLETAAPGVEDI 1106 E E S P G V TA + G+P E GV D Sbjct: 710 ETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGIPGSE------SGVFDT 763 Query: 1107 SGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1166 + P+ L+ V+D + L+ ++P G P ++ P +E Sbjct: 764 AESPTSG-LQATVDEVQDPWPSVYSKGLDASSPSAP--LGSPGVFLVPKVTPNLEPWVAT 820 Query: 1167 PSGEVL----ETAAPGVEDISGL--PSGEVLETA 1194 G + T P D SG+ P +V E A Sbjct: 821 DEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEA 854 Score = 39.7 bits (91), Expect = 0.036 Identities = 99/407 (24%), Positives = 154/407 (37%), Gaps = 66/407 (16%) Query: 654 YLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEG--GTPTSPSGVEEWIVTQVVPGVAA 711 ++ P+ T + +R A +A PSP E P S +T G A Sbjct: 642 WMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSLPLS--------LTPTGQGGEA 693 Query: 712 VPVEEETTAVP---SGETTAILEFTTEPENQTEWEPA-------YTPVGTSPLPGILPTW 761 +P E+ +GET+ E + + W + P T+ P L Sbjct: 694 MPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGI 753 Query: 762 PPTGAATEESTEGPSATEVPSASE--EPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFP 819 P + + ++ E P++ + E +P PS + SPS P S F ++ P Sbjct: 754 PGSESGVFDTAESPTSGLQATVDEVQDPWPSVYSKGLDASSPSA-PLGSPGVFLVPKVTP 812 Query: 820 SEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGH 879 + EP+ + + P+ P S PS W EE+ + +S + Sbjct: 813 NLEPWVATDEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTP 872 Query: 880 LDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPS 939 L Q GD+ G+P+ ST+GS P E+++E T S Sbjct: 873 LTTLEQ--GDKV-GVPA--------MSTLGSSSSQPHPEP---EDQVETQGT-------S 911 Query: 940 GAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGE 999 GA + +S +G +P G +A+ VG+ + + SG E T P PS Sbjct: 912 GASVPPHQSSPLGK-PAVPPG---TPTAASVGESASVSSG---EPTVPWD------PSST 958 Query: 1000 VLETTAPGVEDISGLPSGEVLETTAPGVEDI-SGLPSGEVLETTAPG 1045 +L T G+ED EVL +PGVE + SGE E PG Sbjct: 959 LLPVTL-GIEDF----ELEVL-AGSPGVESFWEEVASGE--EPALPG 997 Score = 35.4 bits (80), Expect = 0.68 Identities = 154/730 (21%), Positives = 250/730 (34%), Gaps = 118/730 (16%) Query: 1286 LETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEE---ISGLPSGEV 1342 LET + G E GE+L P V E+ P+ E E P +E SG + Sbjct: 368 LETPSSGDE-------GEILSAEGPPVRELE--PTLEEEEVVTPDFQEPLVSSGEEETLI 418 Query: 1343 LETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLE 1402 LE + LS P G ++ P+GEV + V+ PS G Sbjct: 419 LEEKQESQQTLSPTP-----------GDPMLASWPTGEV------WLSTVAPSPSDMGAG 461 Query: 1403 TSASG---VEDLSRLPSGEEVLE-ISASGFGDLSGLPSGGEGLETSA----SEVGTDLSG 1454 T+AS V +P + ++ F P G+E SA SE + Sbjct: 462 TAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAVNQME 521 Query: 1455 LPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPET-----S 1509 P E SG S DL + ++D+ +G+ G +PE + Sbjct: 522 PPLAMAVTEMLGSGQSR-----SPWADL----TNEVDMPG--AGSAGGKSSPEPWLWPPT 570 Query: 1510 GLPSGFSGEYSG----VDLGSGPPS--GLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563 +P SG ++ GP + PD P TVS E +T+ + Sbjct: 571 MVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLE-ATVSAPSPAPWEAFPVATSPD 629 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSG 1623 L + G + IS A+ + + E + A SP ++ L +S Sbjct: 630 LPMMAML----RGPKEWMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSL-PLSL 684 Query: 1624 QPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVP-DLS 1682 P+G + T+ + + + + + +S P+ + + VP + + Sbjct: 685 TPTGQGGEAMPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETA 744 Query: 1683 GQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELS 1742 +P+GL G G+ SGV D TSG + T + ++ SV Sbjct: 745 TEPTGLRGIPGSESGVFDTAESPTSG----------------LQATVDEVQDPWPSVYSK 788 Query: 1743 GLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSS 1802 GL + S V + + + ++ T + P + + S + ++S G Sbjct: 789 GLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPAPSDAS----GIW 844 Query: 1803 LPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSG 1862 P + ++ +D ++V +T + G L G+ S P Sbjct: 845 EPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTL---GSSSSQPHPEP 901 Query: 1863 EHSGFLDLSGLQSGLIEP--------SGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEA 1914 E ++ G + P PPGTP + S + SGE +V S Sbjct: 902 EDQ--VETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPS--- 956 Query: 1915 SGLPEVTLITSEF----------VEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGD 1964 S L VTL +F VE E S G+ P + TP ++G D Sbjct: 957 STLLPVTLGIEDFELEVLAGSPGVESFWEEVAS---GEEPALPGTPM---NAGAEEVHSD 1010 Query: 1965 ISGATPVLPG 1974 P L G Sbjct: 1011 PCENNPCLHG 1020 >gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sapiens] Length = 360 Score = 224 bits (572), Expect = 6e-58 Identities = 131/313 (41%), Positives = 178/313 (56%), Gaps = 25/313 (7%) Query: 44 GTSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRVSK----EKEVVLLVATEGRVRVNSA 99 G S+ +PC + P +P R+KW ++S+ EK+V LVA R R Sbjct: 63 GASVILPCRY--RYEPALVSPRRV----RVKWWKLSENGAPEKDV--LVAIGLRHRSFGD 114 Query: 100 YQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRA 159 YQ +V L D +LE+Q LR D G YRCEV+ G+ED +E+ ++G+VF Y++ Sbjct: 115 YQGRVHLRQDKE--HDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQS 172 Query: 160 ISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREG 219 + RY +F Q+ C + +A++A+ EQL A+E+G C+AGWL D TV+YPI PR+ Sbjct: 173 PNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQP 232 Query: 220 CYGDKDEFPGVRTYGIRDTN-ETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGA 278 C G PGVR+YG R YDV+CFA ++G V+Y PEK T EA C+ A Sbjct: 233 C-GGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDA 291 Query: 279 RLATTGQLYLAWQ-AGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGY 337 +A GQL+ AW+ G+D C AGWLAD SVRYP+ PNCG GVR+ G+ Sbjct: 292 TIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF-------GF 344 Query: 338 PDPSSR-YDAICY 349 PDP SR Y CY Sbjct: 345 PDPQSRLYGVYCY 357 Score = 192 bits (489), Expect = 3e-48 Identities = 100/202 (49%), Positives = 127/202 (62%), Gaps = 11/202 (5%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF Y+ RY F E QQ C AV+AS EQL A+E G + C+AGWL+D TV+Y Sbjct: 165 GVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQY 224 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVR-PSTETYDVYCFVDRLEGEVFFATRLEQFTFQEAL 595 PI+ PR PC G +PGVR+YG R YDV+CF L+G V++ E+ T EA Sbjct: 225 PIMLPRQPC-GGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAR 283 Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654 E C+ +AT+A GQL+AAW GLD+C AGWLADGS+RYP+V P P CG +PGVR+ Sbjct: 284 EACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF- 342 Query: 655 LYPNQTGLPDPLSR-HHAFCFR 675 G PDP SR + +C+R Sbjct: 343 ------GFPDPQSRLYGVYCYR 358 >gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo sapiens] Length = 354 Score = 212 bits (540), Expect = 3e-54 Identities = 129/343 (37%), Positives = 182/343 (53%), Gaps = 30/343 (8%) Query: 22 TSDHDNSLSVSIPQPSPLRVLL---------GTSLTIPCYFI-DPMHPVTTAPSTAPLAP 71 T DHD ++ + L V G ++T+PC F DP TA + Sbjct: 23 TLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDP-----TAFGSGIHKI 77 Query: 72 RIKWSRVSKE--KEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSG 129 RIKW++++ + KEV + V+ + YQ +V L SDA+L + L D G Sbjct: 78 RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKG--GSDSDASLVITDLTLEDYG 135 Query: 130 VYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQ 189 Y+CEV+ G+ED + + ++G+VF Y RY L+F AQ+ACL A+IA+ +QL Sbjct: 136 RYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLY 195 Query: 190 AAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNET-YDVYCFA 248 A+ G C+AGWL+D +V+YPI PRE C G ++ PGVR YG D +++ YDV+CF Sbjct: 196 DAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFT 254 Query: 249 EEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQ-AGMDMCSAGWLADRSV 307 G +Y P K T+ EA C GA++A GQ++ AW+ G D C AGWLAD SV Sbjct: 255 SNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSV 314 Query: 308 RYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICY 349 RYPIS+ R C VR V G+PD + Y C+ Sbjct: 315 RYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYCF 350 Score = 169 bits (429), Expect = 2e-41 Identities = 91/202 (45%), Positives = 120/202 (59%), Gaps = 11/202 (5%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF Y P RY+L F EAQQACL AVIAS +QL A+ G + C+AGWL D +V+Y Sbjct: 158 GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQY 217 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTET-YDVYCFVDRLEGEVFFATRLEQFTFQEAL 595 PI PR PC G +++ PGVR YG ++ YDV+CF G ++ + T+ EA+ Sbjct: 218 PITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAV 276 Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654 + C + A +A GQ++AAW G D+C AGWLADGS+RYPI PR C + VR V Sbjct: 277 QACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV- 335 Query: 655 LYPNQTGLPDPLSR-HHAFCFR 675 G PD + + +CFR Sbjct: 336 ------GFPDKKHKLYGVYCFR 351 >gi|11141887 brain link protein-1 [Homo sapiens] Length = 340 Score = 189 bits (481), Expect = 2e-47 Identities = 114/317 (35%), Positives = 169/317 (53%), Gaps = 30/317 (9%) Query: 50 PCYFIDPMHPV--------TTAP---STAPLAPRIKWSRVS--KEKEVVLLVATEGRVRV 96 P Y + P+H V T P T P + +++WS+V + +E ++L+ R Sbjct: 34 PHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLHARG 93 Query: 97 NSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFH 156 + + + DA+L + +R D G YRCE+++GIED L + ++G+VF Sbjct: 94 YGPLGGRARMRRGHRL--DASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFP 151 Query: 157 YRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTP 216 Y+ RY ++ A++AC + +AT QL A+ +G C+AGWL + +VRYP+ T Sbjct: 152 YQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTA 211 Query: 217 REGCYGDKDEFPGVRTYGIRD-TNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRR 275 R C G PG+R+YG RD + YD +CF + G+VF+ P + T EA CRR Sbjct: 212 RAPCGGRGR--PGIRSYGPRDRMRDRYDAFCFTSALAGQVFFV--PGRLTLSEAHAACRR 267 Query: 276 LGARLATTGQLYLAWQ-AGMDMCSAGWLADRSVRYPISKARPNCGG-NLLGVRTVYVHAN 333 GA +A G LY AW+ +G+D C GWLAD SVR+PI+ RP CGG GVR+ Sbjct: 268 RGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSF----- 322 Query: 334 QTGYPDP-SSRYDAICY 349 G+P P + Y CY Sbjct: 323 --GFPRPQQAAYGTYCY 337 Score = 159 bits (401), Expect = 4e-38 Identities = 83/179 (46%), Positives = 107/179 (59%), Gaps = 7/179 (3%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF Y+P RY + EA+QAC +A+ QL A+ G + C+AGWL + +VRY Sbjct: 147 GVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRY 206 Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRP-STETYDVYCFVDRLEGEVFFATRLEQFTFQEAL 595 P+++ R PC G PG+R+YG R + YD +CF L G+VFF + T EA Sbjct: 207 PVLTARAPCGG--RGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVP--GRLTLSEAH 262 Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGG-DKPGVRT 652 C A +A G LYAAW GLD+C GWLADGS+R+PI TPRP CGG PGVR+ Sbjct: 263 AACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRS 321 Score = 83.6 bits (205), Expect = 2e-15 Identities = 42/88 (47%), Positives = 56/88 (63%), Gaps = 7/88 (7%) Query: 588 QFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGG-D 646 QF + EA + CE + LAT QLY AW+ GLD C AGWL +GS+RYP++T R CGG Sbjct: 160 QFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRG 219 Query: 647 KPGVRTVYLYPNQTGLPDPLSRHHAFCF 674 +PG+R+ Y + + D R+ AFCF Sbjct: 220 RPGIRS---YGPRDRMRD---RYDAFCF 241 >gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sapiens] Length = 402 Score = 189 bits (481), Expect = 2e-47 Identities = 112/307 (36%), Positives = 158/307 (51%), Gaps = 22/307 (7%) Query: 72 RIKWSRVSKEKEVV-LLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGV 130 R+KW++V + VA + R +Y+ + L P DA+L ++++ D G Sbjct: 83 RLKWTKVVDPLAFTDVFVALGPQHRAFGSYRGRAELQGDG--PGDASLVLRNVTLQDYGR 140 Query: 131 YRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQA 190 Y CEV + +ED +++ ++G+VF Y RY L F AQRAC + I+A+ EQL A Sbjct: 141 YECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHA 200 Query: 191 AYEDGFHQCDAGWLADQTVRYPIHTPREGC---------YGDKDEFPGVRTYGIR-DTNE 240 A+ DG C+AGWL D +V+YP++ PRE C G D G+R YG R + E Sbjct: 201 AWRDGLDWCNAGWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEE 260 Query: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAG-MDMCSA 299 YD +CF + G VF+ F AA C GA +A GQL+ AW+ +D C+A Sbjct: 261 RYDAFCFTSNLPGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTA 320 Query: 300 GWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICYTGEDFVDIP 358 GWLAD S RYPI R CGG GVR++ G+PD + R + CY D Sbjct: 321 GWLADGSARYPIVNPRARCGGRRPGVRSL-------GFPDATRRLFGVYCYRAPGAPDPA 373 Query: 359 ENFFGVG 365 +G G Sbjct: 374 PGGWGWG 380 Score = 185 bits (470), Expect = 4e-46 Identities = 102/221 (46%), Positives = 127/221 (57%), Gaps = 20/221 (9%) Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536 GVVF Y P RY LTF EAQ+AC ++AS EQL AA+ G + C+AGWLRD +V+Y Sbjct: 162 GVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQY 221 Query: 537 PIVSPRTPC---------VGDKDSSPGVRTYGVRPST-ETYDVYCFVDRLEGEVFFATRL 586 P+ PR PC G D++ G+R YG R + E YD +CF L G VFF L Sbjct: 222 PVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPL 281 Query: 587 EQFTFQEALEFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGG 645 F A C + A +A GQL+AAW + LD+C AGWLADGS RYPIV PR CGG Sbjct: 282 RPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGG 341 Query: 646 DKPGVRTVYLYPNQTGLPDPLSR-HHAFCFRGISAV-PSPG 684 +PGVR++ G PD R +C+R A P+PG Sbjct: 342 RRPGVRSL-------GFPDATRRLFGVYCYRAPGAPDPAPG 375 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 149 bits (375), Expect = 4e-35 Identities = 302/1164 (25%), Positives = 396/1164 (34%), Gaps = 197/1164 (16%) Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSP----SEEPFPS 808 P P PT PP G + P +P + +P P P P P Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148 Query: 809 VRPFPSVELFPSEE----------PFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSG 858 P + + + P P+ P P P S P SP P + P Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHP--GSPGSPGYQGPPGEP 206 Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918 ++G +G G + SG D SG P G P E GL Sbjct: 207 GQAGP-------SGPPGPPGAIGPSGPAGKDGESGRP---------------GRPGERGL 244 Query: 919 PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPS 978 P P + P+G G G G +GE ET A G+ +GLP Sbjct: 245 PG-----------PPGIKGPAGIPGFPG-MKGHRGFDG-RNGEKGETGAPGLKGENGLPG 291 Query: 979 -----GEVLETTAPGVEDISGLPS-----------GEVLETTAPGVEDISGLP-----SG 1017 G + APG GLP G + PG +G P G Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351 Query: 1018 EVLETTAPGVEDISGL-----PSGEVLETTAPGVEDISGLP--SGEVLETTAPGVEDISG 1070 EV +PG G P G PG I+G P GE+ PG + G Sbjct: 352 EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMG 411 Query: 1071 L--PSGEVLETTAPGVEDISGLP-----SGEVLETAAPGVEDISGLP--SGEVLETAAPG 1121 P G APG+ +G P GE G I G+P GE + +PG Sbjct: 412 ARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG 471 Query: 1122 VEDISGLPSGEVLETAAPGVE---DISGLP--SGEVLETAAPGVEDISGLPSGEVLETAA 1176 +GLP G E APG +G+P G E APG G +GE Sbjct: 472 EPGANGLP-GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG-AAGEPGRDGV 529 Query: 1177 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1236 PG + G+P PG + G P G E+ PG SG P G+ PG Sbjct: 530 PGGPGMRGMPG----SPGGPGSDGKPG-PPGSQGESGRPGPPGPSG-PRGQPGVMGFPGP 583 Query: 1237 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEI 1296 + G P G+ E PG G P G+ ET G +G P G+ +T PG + + Sbjct: 584 KGNDGAP-GKNGERGGPGGPGPQG-PPGKNGETGPQGPPGPTG-PGGDKGDTGPPGPQGL 640 Query: 1297 SGLPS-----GEVLETTAPGVDEISGLPS--GEVLETTAPGVEEISGLPSGEVLETSTSA 1349 GLP GE + PG +G P G + APG GL L Sbjct: 641 QGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700 Query: 1350 VGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGV- 1408 G G + G +G + G+P GE + G + P G G A GV Sbjct: 701 PGPEGGKGAAGPPGPPGAAGTPGLQGMP-GERGGLGSPGPKGDKGEPGGPG----ADGVP 755 Query: 1409 -EDLSRLPSGE-----EVLEISASGFGDLSGLP--SGGEGLETSASEVGTDLSGLPSGRE 1460 +D R P+G + G G GLP +G G E G P G Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG------PPGPA 809 Query: 1461 GLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLG--SGQAPETSGLPSGFSGE 1518 G GA +G P GK + A G+ G P G G G P P G GE Sbjct: 810 GF----PGAPGQNGEPGGKGE--RGAPGEKGEGG-PPGVAGPPGGSGPAGPPGPQGVKGE 862 Query: 1519 YSGVDLGSGPPSGLPDFSGLP-----SGFPTVSLVDSTLVEVVTASTASELEGRGTIGIS 1573 G +G P GLP +G P + + A G+ G+S Sbjct: 863 RGSP--GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920 Query: 1574 GAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ-----PSGF 1628 G +G P G + S A G P G + G+ G++G P G Sbjct: 921 GPKGDAGQP---------------GEKGSPGAQGPPGAPGPL-GIAGITGARGLAGPPGM 964 Query: 1629 PDTSGE--TSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP- 1685 P G GV SG G G+SGE G P G+ L+G T+G P G P Sbjct: 965 PGPRGSPGPQGVKGESG-KPGANGLSGER-----GPPGPQGLPGLAG-TAGEPGRDGNPG 1017 Query: 1686 -SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEG--------- 1735 GLPG G+ G D + G+ + G + + + E G Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077 Query: 1736 -LGSVELSGL--PSGEADLSGKSGMVDVSGQ--FSGTVDSSGFTSQTPEFSGLPSGIAEV 1790 GS G P G+ +G+ G + G F G + G +P +G I Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG----SPGPAGQQGAIGSP 1133 Query: 1791 SGESSRAEIGSSLPSGAYYGSGTP 1814 R +G S P G SG P Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHP 1157 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 142 bits (357), Expect = 5e-33 Identities = 335/1330 (25%), Positives = 444/1330 (33%), Gaps = 242/1330 (18%) Query: 625 GWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPG 684 G L G +P + P G PG++ P TG P P P P Sbjct: 168 GMLLKGERGFPGIPGTPGPPG-LPGLQGPVGPPGFTGPPGP------------PGPPGPP 214 Query: 685 EEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEP 744 E+G S G + Q V G VP + + +F T+ E + EP Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKG--------DFATKGEKGQKGEP 266 Query: 745 AYTPVGTSPLPGI----LPTWP-PTGAATEESTEGPSATE-VPSASEEPSPSEVPFPSEE 798 G +PG+ P P P G ++ +G + P P P E Sbjct: 267 -----GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGE 321 Query: 799 PSPSEEPFPSVRPFPSVELFPSEE------PFPSKEPSPSEEPSASEEPYTPSPPVPSWT 852 + P P + L E P P EP P P +P P PVP Sbjct: 322 KGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPG-- 379 Query: 853 ELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGL 912 ++GAP G+ GD G + LP G GL GS Sbjct: 380 -------QAGAPGFPGERGEKGD-----------RGFPGTSLP-GPSGRDGLPGPPGS-- 418 Query: 913 PVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGD 972 P G P +E P + P G G +G+ G L G Sbjct: 419 PGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE-KGQKGESCLICDIDGYRG 477 Query: 973 LSGL--PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDI 1030 G P GE+ PG + GLP + GV + G P G PG + Sbjct: 478 PPGPQGPPGEIGFPGQPGAKGDRGLPGRD-------GVAGVPG-PQGTPGLIGQPGAK-- 527 Query: 1031 SGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS 1088 G P + G + G P G +PG + GLP G + G++ Sbjct: 528 -GEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP-GPKGSPGSVGLKGER 585 Query: 1089 GLPSGEVLETAAPGVEDISGLPSGEVLETAAP-GVEDISGLPSGEVLETAAPGVEDISGL 1147 G P G PG +G P A P G + +G P G +PG+ G Sbjct: 586 GPPGG----VGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGG----PGSPGLPGPKGE 637 Query: 1148 PSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1205 P V PG E + G P G + PG GLP GE PG+ G P Sbjct: 638 PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLP-GEKGAVGQPGI----GFP 692 Query: 1206 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE 1265 PG + + GLP G++ PG +GLP PGV+ G P Sbjct: 693 -------GPPGPKGVDGLP-GDMGPPGTPGRPGFNGLPGN-------PGVQGQKGEPG-- 735 Query: 1266 VLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS--GEVLETTAPGVDEISGLPSGEV 1323 PG++ + GLP PG + G+P GE PG+ I G P Sbjct: 736 ---VGLPGLKGLPGLPG----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788 Query: 1324 L--ETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPS-GGEVLEISVSGVEDISGLPSGE 1380 L +PGV I P G LSG P GE G+ D+ G P G+ Sbjct: 789 LPGSVGSPGVPGIG--PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGL-DMPG-PKGD 844 Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 GI S LP G + G + P + + + + S P G G Sbjct: 845 KGAQGLPGITGQSGLPGLPGQQ----GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPG 900 Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDL-VGSASGDL-DLGKL--- 1495 L + G S P G GL+ G L G P + + +GS G D G+ Sbjct: 901 LPGEKGDHGFPGSSGPRGDPGLK-GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQI 959 Query: 1496 -PSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVE 1554 P G GS P T G+P G G+ G P G P SG P G P + Sbjct: 960 GPIGEKGSRGDPGTPGVP-GKDGQAG--QPGQPGPKGDPGISGTP-GAPGL--------- 1006 Query: 1555 VVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVS 1612 + G G G G + G+P + + GLP G+ +G P + Sbjct: 1007 ---PGPKGSVGGMGLPGTPGEKGVPGIPGPQ-----GSPGLPGDKGAKGEKGQAGPPGIG 1058 Query: 1613 GEIPGLFGVSGQP--SGFPDTSGE--TSGVTELSGLSSGQPGISGEASGVLYGTSQPFGI 1668 IPGL G G +GFP + GE G + G+ G PG+ G V Y S G+ Sbjct: 1059 --IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM-PGSPGLKGSPGSVGYPGSP--GL 1113 Query: 1669 TDLSGETSGVPDLSGQP-----SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLV 1723 G+ G+P L G P +GLPG G T + G S+G Sbjct: 1114 PGEKGD-KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG--------- 1163 Query: 1724 EVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPE--FS 1781 K E GL G P + D G G V F G S G E F Sbjct: 1164 ------EKGEPGLPGRGFPGFPGAKGD-KGSKGEVG----FPGLAGSPGIPGSKGEQGFM 1212 Query: 1782 GLPS-----GIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPT 1836 G P G+ G ++ G P G G P Sbjct: 1213 GPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM------------------- 1253 Query: 1837 AQEAGEGPSGILELSGAHS--------GAPDMSGEHS--GFLDLSGL--QSGLIEPSGE- 1883 GP G+ + G GAP + G GF + G+ G+ G+ Sbjct: 1254 ------GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDM 1307 Query: 1884 -PPGTPYFSG 1892 PPG P F G Sbjct: 1308 GPPGVPGFQG 1317 Score = 115 bits (289), Expect = 4e-25 Identities = 266/1067 (24%), Positives = 351/1067 (32%), Gaps = 202/1067 (18%) Query: 743 EPAYT---------PVGTSPLPGILPTWPPTGAATEESTEGPSAT-------EVPSASEE 786 +P YT P G PGI G E+ +G S P + Sbjct: 424 QPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQG 483 Query: 787 PSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSP 846 P P E+ FP + + + P V P P P +P Sbjct: 484 P-PGEIGFPGQPGAKGDRGLPGRDGVAGV-------------PGPQGTPGLIGQPGAKGE 529 Query: 847 PVPSWTELPSSGEES-----GAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGL-----PS 896 P + +L G++ G P ++G GS GH G + GL P Sbjct: 530 PGEFYFDLRLKGDKGDPGFPGQPGMTGR-AGSPGRDGHPGLPGPKGSPGSVGLKGERGPP 588 Query: 897 GDLDSSGLTSTVGSGLPVESGL--PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDL 954 G + G G P G P GD+ + +P P LP +G + L Sbjct: 589 GGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGP----KGEPGKIVPL 644 Query: 955 SGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL 1014 G P E L S G P G+ PG GLP GE PG+ G Sbjct: 645 PGPPGAEGLPGSPGFPG-----PQGD---RGFPGTPGRPGLP-GEKGAVGQPGI----GF 691 Query: 1015 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1074 P PG + + GLP G++ PG +GLP PGV+ G P Sbjct: 692 PG-------PPGPKGVDGLP-GDMGPPGTPGRPGFNGLPGN-------PGVQGQKGEPG- 735 Query: 1075 EVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGE 1132 PG++ + GLP PG + G+P GE PG++ I G P Sbjct: 736 ----VGLPGLKGLPGLPG----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPP 787 Query: 1133 VL--ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSG 1188 L +PGV I P G G +SG P GE PG+ D+ G P G Sbjct: 788 GLPGSVGSPGVPGIG--PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGL-DMPG-PKG 843 Query: 1189 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-----GEVLETAAPGVEDISGLP 1243 + PG+ SGLP G + APG+ G G + +PG GLP Sbjct: 844 DKGAQGLPGITGQSGLP-GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLP 902 Query: 1244 SGEVLETAAPGVEDISGLPS-----GEVLETAAPGVEDISGL-----------------P 1281 GE + PG G P G+V PG D + P Sbjct: 903 -GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGP 961 Query: 1282 SGEVLETTAPGVEEISGL-----------PSGEVLETTAPGVDEISGLPSGEVLETTAPG 1330 GE PG + G P G+ + PG + G P G V PG Sbjct: 962 IGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG-PKGSVGGMGLPG 1020 Query: 1331 VEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVS--------GVEDISGLPSGEVV 1382 G+P + S GD G+ + G + I+G P G Sbjct: 1021 TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFP-GSPG 1079 Query: 1383 ETSASGIEDVSELPSGEGLETSAS--GVEDLSRLPSGEEVLEISASGFGDLSGLPS--GG 1438 E G + +P GL+ S G LP E G L G+P G Sbjct: 1080 EKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG-----EKGDKGLPGLDGIPGVKGE 1134 Query: 1439 EGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPS-------------GKEDLVG- 1484 GL + G G +G+ SA G + GLP G + VG Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPGSA-GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193 Query: 1485 ---SASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS- 1540 + S + K G +G GLP G G + G P G P GLP Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP-GSPGHATEGPKGDRGPQGQPGLPGLPGP 1252 Query: 1541 ----GFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGL- 1595 G P + V +G G G I G P I+G + Sbjct: 1253 MGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG----ITGSKGDMG 1308 Query: 1596 PSGTELSGQASGSPDVSG--------EIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSG 1647 P G G P + G +PG G+ G P G P G L G G Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPP-GPPGPYDIIKGEPGLPG-PEG 1366 Query: 1648 QPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGA 1694 PG+ G L G P G ++G G+P P G+PGF GA Sbjct: 1367 PPGLKG-----LQGLPGPKGQQGVTGLV-GIPG----PPGIPGFDGA 1403 Score = 43.5 bits (101), Expect = 0.003 Identities = 81/291 (27%), Positives = 103/291 (35%), Gaps = 52/291 (17%) Query: 1616 PGLFGVSGQPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGTSQPFGITDLSG 1673 PG G +G+P G P T G T G SG + G PGI G+ G P GI +G Sbjct: 75 PGQKGDTGEP-GLPGTKG-TRGPPGASGYPGNPGLPGIPGQD-----GPPGPPGIPGCNG 127 Query: 1674 ETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEE 1733 T G G P GLPGF+G G P L G GE G V K E Sbjct: 128 -TKGERGPLGPP-GLPGFAG-NPGPPGL-PGMKGDPGEILG---------HVPGMLLKGE 174 Query: 1734 EGLGSVELSGLPSGEADLSGKSGMVDVSGQFS--------GTVDSSGFTSQTPEFSGLPS 1785 G + + P G L G G +G G G + Q P+ Sbjct: 175 RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234 Query: 1786 GIA---EVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGE 1842 G++ V G++ E G G G P + ++ E P + + Sbjct: 235 GVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKG--EPGKPGPRGKPGKD 292 Query: 1843 GPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGE-----PPGTP 1888 G G G+P GE G+ L G Q P GE PPG P Sbjct: 293 GDKG-------EKGSPGFPGE-PGYPGLIGRQG----PQGEKGEAGPPGPP 331 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 142 bits (357), Expect = 5e-33 Identities = 297/1130 (26%), Positives = 418/1130 (36%), Gaps = 209/1130 (18%) Query: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 P P PP P + +ESG P + G+ G+L G + GD SG + D Sbjct: 435 PGPPGPPSPEFETETLHNKESGFPGLRGE----QGPKGNLGLKG-IKGD--SGFCACD-- 485 Query: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTV-GELPS-GAEILEGSASGVGDLSGLP 958 G+ +T G P E G P G I P G+ S GA+ G+ VG L P Sbjct: 486 -GGVPNT---GPPGEPG-PPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG--P 538 Query: 959 SGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018 SG + + + G+P G+ ++ + G + G P + PG+ + GLP Sbjct: 539 SGPKGKKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPG----KDGVPGLPGLPGLPGDG 593 Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGV--EDISGLPSGEVLETTAPGVEDISGLPSGEV 1076 PG + + GLP GE PG+ + GLP L PG + GLP + Sbjct: 594 --GQGFPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQG 646 Query: 1077 LE----TTAPGVEDISGLPSGEVLETAAPGVEDISGLP--------SGEVLETAAPGVED 1124 L T P + S PSG PG + GLP SG E +PG+ Sbjct: 647 LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 706 Query: 1125 ISGLPS-----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1179 + LP GE PG+ GLP G + PG + +G G E APG Sbjct: 707 LPELPGFPGPRGEKGLPGFPGLPGKDGLP-GMIGSPGLPGSKGATGDIFG--AENGAPGE 763 Query: 1180 EDISGLP--SGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPG 1235 + + GL G + ++ PG++ + G P G E +PG G P G + G Sbjct: 764 QGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP-GTPGSSGPYG 822 Query: 1236 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295 ++ SGLP APG ISG P + G G P G +++ PG++ Sbjct: 823 IKGKSGLP-------GAPGFPGISGHPGKK-------GTRGKKG-PPGSIVKKGLPGLKG 867 Query: 1296 ISGLPSGEVLETTAPGVDEISGLPS--------GEVLETTAPGVEEISGLPSGEVLETST 1347 + G P G V +PG ++GLP+ G V PG+ + G+P L+ Sbjct: 868 LPGNP-GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIP 926 Query: 1348 SAVGDLSGLPSGGEVLEISVSGVEDISGLPS-----------GEVVETSASGIEDVSELP 1396 + G + G E G G+PS G+ ++G P Sbjct: 927 GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-P 985 Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLE-ISAS----GFGDLSGLPSGGEGLETSASEVGTD 1451 G+ E G L P +++ +S GF + GLP GL+ S+ G Sbjct: 986 RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLP----GLKGSSGITG-- 1039 Query: 1452 LSGLP--SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509 G+P SG +G+ S G SGLP K D +GQ E S Sbjct: 1040 FPGMPGESGSQGIRGS-PGLPGASGLPGLKGD--------------------NGQTVEIS 1078 Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569 G P P G P SGF D + + E G Sbjct: 1079 GSPG---------------PKGQPG----ESGFKGTKGRDGLIGNIGFPGNKGE---DGK 1116 Query: 1570 IGISGAGEISGLPSSELDISGRAS--GLPSGTELSGQAS--GSPDVSGE-----IPGLFG 1620 +G+SG + G P ++G GLP + G GSP + G PGL G Sbjct: 1117 VGVSGDVGLPGAPGFP-GVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1175 Query: 1621 VSGQPSGFPDTSGETS-GVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSG 1677 ++G P G T G +T + G +G PG GE G+ G G+ G+ G Sbjct: 1176 LNGLP-GTKGTHGTPGPSITGVPG-PAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD-RG 1232 Query: 1678 VPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT-------TF 1730 P L G P+GLPG G + +P L++G G +D P Sbjct: 1233 FPGLQG-PAGLPGAPGIS--LPSLIAGQPGDPGRPG----LDGERGRPGPAGPPGPPGPS 1285 Query: 1731 KEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEV 1790 + G G+P G G G+ SG G + G + P F G P + Sbjct: 1286 SNQGDTGDPGFPGIP-GPKGPKGDQGIPGFSG-LPGELGLKGMRGE-PGFMGTPGKVGPP 1342 Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850 G + P G+ G P PT EA + P G L L Sbjct: 1343 GDPGFPGMKGKAGPRGSSGLQGDPGQTPTA------------------EAVQVPPGPLGL 1384 Query: 1851 SGAHSGAPDMSGE--HSGFLDLSGLQS-----GLIEPSGEPPGTPYFSGD 1893 G G P ++G+ G + L G + G PSG PG P GD Sbjct: 1385 PGI-DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSG-LPGPPGALGD 1432 Score = 114 bits (285), Expect = 1e-24 Identities = 357/1372 (26%), Positives = 480/1372 (34%), Gaps = 301/1372 (21%) Query: 862 GAPDVSGDFTGSGD-VSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGLP 919 G P + G GD V F G + GD GLP D G+T G+ G P G P Sbjct: 146 GPPGLPGQKGSKGDPVLAPGSFKG-MKGD--PGLPGLD----GITGPQGAPGFPGAVG-P 197 Query: 920 SGDEERIEWPSTPTVGELPSGAEIL--EGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977 +G ++ P P P G L +G GD+ GLP G ++G + G P Sbjct: 198 AGPPG-LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDV-GLP-GPAGPPPSTGELEFMGFP 254 Query: 978 SGEVLETTAPGVED---ISGLPSGEVLETTAP----GVEDISGLPSGEVLETTAPGVEDI 1030 G+ PG + ISG P L TT G + I GLP G E + Sbjct: 255 KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPR----GPMGSEGV 310 Query: 1031 SGLPSGEVLETTA--PGVEDISGLPSGEVLETTAPGVE---DISG-LPSGEVLETTAPGV 1084 G P + + T PG+ G+ G+ + PG + DI G + SG + PGV Sbjct: 311 QGPPGQQGKKGTLGFPGLNGFQGI-EGQKGDIGLPGPDVFIDIDGAVISGNPGD---PGV 366 Query: 1085 EDISGLPSGEVLE-----TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA- 1138 + GL E ++ + PG+ +SG+P G + PG++ G P + A Sbjct: 367 PGLPGLKGDEGIQGLRGPSGVPGLPALSGVP-GALGPQGFPGLKGDQGNPGRTTIGAAGL 425 Query: 1139 ------PGVEDISGLPSGEV-------LETAAPGVEDISGLPSGEVLETAAPGVEDI--- 1182 PG G PS E E+ PG+ G P G + G Sbjct: 426 PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG-PKGNLGLKGIKGDSGFCAC 484 Query: 1183 -SGLPS-GEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVL 1229 G+P+ G E PG + GLP G APG+ G PSG Sbjct: 485 DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG-PSGPKG 543 Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289 + P + I G+P G+ ++ + G + G P + PG+ + GLP Sbjct: 544 KKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPGKD----GVPGLPGLPGLPGDG--GQG 596 Query: 1290 APGVEEISGLPSGEVLETTAPGV--DEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347 PG + + GLP GE PG+ + + GLP L PG + GLP + Sbjct: 597 FPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQ------ 645 Query: 1348 SAVGDLSGLP-SGGEVLEISVSGVEDISGLPS--GEVVETSASGIEDVSELPSGEGL--E 1402 GLP S G L + G SG P G + G+ P G E Sbjct: 646 -------GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE 698 Query: 1403 TSASGVEDLSRLPS-----GEEVLEISASGFGDLSGLPS--GGEGLETSASEVGTDLSGL 1455 + G+ L LP GE+ L G GLP G GL S G D+ G Sbjct: 699 PGSPGLVHLPELPGFPGPRGEKGLP-GFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGA 756 Query: 1456 PSGREGLE-----TSASGAEDLSGLPS-----GKEDLVGSASGDLDLGKLPSGTLGSGQA 1505 +G G + T G SGLP GK L+G P G GS Sbjct: 757 ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG-----------PKGERGSPGT 805 Query: 1506 PETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--GFPTVSLVDSTLVEVVTASTASE 1563 P G P GS P G+ SGLP GFP +S + Sbjct: 806 PGQVGQPG---------TPGSSGPYGIKGKSGLPGAPGFPGIS------------GHPGK 844 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVSGEIPGLFGV 1621 RG G G+ GLP + GLP L G + GSP V+G +P L G Sbjct: 845 KGTRGKKGPPGSIVKKGLPGLK--------GLPGNPGLVGLKGSPGSPGVAG-LPALSGP 895 Query: 1622 SGQPS-----GFPDTSG-----ETSGVTELSGLS-----SGQPGISGEASGVLYGTSQPF 1666 G+ GFP G T G+ + G + SG+ G GE G P Sbjct: 896 KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD--RGNPGPV 953 Query: 1667 GITD---------LSGE--------TSGVPDLSGQPS-----GLPGFSGATSGVPDLVSG 1704 GI L G+ ++G P G G PG GA G+P ++ G Sbjct: 954 GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKG 1012 Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGL----GSVELSGLPS-----------GEA 1749 + G P F GL GS ++G P G Sbjct: 1013 VSGKPG----------------PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSP 1056 Query: 1750 DLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809 L G SG+ + G TV+ SG +P G P GES G+ G Sbjct: 1057 GLPGASGLPGLKGDNGQTVEISG----SPGPKGQP-------GESGFK--GTKGRDGLIG 1103 Query: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLD 1869 G P + V + + AP G G+ + G G P SG H G + Sbjct: 1104 NIGFPGNKGEDGKVGVSGDVGLPGAP-------GFPGVAGMRG-EPGLPGSSG-HQGAIG 1154 Query: 1870 LSGLQSGLIEPSGEP-----------PGTPYFSG-DFASTTNVSGESSVAMGTSGEASGL 1917 G GLI P G P PGT G S T V G + + G GE G Sbjct: 1155 PLG-SPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLP-GPKGE-KGY 1211 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRP-PVTHTPQLFESSGKVSTAGDISG--ATPVLPG 1974 P + + +P + + G R P P + +S I+G P PG Sbjct: 1212 PGIG------IGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1265 Query: 1975 SGVE--------VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEAN 2026 E P SS + GF P+ + D G P S E Sbjct: 1266 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG---ELG 1322 Query: 2027 LERSSG-LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTA 2077 L+ G G G+ P + G++ G + G P TPTA Sbjct: 1323 LKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQ--GDPGQTPTA 1372 Score = 54.3 bits (129), Expect = 1e-06 Identities = 205/862 (23%), Positives = 276/862 (32%), Gaps = 209/862 (24%) Query: 1234 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGV 1293 PG I G P+G T + G+ + G E PG+ G P G+ PG Sbjct: 52 PGPIGIQG-PTGPQGFTGSTGLSGLKG-------ERGFPGLLGPYG-PKGDKGPMGVPGF 102 Query: 1294 EEISGLPS--GEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVG 1351 I+G+P G+ PG+D +G PG + GL L + G Sbjct: 103 LGINGIPGHPGQPGPRGPPGLDGCNGTQGA----VGFPGPDGYPGLLGPPGLPGQKGSKG 158 Query: 1352 DLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDL 1411 D P S G++ GLP + + +G + P G Sbjct: 159 DPVLAPG-------SFKGMKGDPGLPGLDGI----TGPQGAPGFPGAVG----------- 196 Query: 1412 SRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAED 1471 P+G L+ G L P G GL G +G E G Sbjct: 197 ---PAGPPGLQGPPGPPGPLG--PDGNMGL----------------GFQG-EKGVKGDVG 234 Query: 1472 LSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSG 1531 L G P+G ++G+L+ P G GS P G P G SG LG+ G Sbjct: 235 LPG-PAGPPP----STGELEFMGFPKGKKGSKGEPGPKGFP-GISGPPGFPGLGTTGEKG 288 Query: 1532 LPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591 G+P G P + + +GT+G G G+ + DI Sbjct: 289 EKGEKGIP-GLPGPR---GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDI--- 341 Query: 1592 ASGLP--------SGTELSGQ-----ASGSPDVSGE-----------IPGLFGVSG---- 1623 GLP G +SG G P + G+ +PGL +SG Sbjct: 342 --GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGA 399 Query: 1624 -QPSGFPDTSGE-------TSGVTELSG-------------------------LSSGQPG 1650 P GFP G+ T G L G SG PG Sbjct: 400 LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 459 Query: 1651 ISGEASGVLYGTSQPFGITDLSGET------SGVPDLS--GQPS--------GLPGFSGA 1694 + GE G G+ + G++ GVP+ G+P GLPG GA Sbjct: 460 LRGE-----QGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 514 Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754 D SG G + G+ L P K E L +++ G+P D SG Sbjct: 515 RG---DRGSGGAQGPAGAPGLV---GPLGPSGPKGKKGEPILSTIQ--GMPGDRGD-SGS 565 Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG-SSLPSGAYYGSGT 1813 G F G + G P GLP G+ G+ E G LP G Sbjct: 566 QG-------FRGVIGEPG-KDGVPGLPGLP-GLPGDGGQGFPGEKGLPGLPGEK--GHPG 614 Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGL 1873 P P L P +G G+ G P G + L + Sbjct: 615 PPGLPGNGLPG-------LPGPRGLPGDKGKDGL----PGQQGLPGSKG-----ITLPCI 658 Query: 1874 QSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTE 1933 G PSG PGTP F G S + G G+SG L+ + G Sbjct: 659 IPGSYGPSGF-PGTPGFPGPKGS-RGLPGTPG-QPGSSGSKGEPGSPGLVHLPELPGFPG 715 Query: 1934 PTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYP 1993 P + L P + GK G I +P LPGS + +E A Sbjct: 716 PRGEKGLPGFPGL---------PGKDGLPGMI--GSPGLPGSKGATGDI--FGAENGAPG 762 Query: 1994 EAGFGASAAPEASREDSGSPDL 2015 E G + DSG P L Sbjct: 763 EQGLQGLTGHKGFLGDSGLPGL 784 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 142 bits (357), Expect = 5e-33 Identities = 297/1130 (26%), Positives = 418/1130 (36%), Gaps = 209/1130 (18%) Query: 841 PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900 P P PP P + +ESG P + G+ G+L G + GD SG + D Sbjct: 434 PGPPGPPSPEFETETLHNKESGFPGLRGE----QGPKGNLGLKG-IKGD--SGFCACD-- 484 Query: 901 SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTV-GELPS-GAEILEGSASGVGDLSGLP 958 G+ +T G P E G P G I P G+ S GA+ G+ VG L P Sbjct: 485 -GGVPNT---GPPGEPG-PPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG--P 537 Query: 959 SGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018 SG + + + G+P G+ ++ + G + G P + PG+ + GLP Sbjct: 538 SGPKGKKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPG----KDGVPGLPGLPGLPGDG 592 Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGV--EDISGLPSGEVLETTAPGVEDISGLPSGEV 1076 PG + + GLP GE PG+ + GLP L PG + GLP + Sbjct: 593 --GQGFPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQG 645 Query: 1077 LE----TTAPGVEDISGLPSGEVLETAAPGVEDISGLP--------SGEVLETAAPGVED 1124 L T P + S PSG PG + GLP SG E +PG+ Sbjct: 646 LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 705 Query: 1125 ISGLPS-----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1179 + LP GE PG+ GLP G + PG + +G G E APG Sbjct: 706 LPELPGFPGPRGEKGLPGFPGLPGKDGLP-GMIGSPGLPGSKGATGDIFG--AENGAPGE 762 Query: 1180 EDISGLP--SGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPG 1235 + + GL G + ++ PG++ + G P G E +PG G P G + G Sbjct: 763 QGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP-GTPGSSGPYG 821 Query: 1236 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295 ++ SGLP APG ISG P + G G P G +++ PG++ Sbjct: 822 IKGKSGLP-------GAPGFPGISGHPGKK-------GTRGKKG-PPGSIVKKGLPGLKG 866 Query: 1296 ISGLPSGEVLETTAPGVDEISGLPS--------GEVLETTAPGVEEISGLPSGEVLETST 1347 + G P G V +PG ++GLP+ G V PG+ + G+P L+ Sbjct: 867 LPGNP-GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIP 925 Query: 1348 SAVGDLSGLPSGGEVLEISVSGVEDISGLPS-----------GEVVETSASGIEDVSELP 1396 + G + G E G G+PS G+ ++G P Sbjct: 926 GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-P 984 Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLE-ISAS----GFGDLSGLPSGGEGLETSASEVGTD 1451 G+ E G L P +++ +S GF + GLP GL+ S+ G Sbjct: 985 RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLP----GLKGSSGITG-- 1038 Query: 1452 LSGLP--SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509 G+P SG +G+ S G SGLP K D +GQ E S Sbjct: 1039 FPGMPGESGSQGIRGS-PGLPGASGLPGLKGD--------------------NGQTVEIS 1077 Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569 G P P G P SGF D + + E G Sbjct: 1078 GSPG---------------PKGQPG----ESGFKGTKGRDGLIGNIGFPGNKGE---DGK 1115 Query: 1570 IGISGAGEISGLPSSELDISGRAS--GLPSGTELSGQAS--GSPDVSGE-----IPGLFG 1620 +G+SG + G P ++G GLP + G GSP + G PGL G Sbjct: 1116 VGVSGDVGLPGAPGFP-GVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1174 Query: 1621 VSGQPSGFPDTSGETS-GVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSG 1677 ++G P G T G +T + G +G PG GE G+ G G+ G+ G Sbjct: 1175 LNGLP-GTKGTHGTPGPSITGVPG-PAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD-RG 1231 Query: 1678 VPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT-------TF 1730 P L G P+GLPG G + +P L++G G +D P Sbjct: 1232 FPGLQG-PAGLPGAPGIS--LPSLIAGQPGDPGRPG----LDGERGRPGPAGPPGPPGPS 1284 Query: 1731 KEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEV 1790 + G G+P G G G+ SG G + G + P F G P + Sbjct: 1285 SNQGDTGDPGFPGIP-GPKGPKGDQGIPGFSG-LPGELGLKGMRGE-PGFMGTPGKVGPP 1341 Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850 G + P G+ G P PT EA + P G L L Sbjct: 1342 GDPGFPGMKGKAGPRGSSGLQGDPGQTPTA------------------EAVQVPPGPLGL 1383 Query: 1851 SGAHSGAPDMSGE--HSGFLDLSGLQS-----GLIEPSGEPPGTPYFSGD 1893 G G P ++G+ G + L G + G PSG PG P GD Sbjct: 1384 PGI-DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSG-LPGPPGALGD 1431 Score = 114 bits (285), Expect = 1e-24 Identities = 357/1372 (26%), Positives = 480/1372 (34%), Gaps = 301/1372 (21%) Query: 862 GAPDVSGDFTGSGD-VSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGLP 919 G P + G GD V F G + GD GLP D G+T G+ G P G P Sbjct: 145 GPPGLPGQKGSKGDPVLAPGSFKG-MKGD--PGLPGLD----GITGPQGAPGFPGAVG-P 196 Query: 920 SGDEERIEWPSTPTVGELPSGAEIL--EGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977 +G ++ P P P G L +G GD+ GLP G ++G + G P Sbjct: 197 AGPPG-LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDV-GLP-GPAGPPPSTGELEFMGFP 253 Query: 978 SGEVLETTAPGVED---ISGLPSGEVLETTAP----GVEDISGLPSGEVLETTAPGVEDI 1030 G+ PG + ISG P L TT G + I GLP G E + Sbjct: 254 KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPR----GPMGSEGV 309 Query: 1031 SGLPSGEVLETTA--PGVEDISGLPSGEVLETTAPGVE---DISG-LPSGEVLETTAPGV 1084 G P + + T PG+ G+ G+ + PG + DI G + SG + PGV Sbjct: 310 QGPPGQQGKKGTLGFPGLNGFQGI-EGQKGDIGLPGPDVFIDIDGAVISGNPGD---PGV 365 Query: 1085 EDISGLPSGEVLE-----TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA- 1138 + GL E ++ + PG+ +SG+P G + PG++ G P + A Sbjct: 366 PGLPGLKGDEGIQGLRGPSGVPGLPALSGVP-GALGPQGFPGLKGDQGNPGRTTIGAAGL 424 Query: 1139 ------PGVEDISGLPSGEV-------LETAAPGVEDISGLPSGEVLETAAPGVEDI--- 1182 PG G PS E E+ PG+ G P G + G Sbjct: 425 PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG-PKGNLGLKGIKGDSGFCAC 483 Query: 1183 -SGLPS-GEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVL 1229 G+P+ G E PG + GLP G APG+ G PSG Sbjct: 484 DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG-PSGPKG 542 Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289 + P + I G+P G+ ++ + G + G P + PG+ + GLP Sbjct: 543 KKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPGKD----GVPGLPGLPGLPGDG--GQG 595 Query: 1290 APGVEEISGLPSGEVLETTAPGV--DEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347 PG + + GLP GE PG+ + + GLP L PG + GLP + Sbjct: 596 FPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQ------ 644 Query: 1348 SAVGDLSGLP-SGGEVLEISVSGVEDISGLPS--GEVVETSASGIEDVSELPSGEGL--E 1402 GLP S G L + G SG P G + G+ P G E Sbjct: 645 -------GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE 697 Query: 1403 TSASGVEDLSRLPS-----GEEVLEISASGFGDLSGLPS--GGEGLETSASEVGTDLSGL 1455 + G+ L LP GE+ L G GLP G GL S G D+ G Sbjct: 698 PGSPGLVHLPELPGFPGPRGEKGLP-GFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGA 755 Query: 1456 PSGREGLE-----TSASGAEDLSGLPS-----GKEDLVGSASGDLDLGKLPSGTLGSGQA 1505 +G G + T G SGLP GK L+G P G GS Sbjct: 756 ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG-----------PKGERGSPGT 804 Query: 1506 PETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--GFPTVSLVDSTLVEVVTASTASE 1563 P G P GS P G+ SGLP GFP +S + Sbjct: 805 PGQVGQPG---------TPGSSGPYGIKGKSGLPGAPGFPGIS------------GHPGK 843 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVSGEIPGLFGV 1621 RG G G+ GLP + GLP L G + GSP V+G +P L G Sbjct: 844 KGTRGKKGPPGSIVKKGLPGLK--------GLPGNPGLVGLKGSPGSPGVAG-LPALSGP 894 Query: 1622 SGQPS-----GFPDTSG-----ETSGVTELSGLS-----SGQPGISGEASGVLYGTSQPF 1666 G+ GFP G T G+ + G + SG+ G GE G P Sbjct: 895 KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD--RGNPGPV 952 Query: 1667 GITD---------LSGE--------TSGVPDLSGQPS-----GLPGFSGATSGVPDLVSG 1704 GI L G+ ++G P G G PG GA G+P ++ G Sbjct: 953 GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKG 1011 Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGL----GSVELSGLPS-----------GEA 1749 + G P F GL GS ++G P G Sbjct: 1012 VSGKPG----------------PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSP 1055 Query: 1750 DLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809 L G SG+ + G TV+ SG +P G P GES G+ G Sbjct: 1056 GLPGASGLPGLKGDNGQTVEISG----SPGPKGQP-------GESGFK--GTKGRDGLIG 1102 Query: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLD 1869 G P + V + + AP G G+ + G G P SG H G + Sbjct: 1103 NIGFPGNKGEDGKVGVSGDVGLPGAP-------GFPGVAGMRG-EPGLPGSSG-HQGAIG 1153 Query: 1870 LSGLQSGLIEPSGEP-----------PGTPYFSG-DFASTTNVSGESSVAMGTSGEASGL 1917 G GLI P G P PGT G S T V G + + G GE G Sbjct: 1154 PLG-SPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLP-GPKGE-KGY 1210 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRP-PVTHTPQLFESSGKVSTAGDISG--ATPVLPG 1974 P + + +P + + G R P P + +S I+G P PG Sbjct: 1211 PGIG------IGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1264 Query: 1975 SGVE--------VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEAN 2026 E P SS + GF P+ + D G P S E Sbjct: 1265 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG---ELG 1321 Query: 2027 LERSSG-LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTA 2077 L+ G G G+ P + G++ G + G P TPTA Sbjct: 1322 LKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQ--GDPGQTPTA 1371 Score = 54.3 bits (129), Expect = 1e-06 Identities = 205/862 (23%), Positives = 276/862 (32%), Gaps = 209/862 (24%) Query: 1234 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGV 1293 PG I G P+G T + G+ + G E PG+ G P G+ PG Sbjct: 51 PGPIGIQG-PTGPQGFTGSTGLSGLKG-------ERGFPGLLGPYG-PKGDKGPMGVPGF 101 Query: 1294 EEISGLPS--GEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVG 1351 I+G+P G+ PG+D +G PG + GL L + G Sbjct: 102 LGINGIPGHPGQPGPRGPPGLDGCNGTQGA----VGFPGPDGYPGLLGPPGLPGQKGSKG 157 Query: 1352 DLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDL 1411 D P S G++ GLP + + +G + P G Sbjct: 158 DPVLAPG-------SFKGMKGDPGLPGLDGI----TGPQGAPGFPGAVG----------- 195 Query: 1412 SRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAED 1471 P+G L+ G L P G GL G +G E G Sbjct: 196 ---PAGPPGLQGPPGPPGPLG--PDGNMGL----------------GFQG-EKGVKGDVG 233 Query: 1472 LSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSG 1531 L G P+G ++G+L+ P G GS P G P G SG LG+ G Sbjct: 234 LPG-PAGPPP----STGELEFMGFPKGKKGSKGEPGPKGFP-GISGPPGFPGLGTTGEKG 287 Query: 1532 LPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591 G+P G P + + +GT+G G G+ + DI Sbjct: 288 EKGEKGIP-GLPGPR---GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDI--- 340 Query: 1592 ASGLP--------SGTELSGQ-----ASGSPDVSGE-----------IPGLFGVSG---- 1623 GLP G +SG G P + G+ +PGL +SG Sbjct: 341 --GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGA 398 Query: 1624 -QPSGFPDTSGE-------TSGVTELSG-------------------------LSSGQPG 1650 P GFP G+ T G L G SG PG Sbjct: 399 LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 458 Query: 1651 ISGEASGVLYGTSQPFGITDLSGET------SGVPDLS--GQPS--------GLPGFSGA 1694 + GE G G+ + G++ GVP+ G+P GLPG GA Sbjct: 459 LRGE-----QGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 513 Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754 D SG G + G+ L P K E L +++ G+P D SG Sbjct: 514 RG---DRGSGGAQGPAGAPGLV---GPLGPSGPKGKKGEPILSTIQ--GMPGDRGD-SGS 564 Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG-SSLPSGAYYGSGT 1813 G F G + G P GLP G+ G+ E G LP G Sbjct: 565 QG-------FRGVIGEPG-KDGVPGLPGLP-GLPGDGGQGFPGEKGLPGLPGEK--GHPG 613 Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGL 1873 P P L P +G G+ G P G + L + Sbjct: 614 PPGLPGNGLPG-------LPGPRGLPGDKGKDGL----PGQQGLPGSKG-----ITLPCI 657 Query: 1874 QSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTE 1933 G PSG PGTP F G S + G G+SG L+ + G Sbjct: 658 IPGSYGPSGF-PGTPGFPGPKGS-RGLPGTPG-QPGSSGSKGEPGSPGLVHLPELPGFPG 714 Query: 1934 PTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYP 1993 P + L P + GK G I +P LPGS + +E A Sbjct: 715 PRGEKGLPGFPGL---------PGKDGLPGMI--GSPGLPGSKGATGDI--FGAENGAPG 761 Query: 1994 EAGFGASAAPEASREDSGSPDL 2015 E G + DSG P L Sbjct: 762 EQGLQGLTGHKGFLGDSGLPGL 783 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 133 bits (334), Expect = 2e-30 Identities = 317/1151 (27%), Positives = 396/1151 (34%), Gaps = 246/1151 (21%) Query: 828 EPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHL------- 880 EP +P A P PS P P P S + +G + SG + G + G + Sbjct: 163 EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222 Query: 881 --DFSGQLSGDRASGLPSGDLDSSGLTSTVGS-------GLPVESGLP--SGDEERIEWP 929 GQ G +G P G+ G +GS G P E G P +G+ + + Sbjct: 223 PQGLQGQQGGAGPTG-PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281 Query: 930 STPTVGELPSGAEILEG--SASGVGDLSGLPSGEVLETSASG----------VGDLS--G 975 +P P GA L G G L G P GEV + G +G L G Sbjct: 282 GSPGARGFP-GAPGLPGLKGHRGHKGLEG-PKGEVGAPGSKGEAGPTGPMGAMGPLGPRG 339 Query: 976 LPS--GEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLP--SGEVLETTAPGVED 1029 +P G + APG G+P G + PG G P GE T A G E Sbjct: 340 MPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEG 399 Query: 1030 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS-----GEVLETTAPGV 1084 P G+ ET PG GLP G + PG + +G P G +PG Sbjct: 400 ----PQGQRGETGPPGPVGSPGLP-GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454 Query: 1085 EDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGL--PSGEVLETAAPG 1140 + +G P G + PGV G P GE PG I G P GE + G Sbjct: 455 QGSTG-PQGIRGQPGDPGVPGFKGEAGPKGE------PGPHGIQGPIGPPGEEGKRGPRG 507 Query: 1141 VEDISGLPSGEVLETAAPGVEDI---SGLP--------------SGEVLETAAPGVEDIS 1183 G P G V E APG GLP SG PG Sbjct: 508 DPGTVG-PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566 Query: 1184 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1243 GLP L T PGV+ P G++ APG + G P G + PG + G P Sbjct: 567 GLPGARGL-TGNPGVQG----PEGKLGPLGAPGEDGRPG-PPGSIGIRGQPGSMGLPG-P 619 Query: 1244 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGE 1303 G + PG +G+P + APG + G PSG V PG+ +GE Sbjct: 620 KGSSGDPGKPGEAGNAGVPG----QRGAPGKDGEVG-PSGPV---GPPGL-------AGE 664 Query: 1304 VLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVL 1363 E PG GLP PG G P + + AVG L G Sbjct: 665 RGEQGPPGPTGFQGLPG-------PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPG 717 Query: 1364 EISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGLETSASGVEDLSRLPSGEEVL 1421 E G I+GLP GE G + S PSG +T G++ + GE + Sbjct: 718 E---RGEPGITGLP-GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM----PGERGI 769 Query: 1422 EISASGFGDLSGLPSGGEGLETSASEVGTDLSGL--------PSGREGLETSASGAEDLS 1473 + GD G+ G +G E +A G GL P+G G E G L Sbjct: 770 AGTPGPKGDRGGI--GEKGAEGTAGNDGA--RGLPGPLGPPGPAGPTG-EKGEPGPRGLV 824 Query: 1474 GLPSGKEDLVGSASGDLDLGKLP-SGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGL 1532 G P G GS + G + +G G P G P G G+ D GS P GL Sbjct: 825 G-PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP-GEPGQKG--DAGSPGPQGL 880 Query: 1533 PDFSGL--PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISG 1590 G P+G P + GRGT G GA +G P S +G Sbjct: 881 AGSPGPHGPNGVPGLK------------------GGRGTQGPPGA---TGFPGS----AG 915 Query: 1591 RASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQ--------PSGFPDTSGETSGVTE 1640 R G P G A G P G PGL G G P+G P G+ E Sbjct: 916 RV-GPPGPAGAPGPAGPLGEPGKEGP-PGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGE 973 Query: 1641 LSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETS--GVPDLSGQPSGLPGFSGATSGV 1698 GQPG G GT+ GI + G+ G+P L G P+G PG G T Sbjct: 974 -----DGQPGPDGPPGPA--GTTGQRGIVGMPGQRGERGMPGLPG-PAGTPGKVGPTGAT 1025 Query: 1699 PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMV 1758 D G S+G P EG P+G G+ G V Sbjct: 1026 GDKGPPGPVGPPGSNG------------PVGEPGPEG---------PAGNDGTPGRDGAV 1064 Query: 1759 DVSGQF-----SGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGT 1813 G +G S G TP G P + SR IG P G G Sbjct: 1065 GERGDRGDPGPAGLPGSQG-APGTPGPVGAPGDAGQRGDPGSRGPIG---PPGRAGKRGL 1120 Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGE-HSGFLDLSG 1872 P GP G G H D + H GF L G Sbjct: 1121 P----------------------------GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152 Query: 1873 LQSGLIEPSGE 1883 L G P+GE Sbjct: 1153 L-PGPPGPNGE 1162 Score = 97.4 bits (241), Expect = 1e-19 Identities = 264/986 (26%), Positives = 335/986 (33%), Gaps = 199/986 (20%) Query: 748 PVGTSPLPGILPTWPPTGA---ATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEE 804 PVG+ LPG + T GA T GP + P S P S P P + Sbjct: 412 PVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP-QGIRGQPGDP 470 Query: 805 PFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSAS------EEPYTPSPPVPSWTELPSSG 858 P + E P EP P P P +P T PP P Sbjct: 471 GVPGFKG----EAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV-------- 518 Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917 E GAP G F GS + G G+ G + SSG + G G P E G Sbjct: 519 GERGAPGNRG-FPGSDGLPGPKGAQGE----------RGPVGSSGPKGSQGDPGRPGEPG 567 Query: 918 LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977 LP GA L G+ G P G++ A G G P Sbjct: 568 LP--------------------GARGLTGNPGVQG-----PEGKLGPLGAPGEDGRPG-P 601 Query: 978 SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1037 G + PG + G P G + PG +G+P + APG + G PSG Sbjct: 602 PGSIGIRGQPGSMGLPG-PKGSSGDPGKPGEAGNAGVPG----QRGAPGKDGEVG-PSGP 655 Query: 1038 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPS--- 1092 V PG+ +GE E PG GLP G E PG + + G P Sbjct: 656 V---GPPGL-------AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705 Query: 1093 -----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDIS 1145 GE G I+GLP GE G + G PSG +T PG++ Sbjct: 706 PLGPRGERGNPGERGEPGITGLP-GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ--- 761 Query: 1146 GLPSGEVLETAAPGVE-DISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1204 G+P GE PG + D G+ GE G + GLP PG Sbjct: 762 GMP-GERGIAGTPGPKGDRGGI--GEKGAEGTAGNDGARGLPG----PLGPPG------- 807 Query: 1205 PSGEVLETAAPGVEDISGLPS--------GEVLETAAPGVEDISGLPSGEVLETAAPGVE 1256 P+G E PG + G P GE T A G G P G+ PGV+ Sbjct: 808 PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG-PDGQ------PGVK 860 Query: 1257 DISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEIS 1316 G P G+ + +PG + ++G P G + GL G + G + Sbjct: 861 GEPGEP-GQKGDAGSPGPQGLAGSPGPH-------GPNGVPGLKGGRGTQ----GPPGAT 908 Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLP-SGGEVLEISVSGVEDISG 1375 G P G PG G P+G + E L G P S G V + +G Sbjct: 909 GFP-GSAGRVGPPGPAGAPG-PAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG------ 960 Query: 1376 LPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPS--GEEVLEISASGFGDLSG 1433 P G + G ED P G +G + +P GE + G Sbjct: 961 -PPGGPGDKGDPG-EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018 Query: 1434 L-PSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492 + P+G G + VG S P G G E A G P G++ VG D Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN----DGTP-GRDGAVGERGDRGDP 1073 Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEY-SGVDLGSGPPSGLPDFSGLPSGFPTVSLVDST 1551 G P+G GS AP T G P G G+ D GS P G P +G G P Sbjct: 1074 G--PAGLPGSQGAPGTPG-PVGAPGDAGQRGDPGSRGPIGPPGRAG-KRGLPGPQ----- 1124 Query: 1552 LVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDV 1611 + RG G G +GL GLP +G+ Sbjct: 1125 ----GPRGDKGDHGDRGDRGQKGHRGFTGL-----------QGLPGPPGPNGEQG----- 1164 Query: 1612 SGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDL 1671 S IPG FG G P G SG+ L + G PG+ G G + P G Sbjct: 1165 SAGIPGPFGPRG-PPGPVGPSGKEGNPGPLGPI--GPPGVRGSV-----GEAGPEG---- 1212 Query: 1672 SGETSGVPDLSGQPSGLPGFSGATSG 1697 G P G P G PG A G Sbjct: 1213 ---PPGEPGPPG-PPGPPGHLTAALG 1234 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 128 bits (321), Expect = 8e-29 Identities = 376/1652 (22%), Positives = 596/1652 (36%), Gaps = 277/1652 (16%) Query: 708 GVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS-------PLPGI--- 757 G A + +T++V +G+TT + +T + P + +S PLP Sbjct: 1468 GQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLS 1527 Query: 758 ---------LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP- 807 LP P+ A+T ++T P ++ +P V PS + P P Sbjct: 1528 SASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPV 1587 Query: 808 ---------SVRPFPSVELFPSEEPFPSKEPSP-SEEPSASEEPYTPSP----------- 846 P P PS P P ++ SAS TP P Sbjct: 1588 TDTSSASKGDTTPLPVTS--PSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGH 1645 Query: 847 PVPSWTELPSSGEESGAPDVSGDFTGSGDVSGH---LDFSGQLSG--DRASGLPSGDLDS 901 P PSS A + T S +GH L +G S D + LP D+ S Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSSAS-TGHATPLPVTGLSSATTDDTTRLPVTDVSS 1704 Query: 902 SGLTSTVGSGLPVESGLPSGDEE--RIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959 + + S + +GD + PS+ + G S + + S++ G + LP Sbjct: 1705 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH-ASPLLVTDASSASTGQATPLPV 1763 Query: 960 GEVLETSASGVGDL--SGLPSGEVLETTAPGVEDISGLPSGEV--LETTAPGVEDISGLP 1015 + S + L +GL S +TT V D+S +G+ L T+P Sbjct: 1764 TDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTT 1823 Query: 1016 SGEVLETTAPGVEDISGLP-----SGEVLETTAPGVEDISGLPSGE-----VLETTAPGV 1065 V + ++ D + LP S TT+ V D S + +G V + ++ Sbjct: 1824 PLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883 Query: 1066 EDISGLP-----SGEVLETTAPGVEDISGLPSGE-----VLETAAPGVEDISGLP----- 1110 D + LP S +TT V D S + +G V ++ D + LP Sbjct: 1884 GDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPS 1943 Query: 1111 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE 1170 S T V D S +P+G T+ P V D S + +G T P V D S + +G Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHA--TSLP-VTDASSVSTGHA--TPLP-VTDASSVSTGH 1997 Query: 1171 VLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1230 T P V D S + +G+ T P ++ L S +T V D S +G+ + Sbjct: 1998 A--TPLP-VTDTSSVSTGQA--TPLP----VTSLSSASTGDTTPLPVTDTSSASTGQ--D 2046 Query: 1231 TAAPGVEDISGLPSGEV--LETAAPG-----------VEDISGLPSGEVLETAAPGVEDI 1277 T P V +S + +G+ L +P V D S + +G V D Sbjct: 2047 TPLP-VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLL---VTDA 2102 Query: 1278 SGLPSGEVLETTAPGVEEISGLPSGEV--LETTAPGVDEISGLPSGEVLETTAPGVEEIS 1335 S + +G TA V + S L +G+ L T+P V +T++ + Sbjct: 2103 SSVSTG---HATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHAT 2159 Query: 1336 GLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSEL 1395 LP V +TS+++ G + LP V + S + + LP V +TS++ + L Sbjct: 2160 SLP---VTDTSSASTGHATSLP----VTDTSSASTGHATPLP---VTDTSSASTGQATPL 2209 Query: 1396 PSGEGLETSASG-----VEDLSRLPSGE----EVLEISASGFGDLSGLP-------SGGE 1439 P S V D S +G+ V +S++ GD + LP S G Sbjct: 2210 PVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGH 2269 Query: 1440 GLE---TSASEVGT-DLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKL 1495 TS S V T D + LP TS S A P D +++G L Sbjct: 2270 ATSLPVTSLSSVSTGDTTPLP------VTSPSSASTGHATPLHVTDASSASTGHAT--PL 2321 Query: 1496 PSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEV 1555 P +L S +T+ LP S G P + D S + +G D+T + V Sbjct: 2322 PVTSLSSASTGDTTPLP---VTSPSSASTGHATPLHVTDASSVSTG-------DTTPLPV 2371 Query: 1556 VTASTASELEGRGT------IGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSP 1609 ++S+AS G T + G+ + LP + D S ++G + ++G +S S Sbjct: 2372 TSSSSAS--SGHTTPLPVTDASSASTGDTTPLPVT--DTSSASTGHATHLPVTGLSSAST 2427 Query: 1610 DVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGIT 1669 + +P + VS +G TS + +G ++ PG + S V G + P +T Sbjct: 2428 GDTTRLP-VTNVSSASTGHATPLPVTSTSSASTGDTTPLPGT--DTSSVSTGHTTPLLVT 2484 Query: 1670 DLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGS-GESSGITFVDTSLVEVAPT 1728 D S ++G D + P P + P V+ T S S G+++ + + S + Sbjct: 2485 DASSVSTG--DTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHA 2542 Query: 1729 T---FKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPS 1785 T + + LP + + +G S + S+G T+ P + Sbjct: 2543 TSLHVTSPSSASTGHATSLPVTDTS-AASTGHATPLPVTSTSSASTGDTTPLPVTDTYSA 2601 Query: 1786 GIAEVS----GESSRAEIGSSLP------SGAYYGSGTPSSFPTVSLVD--RTLVESVTQ 1833 + + ++S A G + P S A G TP S V VT Sbjct: 2602 STGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTS 2661 Query: 1834 APTAQEAGEGPSGILELSGAHSG------APDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887 +A P + + S +G D S +G + SG Sbjct: 2662 PSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPL 2721 Query: 1888 PYFSGDFASTTN-----VSGESSVAMG-------------TSGEASGLPEVTLITSEFVE 1929 P ST + V+ SSV+ G ++G A+ LP +L S Sbjct: 2722 PVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSL--SSVST 2779 Query: 1930 GVTEP-----TISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPE 1984 G T P T S GQ P+ T S VST G T LP + +S Sbjct: 2780 GDTTPLPVTDTSSASTGQATPLPVT-----SLSSVST-----GDTTPLPVTDTSSASTGH 2829 Query: 1985 SSSETSAYPEAGFGASAAP----EASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 ++S + A P + S +G L T A++ ++ L V+ T Sbjct: 2830 ATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDT-SSASIGHATSLPVT-DTS 2887 Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI- 2099 + G A+ S S +T ATP D + S +GH + L V Sbjct: 2888 SISTGHATPLHVTSPSSASTG----------HATPLPVTDTSSAS---TGHANPLHVTSP 2934 Query: 2100 -------STSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDAS----- 2147 +T +P ++ T T L + S S + +G+ T TSP+ AS Sbjct: 2935 SSASTGHATPLPVTD-TSSASTGHATPLPVTSLSSVSTGDTTPL--PVTSPSSASTGHTT 2991 Query: 2148 -IPASPEWKRESESTAAAPARSCAEEPCGAGT 2178 +P + + A P S + G T Sbjct: 2992 PLPVTDTSSASTGQATALPVTSTSSASTGDTT 3023 Score = 112 bits (281), Expect = 3e-24 Identities = 358/1586 (22%), Positives = 570/1586 (35%), Gaps = 235/1586 (14%) Query: 717 ETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPS 776 +TT +P +T+++ T P T+ T T LP P+ A+T +T P Sbjct: 2461 DTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTR-----LPVTSPSSASTGHTTPLP- 2514 Query: 777 ATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELF-PSEEPFPSKEPSPSEEP 835 T+ PSAS + P P S S R S+ + PS P + Sbjct: 2515 VTDTPSAS---TGDTTPLPVTNASSL-----STRHATSLHVTSPSSASTGHATSLPVTDT 2566 Query: 836 SASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP 895 SA+ + PV S T S+G+ + P V+ ++ S + L + S P Sbjct: 2567 SAASTGHATPLPVTS-TSSASTGDTTPLP-VTDTYSASTGQATPLPVTDTSSASTGDTTP 2624 Query: 896 SGDLDSSGLTSTVGSGLPVE--SGLPSGDEE--RIEWPSTPTVGELPSGAEILEGSASGV 951 D+S ++ + LPV S + +G + PS+ + G + + + S+ Sbjct: 2625 LPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHT-TPLPVTDASSVST 2683 Query: 952 GDLSGLPSGEVLETSASGVGDLSGLP-----SGEVLETTAPGVEDISGLPSGEVLETTAP 1006 G + LP V + S+ G + LP S TT V D S + +G T+ Sbjct: 2684 GHATSLP---VTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHA---TSL 2737 Query: 1007 GVEDISGLPSGEVLETTAPGVEDIS----------GLPSGEVLETTAPGVEDISGLPSGE 1056 V D S + +G +S L S +TT V D S +G+ Sbjct: 2738 PVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQ 2797 Query: 1057 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE-----VLETAAPGVEDISGLPS 1111 T V +S + +G+ TT V D S +G V +T++ + LP Sbjct: 2798 A---TPLPVTSLSSVSTGD---TTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPD 2851 Query: 1112 GEVLETAAPG------VEDISGLPSGEVLETAAPGVEDISGLPSGEV--LETAAPG---- 1159 + +A+ G V D S G T+ P V D S + +G L +P Sbjct: 2852 TDT-SSASTGHATLLPVTDTSSASIGHA--TSLP-VTDTSSISTGHATPLHVTSPSSAST 2907 Query: 1160 -------VEDISGLPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1210 V D S +G L +P V +T++ + LP V Sbjct: 2908 GHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLP---VT 2964 Query: 1211 ETAAPGVEDISGLP-----SGEVLETAAPGVEDISGLPSGE-----VLETAAPGVEDISG 1260 ++ D + LP S T V D S +G+ V T++ D + Sbjct: 2965 SLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTP 3024 Query: 1261 LPSGEVLETAAPG------VEDISGLPSGEV--LETTAPGVEE--------ISGLPSGEV 1304 LP + +A+ G V +S + +G+ L T+P ++ S Sbjct: 3025 LPVTDT-SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSAST 3083 Query: 1305 LETTAPGVDEISGLPSGEV--LETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEV 1362 + T V +S + +G+ L T+P S V +TS+++ GD + LP V Sbjct: 3084 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLP----V 3139 Query: 1363 LEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASG-----VEDLSRLPSG 1417 + S + D + LP V +TS+S D + L E S V D S +G Sbjct: 3140 TDTSSAYTGDTTSLP---VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTG 3196 Query: 1418 E----EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLS 1473 V S++ GD + +P T S V T P GL ++++G D + Sbjct: 3197 HATPLHVTSPSSASTGDTTPVP------VTDTSSVSTG-HATPLPVTGLSSASTG--DTT 3247 Query: 1474 GLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLP 1533 LP D+ +++G LP S +T LP S G P + Sbjct: 3248 RLP--VTDISSASTGQAT--PLPVTNTSSVSTGDTMPLP---VTSPSSASTGHATPLPVT 3300 Query: 1534 DFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRAS 1593 S +G T V ST +T + + + G+ + LP + + Sbjct: 3301 STSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSS---ASTGDTTPLPVTSPSSASTGH 3357 Query: 1594 GLPSGTELSGQASGSPDVSGEIPGLFGVS---GQPSGFPDTSGETSG------VTELSGL 1644 P + AS + + G S P DTS ++G VT LS + Sbjct: 3358 TTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSV 3417 Query: 1645 SSGQ--PGISGEASGVLYGTSQPFGITDLSGETSG------VPDLSGQPSGLPGFSGATS 1696 S+G P +AS G + P +T LS ++G V D S +G Sbjct: 3418 STGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTG--------H 3469 Query: 1697 GVPDLVSGTTSGS-GESSGITFVDTSLVEVAPTTFKEEEGLGSVELSG-LPSGEADLSGK 1754 P V+ T+S S G+++ + DTS T L SV P D S Sbjct: 3470 ATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSV 3529 Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTP 1814 S +G + + ++ T + + LP + + ++PS + G TP Sbjct: 3530 S-----TGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTP 3584 Query: 1815 SSFPTVSLVDRTLVE--SVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFL---D 1869 + S V V VT +A P + S A +G H+ L D Sbjct: 3585 LPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTG-------HATPLLVTD 3637 Query: 1870 LSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVE 1929 S + +G P P T S TT + + + ++G+A+ LP +L S Sbjct: 3638 ASSVSTGHATPL---PVTDASSASTGDTTPLP-VTDTSSASTGQATPLPVTSL--SSVST 3691 Query: 1930 GVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSET 1989 G T P + TP VST G T LP + P S+S Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVST-----GDTMPLPVTS------PSSASTG 3740 Query: 1990 SAYPEAGFGASAAPEASREDSGSPDLSETTSAF--HEANLERSSGLGVS-GSTLTFQEGE 2046 A P G S+ AS D+ +++T+SA H L + S T + Sbjct: 3741 HATPLPVTGLSS---ASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTD 3797 Query: 2047 ASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI------- 2099 S+A +G +T T + TP D + +S +GH + L V Sbjct: 3798 VSSAS--TGHATPLPVTSTSSASTGDTTPLPVTDTSSVS---TGHATSLPVTSRSSASTG 3852 Query: 2100 -STSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDAS------IPASP 2152 +T +P ++ T T L + S+S + +G T TSP+ AS +P + Sbjct: 3853 HATPLPVTD-TSSVSTGHATPLPVTSTSSVSTGHATPL--PVTSPSSASTGHATPVPVTS 3909 Query: 2153 EWKRESESTAAAPARSCAEEPCGAGT 2178 + T P + + G T Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHAT 3935 Score = 96.7 bits (239), Expect = 3e-19 Identities = 329/1588 (20%), Positives = 554/1588 (34%), Gaps = 242/1588 (15%) Query: 693 SPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752 +PS + +V V+A+ E T S TT L TT QT+W Sbjct: 520 NPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTT--LPKTTGAGAQTQWTQE------- 570 Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPF 812 TG E PS + SPS P S PS Sbjct: 571 -----------TGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPST--- 616 Query: 813 PSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTG 872 + S SP E P+ S+ + T+ P + +ES T Sbjct: 617 -------NHSTIHSTSTSPQESPAVSQRGH---------TQAPQTTQESQTTRSVSPMTD 660 Query: 873 SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPST- 931 + V+ S SG S + D + +T P+GD + P+T Sbjct: 661 TKTVTTP-GSSFTASGHSPSEIVPQDAPTISAATTFAPA-------PTGDGHTTQAPTTA 712 Query: 932 ---------PTVGELPSGAEILEGS-----ASGVGDLSGLPSGEVLETSASGVGD-LSGL 976 T+G PSG L + A+ V G P G+ SAS D + + Sbjct: 713 LQAAPSSHDATLG--PSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAM 770 Query: 977 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1036 E+T + + P+ TT+ G S S TT G E IS SG Sbjct: 771 THTHQAESTEASGQTQTSEPASSGSRTTSAGTATPS---SSGASGTTPSGSEGIS--TSG 825 Query: 1037 EVLE-TTAPGVEDISGLPSGEVLETTAP--GVEDISGLPSGEVLETTAPGVEDIS--GLP 1091 E ++ P + + + E+L +A + +G+ S V T P + + S G P Sbjct: 826 ETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRP 885 Query: 1092 SGEVLETAAPGVEDISGLPSGEVLETAA----PGVEDISGLPSGEVLETAAPGVEDISGL 1147 +G+ T+ PS ETAA + + + A+ + S + Sbjct: 886 TGQSSPTS----------PSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTV 935 Query: 1148 PSGEVLETA----APGVEDISGLPSGEVLETAAPGVEDISGLP-----SGEVLETAAPGV 1198 P T+ +P E + PSG + + + LP S T V Sbjct: 936 PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHV 995 Query: 1199 EDISGLPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVE 1256 D S + +G L +P V +T++ ++ LP V ++ Sbjct: 996 TDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP---VTSFSSASTG 1052 Query: 1257 DISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEIS 1316 D + LP V +T++ ++ LP V ++ + + LP V +T++ + Sbjct: 1053 DSTPLP---VTDTSSASTGHVTPLP---VTSLSSASTGDTTPLP---VTDTSSASTGHAT 1103 Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLP-------SGGEVLEISVSG 1369 LP V +T++ + LP V +TS+++ G + LP S G + V+ Sbjct: 1104 SLP---VTDTSSVSTGHTTPLP---VTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVT- 1156 Query: 1370 VEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFG 1429 D S +G+ + + VS + TS S P V + S++ G Sbjct: 1157 --DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL--LVTDTSSASTG 1212 Query: 1430 DLSGLPSGGEGLETSASEVGTDLS-----GLPSGREGLETSASGAEDLSGLPSGK-EDLV 1483 + LP T AS V TD + +PS T+ D S +G+ L+ Sbjct: 1213 HATPLP------VTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLL 1266 Query: 1484 GSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFP 1543 + + + G + S + T + S G P + S +G Sbjct: 1267 VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG-- 1324 Query: 1544 TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSG 1603 D+ + V + S+AS G+ + LP + D S ++G + ++ Sbjct: 1325 -----DTMPLPVTSPSSAS------------TGDTTPLPVT--DASSVSTGHTTPLHVTD 1365 Query: 1604 QASGSPDVSGEIPGLFGVSGQPSGFPDTS------GETS--GVTELSGLSSGQ--PGISG 1653 +S S +GQ + P TS G+T+ VT S S+G P + Sbjct: 1366 ASSAS-------------TGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 1412 Query: 1654 EASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGS-GES 1712 + S G + P +TD S ++ + P +P + P V+ T+S S G++ Sbjct: 1413 DTSSASTGHATPLPVTDASSVST--DHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQA 1470 Query: 1713 SGITFVDTSLVEVA-----PTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGT 1767 + + DTS V P T G V + S + +G + + V+ S + Sbjct: 1471 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSAS 1530 Query: 1768 VD-------SSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTV 1820 +S ++ T + + LP A + + PS A G TP Sbjct: 1531 TGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDT 1590 Query: 1821 SLVDR--TLVESVTQAPTAQEAGEGPSGILELSGAHSG---------APDMSGEHSGFLD 1869 S + T VT +A P + + S A +G A +S H+ L Sbjct: 1591 SSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLH 1650 Query: 1870 LSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS--GESSVAMGTSGEASGLPEVTLITSEF 1927 ++ S +G P S AST + + + ++ T+ + + LP + ++ Sbjct: 1651 VTSPSSA---STGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAST 1707 Query: 1928 VEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGD--ISGATPVLPGSGVEVSSVPES 1985 + P S T P SS A ++ A+ G + S Sbjct: 1708 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTS 1767 Query: 1986 SSETS-AYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQE 2044 S T+ A P G S+ AS +D+ +++ +SA + S ST Sbjct: 1768 SVSTAHATPLPVTGLSS---ASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAST----- 1819 Query: 2045 GEASAAPEVSGESTTTSDVGTEAPGLPSATP---TASGDRTEISGDLSGHTSQLGVVIST 2101 G+ + P S +T D + +PS+ T S T+ S +GH + L V ++ Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDAS 1879 Query: 2102 SIPESEW-------TQQTQRPAETHLEIESSSLLYSGEETH----TVETATSPTDASIPA 2150 S+ + T T L + +S + +G T ++ +A++ +P Sbjct: 1880 SVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPV 1939 Query: 2151 SPEWKRESESTAAAPARSCAEEPCGAGT 2178 + S T P + P G T Sbjct: 1940 TSPSSASSGHTTPLPVTDASSVPTGHAT 1967 Score = 71.2 bits (173), Expect = 1e-11 Identities = 215/940 (22%), Positives = 328/940 (34%), Gaps = 150/940 (15%) Query: 1266 VLETAAPGVEDISGLPSG--EVLETTAPGVEEISGLPS--GEVLETTAPGVDEISGLPSG 1321 V+ETA P E + PS L T+ + + S G ET+ G + S P Sbjct: 110 VMETAPPD-EMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTE--SSTPVT 166 Query: 1322 EVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVED-ISGLPSGE 1380 + TA G E S S TSA S E S + + PS Sbjct: 167 SAVSITA-GQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFS 225 Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGF-----GDLSGLP 1435 + +G PSGE +S V + S + S E++ +++G G+ S +P Sbjct: 226 PSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTS-EKITVTTSTGSTLGNPGETSSVP 284 Query: 1436 SGGEGLE-TSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGK 1494 G + TSA+ V D P G+ S + +D + + + + Sbjct: 285 VTGSLMPVTSAALVTFD----PEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINT 340 Query: 1495 LPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVE 1554 L TL PSGF+ SG PSG S PS LV S + Sbjct: 341 L--NTLTPVTTSTVLSSPSGFNP--SGTVSQETFPSGETTTSS-PSSVSNTFLVTSKVFR 395 Query: 1555 VVTASTASELEGRGTIGISGAGEISGLPSS--------ELDISGRASGLP---------- 1596 + T S S L +S +G IS + S L + S LP Sbjct: 396 MPT-SRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQ 454 Query: 1597 --SGTELSGQ----ASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPG 1650 G E +G+ +S SP VS EI L + PS F T TEL S+G Sbjct: 455 QSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAAT 514 Query: 1651 --ISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706 ++G S GT P ++ + GE S + LP +GA + T Sbjct: 515 RLVTGNPSTGTAGTIPRVPSKVSAI-GEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGT 573 Query: 1707 SGSGESSGITFVDTSLVEVA--PTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQF 1764 +G S ++ T +++ A P++ + S +++ PS + S Q Sbjct: 574 TGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHST---STSPQE 630 Query: 1765 SGTVDSSGFTS--QTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSG-TPSSFPTVS 1821 S V G T QT + S ++ ++ + GSS + + S P PT+S Sbjct: 631 SPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTIS 690 Query: 1822 L-------------VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFL 1868 + ++ AP++ +A GPSG LS +G L Sbjct: 691 AATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLS------------KTGAL 738 Query: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFV 1928 L+ + ++ G P G TS AS P+ + Sbjct: 739 TLA---NSVVSTPGGPEG---------------------QWTSASASTSPDTAAAMTH-- 772 Query: 1929 EGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSE 1988 TH + E+SG+ T+ S + ++ P SS Sbjct: 773 ------------------THQAESTEASGQTQTSEPASSGSRTTSAG----TATPSSSGA 810 Query: 1989 TSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEAS 2048 + P G S + E +R S S TT + E +S + ST G AS Sbjct: 811 SGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVST-----GMAS 865 Query: 2049 AA------PEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTS 2102 + P +S ST G +P PSA+P + + ++ TS+ IS + Sbjct: 866 SIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLA 925 Query: 2103 IPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATS 2142 S+ T T I S+ L ETHT+ + S Sbjct: 926 ---SQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGS 962 Score = 66.6 bits (161), Expect = 3e-10 Identities = 184/749 (24%), Positives = 274/749 (36%), Gaps = 99/749 (13%) Query: 758 LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVEL 817 LP + A+T ++T P +++ + +P V PS S P P S Sbjct: 3537 LPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPL----PVTSTSS 3592 Query: 818 FPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVS 877 + P SPS SAS TP P + + D S TG Sbjct: 3593 VSTGHVTPLHVTSPS---SASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPL 3649 Query: 878 GHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGEL 937 D S +GD P D+S ++ + LPV S + ST L Sbjct: 3650 PVTDASSASTGDTT---PLPVTDTSSASTGQATPLPVTS---------LSSVSTGDTTPL 3697 Query: 938 PSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLP--SGEVLETTAPGVEDISGL 995 P + + S++ G + LP V S+ GD LP S T ++GL Sbjct: 3698 P----VTDASSASTGHATPLP---VTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGL 3750 Query: 996 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1055 S +TT V D S S T V D S S +TT V D+S +G Sbjct: 3751 SSASTGDTTPLPVTDTS---SASTRHATPLPVTDTS---SASTDDTTRLPVTDVSSASTG 3804 Query: 1056 EVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1115 T P ++ S +TT V D S + +G T+ P V S +G Sbjct: 3805 HA--TPLP----VTSTSSASTGDTTPLPVTDTSSVSTGHA--TSLP-VTSRSSASTGHA- 3854 Query: 1116 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV--LETAAPGVEDISGLPSGEVLE 1173 T P V D S + +G T P V S + +G L +P V Sbjct: 3855 -TPLP-VTDTSSVSTGHA--TPLP-VTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS 3909 Query: 1174 TAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231 T++ D + LP + L T ++ S +T+ V D S +G T Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHA--T 3967 Query: 1232 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAP 1291 P ++ L S +T V D S +G+ T P V +S + +G +TT Sbjct: 3968 PLP----LTSLSSVSTGDTTPLPVTDTSSASTGQA--TPLP-VTSLSSVSTG---DTTPL 4017 Query: 1292 GVEEISGLPSGEVLETTAPGVDEISGLPSGE-----VLETTAPGVEEISGLPSGEVLETS 1346 V S SG TT+ V + S + +G V T++ + + LP V +TS Sbjct: 4018 PVTIPSSASSG---HTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLP---VTDTS 4071 Query: 1347 TSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSAS 1406 +++ G + LP V + S + + LP TS S + P TSAS Sbjct: 4072 SASTGHATPLP----VTDTSSASTGHATPLP-----VTSLSSVSTGHATPLAVSSATSAS 4122 Query: 1407 GVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETS--ASEVGTDLSGLPSGREGLET 1464 V S + L++ G S GG TS + T +S +PS + T Sbjct: 4123 TV-------SSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS--TAMHT 4173 Query: 1465 SASGAEDLSGLPSGKEDL--VGSASGDLD 1491 ++ A + LP L G+ +GDL+ Sbjct: 4174 RSTAA-PIPILPERGVSLFPYGAGAGDLE 4201 Score = 61.2 bits (147), Expect = 1e-08 Identities = 209/996 (20%), Positives = 346/996 (34%), Gaps = 150/996 (15%) Query: 1252 APGVEDISGL------PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVL 1305 +P V +++G PSGE ++ V + S + S ++ TT+ G Sbjct: 225 SPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTG------------- 271 Query: 1306 ETTAPGVDEISGLP-SGEVLETTAPGVEEISGLPSGEVLET-STSAVGDLSGLPSGGEVL 1363 +T E S +P +G ++ T+ + ++ P G+ T S ++ D + + Sbjct: 272 -STLGNPGETSSVPVTGSLMPVTSAAL--VTFDPEGQSPATFSRTSTQDTTAFSKNHQTQ 328 Query: 1364 EISVSGVEDISGLPSGEVVETSA----------SGIEDVSELPSGEGLETSASGVED--- 1410 + + V I+ L + V TS SG PSGE +S S V + Sbjct: 329 SVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL 388 Query: 1411 ----LSRLPSGEE-----VLEISASGFGDLSGLPSGGEGL--ETSASEVGTDLSGLPSGR 1459 + R+P+ + E S S G +S + S + + S + S P Sbjct: 389 VTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKIS 448 Query: 1460 EGLETSASGAEDLSGLPSGKEDLVGSASGDL----DLGKLPSGTLGSGQAP-ETSGLPSG 1514 T S + +G P + S ++ + PS G + LPS Sbjct: 449 TAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPST 508 Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPS--------GFPTVSLVDSTLVEVVTASTASELEG 1566 +G + + G+ +PS G PT ST + T + A + + Sbjct: 509 STGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGA-QTQW 567 Query: 1567 RGTIGISGAGEISGLPSSELDISGRASGLPSGTEL-----SGQASGSPDVSGEIPGLFGV 1621 G +G +S PS + + + PS + + S Q + +P + Sbjct: 568 TQETGTTGEALLSS-PSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTST 626 Query: 1622 SGQPS---------GFPDTSGETSGVTELSGLSSGQ----PGISGEASGVLYGTSQPFGI 1668 S Q S P T+ E+ +S ++ + PG S ASG P Sbjct: 627 SPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDA 686 Query: 1669 TDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT 1728 +S T+ P +G + A P T G S G + T + +A + Sbjct: 687 PTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATL---GPSGGTSLSKTGALTLANS 743 Query: 1729 TFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIA 1788 V G P G+ + S D + + T +++ E SG Sbjct: 744 V---------VSTPGGPEGQWTSASASTSPDTAAAMTHT-----HQAESTEASGQTQTSE 789 Query: 1789 EVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGIL 1848 S S G++ PS + TPS +S T S + + + + +L Sbjct: 790 PASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTT-QSTTELL 848 Query: 1849 ELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPS--GEPPGTPYFSGDFASTTNVSGESSV 1906 S +H P +G S + L E S G P G + AS + S + Sbjct: 849 SASASHGAIPVSTGMASSIVP-GTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRM 907 Query: 1907 AM----GTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVST 1961 A TS + + + T F P G P T T L S SGK T Sbjct: 908 AQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFT 967 Query: 1962 AGDISGATPVLPGSGVEVSS--------VPESSSETSAY--------PEAGFGASAAP-- 2003 IS ATP LP + +S V ++SS ++ + P + P Sbjct: 968 TALISNATP-LPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLP 1026 Query: 2004 --EASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTS 2061 + S E +G TS F A+ S+ L V+ T + G + P S S +T Sbjct: 1027 VTDTSSESTGHVTPLPVTS-FSSASTGDSTPLPVT-DTSSASTGHVTPLPVTSLSSASTG 1084 Query: 2062 D------VGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRP 2115 D T + AT D + +S +GHT+ L V ++S Sbjct: 1085 DTTPLPVTDTSSASTGHATSLPVTDTSSVS---TGHTTPLPVTDTSSASTGH-------- 1133 Query: 2116 AETHLEIESSSLLYSGEET--HTVETATSPTDASIP 2149 T L + +S + +G T H + +++ T + P Sbjct: 1134 -ATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATP 1168 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 127 bits (320), Expect = 1e-28 Identities = 298/1114 (26%), Positives = 375/1114 (33%), Gaps = 205/1114 (18%) Query: 755 PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814 PG++ P TG E +P E P P P +V P Sbjct: 342 PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397 Query: 815 VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865 FP E E P P P P PP P+ +P S E E G P Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457 Query: 866 VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917 G G + G G G SG P G GL GS G P + G Sbjct: 458 PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 918 LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975 G P + P GA GS GD+ P G+ E + G L G Sbjct: 516 -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573 Query: 976 LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020 LP G + PG+ G P G E PG + GLP G V Sbjct: 574 LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072 E GV G P G+ +T T PG + G P G+V PG+ GLP Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128 G E PG+ GLP G PG+ G P G + PG G Sbjct: 693 GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746 Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175 P GE A PG GLP G PG + GLP G+V Sbjct: 747 PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228 PG GLP V P G + G+P GE + PG+ D+ G P Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860 Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286 E +PG+ G P G PG SG P GE+ PG G+P Sbjct: 861 -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914 Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331 + PG++ GL P+GE PG+ G GE E PG+ Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974 Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385 +SG + L G LSG P G + G + G P G + + Sbjct: 975 PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033 Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438 G + V P G+ + + G+ + I G G P G Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488 G++ S + G L GLP G+ GL G + +SG P G L G G Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149 Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538 + G P G G P G+P +G GE G+ P GLP S GL Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209 Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG-RGTIGISGAGEISG 1580 P GFP V S LEG +G G G G Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 1581 LPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----GFPDTSG 1633 LP E GLP + G+ G P + G +PGL G G P G P +G Sbjct: 1265 LPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPGLNG 1318 Query: 1634 ETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET------SGVP 1679 GV G+ SG PG +G E L G P G+ SG++ +G P Sbjct: 1319 MKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPP 1378 Query: 1680 DLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711 + GQP GLPG G P + G T G+ Sbjct: 1379 GIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1407 Score = 119 bits (299), Expect = 3e-26 Identities = 312/1223 (25%), Positives = 409/1223 (33%), Gaps = 217/1223 (17%) Query: 748 PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP 807 P G PG LP +P T P +P P P +P + E FP Sbjct: 88 PKGIRGPPG-LPGFPGT----------PGLPGMPGHDGAPGPQGIP--GCNGTKGERGFP 134 Query: 808 SVRPFPSVELFPSEEPFPSKEPSP-----SEEPSASEEPYTPSPP----VPSWTELPSSG 858 FP ++ P P + P S P P P PP +P T +P Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918 G P + G GLP G + GL G E GL Sbjct: 195 GPPGPPGLMGP-------------------PGPPGLP-GPKGNMGLNFQGPKGEKGEQGL 234 Query: 919 --PSGDEERIEWPSTPTVGELPSGAEILEGSAS-----GVGDLSGLPSGEVLETSASGVG 971 P G +I P E G + L G G+ G P GE E G Sbjct: 235 QGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEP 294 Query: 972 DLSGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVED 1029 G P G+ E PG+ + G P GE G + +G P L PG Sbjct: 295 GKRGKP-GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG--- 350 Query: 1030 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1089 +G+ GE G + GLP GE E PG++ GLP P G Sbjct: 351 -TGITIGE------KGNIGLPGLP-GEKGERGFPGIQGPPGLPGPPGAAVMGP--PGPPG 400 Query: 1090 LPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL------PSGEVLETAAPGV 1141 P G+ + PG+ I G P G + APG+ G PS E+ E PG Sbjct: 401 FPGERGQKGDEGPPGIS-IPG-PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG- 457 Query: 1142 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1201 P G + G + + G G ISG P G+ PG Sbjct: 458 ------PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG---ISG-PPGQPGLPGLPGPPGS 507 Query: 1202 SGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS 1259 G P GE + A G + + G+P APG G P G++L PG++ Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAP----GAPGFPGSKGEP-GDIL--TFPGMKG-- 558 Query: 1260 GLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVL--ETTAPGVDEISG 1317 GE+ APG+ + G P + L PG+ G P G E PG + G Sbjct: 559 --DKGELGSPGAPGLPGLPGTPGQDGL----PGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLP 1377 LP G + PG P G V E V G P G+ G P Sbjct: 613 LP-GNIGPMGPPGFG-----PPGPVGEKGIQGVAGNPGQP-----------GIPGPKGDP 655 Query: 1378 SGEVVETSASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLP 1435 + + G+ GL + G L +P + I G G P Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG-P 714 Query: 1436 SGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKL 1495 G G+ GT GR GLE G G P K + + G L Sbjct: 715 KGFPGIPGPPGAPGTP------GRIGLE----GPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 1496 PS--GTLGSGQAPETSGLPSGFSGEYSGVDLGSGP-----PSGLPDFSGLPSGFPTVSLV 1548 P G LG G P G G +G+D GP P+G P G P G P + + Sbjct: 765 PGFKGALGPKGDRGFPG-PPGPPGR-TGLDGLPGPKGDVGPNGQPGPMG-PPGLPGIGVQ 821 Query: 1549 DSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQAS-- 1606 + G IG G + G+P + D P G ++ G Sbjct: 822 GPPGPPGIP----------GPIGQPG---LHGIPGEKGDPG------PPGLDVPGPPGER 862 Query: 1607 GSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPF 1666 GSP + G PG G G P G P +G +SG PG GE + G P Sbjct: 863 GSPGIPGA-PGPIGPPGSP-GLPGKAG-----------ASGFPGTKGEMG--MMGPPGPP 907 Query: 1667 GITDLSGETSGVPDLSGQPS--GLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVE 1724 G + G SGVP L G G PG G T G+ G +D +L+ Sbjct: 908 GPLGIPGR-SGVPGLKGDDGLQGQPGLPGPTGE-----KGSKGEPGLPGPPGPMDPNLL- 960 Query: 1725 VAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLP 1784 K E GL + P G L G G +SGQ G G P G P Sbjct: 961 -GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ-PGLPGPPG-PKGNPGLPGQP 1017 Query: 1785 SGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGP 1844 I + + ++G P G G PS P + + Q+ +G Sbjct: 1018 GLIGPPGLKGTIGDMGFPGPQGV-EGPPGPSGVPG---------QPGSPGLPGQKGDKGD 1067 Query: 1845 SGILELSGAHSGAPDMSGEHS--GFLDLSGLQSGLIEPSGEP--PGTPYFSGD-----FA 1895 GI + G P GE G+ G++ + +P G P PGTP G F Sbjct: 1068 PGISSI--GLPGLPGPKGEPGLPGYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLPGFP 1124 Query: 1896 STTNVSGESSVAMGTSGEASGLP 1918 T G ++ G G GLP Sbjct: 1125 GTPGPPGPKGIS-GPPGN-PGLP 1145 Score = 95.1 bits (235), Expect = 7e-19 Identities = 188/687 (27%), Positives = 241/687 (35%), Gaps = 138/687 (20%) Query: 748 PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798 P+G LPGI PP P +P +P P +VP P E Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 799 --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828 P P P FP + P P L P P + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 829 -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883 P P+ E + EP P PP P L S E G P + G VSG + Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984 Query: 884 GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937 G L GD SG G G+ GLP + GL P G T+G++ Sbjct: 985 G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035 Query: 938 -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991 P G E G SGV G P G+ + S +G L GLP G E PG Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092 Query: 992 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051 G+ G V + PG+ + G P + PG+ G P PG + ISG Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137 Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107 P L PG G P G E PG + I G P+G+ E PG + Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195 Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1163 GLP SG+ + PG+ GL P GE PGV+ G P + P +E Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG-----SPGPALEGP 1250 Query: 1164 SGL--PSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1219 G P G PG E GLP G E PG + GLP G + PG++ Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGLQG 1309 Query: 1220 ISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSGEV 1266 G P +G + PGV G+ P GE PG + G PSG+ Sbjct: 1310 NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSGQS 1368 Query: 1267 L----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEISG 1317 + + PG+ GL PG + GLP G+ PG D G Sbjct: 1369 IIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421 Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLE 1344 G+ PG + G P + L+ Sbjct: 1422 -RKGDPGLPGQPGTRGLDGPPGPDGLQ 1447 Score = 33.5 bits (75), Expect = 2.6 Identities = 64/266 (24%), Positives = 75/266 (28%), Gaps = 40/266 (15%) Query: 645 GDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQ 704 G PG+ P GLP P F G+ P P G P G Q Sbjct: 1207 GGLPGI------PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG---PQ 1257 Query: 705 VVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPT 764 PG +P E +P + E +P G LPG+ P Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNG-------GIKGEKGNPGQP-----GLPGLPGLKGDQGPP 1305 Query: 765 GAATEESTEG-------PSATEVPSASEEPSPSEVP---FPSEEPSPSEEPFPSVRPFPS 814 G G P VP PS VP P EP P P P PS Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365 Query: 815 VELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSG--DFTG 872 + + P P P P P LP G P +G F G Sbjct: 1366 -----GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ--GLPGPTGPPGDPGRNGLPGFDG 1418 Query: 873 SGDVSGHLDFSGQLSGDRASGLPSGD 898 +G G GQ G P D Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDGPPGPD 1444 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 125 bits (315), Expect = 4e-28 Identities = 298/1120 (26%), Positives = 375/1120 (33%), Gaps = 211/1120 (18%) Query: 755 PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814 PG++ P TG E +P E P P P +V P Sbjct: 342 PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397 Query: 815 VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865 FP E E P P P P PP P+ +P S E E G P Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457 Query: 866 VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917 G G + G G G SG P G GL GS G P + G Sbjct: 458 PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 918 LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975 G P + P GA GS GD+ P G+ E + G L G Sbjct: 516 -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573 Query: 976 LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020 LP G + PG+ G P G E PG + GLP G V Sbjct: 574 LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072 E GV G P G+ +T T PG + G P G+V PG+ GLP Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128 G E PG+ GLP G PG+ G P G + PG G Sbjct: 693 GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746 Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175 P GE A PG GLP G PG + GLP G+V Sbjct: 747 PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228 PG GLP V P G + G+P GE + PG+ D+ G P Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860 Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286 E +PG+ G P G PG SG P GE+ PG G+P Sbjct: 861 -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914 Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331 + PG++ GL P+GE PG+ G GE E PG+ Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974 Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385 +SG + L G LSG P G + G + G P G + + Sbjct: 975 PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033 Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438 G + V P G+ + + G+ + I G G P G Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488 G++ S + G L GLP G+ GL G + +SG P G L G G Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149 Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538 + G P G G P G+P +G GE G+ P GLP S GL Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209 Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG-------RGTIGISG 1574 P GFP V S LEG +G G G Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----G 1627 GLP E GLP + G+ G P + G +PGL G G P G Sbjct: 1265 PTGFQGLPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPG 1318 Query: 1628 FPDTSGETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET---- 1675 P +G GV G+ SG PG +G E L G P G+ SG++ Sbjct: 1319 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1378 Query: 1676 --SGVPDLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711 +G P + GQP GLPG G P + G T G+ Sbjct: 1379 GDAGPPGIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1413 Score = 95.5 bits (236), Expect = 6e-19 Identities = 191/689 (27%), Positives = 243/689 (35%), Gaps = 136/689 (19%) Query: 748 PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798 P+G LPGI PP P +P +P P +VP P E Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 799 --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828 P P P FP + P P L P P + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 829 -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883 P P+ E + EP P PP P L S E G P + G VSG + Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984 Query: 884 GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937 G L GD SG G G+ GLP + GL P G T+G++ Sbjct: 985 G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035 Query: 938 -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991 P G E G SGV G P G+ + S +G L GLP G E PG Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092 Query: 992 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051 G+ G V + PG+ + G P + PG+ G P PG + ISG Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137 Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107 P L PG G P G E PG + I G P+G+ E PG + Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195 Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPS--GEVLE--TAAPG 1159 GLP SG+ + PG+ GL P GE PGV+ G P G LE PG Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 1160 VEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217 + G P G PG E GLP G E PG + GLP G + PG+ Sbjct: 1256 PQGPPGRP-GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGL 1313 Query: 1218 EDISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSG 1264 + G P +G + PGV G+ P GE PG + G PSG Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSG 1372 Query: 1265 EVL----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEI 1315 + + + PG+ GL PG + GLP G+ PG D Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1425 Query: 1316 SGLPSGEVLETTAPGVEEISGLPSGEVLE 1344 G G+ PG + G P + L+ Sbjct: 1426 GG-RKGDPGLPGQPGTRGLDGPPGPDGLQ 1453 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 125 bits (315), Expect = 4e-28 Identities = 298/1117 (26%), Positives = 374/1117 (33%), Gaps = 208/1117 (18%) Query: 755 PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814 PG++ P TG E +P E P P P +V P Sbjct: 342 PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397 Query: 815 VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865 FP E E P P P P PP P+ +P S E E G P Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457 Query: 866 VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917 G G + G G G SG P G GL GS G P + G Sbjct: 458 PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515 Query: 918 LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975 G P + P GA GS GD+ P G+ E + G L G Sbjct: 516 -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573 Query: 976 LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020 LP G + PG+ G P G E PG + GLP G V Sbjct: 574 LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632 Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072 E GV G P G+ +T T PG + G P G+V PG+ GLP Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692 Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128 G E PG+ GLP G PG+ G P G + PG G Sbjct: 693 GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746 Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175 P GE A PG GLP G PG + GLP G+V Sbjct: 747 PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805 Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228 PG GLP V P G + G+P GE + PG+ D+ G P Sbjct: 806 QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860 Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286 E +PG+ G P G PG SG P GE+ PG G+P Sbjct: 861 -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914 Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331 + PG++ GL P+GE PG+ G GE E PG+ Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974 Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385 +SG + L G LSG P G + G + G P G + + Sbjct: 975 PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033 Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438 G + V P G+ + + G+ + I G G P G Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488 G++ S + G L GLP G+ GL G + +SG P G L G G Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149 Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538 + G P G G P G+P +G GE G+ P GLP S GL Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209 Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG----RGTIGISGAGE 1577 P GFP V S LEG G G G Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264 Query: 1578 ISGLPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----GFPD 1630 GLP E GLP + G+ G P + G +PGL G G P G P Sbjct: 1265 FQGLPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPG 1318 Query: 1631 TSGETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET------S 1676 +G GV G+ SG PG +G E L G P G+ SG++ + Sbjct: 1319 LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1378 Query: 1677 GVPDLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711 G P + GQP GLPG G P + G T G+ Sbjct: 1379 GPPGIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1410 Score = 95.9 bits (237), Expect = 4e-19 Identities = 191/689 (27%), Positives = 244/689 (35%), Gaps = 139/689 (20%) Query: 748 PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798 P+G LPGI PP P +P +P P +VP P E Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 799 --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828 P P P FP + P P L P P + Sbjct: 869 GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928 Query: 829 -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883 P P+ E + EP P PP P L S E G P + G VSG + Sbjct: 929 GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984 Query: 884 GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937 G L GD SG G G+ GLP + GL P G T+G++ Sbjct: 985 G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035 Query: 938 -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991 P G E G SGV G P G+ + S +G L GLP G E PG Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092 Query: 992 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051 G+ G V + PG+ + G P + PG+ G P PG + ISG Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137 Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107 P L PG G P G E PG + I G P+G+ E PG + Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195 Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPS--GEVLE--TAAPG 1159 GLP SG+ + PG+ GL P GE PGV+ G P G LE PG Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 1160 VEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217 + G P + L PG E GLP G E PG + GLP G + PG+ Sbjct: 1256 PQGPPGRPGFQGL----PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGL 1310 Query: 1218 EDISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSG 1264 + G P +G + PGV G+ P GE PG + G PSG Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSG 1369 Query: 1265 EVL----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEI 1315 + + + PG+ GL PG + GLP G+ PG D Sbjct: 1370 QSIIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1422 Query: 1316 SGLPSGEVLETTAPGVEEISGLPSGEVLE 1344 G G+ PG + G P + L+ Sbjct: 1423 GG-RKGDPGLPGQPGTRGLDGPPGPDGLQ 1450 Score = 33.1 bits (74), Expect = 3.4 Identities = 63/266 (23%), Positives = 74/266 (27%), Gaps = 37/266 (13%) Query: 645 GDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQ 704 G PG+ P GLP P F G+ P P G P G Sbjct: 1207 GGLPGI------PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1260 Query: 705 VVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPT 764 PG +P E +P + E +P G LPG+ P Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNG-------GIKGEKGNPGQP-----GLPGLPGLKGDQGPP 1308 Query: 765 GAATEESTEG-------PSATEVPSASEEPSPSEVP---FPSEEPSPSEEPFPSVRPFPS 814 G G P VP PS VP P EP P P P PS Sbjct: 1309 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1368 Query: 815 VELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSG--DFTG 872 + + P P P P P LP G P +G F G Sbjct: 1369 -----GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ--GLPGPTGPPGDPGRNGLPGFDG 1421 Query: 873 SGDVSGHLDFSGQLSGDRASGLPSGD 898 +G G GQ G P D Sbjct: 1422 AGGRKGDPGLPGQPGTRGLDGPPGPD 1447 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 124 bits (311), Expect = 1e-27 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%) Query: 844 PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892 P PP PS S G E GAP G F GS V G+ F G + D Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 893 GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952 G GD+ G G ++ GD E P P P G G G Sbjct: 330 G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384 Query: 953 D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002 L G P L+ S G D G P G PG G P V Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060 PG + G +PG+ + G P GE +L T P + GLP Sbjct: 445 KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490 Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097 PG+ + G+P G +PG +GLP GE L + Sbjct: 491 -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549 Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157 PG + G P + L+ PG + GLP G E A G + G P G+ + Sbjct: 550 VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606 Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207 PG +G P G E G + + G P GE+ + T PG P G Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659 Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258 PG + G+P G+ + PG + G+P G + PG + Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312 G P + PG+ GLP + A PG G P SGE E PG+ Sbjct: 720 LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775 Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365 + G P E L + PG G P G +E A G L+GL G+ Sbjct: 776 PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832 Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419 +G + G+P SG ET + GI E+ P G+ G+ P GE+ Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888 Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476 + I GF G P G G + + G+ G+P G+ G A G + G P Sbjct: 889 GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943 Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526 G+ L G A + G G G GLP DLGS Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586 G P G+P + + S RGT+G G GLP Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047 Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643 + G G P +E G G P +G+ +PG G G+ G P G E + Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103 Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698 S G PG+ G+ G G + G G P + G P GLPGF G+ + Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156 Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756 D + G GE T L+ P G+ G P G L G+ G Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207 Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815 + +G G GF P GLP I + G++ +R GS GA G P Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260 Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874 S D+ ++ + P GP G L G G P G+ GF G++ Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318 Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913 G I P G P G P GD + +S S GT GE Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Score = 63.5 bits (153), Expect = 2e-09 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%) Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300 LP VL AAP + G+ A G + G P +PG + +G P Sbjct: 14 LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68 Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360 G PG G P L T + GV ISGLP S L G P Sbjct: 69 EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113 Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418 +G + G+P SG E G+ P G A+G++ P+ E Sbjct: 114 -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162 Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462 E +E+ A G L G P G +GL G P G G Sbjct: 163 EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221 Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514 G + L+G P ++ + +G DL K G +G P SGLP Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574 G G G G P G+P GFP V +G G G Sbjct: 282 SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321 Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632 G+ + DI P+ + Q G G PG G G PSG P Sbjct: 322 LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380 Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692 G + G PG+ G G T G P +G P GLPG Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432 Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 G D+V G G S GI VD K E GL + +P Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800 G L G G+ V G G ++G +P +GLP G G+ + E G Sbjct: 484 -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857 +L P G G P R ++ + P + GP G L LSG G Sbjct: 542 ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597 Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917 P G S G P+G P P T V G A G GEA Sbjct: 598 PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976 P L S V G P PP PQ G + GD P LPG Sbjct: 644 PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691 Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035 E P GF P+ + G+ E L GL G Sbjct: 692 GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740 Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080 G G P GE + + G PGLP T + Sbjct: 741 KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 124 bits (311), Expect = 1e-27 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%) Query: 844 PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892 P PP PS S G E GAP G F GS V G+ F G + D Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 893 GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952 G GD+ G G ++ GD E P P P G G G Sbjct: 330 G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384 Query: 953 D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002 L G P L+ S G D G P G PG G P V Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060 PG + G +PG+ + G P GE +L T P + GLP Sbjct: 445 KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490 Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097 PG+ + G+P G +PG +GLP GE L + Sbjct: 491 -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549 Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157 PG + G P + L+ PG + GLP G E A G + G P G+ + Sbjct: 550 VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606 Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207 PG +G P G E G + + G P GE+ + T PG P G Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659 Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258 PG + G+P G+ + PG + G+P G + PG + Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312 G P + PG+ GLP + A PG G P SGE E PG+ Sbjct: 720 LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775 Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365 + G P E L + PG G P G +E A G L+GL G+ Sbjct: 776 PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832 Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419 +G + G+P SG ET + GI E+ P G+ G+ P GE+ Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888 Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476 + I GF G P G G + + G+ G+P G+ G A G + G P Sbjct: 889 GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943 Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526 G+ L G A + G G G GLP DLGS Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586 G P G+P + + S RGT+G G GLP Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047 Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643 + G G P +E G G P +G+ +PG G G+ G P G E + Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103 Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698 S G PG+ G+ G G + G G P + G P GLPGF G+ + Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156 Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756 D + G GE T L+ P G+ G P G L G+ G Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207 Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815 + +G G GF P GLP I + G++ +R GS GA G P Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260 Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874 S D+ ++ + P GP G L G G P G+ GF G++ Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318 Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913 G I P G P G P GD + +S S GT GE Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Score = 63.5 bits (153), Expect = 2e-09 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%) Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300 LP VL AAP + G+ A G + G P +PG + +G P Sbjct: 14 LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68 Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360 G PG G P L T + GV ISGLP S L G P Sbjct: 69 EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113 Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418 +G + G+P SG E G+ P G A+G++ P+ E Sbjct: 114 -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162 Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462 E +E+ A G L G P G +GL G P G G Sbjct: 163 EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221 Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514 G + L+G P ++ + +G DL K G +G P SGLP Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574 G G G G P G+P GFP V +G G G Sbjct: 282 SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321 Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632 G+ + DI P+ + Q G G PG G G PSG P Sbjct: 322 LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380 Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692 G + G PG+ G G T G P +G P GLPG Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432 Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 G D+V G G S GI VD K E GL + +P Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800 G L G G+ V G G ++G +P +GLP G G+ + E G Sbjct: 484 -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857 +L P G G P R ++ + P + GP G L LSG G Sbjct: 542 ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597 Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917 P G S G P+G P P T V G A G GEA Sbjct: 598 PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976 P L S V G P PP PQ G + GD P LPG Sbjct: 644 PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691 Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035 E P GF P+ + G+ E L GL G Sbjct: 692 GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740 Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080 G G P GE + + G PGLP T + Sbjct: 741 KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 124 bits (311), Expect = 1e-27 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%) Query: 844 PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892 P PP PS S G E GAP G F GS V G+ F G + D Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 893 GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952 G GD+ G G ++ GD E P P P G G G Sbjct: 330 G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384 Query: 953 D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002 L G P L+ S G D G P G PG G P V Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060 PG + G +PG+ + G P GE +L T P + GLP Sbjct: 445 KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490 Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097 PG+ + G+P G +PG +GLP GE L + Sbjct: 491 -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549 Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157 PG + G P + L+ PG + GLP G E A G + G P G+ + Sbjct: 550 VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606 Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207 PG +G P G E G + + G P GE+ + T PG P G Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659 Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258 PG + G+P G+ + PG + G+P G + PG + Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312 G P + PG+ GLP + A PG G P SGE E PG+ Sbjct: 720 LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775 Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365 + G P E L + PG G P G +E A G L+GL G+ Sbjct: 776 PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832 Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419 +G + G+P SG ET + GI E+ P G+ G+ P GE+ Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888 Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476 + I GF G P G G + + G+ G+P G+ G A G + G P Sbjct: 889 GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943 Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526 G+ L G A + G G G GLP DLGS Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586 G P G+P + + S RGT+G G GLP Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047 Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643 + G G P +E G G P +G+ +PG G G+ G P G E + Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103 Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698 S G PG+ G+ G G + G G P + G P GLPGF G+ + Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156 Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756 D + G GE T L+ P G+ G P G L G+ G Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207 Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815 + +G G GF P GLP I + G++ +R GS GA G P Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260 Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874 S D+ ++ + P GP G L G G P G+ GF G++ Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318 Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913 G I P G P G P GD + +S S GT GE Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Score = 63.5 bits (153), Expect = 2e-09 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%) Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300 LP VL AAP + G+ A G + G P +PG + +G P Sbjct: 14 LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68 Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360 G PG G P L T + GV ISGLP S L G P Sbjct: 69 EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113 Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418 +G + G+P SG E G+ P G A+G++ P+ E Sbjct: 114 -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162 Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462 E +E+ A G L G P G +GL G P G G Sbjct: 163 EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221 Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514 G + L+G P ++ + +G DL K G +G P SGLP Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574 G G G G P G+P GFP V +G G G Sbjct: 282 SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321 Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632 G+ + DI P+ + Q G G PG G G PSG P Sbjct: 322 LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380 Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692 G + G PG+ G G T G P +G P GLPG Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432 Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 G D+V G G S GI VD K E GL + +P Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800 G L G G+ V G G ++G +P +GLP G G+ + E G Sbjct: 484 -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857 +L P G G P R ++ + P + GP G L LSG G Sbjct: 542 ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597 Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917 P G S G P+G P P T V G A G GEA Sbjct: 598 PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976 P L S V G P PP PQ G + GD P LPG Sbjct: 644 PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691 Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035 E P GF P+ + G+ E L GL G Sbjct: 692 GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740 Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080 G G P GE + + G PGLP T + Sbjct: 741 KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 124 bits (311), Expect = 1e-27 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%) Query: 844 PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892 P PP PS S G E GAP G F GS V G+ F G + D Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 893 GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952 G GD+ G G ++ GD E P P P G G G Sbjct: 330 G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384 Query: 953 D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002 L G P L+ S G D G P G PG G P V Sbjct: 385 SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444 Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060 PG + G +PG+ + G P GE +L T P + GLP Sbjct: 445 KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490 Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097 PG+ + G+P G +PG +GLP GE L + Sbjct: 491 -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549 Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157 PG + G P + L+ PG + GLP G E A G + G P G+ + Sbjct: 550 VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606 Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207 PG +G P G E G + + G P GE+ + T PG P G Sbjct: 607 PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659 Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258 PG + G+P G+ + PG + G+P G + PG + Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719 Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312 G P + PG+ GLP + A PG G P SGE E PG+ Sbjct: 720 LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775 Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365 + G P E L + PG G P G +E A G L+GL G+ Sbjct: 776 PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832 Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419 +G + G+P SG ET + GI E+ P G+ G+ P GE+ Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888 Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476 + I GF G P G G + + G+ G+P G+ G A G + G P Sbjct: 889 GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943 Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526 G+ L G A + G G G GLP DLGS Sbjct: 944 PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586 G P G+P + + S RGT+G G GLP Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047 Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643 + G G P +E G G P +G+ +PG G G+ G P G E + Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103 Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698 S G PG+ G+ G G + G G P + G P GLPGF G+ + Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156 Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756 D + G GE T L+ P G+ G P G L G+ G Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207 Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815 + +G G GF P GLP I + G++ +R GS GA G P Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260 Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874 S D+ ++ + P GP G L G G P G+ GF G++ Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318 Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913 G I P G P G P GD + +S S GT GE Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Score = 63.5 bits (153), Expect = 2e-09 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%) Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300 LP VL AAP + G+ A G + G P +PG + +G P Sbjct: 14 LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68 Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360 G PG G P L T + GV ISGLP S L G P Sbjct: 69 EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113 Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418 +G + G+P SG E G+ P G A+G++ P+ E Sbjct: 114 -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162 Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462 E +E+ A G L G P G +GL G P G G Sbjct: 163 EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221 Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514 G + L+G P ++ + +G DL K G +G P SGLP Sbjct: 222 VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281 Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574 G G G G P G+P GFP V +G G G Sbjct: 282 SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321 Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632 G+ + DI P+ + Q G G PG G G PSG P Sbjct: 322 LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380 Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692 G + G PG+ G G T G P +G P GLPG Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432 Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 G D+V G G S GI VD K E GL + +P Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800 G L G G+ V G G ++G +P +GLP G G+ + E G Sbjct: 484 -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857 +L P G G P R ++ + P + GP G L LSG G Sbjct: 542 ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597 Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917 P G S G P+G P P T V G A G GEA Sbjct: 598 PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976 P L S V G P PP PQ G + GD P LPG Sbjct: 644 PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691 Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035 E P GF P+ + G+ E L GL G Sbjct: 692 GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740 Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080 G G P GE + + G PGLP T + Sbjct: 741 KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 121 bits (303), Expect = 9e-27 Identities = 334/1304 (25%), Positives = 441/1304 (33%), Gaps = 243/1304 (18%) Query: 718 TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSA 777 T+ V +G ILE + +P++ TE G L T A E EG + Sbjct: 308 TSTVTTGLNATILERSLDPDSGTEL-------------GTLET-----KAAREDEEGDDS 349 Query: 778 TEVPS--ASEEPSPSEV---PFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPS 832 T P A+E PS ++ P E+ + E P+V P P P PS Sbjct: 350 TMGPDFRAAEYPSRTQFQIFPGAGEKGAKGE---PAVIEKGQQFEGPPGAPGPQGVVGPS 406 Query: 833 EEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRAS 892 P P P PP P+ LP G P + G G V + Q +G Sbjct: 407 GPPGPPGFPGDPGPPGPA--GLP------GIPGIDGIRGPPGTV---IMMPFQFAGGSFK 455 Query: 893 GLP-------------------SGDLDSSGLTSTVGS-GLPVESGLPSGDEERIEWPSTP 932 G P G GLT G GLP GL EE E P P Sbjct: 456 GPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKG--EEGAEGPQGP 513 Query: 933 TVGELPSG--AEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPS--------GEVL 982 + P G + + G GLP G+ G L GLP G V Sbjct: 514 RGLQGPHGPPGRVGKMGRPGADGARGLP-GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVG 572 Query: 983 ETTAPGVEDISGL--PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP--SGEV 1038 + PG + G P G + PG + G P G T PGV I G P G V Sbjct: 573 QPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG-PRGSPGPTGRPGVTGIDGAPGAKGNV 631 Query: 1039 LETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLET 1098 PG G + L PG + + G P E PG I GLP G Sbjct: 632 GPPGEPGPPGQQGNHGSQGL----PGPQGLIGTPG----EKGPPGNPGIPGLP-GSDGPL 682 Query: 1099 AAPGVEDISGL-----PSGEVLETAAPGVEDISGL--------PSGEVLETAAPGVEDIS 1145 PG E +G P G PG + G GE E PG + Sbjct: 683 GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742 Query: 1146 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1205 GL G+ + APG G P G + G E P G E GV + G P Sbjct: 743 GL-KGDQGKPGAPGPRGEDG-PEGPKGQAGQAGEEG----PPGSAGEKGKLGVPGLPGYP 796 Query: 1206 SGEVLETAAPGVEDISGLP--------SGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1257 PG + G P G+ +T PG+E G P G E PG Sbjct: 797 -------GRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERG-PPGSRGERGQPGATG 848 Query: 1258 ISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISG 1317 G P G+V + APG+ GLP + PG G P G + PG G Sbjct: 849 QPG-PKGDVGQDGAPGIPGEKGLPGLQ----GPPGFPGPKG-PPGHQGKDGRPGHPGQRG 902 Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGL- 1376 G +T PG + G P G+ E G P G E + G+E G Sbjct: 903 -ELGFQGQTGPPGPAGVLG-PQGKTGEVGPLGERGPPGPP--GPPGEQGLPGLEGREGAK 958 Query: 1377 ----PSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLS 1432 P G + + +G+ G G + +G++ + P G S G L Sbjct: 959 GELGPPGPLGKEGPAGLRGFPGPKGGPG-DPGPTGLKG-DKGPPGPVGANGSPGERGPLG 1016 Query: 1433 GLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492 P+GG GL + G++ P+G++G + G G P+GK+ + G Sbjct: 1017 --PAGGIGL---PGQSGSEGPVGPAGKKG----SRGERGPPG-PTGKDGIPG-------- 1058 Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEYSGV----------DLGSGPPSGLPDFSGLPSGF 1542 P G LG P + PSG G+ V D G P G P G P+G Sbjct: 1059 ---PLGPLG----PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRG-PAGH 1110 Query: 1543 PTVSLVDSTLVEVVTASTASELEG---RGTIGISGAGEISGL---PSSELDISGRASGLP 1596 P D + RG +G+ G + GL P + ++ S P Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 1597 SGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEAS 1656 G + P S PGL G GQP G GE + G PGI G Sbjct: 1171 HGAP-GPRGPQGPTGSEGTPGLPGGVGQP-GAVGEKGERGDAGDPG--PPGAPGIPGPKG 1226 Query: 1657 GV-LYGTSQPFGITDLSGETSGVPDLSGQ-----PSGLPGFSGATSGVPDLVSGTTSGSG 1710 + G S P G G+ G P G P+GLPG G G P VSG G Sbjct: 1227 DIGEKGDSGPSGAAGPPGK-KGPPGEDGAKGSVGPTGLPGDLG-PPGDPG-VSGIDGSPG 1283 Query: 1711 ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ------- 1763 E V P E G PSG G+ G G+ Sbjct: 1284 EKGDPGDVGGP----GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPP 1339 Query: 1764 -FSGTVDSSGFTSQT-PE-FSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTV 1820 +G + + G + PE G+P + E + ++G P G PS P + Sbjct: 1340 GRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLG-------PSGLPGL 1392 Query: 1821 SLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEP 1880 + T + +G G++ L G P +GE G L G+Q G P Sbjct: 1393 ------------KGDTGPKGEKGHIGLIGL----IGPPGEAGE-KGDQGLPGVQ-GPPGP 1434 Query: 1881 SGEP-----------PGTPYFSGDFASTTNVSGESSVAMGTSGE 1913 G+P PG P +G + S MG G+ Sbjct: 1435 KGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGS--MGPRGD 1476 Score = 109 bits (272), Expect = 4e-23 Identities = 294/1156 (25%), Positives = 391/1156 (33%), Gaps = 198/1156 (17%) Query: 816 ELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPS---WTELPSSGEESGAPDVSGDFTG 872 E++ S P S E S + +E P PP P+ T ++G + + S D Sbjct: 269 EIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLD-PD 327 Query: 873 SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTP 932 SG G L+ D G ST+G D E+PS Sbjct: 328 SGTELGTLETKAARE------------DEEGDDSTMGP-----------DFRAAEYPSRT 364 Query: 933 TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDI 992 P G G+ + + G+ E G P G V + PG Sbjct: 365 QFQIFPGA-----GEKGAKGEPAVIEKGQQFEGPPGAPG-----PQGVVGPSGPPGPPGF 414 Query: 993 SGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP-------SGEVLETTA 1043 G P G PG++ I G P ++ G P + VL+ T Sbjct: 415 PGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQ 474 Query: 1044 PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL-----PSGEVLET 1098 ++ P G V T PG + G P G E A G + GL P G V + Sbjct: 475 LSMKG----PPGPVGLTGRPGPVGLPGHP-GLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529 Query: 1099 AAPGVEDISGLPSGEVLETAAPGVEDISGLPS--------GEVLETAAPGVEDISGL--P 1148 PG + GLP G+ G + + GLP G V + PG + G P Sbjct: 530 GRPGADGARGLP-GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP 588 Query: 1149 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPS 1206 G + PG + G P G T PGV I G P G V PG G Sbjct: 589 PGPTGQAGEPGPRGLLG-PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG 647 Query: 1207 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1266 + L PG + + G P E PG I GLP G PG E P+GE Sbjct: 648 SQGL----PGPQGLIGTPG----EKGPPGNPGIPGLP-GSDGPLGHPGHEG----PTGEK 694 Query: 1267 LETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLET 1326 PG G P ++ T+ G + G GE E PG GL G+ + Sbjct: 695 GAQGPPGSAGPPGYPGPRGVKGTS-GNRGLQG-EKGEKGEDGFPGFKGDVGL-KGDQGKP 751 Query: 1327 TAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLP--------- 1377 APG G P G + G+ S GE ++ V G+ G P Sbjct: 752 GAPGPRGEDG-PEGP--KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808 Query: 1378 --------SGEVVETSASGIEDVSELPS--GEGLETSASGVEDLSRLPSGEEVLEISASG 1427 G+ +T G+E P GE + A+G P G +V + A G Sbjct: 809 GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG----PKG-DVGQDGAPG 863 Query: 1428 FGDLSGLPS-----GGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDL 1482 GLP G G + G D G P G G + G + +G P G + Sbjct: 864 IPGEKGLPGLQGPPGFPGPKGPPGHQGKD--GRP-GHPG-QRGELGFQGQTG-PPGPAGV 918 Query: 1483 VGSASGDLDLGKL-PSGTLGSGQAPETSGLP-----SGFSGEYSGV-DLGSGPPSGLPDF 1535 +G ++G L G G P GLP G GE LG P+GL F Sbjct: 919 LGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978 Query: 1536 SGLPSGFP----TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591 G P G P L + S E RG +G +G + G SE + Sbjct: 979 PG-PKGGPGDPGPTGLKGDKGPPGPVGANGSPGE-RGPLGPAGGIGLPGQSGSEGPVG-- 1034 Query: 1592 ASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGVTELSGLS---- 1645 P+G + S G P +G+ IPG G G P G SGE ++ Sbjct: 1035 ----PAGKKGSRGERGPPGPTGKDGIPGPLGPLG-PPGAAGPSGEEGDKGDVGAPGHKGS 1089 Query: 1646 ---------SGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQ--PSGLPGFSGA 1694 GQPGI G A G P G G G P L GQ G+ GF G Sbjct: 1090 KGDKGDAGPPGQPGIRGPA-----GHPGPPGADGAQGR-RGPPGLFGQKGDDGVRGFVGV 1143 Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754 P + G GE + V + AP + GS GLP G G+ Sbjct: 1144 IG--PPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG----VGQ 1197 Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTP 1814 G V G+ D P G+P ++ + G++ P G G Sbjct: 1198 PGAVGEKGERGDAGDPG-----PPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGED 1252 Query: 1815 SSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874 + +V PT GP G +SG G+P G+ D+ G Sbjct: 1253 GAKGSV-------------GPTGLPGDLGPPGDPGVSGI-DGSPGEKGDPG---DVGG-- 1293 Query: 1875 SGLIEPSGEP--PGTP 1888 G SGEP PG P Sbjct: 1294 PGPPGASGEPGAPGPP 1309 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 119 bits (299), Expect = 3e-26 Identities = 363/1626 (22%), Positives = 549/1626 (33%), Gaps = 253/1626 (15%) Query: 692 TSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGT 751 T+ EE V+ PG TT PS T++ F EP+ + + T Sbjct: 137 TNSGHSEESTVSHSGPGATG------TTLFPSHSATSV--FVGEPKTSPITSAS---MET 185 Query: 752 SPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRP 811 + LPG T +E+ST S+ P + P+ + SE+ + S RP Sbjct: 186 TALPGSTTT----AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHS-----RP 236 Query: 812 FPSVEL-FPSEEPFP--SKEPSPSEE-PSASEEPYTPSPPVPSWTELPSSGEESGAPDVS 867 P+ + FP P S+E + S P +++ +P PS S G ES S Sbjct: 237 GPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPS-----SLGPESTTFHSS 291 Query: 868 GDFTGSGDVSGHLDFSGQLSGDR----ASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDE 923 +T + + + SG L ++G P L + T+ G +S Sbjct: 292 PGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQS------- 344 Query: 924 ERIEWPSTPTVGELPSG--AEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEV 981 WPS+ PSG + ++ S + S P+ +S Sbjct: 345 ----WPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASS--------------- 385 Query: 982 LETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTA----PGVEDISGLPSGE 1037 TT E+ + + S V T P SG V E+TA PG P Sbjct: 386 --TTLGHSEESTPVHSSPVATATTP--PPARSATSGHVEESTAYHRSPGSTQTMHFPES- 440 Query: 1038 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLE 1097 +T G + S G T S PS TTA G Sbjct: 441 ---STTSGHSEESATFHGSTTHTK-------SSTPS-----TTAALAHTSYHSSLGSTET 485 Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157 T ISG ++P + LP+G + G S + SG + TA Sbjct: 486 THFRDSSTISGRSEESKASHSSPDAMATTVLPAGST-PSVLVGDSTPSPISSGSMETTAL 544 Query: 1158 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217 PG GL ++P D + LP+ + + S G TA PG Sbjct: 545 PGSTTKPGLSEKSTTFYSSPRSPDTTHLPAS-MTSSGVSEESTTSHSRPGSTHTTAFPGS 603 Query: 1218 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1277 + GL ++PG D + P + P P G T P Sbjct: 604 TTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP-GSTETTLLPDNTTA 662 Query: 1278 SGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDE-ISGLPSGEVLETTAPGVEEISG 1336 SGL + ++ + P+G TT G PS P Sbjct: 663 SGLLEASMPVHSSTRSPHTTLSPAGS---TTRQGESTTFHSWPSSNDTRPAPPTT----- 714 Query: 1337 LPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELP 1396 + +E ST++ G S +P+ +S SGL S+ G P Sbjct: 715 --TSAFVEPSTTSHGSPSSIPT------THISARSTTSGLVEESTTYHSSPGSTQTMHFP 766 Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP 1456 + TS G E + S + + S L P+ S + S Sbjct: 767 ESD--TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 824 Query: 1457 SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFS 1516 SGR ++ ++D +G L ++ + LG+ + + SG ET+ LP Sbjct: 825 SGRSEESIASHSSQDATGTIV----LPARSTNSVLLGESTTSPISSGSM-ETTALP---- 875 Query: 1517 GEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAG 1576 GS GL + S P +TL T S+ E + G+ Sbjct: 876 --------GSTTTPGLSERSTTFHSSPRSPA--TTLSPASTTSSGVSEESTTSHSRPGST 925 Query: 1577 EISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETS 1636 + P S GL + S + GS D + +P + G P TS +S Sbjct: 926 HTTAFPDSTT-----TPGLSRHSTTSHSSPGSTDTT-LLPA--STTTXLVGEPTTSPISS 977 Query: 1637 GVTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG-- 1690 G TE + L S+ G+S E S Y + S ++ S +SGV + S PG Sbjct: 978 GSTETTALPGSTTTAGLS-EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1036 Query: 1691 ----FSGATSGVPDLVSGTTSGSGESSGITFVD---TSLVEVAPTTFKEEEGLGSVELSG 1743 F G+T+ T S S S T + T+ + P + G GS E + Sbjct: 1037 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTL 1096 Query: 1744 LPSGEADLSGKSGMVDVS-------GQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSR 1796 LP D + SG+++ S G T+ +G T++ E + S + + Sbjct: 1097 LP----DNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1152 Query: 1797 AEIGSSLPSGAYYGSGTPSSFPTVSLV----------DRTLVESVTQAP--TAQEAGEGP 1844 S+ + G+PSS PT + T V S AP T A Sbjct: 1153 PTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTT 1212 Query: 1845 SGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGES 1904 SG++E S A+ +P S + F + S E T + STT+ E Sbjct: 1213 SGLVEESTAYHSSPG-STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 1271 Query: 1905 SVAMGTSGEASGLPEVTLITSEFVEGVT------EPTISQELGQRPPVTHTPQLFESSGK 1958 + +S + + T+ F E T E T S +T P F +SG+ Sbjct: 1272 PTSYHSSPGS-------IATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGR 1324 Query: 1959 V--STAGDIS--------GATPVLPG-------------------SGVEVSSVPESSSET 1989 + ST IS +T PG S ++S S T Sbjct: 1325 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPT 1384 Query: 1990 SAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSG-STLTFQEGEAS 2048 S Y +A + A AS SG LS+ ++ FH + L +T +F + + Sbjct: 1385 SLYSQAESTHTTAFPASTTTSG---LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTT 1441 Query: 2049 AAPEVSGESTTTSDVGTEAPGLPSATPT--ASGDRTEISGDLSGHTSQLGVVISTSIPES 2106 + +T S T PGL + T +S TE + +T + ST P+S Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDS 1501 Query: 2107 EWTQQTQRPAE---THLEIESSSLLYSGEETHTV---------ETATSPTDASIPASPEW 2154 T PA T + ES++ S + T T + PT I SP + Sbjct: 1502 PGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTY 1561 Query: 2155 KR---ESESTAAAPARSC----------------AEEPCGAGTCKETE--GHVICLCPPG 2193 S ST+ S + E G C+E + C+CP G Sbjct: 1562 TTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQG 1621 Query: 2194 YTGEHC 2199 Y G C Sbjct: 1622 YVGYQC 1627 Score = 62.8 bits (151), Expect = 4e-09 Identities = 130/538 (24%), Positives = 193/538 (35%), Gaps = 66/538 (12%) Query: 1632 SGETSGVTELSGLSSGQPGISG-------EASGVLYGTSQPFGITDLSGETSGVPDLSGQ 1684 S SG +E S +S PG +G A+ V G + IT S ET+ +P S Sbjct: 135 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPG-STT 193 Query: 1685 PSGLPG-----FSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT---TFKEEEGL 1736 +GL +S S L T+ SG S T TS PT F + Sbjct: 194 TAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKST---TSHSRPGPTHTIAFPD---- 246 Query: 1737 GSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSR 1796 S + G+ G D + GT S ++ F P G + Sbjct: 247 -STTMPGVSQESTASHSIPGSTDTTLS-PGTTTPSSLGPESTTFHSSP-------GYTKT 297 Query: 1797 AEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHS 1855 + + + + TP T S T +P + EG P+ + Sbjct: 298 TRLPDNTTTSGLLEASTPVHSSTGS-------PHTTLSPASSTTHEGEPTTFQSWPSSKD 350 Query: 1856 GAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEAS 1915 +P SG S F+ LS PS P T +FS +STT E S + +S A+ Sbjct: 351 TSPAPSGTTSAFVKLSTTYHS--SPSSTP--TTHFSA--SSTTLGHSEESTPVHSSPVAT 404 Query: 1916 GL--PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLP 1973 P TS VE E T H P+ +SG + G+T Sbjct: 405 ATTPPPARSATSGHVE---ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK 461 Query: 1974 GSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL 2033 S S + + TS + G S R+ S SE + A H + ++ + Sbjct: 462 SS---TPSTTAALAHTSYHSSLG---STETTHFRDSSTISGRSEESKASHSSPDAMATTV 515 Query: 2034 GVSGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGDRTEISGDLSGHT 2092 +GST + G+++ +P SG TT+ G T PGL + T S S T Sbjct: 516 LPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF------YSSPRSPDT 569 Query: 2093 SQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSG--EETHTVETATSPTDASI 2148 + L +++S E T RP TH S G +E+ ++ PTD ++ Sbjct: 570 THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL 627 Score = 38.1 bits (87), Expect = 0.11 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 20/165 (12%) Query: 1994 EAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLG----VSGSTLTFQEG---E 2046 E A A + +E S SPD+SE T+ HE + S ++GST+ G Sbjct: 40 EQARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTT 99 Query: 2047 ASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPES 2106 +++ P S TT SD G + +T T S SGH+ + +S S P + Sbjct: 100 SASTPSSSDPFTTFSDYGVSVTFITGSTAT---KHFLDSSTNSGHSEE--STVSHSGPGA 154 Query: 2107 EWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPAS 2151 T T S++ ++ GE + T+ S ++P S Sbjct: 155 TGT--------TLFPSHSATSVFVGEPKTSPITSASMETTALPGS 191 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 119 bits (297), Expect = 5e-26 Identities = 380/1641 (23%), Positives = 557/1641 (33%), Gaps = 196/1641 (11%) Query: 627 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT---GLPDPLSRHHAFCFRGISAVPSP 683 L+ GS + P PG L P+ T GL + + H+ + + Sbjct: 1761 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 1820 Query: 684 GE--EEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTE 741 G +G + T S P + VE TT+ S +T F+ Sbjct: 1821 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 1880 Query: 742 WEPAYT----PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSE 797 E + T PV T+ P P T EEST S+ P S SE Sbjct: 1881 SEESTTVHSSPVATATTPS--PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 1938 Query: 798 EPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSS 857 E S P PS + EEP++ Y SP + T P S Sbjct: 1939 ESRTSHSSTTHTISSP-----------PSTTSALVEEPTS----YHSSPGSTATTHFPDS 1983 Query: 858 GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESG 917 SG + S S D +G + + + G + SSG T + LP + Sbjct: 1984 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET--TALPGSTT 2041 Query: 918 LPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGL 976 P E+ + S+P + S A S S G T+ GL Sbjct: 2042 TPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 2101 Query: 977 PSGEVLETTAPGVEDISGLP-----SGEVLETT----APGVEDISGLPSGEVL-----ET 1022 ++PG D + LP SG E+T +PG D + P E+ Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 2161 Query: 1023 T----APGVEDISGLPSGEVLETTAPGVEDISGL---PSGEVLETTAPGVEDISGLPSGE 1075 T +PG + P TT+ G+ + S +G T +P GL Sbjct: 2162 TTFHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 2217 Query: 1076 VLETTAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEV 1133 T P + P TA VE+ + G T P SG Sbjct: 2218 TAFQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2273 Query: 1134 LETAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1192 + ++P D SG PS T+ G S + G T PG GL Sbjct: 2274 IFHSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2330 Query: 1193 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-GEVLETAAPGVEDISGLPS-GEVLET 1250 ++P + P+ + + G E + G T +P GL + + Sbjct: 2331 YSSPRSPTTTLSPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 2388 Query: 1251 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTA- 1309 ++PG + + P T+ G E + TT + + SG E+TA Sbjct: 2389 SSPGSTETTVFPRTPT--TSVRGEEPTTFHSRPASTHTTLFTEDSTT---SGLTEESTAF 2443 Query: 1310 PG--VDEISGLPSGEVLETTAPGVEEISGLPS--GEVLETSTSAVGDLSGLPSGGEVLEI 1365 PG +GLP+ TTA EE + PS G T + A SGL + Sbjct: 2444 PGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL 2500 Query: 1366 SVSGVED--ISGLPSGEVVETSASGIEDVSELPSG--EGLETSASGVEDLSRLPSGEEVL 1421 S S E + G P+ + ++ P T++SGV + S S + Sbjct: 2501 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-SHSQPG 2559 Query: 1422 EISASGFGDLSGLPSGGEGLETSASEVG-TDLSGLPSGREGLETSASGAEDLSGLPSGKE 1480 + F D + P TS S G TD + LP+ T+ SG PS + Sbjct: 2560 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS-----TTTSG-------PSQES 2607 Query: 1481 DLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGL-- 1538 S+ G D P T E++ S ++ + S SG+ + S Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVH 2667 Query: 1539 -PSGFP--TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASG- 1594 +G P T+S ST + ST + T + P E R+ G Sbjct: 2668 SSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 2727 Query: 1595 -----LPSGTELSGQAS------GSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSG 1643 P+ + SG + SPD SG P + G TS + G TE++ Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787 Query: 1644 L--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG-----FSGA 1694 L S+ PG+S EAS Y + S ++ S + GV + S PG S A Sbjct: 2788 LPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846 Query: 1695 TSGVPDLVSGTTSGSGESSGIT-------FVDTSLVEVAPTTFKEEEGLGSVEL------ 1741 ++ P L +T+ S G T TS+ PTTF L Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST 2906 Query: 1742 -SGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-PEFSGLPSGIAEVSGESSRAEI 1799 SGL G + T G S T P SG + ++ + Sbjct: 2907 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV 2966 Query: 1800 GSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQ-------APTAQEAGEGP-----SGI 1847 G S PS +PSS T +L S+++ +P + +A P SG+ Sbjct: 2967 GESTPSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021 Query: 1848 LELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVA 1907 E S P + H+ S SGL S EP + G +T + ++ + Sbjct: 3022 SEESSTSHSQPGST--HTTAFPDSTTTSGL---SQEPTASHSSQGSTEATLSPGSTTASS 3076 Query: 1908 MG----TSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAG 1963 +G T + G E TL+ + TI+ L + TH+ S+G + T Sbjct: 3077 LGQQSTTFHSSPGDTETTLLPDD--------TITSGLVEASTPTHS-----STGSLHTTL 3123 Query: 1964 DISGATPV-LPGSGVEVSSVPESSSETSAYPEAGFGASAAP-EASREDSGSPDLSETT-- 2019 + +T L S P SS T + P G +AAP E S P + TT Sbjct: 3124 TPASSTSAGLQEESTTFQSWPSSSDTTPSPP----GTTAAPVEVSTTYHSRPSSTPTTHF 3179 Query: 2020 --SAFHEANLERSSGLGVS-GSTLTFQEGEASAAPEVSGESTTT--SDVGTEAPGLPSAT 2074 S+ E S+ + S G+T T SA + GE TT+ S TE LP +T Sbjct: 3180 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 3239 Query: 2075 PTAS---GDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSG 2131 TA T S S T+ ++S E T RP TH S G Sbjct: 3240 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 3299 Query: 2132 EETHTVETATSPTDASIPASP 2152 + + +SP SP Sbjct: 3300 VSQESTASHSSPGSTDTTLSP 3320 Score = 116 bits (290), Expect = 3e-25 Identities = 374/1601 (23%), Positives = 530/1601 (33%), Gaps = 248/1601 (15%) Query: 678 SAVPSPGEEEGGTPTSPSGVEEWIVTQ----------VVPGVAAVP-VEEETTA---VPS 723 S+ SP T+ SGV E T P +P V +E+TA +P Sbjct: 285 SSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG 344 Query: 724 GETTAILEFTTEP-----ENQT-EWEPAYTPVGTSPLPGILPTWPPTGAAT--EESTEGP 775 T + TT P E+ T P YT T+ LP T A+T ST P Sbjct: 345 STDTTLSPGTTTPSSLGPESTTFHSSPGYTK--TTRLPDNTTTSGLLEASTPVHSSTGSP 402 Query: 776 SATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEP 835 T PS+S F S S P PS V+L + PS P+ Sbjct: 403 HTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA 462 Query: 836 SA-----SEE--PYTPSPPVPSWTELPSSGEESGAPDVSG------------DFTGSGDV 876 S+ SEE P SP + T P+ SG + S F S Sbjct: 463 SSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTT 522 Query: 877 SGHLDFSGQLSGDRA---SGLPS--GDLDSSGLTSTVGSGLPV---ESGLPSGDEERIE- 927 SGH + S G S PS L + S++GS +S SG E + Sbjct: 523 SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582 Query: 928 ---WPSTPTVGELPSGA--EILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVL 982 P LP+G+ +L G ++ S + SG + T+ G GL Sbjct: 583 SHSSPDAMATTVLPAGSTPSVLVGDSTP----SPISSGSMETTALPGSTTKPGLSEKSTT 638 Query: 983 ETTAPGVEDISGLPSGEVLETTAPGVED---ISGLPSGEVLETTAPGVEDISGLPSGEVL 1039 ++P D + LP+ T+ GV + S G T PG + GL Sbjct: 639 FYSSPRSPDTTHLPA----SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 694 Query: 1040 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETA 1099 ++PG D + P + P P G T P SGL + + Sbjct: 695 SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP-GSTETTLLPDNTTASGLLEASMPVHS 753 Query: 1100 APGVEDISGLPSGEVLETAA-------PGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1152 + + P+G P +D P P G PS + Sbjct: 754 STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS-HGSPS-SI 811 Query: 1153 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1212 T SGL ++PG P + T+ G E + S + Sbjct: 812 PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT--TSGRGEESTTSHSSTTHTIS 869 Query: 1213 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL------ETAAPGVEDISG---LPS 1263 +AP S L ++PG + P TA+ +D +G LP+ Sbjct: 870 SAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 927 Query: 1264 GEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEV 1323 G S + SG + T PG GL ++P + P+ Sbjct: 928 RSTTSVLL-GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA--- 983 Query: 1324 LETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVE 1383 TT+ GV E S T T+A D + P GL Sbjct: 984 -STTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP-----------------GLSRHSTTS 1025 Query: 1384 TSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLET 1443 S+ G D + LP+ T+ SG PS E S+SG D + P T Sbjct: 1026 HSSPGSTDTTLLPA----STTTSG-------PSQESTTSHSSSGSTDTALSPG-----ST 1069 Query: 1444 SASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSG 1503 +A G + + S T+ S V S++G P TL Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS------PRTTL--- 1120 Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563 +P +S P G GE + F P+ T ST V ST Sbjct: 1121 -SPASSTSP-GLQGESTA-------------FQTHPASTHTTPSPPSTATAPVEESTTYH 1165 Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSG 1623 T P++ S SG +E S SPD SG P + Sbjct: 1166 RSPGST------------PTTHFPASSTTSG---HSEKSTIFHSSPDASGTTPSSAHSTT 1210 Query: 1624 QPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVP 1679 G TS + G TE++ L S+ PG+S EAS Y + S ++ S + GV Sbjct: 1211 SGRGESTTSRISPGSTEITTLPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVG 1269 Query: 1680 DLSGQPSGLPG-----FSGATSGVPDLVSGTTSGSGESSGIT-------FVDTSLVEVAP 1727 + S PG S A++ P L +T+ S G T TS+ P Sbjct: 1270 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329 Query: 1728 TTFKEEEGLGSVEL-------SGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-PE 1779 TTF L SGL G + T G S T P Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389 Query: 1780 FSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQ------ 1833 SG + ++ +G S PS +PSS T +L S+++ Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFY 1444 Query: 1834 -APTAQEAGEGP-----SGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887 +P + +A P SG+ E S P H+ S S L S EP + Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQP--GSTHTTAFPDSTTTSDL---SQEPTTS 1499 Query: 1888 PYFSGDFASTTNVSGESSVAMG----TSGEASGLPEVTLITSEFVEGVTEPTISQELGQR 1943 G +T + ++ ++G T + G E TL+ + TI+ L + Sbjct: 1500 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD--------TITSGLVEA 1551 Query: 1944 PPVTHTPQLFESSGKV-STAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAA 2002 TH+ S+G + +T S + L S P SS T + P G +AA Sbjct: 1552 STPTHS-----STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP----GTTAA 1602 Query: 2003 P-EASREDSGSPDLSETT----SAFHEANLERSSGLGVS-GSTLTFQEGEASAAPEVSGE 2056 P E S P + TT S+ E S+ + S G+T T SA + GE Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662 Query: 2057 STTT--SDVGTEAPGLPSATPTA---SGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQ 2111 TT+ S TE LP +T TA T S S T+ ++S E T Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1722 Query: 2112 TQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASP 2152 RP TH S G + + +SP SP Sbjct: 1723 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1763 Score = 115 bits (287), Expect = 7e-25 Identities = 358/1588 (22%), Positives = 541/1588 (34%), Gaps = 200/1588 (12%) Query: 682 SPGEEEGGTPTSP----SGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPE 737 S + G TP+S SG E +++ PG + +T P G + A F + P Sbjct: 2751 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP-GLSEASTTFYSSPR 2809 Query: 738 NQTEWEPAYTPVGTSPLP-GILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPS 796 + T +P + L G T + + ST P++T P SEE + S Sbjct: 2810 SPTT---TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY----S 2862 Query: 797 EEPSPSEEPFPSVRPFPSVELFPSEEP--FPSKEPSP-----SEEPSAS----EEPYTPS 845 P +E +V P + EEP F S+ S +E+ + S E P Sbjct: 2863 SSPGSTET---TVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 2919 Query: 846 PPVPSWTELPSS------GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDL 899 P + T LP++ GEES S TG+ SG + S L Sbjct: 2920 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2979 Query: 900 DSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959 +++ L G P L P +P P+ ++SGV + S Sbjct: 2980 ETTTLP-----GSPTTPSLSEKSTTFYTSPRSPDATLSPATT-----TSSGVSEESSTSH 3029 Query: 960 GEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEV 1019 + T + D S SG E TA S G T +PG S L Sbjct: 3030 SQPGSTHTTAFPD-STTTSGLSQEPTA------SHSSQGSTEATLSPGSTTASSLGQQST 3082 Query: 1020 LETTAPGVEDISGLPSGEVLETTAPGVEDISG---LPSGEVLETTAPGVEDISGLPSGEV 1076 ++PG + + LP +T G+ + S +G + T P +GL Sbjct: 3083 TFHSSPGDTETTLLPD----DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 3138 Query: 1077 LETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS---GLPSGEV 1133 + P D + P G TAAP ++S T S G Sbjct: 3139 TFQSWPSSSDTTPSPPGT---TAAP--VEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 3193 Query: 1134 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1193 ++PG + P+ G S + SG TA PG +GL Sbjct: 3194 TVHSSPGATGTALFPTRSATSVLV-GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252 Query: 1194 AAPGVEDISGLPSGEVLETAAPGVEDISGLPS---GEVLETAAPGVEDISGLPSGEVLET 1250 ++P D + P+ T + GV + S G TA PG + G+ Sbjct: 3253 SSPRSPDTTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 3308 Query: 1251 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAP 1310 ++PG D + P + P P G T P SGL ++ Sbjct: 3309 SSPGSTDTTLSPGSTTASSLGPESTTFHSGP-GSTETTLLPDNTTASGLLEASTPVHSST 3367 Query: 1311 GVDEISGLPSGEVL---ETTA----PGVEEISGLPSGEVLETSTSAVGDLS----GLPSG 1359 G + P+G E+T P ++ + P T+TSA +LS G PS Sbjct: 3368 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPP-----TTTSAFVELSTTSHGSPSS 3422 Query: 1360 GEVLEISVSGV-----EDISGLPSGEVV---------ETSASGIEDVSELPSGEGLETSA 1405 S S E+ + + S V T++ +E+ + S G + Sbjct: 3423 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM 3482 Query: 1406 SGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGL--------ETSASEVGTDL--SGL 1455 E + GEE +S +S PS L + S T S Sbjct: 3483 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 3542 Query: 1456 PSGREGLETSASGAEDLSG---LPS--------GKEDLVGSASGDLDLGKLPSGTLGSGQ 1504 SGR T++ ++D +G LP+ G+ +SG ++ LP T G Sbjct: 3543 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 3602 Query: 1505 APETSGLPSGFSGEYSGVDLGSGPPSGLPDFS----GLPSGFPTVSLVDSTLVEVVTAST 1560 + +++ S + + S SG+ + S P T + DST T Sbjct: 3603 SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST--------T 3654 Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620 L T S G ++ L S SG + S +SGS D + Sbjct: 3655 TPGLSRHSTTSHSSPGSTD---TTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTA 3711 Query: 1621 VS-GQPSG-FPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGV 1678 +S GQ S F + G T T L S+ GI ++ V T P T LS +S Sbjct: 3712 LSFGQESTTFHSSPGSTH--TTLFPDSTTSSGIVEASTRVHSSTGSPR--TTLSPASSTS 3767 Query: 1679 PDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGS 1738 P L G+ + +T P S T+ ES TT+ G Sbjct: 3768 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEES---------------TTYHRSPGSTP 3812 Query: 1739 VELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGE----- 1793 S + S KS + S SGT SS ++ + S I+ S E Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 3872 Query: 1794 SSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGA 1853 S G S S +Y S P S PT +L ++ + + S +S A Sbjct: 3873 GSTTTPGLSEASTTFYSS--PRS-PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929 Query: 1854 HSGAPDMSGEHSGFLDLS-GLQSGLIEPSG-------EPPGTPYFSGDFASTTNVSGESS 1905 + P +S E + S G + P E P T + S ++ T + E S Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEP-TTFHSRPASTHTTLFTEDS 3988 Query: 1906 VAMGTSGEASGLP----------EVTLITSEF-VEGVTEPTISQELGQR-PPVTHTPQLF 1953 G + E++ P TL T++ E T P+ S G + P T Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048 Query: 1954 ESSGKVSTAGDISGATPVLPGSGVEVSSVPESSS--ETSAYPEAGFGASAAPEASREDSG 2011 S S T LPGS S +S++ + P+A + + + Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108 Query: 2012 SPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLP 2071 S S+ S A + ++ G+S T + S +S STT S +G ++ Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168 Query: 2072 SA----TPTASGDRTEISGDLSGHT---SQLGVVISTSIPESEWTQQTQRPAETHLEIES 2124 S+ T D T SG + T S G + +T P S + Q + T S Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228 Query: 2125 SS-LLYSGEETHTVETATSPTDASIPAS 2151 SS S T V S T S P+S Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSS 4256 Score = 114 bits (286), Expect = 9e-25 Identities = 350/1609 (21%), Positives = 528/1609 (32%), Gaps = 246/1609 (15%) Query: 713 PVEEETTAVPSGETTA--ILEFTTEPENQTEWEPAYTPVGTSPL------------PG-- 756 P +TT +P+ TT+ E TT + + A +P T+ L PG Sbjct: 3669 PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGST 3728 Query: 757 ---ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFP 813 + P + E ST S+T P + P+ S P E + + S P Sbjct: 3729 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP 3788 Query: 814 SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873 S PS +P EE + Y SP T P+S SG + S F S Sbjct: 3789 SP---------PSTATAPVEESTT----YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 3835 Query: 874 GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933 D SG S + + + T G GL P +PT Sbjct: 3836 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 3895 Query: 934 VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993 P+ ++ L GE TS S G S TT PG+ + S Sbjct: 3896 TTLSPAS-------------MTSLGVGEESTTSRSQPGSTHSTVSPA--STTTPGLSEES 3940 Query: 994 GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053 + +++PG + + P TT+ E+ + S T ED + Sbjct: 3941 -----TTVYSSSPGSTETTVFPRST---TTSVRREEPTTFHSRPASTHTTLFTEDST--T 3990 Query: 1054 SGEVLETTA-PG--VEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETAAPGVEDISG 1108 SG E+TA PG +GLP+ TTA E+ + PS G +P SG Sbjct: 3991 SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 4047 Query: 1109 LPSGEVLETAAPGVEDISGLPSGEVLET---------AAPGVEDISGLPSGEVLETAAPG 1159 L +P + + LP + +P D + P+ T + G Sbjct: 4048 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA----TTTSSG 4103 Query: 1160 VEDISGLPS---GEVLETAAPGVEDISGLPS---------GEVLETAAPGVEDISGLPSG 1207 V + S G TA P SGL G T +PG S L Sbjct: 4104 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 4163 Query: 1208 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISG---LPSGEVLETAAPGVEDISGLPSG 1264 ++PG + + LP +T G+ + S +G + T P +GL Sbjct: 4164 STTFHSSPGDTETTLLPD----DTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEE 4219 Query: 1265 EVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVL 1324 + P D + P TTA VE + S T + L E Sbjct: 4220 STTFQSWPSSSDTTPSPPS----TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 4275 Query: 1325 ET--TAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVV 1382 T ++PG +G L + SA L G P+ + SG + + LP Sbjct: 4276 TTVHSSPGA-------TGTALFPTRSATSVLVGEPTTSPIS----SGSTETTALPGS--- 4321 Query: 1383 ETSASGIEDVSEL--PSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440 T+ +G+ + S S +T+ S S S E S G + PS Sbjct: 4322 -TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSS--- 4377 Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500 T+ V + + S +T+ S + + S+ G + LP T Sbjct: 4378 --TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 4435 Query: 1501 GSGQAPETSGLPSGFSGEYSGVD-LGSGPPSG-LPDFSGLPSGFPTVSLVDSTLVEVVTA 1558 SG ++ + S ++ + GS G F P+ T +T V Sbjct: 4436 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 4495 Query: 1559 STASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGL 1618 ST S G S P++ S G +E S SP + P Sbjct: 4496 STTSH------------GSPSSTPTTHFSASSTTLGR---SEESTTVHSSPVATATTPS- 4539 Query: 1619 FGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGV 1678 TSG+ E S PG + T+ G + +S Sbjct: 4540 -----------PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTT 4588 Query: 1679 PDLSGQPS-------------GLPGFSGATSGVPDLVSGTTSGSGESSGITFV--DTSLV 1723 +S PS PG S AT+ PD S TTSG E S + D + Sbjct: 4589 HTISSAPSTTSALVEEPTSYHSSPG-STATTHFPD--SSTTSGRSEESTASHSSQDATGT 4645 Query: 1724 EVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGL 1783 V P LG S + SG + + G+ + G + ++ F Sbjct: 4646 IVLPARSTTSVLLGESTTSPISSGSMETTA----------LPGSTTTPGLSEKSTTFHSS 4695 Query: 1784 PSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG 1843 PS +S +G S S + S P + T R+ + + TA + G Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSS--PVATATTPSPARSTTSGLVEESTAYHSSPG 4753 Query: 1844 PSGIL---ELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNV 1900 + + E S A + + HS E P T Y S + T Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP-TSYHSSPGSIATTH 4812 Query: 1901 SGESSVAMGTSGEASGLPEVTLITSEFVEGVTEP----TISQELGQRPPVTHTPQLFESS 1956 ESS G S E++ +S G+T T S + + +P E++ Sbjct: 4813 FPESSTTSGRSEESTASH-----SSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 4867 Query: 1957 -GKVSTAGDISGATPVLPGSG---------VEVSSVPESSSETSAYPEAGFGASAAPEAS 2006 +T +S + +L S ++S S TS Y +A + A AS Sbjct: 4868 LASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAS 4927 Query: 2007 REDSGSPDLSETTSAFHEANLERSSGLGVSG-STLTFQEGEASAAPEVSGESTTTSDVGT 2065 SG LS+ ++ FH + L +T +F + + + +T S T Sbjct: 4928 TTTSG---LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPAST 4984 Query: 2066 EAPGLPSATPT--ASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAE---THL 2120 PGL + T +S TE + +T + ST P+S T PA T + Sbjct: 4985 TVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDI 5044 Query: 2121 EIESSSLLYSGEETHTV---------ETATSPTDASIPASPEWKR---ESESTAAAPARS 2168 ES++ S + T T + PT I SP + S ST+ S Sbjct: 5045 GQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEES 5104 Query: 2169 C----------------AEEPCGAGTCKETE--GHVICLCPPGYTGEHC 2199 + E G C+E + C+CP GY G C Sbjct: 5105 TTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGYVGYQC 5153 Score = 112 bits (280), Expect = 4e-24 Identities = 353/1560 (22%), Positives = 524/1560 (33%), Gaps = 248/1560 (15%) Query: 713 PVEEETTAVPSGETTA--ILEFTTEPENQTEWEPAYTPVGTSPL------------PG-- 756 P +TT +P+ TT+ E TT + + A +P T+ L PG Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2171 Query: 757 ---ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFP 813 + P + E ST S+T P + P+ S P E + + S P Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP 2231 Query: 814 SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873 S PS +P EE + Y SP T P+S SG + S F S Sbjct: 2232 SP---------PSTATAPVEESTT----YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 2278 Query: 874 GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933 D SG S + + + T G GL P +PT Sbjct: 2279 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2338 Query: 934 VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993 P+ ++ L GE TS S G S TT PG+ + S Sbjct: 2339 TTLSPAS-------------MTSLGVGEESTTSRSQPGSTHSTVSPA--STTTPGLSEES 2383 Query: 994 GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053 + +++PG + + P TT+ E+ + S T ED + Sbjct: 2384 -----TTVYSSSPGSTETTVFPR---TPTTSVRGEEPTTFHSRPASTHTTLFTEDST--T 2433 Query: 1054 SGEVLETTA-PG--VEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETAAPGVEDISG 1108 SG E+TA PG +GLP+ TTA E+ + PS G T +P SG Sbjct: 2434 SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490 Query: 1109 LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS 1168 L +P + + LP + + P T +P SG+ Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA-TLSPATTTSSGVSE 2549 Query: 1169 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228 + PG + P T PG+ S ++PG D + LP+ Sbjct: 2550 ESSTSHSQPGSTHTTAFPDS----TTTPGLSRHS------TTSHSSPGSTDTTLLPASTT 2599 Query: 1229 LETAAPGVEDISGLPSGEVLETA-APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1287 T+ P E + S +TA +PG ++PG + P Sbjct: 2600 --TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---- 2653 Query: 1288 TTAPGVEEISGL---PSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEV-- 1342 TT+ G+ E S +G T +P GL T P + P Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATA 2713 Query: 1343 -LETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGL 1401 +E ST+ P+ + SG + S + ASG PS Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS---PDASGTT-----PSSAHS 2765 Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLS--GLPSGR 1459 TS G SR+ G + + G GL +S T LS + S Sbjct: 2766 TTSGRGESTTSRISPGSTEIT-TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2824 Query: 1460 EGLETSASGAEDLS-------------GLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAP 1506 G E++ S ++ S GL + S+ G + P T S + Sbjct: 2825 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGE 2884 Query: 1507 ETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEG 1566 E + S + ++ + SGL + S G P ST + T ++L Sbjct: 2885 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA-----STQTGLPATLTTADLGE 2939 Query: 1567 RGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPS 1626 T S +G S + G + + LS ++ + + G P +S + + Sbjct: 2940 ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKST 2998 Query: 1627 GF------PDTS-----GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGET 1675 F PD + +SGV+E S S QPG + + T+ P T T Sbjct: 2999 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST-------HTTAFPDSTT-----T 3046 Query: 1676 SGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEG 1735 SG LS +P+ G+T S T S G+ S TTF G Sbjct: 3047 SG---LSQEPTASHSSQGSTEATLSPGSTTASSLGQQS--------------TTFHSSPG 3089 Query: 1736 LGSVELSGLPSGEADLSGKSGMVDVS-------GQFSGTVD-----SSGFTSQTPEFSGL 1783 E + LP D + SG+V+ S G T+ S+G ++ F Sbjct: 3090 --DTETTLLP----DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 3143 Query: 1784 PSGIAEVSGESSRAEIGSSLP----SGAYYGSGTPSSFPTV--SLVDRTLVESVTQAPTA 1837 PS S +++ + G++ S Y+ PSS PT S TL S Sbjct: 3144 PS-----SSDTTPSPPGTTAAPVEVSTTYHSR--PSSTPTTHFSASSTTLGRSEESTTVH 3196 Query: 1838 QEAGEGPSGILELSGAHS---GAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDF 1894 G + + A S G P S SG + + L T ++S Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 3256 Query: 1895 ASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFE 1954 + T +S S+ + G S E++ TS G T T P V+ E Sbjct: 3257 SPDTTLSPASTTSSGVSEEST--------TSHSRPGSTHTTAFPGSTTMPGVSQ-----E 3303 Query: 1955 SSGKVSTAGDISGATPVLPGSGVEVSSVPES--------SSETSAYPEAGFGASAAPEAS 2006 S+ S+ G S T + PGS S PES S+ET+ P+ AS EAS Sbjct: 3304 STASHSSPG--STDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPD-NTTASGLLEAS 3360 Query: 2007 REDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTS--DVG 2064 S TT L + G + TFQ S + +TT++ ++ Sbjct: 3361 TPVHSSTGSPHTT-------LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 3413 Query: 2065 TEAPGLPSATPTA--SGDRTEISGDLSGHTSQLGVVISTSIPE----------SEWTQQT 2112 T + G PS+TPT S T + T V + + P E T Sbjct: 3414 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYH 3473 Query: 2113 QRPAETHLEI--ESSSLLYSGEE--------THTVETATSPTDASIPASPEWKRESESTA 2162 P T ES + GEE THT+ +A S T A + + STA Sbjct: 3474 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA 3533 Score = 108 bits (271), Expect = 5e-23 Identities = 361/1554 (23%), Positives = 535/1554 (34%), Gaps = 216/1554 (13%) Query: 682 SPGEEEGGTPTSP----SGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPE 737 S + G TP+S SG E +++ PG + +T P G + A F + P Sbjct: 2277 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP-GLSEASTTFYSSPR 2335 Query: 738 NQTEWEPAYTPVGTSPLP-GILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPS 796 + T +P + L G T + + ST P++T P SEE S + S Sbjct: 2336 SPTT---TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE---STTVYSS 2389 Query: 797 EEPSPSEEPFPSVRPFPSVELFPSEEP--FPSKEPSP-----SEEPSAS----EEPYTPS 845 S FP P SV EEP F S+ S +E+ + S E P Sbjct: 2390 SPGSTETTVFPRT-PTTSVR---GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 2445 Query: 846 PPVPSWTELPSS------GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDL 899 P + T LP++ GEES S TG+ SG + S L Sbjct: 2446 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2505 Query: 900 DSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959 +++ L G P L P +P P+ ++SGV + S Sbjct: 2506 ETTTLP-----GSPTTPSLSEKSTTFYTSPRSPDATLSPATT-----TSSGVSEESSTSH 2555 Query: 960 GEVLETSASGVGDLSGLPSGEVLETTA---PGVEDISGLP-----SGEVLETT----APG 1007 + T + D + P TT+ PG D + LP SG E+T +PG Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615 Query: 1008 VEDISGLPSGEVL-----ETT----APGVEDISGLPSGEVLETTAPGVEDISGL---PSG 1055 D + P E+T +PG + P TT+ G+ + S +G Sbjct: 2616 STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTG 2671 Query: 1056 EVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGE 1113 T +P GL T P + P TA VE+ + G Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGS 2727 Query: 1114 VLETAAPGVEDISGLPSGEVLETAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVL 1172 T P SG + ++P D SG PS T+ G S + G Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTE 2784 Query: 1173 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-GEVLET 1231 T PG GL ++P + P+ + + G E + G T Sbjct: 2785 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS--MTSLGVGEESTTSRSQPGSTHST 2842 Query: 1232 AAPGVEDISGLPS-GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTA 1290 +P GL + +++PG + + P T+ G E + TT Sbjct: 2843 VSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTT--TSVRGEEPTTFHSRPASTHTTL 2900 Query: 1291 PGVEEISGLPSGEVLETTA-PG--VDEISGLPSGEVLETTAPGVEEISGLPS--GEVLET 1345 + + SG E+TA PG +GLP+ TTA EE + PS G T Sbjct: 2901 FTEDSTT---SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTT 2954 Query: 1346 STSAVGDLSGLPSGGEVLEISVSGVED--ISGLPSGEVVETSASGIEDVSELPSG--EGL 1401 + A SGL +S S E + G P+ + ++ P Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 3014 Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREG 1461 T++SGV + E S G + P T+ S + + + S + Sbjct: 3015 TTTSSGVSE-------ESSTSHSQPGSTHTTAFPDS-----TTTSGLSQEPTASHSSQGS 3062 Query: 1462 LETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSG 1521 E + S + + S+ GD + LP T+ SG ++ S ++ Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 3122 Query: 1522 VDLGSGPPSGLPD----FSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGE 1577 + S +GL + F PS T T V ST T + Sbjct: 3123 LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSAS 3182 Query: 1578 ISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSG 1637 + L SE + +S +GT L S + + GE P TS +SG Sbjct: 3183 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE--------------PTTSPISSG 3228 Query: 1638 VTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG--- 1690 TE + L S+ G+S E S Y + S ++ S +SGV + S PG Sbjct: 3229 STETTALPGSTTTAGLS-EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 3287 Query: 1691 ---FSGATSGVPDLVSGTTSGSGESSGITFVD---TSLVEVAPTTFKEEEGLGSVELSGL 1744 F G+T+ T S S S T + T+ + P + G GS E + L Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347 Query: 1745 PSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLP 1804 P D + SG+++ S + S P + P+G GES+ + S P Sbjct: 3348 P----DNTTASGLLEASTPVHSSTGS-------PHTTLSPAGSTTRQGESTTFQ---SWP 3393 Query: 1805 SGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQ-EAGEGPSGILELSGAHSGAPDMSGE 1863 + P++ + T S + PT A G E S +P + Sbjct: 3394 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 3453 Query: 1864 HSGFLDLSGLQSGLIEPS----GEPPGTPYFSGDFASTTNVSGESSVAM--GTSGEASGL 1917 SGL+E S P T + TT+ GE S T+ S Sbjct: 3454 TPS--PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 3511 Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKV--STAGDISG---ATPVL 1972 P T S VE EPT TH P +SG+ STA S T VL Sbjct: 3512 PSTT---SALVE---EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565 Query: 1973 PGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSG 2032 P +SV S TS +A P ++ +P LSE ++ FH + Sbjct: 3566 PARST--TSVLLGESTTSPISSGSMETTALPGSTT----TPGLSEKSTTFHSS------- 3612 Query: 2033 LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAP---GLPSATPTASGDRTEISGDLS 2089 S A +S STT+S V E+ P +T T + + + LS Sbjct: 3613 -------------PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 3659 Query: 2090 GHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSP 2143 H++ S S P S T T PA T S S + + +TA SP Sbjct: 3660 RHST-----TSHSSPGS--TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP 3706 Score = 108 bits (270), Expect = 6e-23 Identities = 353/1593 (22%), Positives = 525/1593 (32%), Gaps = 206/1593 (12%) Query: 670 HAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAV-------------PVEE 716 H F G + +P +E + +SP + T + PG P Sbjct: 675 HTTAFPGSTTMPGLSQESTASHSSPGPTD----TTLSPGSTTASSLGPEYTTFHSRPGST 730 Query: 717 ETTAVPSGETTAILEFTTEPENQTEWEPAYT--PVGTSPLPGILPT---WPPTGAATEES 771 ETT +P T + L + P + + P T P G++ G T WP + Sbjct: 731 ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAP 790 Query: 772 TEGPSATEVPSASEEPSPSEVP-------------------FPSEEPSPSEEPFP----- 807 SA PS + SPS +P + S S FP Sbjct: 791 PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 850 Query: 808 SVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVS 867 S R S S S PS + Y SP + T P S SG + S Sbjct: 851 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 910 Query: 868 GDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIE 927 S D +G + + + G + SSG T + LP + P E Sbjct: 911 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET--TALPGSTTTPGLSERSTT 968 Query: 928 WPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTA 986 + S+P + S A S S G T+ GL ++ Sbjct: 969 FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 1028 Query: 987 PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT-APGVEDISGLPSGEVLETTAPG 1045 PG D + LP+ T+ P E + S +T +PG + PG Sbjct: 1029 PGSTDTTLLPASTT--TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPG 1086 Query: 1046 VEDISGLPSGEVLETTAPGVEDISGL---PSGEVLETTAPGVEDISGLPSGEVLETAAPG 1102 + P TT+ G+ + S +G T +P GL P Sbjct: 1087 STHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 1142 Query: 1103 VEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1160 + P TA VE+ + G T P SG + ++P Sbjct: 1143 STHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP-- 1196 Query: 1161 EDISGL-PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1219 D SG PS T+ G S + G T PG GL ++P Sbjct: 1197 -DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 1255 Query: 1220 ISGLPSGEVLETAAPGVEDISGLPS-GEVLETAAPGVEDISGLPS-GEVLETAAPGVEDI 1277 + P+ + + G E + G T +P GL + +++ G + Sbjct: 1256 TTLSPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTET 1313 Query: 1278 SGLPSGEVLETTAPGVEEIS----------------GLPSGEVLETTA-PG--VDEISGL 1318 + P T+ G E + SG E+TA PG +GL Sbjct: 1314 TVFPHSTT--TSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 1371 Query: 1319 PSGEVLETTAPGVEEISGLPS--GEVLETSTSAVGDLSGLPSGGEVLEISVSGVED--IS 1374 P+ TTA EE + PS G + A SGL +S S E + Sbjct: 1372 PA---TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP 1428 Query: 1375 GLPSGEVVETSASGIEDVSELPSG--EGLETSASGVEDLSRLPSGEEVLEISASGFGDLS 1432 G P+ + ++ P T++SGV + E S G + Sbjct: 1429 GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE-------ESSTSHSQPGSTHTT 1481 Query: 1433 GLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492 P T+ S++ + + S + E + S + + S+ GD + Sbjct: 1482 AFPDS-----TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 1536 Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPD----FSGLPSGFPTVSLV 1548 LP T+ SG ++ S ++ + S +GL + F PS T Sbjct: 1537 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1596 Query: 1549 DSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGS 1608 T V ST T + + L SE + +S +GT L S + Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT 1656 Query: 1609 PDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGT--SQ 1664 + GE P TS +SG TE + L S+ G+S E S Y + S Sbjct: 1657 SVLVGE--------------PTTSPISSGSTETTALPGSTTTAGLS-EKSTTFYSSPRSP 1701 Query: 1665 PFGITDLSGETSGVPDLSGQPSGLPG------FSGATSGVPDLVSGTTSGSGESSGITFV 1718 ++ S +SGV + S PG F G+T+ T S S S T + Sbjct: 1702 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL 1761 Query: 1719 D---TSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTS 1775 T+ + P + GS E + LP D + SG+++ S + S Sbjct: 1762 SPGSTTASSLGPESTTFHSSPGSTETTLLP----DNTTASGLLEASTPVHSSTGS----- 1812 Query: 1776 QTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAP 1835 P + P+G GES+ + S PS P++ + T S + P Sbjct: 1813 --PHTTLSPAGSTTRQGESTTFQ---SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTP 1867 Query: 1836 TAQ-EAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDF 1894 T A G E S +P + SGL+E S T Y S Sbjct: 1868 TTHFSASSTTLGRSEESTTVHSSPVATATTPS--PARSTTSGLVEES-----TAYHSSPG 1920 Query: 1895 ASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFE 1954 ++ T ESS A G S E S T TIS PP T + + E Sbjct: 1921 STQTMHFPESSTASGRSEE-----------SRTSHSSTTHTISS-----PPSTTSALVEE 1964 Query: 1955 SSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPD 2014 + S+ G S AT P S ES++ S+ G A + G Sbjct: 1965 PTSYHSSPG--STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 2022 Query: 2015 LSETTSAFHEANLERSSGL--GVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEA----- 2067 S +S E S G+S + TF S A +S STT+S V E+ Sbjct: 2023 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS 2082 Query: 2068 -PG------LPSATPTASGDR---TEISGDLSGHTSQLGVVISTSIPESEWTQQTQRP-- 2115 PG P +T T R T S S T+ L +TS P E T P Sbjct: 2083 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGS 2142 Query: 2116 AETHLEIESSSLLYSGEETHTVETATSPTDASI 2148 +T L S++ L G+E+ T ++ T ++ Sbjct: 2143 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2175 Score = 106 bits (264), Expect = 3e-22 Identities = 358/1575 (22%), Positives = 521/1575 (33%), Gaps = 219/1575 (13%) Query: 670 HAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAI 729 H F G + +P +E + +SP + T + PG TTA G Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHSSPGSTD----TTLSPG--------STTASSLGP---- 1773 Query: 730 LEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSP 789 E TT + E P T+ G+L P ST P T P+ S Sbjct: 1774 -ESTTFHSSPGSTETTLLPDNTTA-SGLLEASTPV----HSSTGSPHTTLSPAGSTTRQG 1827 Query: 790 SEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSA-----SEEPYT- 843 F S S P P VEL + PS P+ S+ SEE T Sbjct: 1828 ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887 Query: 844 -PSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDS- 901 SP + T P+ SG + S + S + + F ASG S Sbjct: 1888 HSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP---ESSTASGRSEESRTSH 1944 Query: 902 SGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGE 961 S T T+ S S L P + P S SG Sbjct: 1945 SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD---------------SSTTSGR 1989 Query: 962 VLETSASGVG-DLSGLPSGEVLETTAP--GVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018 E++AS D +G TT+ G S + SG + T PG GL Sbjct: 1990 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 2049 Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS---GEVLETTAPGVEDISGLPSGE 1075 ++P + P+ TT+ GV + S G T P GL Sbjct: 2050 TTFHSSPRSPATTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS 2105 Query: 1076 VLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA-APGVEDISGLPSGEVL 1134 ++PG D + LP+ T+ P E + S +TA +PG Sbjct: 2106 TTSHSSPGSTDTTLLPASTT--TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2163 Query: 1135 ETAAPGVEDISGLPSGEVLETAAPGVEDISGL---PSGEVLETAAPGVEDISGLPSGEVL 1191 ++PG + P T + G+ + S +G T +P GL Sbjct: 2164 FHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 2219 Query: 1192 ETAAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLE 1249 P + P TA VE+ + G T P SG + Sbjct: 2220 FQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 2275 Query: 1250 TAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETT 1308 ++P D SG PS T+ G S + G TT PG TT Sbjct: 2276 HSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG-------------STT 2319 Query: 1309 APGVDEISG-LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLS-----------GL 1356 PG+ E S S TT ++ L GE TS S G GL Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379 Query: 1357 PSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPS 1416 + S G + + P TS G E+ + S + ED + Sbjct: 2380 SEESTTVYSSSPGSTETTVFP--RTPTTSVRG-EEPTTFHSRPASTHTTLFTEDSTTSGL 2436 Query: 1417 GEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLP 1476 EE S +GLP+ + +++G + + PS +S S LS Sbjct: 2437 TEESTAFPGSPASTQTGLPA-----TLTTADLGEESTTFPS------SSGSTGTTLSPAR 2485 Query: 1477 SGKEDLVG-SASGDLDLGKLPSGTL-GSGQAPETSGLPSGFSGEYSGVDLGSGPP----S 1530 S LVG S L + TL GS P S + F D P S Sbjct: 2486 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 2545 Query: 1531 GLPDFSGL----PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586 G+ + S P T + DST T L T S G ++ L Sbjct: 2546 GVSEESSTSHSQPGSTHTTAFPDST--------TTPGLSRHSTTSHSSPGSTD---TTLL 2594 Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVS-GQPSG-FPDTSGETSGVTELSGL 1644 S SG + S + GS D + +S GQ S F + G T T L Sbjct: 2595 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTH--TTLFPD 2652 Query: 1645 SSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSG 1704 S+ GI ++ V T P T LS +S P L G+ + +T P S Sbjct: 2653 STTSSGIVEASTRVHSSTGSPR--TTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710 Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQF 1764 T+ ES TT+ G S + S KS + S Sbjct: 2711 ATAPVEES---------------TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 2755 Query: 1765 SGTVDSSGFTSQTPEFSGLPSGIAEVSGE-----SSRAEIGSSLPSGAYYGSGTPSSFPT 1819 SGT SS ++ + S I+ S E S G S S +Y S P S PT Sbjct: 2756 SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRS-PT 2812 Query: 1820 VSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLS-GLQSGLI 1878 +L ++ + + S +S A + P +S E + S G + Sbjct: 2813 TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV 2872 Query: 1879 EPS-------GEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEG- 1930 P GE P T + S ++ T + E S G + E++ P T + Sbjct: 2873 FPRSTTTSVRGEEP-TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT 2931 Query: 1931 VTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETS 1990 +T + +E P + + S + +T+G + +TP S + SS+ET+ Sbjct: 2932 LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP---------SRLSPSSTETT 2982 Query: 1991 AYPEAGFGASAAPEASREDSGSPDLSETTSAFH------EANLE--RSSGLGVSGSTLTF 2042 P + +P LSE ++ F+ +A L ++ GVS + T Sbjct: 2983 TLPGS--------------PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 3028 Query: 2043 QEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTS 2102 S +STTTS + E P+A+ ++ G S S LG +T Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQE----PTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084 Query: 2103 IPESEWTQQTQRPAETHLE--IESSSLLYSGE-ETHTVETATSPTDASIPAS----PEWK 2155 T+ T P +T +E+S+ +S HT T S T A + W Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 3144 Query: 2156 RESESTAAAPARSCA 2170 S++T + P + A Sbjct: 3145 SSSDTTPSPPGTTAA 3159 Score = 65.9 bits (159), Expect = 5e-10 Identities = 150/651 (23%), Positives = 230/651 (35%), Gaps = 62/651 (9%) Query: 1537 GLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLP 1596 G +G+ + +S +V V T + ++ G + + G+ D GRA G Sbjct: 79 GASAGWSVMFAGESVVVLVHLWMTGARVKNLGLVEFASPGD---------DGDGRAEGFS 129 Query: 1597 SGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGET------SGVTELSGLSSGQPG 1650 G LS QA + E SGF +G T T S SS P Sbjct: 130 LGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPF 189 Query: 1651 ISGEASGV----LYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706 + GV + G++ D S + + + SG PG +G T + Sbjct: 190 TTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSG-PGATGTTLFPSHSATSVF 248 Query: 1707 SGSGESSGITF--VDTSLVEVAPTTFKEEEGLGSVELSG------LPSGEADLSGKSGMV 1758 G ++S IT ++T+ + + TT E + S L SG S Sbjct: 249 VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKS 308 Query: 1759 DVSGQFSGTVDSSGFTSQT--PEFSGLPSGIAEVSGESSRA-EIGSSLPSGAYYGSGTPS 1815 S G + F T P S + + G + G++ PS S T Sbjct: 309 TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFH 368 Query: 1816 SFP----TVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGA--HSGAPDMSGEHSGFL 1868 S P T L D T + +A T + G P L S + H G P Sbjct: 369 SSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSK 428 Query: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL---PEVTLITS 1925 D S SG + T + S TT+ S SS +G S E++ + P T T Sbjct: 429 DTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA-SSTTLGHSEESTPVHSSPVATATTP 487 Query: 1926 EFVEGVTEPTISQELG-QRPP----VTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980 T + + R P H P+ +SG + G+T S Sbjct: 488 PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSS---TP 544 Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040 S + + TS + G S R+ S SE + A H + ++ + +GST Sbjct: 545 STTAALAHTSYHSSLG---STETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 601 Query: 2041 TFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI 2099 + G+++ +P SG TT+ G T PGL + T S S T+ L + Sbjct: 602 SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF------YSSPRSPDTTHLPASM 655 Query: 2100 STSIPESEWTQQTQRPAETHLEIESSSLLYSG--EETHTVETATSPTDASI 2148 ++S E T RP TH S G +E+ ++ PTD ++ Sbjct: 656 TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL 706 Score = 65.1 bits (157), Expect = 8e-10 Identities = 295/1322 (22%), Positives = 449/1322 (33%), Gaps = 215/1322 (16%) Query: 648 PGVRTVYLYPNQTGLP----DPLSRH------HAFCFRGISAVPSPGEEEGGTPTSPSGV 697 PG ++P T +P + H H F S EE P SP+ Sbjct: 3948 PGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 4007 Query: 698 EEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPG- 756 + T + + + EE+T PS + + + + TP SP Sbjct: 4008 Q----TGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE 4063 Query: 757 --ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814 LP P T + +E+ST ++ P A+ P+ + SEE S S S Sbjct: 4064 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH---- 4119 Query: 815 VELFPSEEPFP--SKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTG 872 FP S+EP+ S S T + P T S G++S S T Sbjct: 4120 TTAFPDSTTTSGLSQEPTTSHSSQGS----TEATLSPGSTTASSLGQQSTTFHSSPGDTE 4175 Query: 873 SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLT--STVGSGLPVES----GLPSGDEERI 926 + + SG + + +G L ++ LT S+ +GL ES PS + Sbjct: 4176 TTLLPDDTITSGLVEASTPTHSSTGSLHTT-LTPASSTSTGLQEESTTFQSWPSSSDTT- 4233 Query: 927 EWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTA 986 PS P+ +P +E S + S P+ T S G ++ Sbjct: 4234 --PSPPSTTAVP-----VEVSTTYHSRPSSTPT-----THFSASSTTLGRSEESTTVHSS 4281 Query: 987 PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGV 1046 PG +G L T + G P TT+P + SG T PG Sbjct: 4282 PGA-------TGTALFPTRSATSVLVGEP------TTSP-------ISSGSTETTALPGS 4321 Query: 1047 EDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVED---ISGLPSGEVLETAAPGV 1103 +GL ++P D + P+ TT+ GV + S G + TA P Sbjct: 4322 TTTAGLSEKSTTFYSSPRSPDTTLSPA----STTSSGVSEESTTSHSRPGSMHTTAFPSS 4377 Query: 1104 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1163 + G+ ++PG D T +PG S L ++PG + Sbjct: 4378 TTMPGVSQESTASHSSPGSTD----------TTLSPGSTTASSLGPESTTFHSSPGSTET 4427 Query: 1164 SGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1223 + LP T A G +LE + P V +G P T +P S Sbjct: 4428 TLLPD----NTTASG-----------LLEASTP-VHSSTGSPH----TTLSPAG---STT 4464 Query: 1224 PSGEVLETAA-PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS 1282 GE + P +D + P T + VE L T + G + Sbjct: 4465 RQGESTTFQSWPNSKDTTPAPP----TTTSAFVE----------LSTTSHGSPSSTPTTH 4510 Query: 1283 GEVLETTAPGVEEISGLPSGEVLETT--APGVDEISGLPSGEVLETTAPGVEEISGLPS- 1339 TT EE + + S V T +P SGL ++PG + P Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570 Query: 1340 ------GEVLETS-TSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV 1392 GE TS +S +S PS L + G T+ + D Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG-------STATTHFPD- 4622 Query: 1393 SELPSGEGLETSASGVEDLSRLPSGEEVLEISASG---FGDLSGLPSGGEGLETSASEVG 1449 S SG E++AS S+ +G VL ++ G+ + P +ET+A Sbjct: 4623 SSTTSGRSEESTAS---HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679 Query: 1450 TDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509 T GL +S S S S + + + T S TS Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739 Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTA--STASELEGR 1567 GL + +S GS P+ S S+ +++ ST S L Sbjct: 4740 GLVEESTAYHSSP--GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 4797 Query: 1568 GTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSG--EIPGLFGVSGQP 1625 T S G I+ ++ S SG +E S + SPD +G +P F SG+ Sbjct: 4798 PTSYHSSPGSIA---TTHFPESSTTSG---RSEESTASHSSPDTNGITPLPAHFTTSGRI 4851 Query: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685 + + ++ PG+S + S +LY +S+ T LS + +SG+P Sbjct: 4852 AESTTFYISPGSMETTLASTATTPGLSAK-STILYSSSRSPDQT-LSPASMTSSSISGEP 4909 Query: 1686 SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 + L + +T S TTSG + S TTF + G Sbjct: 4910 TSLYSQAESTHTTAFPASTTTSGLSQES--------------TTFHSKPG---------- 4945 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDS---SGFTSQTPEFSGLPSGIAEVS-------GESS 1795 S E LS S Q T S S ++ +P + +P G++E S G + Sbjct: 4946 STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVP-GLSEESTTFYSSPGSTE 5004 Query: 1796 RAEIGSSLPSGAYYGSGTPSSFP-----TVSLVDRTLVES-VTQAPTAQEAGEGPSGILE 1849 S + TP FP T +++ TL + + Q TA + +G Sbjct: 5005 TTAFSHSNTMSIHSQQSTP--FPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTP 5062 Query: 1850 LSGAHSGAPDMSGEHSGF-----------LDLSGLQSGLIEPSGEPPGTPYFSGDFASTT 1898 L A S A D+ GE + F S SGL E S +P F+ ST Sbjct: 5063 LP-ARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTE 5121 Query: 1899 NV 1900 ++ Sbjct: 5122 SL 5123 Score = 58.5 bits (140), Expect = 8e-08 Identities = 156/611 (25%), Positives = 225/611 (36%), Gaps = 101/611 (16%) Query: 1635 TSGVTELSGLSSGQPG----ISGEASGVLYGTSQPF-------GITD--LSGETSGVPDL 1681 +SGV+E S S +PG I+ S + G SQ G TD LS T+ L Sbjct: 301 SSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL 360 Query: 1682 SGQPSGL---PGFSGATSGVPDLVSGTTSGSGESSGITFVDTSL--VEVAPTTFKEEEGL 1736 + + PG++ T+ +PD + TTSG E+S T ++P++ EG Sbjct: 361 GPESTTFHSSPGYT-KTTRLPD--NTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGE 417 Query: 1737 GSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGL------------- 1783 + PS + SG + S T SS ++ T FS Sbjct: 418 PTT-FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 476 Query: 1784 ---PSGIAEVSGESSRAEIGSSLPSGAYY---GSGTPSSFPTVSLVDRTLVESVT-QAPT 1836 P A + A G S AY+ GS FP S ES T T Sbjct: 477 HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 536 Query: 1837 AQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFAS 1896 PS L+ + S E + F D S + SG E S +P D + Sbjct: 537 THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI-SGRSEESKASHSSP----DAMA 591 Query: 1897 TTNVSGES--SVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELG------QRPPVTH 1948 TT + S SV +G S S + ++ T+ T+P +S++ + P TH Sbjct: 592 TTVLPAGSTPSVLVGDS-TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTH 650 Query: 1949 TPQLFESSGKVSTAGDISGATP------VLPGS----GVEVSSVPESSS----ETSAYPE 1994 P SSG VS S + P PGS G+ S SS +T+ P Sbjct: 651 LPASMTSSG-VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPG 709 Query: 1995 AGFGASAAPE--------ASREDSGSPD------LSETTSAFHEANLERSSGLGVSGSTL 2040 + +S PE S E + PD L E + H + + L +GST Sbjct: 710 STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTT 769 Query: 2041 ------TFQEGEASAAPEVSGESTTTSDV--GTEAPGLPSATPTAS-GDRTEISGDLSGH 2091 TF +S + +TT++ V T + G PS+ PT R+ SG + Sbjct: 770 RQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEES 829 Query: 2092 TSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPAS 2151 T+ S P S T T E S+ +S THT+ +A S T A + Sbjct: 830 TTY------HSSPGSTQTMHFPESDTTSGRGEESTTSHSST-THTISSAPSTTSALVEEP 882 Query: 2152 PEWKRESESTA 2162 + STA Sbjct: 883 TSYHSSPGSTA 893 Score = 55.8 bits (133), Expect = 5e-07 Identities = 170/792 (21%), Positives = 243/792 (30%), Gaps = 83/792 (10%) Query: 690 TPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAIL--EFTTEPENQTEWEPAYT 747 T PS V+Q + P +TT P T + L E TT + E Sbjct: 4371 TTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 4430 Query: 748 PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP 807 P T+ G+L P ST P T P+ S F S S P P Sbjct: 4431 PDNTTA-SGLLEASTPV----HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 4485 Query: 808 SVRPFPSVELFPSEEPFPSKEPSPSEEPSA-----SEEPYT--PSPPVPSWTELPSSGEE 860 VEL + PS P+ S+ SEE T SP + T P+ Sbjct: 4486 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4545 Query: 861 SGAPDVSGDFTGS--GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918 SG + S + S + H S SG S S T T+ S S L Sbjct: 4546 SGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTS----HSSTTHTISSAPSTTSAL 4601 Query: 919 ---------PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASG 969 G +P + T + S G + LP+ G Sbjct: 4602 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV-LPARSTTSV-LLG 4659 Query: 970 VGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVED 1029 S + SG + T PG GL ++P + + TT E+ Sbjct: 4660 ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSAS---STTLGRSEE 4716 Query: 1030 ISGLPSGEVLETT--APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDI 1087 + + S V T +P SGL ++PG P +TA G + Sbjct: 4717 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE----SSTASGRSEE 4772 Query: 1088 SGLPSGEVLETAAPGVEDISGL---------PSGEVLETAAPGVEDISGLPSGEVLETAA 1138 S T + S L G + T P SG ++ Sbjct: 4773 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 4832 Query: 1139 PGVEDISGLP-----SGEVLETA----APGVEDISGLPSGEVLETAAPGVEDISGLPS-G 1188 P I+ LP SG + E+ +PG + + + +A S S Sbjct: 4833 PDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 4892 Query: 1189 EVLETAAPGVEDISGLPSG------EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1242 + L A+ ISG P+ TA P SGL + PG + + Sbjct: 4893 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLS 4952 Query: 1243 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSG 1302 P + A P G L T +P + GL ++PG E + Sbjct: 4953 PGSITTSSFAQEFTTPHSQP-GSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHS 5011 Query: 1303 EVL------ETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLET----STSAVGD 1352 + T P + L TT G E + S + T + S D Sbjct: 5012 NTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASD 5071 Query: 1353 LSGLP-----SGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASG 1407 L G P S SGL E T + S + S E LET A G Sbjct: 5072 LVGEPTTFYISPSPTYTTLFPASSSTSGLT--EESTTFHTSPSFTSTIVSTESLETLAPG 5129 Query: 1408 VEDLSRLPSGEE 1419 + ++ +G++ Sbjct: 5130 LCQEGQIWNGKQ 5141 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 118 bits (295), Expect = 8e-26 Identities = 325/1358 (23%), Positives = 452/1358 (33%), Gaps = 293/1358 (21%) Query: 681 PSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEE-ETTAVPSGETTAILEFTTEPENQ 739 P P ++G GV+ PG +P + P+G T ++ + E Sbjct: 222 PGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQY--KGEKG 279 Query: 740 TEWEPAYTPVGTSPLPGI-----LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPF 794 +E EP + GI L +P G + E+ + G + + P P Sbjct: 280 SEGEPGIRGISLKGEEGIMGFPGLRGYP--GLSGEKGSPGQKGSRGLDGYQGPDGPRGP- 336 Query: 795 PSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTEL 854 E P P+ P PS+ +P P EP + EP P P P + Sbjct: 337 KGEAGDPGPPGLPAYSPHPSLAKGARGDP---GFPGAQGEPGSQGEPGDPGLPGPPGLSI 393 Query: 855 PSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGD---------RASGLPSGDLDSSGLT 905 + G P G GD + G D G P D GL Sbjct: 394 GDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLK 453 Query: 906 STVG-SGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEG-----SASGVGDLSGLPS 959 G +G P G P G W G E ++G G ++G P Sbjct: 454 GAKGRAGFPGLPGSP-GARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPG 512 Query: 960 -----GEVLETSASGVGDLSGLP-----------SGEVLETTAPGVEDISGLPS--GEVL 1001 G+ + G L G+P G+ T G G+P G Sbjct: 513 RKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKG 572 Query: 1002 ETTAPGVEDISGLP----------SGEVLETTAPGVEDISGLPSGEV--LETTAPGVEDI 1049 + +PG + + G P G + PG+ G P GE+ PG++ Sbjct: 573 DDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTP-GEMGPPGLGLPGLKGQ 631 Query: 1050 SGLPSGEVLETTAPGV----------------EDISGLPSGEVLETTAPGV----EDISG 1089 G P G+ PG D+ G+ E PG + + G Sbjct: 632 RGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPG 690 Query: 1090 LPSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVLETAA 1138 LP G T A G+ I G G+ PG G P G Sbjct: 691 LP-GPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIG-PRGSKGAVGL 748 Query: 1139 PGVEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1193 PG + G P G E PG ++ G G + PG + GLP + Sbjct: 749 PGPDGSPGPIGLPGPDGPPGERGLPG--EVLGAQPGPRGDAGVPGQPGLKGLPG----DR 802 Query: 1194 AAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETA 1251 PG G+P PG++ GL PSG+ PG+ G P G+ Sbjct: 803 GPPGFRGSQGMP-------GMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAP-GQEGPLG 854 Query: 1252 APGVEDISGLPS--GEVLETAAPGVEDISGLP--------SGEVLETTAPGVEEISGLPS 1301 PG+ GLP G+ +T APG + GL +GE +PG + I G+P Sbjct: 855 LPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPG 914 Query: 1302 GEVL--ETTAPGVDEISGLP-----------SGEVLETTAPGVEEISGLPSGEVLETSTS 1348 L + +PG+D G+P GE PG++ ++G P + Sbjct: 915 TPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFK------G 968 Query: 1349 AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGV 1408 + GD G P V+ + G++DI G E E P G A G+ Sbjct: 969 SRGD-PGPPGPPPVI---LPGMKDIKG--------------EKGDEGPMGLKGYLGAKGI 1010 Query: 1409 EDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASG 1468 + + +P SG L G P +G++ G + GLP G G+ +G Sbjct: 1011 QGMPGIP--------GLSGIPGLPGRPGHIKGVKGDIGVPG--IPGLP-GFPGV----AG 1055 Query: 1469 AEDLSGLPS-----------GKEDLVG--SASGDL-DLG---KLPSGTLGSGQAPETSGL 1511 ++G P G+ L G A+GD D+G LP G G T+G+ Sbjct: 1056 PPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLP-GRPGLKGERGTTGI 1114 Query: 1512 P--SGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569 P GF GE G+ G P +G+ L T +T S+ E G Sbjct: 1115 PGLKGFFGE-----KGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGE-LGR 1168 Query: 1570 IGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFP 1629 IG+ G G P A GLP G P + G I GL G+ G GFP Sbjct: 1169 IGLPGGKGDDGWPG--------APGLP----------GFPGLRG-IRGLHGLPG-TKGFP 1208 Query: 1630 DTSGETSGVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSGVPDLSGQPS- 1686 + G +++ G G PG GE G P G+ G+ G P G P Sbjct: 1209 GSPG-----SDIHG-DPGFPGPPGERGDPGEANTLPGPVGVPGQKGD-QGAPGERGPPGS 1261 Query: 1687 -GLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745 GL GF G T P +SG G AP F GL P Sbjct: 1262 PGLQGFPGITP--PSNISGAPGDKG---------------APGIF----GLKGYRGPPGP 1300 Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-----PEFSGLPSGIAEVSGESSRAEIG 1800 G A L G G G GT + G+ + P GLP E + +G Sbjct: 1301 PGSAALPGSKGDTGNPGA-PGTPGTKGWAGDSGPQGRPGVFGLP---GEKGPRGEQGFMG 1356 Query: 1801 SSLPSGAYYGSGTPS-----SFP-TVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAH 1854 ++ P+GA G FP V + + Q Q GP G Sbjct: 1357 NTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQG-------R 1409 Query: 1855 SGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSG 1892 G P GE + P G PPG P F G Sbjct: 1410 RGPPGAPGE--------------MGPQG-PPGEPGFRG 1432 Score = 96.3 bits (238), Expect = 3e-19 Identities = 238/1002 (23%), Positives = 336/1002 (33%), Gaps = 176/1002 (17%) Query: 750 GTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSV 809 G PG+ GA + +G S T + + E P P + + Sbjct: 524 GLPGFPGLKGVPGNIGAPGPKGAKGDSRT-ITTKGERGQPGVPGVPGMKGDDGSPGRDGL 582 Query: 810 RPFPSVELFPSEE-PFPSKEPSPSEEPSASEEPYTPSPP------------VPSWTELPS 856 FP + P + P +P P P PP P LP Sbjct: 583 DGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPG 642 Query: 857 SGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGL----------------PSGDLD 900 G P +G G + D + GDR + P G Sbjct: 643 PPGFLGPPGPAGT---PGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTG 699 Query: 901 SSGLTSTVG----SGLPVESGLPSGDEERIEWPSTPT-VGELPS-GAEILEGSASGVGDL 954 + GL G G P GLP GD R +P P +G S GA L G G + Sbjct: 700 AKGLRGIPGFAGADGGPGPRGLP-GDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPI 758 Query: 955 SGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL 1014 GLP + G++ G G + PG + GLP + PG G+ Sbjct: 759 -GLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPG----DRGPPGFRGSQGM 813 Query: 1015 PSGEVLETTAPGVEDISGLP--SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1072 P PG++ GLP SG+ PG+ G P G+ PG+ GLP Sbjct: 814 PG-------MPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAP-GQEGPLGLPGIPGREGLP 865 Query: 1073 S--GEVLETTAPGVEDISGLP--------SGEVLETAAPGVEDISGLPSGEVL--ETAAP 1120 G+ +T APG + GL +GE +PG + I G+P L + +P Sbjct: 866 GDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSP 925 Query: 1121 GVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVLE----------TAAPG 1159 G++ G+P GE PG++ ++G P + PG Sbjct: 926 GMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG 985 Query: 1160 VEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1214 ++DI G P G A G++ + G+P + PG+ G G + Sbjct: 986 MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPG----LSGIPGLPGRPGHIKGVKGDIGV 1041 Query: 1215 PGVEDISGLP--SGEVLETAAPGV---EDISGLPS-----GEVLETAAPG-VEDISGLPS 1263 PG+ + G P +G T PG G P GE+ T G + D LP Sbjct: 1042 PGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPG 1101 Query: 1264 -----GEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGL--PSGEVLETTAPGVDEIS 1316 GE T PG++ G G + PG+ ++G+ P G +T PG+ Sbjct: 1102 RPGLKGERGTTGIPGLKGFFG-EKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPP 1160 Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLE--TSTSAVGDLSGLPSGGEVLEISVSGVEDIS 1374 G GE+ PG + G P L + L GLP S + Sbjct: 1161 G-SQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDP 1219 Query: 1375 GLPSGEVVETSASGIEDVSELPSGEGL-----------ETSASGVEDLSRLPSGEEVLEI 1423 G P G E G + + LP G+ E G L P I Sbjct: 1220 GFP-GPPGERGDPG--EANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNI 1276 Query: 1424 S-------ASGFGDLSGL-----PSGGEGLETSASEVGTDLSGLPSGREGL--ETSASGA 1469 S A G L G P G L S + G + G +G ++ G Sbjct: 1277 SGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGR 1336 Query: 1470 EDLSGLPS-----GKEDLVGSASGDLDLG----KLPSGTLGSGQAPETSGLPSGFSG--E 1518 + GLP G++ +G+ +G K P G G AP T G P G +G + Sbjct: 1337 PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAP-GIAGIPQ 1395 Query: 1519 YSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT---IGISGA 1575 V G+ P G G P E+ E RG G G Sbjct: 1396 KIAVQPGTVGPQGRRGPPGAPG-------------EMGPQGPPGEPGFRGAPGKAGPQGR 1442 Query: 1576 GEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPG 1617 G +S +P D P G E + GSP + G +PG Sbjct: 1443 GGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPG-MPG 1483 Score = 37.0 bits (84), Expect = 0.24 Identities = 93/353 (26%), Positives = 117/353 (33%), Gaps = 52/353 (14%) Query: 1498 GTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--------GFPTVSLVD 1549 G G AP +G P G D+G+ SG P G+P G P + Sbjct: 88 GDKGERGAPGVTG-PKG--------DVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCN 138 Query: 1550 STLVEVVTASTASELEGRGTIGISGA----GEISGLPSSELDISGRASGLPSGTELSGQA 1605 T + G G G GE LP E D G P G Sbjct: 139 GTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPP 198 Query: 1606 SGSPDVSGEIPGLFGVSGQPS--GFPDTSGETS-------GVTELSGLSSGQPGISGEAS 1656 G P G++ G G G+P G P G+ GV G GQPG +G S Sbjct: 199 -GRPGHVGQM-GPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKG-DVGQPGPNGIPS 255 Query: 1657 GVLYGTSQPFGITDLSGETSGVPDLSGQP----------SGLPGFSGATSGVPDLVSGTT 1706 L+ P G+T + G G+P G+ GF G G P L SG Sbjct: 256 DTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPG-LRGYPGL-SG-E 312 Query: 1707 SGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSG 1766 GS G +D P K E G GLP+ S G G F G Sbjct: 313 KGSPGQKGSRGLDGYQGPDGPRGPKGE--AGDPGPPGLPAYSPHPSLAKGARGDPG-FPG 369 Query: 1767 TVDSSGFTSQTPEFSGLPS--GIAEVSGESSRAEIGSSLPSGAYYGSGTPSSF 1817 G + P GLP G++ G+ R G P G G P+ + Sbjct: 370 AQGEPGSQGE-PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALY 421 >gi|110624774 mannose receptor, C type 2 [Homo sapiens] Length = 1479 Score = 117 bits (292), Expect = 2e-25 Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%) Query: 2066 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2125 E G + T ++T I+G L+G++S L + ++ W P + +L ES Sbjct: 267 EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325 Query: 2126 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 2185 EE V S S W+ S A C ++P T + T Sbjct: 326 QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370 Query: 2186 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2245 PP N+ E CE W +QGHCYR ++ +W ++++ C L SI Sbjct: 371 -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421 Query: 2246 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2302 + E EF+ + + WIGLND ++ +F WSDG + F +W P +P+NF + EDC Sbjct: 422 SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481 Query: 2303 VVMIWHEKGEWNDVPCNYHLPFTCKK 2328 V IW +G WND PCN LP CKK Sbjct: 482 VT-IWGPEGRWNDSPCNQSLPSICKK 506 Score = 98.6 bits (244), Expect = 7e-20 Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%) Query: 2175 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 2227 G + +GH+ C Y + C I CE W+K Q CY+ +F +W Sbjct: 200 GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259 Query: 2228 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 2284 +A C +Q + L SI EQ ++N Y WIGLND G ++WSD P+++ Sbjct: 260 REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319 Query: 2285 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2336 NW +QPDN + E+C V+ G W + C+ LP+ CKK A EP Sbjct: 320 LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369 Score = 80.9 bits (198), Expect = 1e-14 Identities = 63/219 (28%), Positives = 97/219 (44%), Gaps = 25/219 (11%) Query: 2181 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 2240 +T+ IC P G T D W ++Q Y+ F TW A+R C Q+ Sbjct: 801 DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859 Query: 2241 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 2293 L+S+ + E +F+++N Q + WIGL+ +G FRW+DG + F +W P +P Sbjct: 860 LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919 Query: 2294 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTVAC-GEPPVVEHARTFGQKKD 2350 G+D CV M + +W D C LP+ CK+ V +PP + G D Sbjct: 920 ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSD 975 Query: 2351 RYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITC 2389 + + +C + VQ P R + W E Q +C Sbjct: 976 WIQFLN----KCFQ--VQGQEPQSRVK----WSEAQFSC 1004 Score = 65.5 bits (158), Expect = 6e-10 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 31/180 (17%) Query: 2180 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 2223 +E G CL Y + N+ +E C W ++ C++ Sbjct: 934 REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993 Query: 2224 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 2280 R W +A+ C +Q++ L +I P EQ F+ + + WIGL+ + DF+W + Sbjct: 994 RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051 Query: 2281 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 2330 P+ + NW P +P A C V++ H G W+D C F C+KGT Sbjct: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111 Score = 58.9 bits (141), Expect = 6e-08 Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%) Query: 2206 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2255 C +GW + +CY+ F D+++WV A+ C+E + L S+ + EE+ FV N Sbjct: 669 CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728 Query: 2256 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2303 + Q + WIGLN R G +RWSDG + N+ ++ D+ G C Sbjct: 729 KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786 Query: 2304 VMIWHEKGEWNDVPCNYHLPFTCK 2327 V+ +W + C+ L + CK Sbjct: 787 VLDLASL-QWVAMQCDTQLDWICK 809 Score = 58.5 bits (140), Expect = 8e-08 Identities = 48/194 (24%), Positives = 78/194 (40%), Gaps = 16/194 (8%) Query: 2206 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 2261 C +GW + CY D+ T+ +A R C + S L +I EQ FV+ N +Y Sbjct: 521 CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580 Query: 2262 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 2320 W L D G F W G + + +W +QP ++ G + G W C ++ Sbjct: 581 WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638 Query: 2321 HLPFTCKK--GTVACGEPPVVEHARTF-GQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQ 2377 + C++ GT E P + + G + ++ +RY C + F R Q Sbjct: 639 RARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQ 692 Query: 2378 PSGHWEEPQITCTD 2391 W + Q C + Sbjct: 693 DKKSWVQAQGACQE 706 Score = 50.8 bits (120), Expect = 2e-05 Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 9/145 (6%) Query: 2191 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 2249 PP H + Q + + W ++ HCY H +A +RC+ + SI+ E Sbjct: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310 Query: 2250 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2303 FV + Q Y+ W+G+N G W D + + NW P + C Sbjct: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369 Query: 2304 VMIWHEKGEWNDVPC-NYHLPFTCK 2327 I G W C N + CK Sbjct: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394 Score = 35.0 bits (79), Expect = 0.89 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 2227 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 2283 W DA C + + L+ + P Q F+ A+ + WIGL + W P+ Sbjct: 1146 WHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205 Query: 2284 FENWRPNQP 2292 + W+ +P Sbjct: 1206 YVGWQDGEP 1214 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 116 bits (291), Expect = 2e-25 Identities = 294/1158 (25%), Positives = 393/1158 (33%), Gaps = 249/1158 (21%) Query: 795 PSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPS----PSEEPSASEEPYTPSPPVPS 850 P + P P P+ P PS + P P P P P + + ++P PVP Sbjct: 490 PKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPG 549 Query: 851 WTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP--SGDLDSSGLTSTV 908 G P + GD + GH G L G++ G+P +G++ S G Sbjct: 550 EKGDQGLSGLMGPPGMQGD----KGLKGHPGLPG-LPGEQ--GIPGFAGNIGSPGYPGRQ 602 Query: 909 GSGLPVESGLPSGDEERIEWPSTPTVGEL-PSGAEILEG--SASGVGDLSGLPSGEVLET 965 G P + P G + I P G+L P G + G G G P G+ + Sbjct: 603 GLAGPEGNPGPKGAQGFIGSPGE--AGQLGPEGERGIPGIRGKKGFKGRQGFP-GDFGDR 659 Query: 966 SASGVGDLSGLPSGEVLETTAPGVEDISGL--PSGEVLETTAPGVEDISGLPSGEVLETT 1023 +G+ GL G T PG + G P G + PG +SG Sbjct: 660 GPAGLDGSPGLVGG----TGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSG-------NKG 708 Query: 1024 APGVEDISGLP--SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTA 1081 PG++ G +GE+ E PG + GLP PG+ SG PSG+ T Sbjct: 709 LPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPG-------PPGMRGKSG-PSGQ---TGD 757 Query: 1082 PGVEDISGLPSGEVL--ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--------G 1131 PG++ SG P E + PG G P G + PG + G G Sbjct: 758 PGLQGPSGPPGPEGFPGDIGIPGQNGPEG-PKGLLGNRGPPGPPGLKGTQGEEGPIGAFG 816 Query: 1132 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1191 E+ PG + +G P E L+ +I + GE PG ++G GE Sbjct: 817 ELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI--GETGPVGLPGEVGMTG-SIGEKG 873 Query: 1192 ETAAPGVEDISGLPSGEVLETAAPGVEDISG------LPSGEVLETAAPGVEDISGL--- 1242 E +PG P GE PG + G LP G V PG + G Sbjct: 874 ERGSPGPLG----PQGEKGVMGYPGPPGVPGPIGPLGLP-GHVGARGPPGSQGPKGQRGS 928 Query: 1243 --PSGEVLETAAPGVEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295 P G + E G + G P G + +T PG G P + L PG Sbjct: 929 RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL----PGSTG 984 Query: 1296 ISGLPSGEVLETTAPGVDEISGL--PSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDL 1353 GLP GE PG+ + G P GE+ PG E SG L+ A GD+ Sbjct: 985 DRGLP-GE------PGLRGLQGDVGPPGEMGMEGPPGTEGESG------LQGEPGAKGDV 1031 Query: 1354 SGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSR 1413 +G V T G+ P EGL+ Sbjct: 1032 G----------------------TAGSVGGTGEPGLRGEPGAPGEEGLQ----------- 1058 Query: 1414 LPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG-TDLSGL--PSGREGLETSASGAE 1470 G L G+P GG GL E G L G+ P GR G +T G E Sbjct: 1059 -------------GKDGLKGVP-GGRGLPGEDGEKGEMGLPGIIGPLGRSG-QTGLPGPE 1103 Query: 1471 DLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGL--PSGFSGEYSGV-DLGSG 1527 + G+P G+ G +G P+G +GS P G P G G V LG Sbjct: 1104 GIVGIP-GQRGRPGKKGDKGQIG--PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160 Query: 1528 PPSGLPDFSGL--PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSE 1585 P G P G G P G G+ G G P + Sbjct: 1161 GPDGEPGIPGYRGHQGQP------------------------GPSGLPGPKGEKGYPGED 1196 Query: 1586 LDISG----RASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGVT 1639 + G R P G + G+ G +PGL G +GQ G P G+ Sbjct: 1197 STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQ-QGPPGEPGD----- 1250 Query: 1640 ELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSG--QPSGLPGFSGATSG 1697 G+ G+ GE G G SG+ G+P L G P G+ G+ GA Sbjct: 1251 ------QGEQGLKGERGS--EGNKGKKGAPGPSGK-PGIPGLQGLLGPKGIQGYHGA--- 1298 Query: 1698 VPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGM 1757 D +SG G ++GL + G P G L+G G Sbjct: 1299 --DGISGNPGKIGPPG-------------------KQGLPGIR--GGP-GRTGLAGAPGP 1334 Query: 1758 VDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSF 1817 V G SG S G E GLP R G P G G P + Sbjct: 1335 PGVKGS-SGLPGSPGIQGPKGE-QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEY 1392 Query: 1818 PTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGL 1877 L Q + EG +GI+ +SG P H G G + G+ Sbjct: 1393 GVQGLTG-------FQGFPGPKGPEGDAGIVGISG-----PKGPIGHRGNTGPLG-REGI 1439 Query: 1878 IEPSGE--PPGTPYFSGD 1893 I P+G P G F G+ Sbjct: 1440 IGPTGRTGPRGEKGFRGE 1457 Score = 114 bits (285), Expect = 1e-24 Identities = 277/1053 (26%), Positives = 372/1053 (35%), Gaps = 190/1053 (18%) Query: 770 ESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRP-FPSVELFPSEEPFPSKE 828 E GP P P P+ +P PS + P P P P P + P P Sbjct: 485 EYLRGPKGDTGPPGP--PGPAGIPGPSGKRGPRGIPGPHGNPGLPGL-------PGPK-- 533 Query: 829 PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSG 888 P +P ++P PVP G P + GD + GH G L G Sbjct: 534 -GPKGDPG-----FSPGQPVPGEKGDQGLSGLMGPPGMQGD----KGLKGHPGLPG-LPG 582 Query: 889 DRASGLP--SGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGEL-PSGAEILE 945 ++ G+P +G++ S G G P + P G + I P G+L P G + Sbjct: 583 EQ--GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPG--EAGQLGPEGERGIP 638 Query: 946 G--SASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGL--PSGEVL 1001 G G G P G+ + +G+ GL G T PG + G P G + Sbjct: 639 GIRGKKGFKGRQGFP-GDFGDRGPAGLDGSPGLVGG----TGPPGFPGLRGSVGPVGPIG 693 Query: 1002 ETTAPGVEDIS---GLP-----------SGEVLETTAPGVEDISGLP--------SGEVL 1039 PG +S GLP +GE+ E PG + GLP SG Sbjct: 694 PAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSG 753 Query: 1040 ETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS----- 1092 +T PG++ SG P E + PG G P G + PG + G Sbjct: 754 QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEG-PKGLLGNRGPPGPPGLKGTQGEEGPI 812 Query: 1093 ---GEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS--------GLPSGEVLETAAPGV 1141 GE+ PG + +G P E L+ +I GLP GEV T + G Sbjct: 813 GAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLP-GEVGMTGSIGE 871 Query: 1142 EDISGL-----PSGEVLETAAPGVEDIS------GLPSGEVLETAAPGVEDISGL----- 1185 + G P GE PG + GLP G V PG + G Sbjct: 872 KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP-GHVGARGPPGSQGPKGQRGSRG 930 Query: 1186 PSGEVLETAAPGVEDISG-----LPSGEVLETAAPGVEDISGLPS-----GEVLETAAPG 1235 P G + E G + G P G + +T PG G P G + PG Sbjct: 931 PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG 990 Query: 1236 VEDISGL-----PSGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISG 1279 + GL P GE+ PG E SGL +G V T PG+ G Sbjct: 991 EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPG 1050 Query: 1280 LPSGEVLETTAPGVEEISGLPSGEVL-----ETTAPGVDEISGLPSGEVLETTAPGVEEI 1334 P E L+ G + + G+P G L E G+ I G P G +T PG E I Sbjct: 1051 APGEEGLQ----GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIG-PLGRSGQTGLPGPEGI 1105 Query: 1335 SGLPSGE---VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIED 1391 G+P + +G + S G +I SG + G G V G + Sbjct: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARG-TRGAVGHLGLMGPDG 1164 Query: 1392 VSELPS--GEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG 1449 +P G + SG+ P GE+ G+ G G VG Sbjct: 1165 EPGIPGYRGHQGQPGPSGLPG----PKGEK-------GYPGEDSTVLGPPGPRGEPGPVG 1213 Query: 1450 TDLSGLPSGREGLE--------TSASGAEDLSGLP--SGKEDLVGSASGDLDLGKLPS-G 1498 G EG + A+G + G P G++ L G + + GK + G Sbjct: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPG 1273 Query: 1499 TLGSGQAPETSGL--PSGFSGEYSGVDLGSGPPS--GLPDFSGLP---SGFPTVSLVDST 1551 G P GL P G G Y G D SG P G P GLP G L + Sbjct: 1274 PSGKPGIPGLQGLLGPKGIQG-YHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP 1332 Query: 1552 LVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDV 1611 V S+ G+ GI G GLP + I G+ G + G P + Sbjct: 1333 GPPGVKGSSGLP----GSPGIQGPKGEQGLP-GQPGIQGKRG--HRGAQGDQGPCGDPGL 1385 Query: 1612 SGEIPGLFGVSGQP--SGFPDTSGE--TSGVTELSGLSS--GQPGISGE--ASGVL--YG 1661 G+ PG +GV G GFP G +G+ +SG G G +G G++ G Sbjct: 1386 KGQ-PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTG 1444 Query: 1662 TSQPFGITDLSGETSGVPDLSGQPSGLPGFSGA 1694 + P G GET G GQP G PG GA Sbjct: 1445 RTGPRGEKGFRGET-GPQGPRGQP-GPPGPPGA 1475 Score = 56.6 bits (135), Expect = 3e-07 Identities = 151/567 (26%), Positives = 197/567 (34%), Gaps = 141/567 (24%) Query: 1427 GFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSA 1486 G L GLP G +G+ A +G+ G P GR+GL +G E G P G + +GS Sbjct: 573 GHPGLPGLP-GEQGIPGFAGNIGSP--GYP-GRQGL----AGPEGNPG-PKGAQGFIGSP 623 Query: 1487 SGDLDLGKLPSGTLGSGQAPETSGLPSGFSGE--YSGVDLGSGPPSGLPDFSGL-----P 1539 LG P G G P G GF G + G D G P+GL GL P Sbjct: 624 GEAGQLG--PEGERG---IPGIRG-KKGFKGRQGFPG-DFGDRGPAGLDGSPGLVGGTGP 676 Query: 1540 SGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGT 1599 GFP + RG++G G +G+P + +SG GLP Sbjct: 677 PGFPGL---------------------RGSVGPVGPIGPAGIPGP-MGLSGN-KGLPG-- 711 Query: 1600 ELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETS--GVTELSGLS--SGQPGISGEA 1655 + G G +GE+ G+P G+P G G + G S SGQ G G Sbjct: 712 -IKGD-KGEQGTAGEL-------GEP-GYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG-- 759 Query: 1656 SGVLYGTSQPFGITDLSGETSGVPDLSGQ--PSGLPGFSGATSGVPDLVSGTTSGSGESS 1713 L G S P G G+ G+P +G P GL G G P + GT G Sbjct: 760 ---LQGPSGPPGPEGFPGDI-GIPGQNGPEGPKGLLGNRGPPG--PPGLKGTQGEEGPIG 813 Query: 1714 GITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFS--GTVDSS 1771 G + G P G+ +G+ G + G+ G + Sbjct: 814 AF---------------------GELGPRGKP-GQKGYAGEPGPEGLKGEVGDQGNIGKI 851 Query: 1772 GFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSG--------AYYGS-GTPSSFPTVSL 1822 G T GLP + + E GS P G Y G G P + L Sbjct: 852 GETGPV----GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGL 907 Query: 1823 VDRTLVESV--TQAPTAQEAGEGPSGILELSG-----AHSGAPDMSGEHS---------- 1865 +Q P Q GP G+L G G G H Sbjct: 908 PGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967 Query: 1866 -GFLDLSGLQSGLIEPSGE-----PPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL-- 1917 GF GLQ GL +G+ PG GD + E GT GE SGL Sbjct: 968 RGFQGKPGLQ-GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEG--PPGTEGE-SGLQG 1023 Query: 1918 ---PEVTLITSEFVEGVTEPTISQELG 1941 + + T+ V G EP + E G Sbjct: 1024 EPGAKGDVGTAGSVGGTGEPGLRGEPG 1050 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.130 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 113,962,316 Number of Sequences: 37866 Number of extensions: 7109209 Number of successful extensions: 40897 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 398 Number of HSP's successfully gapped in prelim test: 1306 Number of HSP's that attempted gapping in prelim test: 22096 Number of HSP's gapped (non-prelim): 10963 length of query: 2416 length of database: 18,247,518 effective HSP length: 119 effective length of query: 2297 effective length of database: 13,741,464 effective search space: 31564142808 effective search space used: 31564142808 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.