Guide to the Human Genome
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Search of human proteins with 126090892

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
         (2416 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]             4852   0.0  
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]             4561   0.0  
gi|38372931 brevican isoform 2 [Homo sapiens]                         369   e-101
gi|38372935 brevican isoform 1 [Homo sapiens]                         369   e-101
gi|21361116 versican isoform 1 [Homo sapiens]                         363   1e-99
gi|187607300 versican isoform 2 [Homo sapiens]                        361   5e-99
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]        328   5e-89
gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sap...   224   6e-58
gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo sapi...   212   3e-54
gi|11141887 brain link protein-1 [Homo sapiens]                       189   2e-47
gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sap...   189   2e-47
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     149   4e-35
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    142   5e-33
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   142   5e-33
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   142   5e-33
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      133   2e-30
gi|167736355 mucin 4 isoform a [Homo sapiens]                         128   8e-29
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   127   1e-28
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   125   4e-28
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   125   4e-28
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   124   1e-27
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   124   1e-27
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   124   1e-27
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   124   1e-27
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   121   9e-27
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                       119   3e-26
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       119   5e-26
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]    118   8e-26
gi|110624774 mannose receptor, C type 2 [Homo sapiens]                117   2e-25
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              116   2e-25

>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 4852 bits (12586), Expect = 0.0
 Identities = 2416/2416 (100%), Positives = 2416/2416 (100%)

Query: 1    MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60
            MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV
Sbjct: 1    MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60

Query: 61   TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120
            TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV
Sbjct: 61   TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120

Query: 121  QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180
            QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA
Sbjct: 121  QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180

Query: 181  IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240
            IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE
Sbjct: 181  IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240

Query: 241  TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300
            TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG
Sbjct: 241  TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300

Query: 301  WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360
            WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN
Sbjct: 301  WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360

Query: 361  FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420
            FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF
Sbjct: 361  FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420

Query: 421  APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480
            APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF
Sbjct: 421  APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480

Query: 481  HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540
            HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS
Sbjct: 481  HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540

Query: 541  PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600
            PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES
Sbjct: 541  PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600

Query: 601  HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660
            HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT
Sbjct: 601  HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660

Query: 661  GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720
            GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA
Sbjct: 661  GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720

Query: 721  VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780
            VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV
Sbjct: 721  VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780

Query: 781  PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840
            PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE
Sbjct: 781  PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840

Query: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900
            PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD
Sbjct: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900

Query: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960
            SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG
Sbjct: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960

Query: 961  EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020
            EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL
Sbjct: 961  EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020

Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080
            ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
Sbjct: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080

Query: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140
            APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG
Sbjct: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140

Query: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200
            VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED
Sbjct: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200

Query: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260
            ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
Sbjct: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260

Query: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320
            LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS
Sbjct: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320

Query: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380
            GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE
Sbjct: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380

Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440
            VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG
Sbjct: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440

Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500
            LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL
Sbjct: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500

Query: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560
            GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST
Sbjct: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560

Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620
            ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG
Sbjct: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620

Query: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680
            VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD
Sbjct: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680

Query: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740
            LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE
Sbjct: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740

Query: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800
            LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG
Sbjct: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800

Query: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860
            SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM
Sbjct: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860

Query: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920
            SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV
Sbjct: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920

Query: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980
            TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS
Sbjct: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980

Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040
            SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL
Sbjct: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040

Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100
            TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS
Sbjct: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100

Query: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160
            TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES
Sbjct: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160

Query: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220
            TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH
Sbjct: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220

Query: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280
            FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH
Sbjct: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280

Query: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE 2340
            PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE
Sbjct: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVE 2340

Query: 2341 HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ 2400
            HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ
Sbjct: 2341 HARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQ 2400

Query: 2401 KRSSRHPRRSRPSTAH 2416
            KRSSRHPRRSRPSTAH
Sbjct: 2401 KRSSRHPRRSRPSTAH 2416


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 4561 bits (11831), Expect = 0.0
 Identities = 2292/2330 (98%), Positives = 2292/2330 (98%), Gaps = 38/2330 (1%)

Query: 1    MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60
            MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV
Sbjct: 1    MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPV 60

Query: 61   TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120
            TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV
Sbjct: 61   TTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEV 120

Query: 121  QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180
            QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA
Sbjct: 121  QSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSA 180

Query: 181  IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240
            IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE
Sbjct: 181  IIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNE 240

Query: 241  TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300
            TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG
Sbjct: 241  TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAG 300

Query: 301  WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360
            WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN
Sbjct: 301  WLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPEN 360

Query: 361  FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420
            FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF
Sbjct: 361  FFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTF 420

Query: 421  APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480
            APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF
Sbjct: 421  APEIGATAFAEVENETGEATRPWGFPTPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVF 480

Query: 481  HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540
            HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS
Sbjct: 481  HYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVS 540

Query: 541  PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600
            PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES
Sbjct: 541  PRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCES 600

Query: 601  HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660
            HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT
Sbjct: 601  HNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT 660

Query: 661  GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720
            GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA
Sbjct: 661  GLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTA 720

Query: 721  VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780
            VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV
Sbjct: 721  VPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEV 780

Query: 781  PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840
            PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE
Sbjct: 781  PSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEE 840

Query: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900
            PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD
Sbjct: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900

Query: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960
            SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG
Sbjct: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSG 960

Query: 961  EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020
            EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL
Sbjct: 961  EVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVL 1020

Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080
            ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
Sbjct: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080

Query: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140
            APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG
Sbjct: 1081 APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPG 1140

Query: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200
            VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED
Sbjct: 1141 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1200

Query: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260
            ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
Sbjct: 1201 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG 1260

Query: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320
            LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS
Sbjct: 1261 LPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPS 1320

Query: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380
            GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE
Sbjct: 1321 GEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGE 1380

Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440
            VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG
Sbjct: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440

Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500
            LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL
Sbjct: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500

Query: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560
            GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST
Sbjct: 1501 GSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTAST 1560

Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620
            ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG
Sbjct: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620

Query: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680
            VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD
Sbjct: 1621 VSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPD 1680

Query: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740
            LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE
Sbjct: 1681 LSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVE 1740

Query: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800
            LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG
Sbjct: 1741 LSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG 1800

Query: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860
            SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM
Sbjct: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDM 1860

Query: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920
            SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV
Sbjct: 1861 SGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEV 1920

Query: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980
            TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS
Sbjct: 1921 TLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980

Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040
            SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL
Sbjct: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040

Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100
            TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS
Sbjct: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVIS 2100

Query: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160
            TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES
Sbjct: 2101 TSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES 2160

Query: 2161 TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRH 2220
            TAA                                      DQEVCEEGWNKYQGHCYRH
Sbjct: 2161 TAA--------------------------------------DQEVCEEGWNKYQGHCYRH 2182

Query: 2221 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2280
            FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH
Sbjct: 2183 FPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGH 2242

Query: 2281 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT 2330
            PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT
Sbjct: 2243 PMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT 2292


>gi|38372931 brevican isoform 2 [Homo sapiens]
          Length = 671

 Score =  369 bits (946), Expect = e-101
 Identities = 205/435 (47%), Positives = 265/435 (60%), Gaps = 28/435 (6%)

Query: 23  SDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTTAPSTAPL--APRIKWSRVSK 80
           S  D +  V I   +PL+ +LG +LTIPC+    +H +   PS   +  +PR+KW+ +S+
Sbjct: 29  SSEDRAFRVRIAGDAPLQGVLGGALTIPCH----VHYLRPPPSRRAVLGSPRVKWTFLSR 84

Query: 81  EKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIE 140
            +E  +LVA   RV+VN AY+ +V+LP YPA  +D +L +  LR NDSG+YRCEV HGI+
Sbjct: 85  GREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGID 144

Query: 141 DSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCD 200
           DS   +EV VKG+VF YR  S RY   F  AQ AC +  A IATPEQL AAY  G+ QCD
Sbjct: 145 DSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCD 204

Query: 201 AGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATS 260
           AGWL+DQTVRYPI TPRE CYGD D FPGVR YG+ D ++ YDVYC+AE++ GE+F    
Sbjct: 205 AGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDP 264

Query: 261 PEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGG 320
           PEK T +EA   C+  GA +ATTGQLY AW  G+D CS GWLAD SVRYPI      CGG
Sbjct: 265 PEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGG 324

Query: 321 NLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD-IPE------NFFGVGGEEDITVQ 373
            L GV+T+++  NQTG+P+  SR++  C+        IPE      N    G E    + 
Sbjct: 325 GLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLE---AIV 381

Query: 374 TVTWPDMELPLPRNITEGEARGSVILTVKPIFE----VSPSPLEPEE------PFTFAPE 423
           TVT    EL LP+  TE E+RG++     PI E     S +P +P E       F     
Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSI--PIMEDGGGGSSTPEDPAEAPRTLLEFETQSM 439

Query: 424 IGATAFAEVENETGE 438
           +  T F+E E +  E
Sbjct: 440 VPPTGFSEEEGKALE 454



 Score =  291 bits (745), Expect = 5e-78
 Identities = 194/513 (37%), Positives = 250/513 (48%), Gaps = 56/513 (10%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF YR G  RY+ +F  AQ+AC R GA IA+PEQL AAY  GYEQCDAGWL DQTVRY
Sbjct: 156 GVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRY 215

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596
           PI +PR  C GD D  PGVR YGV    + YDVYC+ + L GE+F     E+ T +EA  
Sbjct: 216 PIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARA 275

Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656
           +C+   A +ATTGQLYAAW  GLD C  GWLADGS+RYPIVTP   CGG  PGV+T++L+
Sbjct: 276 YCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLF 335

Query: 657 PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPS--GVEEWI-VTQVVP------ 707
           PNQTG P+  SR + +CFR  SA PS   E     ++P+  G+E  + VT+ +       
Sbjct: 336 PNQTGFPNKHSRFNVYCFRD-SAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQ 394

Query: 708 ---------GVAAVPVEEE------TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752
                     + ++P+ E+      T   P+     +LEF T        +    P G S
Sbjct: 395 EATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFET--------QSMVPPTGFS 446

Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF---PSV 809
              G            EE  E     EV   +    PSE+  P  E S   EP     S+
Sbjct: 447 EEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESL 506

Query: 810 RPFPS-VELFPSEEPFPSKEPSPSEEPSASEEPY----TP------SPPVPSWTELPSSG 858
              P+   L P   P P  E   S  P     P     TP      SP   +  E    G
Sbjct: 507 SQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVG 566

Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQL-------SGDRASGLPSGDLDSSGLTSTVGSG 911
           E +G P++SG   G  + +G  + +  L        G R    PS   D+SG T+  G+ 
Sbjct: 567 EATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE--DNSGRTAPAGTS 624

Query: 912 LPVESGLPSGDEERIEWPSTPTVGELPSGAEIL 944
           +  +  LP+    R      P  G    G+  L
Sbjct: 625 VQAQPVLPTDSASRGGVAVVPASGNSAQGSTAL 657



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 33/184 (17%)

Query: 1572 ISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDT 1631
            +S  G  + LP+         S  P+   L   AS  PD   E      V G P+     
Sbjct: 486  LSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT----- 540

Query: 1632 SGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGF 1691
              ET        L+S  P    EA  V              GE +G P+LSG P G    
Sbjct: 541  --ETLPTPRERNLASPSPSTLVEAREV--------------GEATGGPELSGVPRGESEE 584

Query: 1692 SGATSGVPDLVSGTTSGSG---------ESSGITFVDTSLVE---VAPTTFKEEEGLGSV 1739
            +G++ G P L+  T +  G         ++SG T    + V+   V PT      G+  V
Sbjct: 585  TGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVV 644

Query: 1740 ELSG 1743
              SG
Sbjct: 645  PASG 648



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 42/133 (31%), Positives = 55/133 (41%), Gaps = 16/133 (12%)

Query: 1978 EVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDL----SETTSAFHEANLERSSGL 2033
            E ++  ES S+  A      GAS  P+   E S  P +    +ET     E NL   S  
Sbjct: 498  EPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSP- 556

Query: 2034 GVSGSTLTF--QEGEASAAPEVSGESTTTSDVGTEAPGLPS---ATPTASGDR--TEISG 2086
                STL    + GEA+  PE+SG     S+    + G PS   AT    G R     S 
Sbjct: 557  ----STLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE 612

Query: 2087 DLSGHTSQLGVVI 2099
            D SG T+  G  +
Sbjct: 613  DNSGRTAPAGTSV 625



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 17/155 (10%)

Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563
            QAP  + L  G S    G    S PP           G PT +L       + + S ++ 
Sbjct: 508  QAPARAVLQPGASPLPDGESEASRPPR--------VHGPPTETLPTPRERNLASPSPSTL 559

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASG-------SPDVSGE-I 1615
            +E R     +G  E+SG+P  E + +G + G PS    +    G       S D SG   
Sbjct: 560  VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTA 619

Query: 1616 PGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPG 1650
            P    V  QP   P  S    GV  +    +   G
Sbjct: 620  PAGTSVQAQPV-LPTDSASRGGVAVVPASGNSAQG 653



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 49/151 (32%), Positives = 67/151 (44%), Gaps = 25/151 (16%)

Query: 1097 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1156
            E ++PG E  + LP+    E AA   E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1157 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1212
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1213 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1241
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 25/151 (16%)

Query: 1059 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1118
            E ++PG E  + LP+    +      E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1119 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1174
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1175 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1203
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 11/114 (9%)

Query: 1371 EDISGLPSGEVVETSASGIEDVSELPS------GEGLETSASGVEDLSRLPSGEEVLEI- 1423
            E +S  P+  V++  AS + D     S      G   ET  +  E     PS   ++E  
Sbjct: 504  ESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAR 563

Query: 1424 ---SASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSG 1474
                A+G  +LSG+P G E  ET +SE    L       EG     + +ED SG
Sbjct: 564  EVGEATGGPELSGVPRG-ESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSG 616



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 28/162 (17%)

Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289
            E ++PG E  + LP+    E AA   E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1290 APGVE--EISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347
             P V       LP+       +P    +  + + EV E T  G  E+SG+P GE  ET +
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGEAT--GGPELSGVPRGESEETGS 587

Query: 1348 S----AVGDLSGLPSGGEVLEISVSGVEDISG--LPSGEVVE 1383
            S    ++   +  P G   LE   +  ED SG   P+G  V+
Sbjct: 588  SEGAPSLLPATRAPEGTRELE---APSEDNSGRTAPAGTSVQ 626



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 47/151 (31%), Positives = 66/151 (43%), Gaps = 25/151 (16%)

Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080
            E ++PG E  + LP+    +      E +S  P+  VL+   PG    S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQ---PGA---SPLPDGESEASR 531

Query: 1081 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1136
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1137 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1165
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 50/181 (27%), Positives = 74/181 (40%), Gaps = 28/181 (15%)

Query: 1281 PSGEVLETTAPGVEE--ISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLP 1338
            P  E    T P  +E  +S  P+  VL+   PG    S LP GE   +  P V      P
Sbjct: 489  PGPEASLPTEPAAQEESLSQAPARAVLQ---PGA---SPLPDGESEASRPPRVHG----P 538

Query: 1339 SGEVLETSTS---AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSAS----GIED 1391
              E L T      A    S L    EV E   +G  ++SG+P GE  ET +S     +  
Sbjct: 539  PTETLPTPRERNLASPSPSTLVEAREVGE--ATGGPELSGVPRGESEETGSSEGAPSLLP 596

Query: 1392 VSELPSGEGLETSASGVEDLSR-LPSG-----EEVLEISASGFGDLSGLPSGGEGLETSA 1445
             +  P G   E  A   ++  R  P+G     + VL   ++  G ++ +P+ G   + S 
Sbjct: 597  ATRAPEGT-RELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGNSAQGST 655

Query: 1446 S 1446
            +
Sbjct: 656  A 656


>gi|38372935 brevican isoform 1 [Homo sapiens]
          Length = 911

 Score =  369 bits (946), Expect = e-101
 Identities = 205/435 (47%), Positives = 265/435 (60%), Gaps = 28/435 (6%)

Query: 23  SDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTTAPSTAPL--APRIKWSRVSK 80
           S  D +  V I   +PL+ +LG +LTIPC+    +H +   PS   +  +PR+KW+ +S+
Sbjct: 29  SSEDRAFRVRIAGDAPLQGVLGGALTIPCH----VHYLRPPPSRRAVLGSPRVKWTFLSR 84

Query: 81  EKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIE 140
            +E  +LVA   RV+VN AY+ +V+LP YPA  +D +L +  LR NDSG+YRCEV HGI+
Sbjct: 85  GREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGID 144

Query: 141 DSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCD 200
           DS   +EV VKG+VF YR  S RY   F  AQ AC +  A IATPEQL AAY  G+ QCD
Sbjct: 145 DSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCD 204

Query: 201 AGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATS 260
           AGWL+DQTVRYPI TPRE CYGD D FPGVR YG+ D ++ YDVYC+AE++ GE+F    
Sbjct: 205 AGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDP 264

Query: 261 PEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGG 320
           PEK T +EA   C+  GA +ATTGQLY AW  G+D CS GWLAD SVRYPI      CGG
Sbjct: 265 PEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGG 324

Query: 321 NLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD-IPE------NFFGVGGEEDITVQ 373
            L GV+T+++  NQTG+P+  SR++  C+        IPE      N    G E    + 
Sbjct: 325 GLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLE---AIV 381

Query: 374 TVTWPDMELPLPRNITEGEARGSVILTVKPIFE----VSPSPLEPEE------PFTFAPE 423
           TVT    EL LP+  TE E+RG++     PI E     S +P +P E       F     
Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSI--PIMEDGGGGSSTPEDPAEAPRTLLEFETQSM 439

Query: 424 IGATAFAEVENETGE 438
           +  T F+E E +  E
Sbjct: 440 VPPTGFSEEEGKALE 454



 Score =  325 bits (834), Expect = 3e-88
 Identities = 203/555 (36%), Positives = 276/555 (49%), Gaps = 52/555 (9%)

Query: 1894 FASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLF 1953
            F  +   S     +   S  AS   E  +  +E +E +  P  + E   R  +   P + 
Sbjct: 353  FRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIME 412

Query: 1954 ESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSA--------YPEAGFGASAAPEA 2005
            +  G  ST  D + A   L     +    P   SE           Y +         E 
Sbjct: 413  DGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEE 472

Query: 2006 SRED-----------SGSPDLS-ETTSAFHEANLERSSGLGV---SGSTLTFQEGEASAA 2050
              ED           S  P+ S  T  A  E +L ++    V     S L   E EAS  
Sbjct: 473  EVEDEALWAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRP 532

Query: 2051 PEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQ 2110
            P V G  T T     E   L S +P+   +  E+ G+ +G     GV       ESE T 
Sbjct: 533  PRVHGPPTETLPTPRER-NLASPSPSTLVEAREV-GEATGGPELSGVPRG----ESEETG 586

Query: 2111 QTQ---------RPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES- 2160
             ++         R  E   E+E+ S   SG         T+P   S+ A P    +S S 
Sbjct: 587  SSEGAPSLLPATRAPEGTRELEAPSEDNSGR--------TAPAGTSVQAQPVLPTDSASR 638

Query: 2161 --TAAAPARS-CAEEPC-GAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGH 2216
               A  PA   C   PC   GTC E E  V CLC PGY G+ C++    C  GW+ +QG 
Sbjct: 639  GGVAVVPASGDCVPSPCHNGGTCLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGA 698

Query: 2217 CYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRW 2276
            CY+HF  R +W +AE +CR   +HL+SI TPEEQ+F+NN  ++YQWIGLNDRTIEGDF W
Sbjct: 699  CYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLW 758

Query: 2277 SDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2336
            SDG P+ +ENW P QPD++F +GE+CVVM+WH++G+W+DVPCNYHL +TCK G V+CG P
Sbjct: 759  SDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPP 818

Query: 2337 PVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYK 2396
            P +  A+ FG+ + RYE+++++RY+C EG  QR++P IRCQ +G WE PQI+C  P    
Sbjct: 819  PELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPLIRCQENGRWEAPQISCV-PRRPA 877

Query: 2397 RRLQKRSSRHPRRSR 2411
            R L        R+ R
Sbjct: 878  RALHPEEDPEGRQGR 892



 Score =  290 bits (741), Expect = 2e-77
 Identities = 192/505 (38%), Positives = 248/505 (49%), Gaps = 56/505 (11%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF YR G  RY+ +F  AQ+AC R GA IA+PEQL AAY  GYEQCDAGWL DQTVRY
Sbjct: 156 GVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRY 215

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596
           PI +PR  C GD D  PGVR YGV    + YDVYC+ + L GE+F     E+ T +EA  
Sbjct: 216 PIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARA 275

Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656
           +C+   A +ATTGQLYAAW  GLD C  GWLADGS+RYPIVTP   CGG  PGV+T++L+
Sbjct: 276 YCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLF 335

Query: 657 PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPS--GVEEWI-VTQVVP------ 707
           PNQTG P+  SR + +CFR  SA PS   E     ++P+  G+E  + VT+ +       
Sbjct: 336 PNQTGFPNKHSRFNVYCFRD-SAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQ 394

Query: 708 ---------GVAAVPVEEE------TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752
                     + ++P+ E+      T   P+     +LEF T        +    P G S
Sbjct: 395 EATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFET--------QSMVPPTGFS 446

Query: 753 PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPF---PSV 809
              G            EE  E     EV   +    PSE+  P  E S   EP     S+
Sbjct: 447 EEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESL 506

Query: 810 RPFPS-VELFPSEEPFPSKEPSPSEEPSASEEPY----TP------SPPVPSWTELPSSG 858
              P+   L P   P P  E   S  P     P     TP      SP   +  E    G
Sbjct: 507 SQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVG 566

Query: 859 EESGAPDVSGDFTGSGDVSGHLDFSGQL-------SGDRASGLPSGDLDSSGLTSTVGSG 911
           E +G P++SG   G  + +G  + +  L        G R    PS   D+SG T+  G+ 
Sbjct: 567 EATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSE--DNSGRTAPAGTS 624

Query: 912 LPVESGLPSGDEERIEWPSTPTVGE 936
           +  +  LP+    R      P  G+
Sbjct: 625 VQAQPVLPTDSASRGGVAVVPASGD 649



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 33/184 (17%)

Query: 1572 ISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDT 1631
            +S  G  + LP+         S  P+   L   AS  PD   E      V G P+     
Sbjct: 486  LSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPT----- 540

Query: 1632 SGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGF 1691
              ET        L+S  P    EA  V              GE +G P+LSG P G    
Sbjct: 541  --ETLPTPRERNLASPSPSTLVEAREV--------------GEATGGPELSGVPRGESEE 584

Query: 1692 SGATSGVPDLVSGTTSGSG---------ESSGITFVDTSLVE---VAPTTFKEEEGLGSV 1739
            +G++ G P L+  T +  G         ++SG T    + V+   V PT      G+  V
Sbjct: 585  TGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVV 644

Query: 1740 ELSG 1743
              SG
Sbjct: 645  PASG 648



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 40/143 (27%), Positives = 54/143 (37%), Gaps = 17/143 (11%)

Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563
            QAP  + L  G S    G    S PP           G PT +L       + + S ++ 
Sbjct: 508  QAPARAVLQPGASPLPDGESEASRPPR--------VHGPPTETLPTPRERNLASPSPSTL 559

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASG-------SPDVSGE-I 1615
            +E R     +G  E+SG+P  E + +G + G PS    +    G       S D SG   
Sbjct: 560  VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTA 619

Query: 1616 PGLFGVSGQPSGFPDTSGETSGV 1638
            P    V  QP   P  S    GV
Sbjct: 620  PAGTSVQAQPV-LPTDSASRGGV 641



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 28/187 (14%)

Query: 1281 PSGEVLETTAPGVEE--ISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLP 1338
            P  E    T P  +E  +S  P+  VL+   PG    S LP GE   +  P V      P
Sbjct: 489  PGPEASLPTEPAAQEESLSQAPARAVLQ---PGA---SPLPDGESEASRPPRVHG----P 538

Query: 1339 SGEVLETSTS---AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSAS----GIED 1391
              E L T      A    S L    EV E   +G  ++SG+P GE  ET +S     +  
Sbjct: 539  PTETLPTPRERNLASPSPSTLVEAREVGE--ATGGPELSGVPRGESEETGSSEGAPSLLP 596

Query: 1392 VSELPSGEGLETSASGVEDLSR-LPSG-----EEVLEISASGFGDLSGLPSGGEGLETSA 1445
             +  P G   E  A   ++  R  P+G     + VL   ++  G ++ +P+ G+ + +  
Sbjct: 597  ATRAPEGT-RELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPC 655

Query: 1446 SEVGTDL 1452
               GT L
Sbjct: 656  HNGGTCL 662



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 49/151 (32%), Positives = 67/151 (44%), Gaps = 25/151 (16%)

Query: 1097 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1156
            E ++PG E  + LP+    E AA   E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1157 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1212
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1213 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1241
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 46/151 (30%), Positives = 65/151 (43%), Gaps = 25/151 (16%)

Query: 1059 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA 1118
            E ++PG E  + LP+    +      E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1119 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1174
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1175 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1203
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616



 Score = 32.0 bits (71), Expect = 7.6
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 11/114 (9%)

Query: 1371 EDISGLPSGEVVETSASGIEDVSELPS------GEGLETSASGVEDLSRLPSGEEVLEI- 1423
            E +S  P+  V++  AS + D     S      G   ET  +  E     PS   ++E  
Sbjct: 504  ESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAR 563

Query: 1424 ---SASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSG 1474
                A+G  +LSG+P G E  ET +SE    L       EG     + +ED SG
Sbjct: 564  EVGEATGGPELSGVPRG-ESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSG 616



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 28/162 (17%)

Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289
            E ++PG E  + LP+    E AA   E +S  P+  VL+  A      S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPT----EPAAQE-ESLSQAPARAVLQPGA------SPLPDGESEASR 531

Query: 1290 APGVE--EISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347
             P V       LP+       +P    +  + + EV E T  G  E+SG+P GE  ET +
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGEAT--GGPELSGVPRGESEETGS 587

Query: 1348 S----AVGDLSGLPSGGEVLEISVSGVEDISG--LPSGEVVE 1383
            S    ++   +  P G   LE   +  ED SG   P+G  V+
Sbjct: 588  SEGAPSLLPATRAPEGTRELE---APSEDNSGRTAPAGTSVQ 626



 Score = 31.6 bits (70), Expect = 9.9
 Identities = 47/151 (31%), Positives = 66/151 (43%), Gaps = 25/151 (16%)

Query: 1021 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT 1080
            E ++PG E  + LP+    +      E +S  P+  VL+   PG    S LP GE   + 
Sbjct: 485  ELSSPGPE--ASLPTEPAAQE-----ESLSQAPARAVLQ---PGA---SPLPDGESEASR 531

Query: 1081 APGVED--ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET-- 1136
             P V       LP+      A+P    +  + + EV E  A G  ++SG+P GE  ET  
Sbjct: 532  PPRVHGPPTETLPTPRERNLASPSPSTL--VEAREVGE--ATGGPELSGVPRGESEETGS 587

Query: 1137 --AAPGVEDISGLPSGEVLETAAPGVEDISG 1165
               AP +   +  P G   E  AP  ED SG
Sbjct: 588  SEGAPSLLPATRAPEG-TRELEAPS-EDNSG 616


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score =  363 bits (932), Expect = 1e-99
 Identities = 346/1212 (28%), Positives = 539/1212 (44%), Gaps = 172/1212 (14%)

Query: 3    TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62
            ++LW+  TL ++T A+            V + +  P+R  L   +++PC+F   M  +  
Sbjct: 7    SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54

Query: 63   APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116
            + +T+    RIKWS++  +K      E  +LVA  G +++   Y+ +VS+P +P    DA
Sbjct: 55   SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113

Query: 117  TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176
            +L V  L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL
Sbjct: 114  SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173

Query: 177  QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236
               A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI  PR GCYGDK    GVRTYG R
Sbjct: 174  DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233

Query: 237  DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296
               ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC    ARLAT G+L  AW+ G D 
Sbjct: 234  SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293

Query: 297  CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD 356
            C  GWL+D SVR+P++ AR  CGG LLGVRT+Y   NQTG+P P SR+DA C+  ++   
Sbjct: 294  CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATT 353

Query: 357  IPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEP-- 414
            I           D+++   T        P+ +++   R + I+ +     V P+   P  
Sbjct: 354  I-----------DLSILAETASPSLSKEPQMVSD---RTTPIIPLVDELPVIPTEFPPVG 399

Query: 415  -----EEPFTFAPEIGATAFA-EVENETGEATRPW---GFPTPGLGPATAFTSEDLVVQV 465
                 E+  T  P+    + A ++   TG   +PW    +     GP       ++  +V
Sbjct: 400  NIVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEV 459

Query: 466  -TAVPGQPHLP----GGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAG 520
              +  G  H       GVV       T+ S+T    Q   +  G ++ S E L+      
Sbjct: 460  LQSTTGVSHYATDSWDGVV---EDKQTQESVT----QIEQIEVGPLVTSMEILKHIPSKE 512

Query: 521  YEQCD-----AGWLRDQTVRYPIVSPRTPCV---------GDKDSSPGVRTYGVRPSTET 566
            +   +     A  + +      +VS  +  V         G++D      T G   ST  
Sbjct: 513  FPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLI 572

Query: 567  YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATT--------GQLYAAWSRG 618
            +D          EV   ++  + T    LE  ES +A+   +        G     W   
Sbjct: 573  FDQI-------PEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWE-- 623

Query: 619  LDKCYAGWLADGSL-RYPIVTPRPA----------CGGDK---PGVRTVYLYPN-QTGLP 663
             ++  +G + +  L +Y   TP P+            GDK    G+ TV +YP+ QT + 
Sbjct: 624  -ERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTV-IYPSLQTEMT 681

Query: 664  DPLSRHHAFC--FRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAV 721
                R        R  +      EE   +P      EE      +    + P+    ++V
Sbjct: 682  HRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSV 741

Query: 722  PSGET----TAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSA 777
               ++    T I + + EP    + E  +T       PG   T       T     G  +
Sbjct: 742  EMTKSFDFPTLITKLSAEPTEVRDMEEDFTAT-----PG--TTKYDENITTVLLAHGTLS 794

Query: 778  TEVPSAS----EEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSE 833
             E  + S    +E + +  P  S EPS S +  P++    +V +   ++  PS     ++
Sbjct: 795  VEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPAL--LTTVGMNGKDKDIPSFTEDGAD 852

Query: 834  EPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASG 893
            E                +T +P S ++    +V+ +     D++ H  F+ +     ++G
Sbjct: 853  E----------------FTLIPDSTQKQ-LEEVTDE-----DIAAHGKFTIRFQPTTSTG 890

Query: 894  LPSGDL--DSS------GLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILE 945
            +       DS+       +TST G       G   G+ E ++   +  V  +P  A   E
Sbjct: 891  IAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVD--LSKPVSTVPQFAHTSE 948

Query: 946  GSASGVGDLSGLPSGE-VLETSASGVGDLSGLPSGE--VLETTAPGVEDISGLPSGEVL- 1001
                G+  +S   + E      +S    LS +P  +  VL  + P  +++ G PS ++L 
Sbjct: 949  --VEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILV 1006

Query: 1002 -------ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL-- 1052
                    T +P     + +  G   E   P  E  +  P   +  T     E ++ L  
Sbjct: 1007 IDQTRLEATISPETMRTTKITEGTTQE-EFPWKEQTAEKPVPALSSTAWTPKEAVTPLDE 1065

Query: 1053 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-GLPSGEVLETAAPGVEDISGLPS 1111
              G+    T    E ++G     VLETT  G  D S   P G V E      E ++  P 
Sbjct: 1066 QEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR 1125

Query: 1112 GEVLETAAPGVE 1123
                 + +PG E
Sbjct: 1126 IGPKVSLSPGPE 1137



 Score =  333 bits (853), Expect = 2e-90
 Identities = 195/484 (40%), Positives = 251/484 (51%), Gaps = 52/484 (10%)

Query: 1919 EVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVE 1978
            E T I  +F +  T+  +S E  +  P   TP+    +G V T  D            +E
Sbjct: 2924 EGTEILQDF-QNKTDGQVSGEAIKMFPTIKTPE----AGTVITTAD-----------EIE 2967

Query: 1979 VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGS 2038
            +    +    TSA    G  A   P  S + S  P LS +     E N E  + L + G 
Sbjct: 2968 LEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSP----EINPETQAAL-IRGQ 3022

Query: 2039 TLTFQEGEASAAPEV--SGESTTTSDV--GTEAPGLPSATPTASGDRTEISGDLSGHTSQ 2094
              T    E   A  +  S +  T + V   TE    P +    S +   + G      S 
Sbjct: 3023 DSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIG--INEESV 3080

Query: 2095 LGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEW 2154
             G  I    P+                 + +  L  G       T TS     +P     
Sbjct: 3081 EGTAIYLPGPD---------------RCKMNPCLNGGT---CYPTETSYVCTCVPGY--- 3119

Query: 2155 KRESESTAAAPARSCAEEPCGAG-TCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKY 2213
               S          C   PC  G TC +      CLC P Y G  C  D E C+ GW+K+
Sbjct: 3120 ---SGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKF 3176

Query: 2214 QGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGD 2273
            QG CY++F  R TW  AER CR Q +HL+SI++ EEQ FVN    DYQWIGLND+  E D
Sbjct: 3177 QGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHD 3236

Query: 2274 FRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVAC 2333
            FRW+DG  +Q+ENWRPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYHL +TCKKGTVAC
Sbjct: 3237 FRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVAC 3296

Query: 2334 GEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPT 2393
            G+PPVVE+A+TFG+ K RYEINSL+RY C +GF+QRH+PTIRC  +G W  P+ITC +P+
Sbjct: 3297 GQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPS 3356

Query: 2394 TYKR 2397
             Y+R
Sbjct: 3357 AYQR 3360



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 179/769 (23%), Positives = 269/769 (34%), Gaps = 105/769 (13%)

Query: 713  PVEEETTAVPSGETTAILEFTT--------EPENQTEWEPAYTPVGTSPLPGI------- 757
            P  EET  V       + EF            EN+ E E        +  P +       
Sbjct: 1356 PCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKH 1415

Query: 758  LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFP----SEEPSPSEEPFPSVRPFP 813
            L T  P      E+  G   +  PS +   S      P      E S + +P  S     
Sbjct: 1416 LVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTE 1475

Query: 814  SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873
            S+E+    E +P      SE  S  E    P+  VP   E  S   + GA  V+   T  
Sbjct: 1476 SLEVTWKPETYPET----SEHFSGGEPDVFPT--VPFHEEFESGTAKKGAESVTERDTEV 1529

Query: 874  GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933
            G  +        L  + +SG  + D +S      +      E       E+      TPT
Sbjct: 1530 GHQAHEHTEPVSLFPEESSGEIAIDQESQ----KIAFARATEVTFGEEVEKSTSVTYTPT 1585

Query: 934  VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993
            +  +PS A         V  +      ++L T  S V            E T   V ++S
Sbjct: 1586 I--VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV------------EATPRQVVELS 1631

Query: 994  GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053
            G  S  + E +    ED          +T    V D+S   + + L T      D S + 
Sbjct: 1632 GSSSIPITEGSGEAEEDE---------DTMFTMVTDLSQRNTTDTLITL-----DTSRII 1677

Query: 1054 SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG-LPSGEVLETAAPGVEDISGLPSG 1112
            +    E  A  +  +S  PS +V+ T      D S  + S  V E      E  +G  S 
Sbjct: 1678 TESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAST 1737

Query: 1113 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1172
              + ++    + +  LP     E  +P V   S   + +   +     +    +     +
Sbjct: 1738 FEVYSSTQRSDQLI-LP----FELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPV 1792

Query: 1173 ETAAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231
             T    +E++ G  + E      PGV++ ++ LP          G  + +  P    + +
Sbjct: 1793 FTETNTLENL-GAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS 1851

Query: 1232 AAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGV--EDISGLPSGEVLET 1288
             +  VE  +     EV  T +P VE   S  P+G VL T    V  E+I+   S E++ +
Sbjct: 1852 FSLNVE-YAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQT-SREIVIS 1909

Query: 1289 TAPGVE----EISGLPSGEVLETTAPG-VDEISGLPSGEVLETTAPGVEEISGLPSGEVL 1343
               G      EI G  +G  LE    G   E S +      E T   + E SG  +    
Sbjct: 1910 ERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETV--MMEGSGDAAFRDT 1967

Query: 1344 ETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGL 1401
            +TS S V              + +S + D  G PS  +V TSA   E+   S   SGE L
Sbjct: 1968 QTSPSTVPT-----------SVHISHISDSEG-PSSTMVSTSAFPWEEFTSSAEGSGEQL 2015

Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGT 1450
             T +S V  +  LPS  +    +AS   D        EGL     EVGT
Sbjct: 2016 VTVSSSVVPV--LPSAVQKFSGTASSIID--------EGL----GEVGT 2050



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 121/549 (22%), Positives = 188/549 (34%), Gaps = 117/549 (21%)

Query: 1614 EIPG--LFGVSGQPSGF---------PDTSGETSGVTELSGLSSGQPGISGEASGVLYGT 1662
            E+P   ++ VS QPS            DTS   S  T        + G +G AS     T
Sbjct: 1683 EVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAS-----T 1737

Query: 1663 SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGI-TFVDTS 1721
             + +  T  S +     +L          SG       L + T S    +     F +T+
Sbjct: 1738 FEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETN 1797

Query: 1722 LVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFS 1781
             +E       E     S+   G+  G   L      V +  Q SG   +   T+    FS
Sbjct: 1798 TLENLGAQTTEHS---SIHQPGVQEGLTTLPRSPASVFME-QGSGEAAADPETTTVSSFS 1853

Query: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841
                   E + ++ +   G+  P      S  P+     +++DR + E++TQ  T++E  
Sbjct: 1854 LN----VEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQ--TSREIV 1907

Query: 1842 EGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS 1901
                 I E  G  +   ++ G  +GF                 P    FSGDF   + VS
Sbjct: 1908 -----ISERLGEPNYGAEIRGFSTGF-----------------PLEEDFSGDFREYSTVS 1945

Query: 1902 G----ESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSG 1957
                 E +V M  SG+A+           F +  T P+        P   H   + +S G
Sbjct: 1946 HPIAKEETVMMEGSGDAA-----------FRDTQTSPSTV------PTSVHISHISDSEG 1988

Query: 1958 KVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSE 2017
              ST                           TSA+P   F +SA      E SG   ++ 
Sbjct: 1989 PSSTM------------------------VSTSAFPWEEFTSSA------EGSGEQLVTV 2018

Query: 2018 TTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTT--TSDV-GTEAPGLPSAT 2074
            ++S             G + S +    GE     E+   ST   T++V GT+AP      
Sbjct: 2019 SSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAP------ 2072

Query: 2075 PTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEET 2134
                 +  ++SG +S +  Q      T  P   W++Q   P    +E E++S     EE 
Sbjct: 2073 --VEKEEVKVSGTVSTNFPQ------TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEK 2124

Query: 2135 HTVETATSP 2143
                   SP
Sbjct: 2125 SFESPQNSP 2133


>gi|187607300 versican isoform 2 [Homo sapiens]
          Length = 655

 Score =  361 bits (926), Expect = 5e-99
 Identities = 177/357 (49%), Positives = 240/357 (67%), Gaps = 19/357 (5%)

Query: 3   TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62
           ++LW+  TL ++T A+            V + +  P+R  L   +++PC+F   M  +  
Sbjct: 7   SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54

Query: 63  APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116
           + +T+    RIKWS++  +K      E  +LVA  G +++   Y+ +VS+P +P    DA
Sbjct: 55  SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113

Query: 117 TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176
           +L V  L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL
Sbjct: 114 SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173

Query: 177 QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236
              A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI  PR GCYGDK    GVRTYG R
Sbjct: 174 DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233

Query: 237 DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296
              ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC    ARLAT G+L  AW+ G D 
Sbjct: 234 SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293

Query: 297 CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGED 353
           C  GWL+D SVR+P++ AR  CGG LLGVRT+Y   NQTG+P P SR+DA C+   D
Sbjct: 294 CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPD 350



 Score =  332 bits (851), Expect = 3e-90
 Identities = 142/230 (61%), Positives = 174/230 (75%), Gaps = 1/230 (0%)

Query: 2169 CAEEPCGAG-TCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETW 2227
            C   PC  G TC +      CLC P Y G  C  D E C+ GW+K+QG CY++F  R TW
Sbjct: 390  CHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTW 449

Query: 2228 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENW 2287
              AER CR Q +HL+SI++ EEQ FVN    DYQWIGLND+  E DFRW+DG  +Q+ENW
Sbjct: 450  DAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENW 509

Query: 2288 RPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQ 2347
            RPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYHL +TCKKGTVACG+PPVVE+A+TFG+
Sbjct: 510  RPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGK 569

Query: 2348 KKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKR 2397
             K RYEINSL+RY C +GF+QRH+PTIRC  +G W  P+ITC +P+ Y+R
Sbjct: 570  MKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR 619



 Score =  255 bits (652), Expect = 3e-67
 Identities = 120/199 (60%), Positives = 144/199 (72%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVFHYR   +RY+L FE AQ+ACL  GAVIA+PEQL AAYE G+EQCDAGWL DQTVRY
Sbjct: 149 GVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRY 208

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596
           PI +PR  C GDK    GVRTYG R   ETYDVYC+VD L+G+VF  T   +FTF+EA +
Sbjct: 209 PIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAK 268

Query: 597 FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656
            CE+ +A LAT G+L AAW  G D+C  GWL+D S+R+P+   R  CGG   GVRT+Y +
Sbjct: 269 ECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRF 328

Query: 657 PNQTGLPDPLSRHHAFCFR 675
            NQTG P P SR  A+CF+
Sbjct: 329 ENQTGFPPPDSRFDAYCFK 347


>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
          Length = 1321

 Score =  328 bits (840), Expect = 5e-89
 Identities = 161/315 (51%), Positives = 209/315 (66%), Gaps = 9/315 (2%)

Query: 39  LRVLLGTSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRV----SKEKEVVLLVATEGRV 94
           ++  L   + +PC F      +   PS A  APRIKW++V     + +++ +LVA +  V
Sbjct: 47  VQAALAELVALPCLFT-----LQPRPSAARDAPRIKWTKVRTASGQRQDLPILVAKDNVV 101

Query: 95  RVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIV 154
           RV  ++Q +VSLP+YP   ++ATL +  LR++DSG+YRC+V+ GIED +  + + V G+V
Sbjct: 102 RVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVV 161

Query: 155 FHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIH 214
           FHYR+   RY L F  AQ AC  +SAIIA P  LQAA+EDGF  CDAGWL+D+TVRYPI 
Sbjct: 162 FHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPIT 221

Query: 215 TPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECR 274
             R GCYGD+   PGVR+YG R+  E YDVYCFA E+ GEVFY     + T   A  +CR
Sbjct: 222 QSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCR 281

Query: 275 RLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQ 334
           R GA LA+ GQL+LAW  G+D C  GWLAD SVRYPI   R  CGG   GVRTVY  AN+
Sbjct: 282 RQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANR 341

Query: 335 TGYPDPSSRYDAICY 349
           TG+P P+ R+DA C+
Sbjct: 342 TGFPSPAERFDAYCF 356



 Score =  313 bits (802), Expect = 1e-84
 Identities = 210/636 (33%), Positives = 304/636 (47%), Gaps = 80/636 (12%)

Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850
            +GE+S A++       A + S +P  +P+V+   R +        TA E    P+G+  +
Sbjct: 708  TGETSPAQVNK-----AEHSSSSP--WPSVN---RNVAVGFVPTETATE----PTGLRGI 753

Query: 1851 SGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGT 1910
             G+ SG  D +   +     SGLQ+ + E   +P  + Y  G  AS+       S  +G+
Sbjct: 754  PGSESGVFDTAESPT-----SGLQATVDEVQ-DPWPSVYSKGLDASSP------SAPLGS 801

Query: 1911 SGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATP 1970
             G    +P+VT     +V     PT++         T TP   ++SG             
Sbjct: 802  PGVFL-VPKVTPNLEPWVATDEGPTVNPM-----DSTVTPAPSDASGIWE---------- 845

Query: 1971 VLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSP-------DLSETTSAFH 2023
              PGS      V E +  T+  P+     S     +  + G          L  ++S  H
Sbjct: 846  --PGS-----QVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSSQPH 898

Query: 2024 EANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGD--R 2081
                ++    G SG+++   +      P V   + T + VG E+  + S  PT   D   
Sbjct: 899  PEPEDQVETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVG-ESASVSSGEPTVPWDPSS 957

Query: 2082 TEISGDLSGHTSQLGVVISTSIPESEWTQQT--QRPAETHLEIESSSLLYSGEETHTVET 2139
            T +   L     +L V+  +   ES W +    + PA     +  + +    EE H+   
Sbjct: 958  TLLPVTLGIEDFELEVLAGSPGVESFWEEVASGEEPA-----LPGTPMNAGAEEVHSDPC 1012

Query: 2140 ATSP--------TDASIPASPEWKRESESTAAAPARSCAEEPC-GAGTCKETEGHVICLC 2190
              +P         + ++      +  +          C   PC   GTC +     +CLC
Sbjct: 1013 ENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLC 1072

Query: 2191 PPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQ 2250
             P Y G  C  D E C+ GW+K+QGHCYR+F  R  W DAE+ CR +  HL+S+ +PEE 
Sbjct: 1073 LPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEH 1132

Query: 2251 EFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEK 2310
             F+N+   +  WIGLNDR +E DF+W+D   +QFENWR NQPDNFFA GEDCVVM+ HE 
Sbjct: 1133 SFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHES 1192

Query: 2311 GEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRH 2370
            G WNDVPCNY+LP+ CKKGTV CG PP VE+A   G +K +Y +++ VRYQC EGF Q H
Sbjct: 1193 GRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHH 1252

Query: 2371 MPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRH 2406
            + TIRC+ +G W+ PQI CT P     R   R  RH
Sbjct: 1253 VATIRCRSNGKWDRPQIVCTKP-----RRSHRMRRH 1283



 Score =  262 bits (669), Expect = 3e-69
 Identities = 238/754 (31%), Positives = 321/754 (42%), Gaps = 94/754 (12%)

Query: 477  GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
            GVVFHYR    RY+LTF EAQ+AC  + A+IA+P  LQAA+E G++ CDAGWL D+TVRY
Sbjct: 159  GVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRY 218

Query: 537  PIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALE 596
            PI   R  C GD+ S PGVR+YG R   E YDVYCF   L GEVF+     + T   A  
Sbjct: 219  PITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARA 278

Query: 597  FCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLY 656
             C    A LA+ GQL+ AW  GLD+C  GWLADGS+RYPI TPR  CGG  PGVRTVY +
Sbjct: 279  QCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRF 338

Query: 657  PNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAV--PV 714
             N+TG P P  R  A+CFR       P  + G   T  SG E  I++   P V  +   +
Sbjct: 339  ANRTGFPSPAERFDAYCFR----AHHPTSQHGDLETPSSGDEGEILSAEGPPVRELEPTL 394

Query: 715  EEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEG 774
            EEE    P  +   +     E     E + +   +  +P   +L +W PTG     ST  
Sbjct: 395  EEEEVVTPDFQEPLVSSGEEETLILEEKQESQQTLSPTPGDPMLASW-PTGEVW-LSTVA 452

Query: 775  PSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFP--------S 826
            PS +++ + +   S +EV  P++        F  +    +   F  +EP P        S
Sbjct: 453  PSPSDMGAGTAASSHTEVA-PTDPMPRRRGRFKGL----NGRYFQQQEPEPGLQGGMEAS 507

Query: 827  KEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQL 886
             +P  SE      EP    P   + TE+  SG +S +P    D T   D+ G     G+ 
Sbjct: 508  AQPPTSEAAVNQMEP----PLAMAVTEMLGSG-QSRSP--WADLTNEVDMPGAGSAGGKS 560

Query: 887  SGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPS----TPTVGELPSGAE 942
            S +     P          + V   +   S  P  + E+ E PS    TP +   P  A 
Sbjct: 561  SPEPWLWPP----------TMVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLEAT 610

Query: 943  ILEGS-----ASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPS 997
            +   S     A  V     LP   +L      +     LP    + T A  VE       
Sbjct: 611  VSAPSPAPWEAFPVATSPDLPMMAMLRGPKEWM-----LPHPTPISTEANRVE-----AH 660

Query: 998  GEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLET--TAPGVEDISGLPSG 1055
            GE   T  P        P+ E    + P    +S  P+G+  E   T P         +G
Sbjct: 661  GEATATAPPS-------PAAETKVYSLP----LSLTPTGQGGEAMPTTPESPRADFRETG 709

Query: 1056 EVLETTAPGVEDISGLP---------SGEVLETTAPGVEDISGLPSGEVLETAAPGVEDI 1106
            E         E  S  P          G V   TA     + G+P  E       GV D 
Sbjct: 710  ETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGIPGSE------SGVFDT 763

Query: 1107 SGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1166
            +  P+   L+     V+D       + L+ ++P      G P   ++    P +E     
Sbjct: 764  AESPTSG-LQATVDEVQDPWPSVYSKGLDASSPSAP--LGSPGVFLVPKVTPNLEPWVAT 820

Query: 1167 PSGEVL----ETAAPGVEDISGL--PSGEVLETA 1194
              G  +     T  P   D SG+  P  +V E A
Sbjct: 821  DEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEA 854



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 99/407 (24%), Positives = 154/407 (37%), Gaps = 66/407 (16%)

Query: 654  YLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEG--GTPTSPSGVEEWIVTQVVPGVAA 711
            ++ P+ T +    +R  A      +A PSP  E      P S        +T    G  A
Sbjct: 642  WMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSLPLS--------LTPTGQGGEA 693

Query: 712  VPVEEETTAVP---SGETTAILEFTTEPENQTEWEPA-------YTPVGTSPLPGILPTW 761
            +P   E+       +GET+       E  + + W          + P  T+  P  L   
Sbjct: 694  MPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETATEPTGLRGI 753

Query: 762  PPTGAATEESTEGPSATEVPSASE--EPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFP 819
            P + +   ++ E P++    +  E  +P PS      +  SPS  P  S   F   ++ P
Sbjct: 754  PGSESGVFDTAESPTSGLQATVDEVQDPWPSVYSKGLDASSPSA-PLGSPGVFLVPKVTP 812

Query: 820  SEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGH 879
            + EP+ + +  P+  P  S     PS     W       EE+ +  +S        +   
Sbjct: 813  NLEPWVATDEGPTVNPMDSTVTPAPSDASGIWEPGSQVFEEAESTTLSPQVALDTSIVTP 872

Query: 880  LDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPS 939
            L    Q  GD+  G+P+         ST+GS        P   E+++E   T       S
Sbjct: 873  LTTLEQ--GDKV-GVPA--------MSTLGSSSSQPHPEP---EDQVETQGT-------S 911

Query: 940  GAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGE 999
            GA +    +S +G    +P G     +A+ VG+ + + SG   E T P        PS  
Sbjct: 912  GASVPPHQSSPLGK-PAVPPG---TPTAASVGESASVSSG---EPTVPWD------PSST 958

Query: 1000 VLETTAPGVEDISGLPSGEVLETTAPGVEDI-SGLPSGEVLETTAPG 1045
            +L  T  G+ED       EVL   +PGVE     + SGE  E   PG
Sbjct: 959  LLPVTL-GIEDF----ELEVL-AGSPGVESFWEEVASGE--EPALPG 997



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 154/730 (21%), Positives = 250/730 (34%), Gaps = 118/730 (16%)

Query: 1286 LETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEE---ISGLPSGEV 1342
            LET + G E       GE+L    P V E+   P+ E  E   P  +E    SG     +
Sbjct: 368  LETPSSGDE-------GEILSAEGPPVRELE--PTLEEEEVVTPDFQEPLVSSGEEETLI 418

Query: 1343 LETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLE 1402
            LE    +   LS  P           G   ++  P+GEV       +  V+  PS  G  
Sbjct: 419  LEEKQESQQTLSPTP-----------GDPMLASWPTGEV------WLSTVAPSPSDMGAG 461

Query: 1403 TSASG---VEDLSRLPSGEEVLE-ISASGFGDLSGLPSGGEGLETSA----SEVGTDLSG 1454
            T+AS    V     +P      + ++   F      P    G+E SA    SE   +   
Sbjct: 462  TAASSHTEVAPTDPMPRRRGRFKGLNGRYFQQQEPEPGLQGGMEASAQPPTSEAAVNQME 521

Query: 1455 LPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPET-----S 1509
             P      E   SG        S   DL    + ++D+    +G+ G   +PE      +
Sbjct: 522  PPLAMAVTEMLGSGQSR-----SPWADL----TNEVDMPG--AGSAGGKSSPEPWLWPPT 570

Query: 1510 GLPSGFSGEYSG----VDLGSGPPS--GLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563
             +P   SG        ++   GP +    PD    P    TVS       E    +T+ +
Sbjct: 571  MVPPSISGHSRAPVLELEKAEGPSARPATPDLFWSPLE-ATVSAPSPAPWEAFPVATSPD 629

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSG 1623
            L     +     G    +      IS  A+ + +  E +  A  SP    ++  L  +S 
Sbjct: 630  LPMMAML----RGPKEWMLPHPTPISTEANRVEAHGEATATAPPSPAAETKVYSL-PLSL 684

Query: 1624 QPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVP-DLS 1682
             P+G    +  T+  +  +           + +   + +S P+   + +     VP + +
Sbjct: 685  TPTGQGGEAMPTTPESPRADFRETGETSPAQVNKAEHSSSSPWPSVNRNVAVGFVPTETA 744

Query: 1683 GQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELS 1742
             +P+GL G  G+ SGV D     TSG                +  T  + ++   SV   
Sbjct: 745  TEPTGLRGIPGSESGVFDTAESPTSG----------------LQATVDEVQDPWPSVYSK 788

Query: 1743 GLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSS 1802
            GL +        S  V +  + +  ++    T + P  + + S +     ++S    G  
Sbjct: 789  GLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPAPSDAS----GIW 844

Query: 1803 LPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSG 1862
             P    +     ++      +D ++V  +T      + G      L   G+ S  P    
Sbjct: 845  EPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTL---GSSSSQPHPEP 901

Query: 1863 EHSGFLDLSGLQSGLIEP--------SGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEA 1914
            E    ++  G     + P           PPGTP  +    S +  SGE +V    S   
Sbjct: 902  EDQ--VETQGTSGASVPPHQSSPLGKPAVPPGTPTAASVGESASVSSGEPTVPWDPS--- 956

Query: 1915 SGLPEVTLITSEF----------VEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGD 1964
            S L  VTL   +F          VE   E   S   G+ P +  TP    ++G      D
Sbjct: 957  STLLPVTLGIEDFELEVLAGSPGVESFWEEVAS---GEEPALPGTPM---NAGAEEVHSD 1010

Query: 1965 ISGATPVLPG 1974
                 P L G
Sbjct: 1011 PCENNPCLHG 1020


>gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo
           sapiens]
          Length = 360

 Score =  224 bits (572), Expect = 6e-58
 Identities = 131/313 (41%), Positives = 178/313 (56%), Gaps = 25/313 (7%)

Query: 44  GTSLTIPCYFIDPMHPVTTAPSTAPLAPRIKWSRVSK----EKEVVLLVATEGRVRVNSA 99
           G S+ +PC +     P   +P       R+KW ++S+    EK+V  LVA   R R    
Sbjct: 63  GASVILPCRY--RYEPALVSPRRV----RVKWWKLSENGAPEKDV--LVAIGLRHRSFGD 114

Query: 100 YQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRA 159
           YQ +V L        D +LE+Q LR  D G YRCEV+ G+ED    +E+ ++G+VF Y++
Sbjct: 115 YQGRVHLRQDKE--HDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQS 172

Query: 160 ISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREG 219
            + RY  +F   Q+ C + +A++A+ EQL  A+E+G   C+AGWL D TV+YPI  PR+ 
Sbjct: 173 PNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQP 232

Query: 220 CYGDKDEFPGVRTYGIRDTN-ETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGA 278
           C G     PGVR+YG R      YDV+CFA  ++G V+Y   PEK T  EA   C+   A
Sbjct: 233 C-GGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDA 291

Query: 279 RLATTGQLYLAWQ-AGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGY 337
            +A  GQL+ AW+  G+D C AGWLAD SVRYP+    PNCG    GVR+        G+
Sbjct: 292 TIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF-------GF 344

Query: 338 PDPSSR-YDAICY 349
           PDP SR Y   CY
Sbjct: 345 PDPQSRLYGVYCY 357



 Score =  192 bits (489), Expect = 3e-48
 Identities = 100/202 (49%), Positives = 127/202 (62%), Gaps = 11/202 (5%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF Y+    RY   F E QQ C    AV+AS EQL  A+E G + C+AGWL+D TV+Y
Sbjct: 165 GVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQY 224

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVR-PSTETYDVYCFVDRLEGEVFFATRLEQFTFQEAL 595
           PI+ PR PC G    +PGVR+YG R      YDV+CF   L+G V++    E+ T  EA 
Sbjct: 225 PIMLPRQPC-GGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAR 283

Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654
           E C+  +AT+A  GQL+AAW   GLD+C AGWLADGS+RYP+V P P CG  +PGVR+  
Sbjct: 284 EACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF- 342

Query: 655 LYPNQTGLPDPLSR-HHAFCFR 675
                 G PDP SR +  +C+R
Sbjct: 343 ------GFPDPQSRLYGVYCYR 358


>gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo
           sapiens]
          Length = 354

 Score =  212 bits (540), Expect = 3e-54
 Identities = 129/343 (37%), Positives = 182/343 (53%), Gaps = 30/343 (8%)

Query: 22  TSDHDNSLSVSIPQPSPLRVLL---------GTSLTIPCYFI-DPMHPVTTAPSTAPLAP 71
           T DHD ++ +       L V           G ++T+PC F  DP     TA  +     
Sbjct: 23  TLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLPCKFYRDP-----TAFGSGIHKI 77

Query: 72  RIKWSRVSKE--KEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSG 129
           RIKW++++ +  KEV + V+     +    YQ +V L       SDA+L +  L   D G
Sbjct: 78  RIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKG--GSDSDASLVITDLTLEDYG 135

Query: 130 VYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQ 189
            Y+CEV+ G+ED    + + ++G+VF Y     RY L+F  AQ+ACL   A+IA+ +QL 
Sbjct: 136 RYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLY 195

Query: 190 AAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNET-YDVYCFA 248
            A+  G   C+AGWL+D +V+YPI  PRE C G ++  PGVR YG  D +++ YDV+CF 
Sbjct: 196 DAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFT 254

Query: 249 EEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQ-AGMDMCSAGWLADRSV 307
               G  +Y   P K T+ EA   C   GA++A  GQ++ AW+  G D C AGWLAD SV
Sbjct: 255 SNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSV 314

Query: 308 RYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICY 349
           RYPIS+ R  C      VR V       G+PD   + Y   C+
Sbjct: 315 RYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYCF 350



 Score =  169 bits (429), Expect = 2e-41
 Identities = 91/202 (45%), Positives = 120/202 (59%), Gaps = 11/202 (5%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF Y P   RY+L F EAQQACL   AVIAS +QL  A+  G + C+AGWL D +V+Y
Sbjct: 158 GVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQY 217

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRPSTET-YDVYCFVDRLEGEVFFATRLEQFTFQEAL 595
           PI  PR PC G +++ PGVR YG     ++ YDV+CF     G  ++     + T+ EA+
Sbjct: 218 PITKPREPC-GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAV 276

Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVY 654
           + C +  A +A  GQ++AAW   G D+C AGWLADGS+RYPI  PR  C   +  VR V 
Sbjct: 277 QACLNDGAQIAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV- 335

Query: 655 LYPNQTGLPDPLSR-HHAFCFR 675
                 G PD   + +  +CFR
Sbjct: 336 ------GFPDKKHKLYGVYCFR 351


>gi|11141887 brain link protein-1 [Homo sapiens]
          Length = 340

 Score =  189 bits (481), Expect = 2e-47
 Identities = 114/317 (35%), Positives = 169/317 (53%), Gaps = 30/317 (9%)

Query: 50  PCYFIDPMHPV--------TTAP---STAPLAPRIKWSRVS--KEKEVVLLVATEGRVRV 96
           P Y + P+H V         T P    T P + +++WS+V   + +E ++L+      R 
Sbjct: 34  PHYLLPPIHEVIHSHRGATATLPCVLGTTPPSYKVRWSKVEPGELRETLILITNGLHARG 93

Query: 97  NSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFH 156
                 +  +     +  DA+L +  +R  D G YRCE+++GIED    L + ++G+VF 
Sbjct: 94  YGPLGGRARMRRGHRL--DASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFP 151

Query: 157 YRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTP 216
           Y+    RY  ++  A++AC +    +AT  QL  A+ +G   C+AGWL + +VRYP+ T 
Sbjct: 152 YQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTA 211

Query: 217 REGCYGDKDEFPGVRTYGIRD-TNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRR 275
           R  C G     PG+R+YG RD   + YD +CF   + G+VF+   P + T  EA   CRR
Sbjct: 212 RAPCGGRGR--PGIRSYGPRDRMRDRYDAFCFTSALAGQVFFV--PGRLTLSEAHAACRR 267

Query: 276 LGARLATTGQLYLAWQ-AGMDMCSAGWLADRSVRYPISKARPNCGG-NLLGVRTVYVHAN 333
            GA +A  G LY AW+ +G+D C  GWLAD SVR+PI+  RP CGG    GVR+      
Sbjct: 268 RGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSF----- 322

Query: 334 QTGYPDP-SSRYDAICY 349
             G+P P  + Y   CY
Sbjct: 323 --GFPRPQQAAYGTYCY 337



 Score =  159 bits (401), Expect = 4e-38
 Identities = 83/179 (46%), Positives = 107/179 (59%), Gaps = 7/179 (3%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF Y+P   RY   + EA+QAC      +A+  QL  A+  G + C+AGWL + +VRY
Sbjct: 147 GVVFPYQPSRGRYQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRY 206

Query: 537 PIVSPRTPCVGDKDSSPGVRTYGVRP-STETYDVYCFVDRLEGEVFFATRLEQFTFQEAL 595
           P+++ R PC G     PG+R+YG R    + YD +CF   L G+VFF     + T  EA 
Sbjct: 207 PVLTARAPCGG--RGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFFVP--GRLTLSEAH 262

Query: 596 EFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGG-DKPGVRT 652
             C    A +A  G LYAAW   GLD+C  GWLADGS+R+PI TPRP CGG   PGVR+
Sbjct: 263 AACRRRGAVVAKVGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRS 321



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 42/88 (47%), Positives = 56/88 (63%), Gaps = 7/88 (7%)

Query: 588 QFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGG-D 646
           QF + EA + CE  +  LAT  QLY AW+ GLD C AGWL +GS+RYP++T R  CGG  
Sbjct: 160 QFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGGRG 219

Query: 647 KPGVRTVYLYPNQTGLPDPLSRHHAFCF 674
           +PG+R+   Y  +  + D   R+ AFCF
Sbjct: 220 RPGIRS---YGPRDRMRD---RYDAFCF 241


>gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo
           sapiens]
          Length = 402

 Score =  189 bits (481), Expect = 2e-47
 Identities = 112/307 (36%), Positives = 158/307 (51%), Gaps = 22/307 (7%)

Query: 72  RIKWSRVSKEKEVV-LLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGV 130
           R+KW++V        + VA   + R   +Y+ +  L      P DA+L ++++   D G 
Sbjct: 83  RLKWTKVVDPLAFTDVFVALGPQHRAFGSYRGRAELQGDG--PGDASLVLRNVTLQDYGR 140

Query: 131 YRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQA 190
           Y CEV + +ED    +++ ++G+VF Y     RY L F  AQRAC +   I+A+ EQL A
Sbjct: 141 YECEVTNELEDDAGMVKLDLEGVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHA 200

Query: 191 AYEDGFHQCDAGWLADQTVRYPIHTPREGC---------YGDKDEFPGVRTYGIR-DTNE 240
           A+ DG   C+AGWL D +V+YP++ PRE C          G  D   G+R YG R +  E
Sbjct: 201 AWRDGLDWCNAGWLRDGSVQYPVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEE 260

Query: 241 TYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAG-MDMCSA 299
            YD +CF   + G VF+        F  AA  C   GA +A  GQL+ AW+   +D C+A
Sbjct: 261 RYDAFCFTSNLPGRVFFLKPLRPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTA 320

Query: 300 GWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSR-YDAICYTGEDFVDIP 358
           GWLAD S RYPI   R  CGG   GVR++       G+PD + R +   CY      D  
Sbjct: 321 GWLADGSARYPIVNPRARCGGRRPGVRSL-------GFPDATRRLFGVYCYRAPGAPDPA 373

Query: 359 ENFFGVG 365
              +G G
Sbjct: 374 PGGWGWG 380



 Score =  185 bits (470), Expect = 4e-46
 Identities = 102/221 (46%), Positives = 127/221 (57%), Gaps = 20/221 (9%)

Query: 477 GVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRY 536
           GVVF Y P   RY LTF EAQ+AC     ++AS EQL AA+  G + C+AGWLRD +V+Y
Sbjct: 162 GVVFPYHPRGGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQY 221

Query: 537 PIVSPRTPC---------VGDKDSSPGVRTYGVRPST-ETYDVYCFVDRLEGEVFFATRL 586
           P+  PR PC          G  D++ G+R YG R +  E YD +CF   L G VFF   L
Sbjct: 222 PVNRPREPCGGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPL 281

Query: 587 EQFTFQEALEFCESHNATLATTGQLYAAWS-RGLDKCYAGWLADGSLRYPIVTPRPACGG 645
               F  A   C +  A +A  GQL+AAW  + LD+C AGWLADGS RYPIV PR  CGG
Sbjct: 282 RPVPFSGAARACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGG 341

Query: 646 DKPGVRTVYLYPNQTGLPDPLSR-HHAFCFRGISAV-PSPG 684
            +PGVR++       G PD   R    +C+R   A  P+PG
Sbjct: 342 RRPGVRSL-------GFPDATRRLFGVYCYRAPGAPDPAPG 375


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  149 bits (375), Expect = 4e-35
 Identities = 302/1164 (25%), Positives = 396/1164 (34%), Gaps = 197/1164 (16%)

Query: 753  PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSP----SEEPFPS 808
            P P   PT PP G   +     P    +P  + +P     P     P P       P   
Sbjct: 89   PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 809  VRPFPSVELFPSEE----------PFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSG 858
                P  + +  +           P P+  P P   P  S  P   SP  P +   P   
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHP--GSPGSPGYQGPPGEP 206

Query: 859  EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918
             ++G        +G     G +  SG    D  SG P               G P E GL
Sbjct: 207  GQAGP-------SGPPGPPGAIGPSGPAGKDGESGRP---------------GRPGERGL 244

Query: 919  PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPS 978
            P            P   + P+G     G   G     G  +GE  ET A G+   +GLP 
Sbjct: 245  PG-----------PPGIKGPAGIPGFPG-MKGHRGFDG-RNGEKGETGAPGLKGENGLPG 291

Query: 979  -----GEVLETTAPGVEDISGLPS-----------GEVLETTAPGVEDISGLP-----SG 1017
                 G +    APG     GLP            G   +   PG    +G P      G
Sbjct: 292  ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351

Query: 1018 EVLETTAPGVEDISGL-----PSGEVLETTAPGVEDISGLP--SGEVLETTAPGVEDISG 1070
            EV    +PG     G      P G       PG   I+G P   GE+     PG   + G
Sbjct: 352  EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMG 411

Query: 1071 L--PSGEVLETTAPGVEDISGLP-----SGEVLETAAPGVEDISGLP--SGEVLETAAPG 1121
               P G      APG+   +G P      GE       G   I G+P   GE  +  +PG
Sbjct: 412  ARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG 471

Query: 1122 VEDISGLPSGEVLETAAPGVE---DISGLP--SGEVLETAAPGVEDISGLPSGEVLETAA 1176
                +GLP G   E  APG       +G+P   G   E  APG     G  +GE      
Sbjct: 472  EPGANGLP-GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG-AAGEPGRDGV 529

Query: 1177 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1236
            PG   + G+P         PG +   G P G   E+  PG    SG P G+      PG 
Sbjct: 530  PGGPGMRGMPG----SPGGPGSDGKPG-PPGSQGESGRPGPPGPSG-PRGQPGVMGFPGP 583

Query: 1237 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEI 1296
            +   G P G+  E   PG     G P G+  ET   G    +G P G+  +T  PG + +
Sbjct: 584  KGNDGAP-GKNGERGGPGGPGPQG-PPGKNGETGPQGPPGPTG-PGGDKGDTGPPGPQGL 640

Query: 1297 SGLPS-----GEVLETTAPGVDEISGLPS--GEVLETTAPGVEEISGLPSGEVLETSTSA 1349
             GLP      GE  +   PG    +G P   G   +  APG     GL     L      
Sbjct: 641  QGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGP 700

Query: 1350 VGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGV- 1408
             G   G  + G       +G   + G+P GE     + G +     P G G    A GV 
Sbjct: 701  PGPEGGKGAAGPPGPPGAAGTPGLQGMP-GERGGLGSPGPKGDKGEPGGPG----ADGVP 755

Query: 1409 -EDLSRLPSGE-----EVLEISASGFGDLSGLP--SGGEGLETSASEVGTDLSGLPSGRE 1460
             +D  R P+G         +    G G   GLP  +G  G      E G      P G  
Sbjct: 756  GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG------PPGPA 809

Query: 1461 GLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLG--SGQAPETSGLPSGFSGE 1518
            G      GA   +G P GK +    A G+   G  P G  G   G  P     P G  GE
Sbjct: 810  GF----PGAPGQNGEPGGKGE--RGAPGEKGEGG-PPGVAGPPGGSGPAGPPGPQGVKGE 862

Query: 1519 YSGVDLGSGPPSGLPDFSGLP-----SGFPTVSLVDSTLVEVVTASTASELEGRGTIGIS 1573
                  G    +G P   GLP     +G P       +  +      A      G+ G+S
Sbjct: 863  RGSP--GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVS 920

Query: 1574 GAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ-----PSGF 1628
            G    +G P               G + S  A G P   G + G+ G++G      P G 
Sbjct: 921  GPKGDAGQP---------------GEKGSPGAQGPPGAPGPL-GIAGITGARGLAGPPGM 964

Query: 1629 PDTSGE--TSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP- 1685
            P   G     GV   SG   G  G+SGE      G   P G+  L+G T+G P   G P 
Sbjct: 965  PGPRGSPGPQGVKGESG-KPGANGLSGER-----GPPGPQGLPGLAG-TAGEPGRDGNPG 1017

Query: 1686 -SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEG--------- 1735
              GLPG  G+  G  D     + G+  + G       +     +  + E G         
Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077

Query: 1736 -LGSVELSGL--PSGEADLSGKSGMVDVSGQ--FSGTVDSSGFTSQTPEFSGLPSGIAEV 1790
              GS    G   P G+   +G+ G   + G   F G   + G    +P  +G    I   
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG----SPGPAGQQGAIGSP 1133

Query: 1791 SGESSRAEIGSSLPSGAYYGSGTP 1814
                 R  +G S P G    SG P
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHP 1157


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  142 bits (357), Expect = 5e-33
 Identities = 335/1330 (25%), Positives = 444/1330 (33%), Gaps = 242/1330 (18%)

Query: 625  GWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPG 684
            G L  G   +P +   P   G  PG++     P  TG P P               P P 
Sbjct: 168  GMLLKGERGFPGIPGTPGPPG-LPGLQGPVGPPGFTGPPGP------------PGPPGPP 214

Query: 685  EEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEP 744
             E+G    S  G +     Q V G   VP + +             +F T+ E   + EP
Sbjct: 215  GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKG--------DFATKGEKGQKGEP 266

Query: 745  AYTPVGTSPLPGI----LPTWP-PTGAATEESTEGPSATE-VPSASEEPSPSEVPFPSEE 798
                 G   +PG+     P  P P G   ++  +G   +   P     P       P  E
Sbjct: 267  -----GFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGE 321

Query: 799  PSPSEEPFPSVRPFPSVELFPSEE------PFPSKEPSPSEEPSASEEPYTPSPPVPSWT 852
               +  P P      +  L    E      P P  EP P   P    +P  P  PVP   
Sbjct: 322  KGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPG-- 379

Query: 853  ELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGL 912
                   ++GAP   G+    GD            G   + LP G     GL    GS  
Sbjct: 380  -------QAGAPGFPGERGEKGD-----------RGFPGTSLP-GPSGRDGLPGPPGS-- 418

Query: 913  PVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGD 972
            P   G P      +E    P   + P G     G    +G+  G      L     G   
Sbjct: 419  PGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE-KGQKGESCLICDIDGYRG 477

Query: 973  LSGL--PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDI 1030
              G   P GE+     PG +   GLP  +       GV  + G P G       PG +  
Sbjct: 478  PPGPQGPPGEIGFPGQPGAKGDRGLPGRD-------GVAGVPG-PQGTPGLIGQPGAK-- 527

Query: 1031 SGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS 1088
             G P     +    G +   G P   G      +PG +   GLP G      + G++   
Sbjct: 528  -GEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP-GPKGSPGSVGLKGER 585

Query: 1089 GLPSGEVLETAAPGVEDISGLPSGEVLETAAP-GVEDISGLPSGEVLETAAPGVEDISGL 1147
            G P G       PG    +G P       A P G +  +G P G      +PG+    G 
Sbjct: 586  GPPGG----VGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGG----PGSPGLPGPKGE 637

Query: 1148 PSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1205
            P   V     PG E + G P   G   +   PG     GLP GE      PG+    G P
Sbjct: 638  PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLP-GEKGAVGQPGI----GFP 692

Query: 1206 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE 1265
                     PG + + GLP G++     PG    +GLP         PGV+   G P   
Sbjct: 693  -------GPPGPKGVDGLP-GDMGPPGTPGRPGFNGLPGN-------PGVQGQKGEPG-- 735

Query: 1266 VLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS--GEVLETTAPGVDEISGLPSGEV 1323
                  PG++ + GLP         PG +   G+P   GE      PG+  I G P    
Sbjct: 736  ---VGLPGLKGLPGLPG----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788

Query: 1324 L--ETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPS-GGEVLEISVSGVEDISGLPSGE 1380
            L     +PGV  I   P G            LSG P   GE       G+ D+ G P G+
Sbjct: 789  LPGSVGSPGVPGIG--PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGL-DMPG-PKGD 844

Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440
                   GI   S LP   G +    G   +   P  +  + +  +     S  P G  G
Sbjct: 845  KGAQGLPGITGQSGLPGLPGQQ----GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPG 900

Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDL-VGSASGDL-DLGKL--- 1495
            L     + G   S  P G  GL+    G   L G P   + + +GS  G   D G+    
Sbjct: 901  LPGEKGDHGFPGSSGPRGDPGLK-GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQI 959

Query: 1496 -PSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVE 1554
             P G  GS   P T G+P G  G+      G   P G P  SG P G P +         
Sbjct: 960  GPIGEKGSRGDPGTPGVP-GKDGQAG--QPGQPGPKGDPGISGTP-GAPGL--------- 1006

Query: 1555 VVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVS 1612
                     + G G  G  G   + G+P  +      + GLP      G+   +G P + 
Sbjct: 1007 ---PGPKGSVGGMGLPGTPGEKGVPGIPGPQ-----GSPGLPGDKGAKGEKGQAGPPGIG 1058

Query: 1613 GEIPGLFGVSGQP--SGFPDTSGE--TSGVTELSGLSSGQPGISGEASGVLYGTSQPFGI 1668
              IPGL G  G    +GFP + GE    G   + G+  G PG+ G    V Y  S   G+
Sbjct: 1059 --IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM-PGSPGLKGSPGSVGYPGSP--GL 1113

Query: 1669 TDLSGETSGVPDLSGQP-----SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLV 1723
                G+  G+P L G P     +GLPG  G T          + G   S+G         
Sbjct: 1114 PGEKGD-KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG--------- 1163

Query: 1724 EVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPE--FS 1781
                   K E GL      G P  + D  G  G V     F G   S G      E  F 
Sbjct: 1164 ------EKGEPGLPGRGFPGFPGAKGD-KGSKGEVG----FPGLAGSPGIPGSKGEQGFM 1212

Query: 1782 GLPS-----GIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPT 1836
            G P      G+    G ++    G   P G     G P                      
Sbjct: 1213 GPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM------------------- 1253

Query: 1837 AQEAGEGPSGILELSGAHS--------GAPDMSGEHS--GFLDLSGL--QSGLIEPSGE- 1883
                  GP G+  + G           GAP + G     GF  + G+    G+    G+ 
Sbjct: 1254 ------GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDM 1307

Query: 1884 -PPGTPYFSG 1892
             PPG P F G
Sbjct: 1308 GPPGVPGFQG 1317



 Score =  115 bits (289), Expect = 4e-25
 Identities = 266/1067 (24%), Positives = 351/1067 (32%), Gaps = 202/1067 (18%)

Query: 743  EPAYT---------PVGTSPLPGILPTWPPTGAATEESTEGPSAT-------EVPSASEE 786
            +P YT         P G    PGI       G   E+  +G S           P   + 
Sbjct: 424  QPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQG 483

Query: 787  PSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSP 846
            P P E+ FP +  +  +   P       V             P P   P    +P     
Sbjct: 484  P-PGEIGFPGQPGAKGDRGLPGRDGVAGV-------------PGPQGTPGLIGQPGAKGE 529

Query: 847  PVPSWTELPSSGEES-----GAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGL-----PS 896
            P   + +L   G++      G P ++G   GS    GH    G      + GL     P 
Sbjct: 530  PGEFYFDLRLKGDKGDPGFPGQPGMTGR-AGSPGRDGHPGLPGPKGSPGSVGLKGERGPP 588

Query: 897  GDLDSSGLTSTVGSGLPVESGL--PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDL 954
            G +   G     G   P   G   P GD+ +  +P  P    LP      +G    +  L
Sbjct: 589  GGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGP----KGEPGKIVPL 644

Query: 955  SGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL 1014
             G P  E L  S    G     P G+      PG     GLP GE      PG+    G 
Sbjct: 645  PGPPGAEGLPGSPGFPG-----PQGD---RGFPGTPGRPGLP-GEKGAVGQPGI----GF 691

Query: 1015 PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1074
            P         PG + + GLP G++     PG    +GLP         PGV+   G P  
Sbjct: 692  PG-------PPGPKGVDGLP-GDMGPPGTPGRPGFNGLPGN-------PGVQGQKGEPG- 735

Query: 1075 EVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGE 1132
                   PG++ + GLP         PG +   G+P   GE      PG++ I G P   
Sbjct: 736  ----VGLPGLKGLPGLPG----IPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPP 787

Query: 1133 VL--ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSG 1188
             L     +PGV  I   P G        G   +SG P   GE      PG+ D+ G P G
Sbjct: 788  GLPGSVGSPGVPGIG--PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGL-DMPG-PKG 843

Query: 1189 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-----GEVLETAAPGVEDISGLP 1243
            +      PG+   SGLP G   +  APG+    G        G   +  +PG     GLP
Sbjct: 844  DKGAQGLPGITGQSGLP-GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLP 902

Query: 1244 SGEVLETAAPGVEDISGLPS-----GEVLETAAPGVEDISGL-----------------P 1281
             GE  +   PG     G P      G+V     PG  D   +                 P
Sbjct: 903  -GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGP 961

Query: 1282 SGEVLETTAPGVEEISGL-----------PSGEVLETTAPGVDEISGLPSGEVLETTAPG 1330
             GE      PG   + G            P G+   +  PG   + G P G V     PG
Sbjct: 962  IGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPG-PKGSVGGMGLPG 1020

Query: 1331 VEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVS--------GVEDISGLPSGEVV 1382
                 G+P     + S    GD       G+     +         G + I+G P G   
Sbjct: 1021 TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFP-GSPG 1079

Query: 1383 ETSASGIEDVSELPSGEGLETSAS--GVEDLSRLPSGEEVLEISASGFGDLSGLPS--GG 1438
            E    G   +  +P   GL+ S    G      LP      E    G   L G+P   G 
Sbjct: 1080 EKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG-----EKGDKGLPGLDGIPGVKGE 1134

Query: 1439 EGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPS-------------GKEDLVG- 1484
             GL  +    G        G +G+  SA G +   GLP              G +  VG 
Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDGIPGSA-GEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193

Query: 1485 ---SASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS- 1540
               + S  +   K   G +G        GLP G  G  +    G   P G P   GLP  
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLP-GSPGHATEGPKGDRGPQGQPGLPGLPGP 1252

Query: 1541 ----GFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGL- 1595
                G P +  V                  +G  G  G   I G P     I+G    + 
Sbjct: 1253 MGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG----ITGSKGDMG 1308

Query: 1596 PSGTELSGQASGSPDVSG--------EIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSG 1647
            P G        G P + G         +PG  G+ G P G P       G   L G   G
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPP-GPPGPYDIIKGEPGLPG-PEG 1366

Query: 1648 QPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGA 1694
             PG+ G     L G   P G   ++G   G+P     P G+PGF GA
Sbjct: 1367 PPGLKG-----LQGLPGPKGQQGVTGLV-GIPG----PPGIPGFDGA 1403



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 81/291 (27%), Positives = 103/291 (35%), Gaps = 52/291 (17%)

Query: 1616 PGLFGVSGQPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGTSQPFGITDLSG 1673
            PG  G +G+P G P T G T G    SG   + G PGI G+      G   P GI   +G
Sbjct: 75   PGQKGDTGEP-GLPGTKG-TRGPPGASGYPGNPGLPGIPGQD-----GPPGPPGIPGCNG 127

Query: 1674 ETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEE 1733
             T G     G P GLPGF+G   G P L  G     GE  G          V     K E
Sbjct: 128  -TKGERGPLGPP-GLPGFAG-NPGPPGL-PGMKGDPGEILG---------HVPGMLLKGE 174

Query: 1734 EGLGSVELSGLPSGEADLSGKSGMVDVSGQFS--------GTVDSSGFTSQTPEFSGLPS 1785
             G   +  +  P G   L G  G    +G           G     G + Q P+      
Sbjct: 175  RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234

Query: 1786 GIA---EVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGE 1842
            G++    V G++   E G     G     G P       + ++   E     P  +   +
Sbjct: 235  GVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKG--EPGKPGPRGKPGKD 292

Query: 1843 GPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGE-----PPGTP 1888
            G  G         G+P   GE  G+  L G Q     P GE     PPG P
Sbjct: 293  GDKG-------EKGSPGFPGE-PGYPGLIGRQG----PQGEKGEAGPPGPP 331


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  142 bits (357), Expect = 5e-33
 Identities = 297/1130 (26%), Positives = 418/1130 (36%), Gaps = 209/1130 (18%)

Query: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900
            P  P PP P +       +ESG P + G+        G+L   G + GD  SG  + D  
Sbjct: 435  PGPPGPPSPEFETETLHNKESGFPGLRGE----QGPKGNLGLKG-IKGD--SGFCACD-- 485

Query: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTV-GELPS-GAEILEGSASGVGDLSGLP 958
              G+ +T   G P E G P G    I  P      G+  S GA+   G+   VG L   P
Sbjct: 486  -GGVPNT---GPPGEPG-PPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG--P 538

Query: 959  SGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018
            SG   +     +  + G+P G+  ++ + G   + G P     +   PG+  + GLP   
Sbjct: 539  SGPKGKKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPG----KDGVPGLPGLPGLPGDG 593

Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGV--EDISGLPSGEVLETTAPGVEDISGLPSGEV 1076
                  PG + + GLP GE      PG+    + GLP    L    PG +   GLP  + 
Sbjct: 594  --GQGFPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQG 646

Query: 1077 LE----TTAPGVEDISGLPSGEVLETAAPGVEDISGLP--------SGEVLETAAPGVED 1124
            L      T P +   S  PSG       PG +   GLP        SG   E  +PG+  
Sbjct: 647  LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 706

Query: 1125 ISGLPS-----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1179
            +  LP      GE      PG+    GLP G +     PG +  +G   G   E  APG 
Sbjct: 707  LPELPGFPGPRGEKGLPGFPGLPGKDGLP-GMIGSPGLPGSKGATGDIFG--AENGAPGE 763

Query: 1180 EDISGLP--SGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPG 1235
            + + GL    G + ++  PG++ + G P   G   E  +PG     G P G    +   G
Sbjct: 764  QGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP-GTPGSSGPYG 822

Query: 1236 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295
            ++  SGLP        APG   ISG P  +       G     G P G +++   PG++ 
Sbjct: 823  IKGKSGLP-------GAPGFPGISGHPGKK-------GTRGKKG-PPGSIVKKGLPGLKG 867

Query: 1296 ISGLPSGEVLETTAPGVDEISGLPS--------GEVLETTAPGVEEISGLPSGEVLETST 1347
            + G P G V    +PG   ++GLP+        G V     PG+  + G+P    L+   
Sbjct: 868  LPGNP-GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIP 926

Query: 1348 SAVGDLSGLPSGGEVLEISVSGVEDISGLPS-----------GEVVETSASGIEDVSELP 1396
             + G +      G   E    G     G+PS           G+     ++G       P
Sbjct: 927  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-P 985

Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLE-ISAS----GFGDLSGLPSGGEGLETSASEVGTD 1451
             G+  E    G   L   P    +++ +S      GF  + GLP    GL+ S+   G  
Sbjct: 986  RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLP----GLKGSSGITG-- 1039

Query: 1452 LSGLP--SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509
              G+P  SG +G+  S  G    SGLP  K D                    +GQ  E S
Sbjct: 1040 FPGMPGESGSQGIRGS-PGLPGASGLPGLKGD--------------------NGQTVEIS 1078

Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569
            G P                P G P      SGF      D  +  +       E    G 
Sbjct: 1079 GSPG---------------PKGQPG----ESGFKGTKGRDGLIGNIGFPGNKGE---DGK 1116

Query: 1570 IGISGAGEISGLPSSELDISGRAS--GLPSGTELSGQAS--GSPDVSGE-----IPGLFG 1620
            +G+SG   + G P     ++G     GLP  +   G     GSP + G       PGL G
Sbjct: 1117 VGVSGDVGLPGAPGFP-GVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1175

Query: 1621 VSGQPSGFPDTSGETS-GVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSG 1677
            ++G P G   T G     +T + G  +G PG  GE    G+  G     G+    G+  G
Sbjct: 1176 LNGLP-GTKGTHGTPGPSITGVPG-PAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD-RG 1232

Query: 1678 VPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT-------TF 1730
             P L G P+GLPG  G +  +P L++G     G       +D       P          
Sbjct: 1233 FPGLQG-PAGLPGAPGIS--LPSLIAGQPGDPGRPG----LDGERGRPGPAGPPGPPGPS 1285

Query: 1731 KEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEV 1790
              +   G     G+P G     G  G+   SG   G +   G   + P F G P  +   
Sbjct: 1286 SNQGDTGDPGFPGIP-GPKGPKGDQGIPGFSG-LPGELGLKGMRGE-PGFMGTPGKVGPP 1342

Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850
                     G + P G+    G P   PT                   EA + P G L L
Sbjct: 1343 GDPGFPGMKGKAGPRGSSGLQGDPGQTPTA------------------EAVQVPPGPLGL 1384

Query: 1851 SGAHSGAPDMSGE--HSGFLDLSGLQS-----GLIEPSGEPPGTPYFSGD 1893
             G   G P ++G+    G + L G +      G   PSG  PG P   GD
Sbjct: 1385 PGI-DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSG-LPGPPGALGD 1432



 Score =  114 bits (285), Expect = 1e-24
 Identities = 357/1372 (26%), Positives = 480/1372 (34%), Gaps = 301/1372 (21%)

Query: 862  GAPDVSGDFTGSGD-VSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGLP 919
            G P + G     GD V     F G + GD   GLP  D    G+T   G+ G P   G P
Sbjct: 146  GPPGLPGQKGSKGDPVLAPGSFKG-MKGD--PGLPGLD----GITGPQGAPGFPGAVG-P 197

Query: 920  SGDEERIEWPSTPTVGELPSGAEIL--EGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977
            +G    ++ P  P     P G   L  +G     GD+ GLP G      ++G  +  G P
Sbjct: 198  AGPPG-LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDV-GLP-GPAGPPPSTGELEFMGFP 254

Query: 978  SGEVLETTAPGVED---ISGLPSGEVLETTAP----GVEDISGLPSGEVLETTAPGVEDI 1030
             G+      PG +    ISG P    L TT      G + I GLP          G E +
Sbjct: 255  KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPR----GPMGSEGV 310

Query: 1031 SGLPSGEVLETTA--PGVEDISGLPSGEVLETTAPGVE---DISG-LPSGEVLETTAPGV 1084
             G P  +  + T   PG+    G+  G+  +   PG +   DI G + SG   +   PGV
Sbjct: 311  QGPPGQQGKKGTLGFPGLNGFQGI-EGQKGDIGLPGPDVFIDIDGAVISGNPGD---PGV 366

Query: 1085 EDISGLPSGEVLE-----TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA- 1138
              + GL   E ++     +  PG+  +SG+P G +     PG++   G P    +  A  
Sbjct: 367  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVP-GALGPQGFPGLKGDQGNPGRTTIGAAGL 425

Query: 1139 ------PGVEDISGLPSGEV-------LETAAPGVEDISGLPSGEVLETAAPGVEDI--- 1182
                  PG     G PS E         E+  PG+    G P G +      G       
Sbjct: 426  PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG-PKGNLGLKGIKGDSGFCAC 484

Query: 1183 -SGLPS-GEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVL 1229
              G+P+ G   E   PG   + GLP            G      APG+    G PSG   
Sbjct: 485  DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG-PSGPKG 543

Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289
            +   P +  I G+P G+  ++ + G   + G P  +      PG+  + GLP        
Sbjct: 544  KKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPGKD----GVPGLPGLPGLPGDG--GQG 596

Query: 1290 APGVEEISGLPSGEVLETTAPGV--DEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347
             PG + + GLP GE      PG+  + + GLP    L    PG +   GLP  +      
Sbjct: 597  FPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQ------ 645

Query: 1348 SAVGDLSGLP-SGGEVLEISVSGVEDISGLPS--GEVVETSASGIEDVSELPSGEGL--E 1402
                   GLP S G  L   + G    SG P   G      + G+      P   G   E
Sbjct: 646  -------GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE 698

Query: 1403 TSASGVEDLSRLPS-----GEEVLEISASGFGDLSGLPS--GGEGLETSASEVGTDLSGL 1455
              + G+  L  LP      GE+ L     G     GLP   G  GL  S    G D+ G 
Sbjct: 699  PGSPGLVHLPELPGFPGPRGEKGLP-GFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGA 756

Query: 1456 PSGREGLE-----TSASGAEDLSGLPS-----GKEDLVGSASGDLDLGKLPSGTLGSGQA 1505
             +G  G +     T   G    SGLP      GK  L+G           P G  GS   
Sbjct: 757  ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG-----------PKGERGSPGT 805

Query: 1506 PETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--GFPTVSLVDSTLVEVVTASTASE 1563
            P   G P            GS  P G+   SGLP   GFP +S                +
Sbjct: 806  PGQVGQPG---------TPGSSGPYGIKGKSGLPGAPGFPGIS------------GHPGK 844

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVSGEIPGLFGV 1621
               RG  G  G+    GLP  +        GLP    L G   + GSP V+G +P L G 
Sbjct: 845  KGTRGKKGPPGSIVKKGLPGLK--------GLPGNPGLVGLKGSPGSPGVAG-LPALSGP 895

Query: 1622 SGQPS-----GFPDTSG-----ETSGVTELSGLS-----SGQPGISGEASGVLYGTSQPF 1666
             G+       GFP   G      T G+  + G +     SG+ G  GE      G   P 
Sbjct: 896  KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD--RGNPGPV 953

Query: 1667 GITD---------LSGE--------TSGVPDLSGQPS-----GLPGFSGATSGVPDLVSG 1704
            GI           L G+        ++G P   G        G PG  GA  G+P ++ G
Sbjct: 954  GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKG 1012

Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGL----GSVELSGLPS-----------GEA 1749
             +   G                P  F    GL    GS  ++G P            G  
Sbjct: 1013 VSGKPG----------------PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSP 1056

Query: 1750 DLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
             L G SG+  + G    TV+ SG    +P   G P       GES     G+    G   
Sbjct: 1057 GLPGASGLPGLKGDNGQTVEISG----SPGPKGQP-------GESGFK--GTKGRDGLIG 1103

Query: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLD 1869
              G P +      V  +    +  AP       G  G+  + G   G P  SG H G + 
Sbjct: 1104 NIGFPGNKGEDGKVGVSGDVGLPGAP-------GFPGVAGMRG-EPGLPGSSG-HQGAIG 1154

Query: 1870 LSGLQSGLIEPSGEP-----------PGTPYFSG-DFASTTNVSGESSVAMGTSGEASGL 1917
              G   GLI P G P           PGT    G    S T V G + +  G  GE  G 
Sbjct: 1155 PLG-SPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLP-GPKGE-KGY 1211

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRP-PVTHTPQLFESSGKVSTAGDISG--ATPVLPG 1974
            P +       +    +P +  + G R  P    P     +  +S    I+G    P  PG
Sbjct: 1212 PGIG------IGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1265

Query: 1975 SGVE--------VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEAN 2026
               E            P  SS      + GF     P+  + D G P  S       E  
Sbjct: 1266 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG---ELG 1322

Query: 2027 LERSSG-LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTA 2077
            L+   G  G  G+            P + G++      G +  G P  TPTA
Sbjct: 1323 LKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQ--GDPGQTPTA 1372



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 205/862 (23%), Positives = 276/862 (32%), Gaps = 209/862 (24%)

Query: 1234 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGV 1293
            PG   I G P+G    T + G+  + G       E   PG+    G P G+      PG 
Sbjct: 52   PGPIGIQG-PTGPQGFTGSTGLSGLKG-------ERGFPGLLGPYG-PKGDKGPMGVPGF 102

Query: 1294 EEISGLPS--GEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVG 1351
              I+G+P   G+      PG+D  +G           PG +   GL     L     + G
Sbjct: 103  LGINGIPGHPGQPGPRGPPGLDGCNGTQGA----VGFPGPDGYPGLLGPPGLPGQKGSKG 158

Query: 1352 DLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDL 1411
            D    P        S  G++   GLP  + +    +G +     P   G           
Sbjct: 159  DPVLAPG-------SFKGMKGDPGLPGLDGI----TGPQGAPGFPGAVG----------- 196

Query: 1412 SRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAED 1471
               P+G   L+      G L   P G  GL                G +G E    G   
Sbjct: 197  ---PAGPPGLQGPPGPPGPLG--PDGNMGL----------------GFQG-EKGVKGDVG 234

Query: 1472 LSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSG 1531
            L G P+G       ++G+L+    P G  GS   P   G P G SG      LG+    G
Sbjct: 235  LPG-PAGPPP----STGELEFMGFPKGKKGSKGEPGPKGFP-GISGPPGFPGLGTTGEKG 288

Query: 1532 LPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591
                 G+P G P        +          +   +GT+G  G     G+   + DI   
Sbjct: 289  EKGEKGIP-GLPGPR---GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDI--- 341

Query: 1592 ASGLP--------SGTELSGQ-----ASGSPDVSGE-----------IPGLFGVSG---- 1623
              GLP         G  +SG        G P + G+           +PGL  +SG    
Sbjct: 342  --GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGA 399

Query: 1624 -QPSGFPDTSGE-------TSGVTELSG-------------------------LSSGQPG 1650
              P GFP   G+       T G   L G                           SG PG
Sbjct: 400  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 459

Query: 1651 ISGEASGVLYGTSQPFGITDLSGET------SGVPDLS--GQPS--------GLPGFSGA 1694
            + GE      G     G+  + G++       GVP+    G+P         GLPG  GA
Sbjct: 460  LRGE-----QGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 514

Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754
                 D  SG   G   + G+      L    P   K E  L +++  G+P    D SG 
Sbjct: 515  RG---DRGSGGAQGPAGAPGLV---GPLGPSGPKGKKGEPILSTIQ--GMPGDRGD-SGS 565

Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG-SSLPSGAYYGSGT 1813
             G       F G +   G     P   GLP G+    G+    E G   LP     G   
Sbjct: 566  QG-------FRGVIGEPG-KDGVPGLPGLP-GLPGDGGQGFPGEKGLPGLPGEK--GHPG 614

Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGL 1873
            P   P   L            P      +G  G+        G P   G     + L  +
Sbjct: 615  PPGLPGNGLPG-------LPGPRGLPGDKGKDGL----PGQQGLPGSKG-----ITLPCI 658

Query: 1874 QSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTE 1933
              G   PSG  PGTP F G   S   + G      G+SG         L+    + G   
Sbjct: 659  IPGSYGPSGF-PGTPGFPGPKGS-RGLPGTPG-QPGSSGSKGEPGSPGLVHLPELPGFPG 715

Query: 1934 PTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYP 1993
            P   + L   P +          GK    G I   +P LPGS      +    +E  A  
Sbjct: 716  PRGEKGLPGFPGL---------PGKDGLPGMI--GSPGLPGSKGATGDI--FGAENGAPG 762

Query: 1994 EAGFGASAAPEASREDSGSPDL 2015
            E G       +    DSG P L
Sbjct: 763  EQGLQGLTGHKGFLGDSGLPGL 784


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  142 bits (357), Expect = 5e-33
 Identities = 297/1130 (26%), Positives = 418/1130 (36%), Gaps = 209/1130 (18%)

Query: 841  PYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLD 900
            P  P PP P +       +ESG P + G+        G+L   G + GD  SG  + D  
Sbjct: 434  PGPPGPPSPEFETETLHNKESGFPGLRGE----QGPKGNLGLKG-IKGD--SGFCACD-- 484

Query: 901  SSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTV-GELPS-GAEILEGSASGVGDLSGLP 958
              G+ +T   G P E G P G    I  P      G+  S GA+   G+   VG L   P
Sbjct: 485  -GGVPNT---GPPGEPG-PPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG--P 537

Query: 959  SGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018
            SG   +     +  + G+P G+  ++ + G   + G P     +   PG+  + GLP   
Sbjct: 538  SGPKGKKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPG----KDGVPGLPGLPGLPGDG 592

Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGV--EDISGLPSGEVLETTAPGVEDISGLPSGEV 1076
                  PG + + GLP GE      PG+    + GLP    L    PG +   GLP  + 
Sbjct: 593  --GQGFPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQG 645

Query: 1077 LE----TTAPGVEDISGLPSGEVLETAAPGVEDISGLP--------SGEVLETAAPGVED 1124
            L      T P +   S  PSG       PG +   GLP        SG   E  +PG+  
Sbjct: 646  LPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVH 705

Query: 1125 ISGLPS-----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1179
            +  LP      GE      PG+    GLP G +     PG +  +G   G   E  APG 
Sbjct: 706  LPELPGFPGPRGEKGLPGFPGLPGKDGLP-GMIGSPGLPGSKGATGDIFG--AENGAPGE 762

Query: 1180 EDISGLP--SGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPG 1235
            + + GL    G + ++  PG++ + G P   G   E  +PG     G P G    +   G
Sbjct: 763  QGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP-GTPGSSGPYG 821

Query: 1236 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295
            ++  SGLP        APG   ISG P  +       G     G P G +++   PG++ 
Sbjct: 822  IKGKSGLP-------GAPGFPGISGHPGKK-------GTRGKKG-PPGSIVKKGLPGLKG 866

Query: 1296 ISGLPSGEVLETTAPGVDEISGLPS--------GEVLETTAPGVEEISGLPSGEVLETST 1347
            + G P G V    +PG   ++GLP+        G V     PG+  + G+P    L+   
Sbjct: 867  LPGNP-GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIP 925

Query: 1348 SAVGDLSGLPSGGEVLEISVSGVEDISGLPS-----------GEVVETSASGIEDVSELP 1396
             + G +      G   E    G     G+PS           G+     ++G       P
Sbjct: 926  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-P 984

Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLE-ISAS----GFGDLSGLPSGGEGLETSASEVGTD 1451
             G+  E    G   L   P    +++ +S      GF  + GLP    GL+ S+   G  
Sbjct: 985  RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLP----GLKGSSGITG-- 1038

Query: 1452 LSGLP--SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509
              G+P  SG +G+  S  G    SGLP  K D                    +GQ  E S
Sbjct: 1039 FPGMPGESGSQGIRGS-PGLPGASGLPGLKGD--------------------NGQTVEIS 1077

Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569
            G P                P G P      SGF      D  +  +       E    G 
Sbjct: 1078 GSPG---------------PKGQPG----ESGFKGTKGRDGLIGNIGFPGNKGE---DGK 1115

Query: 1570 IGISGAGEISGLPSSELDISGRAS--GLPSGTELSGQAS--GSPDVSGE-----IPGLFG 1620
            +G+SG   + G P     ++G     GLP  +   G     GSP + G       PGL G
Sbjct: 1116 VGVSGDVGLPGAPGFP-GVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1174

Query: 1621 VSGQPSGFPDTSGETS-GVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSG 1677
            ++G P G   T G     +T + G  +G PG  GE    G+  G     G+    G+  G
Sbjct: 1175 LNGLP-GTKGTHGTPGPSITGVPG-PAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGD-RG 1231

Query: 1678 VPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT-------TF 1730
             P L G P+GLPG  G +  +P L++G     G       +D       P          
Sbjct: 1232 FPGLQG-PAGLPGAPGIS--LPSLIAGQPGDPGRPG----LDGERGRPGPAGPPGPPGPS 1284

Query: 1731 KEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEV 1790
              +   G     G+P G     G  G+   SG   G +   G   + P F G P  +   
Sbjct: 1285 SNQGDTGDPGFPGIP-GPKGPKGDQGIPGFSG-LPGELGLKGMRGE-PGFMGTPGKVGPP 1341

Query: 1791 SGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILEL 1850
                     G + P G+    G P   PT                   EA + P G L L
Sbjct: 1342 GDPGFPGMKGKAGPRGSSGLQGDPGQTPTA------------------EAVQVPPGPLGL 1383

Query: 1851 SGAHSGAPDMSGE--HSGFLDLSGLQS-----GLIEPSGEPPGTPYFSGD 1893
             G   G P ++G+    G + L G +      G   PSG  PG P   GD
Sbjct: 1384 PGI-DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSG-LPGPPGALGD 1431



 Score =  114 bits (285), Expect = 1e-24
 Identities = 357/1372 (26%), Positives = 480/1372 (34%), Gaps = 301/1372 (21%)

Query: 862  GAPDVSGDFTGSGD-VSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGLP 919
            G P + G     GD V     F G + GD   GLP  D    G+T   G+ G P   G P
Sbjct: 145  GPPGLPGQKGSKGDPVLAPGSFKG-MKGD--PGLPGLD----GITGPQGAPGFPGAVG-P 196

Query: 920  SGDEERIEWPSTPTVGELPSGAEIL--EGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977
            +G    ++ P  P     P G   L  +G     GD+ GLP G      ++G  +  G P
Sbjct: 197  AGPPG-LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDV-GLP-GPAGPPPSTGELEFMGFP 253

Query: 978  SGEVLETTAPGVED---ISGLPSGEVLETTAP----GVEDISGLPSGEVLETTAPGVEDI 1030
             G+      PG +    ISG P    L TT      G + I GLP          G E +
Sbjct: 254  KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPR----GPMGSEGV 309

Query: 1031 SGLPSGEVLETTA--PGVEDISGLPSGEVLETTAPGVE---DISG-LPSGEVLETTAPGV 1084
             G P  +  + T   PG+    G+  G+  +   PG +   DI G + SG   +   PGV
Sbjct: 310  QGPPGQQGKKGTLGFPGLNGFQGI-EGQKGDIGLPGPDVFIDIDGAVISGNPGD---PGV 365

Query: 1085 EDISGLPSGEVLE-----TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA- 1138
              + GL   E ++     +  PG+  +SG+P G +     PG++   G P    +  A  
Sbjct: 366  PGLPGLKGDEGIQGLRGPSGVPGLPALSGVP-GALGPQGFPGLKGDQGNPGRTTIGAAGL 424

Query: 1139 ------PGVEDISGLPSGEV-------LETAAPGVEDISGLPSGEVLETAAPGVEDI--- 1182
                  PG     G PS E         E+  PG+    G P G +      G       
Sbjct: 425  PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQG-PKGNLGLKGIKGDSGFCAC 483

Query: 1183 -SGLPS-GEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVL 1229
              G+P+ G   E   PG   + GLP            G      APG+    G PSG   
Sbjct: 484  DGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLG-PSGPKG 542

Query: 1230 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETT 1289
            +   P +  I G+P G+  ++ + G   + G P  +      PG+  + GLP        
Sbjct: 543  KKGEPILSTIQGMP-GDRGDSGSQGFRGVIGEPGKD----GVPGLPGLPGLPGDG--GQG 595

Query: 1290 APGVEEISGLPSGEVLETTAPGV--DEISGLPSGEVLETTAPGVEEISGLPSGEVLETST 1347
             PG + + GLP GE      PG+  + + GLP    L    PG +   GLP  +      
Sbjct: 596  FPGEKGLPGLP-GEKGHPGPPGLPGNGLPGLPGPRGL----PGDKGKDGLPGQQ------ 644

Query: 1348 SAVGDLSGLP-SGGEVLEISVSGVEDISGLPS--GEVVETSASGIEDVSELPSGEGL--E 1402
                   GLP S G  L   + G    SG P   G      + G+      P   G   E
Sbjct: 645  -------GLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE 697

Query: 1403 TSASGVEDLSRLPS-----GEEVLEISASGFGDLSGLPS--GGEGLETSASEVGTDLSGL 1455
              + G+  L  LP      GE+ L     G     GLP   G  GL  S    G D+ G 
Sbjct: 698  PGSPGLVHLPELPGFPGPRGEKGLP-GFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGA 755

Query: 1456 PSGREGLE-----TSASGAEDLSGLPS-----GKEDLVGSASGDLDLGKLPSGTLGSGQA 1505
             +G  G +     T   G    SGLP      GK  L+G           P G  GS   
Sbjct: 756  ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG-----------PKGERGSPGT 804

Query: 1506 PETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--GFPTVSLVDSTLVEVVTASTASE 1563
            P   G P            GS  P G+   SGLP   GFP +S                +
Sbjct: 805  PGQVGQPG---------TPGSSGPYGIKGKSGLPGAPGFPGIS------------GHPGK 843

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQ--ASGSPDVSGEIPGLFGV 1621
               RG  G  G+    GLP  +        GLP    L G   + GSP V+G +P L G 
Sbjct: 844  KGTRGKKGPPGSIVKKGLPGLK--------GLPGNPGLVGLKGSPGSPGVAG-LPALSGP 894

Query: 1622 SGQPS-----GFPDTSG-----ETSGVTELSGLS-----SGQPGISGEASGVLYGTSQPF 1666
             G+       GFP   G      T G+  + G +     SG+ G  GE      G   P 
Sbjct: 895  KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD--RGNPGPV 952

Query: 1667 GITD---------LSGE--------TSGVPDLSGQPS-----GLPGFSGATSGVPDLVSG 1704
            GI           L G+        ++G P   G        G PG  GA  G+P ++ G
Sbjct: 953  GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAP-GLPGIIKG 1011

Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGL----GSVELSGLPS-----------GEA 1749
             +   G                P  F    GL    GS  ++G P            G  
Sbjct: 1012 VSGKPG----------------PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSP 1055

Query: 1750 DLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
             L G SG+  + G    TV+ SG    +P   G P       GES     G+    G   
Sbjct: 1056 GLPGASGLPGLKGDNGQTVEISG----SPGPKGQP-------GESGFK--GTKGRDGLIG 1102

Query: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLD 1869
              G P +      V  +    +  AP       G  G+  + G   G P  SG H G + 
Sbjct: 1103 NIGFPGNKGEDGKVGVSGDVGLPGAP-------GFPGVAGMRG-EPGLPGSSG-HQGAIG 1153

Query: 1870 LSGLQSGLIEPSGEP-----------PGTPYFSG-DFASTTNVSGESSVAMGTSGEASGL 1917
              G   GLI P G P           PGT    G    S T V G + +  G  GE  G 
Sbjct: 1154 PLG-SPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLP-GPKGE-KGY 1210

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRP-PVTHTPQLFESSGKVSTAGDISG--ATPVLPG 1974
            P +       +    +P +  + G R  P    P     +  +S    I+G    P  PG
Sbjct: 1211 PGIG------IGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPG 1264

Query: 1975 SGVE--------VSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEAN 2026
               E            P  SS      + GF     P+  + D G P  S       E  
Sbjct: 1265 LDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPG---ELG 1321

Query: 2027 LERSSG-LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTA 2077
            L+   G  G  G+            P + G++      G +  G P  TPTA
Sbjct: 1322 LKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQ--GDPGQTPTA 1371



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 205/862 (23%), Positives = 276/862 (32%), Gaps = 209/862 (24%)

Query: 1234 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGV 1293
            PG   I G P+G    T + G+  + G       E   PG+    G P G+      PG 
Sbjct: 51   PGPIGIQG-PTGPQGFTGSTGLSGLKG-------ERGFPGLLGPYG-PKGDKGPMGVPGF 101

Query: 1294 EEISGLPS--GEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVG 1351
              I+G+P   G+      PG+D  +G           PG +   GL     L     + G
Sbjct: 102  LGINGIPGHPGQPGPRGPPGLDGCNGTQGA----VGFPGPDGYPGLLGPPGLPGQKGSKG 157

Query: 1352 DLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDL 1411
            D    P        S  G++   GLP  + +    +G +     P   G           
Sbjct: 158  DPVLAPG-------SFKGMKGDPGLPGLDGI----TGPQGAPGFPGAVG----------- 195

Query: 1412 SRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAED 1471
               P+G   L+      G L   P G  GL                G +G E    G   
Sbjct: 196  ---PAGPPGLQGPPGPPGPLG--PDGNMGL----------------GFQG-EKGVKGDVG 233

Query: 1472 LSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSG 1531
            L G P+G       ++G+L+    P G  GS   P   G P G SG      LG+    G
Sbjct: 234  LPG-PAGPPP----STGELEFMGFPKGKKGSKGEPGPKGFP-GISGPPGFPGLGTTGEKG 287

Query: 1532 LPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591
                 G+P G P        +          +   +GT+G  G     G+   + DI   
Sbjct: 288  EKGEKGIP-GLPGPR---GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDI--- 340

Query: 1592 ASGLP--------SGTELSGQ-----ASGSPDVSGE-----------IPGLFGVSG---- 1623
              GLP         G  +SG        G P + G+           +PGL  +SG    
Sbjct: 341  --GLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGA 398

Query: 1624 -QPSGFPDTSGE-------TSGVTELSG-------------------------LSSGQPG 1650
              P GFP   G+       T G   L G                           SG PG
Sbjct: 399  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 458

Query: 1651 ISGEASGVLYGTSQPFGITDLSGET------SGVPDLS--GQPS--------GLPGFSGA 1694
            + GE      G     G+  + G++       GVP+    G+P         GLPG  GA
Sbjct: 459  LRGE-----QGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 513

Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754
                 D  SG   G   + G+      L    P   K E  L +++  G+P    D SG 
Sbjct: 514  RG---DRGSGGAQGPAGAPGLV---GPLGPSGPKGKKGEPILSTIQ--GMPGDRGD-SGS 564

Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIG-SSLPSGAYYGSGT 1813
             G       F G +   G     P   GLP G+    G+    E G   LP     G   
Sbjct: 565  QG-------FRGVIGEPG-KDGVPGLPGLP-GLPGDGGQGFPGEKGLPGLPGEK--GHPG 613

Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGL 1873
            P   P   L            P      +G  G+        G P   G     + L  +
Sbjct: 614  PPGLPGNGLPG-------LPGPRGLPGDKGKDGL----PGQQGLPGSKG-----ITLPCI 657

Query: 1874 QSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTE 1933
              G   PSG  PGTP F G   S   + G      G+SG         L+    + G   
Sbjct: 658  IPGSYGPSGF-PGTPGFPGPKGS-RGLPGTPG-QPGSSGSKGEPGSPGLVHLPELPGFPG 714

Query: 1934 PTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYP 1993
            P   + L   P +          GK    G I   +P LPGS      +    +E  A  
Sbjct: 715  PRGEKGLPGFPGL---------PGKDGLPGMI--GSPGLPGSKGATGDI--FGAENGAPG 761

Query: 1994 EAGFGASAAPEASREDSGSPDL 2015
            E G       +    DSG P L
Sbjct: 762  EQGLQGLTGHKGFLGDSGLPGL 783


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  133 bits (334), Expect = 2e-30
 Identities = 317/1151 (27%), Positives = 396/1151 (34%), Gaps = 246/1151 (21%)

Query: 828  EPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHL------- 880
            EP    +P A   P  PS P P     P S + +G  + SG  +  G + G +       
Sbjct: 163  EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222

Query: 881  --DFSGQLSGDRASGLPSGDLDSSGLTSTVGS-------GLPVESGLP--SGDEERIEWP 929
                 GQ  G   +G P G+    G    +GS       G P E G P  +G+   + + 
Sbjct: 223  PQGLQGQQGGAGPTG-PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281

Query: 930  STPTVGELPSGAEILEG--SASGVGDLSGLPSGEVLETSASG----------VGDLS--G 975
             +P     P GA  L G     G   L G P GEV    + G          +G L   G
Sbjct: 282  GSPGARGFP-GAPGLPGLKGHRGHKGLEG-PKGEVGAPGSKGEAGPTGPMGAMGPLGPRG 339

Query: 976  LPS--GEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLP--SGEVLETTAPGVED 1029
            +P   G +    APG     G+P   G +     PG     G P   GE   T A G E 
Sbjct: 340  MPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEG 399

Query: 1030 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS-----GEVLETTAPGV 1084
                P G+  ET  PG     GLP G +     PG +  +G P      G      +PG 
Sbjct: 400  ----PQGQRGETGPPGPVGSPGLP-GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454

Query: 1085 EDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGL--PSGEVLETAAPG 1140
            +  +G P G   +   PGV    G   P GE      PG   I G   P GE  +    G
Sbjct: 455  QGSTG-PQGIRGQPGDPGVPGFKGEAGPKGE------PGPHGIQGPIGPPGEEGKRGPRG 507

Query: 1141 VEDISGLPSGEVLETAAPGVEDI---SGLP--------------SGEVLETAAPGVEDIS 1183
                 G P G V E  APG        GLP              SG       PG     
Sbjct: 508  DPGTVG-PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566

Query: 1184 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1243
            GLP    L T  PGV+     P G++    APG +   G P G +     PG   + G P
Sbjct: 567  GLPGARGL-TGNPGVQG----PEGKLGPLGAPGEDGRPG-PPGSIGIRGQPGSMGLPG-P 619

Query: 1244 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGE 1303
             G   +   PG    +G+P     +  APG +   G PSG V     PG+       +GE
Sbjct: 620  KGSSGDPGKPGEAGNAGVPG----QRGAPGKDGEVG-PSGPV---GPPGL-------AGE 664

Query: 1304 VLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVL 1363
              E   PG     GLP         PG     G P  + +     AVG L      G   
Sbjct: 665  RGEQGPPGPTGFQGLPG-------PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPG 717

Query: 1364 EISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGLETSASGVEDLSRLPSGEEVL 1421
            E    G   I+GLP GE       G +    S  PSG   +T   G++ +     GE  +
Sbjct: 718  E---RGEPGITGLP-GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM----PGERGI 769

Query: 1422 EISASGFGDLSGLPSGGEGLETSASEVGTDLSGL--------PSGREGLETSASGAEDLS 1473
              +    GD  G+  G +G E +A   G    GL        P+G  G E    G   L 
Sbjct: 770  AGTPGPKGDRGGI--GEKGAEGTAGNDGA--RGLPGPLGPPGPAGPTG-EKGEPGPRGLV 824

Query: 1474 GLPSGKEDLVGSASGDLDLGKLP-SGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGL 1532
            G P G     GS   +   G +  +G  G    P   G P G  G+    D GS  P GL
Sbjct: 825  G-PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP-GEPGQKG--DAGSPGPQGL 880

Query: 1533 PDFSGL--PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISG 1590
                G   P+G P +                    GRGT G  GA   +G P S    +G
Sbjct: 881  AGSPGPHGPNGVPGLK------------------GGRGTQGPPGA---TGFPGS----AG 915

Query: 1591 RASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQ--------PSGFPDTSGETSGVTE 1640
            R  G P      G A   G P   G  PGL G  G         P+G P   G+     E
Sbjct: 916  RV-GPPGPAGAPGPAGPLGEPGKEGP-PGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGE 973

Query: 1641 LSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETS--GVPDLSGQPSGLPGFSGATSGV 1698
                  GQPG  G       GT+   GI  + G+    G+P L G P+G PG  G T   
Sbjct: 974  -----DGQPGPDGPPGPA--GTTGQRGIVGMPGQRGERGMPGLPG-PAGTPGKVGPTGAT 1025

Query: 1699 PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMV 1758
             D       G   S+G            P      EG         P+G     G+ G V
Sbjct: 1026 GDKGPPGPVGPPGSNG------------PVGEPGPEG---------PAGNDGTPGRDGAV 1064

Query: 1759 DVSGQF-----SGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGT 1813
               G       +G   S G    TP   G P    +     SR  IG   P G     G 
Sbjct: 1065 GERGDRGDPGPAGLPGSQG-APGTPGPVGAPGDAGQRGDPGSRGPIG---PPGRAGKRGL 1120

Query: 1814 PSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGE-HSGFLDLSG 1872
            P                            GP G     G H    D   + H GF  L G
Sbjct: 1121 P----------------------------GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152

Query: 1873 LQSGLIEPSGE 1883
            L  G   P+GE
Sbjct: 1153 L-PGPPGPNGE 1162



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 264/986 (26%), Positives = 335/986 (33%), Gaps = 199/986 (20%)

Query: 748  PVGTSPLPGILPTWPPTGA---ATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEE 804
            PVG+  LPG + T    GA        T GP  +  P  S  P  S  P       P + 
Sbjct: 412  PVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP-QGIRGQPGDP 470

Query: 805  PFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSAS------EEPYTPSPPVPSWTELPSSG 858
              P  +     E  P  EP P     P   P          +P T  PP P         
Sbjct: 471  GVPGFKG----EAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPV-------- 518

Query: 859  EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917
             E GAP   G F GS  + G     G+           G + SSG   + G  G P E G
Sbjct: 519  GERGAPGNRG-FPGSDGLPGPKGAQGE----------RGPVGSSGPKGSQGDPGRPGEPG 567

Query: 918  LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLP 977
            LP                    GA  L G+    G     P G++    A G     G P
Sbjct: 568  LP--------------------GARGLTGNPGVQG-----PEGKLGPLGAPGEDGRPG-P 601

Query: 978  SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE 1037
             G +     PG   + G P G   +   PG    +G+P     +  APG +   G PSG 
Sbjct: 602  PGSIGIRGQPGSMGLPG-PKGSSGDPGKPGEAGNAGVPG----QRGAPGKDGEVG-PSGP 655

Query: 1038 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPS--- 1092
            V     PG+       +GE  E   PG     GLP   G   E   PG + + G P    
Sbjct: 656  V---GPPGL-------AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705

Query: 1093 -----GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDIS 1145
                 GE       G   I+GLP GE       G +   G   PSG   +T  PG++   
Sbjct: 706  PLGPRGERGNPGERGEPGITGLP-GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ--- 761

Query: 1146 GLPSGEVLETAAPGVE-DISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1204
            G+P GE      PG + D  G+  GE       G +   GLP         PG       
Sbjct: 762  GMP-GERGIAGTPGPKGDRGGI--GEKGAEGTAGNDGARGLPG----PLGPPG------- 807

Query: 1205 PSGEVLETAAPGVEDISGLPS--------GEVLETAAPGVEDISGLPSGEVLETAAPGVE 1256
            P+G   E   PG   + G P         GE   T A G     G P G+      PGV+
Sbjct: 808  PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG-PDGQ------PGVK 860

Query: 1257 DISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEIS 1316
               G P G+  +  +PG + ++G P          G   + GL  G   +    G    +
Sbjct: 861  GEPGEP-GQKGDAGSPGPQGLAGSPGPH-------GPNGVPGLKGGRGTQ----GPPGAT 908

Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLP-SGGEVLEISVSGVEDISG 1375
            G P G       PG     G P+G + E        L G P S G V +   +G      
Sbjct: 909  GFP-GSAGRVGPPGPAGAPG-PAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG------ 960

Query: 1376 LPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPS--GEEVLEISASGFGDLSG 1433
             P G   +    G ED    P G       +G   +  +P   GE  +       G    
Sbjct: 961  -PPGGPGDKGDPG-EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018

Query: 1434 L-PSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492
            + P+G  G +     VG   S  P G  G E  A       G P G++  VG      D 
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN----DGTP-GRDGAVGERGDRGDP 1073

Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEY-SGVDLGSGPPSGLPDFSGLPSGFPTVSLVDST 1551
            G  P+G  GS  AP T G P G  G+     D GS  P G P  +G   G P        
Sbjct: 1074 G--PAGLPGSQGAPGTPG-PVGAPGDAGQRGDPGSRGPIGPPGRAG-KRGLPGPQ----- 1124

Query: 1552 LVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDV 1611
                       +   RG  G  G    +GL            GLP     +G+       
Sbjct: 1125 ----GPRGDKGDHGDRGDRGQKGHRGFTGL-----------QGLPGPPGPNGEQG----- 1164

Query: 1612 SGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDL 1671
            S  IPG FG  G P G    SG+      L  +  G PG+ G       G + P G    
Sbjct: 1165 SAGIPGPFGPRG-PPGPVGPSGKEGNPGPLGPI--GPPGVRGSV-----GEAGPEG---- 1212

Query: 1672 SGETSGVPDLSGQPSGLPGFSGATSG 1697
                 G P   G P G PG   A  G
Sbjct: 1213 ---PPGEPGPPG-PPGPPGHLTAALG 1234


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  128 bits (321), Expect = 8e-29
 Identities = 376/1652 (22%), Positives = 596/1652 (36%), Gaps = 277/1652 (16%)

Query: 708  GVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS-------PLPGI--- 757
            G A   +  +T++V +G+TT +   +T   +     P +    +S       PLP     
Sbjct: 1468 GQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLS 1527

Query: 758  ---------LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP- 807
                     LP   P+ A+T ++T  P       ++   +P  V  PS   +    P P 
Sbjct: 1528 SASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPV 1587

Query: 808  ---------SVRPFPSVELFPSEEPFPSKEPSP-SEEPSASEEPYTPSP----------- 846
                        P P     PS        P P ++  SAS    TP P           
Sbjct: 1588 TDTSSASKGDTTPLPVTS--PSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGH 1645

Query: 847  PVPSWTELPSSGEESGAPDVSGDFTGSGDVSGH---LDFSGQLSG--DRASGLPSGDLDS 901
              P     PSS     A  +    T S   +GH   L  +G  S   D  + LP  D+ S
Sbjct: 1646 ATPLHVTSPSSASTGHATPLPVTSTSSAS-TGHATPLPVTGLSSATTDDTTRLPVTDVSS 1704

Query: 902  SGLTSTVGSGLPVESGLPSGDEE--RIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959
            +         +   S + +GD     +  PS+ + G   S   + + S++  G  + LP 
Sbjct: 1705 ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH-ASPLLVTDASSASTGQATPLPV 1763

Query: 960  GEVLETSASGVGDL--SGLPSGEVLETTAPGVEDISGLPSGEV--LETTAPGVEDISGLP 1015
             +    S +    L  +GL S    +TT   V D+S   +G+   L  T+P         
Sbjct: 1764 TDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTT 1823

Query: 1016 SGEVLETTAPGVEDISGLP-----SGEVLETTAPGVEDISGLPSGE-----VLETTAPGV 1065
               V + ++    D + LP     S     TT+  V D S + +G      V + ++   
Sbjct: 1824 PLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883

Query: 1066 EDISGLP-----SGEVLETTAPGVEDISGLPSGE-----VLETAAPGVEDISGLP----- 1110
             D + LP     S    +TT   V D S + +G      V   ++    D + LP     
Sbjct: 1884 GDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPS 1943

Query: 1111 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE 1170
            S     T    V D S +P+G    T+ P V D S + +G    T  P V D S + +G 
Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHA--TSLP-VTDASSVSTGHA--TPLP-VTDASSVSTGH 1997

Query: 1171 VLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1230
               T  P V D S + +G+   T  P    ++ L S    +T    V D S   +G+  +
Sbjct: 1998 A--TPLP-VTDTSSVSTGQA--TPLP----VTSLSSASTGDTTPLPVTDTSSASTGQ--D 2046

Query: 1231 TAAPGVEDISGLPSGEV--LETAAPG-----------VEDISGLPSGEVLETAAPGVEDI 1277
            T  P V  +S + +G+   L   +P            V D S + +G         V D 
Sbjct: 2047 TPLP-VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLL---VTDA 2102

Query: 1278 SGLPSGEVLETTAPGVEEISGLPSGEV--LETTAPGVDEISGLPSGEVLETTAPGVEEIS 1335
            S + +G     TA  V + S L +G+   L  T+P            V +T++      +
Sbjct: 2103 SSVSTG---HATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHAT 2159

Query: 1336 GLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSEL 1395
             LP   V +TS+++ G  + LP    V + S +     + LP   V +TS++     + L
Sbjct: 2160 SLP---VTDTSSASTGHATSLP----VTDTSSASTGHATPLP---VTDTSSASTGQATPL 2209

Query: 1396 PSGEGLETSASG-----VEDLSRLPSGE----EVLEISASGFGDLSGLP-------SGGE 1439
            P       S        V D S   +G+     V  +S++  GD + LP       S G 
Sbjct: 2210 PVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGH 2269

Query: 1440 GLE---TSASEVGT-DLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKL 1495
                  TS S V T D + LP       TS S A      P    D   +++G      L
Sbjct: 2270 ATSLPVTSLSSVSTGDTTPLP------VTSPSSASTGHATPLHVTDASSASTGHAT--PL 2321

Query: 1496 PSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEV 1555
            P  +L S    +T+ LP       S    G   P  + D S + +G       D+T + V
Sbjct: 2322 PVTSLSSASTGDTTPLP---VTSPSSASTGHATPLHVTDASSVSTG-------DTTPLPV 2371

Query: 1556 VTASTASELEGRGT------IGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSP 1609
             ++S+AS   G  T         +  G+ + LP +  D S  ++G  +   ++G +S S 
Sbjct: 2372 TSSSSAS--SGHTTPLPVTDASSASTGDTTPLPVT--DTSSASTGHATHLPVTGLSSAST 2427

Query: 1610 DVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGIT 1669
              +  +P +  VS   +G       TS  +  +G ++  PG   + S V  G + P  +T
Sbjct: 2428 GDTTRLP-VTNVSSASTGHATPLPVTSTSSASTGDTTPLPGT--DTSSVSTGHTTPLLVT 2484

Query: 1670 DLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGS-GESSGITFVDTSLVEVAPT 1728
            D S  ++G  D +  P   P  +      P  V+ T S S G+++ +   + S +     
Sbjct: 2485 DASSVSTG--DTTRLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHA 2542

Query: 1729 T---FKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPS 1785
            T           +   + LP  +   +  +G        S +  S+G T+  P      +
Sbjct: 2543 TSLHVTSPSSASTGHATSLPVTDTS-AASTGHATPLPVTSTSSASTGDTTPLPVTDTYSA 2601

Query: 1786 GIAEVS----GESSRAEIGSSLP------SGAYYGSGTPSSFPTVSLVD--RTLVESVTQ 1833
               + +     ++S A  G + P      S A  G  TP      S V         VT 
Sbjct: 2602 STGQATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTS 2661

Query: 1834 APTAQEAGEGPSGILELSGAHSG------APDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887
              +A      P  + + S   +G        D S   +G      +       SG     
Sbjct: 2662 PSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSASSGHTTPL 2721

Query: 1888 PYFSGDFASTTN-----VSGESSVAMG-------------TSGEASGLPEVTLITSEFVE 1929
            P       ST +     V+  SSV+ G             ++G A+ LP  +L  S    
Sbjct: 2722 PVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSL--SSVST 2779

Query: 1930 GVTEP-----TISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPE 1984
            G T P     T S   GQ  P+  T     S   VST     G T  LP +    +S   
Sbjct: 2780 GDTTPLPVTDTSSASTGQATPLPVT-----SLSSVST-----GDTTPLPVTDTSSASTGH 2829

Query: 1985 SSSETSAYPEAGFGASAAP----EASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040
            ++S       +     A P    + S   +G   L   T     A++  ++ L V+  T 
Sbjct: 2830 ATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDT-SSASIGHATSLPVT-DTS 2887

Query: 2041 TFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI- 2099
            +   G A+     S  S +T            ATP    D +  S   +GH + L V   
Sbjct: 2888 SISTGHATPLHVTSPSSASTG----------HATPLPVTDTSSAS---TGHANPLHVTSP 2934

Query: 2100 -------STSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDAS----- 2147
                   +T +P ++ T        T L + S S + +G+ T      TSP+ AS     
Sbjct: 2935 SSASTGHATPLPVTD-TSSASTGHATPLPVTSLSSVSTGDTTPL--PVTSPSSASTGHTT 2991

Query: 2148 -IPASPEWKRESESTAAAPARSCAEEPCGAGT 2178
             +P +      +    A P  S +    G  T
Sbjct: 2992 PLPVTDTSSASTGQATALPVTSTSSASTGDTT 3023



 Score =  112 bits (281), Expect = 3e-24
 Identities = 358/1586 (22%), Positives = 570/1586 (35%), Gaps = 235/1586 (14%)

Query: 717  ETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPS 776
            +TT +P  +T+++    T P   T+     T   T      LP   P+ A+T  +T  P 
Sbjct: 2461 DTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTR-----LPVTSPSSASTGHTTPLP- 2514

Query: 777  ATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELF-PSEEPFPSKEPSPSEEP 835
             T+ PSAS   +    P P    S       S R   S+ +  PS          P  + 
Sbjct: 2515 VTDTPSAS---TGDTTPLPVTNASSL-----STRHATSLHVTSPSSASTGHATSLPVTDT 2566

Query: 836  SASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP 895
            SA+   +    PV S T   S+G+ +  P V+  ++ S   +  L  +   S       P
Sbjct: 2567 SAASTGHATPLPVTS-TSSASTGDTTPLP-VTDTYSASTGQATPLPVTDTSSASTGDTTP 2624

Query: 896  SGDLDSSGLTSTVGSGLPVE--SGLPSGDEE--RIEWPSTPTVGELPSGAEILEGSASGV 951
                D+S  ++   + LPV   S + +G      +  PS+ + G   +   + + S+   
Sbjct: 2625 LPVTDTSSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHT-TPLPVTDASSVST 2683

Query: 952  GDLSGLPSGEVLETSASGVGDLSGLP-----SGEVLETTAPGVEDISGLPSGEVLETTAP 1006
            G  + LP   V + S+   G  + LP     S     TT   V D S + +G     T+ 
Sbjct: 2684 GHATSLP---VTDASSVFTGHATSLPVTIPSSASSGHTTPLPVTDASSVSTGHA---TSL 2737

Query: 1007 GVEDISGLPSGEVLETTAPGVEDIS----------GLPSGEVLETTAPGVEDISGLPSGE 1056
             V D S + +G            +S           L S    +TT   V D S   +G+
Sbjct: 2738 PVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQ 2797

Query: 1057 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE-----VLETAAPGVEDISGLPS 1111
                T   V  +S + +G+   TT   V D S   +G      V +T++      + LP 
Sbjct: 2798 A---TPLPVTSLSSVSTGD---TTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPD 2851

Query: 1112 GEVLETAAPG------VEDISGLPSGEVLETAAPGVEDISGLPSGEV--LETAAPG---- 1159
             +   +A+ G      V D S    G    T+ P V D S + +G    L   +P     
Sbjct: 2852 TDT-SSASTGHATLLPVTDTSSASIGHA--TSLP-VTDTSSISTGHATPLHVTSPSSAST 2907

Query: 1160 -------VEDISGLPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1210
                   V D S   +G    L   +P            V +T++      + LP   V 
Sbjct: 2908 GHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLP---VT 2964

Query: 1211 ETAAPGVEDISGLP-----SGEVLETAAPGVEDISGLPSGE-----VLETAAPGVEDISG 1260
              ++    D + LP     S     T    V D S   +G+     V  T++    D + 
Sbjct: 2965 SLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSASTGDTTP 3024

Query: 1261 LPSGEVLETAAPG------VEDISGLPSGEV--LETTAPGVEE--------ISGLPSGEV 1304
            LP  +   +A+ G      V  +S + +G+   L  T+P            ++   S   
Sbjct: 3025 LPVTDT-SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSAST 3083

Query: 1305 LETTAPGVDEISGLPSGEV--LETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEV 1362
             + T   V  +S + +G+   L  T+P         S  V +TS+++ GD + LP    V
Sbjct: 3084 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLP----V 3139

Query: 1363 LEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASG-----VEDLSRLPSG 1417
             + S +   D + LP   V +TS+S   D + L   E    S        V D S   +G
Sbjct: 3140 TDTSSAYTGDTTSLP---VTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTG 3196

Query: 1418 E----EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLS 1473
                  V   S++  GD + +P       T  S V T     P    GL ++++G  D +
Sbjct: 3197 HATPLHVTSPSSASTGDTTPVP------VTDTSSVSTG-HATPLPVTGLSSASTG--DTT 3247

Query: 1474 GLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLP 1533
             LP    D+  +++G      LP     S    +T  LP       S    G   P  + 
Sbjct: 3248 RLP--VTDISSASTGQAT--PLPVTNTSSVSTGDTMPLP---VTSPSSASTGHATPLPVT 3300

Query: 1534 DFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRAS 1593
              S   +G  T   V ST       +T   +    +   +  G+ + LP +    +    
Sbjct: 3301 STSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSS---ASTGDTTPLPVTSPSSASTGH 3357

Query: 1594 GLPSGTELSGQASGSPDVSGEIPGLFGVS---GQPSGFPDTSGETSG------VTELSGL 1644
              P    +   AS     +  + G    S     P    DTS  ++G      VT LS +
Sbjct: 3358 TTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSV 3417

Query: 1645 SSGQ--PGISGEASGVLYGTSQPFGITDLSGETSG------VPDLSGQPSGLPGFSGATS 1696
            S+G   P    +AS    G + P  +T LS  ++G      V D S   +G         
Sbjct: 3418 STGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTG--------H 3469

Query: 1697 GVPDLVSGTTSGS-GESSGITFVDTSLVEVAPTTFKEEEGLGSVELSG-LPSGEADLSGK 1754
              P  V+ T+S S G+++ +   DTS       T      L SV      P    D S  
Sbjct: 3470 ATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSV 3529

Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTP 1814
            S     +G  +    +   ++ T + + LP      +       +  ++PS +  G  TP
Sbjct: 3530 S-----TGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTP 3584

Query: 1815 SSFPTVSLVDRTLVE--SVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFL---D 1869
                + S V    V    VT   +A      P  +   S A +G       H+  L   D
Sbjct: 3585 LPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTG-------HATPLLVTD 3637

Query: 1870 LSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVE 1929
             S + +G   P    P T   S     TT +   +  +  ++G+A+ LP  +L  S    
Sbjct: 3638 ASSVSTGHATPL---PVTDASSASTGDTTPLP-VTDTSSASTGQATPLPVTSL--SSVST 3691

Query: 1930 GVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSET 1989
            G T P    +         TP        VST     G T  LP +       P S+S  
Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVST-----GDTMPLPVTS------PSSASTG 3740

Query: 1990 SAYPEAGFGASAAPEASREDSGSPDLSETTSAF--HEANLERSSGLGVS-GSTLTFQEGE 2046
             A P    G S+   AS  D+    +++T+SA   H   L  +     S   T      +
Sbjct: 3741 HATPLPVTGLSS---ASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTD 3797

Query: 2047 ASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI------- 2099
             S+A   +G +T      T +      TP    D + +S   +GH + L V         
Sbjct: 3798 VSSAS--TGHATPLPVTSTSSASTGDTTPLPVTDTSSVS---TGHATSLPVTSRSSASTG 3852

Query: 2100 -STSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDAS------IPASP 2152
             +T +P ++ T        T L + S+S + +G  T      TSP+ AS      +P + 
Sbjct: 3853 HATPLPVTD-TSSVSTGHATPLPVTSTSSVSTGHATPL--PVTSPSSASTGHATPVPVTS 3909

Query: 2153 EWKRESESTAAAPARSCAEEPCGAGT 2178
                 +  T   P  + +    G  T
Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHAT 3935



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 329/1588 (20%), Positives = 554/1588 (34%), Gaps = 242/1588 (15%)

Query: 693  SPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTS 752
            +PS      + +V   V+A+    E T   S  TT  L  TT    QT+W          
Sbjct: 520  NPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTT--LPKTTGAGAQTQWTQE------- 570

Query: 753  PLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPF 812
                       TG   E     PS +         SPS  P      S      PS    
Sbjct: 571  -----------TGTTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPST--- 616

Query: 813  PSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTG 872
                   +     S   SP E P+ S+  +         T+ P + +ES         T 
Sbjct: 617  -------NHSTIHSTSTSPQESPAVSQRGH---------TQAPQTTQESQTTRSVSPMTD 660

Query: 873  SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPST- 931
            +  V+     S   SG   S +   D  +    +T           P+GD    + P+T 
Sbjct: 661  TKTVTTP-GSSFTASGHSPSEIVPQDAPTISAATTFAPA-------PTGDGHTTQAPTTA 712

Query: 932  ---------PTVGELPSGAEILEGS-----ASGVGDLSGLPSGEVLETSASGVGD-LSGL 976
                      T+G  PSG   L  +     A+ V    G P G+    SAS   D  + +
Sbjct: 713  LQAAPSSHDATLG--PSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAM 770

Query: 977  PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1036
                  E+T    +  +  P+     TT+ G    S   S     TT  G E IS   SG
Sbjct: 771  THTHQAESTEASGQTQTSEPASSGSRTTSAGTATPS---SSGASGTTPSGSEGIS--TSG 825

Query: 1037 EVLE-TTAPGVEDISGLPSGEVLETTAP--GVEDISGLPSGEVLETTAPGVEDIS--GLP 1091
            E    ++ P  +  +   + E+L  +A    +   +G+ S  V  T  P + + S  G P
Sbjct: 826  ETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRP 885

Query: 1092 SGEVLETAAPGVEDISGLPSGEVLETAA----PGVEDISGLPSGEVLETAAPGVEDISGL 1147
            +G+   T+          PS    ETAA       +        + +  A+   +  S +
Sbjct: 886  TGQSSPTS----------PSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTV 935

Query: 1148 PSGEVLETA----APGVEDISGLPSGEVLETAAPGVEDISGLP-----SGEVLETAAPGV 1198
            P      T+    +P  E  +  PSG         + + + LP     S     T    V
Sbjct: 936  PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHV 995

Query: 1199 EDISGLPSGEV--LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVE 1256
             D S + +G    L   +P            V +T++     ++ LP   V   ++    
Sbjct: 996  TDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP---VTSFSSASTG 1052

Query: 1257 DISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEIS 1316
            D + LP   V +T++     ++ LP   V   ++    + + LP   V +T++      +
Sbjct: 1053 DSTPLP---VTDTSSASTGHVTPLP---VTSLSSASTGDTTPLP---VTDTSSASTGHAT 1103

Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLP-------SGGEVLEISVSG 1369
             LP   V +T++      + LP   V +TS+++ G  + LP       S G    + V+ 
Sbjct: 1104 SLP---VTDTSSVSTGHTTPLP---VTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVT- 1156

Query: 1370 VEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFG 1429
              D S   +G+      + +  VS   +     TS S        P    V + S++  G
Sbjct: 1157 --DASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPL--LVTDTSSASTG 1212

Query: 1430 DLSGLPSGGEGLETSASEVGTDLS-----GLPSGREGLETSASGAEDLSGLPSGK-EDLV 1483
              + LP       T AS V TD +      +PS      T+     D S   +G+   L+
Sbjct: 1213 HATPLP------VTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLL 1266

Query: 1484 GSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFP 1543
             + +  +  G      + S  +  T  +        S    G   P  +   S   +G  
Sbjct: 1267 VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG-- 1324

Query: 1544 TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSG 1603
                 D+  + V + S+AS             G+ + LP +  D S  ++G  +   ++ 
Sbjct: 1325 -----DTMPLPVTSPSSAS------------TGDTTPLPVT--DASSVSTGHTTPLHVTD 1365

Query: 1604 QASGSPDVSGEIPGLFGVSGQPSGFPDTS------GETS--GVTELSGLSSGQ--PGISG 1653
             +S S             +GQ +  P TS      G+T+   VT  S  S+G   P +  
Sbjct: 1366 ASSAS-------------TGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 1412

Query: 1654 EASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGS-GES 1712
            + S    G + P  +TD S  ++     +  P  +P  +      P  V+ T+S S G++
Sbjct: 1413 DTSSASTGHATPLPVTDASSVST--DHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQA 1470

Query: 1713 SGITFVDTSLVEVA-----PTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGT 1767
            + +   DTS V        P T       G V    + S  +  +G +  + V+   S +
Sbjct: 1471 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSAS 1530

Query: 1768 VD-------SSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTV 1820
                     +S  ++ T + + LP   A          +  + PS A  G  TP      
Sbjct: 1531 TGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDT 1590

Query: 1821 SLVDR--TLVESVTQAPTAQEAGEGPSGILELSGAHSG---------APDMSGEHSGFLD 1869
            S   +  T    VT   +A      P  + + S A +G         A  +S  H+  L 
Sbjct: 1591 SSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLH 1650

Query: 1870 LSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS--GESSVAMGTSGEASGLPEVTLITSEF 1927
            ++   S     +G     P  S   AST + +    + ++  T+ + + LP   + ++  
Sbjct: 1651 VTSPSSA---STGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAST 1707

Query: 1928 VEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGD--ISGATPVLPGSGVEVSSVPES 1985
             +    P  S         T  P    SS     A    ++ A+    G    +     S
Sbjct: 1708 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTS 1767

Query: 1986 SSETS-AYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQE 2044
            S  T+ A P    G S+   AS +D+    +++ +SA     +        S ST     
Sbjct: 1768 SVSTAHATPLPVTGLSS---ASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSAST----- 1819

Query: 2045 GEASAAPEVSGESTTTSDVGTEAPGLPSATP---TASGDRTEISGDLSGHTSQLGVVIST 2101
            G+ +  P     S +T D  +    +PS+     T S   T+ S   +GH + L V  ++
Sbjct: 1820 GDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDAS 1879

Query: 2102 SIPESEW-------TQQTQRPAETHLEIESSSLLYSGEETH----TVETATSPTDASIPA 2150
            S+   +        T        T L +  +S + +G  T     ++ +A++     +P 
Sbjct: 1880 SVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPV 1939

Query: 2151 SPEWKRESESTAAAPARSCAEEPCGAGT 2178
            +      S  T   P    +  P G  T
Sbjct: 1940 TSPSSASSGHTTPLPVTDASSVPTGHAT 1967



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 215/940 (22%), Positives = 328/940 (34%), Gaps = 150/940 (15%)

Query: 1266 VLETAAPGVEDISGLPSG--EVLETTAPGVEEISGLPS--GEVLETTAPGVDEISGLPSG 1321
            V+ETA P  E  +  PS     L  T+  +   +   S  G   ET+  G +  S  P  
Sbjct: 110  VMETAPPD-EMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETSTAGTE--SSTPVT 166

Query: 1322 EVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVED-ISGLPSGE 1380
              +  TA G E  S   S       TSA        S     E   S +    +  PS  
Sbjct: 167  SAVSITA-GQEGQSRTTSWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFS 225

Query: 1381 VVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGF-----GDLSGLP 1435
                + +G       PSGE   +S   V + S + S E++   +++G      G+ S +P
Sbjct: 226  PSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTS-EKITVTTSTGSTLGNPGETSSVP 284

Query: 1436 SGGEGLE-TSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGK 1494
              G  +  TSA+ V  D    P G+     S +  +D +      +      +    +  
Sbjct: 285  VTGSLMPVTSAALVTFD----PEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINT 340

Query: 1495 LPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVE 1554
            L   TL           PSGF+   SG       PSG    S  PS      LV S +  
Sbjct: 341  L--NTLTPVTTSTVLSSPSGFNP--SGTVSQETFPSGETTTSS-PSSVSNTFLVTSKVFR 395

Query: 1555 VVTASTASELEGRGTIGISGAGEISGLPSS--------ELDISGRASGLP---------- 1596
            + T S  S L       +S +G IS + S          L  +   S LP          
Sbjct: 396  MPT-SRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQ 454

Query: 1597 --SGTELSGQ----ASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPG 1650
               G E +G+    +S SP VS EI  L   +  PS F      T   TEL   S+G   
Sbjct: 455  QSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAAT 514

Query: 1651 --ISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706
              ++G  S    GT    P  ++ + GE       S   + LP  +GA +         T
Sbjct: 515  RLVTGNPSTGTAGTIPRVPSKVSAI-GEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGT 573

Query: 1707 SGSGESSGITFVDTSLVEVA--PTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQF 1764
            +G    S  ++  T +++ A  P++    +   S +++  PS        +     S Q 
Sbjct: 574  TGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHST---STSPQE 630

Query: 1765 SGTVDSSGFTS--QTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSG-TPSSFPTVS 1821
            S  V   G T   QT + S     ++ ++   +    GSS  +  +  S   P   PT+S
Sbjct: 631  SPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTIS 690

Query: 1822 L-------------VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFL 1868
                            +    ++  AP++ +A  GPSG   LS             +G L
Sbjct: 691  AATTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLS------------KTGAL 738

Query: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFV 1928
             L+   + ++   G P G                       TS  AS  P+     +   
Sbjct: 739  TLA---NSVVSTPGGPEG---------------------QWTSASASTSPDTAAAMTH-- 772

Query: 1929 EGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSE 1988
                              TH  +  E+SG+  T+   S  +          ++ P SS  
Sbjct: 773  ------------------THQAESTEASGQTQTSEPASSGSRTTSAG----TATPSSSGA 810

Query: 1989 TSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEAS 2048
            +   P    G S + E +R  S     S TT +  E     +S   +  ST     G AS
Sbjct: 811  SGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVST-----GMAS 865

Query: 2049 AA------PEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTS 2102
            +       P +S  ST     G  +P  PSA+P  +   + ++      TS+    IS +
Sbjct: 866  SIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLA 925

Query: 2103 IPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATS 2142
               S+ T        T   I S+ L     ETHT+  + S
Sbjct: 926  ---SQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGS 962



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 184/749 (24%), Positives = 274/749 (36%), Gaps = 99/749 (13%)

Query: 758  LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVEL 817
            LP    + A+T ++T  P      +++ + +P  V  PS   S    P     P  S   
Sbjct: 3537 LPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPL----PVTSTSS 3592

Query: 818  FPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVS 877
              +    P    SPS   SAS    TP P   + +            D S   TG     
Sbjct: 3593 VSTGHVTPLHVTSPS---SASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPL 3649

Query: 878  GHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGEL 937
               D S   +GD     P    D+S  ++   + LPV S         +   ST     L
Sbjct: 3650 PVTDASSASTGDTT---PLPVTDTSSASTGQATPLPVTS---------LSSVSTGDTTPL 3697

Query: 938  PSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLP--SGEVLETTAPGVEDISGL 995
            P    + + S++  G  + LP   V   S+   GD   LP  S     T       ++GL
Sbjct: 3698 P----VTDASSASTGHATPLP---VTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGL 3750

Query: 996  PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSG 1055
             S    +TT   V D S   S      T   V D S   S    +TT   V D+S   +G
Sbjct: 3751 SSASTGDTTPLPVTDTS---SASTRHATPLPVTDTS---SASTDDTTRLPVTDVSSASTG 3804

Query: 1056 EVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1115
                T  P    ++   S    +TT   V D S + +G    T+ P V   S   +G   
Sbjct: 3805 HA--TPLP----VTSTSSASTGDTTPLPVTDTSSVSTGHA--TSLP-VTSRSSASTGHA- 3854

Query: 1116 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV--LETAAPGVEDISGLPSGEVLE 1173
             T  P V D S + +G    T  P V   S + +G    L   +P            V  
Sbjct: 3855 -TPLP-VTDTSSVSTGHA--TPLP-VTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTS 3909

Query: 1174 TAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231
            T++    D + LP  +   L T       ++   S    +T+   V D S   +G    T
Sbjct: 3910 TSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHA--T 3967

Query: 1232 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAP 1291
              P    ++ L S    +T    V D S   +G+   T  P V  +S + +G   +TT  
Sbjct: 3968 PLP----LTSLSSVSTGDTTPLPVTDTSSASTGQA--TPLP-VTSLSSVSTG---DTTPL 4017

Query: 1292 GVEEISGLPSGEVLETTAPGVDEISGLPSGE-----VLETTAPGVEEISGLPSGEVLETS 1346
             V   S   SG    TT+  V + S + +G      V  T++    + + LP   V +TS
Sbjct: 4018 PVTIPSSASSG---HTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLP---VTDTS 4071

Query: 1347 TSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSAS 1406
            +++ G  + LP    V + S +     + LP      TS S +      P      TSAS
Sbjct: 4072 SASTGHATPLP----VTDTSSASTGHATPLP-----VTSLSSVSTGHATPLAVSSATSAS 4122

Query: 1407 GVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETS--ASEVGTDLSGLPSGREGLET 1464
             V       S +  L++   G    S    GG    TS   +   T +S +PS    + T
Sbjct: 4123 TV-------SSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPS--TAMHT 4173

Query: 1465 SASGAEDLSGLPSGKEDL--VGSASGDLD 1491
             ++ A  +  LP     L   G+ +GDL+
Sbjct: 4174 RSTAA-PIPILPERGVSLFPYGAGAGDLE 4201



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 209/996 (20%), Positives = 346/996 (34%), Gaps = 150/996 (15%)

Query: 1252 APGVEDISGL------PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVL 1305
            +P V +++G       PSGE   ++   V + S + S ++  TT+ G             
Sbjct: 225  SPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVTTSTG------------- 271

Query: 1306 ETTAPGVDEISGLP-SGEVLETTAPGVEEISGLPSGEVLET-STSAVGDLSGLPSGGEVL 1363
             +T     E S +P +G ++  T+  +  ++  P G+   T S ++  D +      +  
Sbjct: 272  -STLGNPGETSSVPVTGSLMPVTSAAL--VTFDPEGQSPATFSRTSTQDTTAFSKNHQTQ 328

Query: 1364 EISVSGVEDISGLPSGEVVETSA----------SGIEDVSELPSGEGLETSASGVED--- 1410
             +  + V  I+ L +   V TS           SG       PSGE   +S S V +   
Sbjct: 329  SVETTRVSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL 388

Query: 1411 ----LSRLPSGEE-----VLEISASGFGDLSGLPSGGEGL--ETSASEVGTDLSGLPSGR 1459
                + R+P+  +       E S S  G +S + S    +    + S   +  S  P   
Sbjct: 389  VTSKVFRMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKIS 448

Query: 1460 EGLETSASGAEDLSGLPSGKEDLVGSASGDL----DLGKLPSGTLGSGQAP-ETSGLPSG 1514
                T  S   + +G P  +       S ++    +    PS     G      + LPS 
Sbjct: 449  TAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPST 508

Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPS--------GFPTVSLVDSTLVEVVTASTASELEG 1566
             +G  + +  G+           +PS        G PT     ST +   T + A + + 
Sbjct: 509  STGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGA-QTQW 567

Query: 1567 RGTIGISGAGEISGLPSSELDISGRASGLPSGTEL-----SGQASGSPDVSGEIPGLFGV 1621
                G +G   +S  PS  +    + +  PS + +     S Q + +P  +         
Sbjct: 568  TQETGTTGEALLSS-PSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTST 626

Query: 1622 SGQPS---------GFPDTSGETSGVTELSGLSSGQ----PGISGEASGVLYGTSQPFGI 1668
            S Q S           P T+ E+     +S ++  +    PG S  ASG       P   
Sbjct: 627  SPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDA 686

Query: 1669 TDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT 1728
              +S  T+  P  +G        + A    P     T    G S G +   T  + +A +
Sbjct: 687  PTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDATL---GPSGGTSLSKTGALTLANS 743

Query: 1729 TFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIA 1788
                      V   G P G+   +  S   D +   + T       +++ E SG      
Sbjct: 744  V---------VSTPGGPEGQWTSASASTSPDTAAAMTHT-----HQAESTEASGQTQTSE 789

Query: 1789 EVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGIL 1848
              S  S     G++ PS +     TPS    +S    T   S   +  +    +  + +L
Sbjct: 790  PASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTT-QSTTELL 848

Query: 1849 ELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPS--GEPPGTPYFSGDFASTTNVSGESSV 1906
              S +H   P  +G  S  +        L E S  G P G    +   AS    +  S +
Sbjct: 849  SASASHGAIPVSTGMASSIVP-GTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRM 907

Query: 1907 AM----GTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVST 1961
            A      TS  +  +   +  T  F      P      G   P T T  L  S SGK  T
Sbjct: 908  AQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFT 967

Query: 1962 AGDISGATPVLPGSGVEVSS--------VPESSSETSAY--------PEAGFGASAAP-- 2003
               IS ATP LP +    +S        V ++SS ++ +        P +       P  
Sbjct: 968  TALISNATP-LPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLP 1026

Query: 2004 --EASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTS 2061
              + S E +G       TS F  A+   S+ L V+  T +   G  +  P  S  S +T 
Sbjct: 1027 VTDTSSESTGHVTPLPVTS-FSSASTGDSTPLPVT-DTSSASTGHVTPLPVTSLSSASTG 1084

Query: 2062 D------VGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRP 2115
            D        T +     AT     D + +S   +GHT+ L V  ++S             
Sbjct: 1085 DTTPLPVTDTSSASTGHATSLPVTDTSSVS---TGHTTPLPVTDTSSASTGH-------- 1133

Query: 2116 AETHLEIESSSLLYSGEET--HTVETATSPTDASIP 2149
              T L +  +S + +G  T  H  + +++ T  + P
Sbjct: 1134 -ATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATP 1168


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  127 bits (320), Expect = 1e-28
 Identities = 298/1114 (26%), Positives = 375/1114 (33%), Gaps = 205/1114 (18%)

Query: 755  PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814
            PG++   P TG    E         +P    E      P     P     P  +V   P 
Sbjct: 342  PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 815  VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865
               FP E      E       P P         P  P PP P+   +P S E  E G P 
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 866  VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917
              G   G   + G     G          G   SG P G     GL    GS G P + G
Sbjct: 458  PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 918  LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975
               G          P +   P GA    GS    GD+   P   G+  E  + G   L G
Sbjct: 516  -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 976  LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020
            LP G   +   PG+    G P G     E   PG   + GLP              G V 
Sbjct: 574  LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072
            E    GV    G P      G+  +T T PG   + G P   G+V     PG+    GLP
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128
               G   E   PG+    GLP G       PG+    G P   G +     PG     G 
Sbjct: 693  GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746

Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175
            P GE    A PG     GLP            G       PG   + GLP   G+V    
Sbjct: 747  PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228
             PG     GLP   V     P       G   + G+P GE  +   PG+ D+ G P    
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860

Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286
             E  +PG+    G P G       PG    SG P   GE+     PG     G+P     
Sbjct: 861  -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914

Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331
             +  PG++   GL        P+GE      PG+    G          GE  E   PG+
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385
              +SG    + L       G LSG P      G      + G   + G P   G + +  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438
              G + V   P   G+  +  + G+           +  I   G     G P      G 
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093

Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488
             G++ S  + G  L GLP      G+ GL          G + +SG P G   L G   G
Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149

Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538
             +  G  P   G  G    P   G+P  +G  GE      G+  P GLP  S      GL
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG-RGTIGISGAGEISG 1580
            P                  GFP V             S    LEG +G  G  G     G
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1581 LPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----GFPDTSG 1633
            LP  E        GLP    + G+    G P + G +PGL G  G P      G P  +G
Sbjct: 1265 LPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPGLNG 1318

Query: 1634 ETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET------SGVP 1679
                    GV    G+   SG PG +G E    L G   P G+   SG++      +G P
Sbjct: 1319 MKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPP 1378

Query: 1680 DLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711
             + GQP   GLPG  G     P  + G T   G+
Sbjct: 1379 GIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1407



 Score =  119 bits (299), Expect = 3e-26
 Identities = 312/1223 (25%), Positives = 409/1223 (33%), Gaps = 217/1223 (17%)

Query: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP 807
            P G    PG LP +P T          P    +P     P P  +P      +  E  FP
Sbjct: 88   PKGIRGPPG-LPGFPGT----------PGLPGMPGHDGAPGPQGIP--GCNGTKGERGFP 134

Query: 808  SVRPFPSVELFPSEEPFPSKEPSP-----SEEPSASEEPYTPSPP----VPSWTELPSSG 858
                FP ++  P     P  +  P     S  P     P  P PP    +P  T +P   
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 859  EESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918
               G P + G                        GLP G   + GL      G   E GL
Sbjct: 195  GPPGPPGLMGP-------------------PGPPGLP-GPKGNMGLNFQGPKGEKGEQGL 234

Query: 919  --PSGDEERIEWPSTPTVGELPSGAEILEGSAS-----GVGDLSGLPSGEVLETSASGVG 971
              P G   +I     P   E   G + L G        G+    G P GE  E    G  
Sbjct: 235  QGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEP 294

Query: 972  DLSGLPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVED 1029
               G P G+  E   PG+  + G P   GE       G +  +G P    L    PG   
Sbjct: 295  GKRGKP-GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG--- 350

Query: 1030 ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1089
             +G+  GE       G   + GLP GE  E   PG++   GLP         P      G
Sbjct: 351  -TGITIGE------KGNIGLPGLP-GEKGERGFPGIQGPPGLPGPPGAAVMGP--PGPPG 400

Query: 1090 LPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL------PSGEVLETAAPGV 1141
             P   G+  +   PG+  I G P G   +  APG+    G       PS E+ E   PG 
Sbjct: 401  FPGERGQKGDEGPPGIS-IPG-PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG- 457

Query: 1142 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1201
                  P G   +    G + + G            G   ISG P G+      PG    
Sbjct: 458  ------PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG---ISG-PPGQPGLPGLPGPPGS 507

Query: 1202 SGLPS--GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS 1259
             G P   GE  +  A G + + G+P        APG     G P G++L    PG++   
Sbjct: 508  LGFPGQKGEKGQAGATGPKGLPGIPGAP----GAPGFPGSKGEP-GDIL--TFPGMKG-- 558

Query: 1260 GLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVL--ETTAPGVDEISG 1317
                GE+    APG+  + G P  + L    PG+    G P G     E   PG   + G
Sbjct: 559  --DKGELGSPGAPGLPGLPGTPGQDGL----PGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLP 1377
            LP G +     PG       P G V E     V    G P           G+    G P
Sbjct: 613  LP-GNIGPMGPPGFG-----PPGPVGEKGIQGVAGNPGQP-----------GIPGPKGDP 655

Query: 1378 SGEVVETSASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLP 1435
               + +    G+          GL  +    G   L  +P  +    I   G     G P
Sbjct: 656  GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG-P 714

Query: 1436 SGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKL 1495
             G  G+       GT       GR GLE    G     G P  K +   +  G      L
Sbjct: 715  KGFPGIPGPPGAPGTP------GRIGLE----GPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 1496 PS--GTLGSGQAPETSGLPSGFSGEYSGVDLGSGP-----PSGLPDFSGLPSGFPTVSLV 1548
            P   G LG        G P G  G  +G+D   GP     P+G P   G P G P + + 
Sbjct: 765  PGFKGALGPKGDRGFPG-PPGPPGR-TGLDGLPGPKGDVGPNGQPGPMG-PPGLPGIGVQ 821

Query: 1549 DSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQAS-- 1606
                   +           G IG  G   + G+P  + D        P G ++ G     
Sbjct: 822  GPPGPPGIP----------GPIGQPG---LHGIPGEKGDPG------PPGLDVPGPPGER 862

Query: 1607 GSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPF 1666
            GSP + G  PG  G  G P G P  +G           +SG PG  GE    + G   P 
Sbjct: 863  GSPGIPGA-PGPIGPPGSP-GLPGKAG-----------ASGFPGTKGEMG--MMGPPGPP 907

Query: 1667 GITDLSGETSGVPDLSGQPS--GLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVE 1724
            G   + G  SGVP L G     G PG  G T        G+    G       +D +L+ 
Sbjct: 908  GPLGIPGR-SGVPGLKGDDGLQGQPGLPGPTGE-----KGSKGEPGLPGPPGPMDPNLL- 960

Query: 1725 VAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLP 1784
                  K E GL  +     P G   L G  G   +SGQ  G     G     P   G P
Sbjct: 961  -GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ-PGLPGPPG-PKGNPGLPGQP 1017

Query: 1785 SGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGP 1844
              I     + +  ++G   P G   G   PS  P          +  +     Q+  +G 
Sbjct: 1018 GLIGPPGLKGTIGDMGFPGPQGV-EGPPGPSGVPG---------QPGSPGLPGQKGDKGD 1067

Query: 1845 SGILELSGAHSGAPDMSGEHS--GFLDLSGLQSGLIEPSGEP--PGTPYFSGD-----FA 1895
             GI  +     G P   GE    G+    G++  + +P G P  PGTP   G      F 
Sbjct: 1068 PGISSI--GLPGLPGPKGEPGLPGYPGNPGIKGSVGDP-GLPGLPGTPGAKGQPGLPGFP 1124

Query: 1896 STTNVSGESSVAMGTSGEASGLP 1918
             T    G   ++ G  G   GLP
Sbjct: 1125 GTPGPPGPKGIS-GPPGN-PGLP 1145



 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 188/687 (27%), Positives = 241/687 (35%), Gaps = 138/687 (20%)

Query: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798
            P+G   LPGI    PP           P    +P    +P P   +VP P  E       
Sbjct: 809  PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 799  --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828
              P P   P             FP  +        P P   L  P     P  +      
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 829  -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883
                 P P+ E  +  EP  P PP P    L  S  E G P +     G   VSG   + 
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984

Query: 884  GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937
            G L GD      SG     G     G+ GLP + GL  P G           T+G++   
Sbjct: 985  G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035

Query: 938  -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991
             P G E   G  SGV    G P      G+  +   S +G L GLP G   E   PG   
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092

Query: 992  ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051
              G+  G V +   PG+  + G P  +      PG+    G P         PG + ISG
Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137

Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107
             P    L    PG     G P   G   E   PG + I G P+G+  E   PG  +    
Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195

Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1163
            GLP  SG+  +   PG+    GL  P GE      PGV+   G P      +  P +E  
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG-----SPGPALEGP 1250

Query: 1164 SGL--PSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1219
             G   P G       PG E   GLP   G   E   PG   + GLP G   +   PG++ 
Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGLQG 1309

Query: 1220 ISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSGEV 1266
              G P  +G   +   PGV    G+           P GE      PG   + G PSG+ 
Sbjct: 1310 NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSGQS 1368

Query: 1267 L----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEISG 1317
            +    +   PG+    GL          PG +   GLP      G+      PG D   G
Sbjct: 1369 IIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421

Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLE 1344
               G+      PG   + G P  + L+
Sbjct: 1422 -RKGDPGLPGQPGTRGLDGPPGPDGLQ 1447



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 64/266 (24%), Positives = 75/266 (28%), Gaps = 40/266 (15%)

Query: 645  GDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQ 704
            G  PG+      P   GLP P        F G+   P P    G     P G       Q
Sbjct: 1207 GGLPGI------PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG---PQ 1257

Query: 705  VVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPT 764
              PG   +P  E    +P            + E     +P     G   LPG+     P 
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNG-------GIKGEKGNPGQP-----GLPGLPGLKGDQGPP 1305

Query: 765  GAATEESTEG-------PSATEVPSASEEPSPSEVP---FPSEEPSPSEEPFPSVRPFPS 814
            G        G       P    VP       PS VP    P  EP     P P   P PS
Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365

Query: 815  VELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSG--DFTG 872
                  +      +  P   P        P P  P    LP      G P  +G   F G
Sbjct: 1366 -----GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ--GLPGPTGPPGDPGRNGLPGFDG 1418

Query: 873  SGDVSGHLDFSGQLSGDRASGLPSGD 898
            +G   G     GQ       G P  D
Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDGPPGPD 1444


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  125 bits (315), Expect = 4e-28
 Identities = 298/1120 (26%), Positives = 375/1120 (33%), Gaps = 211/1120 (18%)

Query: 755  PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814
            PG++   P TG    E         +P    E      P     P     P  +V   P 
Sbjct: 342  PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 815  VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865
               FP E      E       P P         P  P PP P+   +P S E  E G P 
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 866  VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917
              G   G   + G     G          G   SG P G     GL    GS G P + G
Sbjct: 458  PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 918  LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975
               G          P +   P GA    GS    GD+   P   G+  E  + G   L G
Sbjct: 516  -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 976  LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020
            LP G   +   PG+    G P G     E   PG   + GLP              G V 
Sbjct: 574  LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072
            E    GV    G P      G+  +T T PG   + G P   G+V     PG+    GLP
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128
               G   E   PG+    GLP G       PG+    G P   G +     PG     G 
Sbjct: 693  GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746

Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175
            P GE    A PG     GLP            G       PG   + GLP   G+V    
Sbjct: 747  PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228
             PG     GLP   V     P       G   + G+P GE  +   PG+ D+ G P    
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860

Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286
             E  +PG+    G P G       PG    SG P   GE+     PG     G+P     
Sbjct: 861  -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914

Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331
             +  PG++   GL        P+GE      PG+    G          GE  E   PG+
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385
              +SG    + L       G LSG P      G      + G   + G P   G + +  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438
              G + V   P   G+  +  + G+           +  I   G     G P      G 
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093

Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488
             G++ S  + G  L GLP      G+ GL          G + +SG P G   L G   G
Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149

Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538
             +  G  P   G  G    P   G+P  +G  GE      G+  P GLP  S      GL
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG-------RGTIGISG 1574
            P                  GFP V             S    LEG       +G  G  G
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----G 1627
                 GLP  E        GLP    + G+    G P + G +PGL G  G P      G
Sbjct: 1265 PTGFQGLPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPG 1318

Query: 1628 FPDTSGETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET---- 1675
             P  +G        GV    G+   SG PG +G E    L G   P G+   SG++    
Sbjct: 1319 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1378

Query: 1676 --SGVPDLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711
              +G P + GQP   GLPG  G     P  + G T   G+
Sbjct: 1379 GDAGPPGIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1413



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 191/689 (27%), Positives = 243/689 (35%), Gaps = 136/689 (19%)

Query: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798
            P+G   LPGI    PP           P    +P    +P P   +VP P  E       
Sbjct: 809  PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 799  --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828
              P P   P             FP  +        P P   L  P     P  +      
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 829  -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883
                 P P+ E  +  EP  P PP P    L  S  E G P +     G   VSG   + 
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984

Query: 884  GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937
            G L GD      SG     G     G+ GLP + GL  P G           T+G++   
Sbjct: 985  G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035

Query: 938  -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991
             P G E   G  SGV    G P      G+  +   S +G L GLP G   E   PG   
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092

Query: 992  ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051
              G+  G V +   PG+  + G P  +      PG+    G P         PG + ISG
Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137

Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107
             P    L    PG     G P   G   E   PG + I G P+G+  E   PG  +    
Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195

Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPS--GEVLE--TAAPG 1159
            GLP  SG+  +   PG+    GL  P GE      PGV+   G P   G  LE     PG
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255

Query: 1160 VEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217
             +   G P G       PG E   GLP   G   E   PG   + GLP G   +   PG+
Sbjct: 1256 PQGPPGRP-GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGL 1313

Query: 1218 EDISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSG 1264
            +   G P  +G   +   PGV    G+           P GE      PG   + G PSG
Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSG 1372

Query: 1265 EVL----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEI 1315
            + +    +   PG+    GL          PG +   GLP      G+      PG D  
Sbjct: 1373 QSIIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1425

Query: 1316 SGLPSGEVLETTAPGVEEISGLPSGEVLE 1344
             G   G+      PG   + G P  + L+
Sbjct: 1426 GG-RKGDPGLPGQPGTRGLDGPPGPDGLQ 1453


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  125 bits (315), Expect = 4e-28
 Identities = 298/1117 (26%), Positives = 374/1117 (33%), Gaps = 208/1117 (18%)

Query: 755  PGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814
            PG++   P TG    E         +P    E      P     P     P  +V   P 
Sbjct: 342  PGLVIPRPGTGITIGEKGN----IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 815  VELFPSEEPFPSKE-------PSPSEEPSASEEPYTPSPPVPSWTELPSSGE--ESGAPD 865
               FP E      E       P P         P  P PP P+   +P S E  E G P 
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 866  VSGDFTGSGDVSGHLDFSGQLS-------GDRASGLPSGDLDSSGLTSTVGS-GLPVESG 917
              G   G   + G     G          G   SG P G     GL    GS G P + G
Sbjct: 458  PPGS-PGDKGLQGEQGVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 918  LPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS--GEVLETSASGVGDLSG 975
               G          P +   P GA    GS    GD+   P   G+  E  + G   L G
Sbjct: 516  -EKGQAGATGPKGLPGIPGAP-GAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPG 573

Query: 976  LPSGEVLETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPS-------------GEVL 1020
            LP G   +   PG+    G P G     E   PG   + GLP              G V 
Sbjct: 574  LP-GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 1021 ETTAPGVEDISGLPS-----GEVLET-TAPGVEDISGLPS--GEVLETTAPGVEDISGLP 1072
            E    GV    G P      G+  +T T PG   + G P   G+V     PG+    GLP
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 1073 S--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGL 1128
               G   E   PG+    GLP G       PG+    G P   G +     PG     G 
Sbjct: 693  GIPGSKGEPGIPGI----GLP-GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG- 746

Query: 1129 PSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPS--GEVLETA 1175
            P GE    A PG     GLP            G       PG   + GLP   G+V    
Sbjct: 747  PKGEP-GFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNG 805

Query: 1176 APGVEDISGLPSGEVLETAAP-------GVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228
             PG     GLP   V     P       G   + G+P GE  +   PG+ D+ G P    
Sbjct: 806  QPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP-GEKGDPGPPGL-DVPGPPG--- 860

Query: 1229 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPSGEVL 1286
             E  +PG+    G P G       PG    SG P   GE+     PG     G+P     
Sbjct: 861  -ERGSPGIPGAPG-PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG---- 914

Query: 1287 ETTAPGVEEISGL--------PSGEVLETTAPGVDEISGL-------PSGEVLETTAPGV 1331
             +  PG++   GL        P+GE      PG+    G          GE  E   PG+
Sbjct: 915  RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974

Query: 1332 EEISGLPSGEVLETSTSAVGDLSGLPS----GGEVLEISVSGVEDISGLPS--GEVVETS 1385
              +SG    + L       G LSG P      G      + G   + G P   G + +  
Sbjct: 975  PGVSGPKGYQGLPGDPGQPG-LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 1386 ASGIEDVSELPSGEGL--ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPS-----GG 1438
              G + V   P   G+  +  + G+           +  I   G     G P      G 
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093

Query: 1439 EGLETSASEVGTDLSGLPS-----GREGLE-----TSASGAEDLSGLPSGKEDLVGSASG 1488
             G++ S  + G  L GLP      G+ GL          G + +SG P G   L G   G
Sbjct: 1094 PGIKGSVGDPG--LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEP-G 1149

Query: 1489 DLDLGKLPS--GTLGSGQAPETSGLP--SGFSGEYSGVDLGSGPPSGLPDFS------GL 1538
             +  G  P   G  G    P   G+P  +G  GE      G+  P GLP  S      GL
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 1539 PS-----------------GFPTVSLVDSTLVEVVTASTASELEG----RGTIGISGAGE 1577
            P                  GFP V             S    LEG     G  G  G   
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGP-----PGSPGPALEGPKGNPGPQGPPGRPG 1264

Query: 1578 ISGLPSSELDISGRASGLPSGTELSGQAS--GSPDVSGEIPGLFGVSGQPS-----GFPD 1630
              GLP  E        GLP    + G+    G P + G +PGL G  G P      G P 
Sbjct: 1265 FQGLPGPE-----GPPGLPGNGGIKGEKGNPGQPGLPG-LPGLKGDQGPPGLQGNPGRPG 1318

Query: 1631 TSGETS-----GVTELSGLS--SGQPGISG-EASGVLYGTSQPFGITDLSGET------S 1676
             +G        GV    G+   SG PG +G E    L G   P G+   SG++      +
Sbjct: 1319 LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1378

Query: 1677 GVPDLSGQP--SGLPGFSGATSGVPDLVSGTTSGSGE 1711
            G P + GQP   GLPG  G     P  + G T   G+
Sbjct: 1379 GPPGIPGQPGLKGLPGPQG-----PQGLPGPTGPPGD 1410



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 191/689 (27%), Positives = 244/689 (35%), Gaps = 139/689 (20%)

Query: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPS--EVPFPSEE------- 798
            P+G   LPGI    PP           P    +P    +P P   +VP P  E       
Sbjct: 809  PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868

Query: 799  --PSPSEEP-------------FPSVR--------PFPSVEL-FPSEEPFPSKE------ 828
              P P   P             FP  +        P P   L  P     P  +      
Sbjct: 869  GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQ 928

Query: 829  -----PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFS 883
                 P P+ E  +  EP  P PP P    L  S  E G P +     G   VSG   + 
Sbjct: 929  GQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL----PGIPGVSGPKGYQ 984

Query: 884  GQLSGDRASGLPSGDLDSSGLTSTVGS-GLPVESGL--PSGDEERIEWPSTPTVGEL--- 937
            G L GD      SG     G     G+ GLP + GL  P G           T+G++   
Sbjct: 985  G-LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--------LKGTIGDMGFP 1035

Query: 938  -PSGAEILEGSASGVGDLSGLP-----SGEVLETSASGVGDLSGLPSGEVLETTAPGVED 991
             P G E   G  SGV    G P      G+  +   S +G L GLP G   E   PG   
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPGLPGQKGDKGDPGISSIG-LPGLP-GPKGEPGLPGYPG 1092

Query: 992  ISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG 1051
              G+  G V +   PG+  + G P  +      PG+    G P         PG + ISG
Sbjct: 1093 NPGI-KGSVGD---PGLPGLPGTPGAK----GQPGLPGFPGTPG-------PPGPKGISG 1137

Query: 1052 LPSGEVLETTAPGVEDISGLPS--GEVLETTAPGVEDISGLPSGEVLETAAPGVEDIS-- 1107
             P    L    PG     G P   G   E   PG + I G P+G+  E   PG  +    
Sbjct: 1138 PPGNPGL-PGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPP 1195

Query: 1108 GLP--SGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPS--GEVLE--TAAPG 1159
            GLP  SG+  +   PG+    GL  P GE      PGV+   G P   G  LE     PG
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255

Query: 1160 VEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217
             +   G P  + L    PG E   GLP   G   E   PG   + GLP G   +   PG+
Sbjct: 1256 PQGPPGRPGFQGL----PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP-GLKGDQGPPGL 1310

Query: 1218 EDISGLP--SGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISGLPSG 1264
            +   G P  +G   +   PGV    G+           P GE      PG   + G PSG
Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSG 1369

Query: 1265 EVL----ETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-----GEVLETTAPGVDEI 1315
            + +    +   PG+    GL          PG +   GLP      G+      PG D  
Sbjct: 1370 QSIIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1422

Query: 1316 SGLPSGEVLETTAPGVEEISGLPSGEVLE 1344
             G   G+      PG   + G P  + L+
Sbjct: 1423 GG-RKGDPGLPGQPGTRGLDGPPGPDGLQ 1450



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 63/266 (23%), Positives = 74/266 (27%), Gaps = 37/266 (13%)

Query: 645  GDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQ 704
            G  PG+      P   GLP P        F G+   P P    G     P G        
Sbjct: 1207 GGLPGI------PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1260

Query: 705  VVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPT 764
              PG   +P  E    +P            + E     +P     G   LPG+     P 
Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNG-------GIKGEKGNPGQP-----GLPGLPGLKGDQGPP 1308

Query: 765  GAATEESTEG-------PSATEVPSASEEPSPSEVP---FPSEEPSPSEEPFPSVRPFPS 814
            G        G       P    VP       PS VP    P  EP     P P   P PS
Sbjct: 1309 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1368

Query: 815  VELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSG--DFTG 872
                  +      +  P   P        P P  P    LP      G P  +G   F G
Sbjct: 1369 -----GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ--GLPGPTGPPGDPGRNGLPGFDG 1421

Query: 873  SGDVSGHLDFSGQLSGDRASGLPSGD 898
            +G   G     GQ       G P  D
Sbjct: 1422 AGGRKGDPGLPGQPGTRGLDGPPGPD 1447


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  124 bits (311), Expect = 1e-27
 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%)

Query: 844  PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892
            P PP PS     S G E GAP   G            F GS  V G+  F G +  D   
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 893  GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952
            G   GD+   G     G     ++    GD E    P  P     P G     G     G
Sbjct: 330  G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384

Query: 953  D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002
                 L G P    L+ S    G    D  G P   G       PG     G P   V  
Sbjct: 385  SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444

Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060
               PG   + G          +PG+  + G P GE  +L T  P +    GLP       
Sbjct: 445  KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490

Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097
              PG+  + G+P   G      +PG    +GLP                  GE L    +
Sbjct: 491  -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549

Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157
               PG   + G P  + L+   PG   + GLP G   E A  G +   G P G+     +
Sbjct: 550  VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606

Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207
            PG    +G P  G   E    G + + G P         GE+ + T  PG       P G
Sbjct: 607  PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659

Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258
                   PG +   G+P   G+  +   PG +   G+P        G   +   PG +  
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312
             G P     +   PG+    GLP  +     A PG     G P     SGE  E   PG+
Sbjct: 720  LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365
              + G P  E L     +   PG     G P G  +E    A G   L+GL   G+    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832

Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419
              +G +   G+P    SG   ET + GI     E+ P G+       G+      P GE+
Sbjct: 833  GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888

Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476
             + I   GF    G P G  G   +  + G+   G+P   G+ G    A G +   G P 
Sbjct: 889  GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943

Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526
                       G+  L G A    + G    G  G        GLP          DLGS
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586
                G P   G+P     + +  S                RGT+G  G     GLP    
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047

Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643
             + G   G P  +E  G   G P  +G+  +PG  G  G+  G P   G       E + 
Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103

Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698
             S G PG+ G+      G     G   + G   G P + G P GLPGF G+   +     
Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156

Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756
               D + G     GE        T L+   P         G+    G P G   L G+ G
Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207

Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815
             +  +G   G     GF    P   GLP  I  + G++ +R   GS    GA    G P 
Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874
            S       D+ ++     + P       GP G L   G   G P   G+  GF    G++
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318

Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913
                     G I P G   P G P   GD  +   +S   S    GT GE
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%)

Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300
            LP   VL  AAP   +       G+     A G +   G P        +PG +  +G P
Sbjct: 14   LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68

Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360
             G       PG     G P    L T + GV  ISGLP         S    L G P   
Sbjct: 69   EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113

Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418
                   +G   + G+P  SG   E    G+      P   G    A+G++     P+ E
Sbjct: 114  -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162

Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462
            E +E+ A G   L G P G +GL       G      P G  G                 
Sbjct: 163  EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514
                    G + L+G P     ++ + +G     DL   K   G +G    P  SGLP  
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574
              G   G   G     G P   G+P GFP    V                  +G  G  G
Sbjct: 282  SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321

Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632
                 G+   + DI       P+    + Q  G     G  PG  G  G   PSG P   
Sbjct: 322  LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380

Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692
            G           + G PG+ G             G       T G P  +G P GLPG  
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432

Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
            G      D+V   G     G      S GI  VD           K E GL   +   +P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800
             G   L G  G+  V G   G   ++G      +P  +GLP   G     G+   + E G
Sbjct: 484  -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857
             +L P G     G P          R  ++ +   P  +    GP G L LSG     G 
Sbjct: 542  ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597

Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917
            P   G        S    G   P+G P   P        T  V G    A G  GEA   
Sbjct: 598  PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976
            P   L  S  V G   P         PP    PQ      G +   GD     P LPG  
Sbjct: 644  PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691

Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035
             E              P  GF     P+  +   G+           E  L    GL G 
Sbjct: 692  GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080
             G       G     P   GE   + + G    PGLP    T   +
Sbjct: 741  KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  124 bits (311), Expect = 1e-27
 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%)

Query: 844  PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892
            P PP PS     S G E GAP   G            F GS  V G+  F G +  D   
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 893  GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952
            G   GD+   G     G     ++    GD E    P  P     P G     G     G
Sbjct: 330  G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384

Query: 953  D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002
                 L G P    L+ S    G    D  G P   G       PG     G P   V  
Sbjct: 385  SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444

Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060
               PG   + G          +PG+  + G P GE  +L T  P +    GLP       
Sbjct: 445  KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490

Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097
              PG+  + G+P   G      +PG    +GLP                  GE L    +
Sbjct: 491  -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549

Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157
               PG   + G P  + L+   PG   + GLP G   E A  G +   G P G+     +
Sbjct: 550  VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606

Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207
            PG    +G P  G   E    G + + G P         GE+ + T  PG       P G
Sbjct: 607  PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659

Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258
                   PG +   G+P   G+  +   PG +   G+P        G   +   PG +  
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312
             G P     +   PG+    GLP  +     A PG     G P     SGE  E   PG+
Sbjct: 720  LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365
              + G P  E L     +   PG     G P G  +E    A G   L+GL   G+    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832

Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419
              +G +   G+P    SG   ET + GI     E+ P G+       G+      P GE+
Sbjct: 833  GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888

Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476
             + I   GF    G P G  G   +  + G+   G+P   G+ G    A G +   G P 
Sbjct: 889  GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943

Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526
                       G+  L G A    + G    G  G        GLP          DLGS
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586
                G P   G+P     + +  S                RGT+G  G     GLP    
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047

Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643
             + G   G P  +E  G   G P  +G+  +PG  G  G+  G P   G       E + 
Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103

Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698
             S G PG+ G+      G     G   + G   G P + G P GLPGF G+   +     
Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156

Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756
               D + G     GE        T L+   P         G+    G P G   L G+ G
Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207

Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815
             +  +G   G     GF    P   GLP  I  + G++ +R   GS    GA    G P 
Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874
            S       D+ ++     + P       GP G L   G   G P   G+  GF    G++
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318

Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913
                     G I P G   P G P   GD  +   +S   S    GT GE
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%)

Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300
            LP   VL  AAP   +       G+     A G +   G P        +PG +  +G P
Sbjct: 14   LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68

Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360
             G       PG     G P    L T + GV  ISGLP         S    L G P   
Sbjct: 69   EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113

Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418
                   +G   + G+P  SG   E    G+      P   G    A+G++     P+ E
Sbjct: 114  -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162

Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462
            E +E+ A G   L G P G +GL       G      P G  G                 
Sbjct: 163  EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514
                    G + L+G P     ++ + +G     DL   K   G +G    P  SGLP  
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574
              G   G   G     G P   G+P GFP    V                  +G  G  G
Sbjct: 282  SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321

Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632
                 G+   + DI       P+    + Q  G     G  PG  G  G   PSG P   
Sbjct: 322  LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380

Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692
            G           + G PG+ G             G       T G P  +G P GLPG  
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432

Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
            G      D+V   G     G      S GI  VD           K E GL   +   +P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800
             G   L G  G+  V G   G   ++G      +P  +GLP   G     G+   + E G
Sbjct: 484  -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857
             +L P G     G P          R  ++ +   P  +    GP G L LSG     G 
Sbjct: 542  ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597

Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917
            P   G        S    G   P+G P   P        T  V G    A G  GEA   
Sbjct: 598  PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976
            P   L  S  V G   P         PP    PQ      G +   GD     P LPG  
Sbjct: 644  PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691

Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035
             E              P  GF     P+  +   G+           E  L    GL G 
Sbjct: 692  GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080
             G       G     P   GE   + + G    PGLP    T   +
Sbjct: 741  KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  124 bits (311), Expect = 1e-27
 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%)

Query: 844  PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892
            P PP PS     S G E GAP   G            F GS  V G+  F G +  D   
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 893  GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952
            G   GD+   G     G     ++    GD E    P  P     P G     G     G
Sbjct: 330  G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384

Query: 953  D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002
                 L G P    L+ S    G    D  G P   G       PG     G P   V  
Sbjct: 385  SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444

Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060
               PG   + G          +PG+  + G P GE  +L T  P +    GLP       
Sbjct: 445  KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490

Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097
              PG+  + G+P   G      +PG    +GLP                  GE L    +
Sbjct: 491  -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549

Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157
               PG   + G P  + L+   PG   + GLP G   E A  G +   G P G+     +
Sbjct: 550  VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606

Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207
            PG    +G P  G   E    G + + G P         GE+ + T  PG       P G
Sbjct: 607  PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659

Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258
                   PG +   G+P   G+  +   PG +   G+P        G   +   PG +  
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312
             G P     +   PG+    GLP  +     A PG     G P     SGE  E   PG+
Sbjct: 720  LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365
              + G P  E L     +   PG     G P G  +E    A G   L+GL   G+    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832

Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419
              +G +   G+P    SG   ET + GI     E+ P G+       G+      P GE+
Sbjct: 833  GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888

Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476
             + I   GF    G P G  G   +  + G+   G+P   G+ G    A G +   G P 
Sbjct: 889  GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943

Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526
                       G+  L G A    + G    G  G        GLP          DLGS
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586
                G P   G+P     + +  S                RGT+G  G     GLP    
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047

Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643
             + G   G P  +E  G   G P  +G+  +PG  G  G+  G P   G       E + 
Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103

Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698
             S G PG+ G+      G     G   + G   G P + G P GLPGF G+   +     
Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156

Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756
               D + G     GE        T L+   P         G+    G P G   L G+ G
Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207

Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815
             +  +G   G     GF    P   GLP  I  + G++ +R   GS    GA    G P 
Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874
            S       D+ ++     + P       GP G L   G   G P   G+  GF    G++
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318

Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913
                     G I P G   P G P   GD  +   +S   S    GT GE
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%)

Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300
            LP   VL  AAP   +       G+     A G +   G P        +PG +  +G P
Sbjct: 14   LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68

Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360
             G       PG     G P    L T + GV  ISGLP         S    L G P   
Sbjct: 69   EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113

Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418
                   +G   + G+P  SG   E    G+      P   G    A+G++     P+ E
Sbjct: 114  -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162

Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462
            E +E+ A G   L G P G +GL       G      P G  G                 
Sbjct: 163  EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514
                    G + L+G P     ++ + +G     DL   K   G +G    P  SGLP  
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574
              G   G   G     G P   G+P GFP    V                  +G  G  G
Sbjct: 282  SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321

Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632
                 G+   + DI       P+    + Q  G     G  PG  G  G   PSG P   
Sbjct: 322  LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380

Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692
            G           + G PG+ G             G       T G P  +G P GLPG  
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432

Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
            G      D+V   G     G      S GI  VD           K E GL   +   +P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800
             G   L G  G+  V G   G   ++G      +P  +GLP   G     G+   + E G
Sbjct: 484  -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857
             +L P G     G P          R  ++ +   P  +    GP G L LSG     G 
Sbjct: 542  ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597

Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917
            P   G        S    G   P+G P   P        T  V G    A G  GEA   
Sbjct: 598  PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976
            P   L  S  V G   P         PP    PQ      G +   GD     P LPG  
Sbjct: 644  PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691

Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035
             E              P  GF     P+  +   G+           E  L    GL G 
Sbjct: 692  GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080
             G       G     P   GE   + + G    PGLP    T   +
Sbjct: 741  KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  124 bits (311), Expect = 1e-27
 Identities = 309/1190 (25%), Positives = 409/1190 (34%), Gaps = 211/1190 (17%)

Query: 844  PSPPVPSWTELPSSGEESGAPDVSG-----------DFTGSGDVSGHLDFSGQLSGDRAS 892
            P PP PS     S G E GAP   G            F GS  V G+  F G +  D   
Sbjct: 270  PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 893  GLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVG 952
            G   GD+   G     G     ++    GD E    P  P     P G     G     G
Sbjct: 330  G-QKGDIGPPGFR---GPTEYYDTYQEKGD-EGTPGPPGPRGARGPQGPSGPPGVPGSPG 384

Query: 953  D----LSGLPSGEVLETSASGVG----DLSGLPS--GEVLETTAPGVEDISGLPSGEVLE 1002
                 L G P    L+ S    G    D  G P   G       PG     G P   V  
Sbjct: 385  SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR 444

Query: 1003 TTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGE--VLETTAPGVEDISGLPSGEVLET 1060
               PG   + G          +PG+  + G P GE  +L T  P +    GLP       
Sbjct: 445  KGPPGDHGLPGY-------LGSPGIPGVDG-PKGEPGLLCTQCPYIPGPPGLPG------ 490

Query: 1061 TAPGVEDISGLP--SGEVLETTAPGVEDISGLP-----------------SGEVL----E 1097
              PG+  + G+P   G      +PG    +GLP                  GE L    +
Sbjct: 491  -LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQ 549

Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157
               PG   + G P  + L+   PG   + GLP G   E A  G +   G P G+     +
Sbjct: 550  VGVPGDPGLRGQPGRKGLD-GIPGTPGVKGLP-GPKGELALSGEKGDQG-PPGDPGSPGS 606

Query: 1158 PGVEDISGLPS-GEVLETAAPGVEDISGLPS--------GEV-LETAAPGVEDISGLPSG 1207
            PG    +G P  G   E    G + + G P         GE+ + T  PG       P G
Sbjct: 607  PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG-------PPG 659

Query: 1208 EVLETAAPGVEDISGLPS--GEVLETAAPGVEDISGLPS-------GEVLETAAPGVEDI 1258
                   PG +   G+P   G+  +   PG +   G+P        G   +   PG +  
Sbjct: 660  PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGS 719

Query: 1259 SGLPSGEVLETAAPGVEDISGLPSGEVLETTA-PGVEEISGLP-----SGEVLETTAPGV 1312
             G P     +   PG+    GLP  +     A PG     G P     SGE  E   PG+
Sbjct: 720  LGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGL 775

Query: 1313 DEISGLPSGEVL-----ETTAPGVEEISGLPSGEVLETSTSAVG--DLSGLPSGGEVLEI 1365
              + G P  E L     +   PG     G P G  +E    A G   L+GL   G+    
Sbjct: 776  PGLPGTPGNEGLDGPRGDPGQPGPPGEQG-PPGRCIEGPRGAQGLPGLNGLK--GQQGRR 832

Query: 1366 SVSGVEDISGLP----SGEVVETSASGIE-DVSEL-PSGEGLETSASGVEDLSRLPSGEE 1419
              +G +   G+P    SG   ET + GI     E+ P G+       G+      P GE+
Sbjct: 833  GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILG----PPGED 888

Query: 1420 VLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP--SGREGLETSASGAEDLSGLP- 1476
             + I   GF    G P G  G   +  + G+   G+P   G+ G    A G +   G P 
Sbjct: 889  GV-IGMMGFPGAIG-PPGPPGNPGTPGQRGS--PGIPGVKGQRG-TPGAKGEQGDKGNPG 943

Query: 1477 ----------SGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGS 1526
                       G+  L G A    + G    G  G        GLP          DLGS
Sbjct: 944  PSEISHVIGDKGEPGLKGFAGNPGEKGN--RGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001

Query: 1527 GPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586
                G P   G+P     + +  S                RGT+G  G     GLP    
Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK-------------GKRGTLGFPGRAGRPGLPGIH- 1047

Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGV-TELSG 1643
             + G   G P  +E  G   G P  +G+  +PG  G  G+  G P   G       E + 
Sbjct: 1048 GLQG-DKGEPGYSE--GTRPGPPGPTGDPGLPGDMGKKGE-MGQPGPPGHLGPAGPEGAP 1103

Query: 1644 LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGV----- 1698
             S G PG+ G+      G     G   + G   G P + G P GLPGF G+   +     
Sbjct: 1104 GSPGSPGLPGKP-----GPHGDLGFKGIKG-LLGPPGIRG-PPGLPGFPGSPGPMGIRGD 1156

Query: 1699 --PDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSG 1756
               D + G     GE        T L+   P         G+    G P G   L G+ G
Sbjct: 1157 QGRDGIPGPAGEKGE--------TGLLRAPPGPRGNPGAQGAKGDRGAP-GFPGLPGRKG 1207

Query: 1757 MVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGES-SRAEIGSSLPSGAYYGSGTPS 1815
             +  +G   G     GF    P   GLP  I  + G++ +R   GS    GA    G P 
Sbjct: 1208 AMGDAGP-RGPTGIEGF----PGPPGLPGAI--IPGQTGNRGPPGSRGSPGAPGPPGPPG 1260

Query: 1816 SFPTVSLVDR-TLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874
            S       D+ ++     + P       GP G L   G   G P   G+  GF    G++
Sbjct: 1261 SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT-PGLPGPRGD-PGFQGFPGVK 1318

Query: 1875 S--------GLIEPSGE--PPGTPYFSGDFASTTNVSGESSVA-MGTSGE 1913
                     G I P G   P G P   GD  +   +S   S    GT GE
Sbjct: 1319 GEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 221/886 (24%), Positives = 278/886 (31%), Gaps = 161/886 (18%)

Query: 1242 LPSGEVLETAAPGV-EDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLP 1300
            LP   VL  AAP   +       G+     A G +   G P        +PG +  +G P
Sbjct: 14   LPLLLVLLAAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPG----PPGSPGQKGFTG-P 68

Query: 1301 SGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGG 1360
             G       PG     G P    L T + GV  ISGLP         S    L G P   
Sbjct: 69   EG------LPGPQGPKGFPGLPGL-TGSKGVRGISGLPG-------FSGSPGLPGTPGN- 113

Query: 1361 EVLEISVSGVEDISGLP--SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGE 1418
                   +G   + G+P  SG   E    G+      P   G    A+G++     P+ E
Sbjct: 114  -------TGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPG----AAGLKGQKGAPAKE 162

Query: 1419 EVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGL---------------- 1462
            E +E+ A G   L G P G +GL       G      P G  G                 
Sbjct: 163  EDIELDAKGDPGLPGAP-GPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGER 221

Query: 1463 ---ETSASGAEDLSGLPSGKEDLVGSASG-----DLDLGKLPSGTLGSGQAPETSGLPSG 1514
                    G + L+G P     ++ + +G     DL   K   G +G    P  SGLP  
Sbjct: 222  VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGE 281

Query: 1515 FSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISG 1574
              G   G   G     G P   G+P GFP    V                  +G  G  G
Sbjct: 282  SYGSEKGAP-GDPGLQGKPGKDGVP-GFPGSEGV------------------KGNRGFPG 321

Query: 1575 AGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQ--PSGFPDTS 1632
                 G+   + DI       P+    + Q  G     G  PG  G  G   PSG P   
Sbjct: 322  LMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP-PGPRGARGPQGPSGPPGVP 380

Query: 1633 GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1692
            G           + G PG+ G             G       T G P  +G P GLPG  
Sbjct: 381  GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG-------TPGSPGCAGSP-GLPGSP 432

Query: 1693 GATSGVPDLV--SGTTSGSG-----ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
            G      D+V   G     G      S GI  VD           K E GL   +   +P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---------KGEPGLLCTQCPYIP 483

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQ--TPEFSGLPS--GIAEVSGESS-RAEIG 1800
             G   L G  G+  V G   G   ++G      +P  +GLP   G     G+   + E G
Sbjct: 484  -GPPGLPGLPGLHGVKG-IPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1801 SSL-PSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG--AHSGA 1857
             +L P G     G P          R  ++ +   P  +    GP G L LSG     G 
Sbjct: 542  ETLQPEGQV---GVPGDPGLRGQPGRKGLDGIPGTPGVKGL-PGPKGELALSGEKGDQGP 597

Query: 1858 PDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL 1917
            P   G        S    G   P+G P   P        T  V G    A G  GEA   
Sbjct: 598  PGDPG--------SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG----APGPPGEAG-- 643

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFES-SGKVSTAGDISGATPVLPGSG 1976
            P   L  S  V G   P         PP    PQ      G +   GD     P LPG  
Sbjct: 644  PRGELSVSTPVPGPPGP-------PGPPGHPGPQGPPGIPGSLGKCGD-----PGLPGPD 691

Query: 1977 VEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL-GV 2035
             E              P  GF     P+  +   G+           E  L    GL G 
Sbjct: 692  GE-----------PGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA 740

Query: 2036 SGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGD 2080
             G       G     P   GE   + + G    PGLP    T   +
Sbjct: 741  KGEPAVAMPG-GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  121 bits (303), Expect = 9e-27
 Identities = 334/1304 (25%), Positives = 441/1304 (33%), Gaps = 243/1304 (18%)

Query: 718  TTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSA 777
            T+ V +G    ILE + +P++ TE              G L T      A  E  EG  +
Sbjct: 308  TSTVTTGLNATILERSLDPDSGTEL-------------GTLET-----KAAREDEEGDDS 349

Query: 778  TEVPS--ASEEPSPSEV---PFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPS 832
            T  P   A+E PS ++    P   E+ +  E   P+V         P   P P     PS
Sbjct: 350  TMGPDFRAAEYPSRTQFQIFPGAGEKGAKGE---PAVIEKGQQFEGPPGAPGPQGVVGPS 406

Query: 833  EEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRAS 892
              P     P  P PP P+   LP      G P + G     G V   +    Q +G    
Sbjct: 407  GPPGPPGFPGDPGPPGPA--GLP------GIPGIDGIRGPPGTV---IMMPFQFAGGSFK 455

Query: 893  GLP-------------------SGDLDSSGLTSTVGS-GLPVESGLPSGDEERIEWPSTP 932
            G P                    G     GLT   G  GLP   GL    EE  E P  P
Sbjct: 456  GPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKG--EEGAEGPQGP 513

Query: 933  TVGELPSG--AEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPS--------GEVL 982
               + P G    + +    G     GLP G+       G   L GLP         G V 
Sbjct: 514  RGLQGPHGPPGRVGKMGRPGADGARGLP-GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVG 572

Query: 983  ETTAPGVEDISGL--PSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP--SGEV 1038
            +   PG +   G   P G   +   PG   + G P G    T  PGV  I G P   G V
Sbjct: 573  QPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG-PRGSPGPTGRPGVTGIDGAPGAKGNV 631

Query: 1039 LETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLET 1098
                 PG     G    + L    PG + + G P     E   PG   I GLP G     
Sbjct: 632  GPPGEPGPPGQQGNHGSQGL----PGPQGLIGTPG----EKGPPGNPGIPGLP-GSDGPL 682

Query: 1099 AAPGVEDISGL-----PSGEVLETAAPGVEDISGL--------PSGEVLETAAPGVEDIS 1145
              PG E  +G      P G       PG   + G           GE  E   PG +   
Sbjct: 683  GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742

Query: 1146 GLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP 1205
            GL  G+  +  APG     G P G   +    G E     P G   E    GV  + G P
Sbjct: 743  GL-KGDQGKPGAPGPRGEDG-PEGPKGQAGQAGEEG----PPGSAGEKGKLGVPGLPGYP 796

Query: 1206 SGEVLETAAPGVEDISGLP--------SGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1257
                     PG +   G P         G+  +T  PG+E   G P G   E   PG   
Sbjct: 797  -------GRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERG-PPGSRGERGQPGATG 848

Query: 1258 ISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISG 1317
              G P G+V +  APG+    GLP  +      PG     G P G   +   PG     G
Sbjct: 849  QPG-PKGDVGQDGAPGIPGEKGLPGLQ----GPPGFPGPKG-PPGHQGKDGRPGHPGQRG 902

Query: 1318 LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGL- 1376
               G   +T  PG   + G P G+  E          G P  G   E  + G+E   G  
Sbjct: 903  -ELGFQGQTGPPGPAGVLG-PQGKTGEVGPLGERGPPGPP--GPPGEQGLPGLEGREGAK 958

Query: 1377 ----PSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLS 1432
                P G + +   +G+        G G +   +G++   + P G      S    G L 
Sbjct: 959  GELGPPGPLGKEGPAGLRGFPGPKGGPG-DPGPTGLKG-DKGPPGPVGANGSPGERGPLG 1016

Query: 1433 GLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492
              P+GG GL     + G++    P+G++G    + G     G P+GK+ + G        
Sbjct: 1017 --PAGGIGL---PGQSGSEGPVGPAGKKG----SRGERGPPG-PTGKDGIPG-------- 1058

Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEYSGV----------DLGSGPPSGLPDFSGLPSGF 1542
               P G LG    P  +  PSG  G+   V          D G   P G P   G P+G 
Sbjct: 1059 ---PLGPLG----PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRG-PAGH 1110

Query: 1543 PTVSLVDSTLVEVVTASTASELEG---RGTIGISGAGEISGL---PSSELDISGRASGLP 1596
            P     D             +      RG +G+ G   + GL   P  + ++    S  P
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 1597 SGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEAS 1656
             G     +    P  S   PGL G  GQP G     GE     +      G PGI G   
Sbjct: 1171 HGAP-GPRGPQGPTGSEGTPGLPGGVGQP-GAVGEKGERGDAGDPG--PPGAPGIPGPKG 1226

Query: 1657 GV-LYGTSQPFGITDLSGETSGVPDLSGQ-----PSGLPGFSGATSGVPDLVSGTTSGSG 1710
             +   G S P G     G+  G P   G      P+GLPG  G   G P  VSG     G
Sbjct: 1227 DIGEKGDSGPSGAAGPPGK-KGPPGEDGAKGSVGPTGLPGDLG-PPGDPG-VSGIDGSPG 1283

Query: 1711 ESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ------- 1763
            E      V        P     E G         PSG     G+ G     G+       
Sbjct: 1284 EKGDPGDVGGP----GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPP 1339

Query: 1764 -FSGTVDSSGFTSQT-PE-FSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTV 1820
              +G + + G   +  PE   G+P  + E     +  ++G   P G       PS  P +
Sbjct: 1340 GRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLG-------PSGLPGL 1392

Query: 1821 SLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEP 1880
                        +  T  +  +G  G++ L     G P  +GE  G   L G+Q G   P
Sbjct: 1393 ------------KGDTGPKGEKGHIGLIGL----IGPPGEAGE-KGDQGLPGVQ-GPPGP 1434

Query: 1881 SGEP-----------PGTPYFSGDFASTTNVSGESSVAMGTSGE 1913
             G+P           PG P  +G      +     S  MG  G+
Sbjct: 1435 KGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGS--MGPRGD 1476



 Score =  109 bits (272), Expect = 4e-23
 Identities = 294/1156 (25%), Positives = 391/1156 (33%), Gaps = 198/1156 (17%)

Query: 816  ELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPS---WTELPSSGEESGAPDVSGDFTG 872
            E++ S  P  S E   S +   +E P    PP P+    T   ++G  +   + S D   
Sbjct: 269  EIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLD-PD 327

Query: 873  SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTP 932
            SG   G L+                  D  G  ST+G            D    E+PS  
Sbjct: 328  SGTELGTLETKAARE------------DEEGDDSTMGP-----------DFRAAEYPSRT 364

Query: 933  TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDI 992
                 P       G     G+ + +  G+  E      G     P G V  +  PG    
Sbjct: 365  QFQIFPGA-----GEKGAKGEPAVIEKGQQFEGPPGAPG-----PQGVVGPSGPPGPPGF 414

Query: 993  SGLPS--GEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP-------SGEVLETTA 1043
             G P   G       PG++ I G P   ++           G P       +  VL+ T 
Sbjct: 415  PGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQ 474

Query: 1044 PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL-----PSGEVLET 1098
              ++     P G V  T  PG   + G P G   E  A G +   GL     P G V + 
Sbjct: 475  LSMKG----PPGPVGLTGRPGPVGLPGHP-GLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 1099 AAPGVEDISGLPSGEVLETAAPGVEDISGLPS--------GEVLETAAPGVEDISGL--P 1148
              PG +   GLP G+       G + + GLP         G V +   PG +   G   P
Sbjct: 530  GRPGADGARGLP-GDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGP 588

Query: 1149 SGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLP--SGEVLETAAPGVEDISGLPS 1206
             G   +   PG   + G P G    T  PGV  I G P   G V     PG     G   
Sbjct: 589  PGPTGQAGEPGPRGLLG-PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG 647

Query: 1207 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1266
             + L    PG + + G P     E   PG   I GLP G       PG E     P+GE 
Sbjct: 648  SQGL----PGPQGLIGTPG----EKGPPGNPGIPGLP-GSDGPLGHPGHEG----PTGEK 694

Query: 1267 LETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLET 1326
                 PG     G P    ++ T+ G   + G   GE  E   PG     GL  G+  + 
Sbjct: 695  GAQGPPGSAGPPGYPGPRGVKGTS-GNRGLQG-EKGEKGEDGFPGFKGDVGL-KGDQGKP 751

Query: 1327 TAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLP--------- 1377
             APG     G P G   +      G+     S GE  ++ V G+    G P         
Sbjct: 752  GAPGPRGEDG-PEGP--KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808

Query: 1378 --------SGEVVETSASGIEDVSELPS--GEGLETSASGVEDLSRLPSGEEVLEISASG 1427
                     G+  +T   G+E     P   GE  +  A+G       P G +V +  A G
Sbjct: 809  GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG----PKG-DVGQDGAPG 863

Query: 1428 FGDLSGLPS-----GGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDL 1482
                 GLP      G  G +      G D  G P G  G +    G +  +G P G   +
Sbjct: 864  IPGEKGLPGLQGPPGFPGPKGPPGHQGKD--GRP-GHPG-QRGELGFQGQTG-PPGPAGV 918

Query: 1483 VGSASGDLDLGKL-PSGTLGSGQAPETSGLP-----SGFSGEYSGV-DLGSGPPSGLPDF 1535
            +G      ++G L   G  G    P   GLP      G  GE      LG   P+GL  F
Sbjct: 919  LGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978

Query: 1536 SGLPSGFP----TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGR 1591
             G P G P       L           +  S  E RG +G +G   + G   SE  +   
Sbjct: 979  PG-PKGGPGDPGPTGLKGDKGPPGPVGANGSPGE-RGPLGPAGGIGLPGQSGSEGPVG-- 1034

Query: 1592 ASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGVTELSGLS---- 1645
                P+G + S    G P  +G+  IPG  G  G P G    SGE     ++        
Sbjct: 1035 ----PAGKKGSRGERGPPGPTGKDGIPGPLGPLG-PPGAAGPSGEEGDKGDVGAPGHKGS 1089

Query: 1646 ---------SGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQ--PSGLPGFSGA 1694
                      GQPGI G A     G   P G     G   G P L GQ    G+ GF G 
Sbjct: 1090 KGDKGDAGPPGQPGIRGPA-----GHPGPPGADGAQGR-RGPPGLFGQKGDDGVRGFVGV 1143

Query: 1695 TSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGK 1754
                P  + G     GE   +  V +     AP     +   GS    GLP G     G+
Sbjct: 1144 IG--PPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG----VGQ 1197

Query: 1755 SGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTP 1814
             G V   G+     D        P   G+P    ++  +      G++ P G     G  
Sbjct: 1198 PGAVGEKGERGDAGDPG-----PPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGED 1252

Query: 1815 SSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQ 1874
             +  +V              PT      GP G   +SG   G+P   G+     D+ G  
Sbjct: 1253 GAKGSV-------------GPTGLPGDLGPPGDPGVSGI-DGSPGEKGDPG---DVGG-- 1293

Query: 1875 SGLIEPSGEP--PGTP 1888
             G    SGEP  PG P
Sbjct: 1294 PGPPGASGEPGAPGPP 1309


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score =  119 bits (299), Expect = 3e-26
 Identities = 363/1626 (22%), Positives = 549/1626 (33%), Gaps = 253/1626 (15%)

Query: 692  TSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGT 751
            T+    EE  V+   PG         TT  PS   T++  F  EP+       +   + T
Sbjct: 137  TNSGHSEESTVSHSGPGATG------TTLFPSHSATSV--FVGEPKTSPITSAS---MET 185

Query: 752  SPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRP 811
            + LPG   T       +E+ST   S+   P  +  P+ +     SE+ + S       RP
Sbjct: 186  TALPGSTTT----AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHS-----RP 236

Query: 812  FPSVEL-FPSEEPFP--SKEPSPSEE-PSASEEPYTPSPPVPSWTELPSSGEESGAPDVS 867
             P+  + FP     P  S+E + S   P +++   +P    PS     S G ES     S
Sbjct: 237  GPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPS-----SLGPESTTFHSS 291

Query: 868  GDFTGSGDVSGHLDFSGQLSGDR----ASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDE 923
              +T +  +  +   SG L        ++G P   L  +  T+  G     +S       
Sbjct: 292  PGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQS------- 344

Query: 924  ERIEWPSTPTVGELPSG--AEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEV 981
                WPS+      PSG  +  ++ S +     S  P+     +S               
Sbjct: 345  ----WPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASS--------------- 385

Query: 982  LETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTA----PGVEDISGLPSGE 1037
              TT    E+ + + S  V   T P         SG V E+TA    PG       P   
Sbjct: 386  --TTLGHSEESTPVHSSPVATATTP--PPARSATSGHVEESTAYHRSPGSTQTMHFPES- 440

Query: 1038 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLE 1097
               +T  G  + S    G    T        S  PS     TTA           G    
Sbjct: 441  ---STTSGHSEESATFHGSTTHTK-------SSTPS-----TTAALAHTSYHSSLGSTET 485

Query: 1098 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1157
            T       ISG         ++P     + LP+G    +   G    S + SG +  TA 
Sbjct: 486  THFRDSSTISGRSEESKASHSSPDAMATTVLPAGST-PSVLVGDSTPSPISSGSMETTAL 544

Query: 1158 PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1217
            PG     GL        ++P   D + LP+  +  +        S    G    TA PG 
Sbjct: 545  PGSTTKPGLSEKSTTFYSSPRSPDTTHLPAS-MTSSGVSEESTTSHSRPGSTHTTAFPGS 603

Query: 1218 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1277
              + GL        ++PG  D +  P      +  P        P G    T  P     
Sbjct: 604  TTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP-GSTETTLLPDNTTA 662

Query: 1278 SGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDE-ISGLPSGEVLETTAPGVEEISG 1336
            SGL    +   ++      +  P+G    TT  G        PS        P       
Sbjct: 663  SGLLEASMPVHSSTRSPHTTLSPAGS---TTRQGESTTFHSWPSSNDTRPAPPTT----- 714

Query: 1337 LPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELP 1396
              +   +E ST++ G  S +P+        +S     SGL        S+ G       P
Sbjct: 715  --TSAFVEPSTTSHGSPSSIPT------THISARSTTSGLVEESTTYHSSPGSTQTMHFP 766

Query: 1397 SGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLP 1456
              +   TS  G E  +   S    +  + S    L   P+       S +      S   
Sbjct: 767  ESD--TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 824

Query: 1457 SGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFS 1516
            SGR     ++  ++D +G       L   ++  + LG+  +  + SG   ET+ LP    
Sbjct: 825  SGRSEESIASHSSQDATGTIV----LPARSTNSVLLGESTTSPISSGSM-ETTALP---- 875

Query: 1517 GEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAG 1576
                    GS    GL + S      P      +TL    T S+    E   +    G+ 
Sbjct: 876  --------GSTTTPGLSERSTTFHSSPRSPA--TTLSPASTTSSGVSEESTTSHSRPGST 925

Query: 1577 EISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETS 1636
              +  P S         GL   +  S  + GS D +  +P     +    G P TS  +S
Sbjct: 926  HTTAFPDSTT-----TPGLSRHSTTSHSSPGSTDTT-LLPA--STTTXLVGEPTTSPISS 977

Query: 1637 GVTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG-- 1690
            G TE + L  S+   G+S E S   Y +  S    ++  S  +SGV + S      PG  
Sbjct: 978  GSTETTALPGSTTTAGLS-EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1036

Query: 1691 ----FSGATSGVPDLVSGTTSGSGESSGITFVD---TSLVEVAPTTFKEEEGLGSVELSG 1743
                F G+T+        T S S   S  T +    T+   + P +     G GS E + 
Sbjct: 1037 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTL 1096

Query: 1744 LPSGEADLSGKSGMVDVS-------GQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSR 1796
            LP    D +  SG+++ S       G    T+  +G T++  E +   S  +      + 
Sbjct: 1097 LP----DNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1152

Query: 1797 AEIGSSLPSGAYYGSGTPSSFPTVSLV----------DRTLVESVTQAP--TAQEAGEGP 1844
                S+    +    G+PSS PT              + T V S   AP  T   A    
Sbjct: 1153 PTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTT 1212

Query: 1845 SGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGES 1904
            SG++E S A+  +P  S +   F + S       E       T +      STT+   E 
Sbjct: 1213 SGLVEESTAYHSSPG-STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 1271

Query: 1905 SVAMGTSGEASGLPEVTLITSEFVEGVT------EPTISQELGQRPPVTHTPQLFESSGK 1958
              +  +S  +       + T+ F E  T      E T S        +T  P  F +SG+
Sbjct: 1272 PTSYHSSPGS-------IATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGR 1324

Query: 1959 V--STAGDIS--------GATPVLPG-------------------SGVEVSSVPESSSET 1989
            +  ST   IS         +T   PG                   S   ++S   S   T
Sbjct: 1325 IAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPT 1384

Query: 1990 SAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSG-STLTFQEGEAS 2048
            S Y +A    + A  AS   SG   LS+ ++ FH       + L     +T +F +   +
Sbjct: 1385 SLYSQAESTHTTAFPASTTTSG---LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTT 1441

Query: 2049 AAPEVSGESTTTSDVGTEAPGLPSATPT--ASGDRTEISGDLSGHTSQLGVVISTSIPES 2106
               +     +T S   T  PGL   + T  +S   TE +     +T  +    ST  P+S
Sbjct: 1442 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDS 1501

Query: 2107 EWTQQTQRPAE---THLEIESSSLLYSGEETHTV---------ETATSPTDASIPASPEW 2154
                 T  PA    T +  ES++   S + T T          +    PT   I  SP +
Sbjct: 1502 PGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTY 1561

Query: 2155 KR---ESESTAAAPARSC----------------AEEPCGAGTCKETE--GHVICLCPPG 2193
                  S ST+     S                 + E    G C+E +      C+CP G
Sbjct: 1562 TTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQG 1621

Query: 2194 YTGEHC 2199
            Y G  C
Sbjct: 1622 YVGYQC 1627



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 130/538 (24%), Positives = 193/538 (35%), Gaps = 66/538 (12%)

Query: 1632 SGETSGVTELSGLSSGQPGISG-------EASGVLYGTSQPFGITDLSGETSGVPDLSGQ 1684
            S   SG +E S +S   PG +G        A+ V  G  +   IT  S ET+ +P  S  
Sbjct: 135  SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPG-STT 193

Query: 1685 PSGLPG-----FSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPT---TFKEEEGL 1736
             +GL       +S   S    L    T+ SG S   T   TS     PT    F +    
Sbjct: 194  TAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKST---TSHSRPGPTHTIAFPD---- 246

Query: 1737 GSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSR 1796
             S  + G+           G  D +    GT   S    ++  F   P       G +  
Sbjct: 247  -STTMPGVSQESTASHSIPGSTDTTLS-PGTTTPSSLGPESTTFHSSP-------GYTKT 297

Query: 1797 AEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHS 1855
              +  +  +     + TP    T S          T +P +    EG P+       +  
Sbjct: 298  TRLPDNTTTSGLLEASTPVHSSTGS-------PHTTLSPASSTTHEGEPTTFQSWPSSKD 350

Query: 1856 GAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEAS 1915
             +P  SG  S F+ LS        PS  P  T +FS   +STT    E S  + +S  A+
Sbjct: 351  TSPAPSGTTSAFVKLSTTYHS--SPSSTP--TTHFSA--SSTTLGHSEESTPVHSSPVAT 404

Query: 1916 GL--PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLP 1973
                P     TS  VE   E T            H P+   +SG    +    G+T    
Sbjct: 405  ATTPPPARSATSGHVE---ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK 461

Query: 1974 GSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGL 2033
             S     S   + + TS +   G   S      R+ S     SE + A H +    ++ +
Sbjct: 462  SS---TPSTTAALAHTSYHSSLG---STETTHFRDSSTISGRSEESKASHSSPDAMATTV 515

Query: 2034 GVSGSTLTFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGDRTEISGDLSGHT 2092
              +GST +   G+++ +P  SG   TT+  G T  PGL   + T        S   S  T
Sbjct: 516  LPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF------YSSPRSPDT 569

Query: 2093 SQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSG--EETHTVETATSPTDASI 2148
            + L   +++S    E T    RP  TH      S    G  +E+    ++  PTD ++
Sbjct: 570  THLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL 627



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 43/165 (26%), Positives = 68/165 (41%), Gaps = 20/165 (12%)

Query: 1994 EAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLG----VSGSTLTFQEG---E 2046
            E    A A  +  +E S SPD+SE T+  HE  +   S       ++GST+    G    
Sbjct: 40   EQARAAGAREKERQEVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTT 99

Query: 2047 ASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPES 2106
            +++ P  S   TT SD G     +  +T T        S   SGH+ +    +S S P +
Sbjct: 100  SASTPSSSDPFTTFSDYGVSVTFITGSTAT---KHFLDSSTNSGHSEE--STVSHSGPGA 154

Query: 2107 EWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPAS 2151
              T        T     S++ ++ GE   +  T+ S    ++P S
Sbjct: 155  TGT--------TLFPSHSATSVFVGEPKTSPITSASMETTALPGS 191


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  119 bits (297), Expect = 5e-26
 Identities = 380/1641 (23%), Positives = 557/1641 (33%), Gaps = 196/1641 (11%)

Query: 627  LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQT---GLPDPLSRHHAFCFRGISAVPSP 683
            L+ GS     + P        PG     L P+ T   GL +  +  H+      + +   
Sbjct: 1761 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 1820

Query: 684  GE--EEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTE 741
            G    +G + T  S           P   +  VE  TT+  S  +T    F+        
Sbjct: 1821 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 1880

Query: 742  WEPAYT----PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSE 797
             E + T    PV T+  P   P    T    EEST   S+         P  S     SE
Sbjct: 1881 SEESTTVHSSPVATATTPS--PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE 1938

Query: 798  EPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSS 857
            E   S          P           PS   +  EEP++    Y  SP   + T  P S
Sbjct: 1939 ESRTSHSSTTHTISSP-----------PSTTSALVEEPTS----YHSSPGSTATTHFPDS 1983

Query: 858  GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESG 917
               SG  + S     S D +G +    + +     G  +    SSG   T  + LP  + 
Sbjct: 1984 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET--TALPGSTT 2041

Query: 918  LPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGL 976
             P   E+   + S+P +     S A       S     S    G    T+        GL
Sbjct: 2042 TPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGL 2101

Query: 977  PSGEVLETTAPGVEDISGLP-----SGEVLETT----APGVEDISGLPSGEVL-----ET 1022
                    ++PG  D + LP     SG   E+T    +PG  D +  P          E+
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQES 2161

Query: 1023 T----APGVEDISGLPSGEVLETTAPGVEDISGL---PSGEVLETTAPGVEDISGLPSGE 1075
            T    +PG    +  P      TT+ G+ + S      +G    T +P      GL    
Sbjct: 2162 TTFHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 2217

Query: 1076 VLETTAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEV 1133
                T P     +  P      TA   VE+ +      G    T  P     SG      
Sbjct: 2218 TAFQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2273

Query: 1134 LETAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1192
            +  ++P   D SG  PS     T+  G    S +  G    T  PG     GL       
Sbjct: 2274 IFHSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2330

Query: 1193 TAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-GEVLETAAPGVEDISGLPS-GEVLET 1250
             ++P     +  P+   + +   G E  +     G    T +P      GL      + +
Sbjct: 2331 YSSPRSPTTTLSPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 2388

Query: 1251 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTA- 1309
            ++PG  + +  P      T+  G E  +         TT    +  +   SG   E+TA 
Sbjct: 2389 SSPGSTETTVFPRTPT--TSVRGEEPTTFHSRPASTHTTLFTEDSTT---SGLTEESTAF 2443

Query: 1310 PG--VDEISGLPSGEVLETTAPGVEEISGLPS--GEVLETSTSAVGDLSGLPSGGEVLEI 1365
            PG      +GLP+     TTA   EE +  PS  G    T + A    SGL        +
Sbjct: 2444 PGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL 2500

Query: 1366 SVSGVED--ISGLPSGEVVETSASGIEDVSELPSG--EGLETSASGVEDLSRLPSGEEVL 1421
            S S  E   + G P+   +   ++        P        T++SGV + S   S  +  
Sbjct: 2501 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-SHSQPG 2559

Query: 1422 EISASGFGDLSGLPSGGEGLETSASEVG-TDLSGLPSGREGLETSASGAEDLSGLPSGKE 1480
                + F D +  P       TS S  G TD + LP+      T+ SG       PS + 
Sbjct: 2560 STHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS-----TTTSG-------PSQES 2607

Query: 1481 DLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGL-- 1538
                S+ G  D    P  T       E++   S     ++ +   S   SG+ + S    
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVH 2667

Query: 1539 -PSGFP--TVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASG- 1594
              +G P  T+S   ST   +   ST  +     T         +  P  E     R+ G 
Sbjct: 2668 SSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 2727

Query: 1595 -----LPSGTELSGQAS------GSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSG 1643
                  P+ +  SG +        SPD SG  P     +    G   TS  + G TE++ 
Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787

Query: 1644 L--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG-----FSGA 1694
            L  S+  PG+S EAS   Y +  S    ++  S  + GV + S      PG      S A
Sbjct: 2788 LPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846

Query: 1695 TSGVPDLVSGTTSGSGESSGIT-------FVDTSLVEVAPTTFKEEEGLGSVEL------ 1741
            ++  P L   +T+    S G T          TS+    PTTF          L      
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST 2906

Query: 1742 -SGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-PEFSGLPSGIAEVSGESSRAEI 1799
             SGL        G           + T    G  S T P  SG        +  ++   +
Sbjct: 2907 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV 2966

Query: 1800 GSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQ-------APTAQEAGEGP-----SGI 1847
            G S PS       +PSS  T +L       S+++       +P + +A   P     SG+
Sbjct: 2967 GESTPSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021

Query: 1848 LELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVA 1907
             E S      P  +  H+     S   SGL   S EP  +    G   +T +    ++ +
Sbjct: 3022 SEESSTSHSQPGST--HTTAFPDSTTTSGL---SQEPTASHSSQGSTEATLSPGSTTASS 3076

Query: 1908 MG----TSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAG 1963
            +G    T   + G  E TL+  +        TI+  L +    TH+     S+G + T  
Sbjct: 3077 LGQQSTTFHSSPGDTETTLLPDD--------TITSGLVEASTPTHS-----STGSLHTTL 3123

Query: 1964 DISGATPV-LPGSGVEVSSVPESSSETSAYPEAGFGASAAP-EASREDSGSPDLSETT-- 2019
              + +T   L        S P SS  T + P    G +AAP E S      P  + TT  
Sbjct: 3124 TPASSTSAGLQEESTTFQSWPSSSDTTPSPP----GTTAAPVEVSTTYHSRPSSTPTTHF 3179

Query: 2020 --SAFHEANLERSSGLGVS-GSTLTFQEGEASAAPEVSGESTTT--SDVGTEAPGLPSAT 2074
              S+      E S+ +  S G+T T      SA   + GE TT+  S   TE   LP +T
Sbjct: 3180 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 3239

Query: 2075 PTAS---GDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSG 2131
             TA       T  S   S  T+      ++S    E T    RP  TH      S    G
Sbjct: 3240 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 3299

Query: 2132 EETHTVETATSPTDASIPASP 2152
                +  + +SP       SP
Sbjct: 3300 VSQESTASHSSPGSTDTTLSP 3320



 Score =  116 bits (290), Expect = 3e-25
 Identities = 374/1601 (23%), Positives = 530/1601 (33%), Gaps = 248/1601 (15%)

Query: 678  SAVPSPGEEEGGTPTSPSGVEEWIVTQ----------VVPGVAAVP-VEEETTA---VPS 723
            S+  SP        T+ SGV E   T             P    +P V +E+TA   +P 
Sbjct: 285  SSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPG 344

Query: 724  GETTAILEFTTEP-----ENQT-EWEPAYTPVGTSPLPGILPTWPPTGAAT--EESTEGP 775
               T +   TT P     E+ T    P YT   T+ LP    T     A+T    ST  P
Sbjct: 345  STDTTLSPGTTTPSSLGPESTTFHSSPGYTK--TTRLPDNTTTSGLLEASTPVHSSTGSP 402

Query: 776  SATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEP 835
              T  PS+S         F S   S    P PS      V+L  +    PS  P+     
Sbjct: 403  HTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA 462

Query: 836  SA-----SEE--PYTPSPPVPSWTELPSSGEESGAPDVSG------------DFTGSGDV 876
            S+     SEE  P   SP   + T  P+    SG  + S              F  S   
Sbjct: 463  SSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTT 522

Query: 877  SGHLDFSGQLSGDRA---SGLPS--GDLDSSGLTSTVGSGLPV---ESGLPSGDEERIE- 927
            SGH + S    G      S  PS    L  +   S++GS       +S   SG  E  + 
Sbjct: 523  SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582

Query: 928  ---WPSTPTVGELPSGA--EILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVL 982
                P       LP+G+   +L G ++     S + SG +  T+  G     GL      
Sbjct: 583  SHSSPDAMATTVLPAGSTPSVLVGDSTP----SPISSGSMETTALPGSTTKPGLSEKSTT 638

Query: 983  ETTAPGVEDISGLPSGEVLETTAPGVED---ISGLPSGEVLETTAPGVEDISGLPSGEVL 1039
              ++P   D + LP+      T+ GV +    S    G    T  PG   + GL      
Sbjct: 639  FYSSPRSPDTTHLPA----SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 694

Query: 1040 ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETA 1099
              ++PG  D +  P      +  P        P G    T  P     SGL    +   +
Sbjct: 695  SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP-GSTETTLLPDNTTASGLLEASMPVHS 753

Query: 1100 APGVEDISGLPSGEVLETAA-------PGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1152
            +      +  P+G              P  +D    P         P      G PS  +
Sbjct: 754  STRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTS-HGSPS-SI 811

Query: 1153 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1212
              T        SGL        ++PG       P  +   T+  G E  +   S     +
Sbjct: 812  PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT--TSGRGEESTTSHSSTTHTIS 869

Query: 1213 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL------ETAAPGVEDISG---LPS 1263
            +AP     S L        ++PG    +  P            TA+   +D +G   LP+
Sbjct: 870  SAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 927

Query: 1264 GEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEV 1323
                     G    S + SG +  T  PG     GL        ++P     +  P+   
Sbjct: 928  RSTTSVLL-GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPA--- 983

Query: 1324 LETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVE 1383
              TT+ GV E S         T T+A  D +  P                 GL       
Sbjct: 984  -STTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP-----------------GLSRHSTTS 1025

Query: 1384 TSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLET 1443
             S+ G  D + LP+     T+ SG       PS E     S+SG  D +  P       T
Sbjct: 1026 HSSPGSTDTTLLPA----STTTSG-------PSQESTTSHSSSGSTDTALSPG-----ST 1069

Query: 1444 SASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSG 1503
            +A   G + +   S      T+       S         V S++G       P  TL   
Sbjct: 1070 TALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS------PRTTL--- 1120

Query: 1504 QAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASE 1563
             +P +S  P G  GE +              F   P+   T     ST    V  ST   
Sbjct: 1121 -SPASSTSP-GLQGESTA-------------FQTHPASTHTTPSPPSTATAPVEESTTYH 1165

Query: 1564 LEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSG 1623
                 T            P++    S   SG    +E S     SPD SG  P     + 
Sbjct: 1166 RSPGST------------PTTHFPASSTTSG---HSEKSTIFHSSPDASGTTPSSAHSTT 1210

Query: 1624 QPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVP 1679
               G   TS  + G TE++ L  S+  PG+S EAS   Y +  S    ++  S  + GV 
Sbjct: 1211 SGRGESTTSRISPGSTEITTLPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVG 1269

Query: 1680 DLSGQPSGLPG-----FSGATSGVPDLVSGTTSGSGESSGIT-------FVDTSLVEVAP 1727
            + S      PG      S A++  P L   +T+    S G T          TS+    P
Sbjct: 1270 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP 1329

Query: 1728 TTFKEEEGLGSVEL-------SGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-PE 1779
            TTF          L       SGL        G           + T    G  S T P 
Sbjct: 1330 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389

Query: 1780 FSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQ------ 1833
             SG        +  ++   +G S PS       +PSS  T +L       S+++      
Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFY 1444

Query: 1834 -APTAQEAGEGP-----SGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887
             +P + +A   P     SG+ E S      P     H+     S   S L   S EP  +
Sbjct: 1445 TSPRSPDATLSPATTTSSGVSEESSTSHSQP--GSTHTTAFPDSTTTSDL---SQEPTTS 1499

Query: 1888 PYFSGDFASTTNVSGESSVAMG----TSGEASGLPEVTLITSEFVEGVTEPTISQELGQR 1943
                G   +T +    ++ ++G    T   + G  E TL+  +        TI+  L + 
Sbjct: 1500 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD--------TITSGLVEA 1551

Query: 1944 PPVTHTPQLFESSGKV-STAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAA 2002
               TH+     S+G + +T    S  +  L        S P SS  T + P    G +AA
Sbjct: 1552 STPTHS-----STGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPP----GTTAA 1602

Query: 2003 P-EASREDSGSPDLSETT----SAFHEANLERSSGLGVS-GSTLTFQEGEASAAPEVSGE 2056
            P E S      P  + TT    S+      E S+ +  S G+T T      SA   + GE
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662

Query: 2057 STTT--SDVGTEAPGLPSATPTA---SGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQ 2111
             TT+  S   TE   LP +T TA       T  S   S  T+      ++S    E T  
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1722

Query: 2112 TQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASP 2152
              RP  TH      S    G    +  + +SP       SP
Sbjct: 1723 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1763



 Score =  115 bits (287), Expect = 7e-25
 Identities = 358/1588 (22%), Positives = 541/1588 (34%), Gaps = 200/1588 (12%)

Query: 682  SPGEEEGGTPTSP----SGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPE 737
            S  +  G TP+S     SG  E   +++ PG   +     +T  P G + A   F + P 
Sbjct: 2751 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP-GLSEASTTFYSSPR 2809

Query: 738  NQTEWEPAYTPVGTSPLP-GILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPS 796
            + T      +P   + L  G   T   +   +  ST  P++T  P  SEE +       S
Sbjct: 2810 SPTT---TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY----S 2862

Query: 797  EEPSPSEEPFPSVRPFPSVELFPSEEP--FPSKEPSP-----SEEPSAS----EEPYTPS 845
              P  +E    +V P  +      EEP  F S+  S      +E+ + S    E    P 
Sbjct: 2863 SSPGSTET---TVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 2919

Query: 846  PPVPSWTELPSS------GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDL 899
             P  + T LP++      GEES     S   TG+         SG +     S L     
Sbjct: 2920 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2979

Query: 900  DSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959
            +++ L      G P    L          P +P     P+       ++SGV + S    
Sbjct: 2980 ETTTLP-----GSPTTPSLSEKSTTFYTSPRSPDATLSPATT-----TSSGVSEESSTSH 3029

Query: 960  GEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEV 1019
             +   T  +   D S   SG   E TA      S    G    T +PG    S L     
Sbjct: 3030 SQPGSTHTTAFPD-STTTSGLSQEPTA------SHSSQGSTEATLSPGSTTASSLGQQST 3082

Query: 1020 LETTAPGVEDISGLPSGEVLETTAPGVEDISG---LPSGEVLETTAPGVEDISGLPSGEV 1076
               ++PG  + + LP     +T   G+ + S      +G +  T  P     +GL     
Sbjct: 3083 TFHSSPGDTETTLLPD----DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 3138

Query: 1077 LETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS---GLPSGEV 1133
               + P   D +  P G    TAAP   ++S         T        S   G      
Sbjct: 3139 TFQSWPSSSDTTPSPPGT---TAAP--VEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 3193

Query: 1134 LETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1193
               ++PG    +  P+         G    S + SG    TA PG    +GL        
Sbjct: 3194 TVHSSPGATGTALFPTRSATSVLV-GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252

Query: 1194 AAPGVEDISGLPSGEVLETAAPGVEDISGLPS---GEVLETAAPGVEDISGLPSGEVLET 1250
            ++P   D +  P+     T + GV + S       G    TA PG   + G+        
Sbjct: 3253 SSPRSPDTTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH 3308

Query: 1251 AAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAP 1310
            ++PG  D +  P      +  P        P G    T  P     SGL        ++ 
Sbjct: 3309 SSPGSTDTTLSPGSTTASSLGPESTTFHSGP-GSTETTLLPDNTTASGLLEASTPVHSST 3367

Query: 1311 GVDEISGLPSGEVL---ETTA----PGVEEISGLPSGEVLETSTSAVGDLS----GLPSG 1359
            G    +  P+G      E+T     P  ++ +  P      T+TSA  +LS    G PS 
Sbjct: 3368 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPP-----TTTSAFVELSTTSHGSPSS 3422

Query: 1360 GEVLEISVSGV-----EDISGLPSGEVV---------ETSASGIEDVSELPSGEGLETSA 1405
                  S S       E+ + + S  V           T++  +E+ +   S  G   + 
Sbjct: 3423 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM 3482

Query: 1406 SGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGL--------ETSASEVGTDL--SGL 1455
               E  +    GEE     +S    +S  PS    L         +  S   T    S  
Sbjct: 3483 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 3542

Query: 1456 PSGREGLETSASGAEDLSG---LPS--------GKEDLVGSASGDLDLGKLPSGTLGSGQ 1504
             SGR    T++  ++D +G   LP+        G+      +SG ++   LP  T   G 
Sbjct: 3543 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 3602

Query: 1505 APETSGLPSGFSGEYSGVDLGSGPPSGLPDFS----GLPSGFPTVSLVDSTLVEVVTAST 1560
            + +++   S      + +   S   SG+ + S      P    T +  DST        T
Sbjct: 3603 SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDST--------T 3654

Query: 1561 ASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFG 1620
               L    T   S  G      ++ L  S   SG    +  S  +SGS D +        
Sbjct: 3655 TPGLSRHSTTSHSSPGSTD---TTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTA 3711

Query: 1621 VS-GQPSG-FPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGV 1678
            +S GQ S  F  + G T   T L   S+   GI   ++ V   T  P   T LS  +S  
Sbjct: 3712 LSFGQESTTFHSSPGSTH--TTLFPDSTTSSGIVEASTRVHSSTGSPR--TTLSPASSTS 3767

Query: 1679 PDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGS 1738
            P L G+ +       +T   P   S  T+   ES               TT+    G   
Sbjct: 3768 PGLQGESTAFQTHPASTHTTPSPPSTATAPVEES---------------TTYHRSPGSTP 3812

Query: 1739 VELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGE----- 1793
                   S  +  S KS +   S   SGT  SS  ++ +       S I+  S E     
Sbjct: 3813 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 3872

Query: 1794 SSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGA 1853
             S    G S  S  +Y S  P S PT +L   ++        +     +  S    +S A
Sbjct: 3873 GSTTTPGLSEASTTFYSS--PRS-PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929

Query: 1854 HSGAPDMSGEHSGFLDLS-GLQSGLIEPSG-------EPPGTPYFSGDFASTTNVSGESS 1905
             +  P +S E +     S G     + P         E P T + S   ++ T +  E S
Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEP-TTFHSRPASTHTTLFTEDS 3988

Query: 1906 VAMGTSGEASGLP----------EVTLITSEF-VEGVTEPTISQELGQR-PPVTHTPQLF 1953
               G + E++  P            TL T++   E  T P+ S   G +  P   T    
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 1954 ESSGKVSTAGDISGATPVLPGSGVEVSSVPESSS--ETSAYPEAGFGASAAPEASREDSG 2011
                  S     S  T  LPGS    S   +S++   +   P+A    +    +   +  
Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108

Query: 2012 SPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLP 2071
            S   S+  S    A  + ++  G+S    T    + S    +S  STT S +G ++    
Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168

Query: 2072 SA----TPTASGDRTEISGDLSGHT---SQLGVVISTSIPESEWTQQTQRPAETHLEIES 2124
            S+      T   D T  SG +   T   S  G + +T  P S  +   Q  + T     S
Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228

Query: 2125 SS-LLYSGEETHTVETATSPTDASIPAS 2151
            SS    S   T  V    S T  S P+S
Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSS 4256



 Score =  114 bits (286), Expect = 9e-25
 Identities = 350/1609 (21%), Positives = 528/1609 (32%), Gaps = 246/1609 (15%)

Query: 713  PVEEETTAVPSGETTA--ILEFTTEPENQTEWEPAYTPVGTSPL------------PG-- 756
            P   +TT +P+  TT+    E TT   +    + A +P  T+ L            PG  
Sbjct: 3669 PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGST 3728

Query: 757  ---ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFP 813
               + P    +    E ST   S+T  P  +  P+ S  P    E +  +    S    P
Sbjct: 3729 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP 3788

Query: 814  SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873
            S          PS   +P EE +     Y  SP     T  P+S   SG  + S  F  S
Sbjct: 3789 SP---------PSTATAPVEESTT----YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 3835

Query: 874  GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933
             D SG    S   +        +  +       T   G     GL          P +PT
Sbjct: 3836 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 3895

Query: 934  VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993
                P+              ++ L  GE   TS S  G      S     TT PG+ + S
Sbjct: 3896 TTLSPAS-------------MTSLGVGEESTTSRSQPGSTHSTVSPA--STTTPGLSEES 3940

Query: 994  GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053
                   + +++PG  + +  P      TT+   E+ +   S      T    ED +   
Sbjct: 3941 -----TTVYSSSPGSTETTVFPRST---TTSVRREEPTTFHSRPASTHTTLFTEDST--T 3990

Query: 1054 SGEVLETTA-PG--VEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETAAPGVEDISG 1108
            SG   E+TA PG      +GLP+     TTA   E+ +  PS  G      +P     SG
Sbjct: 3991 SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 4047

Query: 1109 LPSGEVLETAAPGVEDISGLPSGEVLET---------AAPGVEDISGLPSGEVLETAAPG 1159
            L         +P   + + LP      +          +P   D +  P+     T + G
Sbjct: 4048 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA----TTTSSG 4103

Query: 1160 VEDISGLPS---GEVLETAAPGVEDISGLPS---------GEVLETAAPGVEDISGLPSG 1207
            V + S       G    TA P     SGL           G    T +PG    S L   
Sbjct: 4104 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQ 4163

Query: 1208 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISG---LPSGEVLETAAPGVEDISGLPSG 1264
                 ++PG  + + LP     +T   G+ + S      +G +  T  P     +GL   
Sbjct: 4164 STTFHSSPGDTETTLLPD----DTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEE 4219

Query: 1265 EVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVL 1324
                 + P   D +  P      TTA  VE  +   S      T       + L   E  
Sbjct: 4220 STTFQSWPSSSDTTPSPPS----TTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 4275

Query: 1325 ET--TAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVV 1382
             T  ++PG        +G  L  + SA   L G P+   +     SG  + + LP     
Sbjct: 4276 TTVHSSPGA-------TGTALFPTRSATSVLVGEPTTSPIS----SGSTETTALPGS--- 4321

Query: 1383 ETSASGIEDVSEL--PSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEG 1440
             T+ +G+ + S     S    +T+ S     S   S E     S  G    +  PS    
Sbjct: 4322 -TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSS--- 4377

Query: 1441 LETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500
              T+   V  + +   S     +T+ S     +     +     S+ G  +   LP  T 
Sbjct: 4378 --TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 4435

Query: 1501 GSGQAPETSGLPSGFSGEYSGVD-LGSGPPSG-LPDFSGLPSGFPTVSLVDSTLVEVVTA 1558
             SG    ++ + S     ++ +   GS    G    F   P+   T     +T    V  
Sbjct: 4436 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 4495

Query: 1559 STASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGL 1618
            ST S             G  S  P++    S    G    +E S     SP  +   P  
Sbjct: 4496 STTSH------------GSPSSTPTTHFSASSTTLGR---SEESTTVHSSPVATATTPS- 4539

Query: 1619 FGVSGQPSGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGV 1678
                            TSG+ E S      PG +         T+   G    +  +S  
Sbjct: 4540 -----------PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTT 4588

Query: 1679 PDLSGQPS-------------GLPGFSGATSGVPDLVSGTTSGSGESSGITFV--DTSLV 1723
              +S  PS               PG S AT+  PD  S TTSG  E S  +    D +  
Sbjct: 4589 HTISSAPSTTSALVEEPTSYHSSPG-STATTHFPD--SSTTSGRSEESTASHSSQDATGT 4645

Query: 1724 EVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGL 1783
             V P        LG    S + SG  + +             G+  + G + ++  F   
Sbjct: 4646 IVLPARSTTSVLLGESTTSPISSGSMETTA----------LPGSTTTPGLSEKSTTFHSS 4695

Query: 1784 PSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG 1843
            PS        +S   +G S  S   + S  P +  T     R+    + +  TA  +  G
Sbjct: 4696 PSSTPTTHFSASSTTLGRSEESTTVHSS--PVATATTPSPARSTTSGLVEESTAYHSSPG 4753

Query: 1844 PSGIL---ELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNV 1900
             +  +   E S A   + +    HS                 E P T Y S   +  T  
Sbjct: 4754 STQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEP-TSYHSSPGSIATTH 4812

Query: 1901 SGESSVAMGTSGEASGLPEVTLITSEFVEGVTEP----TISQELGQRPPVTHTPQLFESS 1956
              ESS   G S E++        +S    G+T      T S  + +      +P   E++
Sbjct: 4813 FPESSTTSGRSEESTASH-----SSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 4867

Query: 1957 -GKVSTAGDISGATPVLPGSG---------VEVSSVPESSSETSAYPEAGFGASAAPEAS 2006
                +T   +S  + +L  S            ++S   S   TS Y +A    + A  AS
Sbjct: 4868 LASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAS 4927

Query: 2007 REDSGSPDLSETTSAFHEANLERSSGLGVSG-STLTFQEGEASAAPEVSGESTTTSDVGT 2065
               SG   LS+ ++ FH       + L     +T +F +   +   +     +T S   T
Sbjct: 4928 TTTSG---LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPAST 4984

Query: 2066 EAPGLPSATPT--ASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAE---THL 2120
              PGL   + T  +S   TE +     +T  +    ST  P+S     T  PA    T +
Sbjct: 4985 TVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDI 5044

Query: 2121 EIESSSLLYSGEETHTV---------ETATSPTDASIPASPEWKR---ESESTAAAPARS 2168
              ES++   S + T T          +    PT   I  SP +      S ST+     S
Sbjct: 5045 GQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEES 5104

Query: 2169 C----------------AEEPCGAGTCKETE--GHVICLCPPGYTGEHC 2199
                             + E    G C+E +      C+CP GY G  C
Sbjct: 5105 TTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVCPQGYVGYQC 5153



 Score =  112 bits (280), Expect = 4e-24
 Identities = 353/1560 (22%), Positives = 524/1560 (33%), Gaps = 248/1560 (15%)

Query: 713  PVEEETTAVPSGETTA--ILEFTTEPENQTEWEPAYTPVGTSPL------------PG-- 756
            P   +TT +P+  TT+    E TT   +    + A +P  T+ L            PG  
Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2171

Query: 757  ---ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFP 813
               + P    +    E ST   S+T  P  +  P+ S  P    E +  +    S    P
Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP 2231

Query: 814  SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873
            S          PS   +P EE +     Y  SP     T  P+S   SG  + S  F  S
Sbjct: 2232 SP---------PSTATAPVEESTT----YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS 2278

Query: 874  GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933
             D SG    S   +        +  +       T   G     GL          P +PT
Sbjct: 2279 PDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 2338

Query: 934  VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993
                P+              ++ L  GE   TS S  G      S     TT PG+ + S
Sbjct: 2339 TTLSPAS-------------MTSLGVGEESTTSRSQPGSTHSTVSPA--STTTPGLSEES 2383

Query: 994  GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053
                   + +++PG  + +  P      TT+   E+ +   S      T    ED +   
Sbjct: 2384 -----TTVYSSSPGSTETTVFPR---TPTTSVRGEEPTTFHSRPASTHTTLFTEDST--T 2433

Query: 1054 SGEVLETTA-PG--VEDISGLPSGEVLETTAPGVEDISGLPS--GEVLETAAPGVEDISG 1108
            SG   E+TA PG      +GLP+     TTA   E+ +  PS  G    T +P     SG
Sbjct: 2434 SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490

Query: 1109 LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS 1168
            L         +P   + + LP      + +         P      T +P     SG+  
Sbjct: 2491 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA-TLSPATTTSSGVSE 2549

Query: 1169 GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEV 1228
                  + PG    +  P      T  PG+   S          ++PG  D + LP+   
Sbjct: 2550 ESSTSHSQPGSTHTTAFPDS----TTTPGLSRHS------TTSHSSPGSTDTTLLPASTT 2599

Query: 1229 LETAAPGVEDISGLPSGEVLETA-APGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE 1287
              T+ P  E  +   S    +TA +PG               ++PG    +  P      
Sbjct: 2600 --TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---- 2653

Query: 1288 TTAPGVEEISGL---PSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEV-- 1342
            TT+ G+ E S      +G    T +P      GL        T P     +  P      
Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATA 2713

Query: 1343 -LETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGL 1401
             +E ST+        P+       + SG  + S +         ASG       PS    
Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSS---PDASGTT-----PSSAHS 2765

Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLS--GLPSGR 1459
             TS  G    SR+  G   +  +  G     GL        +S     T LS   + S  
Sbjct: 2766 TTSGRGESTTSRISPGSTEIT-TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2824

Query: 1460 EGLETSASGAEDLS-------------GLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAP 1506
             G E++ S ++  S             GL      +  S+ G  +    P  T  S +  
Sbjct: 2825 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGE 2884

Query: 1507 ETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEG 1566
            E +   S  +  ++ +       SGL + S    G P      ST   +    T ++L  
Sbjct: 2885 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA-----STQTGLPATLTTADLGE 2939

Query: 1567 RGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPS 1626
              T   S +G      S     +    G  + + LS  ++ +  + G  P    +S + +
Sbjct: 2940 ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS-PTTPSLSEKST 2998

Query: 1627 GF------PDTS-----GETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGET 1675
             F      PD +       +SGV+E S  S  QPG +       + T+ P   T     T
Sbjct: 2999 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGST-------HTTAFPDSTT-----T 3046

Query: 1676 SGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEG 1735
            SG   LS +P+      G+T       S T S  G+ S              TTF    G
Sbjct: 3047 SG---LSQEPTASHSSQGSTEATLSPGSTTASSLGQQS--------------TTFHSSPG 3089

Query: 1736 LGSVELSGLPSGEADLSGKSGMVDVS-------GQFSGTVD-----SSGFTSQTPEFSGL 1783
                E + LP    D +  SG+V+ S       G    T+      S+G   ++  F   
Sbjct: 3090 --DTETTLLP----DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 3143

Query: 1784 PSGIAEVSGESSRAEIGSSLP----SGAYYGSGTPSSFPTV--SLVDRTLVESVTQAPTA 1837
            PS     S +++ +  G++      S  Y+    PSS PT   S    TL  S       
Sbjct: 3144 PS-----SSDTTPSPPGTTAAPVEVSTTYHSR--PSSTPTTHFSASSTTLGRSEESTTVH 3196

Query: 1838 QEAGEGPSGILELSGAHS---GAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDF 1894
               G   + +     A S   G P  S   SG  + + L             T ++S   
Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 3256

Query: 1895 ASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFE 1954
            +  T +S  S+ + G S E++        TS    G T  T        P V+      E
Sbjct: 3257 SPDTTLSPASTTSSGVSEEST--------TSHSRPGSTHTTAFPGSTTMPGVSQ-----E 3303

Query: 1955 SSGKVSTAGDISGATPVLPGSGVEVSSVPES--------SSETSAYPEAGFGASAAPEAS 2006
            S+   S+ G  S  T + PGS    S  PES        S+ET+  P+    AS   EAS
Sbjct: 3304 STASHSSPG--STDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPD-NTTASGLLEAS 3360

Query: 2007 REDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTS--DVG 2064
                 S     TT       L  +      G + TFQ    S     +  +TT++  ++ 
Sbjct: 3361 TPVHSSTGSPHTT-------LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 3413

Query: 2065 TEAPGLPSATPTA--SGDRTEISGDLSGHTSQLGVVISTSIPE----------SEWTQQT 2112
            T + G PS+TPT   S   T +       T     V + + P            E T   
Sbjct: 3414 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYH 3473

Query: 2113 QRPAETHLEI--ESSSLLYSGEE--------THTVETATSPTDASIPASPEWKRESESTA 2162
              P  T      ES +    GEE        THT+ +A S T A +     +     STA
Sbjct: 3474 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTA 3533



 Score =  108 bits (271), Expect = 5e-23
 Identities = 361/1554 (23%), Positives = 535/1554 (34%), Gaps = 216/1554 (13%)

Query: 682  SPGEEEGGTPTSP----SGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPE 737
            S  +  G TP+S     SG  E   +++ PG   +     +T  P G + A   F + P 
Sbjct: 2277 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP-GLSEASTTFYSSPR 2335

Query: 738  NQTEWEPAYTPVGTSPLP-GILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPS 796
            + T      +P   + L  G   T   +   +  ST  P++T  P  SEE   S   + S
Sbjct: 2336 SPTT---TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE---STTVYSS 2389

Query: 797  EEPSPSEEPFPSVRPFPSVELFPSEEP--FPSKEPSP-----SEEPSAS----EEPYTPS 845
               S     FP   P  SV     EEP  F S+  S      +E+ + S    E    P 
Sbjct: 2390 SPGSTETTVFPRT-PTTSVR---GEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG 2445

Query: 846  PPVPSWTELPSS------GEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDL 899
             P  + T LP++      GEES     S   TG+         SG +     S L     
Sbjct: 2446 SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2505

Query: 900  DSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPS 959
            +++ L      G P    L          P +P     P+       ++SGV + S    
Sbjct: 2506 ETTTLP-----GSPTTPSLSEKSTTFYTSPRSPDATLSPATT-----TSSGVSEESSTSH 2555

Query: 960  GEVLETSASGVGDLSGLPSGEVLETTA---PGVEDISGLP-----SGEVLETT----APG 1007
             +   T  +   D +  P      TT+   PG  D + LP     SG   E+T    +PG
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615

Query: 1008 VEDISGLPSGEVL-----ETT----APGVEDISGLPSGEVLETTAPGVEDISGL---PSG 1055
              D +  P          E+T    +PG    +  P      TT+ G+ + S      +G
Sbjct: 2616 STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTG 2671

Query: 1056 EVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGE 1113
                T +P      GL        T P     +  P      TA   VE+ +      G 
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGS 2727

Query: 1114 VLETAAPGVEDISGLPSGEVLETAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVL 1172
               T  P     SG      +  ++P   D SG  PS     T+  G    S +  G   
Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTE 2784

Query: 1173 ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS-GEVLET 1231
             T  PG     GL        ++P     +  P+   + +   G E  +     G    T
Sbjct: 2785 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS--MTSLGVGEESTTSRSQPGSTHST 2842

Query: 1232 AAPGVEDISGLPS-GEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTA 1290
             +P      GL      + +++PG  + +  P      T+  G E  +         TT 
Sbjct: 2843 VSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTT--TSVRGEEPTTFHSRPASTHTTL 2900

Query: 1291 PGVEEISGLPSGEVLETTA-PG--VDEISGLPSGEVLETTAPGVEEISGLPS--GEVLET 1345
               +  +   SG   E+TA PG      +GLP+     TTA   EE +  PS  G    T
Sbjct: 2901 FTEDSTT---SGLTEESTAFPGSPASTQTGLPA---TLTTADLGEESTTFPSSSGSTGTT 2954

Query: 1346 STSAVGDLSGLPSGGEVLEISVSGVED--ISGLPSGEVVETSASGIEDVSELPSG--EGL 1401
             + A    SGL        +S S  E   + G P+   +   ++        P       
Sbjct: 2955 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 3014

Query: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREG 1461
             T++SGV +       E     S  G    +  P       T+ S +  + +   S +  
Sbjct: 3015 TTTSSGVSE-------ESSTSHSQPGSTHTTAFPDS-----TTTSGLSQEPTASHSSQGS 3062

Query: 1462 LETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSG 1521
             E + S     +     +     S+ GD +   LP  T+ SG    ++   S     ++ 
Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 3122

Query: 1522 VDLGSGPPSGLPD----FSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGE 1577
            +   S   +GL +    F   PS   T      T    V  ST        T     +  
Sbjct: 3123 LTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSAS 3182

Query: 1578 ISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSG 1637
             + L  SE   +  +S   +GT L    S +  + GE              P TS  +SG
Sbjct: 3183 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE--------------PTTSPISSG 3228

Query: 1638 VTELSGL--SSGQPGISGEASGVLYGT--SQPFGITDLSGETSGVPDLSGQPSGLPG--- 1690
             TE + L  S+   G+S E S   Y +  S    ++  S  +SGV + S      PG   
Sbjct: 3229 STETTALPGSTTTAGLS-EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH 3287

Query: 1691 ---FSGATSGVPDLVSGTTSGSGESSGITFVD---TSLVEVAPTTFKEEEGLGSVELSGL 1744
               F G+T+        T S S   S  T +    T+   + P +     G GS E + L
Sbjct: 3288 TTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLL 3347

Query: 1745 PSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLP 1804
            P    D +  SG+++ S     +  S       P  +  P+G     GES+  +   S P
Sbjct: 3348 P----DNTTASGLLEASTPVHSSTGS-------PHTTLSPAGSTTRQGESTTFQ---SWP 3393

Query: 1805 SGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQ-EAGEGPSGILELSGAHSGAPDMSGE 1863
            +        P++      +  T   S +  PT    A     G  E S     +P  +  
Sbjct: 3394 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 3453

Query: 1864 HSGFLDLSGLQSGLIEPS----GEPPGTPYFSGDFASTTNVSGESSVAM--GTSGEASGL 1917
                       SGL+E S      P  T       + TT+  GE S      T+   S  
Sbjct: 3454 TPS--PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 3511

Query: 1918 PEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKV--STAGDISG---ATPVL 1972
            P  T   S  VE   EPT           TH P    +SG+   STA   S     T VL
Sbjct: 3512 PSTT---SALVE---EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565

Query: 1973 PGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSG 2032
            P      +SV    S TS         +A P ++     +P LSE ++ FH +       
Sbjct: 3566 PARST--TSVLLGESTTSPISSGSMETTALPGSTT----TPGLSEKSTTFHSS------- 3612

Query: 2033 LGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAP---GLPSATPTASGDRTEISGDLS 2089
                           S A  +S  STT+S V  E+      P +T T +   +  +  LS
Sbjct: 3613 -------------PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 3659

Query: 2090 GHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSP 2143
             H++      S S P S  T  T  PA T     S     S   + + +TA SP
Sbjct: 3660 RHST-----TSHSSPGS--TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP 3706



 Score =  108 bits (270), Expect = 6e-23
 Identities = 353/1593 (22%), Positives = 525/1593 (32%), Gaps = 206/1593 (12%)

Query: 670  HAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAV-------------PVEE 716
            H   F G + +P   +E   + +SP   +    T + PG                 P   
Sbjct: 675  HTTAFPGSTTMPGLSQESTASHSSPGPTD----TTLSPGSTTASSLGPEYTTFHSRPGST 730

Query: 717  ETTAVPSGETTAILEFTTEPENQTEWEPAYT--PVGTSPLPGILPT---WPPTGAATEES 771
            ETT +P   T + L   + P + +   P  T  P G++   G   T   WP +       
Sbjct: 731  ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAP 790

Query: 772  TEGPSATEVPSASEEPSPSEVP-------------------FPSEEPSPSEEPFP----- 807
                SA   PS +   SPS +P                   + S   S     FP     
Sbjct: 791  PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 850

Query: 808  SVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVS 867
            S R   S     S     S  PS +         Y  SP   + T  P S   SG  + S
Sbjct: 851  SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 910

Query: 868  GDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIE 927
                 S D +G +    + +     G  +    SSG   T  + LP  +  P   E    
Sbjct: 911  TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET--TALPGSTTTPGLSERSTT 968

Query: 928  WPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTA 986
            + S+P +     S A       S     S    G    T+        GL        ++
Sbjct: 969  FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 1028

Query: 987  PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT-APGVEDISGLPSGEVLETTAPG 1045
            PG  D + LP+     T+ P  E  +   S    +T  +PG               + PG
Sbjct: 1029 PGSTDTTLLPASTT--TSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPG 1086

Query: 1046 VEDISGLPSGEVLETTAPGVEDISGL---PSGEVLETTAPGVEDISGLPSGEVLETAAPG 1102
                +  P      TT+ G+ + S      +G    T +P      GL          P 
Sbjct: 1087 STHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 1142

Query: 1103 VEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETAAPGV 1160
                +  P      TA   VE+ +      G    T  P     SG      +  ++P  
Sbjct: 1143 STHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP-- 1196

Query: 1161 EDISGL-PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVED 1219
             D SG  PS     T+  G    S +  G    T  PG     GL        ++P    
Sbjct: 1197 -DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT 1255

Query: 1220 ISGLPSGEVLETAAPGVEDISGLPS-GEVLETAAPGVEDISGLPS-GEVLETAAPGVEDI 1277
             +  P+   + +   G E  +     G    T +P      GL      + +++ G  + 
Sbjct: 1256 TTLSPAS--MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTET 1313

Query: 1278 SGLPSGEVLETTAPGVEEIS----------------GLPSGEVLETTA-PG--VDEISGL 1318
            +  P      T+  G E  +                   SG   E+TA PG      +GL
Sbjct: 1314 TVFPHSTT--TSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 1371

Query: 1319 PSGEVLETTAPGVEEISGLPS--GEVLETSTSAVGDLSGLPSGGEVLEISVSGVED--IS 1374
            P+     TTA   EE +  PS  G      + A    SGL        +S S  E   + 
Sbjct: 1372 PA---TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP 1428

Query: 1375 GLPSGEVVETSASGIEDVSELPSG--EGLETSASGVEDLSRLPSGEEVLEISASGFGDLS 1432
            G P+   +   ++        P        T++SGV +       E     S  G    +
Sbjct: 1429 GSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE-------ESSTSHSQPGSTHTT 1481

Query: 1433 GLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDL 1492
              P       T+ S++  + +   S +   E + S     +     +     S+ GD + 
Sbjct: 1482 AFPDS-----TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 1536

Query: 1493 GKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPD----FSGLPSGFPTVSLV 1548
              LP  T+ SG    ++   S     ++ +   S   +GL +    F   PS   T    
Sbjct: 1537 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1596

Query: 1549 DSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGS 1608
              T    V  ST        T     +   + L  SE   +  +S   +GT L    S +
Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT 1656

Query: 1609 PDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSGL--SSGQPGISGEASGVLYGT--SQ 1664
              + GE              P TS  +SG TE + L  S+   G+S E S   Y +  S 
Sbjct: 1657 SVLVGE--------------PTTSPISSGSTETTALPGSTTTAGLS-EKSTTFYSSPRSP 1701

Query: 1665 PFGITDLSGETSGVPDLSGQPSGLPG------FSGATSGVPDLVSGTTSGSGESSGITFV 1718
               ++  S  +SGV + S      PG      F G+T+        T S S   S  T +
Sbjct: 1702 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL 1761

Query: 1719 D---TSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTS 1775
                T+   + P +       GS E + LP    D +  SG+++ S     +  S     
Sbjct: 1762 SPGSTTASSLGPESTTFHSSPGSTETTLLP----DNTTASGLLEASTPVHSSTGS----- 1812

Query: 1776 QTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAP 1835
              P  +  P+G     GES+  +   S PS        P++      +  T   S +  P
Sbjct: 1813 --PHTTLSPAGSTTRQGESTTFQ---SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTP 1867

Query: 1836 TAQ-EAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDF 1894
            T    A     G  E S     +P  +             SGL+E S     T Y S   
Sbjct: 1868 TTHFSASSTTLGRSEESTTVHSSPVATATTPS--PARSTTSGLVEES-----TAYHSSPG 1920

Query: 1895 ASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFE 1954
            ++ T    ESS A G S E           S      T  TIS      PP T +  + E
Sbjct: 1921 STQTMHFPESSTASGRSEE-----------SRTSHSSTTHTISS-----PPSTTSALVEE 1964

Query: 1955 SSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPD 2014
             +   S+ G  S AT   P S        ES++  S+    G     A   +    G   
Sbjct: 1965 PTSYHSSPG--STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 2022

Query: 2015 LSETTSAFHEANLERSSGL--GVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEA----- 2067
             S  +S   E      S    G+S  + TF     S A  +S  STT+S V  E+     
Sbjct: 2023 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS 2082

Query: 2068 -PG------LPSATPTASGDR---TEISGDLSGHTSQLGVVISTSIPESEWTQQTQRP-- 2115
             PG       P +T T    R   T  S   S  T+ L    +TS P  E T     P  
Sbjct: 2083 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGS 2142

Query: 2116 AETHLEIESSSLLYSGEETHTVETATSPTDASI 2148
             +T L   S++ L  G+E+ T  ++   T  ++
Sbjct: 2143 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2175



 Score =  106 bits (264), Expect = 3e-22
 Identities = 358/1575 (22%), Positives = 521/1575 (33%), Gaps = 219/1575 (13%)

Query: 670  HAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAI 729
            H   F G + +P   +E   + +SP   +    T + PG         TTA   G     
Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHSSPGSTD----TTLSPG--------STTASSLGP---- 1773

Query: 730  LEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSP 789
             E TT   +    E    P  T+   G+L    P       ST  P  T  P+ S     
Sbjct: 1774 -ESTTFHSSPGSTETTLLPDNTTA-SGLLEASTPV----HSSTGSPHTTLSPAGSTTRQG 1827

Query: 790  SEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSA-----SEEPYT- 843
                F S   S    P P       VEL  +    PS  P+     S+     SEE  T 
Sbjct: 1828 ESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887

Query: 844  -PSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDS- 901
              SP   + T  P+    SG  + S  +  S   +  + F        ASG       S 
Sbjct: 1888 HSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP---ESSTASGRSEESRTSH 1944

Query: 902  SGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGE 961
            S  T T+ S     S L          P +      P                S   SG 
Sbjct: 1945 SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD---------------SSTTSGR 1989

Query: 962  VLETSASGVG-DLSGLPSGEVLETTAP--GVEDISGLPSGEVLETTAPGVEDISGLPSGE 1018
              E++AS    D +G        TT+   G    S + SG +  T  PG     GL    
Sbjct: 1990 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 2049

Query: 1019 VLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS---GEVLETTAPGVEDISGLPSGE 1075
                ++P     +  P+     TT+ GV + S       G    T  P      GL    
Sbjct: 2050 TTFHSSPRSPATTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS 2105

Query: 1076 VLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETA-APGVEDISGLPSGEVL 1134
                ++PG  D + LP+     T+ P  E  +   S    +TA +PG             
Sbjct: 2106 TTSHSSPGSTDTTLLPASTT--TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2163

Query: 1135 ETAAPGVEDISGLPSGEVLETAAPGVEDISGL---PSGEVLETAAPGVEDISGLPSGEVL 1191
              ++PG    +  P      T + G+ + S      +G    T +P      GL      
Sbjct: 2164 FHSSPGSTHTTLFPDS----TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 2219

Query: 1192 ETAAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLE 1249
                P     +  P      TA   VE+ +      G    T  P     SG      + 
Sbjct: 2220 FQTHPASTHTTPSPPS----TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 2275

Query: 1250 TAAPGVEDISGL-PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETT 1308
             ++P   D SG  PS     T+  G    S +  G    TT PG              TT
Sbjct: 2276 HSSP---DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG-------------STT 2319

Query: 1309 APGVDEISG-LPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLS-----------GL 1356
             PG+ E S    S     TT      ++ L  GE   TS S  G              GL
Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379

Query: 1357 PSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPS 1416
                  +  S  G  + +  P      TS  G E+ +   S      +    ED +    
Sbjct: 2380 SEESTTVYSSSPGSTETTVFP--RTPTTSVRG-EEPTTFHSRPASTHTTLFTEDSTTSGL 2436

Query: 1417 GEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLP 1476
             EE      S     +GLP+       + +++G + +  PS      +S S    LS   
Sbjct: 2437 TEESTAFPGSPASTQTGLPA-----TLTTADLGEESTTFPS------SSGSTGTTLSPAR 2485

Query: 1477 SGKEDLVG-SASGDLDLGKLPSGTL-GSGQAPETSGLPSGFSGEYSGVDLGSGPP----S 1530
            S    LVG S    L      + TL GS   P  S   + F       D    P     S
Sbjct: 2486 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 2545

Query: 1531 GLPDFSGL----PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSEL 1586
            G+ + S      P    T +  DST        T   L    T   S  G      ++ L
Sbjct: 2546 GVSEESSTSHSQPGSTHTTAFPDST--------TTPGLSRHSTTSHSSPGSTD---TTLL 2594

Query: 1587 DISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVS-GQPSG-FPDTSGETSGVTELSGL 1644
              S   SG    +  S  + GS D +        +S GQ S  F  + G T   T L   
Sbjct: 2595 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTH--TTLFPD 2652

Query: 1645 SSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSG 1704
            S+   GI   ++ V   T  P   T LS  +S  P L G+ +       +T   P   S 
Sbjct: 2653 STTSSGIVEASTRVHSSTGSPR--TTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710

Query: 1705 TTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQF 1764
             T+   ES               TT+    G          S  +  S KS +   S   
Sbjct: 2711 ATAPVEES---------------TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 2755

Query: 1765 SGTVDSSGFTSQTPEFSGLPSGIAEVSGE-----SSRAEIGSSLPSGAYYGSGTPSSFPT 1819
            SGT  SS  ++ +       S I+  S E      S    G S  S  +Y S  P S PT
Sbjct: 2756 SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS--PRS-PT 2812

Query: 1820 VSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLS-GLQSGLI 1878
             +L   ++        +     +  S    +S A +  P +S E +     S G     +
Sbjct: 2813 TTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV 2872

Query: 1879 EPS-------GEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEG- 1930
             P        GE P T + S   ++ T +  E S   G + E++  P     T   +   
Sbjct: 2873 FPRSTTTSVRGEEP-TTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPAT 2931

Query: 1931 VTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETS 1990
            +T   + +E    P  + +     S  + +T+G +  +TP         S +  SS+ET+
Sbjct: 2932 LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP---------SRLSPSSTETT 2982

Query: 1991 AYPEAGFGASAAPEASREDSGSPDLSETTSAFH------EANLE--RSSGLGVSGSTLTF 2042
              P +                +P LSE ++ F+      +A L    ++  GVS  + T 
Sbjct: 2983 TLPGS--------------PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 3028

Query: 2043 QEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTS 2102
                 S       +STTTS +  E    P+A+ ++ G         S   S LG   +T 
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQE----PTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084

Query: 2103 IPESEWTQQTQRPAETHLE--IESSSLLYSGE-ETHTVETATSPTDASIPAS----PEWK 2155
                  T+ T  P +T     +E+S+  +S     HT  T  S T A +         W 
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 3144

Query: 2156 RESESTAAAPARSCA 2170
              S++T + P  + A
Sbjct: 3145 SSSDTTPSPPGTTAA 3159



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 150/651 (23%), Positives = 230/651 (35%), Gaps = 62/651 (9%)

Query: 1537 GLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLP 1596
            G  +G+  +   +S +V V    T + ++  G +  +  G+         D  GRA G  
Sbjct: 79   GASAGWSVMFAGESVVVLVHLWMTGARVKNLGLVEFASPGD---------DGDGRAEGFS 129

Query: 1597 SGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGET------SGVTELSGLSSGQPG 1650
             G  LS QA  +     E           SGF   +G T         T  S  SS  P 
Sbjct: 130  LGLPLSEQARAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPF 189

Query: 1651 ISGEASGV----LYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706
             +    GV    + G++      D S  +    + +   SG PG +G T       +   
Sbjct: 190  TTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSG-PGATGTTLFPSHSATSVF 248

Query: 1707 SGSGESSGITF--VDTSLVEVAPTTFKEEEGLGSVELSG------LPSGEADLSGKSGMV 1758
             G  ++S IT   ++T+ +  + TT    E   +   S       L       SG S   
Sbjct: 249  VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKS 308

Query: 1759 DVSGQFSGTVDSSGFTSQT--PEFSGLPSGIAEVSGESSRA-EIGSSLPSGAYYGSGTPS 1815
              S    G   +  F   T  P  S   +    + G +      G++ PS     S T  
Sbjct: 309  TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFH 368

Query: 1816 SFP----TVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGA--HSGAPDMSGEHSGFL 1868
            S P    T  L D T    + +A T   +  G P   L  S +  H G P          
Sbjct: 369  SSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSK 428

Query: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL---PEVTLITS 1925
            D S   SG      +   T + S     TT+ S  SS  +G S E++ +   P  T  T 
Sbjct: 429  DTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA-SSTTLGHSEESTPVHSSPVATATTP 487

Query: 1926 EFVEGVTEPTISQELG-QRPP----VTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVS 1980
                  T   + +     R P      H P+   +SG    +    G+T     S     
Sbjct: 488  PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSS---TP 544

Query: 1981 SVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTL 2040
            S   + + TS +   G   S      R+ S     SE + A H +    ++ +  +GST 
Sbjct: 545  STTAALAHTSYHSSLG---STETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTP 601

Query: 2041 TFQEGEASAAPEVSGESTTTSDVG-TEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVI 2099
            +   G+++ +P  SG   TT+  G T  PGL   + T        S   S  T+ L   +
Sbjct: 602  SVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF------YSSPRSPDTTHLPASM 655

Query: 2100 STSIPESEWTQQTQRPAETHLEIESSSLLYSG--EETHTVETATSPTDASI 2148
            ++S    E T    RP  TH      S    G  +E+    ++  PTD ++
Sbjct: 656  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL 706



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 295/1322 (22%), Positives = 449/1322 (33%), Gaps = 215/1322 (16%)

Query: 648  PGVRTVYLYPNQTGLP----DPLSRH------HAFCFRGISAVPSPGEEEGGTPTSPSGV 697
            PG     ++P  T       +P + H      H   F   S      EE    P SP+  
Sbjct: 3948 PGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 4007

Query: 698  EEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPG- 756
            +    T +   +    + EE+T  PS   +   + +      +      TP   SP    
Sbjct: 4008 Q----TGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE 4063

Query: 757  --ILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPS 814
               LP  P T + +E+ST   ++   P A+  P+ +     SEE S S     S      
Sbjct: 4064 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH---- 4119

Query: 815  VELFPSEEPFP--SKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTG 872
               FP        S+EP+ S     S    T +   P  T   S G++S     S   T 
Sbjct: 4120 TTAFPDSTTTSGLSQEPTTSHSSQGS----TEATLSPGSTTASSLGQQSTTFHSSPGDTE 4175

Query: 873  SGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLT--STVGSGLPVES----GLPSGDEERI 926
            +  +      SG +     +   +G L ++ LT  S+  +GL  ES      PS  +   
Sbjct: 4176 TTLLPDDTITSGLVEASTPTHSSTGSLHTT-LTPASSTSTGLQEESTTFQSWPSSSDTT- 4233

Query: 927  EWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTA 986
              PS P+   +P     +E S +     S  P+     T  S      G         ++
Sbjct: 4234 --PSPPSTTAVP-----VEVSTTYHSRPSSTPT-----THFSASSTTLGRSEESTTVHSS 4281

Query: 987  PGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGV 1046
            PG        +G  L  T      + G P      TT+P       + SG    T  PG 
Sbjct: 4282 PGA-------TGTALFPTRSATSVLVGEP------TTSP-------ISSGSTETTALPGS 4321

Query: 1047 EDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVED---ISGLPSGEVLETAAPGV 1103
               +GL        ++P   D +  P+     TT+ GV +    S    G +  TA P  
Sbjct: 4322 TTTAGLSEKSTTFYSSPRSPDTTLSPA----STTSSGVSEESTTSHSRPGSMHTTAFPSS 4377

Query: 1104 EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDI 1163
              + G+        ++PG  D           T +PG    S L        ++PG  + 
Sbjct: 4378 TTMPGVSQESTASHSSPGSTD----------TTLSPGSTTASSLGPESTTFHSSPGSTET 4427

Query: 1164 SGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1223
            + LP      T A G           +LE + P V   +G P      T +P     S  
Sbjct: 4428 TLLPD----NTTASG-----------LLEASTP-VHSSTGSPH----TTLSPAG---STT 4464

Query: 1224 PSGEVLETAA-PGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS 1282
              GE     + P  +D +  P      T +  VE          L T + G    +    
Sbjct: 4465 RQGESTTFQSWPNSKDTTPAPP----TTTSAFVE----------LSTTSHGSPSSTPTTH 4510

Query: 1283 GEVLETTAPGVEEISGLPSGEVLETT--APGVDEISGLPSGEVLETTAPGVEEISGLPS- 1339
                 TT    EE + + S  V   T  +P     SGL        ++PG  +    P  
Sbjct: 4511 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPES 4570

Query: 1340 ------GEVLETS-TSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV 1392
                  GE   TS +S    +S  PS    L    +      G        T+ +   D 
Sbjct: 4571 NTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG-------STATTHFPD- 4622

Query: 1393 SELPSGEGLETSASGVEDLSRLPSGEEVLEISASG---FGDLSGLPSGGEGLETSASEVG 1449
            S   SG   E++AS     S+  +G  VL   ++     G+ +  P     +ET+A    
Sbjct: 4623 SSTTSGRSEESTAS---HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679

Query: 1450 TDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETS 1509
            T   GL        +S S         S         S  +    + + T  S     TS
Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739

Query: 1510 GLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTA--STASELEGR 1567
            GL    +  +S    GS      P+ S             S+    +++  ST S L   
Sbjct: 4740 GLVEESTAYHSSP--GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE 4797

Query: 1568 GTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSG--EIPGLFGVSGQP 1625
             T   S  G I+   ++    S   SG    +E S  +  SPD +G   +P  F  SG+ 
Sbjct: 4798 PTSYHSSPGSIA---TTHFPESSTTSG---RSEESTASHSSPDTNGITPLPAHFTTSGRI 4851

Query: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685
            +           +      ++  PG+S + S +LY +S+    T LS  +     +SG+P
Sbjct: 4852 AESTTFYISPGSMETTLASTATTPGLSAK-STILYSSSRSPDQT-LSPASMTSSSISGEP 4909

Query: 1686 SGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
            + L   + +T       S TTSG  + S              TTF  + G          
Sbjct: 4910 TSLYSQAESTHTTAFPASTTTSGLSQES--------------TTFHSKPG---------- 4945

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDS---SGFTSQTPEFSGLPSGIAEVS-------GESS 1795
            S E  LS  S       Q   T  S   S  ++ +P  + +P G++E S       G + 
Sbjct: 4946 STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVP-GLSEESTTFYSSPGSTE 5004

Query: 1796 RAEIGSSLPSGAYYGSGTPSSFP-----TVSLVDRTLVES-VTQAPTAQEAGEGPSGILE 1849
                  S     +    TP  FP     T +++  TL  + + Q  TA  +    +G   
Sbjct: 5005 TTAFSHSNTMSIHSQQSTP--FPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTP 5062

Query: 1850 LSGAHSGAPDMSGEHSGF-----------LDLSGLQSGLIEPSGEPPGTPYFSGDFASTT 1898
            L  A S A D+ GE + F              S   SGL E S     +P F+    ST 
Sbjct: 5063 LP-ARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTE 5121

Query: 1899 NV 1900
            ++
Sbjct: 5122 SL 5123



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 156/611 (25%), Positives = 225/611 (36%), Gaps = 101/611 (16%)

Query: 1635 TSGVTELSGLSSGQPG----ISGEASGVLYGTSQPF-------GITD--LSGETSGVPDL 1681
            +SGV+E S  S  +PG    I+   S  + G SQ         G TD  LS  T+    L
Sbjct: 301  SSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL 360

Query: 1682 SGQPSGL---PGFSGATSGVPDLVSGTTSGSGESSGITFVDTSL--VEVAPTTFKEEEGL 1736
              + +     PG++  T+ +PD  + TTSG  E+S      T      ++P++    EG 
Sbjct: 361  GPESTTFHSSPGYT-KTTRLPD--NTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGE 417

Query: 1737 GSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGL------------- 1783
             +      PS +      SG      + S T  SS  ++ T  FS               
Sbjct: 418  PTT-FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 476

Query: 1784 ---PSGIAEVSGESSRAEIGSSLPSGAYY---GSGTPSSFPTVSLVDRTLVESVT-QAPT 1836
               P   A     +  A  G    S AY+   GS     FP  S       ES T    T
Sbjct: 477  HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 536

Query: 1837 AQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFAS 1896
                   PS    L+     +   S E + F D S + SG  E S     +P    D  +
Sbjct: 537  THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI-SGRSEESKASHSSP----DAMA 591

Query: 1897 TTNVSGES--SVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELG------QRPPVTH 1948
            TT +   S  SV +G S   S +   ++ T+      T+P +S++        + P  TH
Sbjct: 592  TTVLPAGSTPSVLVGDS-TPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTH 650

Query: 1949 TPQLFESSGKVSTAGDISGATP------VLPGS----GVEVSSVPESSS----ETSAYPE 1994
             P    SSG VS     S + P        PGS    G+   S    SS    +T+  P 
Sbjct: 651  LPASMTSSG-VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPG 709

Query: 1995 AGFGASAAPE--------ASREDSGSPD------LSETTSAFHEANLERSSGLGVSGSTL 2040
            +   +S  PE         S E +  PD      L E +   H +     + L  +GST 
Sbjct: 710  STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTT 769

Query: 2041 ------TFQEGEASAAPEVSGESTTTSDV--GTEAPGLPSATPTAS-GDRTEISGDLSGH 2091
                  TF    +S     +  +TT++ V   T + G PS+ PT     R+  SG +   
Sbjct: 770  RQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEES 829

Query: 2092 TSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPAS 2151
            T+        S P S  T        T    E S+  +S   THT+ +A S T A +   
Sbjct: 830  TTY------HSSPGSTQTMHFPESDTTSGRGEESTTSHSST-THTISSAPSTTSALVEEP 882

Query: 2152 PEWKRESESTA 2162
              +     STA
Sbjct: 883  TSYHSSPGSTA 893



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 170/792 (21%), Positives = 243/792 (30%), Gaps = 83/792 (10%)

Query: 690  TPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAIL--EFTTEPENQTEWEPAYT 747
            T   PS      V+Q      + P   +TT  P   T + L  E TT   +    E    
Sbjct: 4371 TTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 4430

Query: 748  PVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFP 807
            P  T+   G+L    P       ST  P  T  P+ S         F S   S    P P
Sbjct: 4431 PDNTTA-SGLLEASTPV----HSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 4485

Query: 808  SVRPFPSVELFPSEEPFPSKEPSPSEEPSA-----SEEPYT--PSPPVPSWTELPSSGEE 860
                   VEL  +    PS  P+     S+     SEE  T   SP   + T  P+    
Sbjct: 4486 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4545

Query: 861  SGAPDVSGDFTGS--GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGL 918
            SG  + S  +  S     + H   S   SG       S     S  T T+ S     S L
Sbjct: 4546 SGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTS----HSSTTHTISSAPSTTSAL 4601

Query: 919  ---------PSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASG 969
                       G      +P + T       +     S    G +  LP+         G
Sbjct: 4602 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV-LPARSTTSV-LLG 4659

Query: 970  VGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVED 1029
                S + SG +  T  PG     GL        ++P     +   +     TT    E+
Sbjct: 4660 ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSAS---STTLGRSEE 4716

Query: 1030 ISGLPSGEVLETT--APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDI 1087
             + + S  V   T  +P     SGL        ++PG       P      +TA G  + 
Sbjct: 4717 STTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE----SSTASGRSEE 4772

Query: 1088 SGLPSGEVLETAAPGVEDISGL---------PSGEVLETAAPGVEDISGLPSGEVLETAA 1138
            S         T +      S L           G +  T  P     SG         ++
Sbjct: 4773 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 4832

Query: 1139 PGVEDISGLP-----SGEVLETA----APGVEDISGLPSGEVLETAAPGVEDISGLPS-G 1188
            P    I+ LP     SG + E+     +PG  + +   +      +A      S   S  
Sbjct: 4833 PDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 4892

Query: 1189 EVLETAAPGVEDISGLPSG------EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGL 1242
            + L  A+     ISG P+           TA P     SGL        + PG  + +  
Sbjct: 4893 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLS 4952

Query: 1243 PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSG 1302
            P      + A         P G  L T +P    + GL        ++PG  E +     
Sbjct: 4953 PGSITTSSFAQEFTTPHSQP-GSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHS 5011

Query: 1303 EVL------ETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLET----STSAVGD 1352
              +       T  P     +       L TT  G E  +   S +   T    + S   D
Sbjct: 5012 NTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASD 5071

Query: 1353 LSGLP-----SGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASG 1407
            L G P     S               SGL   E   T  +     S + S E LET A G
Sbjct: 5072 LVGEPTTFYISPSPTYTTLFPASSSTSGLT--EESTTFHTSPSFTSTIVSTESLETLAPG 5129

Query: 1408 VEDLSRLPSGEE 1419
            +    ++ +G++
Sbjct: 5130 LCQEGQIWNGKQ 5141


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score =  118 bits (295), Expect = 8e-26
 Identities = 325/1358 (23%), Positives = 452/1358 (33%), Gaps = 293/1358 (21%)

Query: 681  PSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEE-ETTAVPSGETTAILEFTTEPENQ 739
            P P  ++G       GV+        PG   +P +       P+G T    ++  + E  
Sbjct: 222  PGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQY--KGEKG 279

Query: 740  TEWEPAYTPVGTSPLPGI-----LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPF 794
            +E EP    +      GI     L  +P  G + E+ + G   +      + P     P 
Sbjct: 280  SEGEPGIRGISLKGEEGIMGFPGLRGYP--GLSGEKGSPGQKGSRGLDGYQGPDGPRGP- 336

Query: 795  PSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTEL 854
              E   P     P+  P PS+      +P     P    EP +  EP  P  P P    +
Sbjct: 337  KGEAGDPGPPGLPAYSPHPSLAKGARGDP---GFPGAQGEPGSQGEPGDPGLPGPPGLSI 393

Query: 855  PSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGD---------RASGLPSGDLDSSGLT 905
                +  G P   G     GD      + G    D            G P  D    GL 
Sbjct: 394  GDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLK 453

Query: 906  STVG-SGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEG-----SASGVGDLSGLPS 959
               G +G P   G P G      W           G E ++G        G   ++G P 
Sbjct: 454  GAKGRAGFPGLPGSP-GARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPG 512

Query: 960  -----GEVLETSASGVGDLSGLP-----------SGEVLETTAPGVEDISGLPS--GEVL 1001
                 G+  +    G   L G+P            G+    T  G     G+P   G   
Sbjct: 513  RKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKG 572

Query: 1002 ETTAPGVEDISGLP----------SGEVLETTAPGVEDISGLPSGEV--LETTAPGVEDI 1049
            +  +PG + + G P           G   +   PG+    G P GE+       PG++  
Sbjct: 573  DDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTP-GEMGPPGLGLPGLKGQ 631

Query: 1050 SGLPSGEVLETTAPGV----------------EDISGLPSGEVLETTAPGV----EDISG 1089
             G P G+      PG                  D+     G+  E   PG     + + G
Sbjct: 632  RGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPG 690

Query: 1090 LPSGEVLETAAPGVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVLETAA 1138
            LP G    T A G+  I G              G+      PG     G P G       
Sbjct: 691  LP-GPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIG-PRGSKGAVGL 748

Query: 1139 PGVEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET 1193
            PG +   G      P G   E   PG  ++ G   G   +   PG   + GLP     + 
Sbjct: 749  PGPDGSPGPIGLPGPDGPPGERGLPG--EVLGAQPGPRGDAGVPGQPGLKGLPG----DR 802

Query: 1194 AAPGVEDISGLPSGEVLETAAPGVEDISGL--PSGEVLETAAPGVEDISGLPSGEVLETA 1251
              PG     G+P         PG++   GL  PSG+      PG+    G P G+     
Sbjct: 803  GPPGFRGSQGMP-------GMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAP-GQEGPLG 854

Query: 1252 APGVEDISGLPS--GEVLETAAPGVEDISGLP--------SGEVLETTAPGVEEISGLPS 1301
             PG+    GLP   G+  +T APG   + GL         +GE     +PG + I G+P 
Sbjct: 855  LPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPG 914

Query: 1302 GEVL--ETTAPGVDEISGLP-----------SGEVLETTAPGVEEISGLPSGEVLETSTS 1348
               L  +  +PG+D   G+P            GE      PG++ ++G P  +       
Sbjct: 915  TPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFK------G 968

Query: 1349 AVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGV 1408
            + GD  G P    V+   + G++DI G              E   E P G      A G+
Sbjct: 969  SRGD-PGPPGPPPVI---LPGMKDIKG--------------EKGDEGPMGLKGYLGAKGI 1010

Query: 1409 EDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASG 1468
            + +  +P          SG   L G P   +G++      G  + GLP G  G+    +G
Sbjct: 1011 QGMPGIP--------GLSGIPGLPGRPGHIKGVKGDIGVPG--IPGLP-GFPGV----AG 1055

Query: 1469 AEDLSGLPS-----------GKEDLVG--SASGDL-DLG---KLPSGTLGSGQAPETSGL 1511
               ++G P            G+  L G   A+GD  D+G    LP G  G      T+G+
Sbjct: 1056 PPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLP-GRPGLKGERGTTGI 1114

Query: 1512 P--SGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT 1569
            P   GF GE      G+    G P  +G+        L   T    +T    S+ E  G 
Sbjct: 1115 PGLKGFFGE-----KGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGE-LGR 1168

Query: 1570 IGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFP 1629
            IG+ G     G P         A GLP          G P + G I GL G+ G   GFP
Sbjct: 1169 IGLPGGKGDDGWPG--------APGLP----------GFPGLRG-IRGLHGLPG-TKGFP 1208

Query: 1630 DTSGETSGVTELSGLSSGQPGISGEAS--GVLYGTSQPFGITDLSGETSGVPDLSGQPS- 1686
             + G     +++ G   G PG  GE    G       P G+    G+  G P   G P  
Sbjct: 1209 GSPG-----SDIHG-DPGFPGPPGERGDPGEANTLPGPVGVPGQKGD-QGAPGERGPPGS 1261

Query: 1687 -GLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLP 1745
             GL GF G T   P  +SG     G               AP  F    GL        P
Sbjct: 1262 PGLQGFPGITP--PSNISGAPGDKG---------------APGIF----GLKGYRGPPGP 1300

Query: 1746 SGEADLSGKSGMVDVSGQFSGTVDSSGFTSQT-----PEFSGLPSGIAEVSGESSRAEIG 1800
             G A L G  G     G   GT  + G+   +     P   GLP    E      +  +G
Sbjct: 1301 PGSAALPGSKGDTGNPGA-PGTPGTKGWAGDSGPQGRPGVFGLP---GEKGPRGEQGFMG 1356

Query: 1801 SSLPSGAYYGSGTPS-----SFP-TVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAH 1854
            ++ P+GA    G         FP     V    +  + Q    Q    GP G        
Sbjct: 1357 NTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQG-------R 1409

Query: 1855 SGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSG 1892
             G P   GE              + P G PPG P F G
Sbjct: 1410 RGPPGAPGE--------------MGPQG-PPGEPGFRG 1432



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 238/1002 (23%), Positives = 336/1002 (33%), Gaps = 176/1002 (17%)

Query: 750  GTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSV 809
            G    PG+       GA   +  +G S T + +  E   P     P  +          +
Sbjct: 524  GLPGFPGLKGVPGNIGAPGPKGAKGDSRT-ITTKGERGQPGVPGVPGMKGDDGSPGRDGL 582

Query: 810  RPFPSVELFPSEE-PFPSKEPSPSEEPSASEEPYTPSPP------------VPSWTELPS 856
              FP +   P +    P  +P     P     P    PP             P    LP 
Sbjct: 583  DGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPG 642

Query: 857  SGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGL----------------PSGDLD 900
                 G P  +G     G +    D    + GDR   +                P G   
Sbjct: 643  PPGFLGPPGPAGT---PGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTG 699

Query: 901  SSGLTSTVG----SGLPVESGLPSGDEERIEWPSTPT-VGELPS-GAEILEGSASGVGDL 954
            + GL    G     G P   GLP GD  R  +P  P  +G   S GA  L G     G +
Sbjct: 700  AKGLRGIPGFAGADGGPGPRGLP-GDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPI 758

Query: 955  SGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL 1014
             GLP  +         G++ G   G   +   PG   + GLP     +   PG     G+
Sbjct: 759  -GLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPG----DRGPPGFRGSQGM 813

Query: 1015 PSGEVLETTAPGVEDISGLP--SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1072
            P         PG++   GLP  SG+      PG+    G P G+      PG+    GLP
Sbjct: 814  PG-------MPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAP-GQEGPLGLPGIPGREGLP 865

Query: 1073 S--GEVLETTAPGVEDISGLP--------SGEVLETAAPGVEDISGLPSGEVL--ETAAP 1120
               G+  +T APG   + GL         +GE     +PG + I G+P    L  +  +P
Sbjct: 866  GDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSP 925

Query: 1121 GVEDISGLPS-----------GEVLETAAPGVEDISGLPSGEVLE----------TAAPG 1159
            G++   G+P            GE      PG++ ++G P  +                PG
Sbjct: 926  GMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG 985

Query: 1160 VEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAA 1214
            ++DI G      P G      A G++ + G+P      +  PG+    G   G   +   
Sbjct: 986  MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPG----LSGIPGLPGRPGHIKGVKGDIGV 1041

Query: 1215 PGVEDISGLP--SGEVLETAAPGV---EDISGLPS-----GEVLETAAPG-VEDISGLPS 1263
            PG+  + G P  +G    T  PG        G P      GE+  T   G + D   LP 
Sbjct: 1042 PGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPG 1101

Query: 1264 -----GEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGL--PSGEVLETTAPGVDEIS 1316
                 GE   T  PG++   G   G   +   PG+  ++G+  P G   +T  PG+    
Sbjct: 1102 RPGLKGERGTTGIPGLKGFFG-EKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPP 1160

Query: 1317 GLPSGEVLETTAPGVEEISGLPSGEVLE--TSTSAVGDLSGLPSGGEVLEISVSGVEDIS 1374
            G   GE+     PG +   G P    L        +  L GLP          S +    
Sbjct: 1161 G-SQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDP 1219

Query: 1375 GLPSGEVVETSASGIEDVSELPSGEGL-----------ETSASGVEDLSRLPSGEEVLEI 1423
            G P G   E    G  + + LP   G+           E    G   L   P       I
Sbjct: 1220 GFP-GPPGERGDPG--EANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNI 1276

Query: 1424 S-------ASGFGDLSGL-----PSGGEGLETSASEVGTDLSGLPSGREGL--ETSASGA 1469
            S       A G   L G      P G   L  S  + G   +    G +G   ++   G 
Sbjct: 1277 SGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGR 1336

Query: 1470 EDLSGLPS-----GKEDLVGSASGDLDLG----KLPSGTLGSGQAPETSGLPSGFSG--E 1518
              + GLP      G++  +G+      +G    K P G  G   AP T G P G +G  +
Sbjct: 1337 PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAP-GIAGIPQ 1395

Query: 1519 YSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGT---IGISGA 1575
               V  G+  P G     G P              E+       E   RG     G  G 
Sbjct: 1396 KIAVQPGTVGPQGRRGPPGAPG-------------EMGPQGPPGEPGFRGAPGKAGPQGR 1442

Query: 1576 GEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPG 1617
            G +S +P    D        P G E +    GSP + G +PG
Sbjct: 1443 GGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPG-MPG 1483



 Score = 37.0 bits (84), Expect = 0.24
 Identities = 93/353 (26%), Positives = 117/353 (33%), Gaps = 52/353 (14%)

Query: 1498 GTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPS--------GFPTVSLVD 1549
            G  G   AP  +G P G        D+G+   SG P   G+P         G P     +
Sbjct: 88   GDKGERGAPGVTG-PKG--------DVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCN 138

Query: 1550 STLVEVVTASTASELEGRGTIGISGA----GEISGLPSSELDISGRASGLPSGTELSGQA 1605
             T  +             G  G  G     GE   LP  E D      G P      G  
Sbjct: 139  GTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPP 198

Query: 1606 SGSPDVSGEIPGLFGVSGQPS--GFPDTSGETS-------GVTELSGLSSGQPGISGEAS 1656
             G P   G++ G  G  G+P   G P   G+         GV    G   GQPG +G  S
Sbjct: 199  -GRPGHVGQM-GPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKG-DVGQPGPNGIPS 255

Query: 1657 GVLYGTSQPFGITDLSGETSGVPDLSGQP----------SGLPGFSGATSGVPDLVSGTT 1706
              L+    P G+T    +  G     G+P           G+ GF G   G P L SG  
Sbjct: 256  DTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPG-LRGYPGL-SG-E 312

Query: 1707 SGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSG 1766
             GS    G   +D       P   K E   G     GLP+     S   G     G F G
Sbjct: 313  KGSPGQKGSRGLDGYQGPDGPRGPKGE--AGDPGPPGLPAYSPHPSLAKGARGDPG-FPG 369

Query: 1767 TVDSSGFTSQTPEFSGLPS--GIAEVSGESSRAEIGSSLPSGAYYGSGTPSSF 1817
                 G   + P   GLP   G++   G+  R   G   P G     G P+ +
Sbjct: 370  AQGEPGSQGE-PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALY 421


>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
          Length = 1479

 Score =  117 bits (292), Expect = 2e-25
 Identities = 83/266 (31%), Positives = 121/266 (45%), Gaps = 29/266 (10%)

Query: 2066 EAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESS 2125
            E  G    + T   ++T I+G L+G++S L + ++       W      P + +L  ES 
Sbjct: 267  EQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLK-YLNWESD 325

Query: 2126 SLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGH 2185
                  EE   V    S        S  W+    S A      C ++P    T + T   
Sbjct: 326  QPDNPSEENCGVIRTES--------SGGWQNRDCSIALPYV--CKKKP--NATAEPT--- 370

Query: 2186 VICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIV 2245
                 PP       N+  E CE  W  +QGHCYR   ++ +W ++++ C      L SI 
Sbjct: 371  -----PPD---RWANVKVE-CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIH 421

Query: 2246 TPEEQEFVNNNAQ---DYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDC 2302
            +  E EF+    +   +  WIGLND  ++ +F WSDG  + F +W P +P+NF  + EDC
Sbjct: 422  SMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDC 481

Query: 2303 VVMIWHEKGEWNDVPCNYHLPFTCKK 2328
            V  IW  +G WND PCN  LP  CKK
Sbjct: 482  VT-IWGPEGRWNDSPCNQSLPSICKK 506



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 12/172 (6%)

Query: 2175 GAGTCKETEGHVICLCPPGYTGEH----CNIDQEVCEEGWNKYQ--GHCYR-HFPDRETW 2227
            G  +    +GH+ C     Y  +     C I    CE  W+K Q    CY+ +F    +W
Sbjct: 200  GCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSW 259

Query: 2228 VDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQF 2284
             +A   C +Q + L SI    EQ ++N     Y    WIGLND    G ++WSD  P+++
Sbjct: 260  REAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKY 319

Query: 2285 ENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEP 2336
             NW  +QPDN   + E+C V+     G W +  C+  LP+ CKK   A  EP
Sbjct: 320  LNWESDQPDN--PSEENCGVIRTESSGGWQNRDCSIALPYVCKKKPNATAEP 369



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 63/219 (28%), Positives = 97/219 (44%), Gaps = 25/219 (11%)

Query: 2181 ETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSH 2240
            +T+   IC  P G T      D       W ++Q   Y+ F    TW  A+R C   Q+ 
Sbjct: 801  DTQLDWICKIPRG-TDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRICTWFQAE 859

Query: 2241 LSSIVTPEEQEFVNNNAQDYQ-------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPD 2293
            L+S+ +  E +F+++N Q +        WIGL+    +G FRW+DG  + F +W P +P 
Sbjct: 860  LTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPR 919

Query: 2294 NFFAAGED--CVVMIWHEKGEWNDVPCNYHLPFTCKKGTVAC-GEPPVVEHARTFGQKKD 2350
                 G+D  CV M    + +W D  C   LP+ CK+  V    +PP +      G   D
Sbjct: 920  ---PVGKDKKCVYMT-ASREDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSD 975

Query: 2351 RYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITC 2389
              +  +    +C +  VQ   P  R +    W E Q +C
Sbjct: 976  WIQFLN----KCFQ--VQGQEPQSRVK----WSEAQFSC 1004



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 31/180 (17%)

Query: 2180 KETEGHVICLCPPGYTGEHCNIDQEV------------CEEGWNKYQGHCYR----HFPD 2223
            +E  G   CL    Y  +  N+ +E             C   W ++   C++        
Sbjct: 934  REDWGDQRCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQS 993

Query: 2224 RETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGH 2280
            R  W +A+  C +Q++ L +I  P EQ F+  +  +     WIGL+    + DF+W +  
Sbjct: 994  RVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQE 1051

Query: 2281 PMQFENWRPNQPDNFFAAGE-----DCVVMIW----HEKGEWNDVPCNYHL-PFTCKKGT 2330
            P+ + NW P +P     A        C V++     H  G W+D  C      F C+KGT
Sbjct: 1052 PLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGT 1111



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 25/144 (17%)

Query: 2206 CEEGW--NKYQGHCYRHFP-----DRETWVDAERRCREQQSHLSSIVTPEEQEFVNN--- 2255
            C +GW  +    +CY+ F      D+++WV A+  C+E  + L S+ + EE+ FV N   
Sbjct: 669  CPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLN 728

Query: 2256 ----------NAQDYQWIGLNDRTIEG--DFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2303
                      + Q + WIGLN R   G   +RWSDG    + N+  ++ D+    G  C 
Sbjct: 729  KIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG--CA 786

Query: 2304 VMIWHEKGEWNDVPCNYHLPFTCK 2327
            V+      +W  + C+  L + CK
Sbjct: 787  VLDLASL-QWVAMQCDTQLDWICK 809



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 48/194 (24%), Positives = 78/194 (40%), Gaps = 16/194 (8%)

Query: 2206 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVN----NNAQDYQ 2261
            C +GW  +   CY    D+ T+ +A R C +  S L +I    EQ FV+    N   +Y 
Sbjct: 521  CRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYF 580

Query: 2262 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPC-NY 2320
            W  L D    G F W  G  + + +W  +QP   ++ G    +      G W    C ++
Sbjct: 581  WTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVKNCTSF 638

Query: 2321 HLPFTCKK--GTVACGEPPVVEHARTF-GQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQ 2377
               + C++  GT    E P  +   +  G     +  ++ +RY C + F        R Q
Sbjct: 639  RARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRY-CYKVFSSE-----RLQ 692

Query: 2378 PSGHWEEPQITCTD 2391
                W + Q  C +
Sbjct: 693  DKKSWVQAQGACQE 706



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 9/145 (6%)

Query: 2191 PPGYTGEHCNIDQEVCEEGWNKYQGHCYR-HFPDRETWVDAERRCREQQSHLSSIVTPEE 2249
            PP     H +  Q + +  W  ++ HCY  H        +A +RC+     + SI+   E
Sbjct: 1251 PPRRISYHGSCPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEME 1310

Query: 2250 QEFVNNNAQDYQ------WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCV 2303
              FV  + Q Y+      W+G+N     G   W D   + + NW P        +   C 
Sbjct: 1311 NVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSC- 1369

Query: 2304 VMIWHEKGEWNDVPC-NYHLPFTCK 2327
              I    G W    C N  +   CK
Sbjct: 1370 YWIQSNSGLWRPGACTNITMGVVCK 1394



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 2227 WVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEGDFRWSDGHPMQ 2283
            W DA   C  + + L+ +  P  Q F+   A+  +   WIGL        + W    P+ 
Sbjct: 1146 WHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVSEEPLN 1205

Query: 2284 FENWRPNQP 2292
            +  W+  +P
Sbjct: 1206 YVGWQDGEP 1214


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  116 bits (291), Expect = 2e-25
 Identities = 294/1158 (25%), Positives = 393/1158 (33%), Gaps = 249/1158 (21%)

Query: 795  PSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPS----PSEEPSASEEPYTPSPPVPS 850
            P  +  P   P P+  P PS +  P   P P   P     P  +    +  ++P  PVP 
Sbjct: 490  PKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPG 549

Query: 851  WTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP--SGDLDSSGLTSTV 908
                       G P + GD      + GH    G L G++  G+P  +G++ S G     
Sbjct: 550  EKGDQGLSGLMGPPGMQGD----KGLKGHPGLPG-LPGEQ--GIPGFAGNIGSPGYPGRQ 602

Query: 909  GSGLPVESGLPSGDEERIEWPSTPTVGEL-PSGAEILEG--SASGVGDLSGLPSGEVLET 965
            G   P  +  P G +  I  P     G+L P G   + G     G     G P G+  + 
Sbjct: 603  GLAGPEGNPGPKGAQGFIGSPGE--AGQLGPEGERGIPGIRGKKGFKGRQGFP-GDFGDR 659

Query: 966  SASGVGDLSGLPSGEVLETTAPGVEDISGL--PSGEVLETTAPGVEDISGLPSGEVLETT 1023
              +G+    GL  G    T  PG   + G   P G +     PG   +SG          
Sbjct: 660  GPAGLDGSPGLVGG----TGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSG-------NKG 708

Query: 1024 APGVEDISGLP--SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTA 1081
             PG++   G    +GE+ E   PG +   GLP         PG+   SG PSG+   T  
Sbjct: 709  LPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPG-------PPGMRGKSG-PSGQ---TGD 757

Query: 1082 PGVEDISGLPSGEVL--ETAAPGVEDISGLPSGEVLETAAPGVEDISGLPS--------G 1131
            PG++  SG P  E    +   PG     G P G +     PG   + G           G
Sbjct: 758  PGLQGPSGPPGPEGFPGDIGIPGQNGPEG-PKGLLGNRGPPGPPGLKGTQGEEGPIGAFG 816

Query: 1132 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1191
            E+     PG +  +G P  E L+       +I  +  GE      PG   ++G   GE  
Sbjct: 817  ELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKI--GETGPVGLPGEVGMTG-SIGEKG 873

Query: 1192 ETAAPGVEDISGLPSGEVLETAAPGVEDISG------LPSGEVLETAAPGVEDISGL--- 1242
            E  +PG       P GE      PG   + G      LP G V     PG +   G    
Sbjct: 874  ERGSPGPLG----PQGEKGVMGYPGPPGVPGPIGPLGLP-GHVGARGPPGSQGPKGQRGS 928

Query: 1243 --PSGEVLETAAPGVEDISGL-----PSGEVLETAAPGVEDISGLPSGEVLETTAPGVEE 1295
              P G + E    G +   G      P G + +T  PG     G P  + L    PG   
Sbjct: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL----PGSTG 984

Query: 1296 ISGLPSGEVLETTAPGVDEISGL--PSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDL 1353
              GLP GE      PG+  + G   P GE+     PG E  SG      L+    A GD+
Sbjct: 985  DRGLP-GE------PGLRGLQGDVGPPGEMGMEGPPGTEGESG------LQGEPGAKGDV 1031

Query: 1354 SGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSR 1413
                                    +G V  T   G+      P  EGL+           
Sbjct: 1032 G----------------------TAGSVGGTGEPGLRGEPGAPGEEGLQ----------- 1058

Query: 1414 LPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG-TDLSGL--PSGREGLETSASGAE 1470
                         G   L G+P GG GL     E G   L G+  P GR G +T   G E
Sbjct: 1059 -------------GKDGLKGVP-GGRGLPGEDGEKGEMGLPGIIGPLGRSG-QTGLPGPE 1103

Query: 1471 DLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGL--PSGFSGEYSGV-DLGSG 1527
             + G+P G+    G       +G  P+G +GS   P   G   P G  G    V  LG  
Sbjct: 1104 GIVGIP-GQRGRPGKKGDKGQIG--PTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160

Query: 1528 PPSGLPDFSGL--PSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSE 1585
             P G P   G     G P                        G  G+ G     G P  +
Sbjct: 1161 GPDGEPGIPGYRGHQGQP------------------------GPSGLPGPKGEKGYPGED 1196

Query: 1586 LDISG----RASGLPSGTELSGQASGSPDVSGE--IPGLFGVSGQPSGFPDTSGETSGVT 1639
              + G    R    P G +      G+    G   +PGL G +GQ  G P   G+     
Sbjct: 1197 STVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQ-QGPPGEPGD----- 1250

Query: 1640 ELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSG--QPSGLPGFSGATSG 1697
                   G+ G+ GE      G     G    SG+  G+P L G   P G+ G+ GA   
Sbjct: 1251 ------QGEQGLKGERGS--EGNKGKKGAPGPSGK-PGIPGLQGLLGPKGIQGYHGA--- 1298

Query: 1698 VPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGM 1757
              D +SG     G                      ++GL  +   G P G   L+G  G 
Sbjct: 1299 --DGISGNPGKIGPPG-------------------KQGLPGIR--GGP-GRTGLAGAPGP 1334

Query: 1758 VDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSF 1817
              V G  SG   S G      E  GLP           R   G   P G     G P  +
Sbjct: 1335 PGVKGS-SGLPGSPGIQGPKGE-QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEY 1392

Query: 1818 PTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGL 1877
                L          Q     +  EG +GI+ +SG     P     H G     G + G+
Sbjct: 1393 GVQGLTG-------FQGFPGPKGPEGDAGIVGISG-----PKGPIGHRGNTGPLG-REGI 1439

Query: 1878 IEPSGE--PPGTPYFSGD 1893
            I P+G   P G   F G+
Sbjct: 1440 IGPTGRTGPRGEKGFRGE 1457



 Score =  114 bits (285), Expect = 1e-24
 Identities = 277/1053 (26%), Positives = 372/1053 (35%), Gaps = 190/1053 (18%)

Query: 770  ESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRP-FPSVELFPSEEPFPSKE 828
            E   GP     P     P P+ +P PS +  P   P P   P  P +       P P   
Sbjct: 485  EYLRGPKGDTGPPGP--PGPAGIPGPSGKRGPRGIPGPHGNPGLPGL-------PGPK-- 533

Query: 829  PSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSG 888
              P  +P      ++P  PVP            G P + GD      + GH    G L G
Sbjct: 534  -GPKGDPG-----FSPGQPVPGEKGDQGLSGLMGPPGMQGD----KGLKGHPGLPG-LPG 582

Query: 889  DRASGLP--SGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGEL-PSGAEILE 945
            ++  G+P  +G++ S G     G   P  +  P G +  I  P     G+L P G   + 
Sbjct: 583  EQ--GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPG--EAGQLGPEGERGIP 638

Query: 946  G--SASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGL--PSGEVL 1001
            G     G     G P G+  +   +G+    GL  G    T  PG   + G   P G + 
Sbjct: 639  GIRGKKGFKGRQGFP-GDFGDRGPAGLDGSPGLVGG----TGPPGFPGLRGSVGPVGPIG 693

Query: 1002 ETTAPGVEDIS---GLP-----------SGEVLETTAPGVEDISGLP--------SGEVL 1039
                PG   +S   GLP           +GE+ E   PG +   GLP        SG   
Sbjct: 694  PAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSG 753

Query: 1040 ETTAPGVEDISGLPSGEVL--ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPS----- 1092
            +T  PG++  SG P  E    +   PG     G P G +     PG   + G        
Sbjct: 754  QTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEG-PKGLLGNRGPPGPPGLKGTQGEEGPI 812

Query: 1093 ---GEVLETAAPGVEDISGLPSGEVLETAAPGVEDIS--------GLPSGEVLETAAPGV 1141
               GE+     PG +  +G P  E L+       +I         GLP GEV  T + G 
Sbjct: 813  GAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLP-GEVGMTGSIGE 871

Query: 1142 EDISGL-----PSGEVLETAAPGVEDIS------GLPSGEVLETAAPGVEDISGL----- 1185
            +   G      P GE      PG   +       GLP G V     PG +   G      
Sbjct: 872  KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLP-GHVGARGPPGSQGPKGQRGSRG 930

Query: 1186 PSGEVLETAAPGVEDISG-----LPSGEVLETAAPGVEDISGLPS-----GEVLETAAPG 1235
            P G + E    G +   G      P G + +T  PG     G P      G   +   PG
Sbjct: 931  PDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPG 990

Query: 1236 VEDISGL-----PSGEVLETAAPGVEDISGL-----------PSGEVLETAAPGVEDISG 1279
               + GL     P GE+     PG E  SGL            +G V  T  PG+    G
Sbjct: 991  EPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPG 1050

Query: 1280 LPSGEVLETTAPGVEEISGLPSGEVL-----ETTAPGVDEISGLPSGEVLETTAPGVEEI 1334
             P  E L+    G + + G+P G  L     E    G+  I G P G   +T  PG E I
Sbjct: 1051 APGEEGLQ----GKDGLKGVPGGRGLPGEDGEKGEMGLPGIIG-PLGRSGQTGLPGPEGI 1105

Query: 1335 SGLPSGE---VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIED 1391
             G+P        +     +G    + S G   +I  SG +   G   G V      G + 
Sbjct: 1106 VGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARG-TRGAVGHLGLMGPDG 1164

Query: 1392 VSELPS--GEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG 1449
               +P   G   +   SG+      P GE+       G+        G  G       VG
Sbjct: 1165 EPGIPGYRGHQGQPGPSGLPG----PKGEK-------GYPGEDSTVLGPPGPRGEPGPVG 1213

Query: 1450 TDLSGLPSGREGLE--------TSASGAEDLSGLP--SGKEDLVGSASGDLDLGKLPS-G 1498
                    G EG +          A+G +   G P   G++ L G    + + GK  + G
Sbjct: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPG 1273

Query: 1499 TLGSGQAPETSGL--PSGFSGEYSGVDLGSGPPS--GLPDFSGLP---SGFPTVSLVDST 1551
              G    P   GL  P G  G Y G D  SG P   G P   GLP    G     L  + 
Sbjct: 1274 PSGKPGIPGLQGLLGPKGIQG-YHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAP 1332

Query: 1552 LVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDV 1611
                V  S+       G+ GI G     GLP  +  I G+      G +      G P +
Sbjct: 1333 GPPGVKGSSGLP----GSPGIQGPKGEQGLP-GQPGIQGKRG--HRGAQGDQGPCGDPGL 1385

Query: 1612 SGEIPGLFGVSGQP--SGFPDTSGE--TSGVTELSGLSS--GQPGISGE--ASGVL--YG 1661
             G+ PG +GV G     GFP   G    +G+  +SG     G  G +G     G++   G
Sbjct: 1386 KGQ-PGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTG 1444

Query: 1662 TSQPFGITDLSGETSGVPDLSGQPSGLPGFSGA 1694
             + P G     GET G     GQP G PG  GA
Sbjct: 1445 RTGPRGEKGFRGET-GPQGPRGQP-GPPGPPGA 1475



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 151/567 (26%), Positives = 197/567 (34%), Gaps = 141/567 (24%)

Query: 1427 GFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSA 1486
            G   L GLP G +G+   A  +G+   G P GR+GL    +G E   G P G +  +GS 
Sbjct: 573  GHPGLPGLP-GEQGIPGFAGNIGSP--GYP-GRQGL----AGPEGNPG-PKGAQGFIGSP 623

Query: 1487 SGDLDLGKLPSGTLGSGQAPETSGLPSGFSGE--YSGVDLGSGPPSGLPDFSGL-----P 1539
                 LG  P G  G    P   G   GF G   + G D G   P+GL    GL     P
Sbjct: 624  GEAGQLG--PEGERG---IPGIRG-KKGFKGRQGFPG-DFGDRGPAGLDGSPGLVGGTGP 676

Query: 1540 SGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGT 1599
             GFP +                     RG++G  G    +G+P   + +SG   GLP   
Sbjct: 677  PGFPGL---------------------RGSVGPVGPIGPAGIPGP-MGLSGN-KGLPG-- 711

Query: 1600 ELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETS--GVTELSGLS--SGQPGISGEA 1655
             + G   G    +GE+       G+P G+P   G     G   + G S  SGQ G  G  
Sbjct: 712  -IKGD-KGEQGTAGEL-------GEP-GYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG-- 759

Query: 1656 SGVLYGTSQPFGITDLSGETSGVPDLSGQ--PSGLPGFSGATSGVPDLVSGTTSGSGESS 1713
               L G S P G     G+  G+P  +G   P GL G  G     P  + GT    G   
Sbjct: 760  ---LQGPSGPPGPEGFPGDI-GIPGQNGPEGPKGLLGNRGPPG--PPGLKGTQGEEGPIG 813

Query: 1714 GITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFS--GTVDSS 1771
                                   G +   G P G+   +G+ G   + G+    G +   
Sbjct: 814  AF---------------------GELGPRGKP-GQKGYAGEPGPEGLKGEVGDQGNIGKI 851

Query: 1772 GFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSG--------AYYGS-GTPSSFPTVSL 1822
            G T       GLP  +        + E GS  P G         Y G  G P     + L
Sbjct: 852  GETGPV----GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGL 907

Query: 1823 VDRTLVESV--TQAPTAQEAGEGPSGILELSG-----AHSGAPDMSGEHS---------- 1865
                       +Q P  Q    GP G+L   G        G     G H           
Sbjct: 908  PGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGE 967

Query: 1866 -GFLDLSGLQSGLIEPSGE-----PPGTPYFSGDFASTTNVSGESSVAMGTSGEASGL-- 1917
             GF    GLQ GL   +G+      PG     GD      +  E     GT GE SGL  
Sbjct: 968  RGFQGKPGLQ-GLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEG--PPGTEGE-SGLQG 1023

Query: 1918 ---PEVTLITSEFVEGVTEPTISQELG 1941
                +  + T+  V G  EP +  E G
Sbjct: 1024 EPGAKGDVGTAGSVGGTGEPGLRGEPG 1050


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,962,316
Number of Sequences: 37866
Number of extensions: 7109209
Number of successful extensions: 40897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 398
Number of HSP's successfully gapped in prelim test: 1306
Number of HSP's that attempted gapping in prelim test: 22096
Number of HSP's gapped (non-prelim): 10963
length of query: 2416
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2297
effective length of database: 13,741,464
effective search space: 31564142808
effective search space used: 31564142808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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