Guide to the Human Genome
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Search of human proteins with 42476085

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens]
         (70 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens]        149   6e-37
gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]          123   3e-29
gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]          123   3e-29
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]            32   0.11 
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]       32   0.11 
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            31   0.24 
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    31   0.24 
gi|157364939 phosphodiesterase 6C [Homo sapiens]                       30   0.41 
gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]            30   0.53 
gi|11277468 CD27-binding (Siva) protein isoform 1 [Homo sapiens]       30   0.53 
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...    29   0.70 
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...    29   0.70 
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]             29   0.91 
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]             29   0.91 
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]             29   0.91 
gi|239753274 PREDICTED: hypothetical protein [Homo sapiens]            29   0.91 
gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo ...    29   0.91 
gi|239747844 PREDICTED: hypothetical protein XP_002346445 [Homo ...    29   0.91 
gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo ...    29   0.91 
gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo ...    29   0.91 
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...    29   0.91 
gi|239751010 PREDICTED: hypothetical protein [Homo sapiens]            28   1.2  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      28   1.6  
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    28   1.6  
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ...    28   1.6  
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    28   1.6  
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            28   1.6  
gi|239754100 PREDICTED: hypothetical protein XP_002345880 [Homo ...    28   2.0  
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            28   2.0  
gi|239748649 PREDICTED: hypothetical protein [Homo sapiens]            28   2.0  

>gi|42476085 IKK interacting protein isoform 3.1 [Homo sapiens]
          Length = 70

 Score =  149 bits (375), Expect = 6e-37
 Identities = 70/70 (100%), Positives = 70/70 (100%)

Query: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAC 60
          MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAC
Sbjct: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLAC 60

Query: 61 GRNLKLSWNN 70
          GRNLKLSWNN
Sbjct: 61 GRNLKLSWNN 70


>gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
          Length = 350

 Score =  123 bits (309), Expect = 3e-29
 Identities = 59/59 (100%), Positives = 59/59 (100%)

Query: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
          MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA
Sbjct: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59


>gi|24233517 IKK interacting protein isoform 1 [Homo sapiens]
          Length = 377

 Score =  123 bits (309), Expect = 3e-29
 Identities = 59/59 (100%), Positives = 59/59 (100%)

Query: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59
          MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA
Sbjct: 1  MSEVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLA 59


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 6/58 (10%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGGKTPV------ARSSGGGGWADPRTCLSLLSLGTCL 56
           KS KK   +G  AA       GG  P       A++ GGGG   PR    LL L  CL
Sbjct: 174 KSHKKPRRRGQKAAPAKNSGGGGNKPQKAAAAGAKNRGGGGGKKPRRGRRLLGLLPCL 231


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 9   KSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLS 51
           K GP G P   PGK  + GK  +    G  G  DP  C S+++
Sbjct: 905 KEGPPGDPGL-PGKDGDHGKPGIQGQPGPPGICDPSLCFSVIA 946


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 12 PKGAPAAEPGKRSEGGKTPVARSSGGGGWA 41
          P+G  A   G  + GG  PV R+ GGG WA
Sbjct: 35 PRGPRAGGGGGDAGGGGAPVRRARGGGCWA 64


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
          sapiens]
          Length = 255

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 12 PKGAPAAEPGKRSEGGKTPVARSSGGGGWA 41
          P+G  A   G  + GG  PV R+ GGG WA
Sbjct: 35 PRGPRAGGGGGDAGGGGAPVRRARGGGCWA 64


>gi|157364939 phosphodiesterase 6C [Homo sapiens]
          Length = 858

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 14/31 (45%), Positives = 16/31 (51%)

Query: 19  EPGKRSEGGKTPVARSSGGGGWADPRTCLSL 49
           E  K+ EGG    A  SGGG     +TCL L
Sbjct: 828 EEAKKQEGGAEKAAEDSGGGDDKKSKTCLML 858


>gi|239758117 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 465

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 4   VKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGG 39
           VKSRKK   +G  AA  G+ +  GKT      GGGG
Sbjct: 244 VKSRKKLRQRGQKAAAAGQEAAAGKT-----CGGGG 274


>gi|11277468 CD27-binding (Siva) protein isoform 1 [Homo sapiens]
          Length = 175

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 21/72 (29%), Positives = 27/72 (37%), Gaps = 12/72 (16%)

Query: 9   KSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLS------------LGTCL 56
           K GP GAP A  G+   G    + RS G    ADP    S+               G C 
Sbjct: 72  KPGPTGAPRAARGQMLIGPDGRLIRSLGQASEADPSGVASIACSSCVRAVDGKAVCGQCE 131

Query: 57  GLACGRNLKLSW 68
              CG+ ++  W
Sbjct: 132 RALCGQCVRTCW 143


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
          sapiens]
          Length = 1015

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 10 SGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPR-----TCLSL 49
          SGP+GA    P   S GG TP+  +S  G ++ PR     TCL L
Sbjct: 4  SGPRGAGRRRPP--SGGGDTPITPASLAGCYSAPRRAPLWTCLLL 46


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
          sapiens]
          Length = 1037

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 10 SGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPR-----TCLSL 49
          SGP+GA    P   S GG TP+  +S  G ++ PR     TCL L
Sbjct: 4  SGPRGAGRRRPP--SGGGDTPITPASLAGCYSAPRRAPLWTCLLL 46


>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
          Length = 1740

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 6    SRKKSGPKGAPAAEPGKRSEGGKTPV 31
            S    GP+ APAA+P K S G + PV
Sbjct: 1108 SATSPGPRTAPAAKPEKASAGTRVPV 1133


>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
          Length = 1807

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 6    SRKKSGPKGAPAAEPGKRSEGGKTPV 31
            S    GP+ APAA+P K S G + PV
Sbjct: 1152 SATSPGPRTAPAAKPEKASAGTRVPV 1177


>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
          Length = 1784

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 6    SRKKSGPKGAPAAEPGKRSEGGKTPV 31
            S    GP+ APAA+P K S G + PV
Sbjct: 1152 SATSPGPRTAPAAKPEKASAGTRVPV 1177


>gi|239753274 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 263

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 6  SRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPR 44
          SR+KS P+G P   PG +  G       +SGG    D R
Sbjct: 39 SRRKSAPRGGPGVLPGTKLNG----FCAASGGSRLGDQR 73


>gi|239750867 PREDICTED: hypothetical protein XP_002347588 [Homo
           sapiens]
          Length = 800

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 1/48 (2%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGGKTPVARSSG-GGGWADPRTCLSLLS 51
           K R   GP+G   +  G RS  G    ARS G   GW  P     LLS
Sbjct: 532 KVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLS 579


>gi|239747844 PREDICTED: hypothetical protein XP_002346445 [Homo
          sapiens]
          Length = 263

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 6  SRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPR 44
          SR+KS P+G P   PG +  G       +SGG    D R
Sbjct: 39 SRRKSAPRGGPGVLPGTKLNG----FCAASGGSRLGDQR 73


>gi|239745228 PREDICTED: hypothetical protein XP_002343392 [Homo
           sapiens]
          Length = 488

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 1/48 (2%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGGKTPVARSSG-GGGWADPRTCLSLLS 51
           K R   GP+G   +  G RS  G    ARS G   GW  P     LLS
Sbjct: 404 KVRNPPGPRGGAMSAAGTRSPPGPAESARSRGPRPGWDTPEKGDHLLS 451


>gi|239741651 PREDICTED: hypothetical protein XP_002342270 [Homo
           sapiens]
          Length = 337

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 15/50 (30%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGG---------------KTPVARSSGGGG 39
           KSRKK    G  AA  G +S GG               KT  A+S GGGG
Sbjct: 156 KSRKKPQHWGQKAATAGAKSPGGGGKKPGQEKPAATGEKTRAAKSRGGGG 205



 Score = 26.6 bits (57), Expect = 4.5
 Identities = 15/46 (32%), Positives = 19/46 (41%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLL 50
           KSR   G K    A  G +  GGK P  R    G   + +  L+ L
Sbjct: 252 KSRGGGGIKPQKPAAAGAKIHGGKKPRRRGQSSGNGVEGQNSLAFL 297


>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
          sapiens]
          Length = 1199

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 1/59 (1%)

Query: 1  MSEVKSRKKSGPKG-APAAEPGKRSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGL 58
          + +  S K+SGP G  PA  P K SEG   P A       W   +  +  LS G   GL
Sbjct: 13 LRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQVETLSAGLGPGL 71


>gi|239751010 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/44 (31%), Positives = 20/44 (45%)

Query: 5   KSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTCLS 48
           ++R     +  PA  PG+RS G   P     G GG   P + L+
Sbjct: 166 RARGAPPARRTPARSPGRRSPGWGGPCTPGGGSGGECSPSSRLA 209


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 11  GPKGAPAAEPGKRSEGGKTPVARSSGGGGWADP 43
           G KG   A PG++ EGG   VA   GG G A P
Sbjct: 822 GGKGERGA-PGEKGEGGPPGVAGPPGGSGPAGP 853


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/44 (31%), Positives = 19/44 (43%)

Query: 3   EVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTC 46
           +  +R   G   +  + PG R +G     AR S  GG   P TC
Sbjct: 143 QAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTC 186


>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
           sapiens]
          Length = 209

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/44 (31%), Positives = 19/44 (43%)

Query: 3   EVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTC 46
           +  +R   G   +  + PG R +G     AR S  GG   P TC
Sbjct: 143 QAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTC 186


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/44 (31%), Positives = 19/44 (43%)

Query: 3   EVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTC 46
           +  +R   G   +  + PG R +G     AR S  GG   P TC
Sbjct: 143 QAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTC 186


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 14/44 (31%), Positives = 19/44 (43%)

Query: 3   EVKSRKKSGPKGAPAAEPGKRSEGGKTPVARSSGGGGWADPRTC 46
           +  +R   G   +  + PG R +G     AR S  GG   P TC
Sbjct: 143 QAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGGQPPPLTC 186


>gi|239754100 PREDICTED: hypothetical protein XP_002345880 [Homo
          sapiens]
          Length = 125

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 14/41 (34%), Positives = 20/41 (48%)

Query: 23 RSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLACGRN 63
          RS+  + P   S GG G    ++ L     GT +GL C R+
Sbjct: 23 RSQTSRGPAQPSKGGPGVLGSKSSLGRGPTGTLVGLPCSRS 63


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%)

Query: 10  SGPKGAPA---AEPGKRSEGGKTPVARSSGGGG 39
           SG +  P    A PGK +  G  P AR  GGGG
Sbjct: 376 SGARTLPTPSRARPGKPAPRGSAPPARLRGGGG 408


>gi|239748649 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 125

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 14/41 (34%), Positives = 20/41 (48%)

Query: 23 RSEGGKTPVARSSGGGGWADPRTCLSLLSLGTCLGLACGRN 63
          RS+  + P   S GG G    ++ L     GT +GL C R+
Sbjct: 23 RSQTSRGPAQPSKGGPGVLGSKSSLGRGPTGTLVGLPCSRS 63


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.131    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,529,612
Number of Sequences: 37866
Number of extensions: 155727
Number of successful extensions: 1014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 938
Number of HSP's gapped (non-prelim): 123
length of query: 70
length of database: 18,247,518
effective HSP length: 43
effective length of query: 27
effective length of database: 16,619,280
effective search space: 448720560
effective search space used: 448720560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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