Guide to the Human Genome
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Name: ACAN Sequence: fasta or formatted (2317aa) NCBI GI: 126090883
Description:

aggrecan isoform 1 precursor

Referenced in:

Bone and Related Tissues
Protein Glycosylation
Extracellular Matrix

Other entries for this name:
alt prot [2416aa] aggrecan isoform 2 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        161           2
 C cysteine            1.0         24           1
 D aspartate           4.6        106           1
 E glutamate          11.0        255           3
 F phenylalanine       2.8         66           2
 G glycine            12.2        282           2
 H histidine           1.2         28           2
 I isoleucine          3.3         77           2
 K lysine              1.1         25           2
 L leucine             7.8        181           2
 M methionine          0.5         12           1
 N asparagine          1.2         28           3
 P proline             9.0        209           2
 Q glutamine           2.5         58           2
 R arginine            3.2         73           2
 S serine             12.7        294           3
 T threonine           8.2        190           3
 V valine              7.7        178           3
 W tryptophan          1.0         24           1
 Y tyrosine            2.0         46           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   aggrecan isoform 1 precursor 
ACAN                  0.985   aggrecan isoform 2 precursor 
BCAN                  0.075   brevican isoform 2 
BCAN                  0.075   brevican isoform 1 
VCAN                  0.073   versican isoform 1 
VCAN                  0.073   versican isoform 2 
NCAN                  0.066   chondroitin sulfate proteoglycan 3 
HAPLN3                0.043   hyaluronan and proteoglycan link protein 3 
HAPLN1                0.041   hyaluronan and proteoglycan link protein 1 
HAPLN2                0.036   brain link protein-1 
HAPLN4                0.036   hyaluronan and proteoglycan link protein 4 
COL3A1                0.027   collagen type III alpha 1 preproprotein 
COL4A1                0.025   alpha 1 type IV collagen preproprotein 
COL4A6                0.025   type IV alpha 6 collagen isoform A precursor 
COL4A6                0.025   type IV alpha 6 collagen isoform B precursor 
COL5A2                0.023   alpha 2 type V collagen preproprotein 
MUC4                  0.022   mucin 4 isoform a 
COL4A5                0.022   type IV collagen alpha 5 isoform 1 precursor 
COL4A5                0.022   type IV collagen alpha 5 isoform 2 precursor 
COL4A5                0.022   type IV collagen alpha 5 isoform 3 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 5 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 4 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 2 precursor 
COL4A3                0.021   alpha 3 type IV collagen isoform 1 precursor 
MRC2                  0.021   mannose receptor, C type 2 
COL5A3                0.021   collagen, type V, alpha 3 preproprotein 
MUC12                 0.020   PREDICTED: mucin 12 
COL4A2                0.020   alpha 2 type IV collagen preproprotein 
COL24A1               0.020   collagen, type XXIV, alpha 1 
COL7A1                0.020   alpha 1 type VII collagen precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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