Search of human proteins with 41406089

Search of human proteins with 41406089

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41406089 SRY-box 13 [Homo sapiens]
         (622 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41406089 SRY-box 13 [Homo sapiens]                                1258   0.0  
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   431   e-120
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   431   e-120
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...   361   e-99 
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...   361   e-99 
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   278   1e-74
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...   237   3e-62
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...   232   9e-61
gi|11967991 SRY-box 17 [Homo sapiens]                                 114   2e-25
gi|4507161 SRY-box 11 [Homo sapiens]                                  107   3e-23
gi|4759162 SRY-box 14 [Homo sapiens]                                  107   3e-23
gi|13899269 SRY-box 7 [Homo sapiens]                                  105   1e-22
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      105   2e-22
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        104   2e-22
gi|8924248 SRY-box 18 [Homo sapiens]                                  103   4e-22
gi|5902108 SRY-box 21 [Homo sapiens]                                  103   6e-22
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       100   3e-21
gi|4557853 transcription factor SOX9 [Homo sapiens]                   100   5e-21
gi|5902106 SRY-box 15 [Homo sapiens]                                   99   9e-21
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]              98   2e-20
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]        98   2e-20
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]        97   3e-20
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]        96   8e-20
gi|4507225 sex determining region Y [Homo sapiens]                     95   2e-19
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    85   2e-16
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    85   2e-16
gi|112421108 capicua homolog [Homo sapiens]                            82   1e-15
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]          66   1e-10
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]    65   2e-10
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]    64   3e-10

>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score = 1258 bits (3255), Expect = 0.0
 Identities = 622/622 (100%), Positives = 622/622 (100%)

Query: 1   MSMRSPISAQLALDGVGTMVNCTIKSEEKKEPCHEAPQGSATAAEPQPGDPARASQDSAD 60
           MSMRSPISAQLALDGVGTMVNCTIKSEEKKEPCHEAPQGSATAAEPQPGDPARASQDSAD
Sbjct: 1   MSMRSPISAQLALDGVGTMVNCTIKSEEKKEPCHEAPQGSATAAEPQPGDPARASQDSAD 60

Query: 61  PQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLS 120
           PQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLS
Sbjct: 61  PQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLS 120

Query: 121 SDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAML 180
           SDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAML
Sbjct: 121 SDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAML 180

Query: 181 FEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLP 240
           FEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLP
Sbjct: 181 FEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLP 240

Query: 241 VTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPK 300
           VTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPK
Sbjct: 241 VTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPK 300

Query: 301 APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQL 360
           APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQL
Sbjct: 301 APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQL 360

Query: 361 LHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRN 420
           LHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRN
Sbjct: 361 LHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRN 420

Query: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
           SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL
Sbjct: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480

Query: 481 SRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMS 540
           SRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMS
Sbjct: 481 SRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMS 540

Query: 541 SSDVLYPRAAGMPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYR 600
           SSDVLYPRAAGMPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYR
Sbjct: 541 SSDVLYPRAAGMPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYR 600

Query: 601 YSEDEDSEGEEKSDGELVVLTD 622
           YSEDEDSEGEEKSDGELVVLTD
Sbjct: 601 YSEDEDSEGEEKSDGELVVLTD 622


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  431 bits (1107), Expect = e-120
 Identities = 285/641 (44%), Positives = 365/641 (56%), Gaps = 95/641 (14%)

Query: 58  SADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAI 115
           S  PQ   +G  R S +  S    G+PE ++  +++     +++   +  +N  E  P+I
Sbjct: 94  STSPQKAEEGG-RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSI 152

Query: 116 EKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKN 175
           EKLLS DWK++ L   S    ++KGT ESLAEKE QL+ MI+QL++LR+QLL AH EQK 
Sbjct: 153 EKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKK 212

Query: 176 MAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPP 234
           +AA   EKQ+QQMELA+QQQEQIA+QQQQL+QQQHKINLLQQQIQ Q  +P +MIP FPP
Sbjct: 213 LAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPP 272

Query: 235 SHQPLPVTPDSQLALP--------------IQPIPCK------------PVE----YPLQ 264
             + L         LP              +Q IP              P++    Y  Q
Sbjct: 273 DQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQ 332

Query: 265 LLHSPPAPVVKRPGA-----------------MATHHP----LQEPSQPLNLTAKPK--- 300
           L     +P  K PG                   +T+ P      E +QPLNL+AKPK   
Sbjct: 333 LAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSD 392

Query: 301 --APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358
             +P  P +   P+L+++S    P     P      S     +G+L + DAVTKAIQ+AR
Sbjct: 393 GKSPTSPTSPHMPALRINSGAG-PLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEAR 451

Query: 359 QL---LHSHSGALDGSP---------NTPFRKDLISLDSSP----AKERLEDGCVHPLEE 402
           Q+   L      LDG           N    K+  +L+S       K+  E    H + +
Sbjct: 452 QMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMD 511

Query: 403 AMLSCDMDGSRHFPESR----------NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNS 452
             LS D DGS    ESR          N  HIKRPMNAFMVWAKDERRKILQAFPDMHNS
Sbjct: 512 FNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNS 571

Query: 453 SISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGE 512
           +ISKILGSRWK+MTN EKQPYYEEQARLS+QHLEKYPDYKYKPRPKRTC+V+GK+LR+GE
Sbjct: 572 NISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGE 631

Query: 513 YKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRA---AGMPLAQPLVEH-YVPRSLD 568
           YKA+MR RRQ+ RQ + +  QA Q+ ++++ V+YP A   AGMP      EH  V  S +
Sbjct: 632 YKAIMRNRRQEMRQYFNVGQQA-QIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPE 690

Query: 569 PNMPVIVNTCSLREEGEGTDDRHSVAD--GEMY-RYSEDED 606
           P MPVI +T  ++ E     +     D  GE+Y  Y E+ED
Sbjct: 691 PGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEED 731


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  431 bits (1107), Expect = e-120
 Identities = 285/641 (44%), Positives = 365/641 (56%), Gaps = 95/641 (14%)

Query: 58  SADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAI 115
           S  PQ   +G  R S +  S    G+PE ++  +++     +++   +  +N  E  P+I
Sbjct: 107 STSPQKAEEGG-RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSI 165

Query: 116 EKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKN 175
           EKLLS DWK++ L   S    ++KGT ESLAEKE QL+ MI+QL++LR+QLL AH EQK 
Sbjct: 166 EKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKK 225

Query: 176 MAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPP 234
           +AA   EKQ+QQMELA+QQQEQIA+QQQQL+QQQHKINLLQQQIQ Q  +P +MIP FPP
Sbjct: 226 LAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPP 285

Query: 235 SHQPLPVTPDSQLALP--------------IQPIPCK------------PVE----YPLQ 264
             + L         LP              +Q IP              P++    Y  Q
Sbjct: 286 DQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQ 345

Query: 265 LLHSPPAPVVKRPGA-----------------MATHHP----LQEPSQPLNLTAKPK--- 300
           L     +P  K PG                   +T+ P      E +QPLNL+AKPK   
Sbjct: 346 LAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSD 405

Query: 301 --APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358
             +P  P +   P+L+++S    P     P      S     +G+L + DAVTKAIQ+AR
Sbjct: 406 GKSPTSPTSPHMPALRINSGAG-PLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEAR 464

Query: 359 QL---LHSHSGALDGSP---------NTPFRKDLISLDSSP----AKERLEDGCVHPLEE 402
           Q+   L      LDG           N    K+  +L+S       K+  E    H + +
Sbjct: 465 QMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMD 524

Query: 403 AMLSCDMDGSRHFPESR----------NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNS 452
             LS D DGS    ESR          N  HIKRPMNAFMVWAKDERRKILQAFPDMHNS
Sbjct: 525 FNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNS 584

Query: 453 SISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGE 512
           +ISKILGSRWK+MTN EKQPYYEEQARLS+QHLEKYPDYKYKPRPKRTC+V+GK+LR+GE
Sbjct: 585 NISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGE 644

Query: 513 YKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRA---AGMPLAQPLVEH-YVPRSLD 568
           YKA+MR RRQ+ RQ + +  QA Q+ ++++ V+YP A   AGMP      EH  V  S +
Sbjct: 645 YKAIMRNRRQEMRQYFNVGQQA-QIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPE 703

Query: 569 PNMPVIVNTCSLREEGEGTDDRHSVAD--GEMY-RYSEDED 606
           P MPVI +T  ++ E     +     D  GE+Y  Y E+ED
Sbjct: 704 PGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEED 744


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score =  361 bits (927), Expect = e-99
 Identities = 260/673 (38%), Positives = 341/673 (50%), Gaps = 143/673 (21%)

Query: 82  GSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAK-DV 138
           G+PE ++  +++     ++K   +  R  +E    +EKLLS DWKE+    N+ E   ++
Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177

Query: 139 KGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQI 198
           KGT ESLAEKE QL  MI QL +LR+QLL AH EQK +AA   EKQ+QQM+LARQQQEQI
Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237

Query: 199 AKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQP-IPC 256
           A+QQQQL+QQQHKINLLQQQIQ Q +MP +MIP FP   + L     +Q      P I  
Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297

Query: 257 KPVE-YPLQLLHSPPAPVVKR---------------------PGAMATHHPL-------- 286
           KP + YP+Q + S  A                          PGA     P         
Sbjct: 298 KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV 357

Query: 287 --------------------QEPSQPLNLTAKPKAPELPNTSSSPS-------------L 313
                               +  +QPLNL+++PK  E   + +SP+             L
Sbjct: 358 SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL 417

Query: 314 KMSSCVPRP---------------PSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358
              S +P P                 H   T +L            G+ D V KAIQ+AR
Sbjct: 418 PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR 477

Query: 359 QLLHS--------HSGALDGSPNTPFRKDLISLDSSPAKERLE------------DGCVH 398
           ++               +DG  ++     L S  +   + R E            DG + 
Sbjct: 478 KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG 537

Query: 399 P-------LEEAMLSCDMDGS--------------------RHFPESRNSS----HIKRP 427
           P        E+A  S  M+GS                    R + ++R  +    HIKRP
Sbjct: 538 PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP 597

Query: 428 MNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEK 487
           MNAFMVWAKDERRKILQAFPDMHNS+ISKILGSRWKSM+NQEKQPYYEEQARLS+ HLEK
Sbjct: 598 MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK 657

Query: 488 YPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYP 547
           YP+YKYKPRPKRTCIV+GK+LR+GEYK LMR+RRQ+ RQ + +  Q      + + V+YP
Sbjct: 658 YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP 717

Query: 548 RAAGMPLAQPLVE-----HYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSV-ADGEMYRY 601
            A  M    P  +          S +P++PVI +T  ++ +G        +  + EM  Y
Sbjct: 718 GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY 777

Query: 602 SEDEDSEGEEKSD 614
              +D E + KSD
Sbjct: 778 ---DDYEDDPKSD 787


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score =  361 bits (927), Expect = e-99
 Identities = 260/673 (38%), Positives = 341/673 (50%), Gaps = 143/673 (21%)

Query: 82  GSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAK-DV 138
           G+PE ++  +++     ++K   +  R  +E    +EKLLS DWKE+    N+ E   ++
Sbjct: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180

Query: 139 KGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQI 198
           KGT ESLAEKE QL  MI QL +LR+QLL AH EQK +AA   EKQ+QQM+LARQQQEQI
Sbjct: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240

Query: 199 AKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQP-IPC 256
           A+QQQQL+QQQHKINLLQQQIQ Q +MP +MIP FP   + L     +Q      P I  
Sbjct: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300

Query: 257 KPVE-YPLQLLHSPPAPVVKR---------------------PGAMATHHPL-------- 286
           KP + YP+Q + S  A                          PGA     P         
Sbjct: 301 KPGDNYPVQFIPSTMAAAAASGLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNTAGTV 360

Query: 287 --------------------QEPSQPLNLTAKPKAPELPNTSSSPS-------------L 313
                               +  +QPLNL+++PK  E   + +SP+             L
Sbjct: 361 SPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNL 420

Query: 314 KMSSCVPRP---------------PSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358
              S +P P                 H   T +L            G+ D V KAIQ+AR
Sbjct: 421 PNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAIQEAR 480

Query: 359 QLLHS--------HSGALDGSPNTPFRKDLISLDSSPAKERLE------------DGCVH 398
           ++               +DG  ++     L S  +   + R E            DG + 
Sbjct: 481 KMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLG 540

Query: 399 P-------LEEAMLSCDMDGS--------------------RHFPESRNSS----HIKRP 427
           P        E+A  S  M+GS                    R + ++R  +    HIKRP
Sbjct: 541 PGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRP 600

Query: 428 MNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEK 487
           MNAFMVWAKDERRKILQAFPDMHNS+ISKILGSRWKSM+NQEKQPYYEEQARLS+ HLEK
Sbjct: 601 MNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEK 660

Query: 488 YPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYP 547
           YP+YKYKPRPKRTCIV+GK+LR+GEYK LMR+RRQ+ RQ + +  Q      + + V+YP
Sbjct: 661 YPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYP 720

Query: 548 RAAGMPLAQPLVE-----HYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSV-ADGEMYRY 601
            A  M    P  +          S +P++PVI +T  ++ +G        +  + EM  Y
Sbjct: 721 GAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY 780

Query: 602 SEDEDSEGEEKSD 614
              +D E + KSD
Sbjct: 781 ---DDYEDDPKSD 790


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  278 bits (711), Expect = 1e-74
 Identities = 174/357 (48%), Positives = 217/357 (60%), Gaps = 40/357 (11%)

Query: 288 EPSQPLNLTAKPK-----APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLG 342
           E +QPLNL+AKPK     +P  P +   P+L+++S    P     P      S     +G
Sbjct: 4   EVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAG-PLKASVPAALASPSARVSTIG 62

Query: 343 FLGEGDAVTKAIQDARQL---LHSHSGALDGSP---------NTPFRKDLISLDSSP--- 387
           +L + DAVTKAIQ+ARQ+   L      LDG           N    K+  +L+S     
Sbjct: 63  YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 122

Query: 388 -AKERLEDGCVHPLEEAMLSCDMDGSRHFPESR----------NSSHIKRPMNAFMVWAK 436
             K+  E    H + +  LS D DGS    ESR          N  HIKRPMNAFMVWAK
Sbjct: 123 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK 182

Query: 437 DERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPR 496
           DERRKILQAFPDMHNS+ISKILGSRWK+MTN EKQPYYEEQARLS+QHLEKYPDYKYKPR
Sbjct: 183 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR 242

Query: 497 PKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRA---AGMP 553
           PKRTC+V+GK+LR+GEYKA+MR RRQ+ RQ + +  QA Q+ ++++ V+YP A   AGMP
Sbjct: 243 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQA-QIPIATAGVVYPGAIAMAGMP 301

Query: 554 LAQPLVEHY-VPRSLDPNMPVIVNTCSLREEGEGTDDRHSVAD--GEMY-RYSEDED 606
                 EH  V  S +P MPVI +T  ++ E     +     D  GE+Y  Y E+ED
Sbjct: 302 SPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEED 358


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score =  237 bits (604), Expect = 3e-62
 Identities = 159/393 (40%), Positives = 214/393 (54%), Gaps = 58/393 (14%)

Query: 275 KRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPS-------------LKMSSCVPR 321
           KR  +  T    +  +QPLNL+++PK  E   + +SP+             L   S +P 
Sbjct: 407 KRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPS 466

Query: 322 PPSHG---GPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHS--------HSGALDG 370
           P       G + D+ SS  S  L   G+ D V KAIQ+AR++               +DG
Sbjct: 467 PIGGSLGRGSSLDILSSLNSPAL--FGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDG 524

Query: 371 SPNTPFRKDLISLDSSPAKERLE------------DGCVHP-------LEEAMLSCDMDG 411
             ++     L S  +   + R E            DG + P        E+A     +  
Sbjct: 525 KLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGGATVAE 584

Query: 412 SRHFPESRNSS----HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTN 467
           +R + ++R  +    HIKRPMNAFMVWAKDERRKILQAFPDMHNS+ISKILGSRWKSM+N
Sbjct: 585 ARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSN 644

Query: 468 QEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQS 527
           QEKQPYYEEQARLS+ HLEKYP+YKYKPRPKRTCIV+GK+LR+GEYK LMR+RRQ+ RQ 
Sbjct: 645 QEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQF 704

Query: 528 YVIPPQAGQVQMSSSDVLYPRAAGMPLAQPLVE-----HYVPRSLDPNMPVIVNTCSLRE 582
           + +  Q      + + V+YP A  M    P  +          S +P++PVI +T  ++ 
Sbjct: 705 FTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKT 764

Query: 583 EGEGTDDRHSV-ADGEMYRYSEDEDSEGEEKSD 614
           +G        +  + EM  Y   +D E + KSD
Sbjct: 765 DGGSLAGNEMINGEDEMEMY---DDYEDDPKSD 794



 Score =  162 bits (411), Expect = 7e-40
 Identities = 99/196 (50%), Positives = 128/196 (65%), Gaps = 6/196 (3%)

Query: 82  GSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAK-DV 138
           G+PE ++  +++     ++K   +  R  +E    +EKLLS DWKE+    N+ E   ++
Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177

Query: 139 KGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQI 198
           KGT ESLAEKE QL  MI QL +LR+QLL AH EQK +AA   EKQ+QQM+LARQQQEQI
Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237

Query: 199 AKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQP-IPC 256
           A+QQQQL+QQQHKINLLQQQIQ Q +MP +MIP FP   + L     +Q      P I  
Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297

Query: 257 KPVE-YPLQLLHSPPA 271
           KP + YP+Q + S  A
Sbjct: 298 KPGDNYPVQFIPSTMA 313


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score =  232 bits (591), Expect = 9e-61
 Identities = 163/413 (39%), Positives = 217/413 (52%), Gaps = 78/413 (18%)

Query: 275 KRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPS-------------LKMSSCVPR 321
           KR  +  T    +  +QPLNL+++PK  E   + +SP+             L   S +P 
Sbjct: 420 KRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPS 479

Query: 322 PPSHG---GPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHS--------HSGALDG 370
           P       G + D+ SS  S  L   G+ D V KAIQ+AR++               +DG
Sbjct: 480 PIGGSLGRGSSLDILSSLNSPAL--FGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDG 537

Query: 371 SPNTPFRKDLISLDSSPAKERLE------------DGCVHP-------LEEAMLSCDMDG 411
             ++     L S  +   + R E            DG + P        E+A  S  M+G
Sbjct: 538 KLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNG 597

Query: 412 S--------------------RHFPESRNSS----HIKRPMNAFMVWAKDERRKILQAFP 447
           S                    R + ++R  +    HIKRPMNAFMVWAKDERRKILQAFP
Sbjct: 598 SAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFP 657

Query: 448 DMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKR 507
           DMHNS+ISKILGSRWKSM+NQEKQPYYEEQARLS+ HLEKYP+YKYKPRPKRTCIV+GK+
Sbjct: 658 DMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 717

Query: 508 LRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRAAGMPLAQPLVE-----HY 562
           LR+GEYK LMR+RRQ+ RQ + +  Q      + + V+YP A  M    P  +       
Sbjct: 718 LRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSS 777

Query: 563 VPRSLDPNMPVIVNTCSLREEGEGTDDRHSV-ADGEMYRYSEDEDSEGEEKSD 614
              S +P++PVI +T  ++ +G        +  + EM  Y   +D E + KSD
Sbjct: 778 TSASPEPSLPVIQSTYGMKTDGGSLAGNEMINGEDEMEMY---DDYEDDPKSD 827



 Score =  162 bits (411), Expect = 7e-40
 Identities = 99/196 (50%), Positives = 128/196 (65%), Gaps = 6/196 (3%)

Query: 82  GSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAK-DV 138
           G+PE ++  +++     ++K   +  R  +E    +EKLLS DWKE+    N+ E   ++
Sbjct: 131 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 190

Query: 139 KGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQI 198
           KGT ESLAEKE QL  MI QL +LR+QLL AH EQK +AA   EKQ+QQM+LARQQQEQI
Sbjct: 191 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 250

Query: 199 AKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQP-IPC 256
           A+QQQQL+QQQHKINLLQQQIQ Q +MP +MIP FP   + L     +Q      P I  
Sbjct: 251 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 310

Query: 257 KPVE-YPLQLLHSPPA 271
           KP + YP+Q + S  A
Sbjct: 311 KPGDNYPVQFIPSTMA 326


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  114 bits (286), Expect = 2e-25
 Identities = 58/142 (40%), Positives = 87/142 (61%), Gaps = 8/142 (5%)

Query: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
           ++  S I+RPMNAFMVWAKDER+++ Q  PD+HN+ +SK+LG  WK++T  EK+P+ EE 
Sbjct: 62  AKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEA 121

Query: 478 ARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQV 537
            RL  QH++ +P+YKY+PR +R  +   KR+  G    L         Q+  + P+ G+V
Sbjct: 122 ERLRVQHMQDHPNYKYRPR-RRKQVKRLKRVEGGFLHGLAEP------QAAALGPEGGRV 174

Query: 538 QMSSSDVLYPRAAGMPLAQPLV 559
            M    + +P   G P   PL+
Sbjct: 175 AMDGLGLQFPE-QGFPAGPPLL 195


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  107 bits (268), Expect = 3e-23
 Identities = 48/78 (61%), Positives = 58/78 (74%)

Query: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
           S HIKRPMNAFMVW+K ERRKI++  PDMHN+ ISK LG RWK + + EK P+  E  RL
Sbjct: 46  SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105

Query: 481 SRQHLEKYPDYKYKPRPK 498
             +H+  YPDYKY+PR K
Sbjct: 106 RLKHMADYPDYKYRPRKK 123


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  107 bits (268), Expect = 3e-23
 Identities = 47/81 (58%), Positives = 62/81 (76%)

Query: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
           S+ S HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+PY +E 
Sbjct: 2   SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61

Query: 478 ARLSRQHLEKYPDYKYKPRPK 498
            RL  QH++++PDYKY+PR K
Sbjct: 62  KRLRAQHMKEHPDYKYRPRRK 82


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  105 bits (262), Expect = 1e-22
 Identities = 46/89 (51%), Positives = 66/89 (74%), Gaps = 4/89 (4%)

Query: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479
           + S I+RPMNAFMVWAKDER+++    PD+HN+ +SK+LG  WK++T  +K+PY +E  R
Sbjct: 41  SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAER 100

Query: 480 LSRQHLEKYPDYKYKPRPKRTCIVEGKRL 508
           L  QH++ YP+YKY+PR K+    + KRL
Sbjct: 101 LRLQHMQDYPNYKYRPRRKK----QAKRL 125


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  105 bits (261), Expect = 2e-22
 Identities = 46/78 (58%), Positives = 58/78 (74%)

Query: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
           S HIKRPMNAFMVW++ ERRKI+  +PDMHN+ ISK LG RW+ + + EK P+  E  RL
Sbjct: 37  SGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERL 96

Query: 481 SRQHLEKYPDYKYKPRPK 498
             +H+  YPDYKY+PR K
Sbjct: 97  RLKHMADYPDYKYRPRKK 114


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  104 bits (260), Expect = 2e-22
 Identities = 46/78 (58%), Positives = 58/78 (74%)

Query: 421 SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL 480
           S HIKRPMNAFMVW++ ERRKI++  PDMHN+ ISK LG RWK + + +K P+  E  RL
Sbjct: 56  SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERL 115

Query: 481 SRQHLEKYPDYKYKPRPK 498
             +H+  YPDYKY+PR K
Sbjct: 116 RLKHMADYPDYKYRPRKK 133


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  103 bits (258), Expect = 4e-22
 Identities = 44/83 (53%), Positives = 62/83 (74%)

Query: 417 ESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEE 476
           ++ + S I+RPMNAFMVWAKDER+++ Q  PD+HN+ +SK+LG  WK +   EK+P+ EE
Sbjct: 78  QAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEE 137

Query: 477 QARLSRQHLEKYPDYKYKPRPKR 499
             RL  QHL  +P+YKY+PR K+
Sbjct: 138 AERLRVQHLRDHPNYKYRPRRKK 160


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score =  103 bits (256), Expect = 6e-22
 Identities = 44/81 (54%), Positives = 60/81 (74%)

Query: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
           S+   H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +T  EK+P+ +E 
Sbjct: 2   SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61

Query: 478 ARLSRQHLEKYPDYKYKPRPK 498
            RL   H++++PDYKY+PR K
Sbjct: 62  KRLRAMHMKEHPDYKYRPRRK 82


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  100 bits (250), Expect = 3e-21
 Identities = 43/85 (50%), Positives = 61/85 (71%)

Query: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479
           N   +KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK M+  EK+P+ +E  R
Sbjct: 47  NQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKR 106

Query: 480 LSRQHLEKYPDYKYKPRPKRTCIVE 504
           L   H++++PDYKY+PR K   +++
Sbjct: 107 LRALHMKEHPDYKYRPRRKTKTLLK 131


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score =  100 bits (248), Expect = 5e-21
 Identities = 41/83 (49%), Positives = 59/83 (71%)

Query: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
           S+N  H+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ +   EK+P+ EE 
Sbjct: 99  SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158

Query: 478 ARLSRQHLEKYPDYKYKPRPKRT 500
            RL  QH + +PDYKY+PR +++
Sbjct: 159 ERLRVQHKKDHPDYKYQPRRRKS 181


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score = 99.4 bits (246), Expect = 9e-21
 Identities = 46/88 (52%), Positives = 59/88 (67%)

Query: 411 GSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEK 470
           GS   P +     +KRPMNAFMVW+  +RR++ Q  P MHNS ISK LG++WK +   EK
Sbjct: 36  GSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEK 95

Query: 471 QPYYEEQARLSRQHLEKYPDYKYKPRPK 498
           +P+ EE  RL  +HL  YPDYKY+PR K
Sbjct: 96  RPFVEEAKRLRARHLRDYPDYKYRPRRK 123


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 41/88 (46%), Positives = 62/88 (70%)

Query: 417 ESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEE 476
           +  +   +KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E
Sbjct: 34  QKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDE 93

Query: 477 QARLSRQHLEKYPDYKYKPRPKRTCIVE 504
             RL   H++++PDYKY+PR K   +++
Sbjct: 94  AKRLRALHMKEHPDYKYRPRRKTKTLMK 121


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 42/85 (49%), Positives = 61/85 (71%)

Query: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479
           +   +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +T+ EK+P+ +E  R
Sbjct: 135 DQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKR 194

Query: 480 LSRQHLEKYPDYKYKPRPKRTCIVE 504
           L   H+++YPDYKY+PR K   +++
Sbjct: 195 LRAVHMKEYPDYKYRPRRKTKTLLK 219


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 39/82 (47%), Positives = 58/82 (70%)

Query: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
           S++  H+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ +   +K+P+ EE 
Sbjct: 98  SKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEA 157

Query: 478 ARLSRQHLEKYPDYKYKPRPKR 499
            RL  QH + +PDYKY+PR ++
Sbjct: 158 ERLRMQHKKDHPDYKYQPRRRK 179


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score = 96.3 bits (238), Expect = 8e-20
 Identities = 39/78 (50%), Positives = 57/78 (73%)

Query: 423 HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSR 482
           H+KRPMNAFMVWA+  RRK+   +P +HN+ +SK LG  W+ ++  EK+P+ EE  RL  
Sbjct: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160

Query: 483 QHLEKYPDYKYKPRPKRT 500
           QH + +PDYKY+PR +++
Sbjct: 161 QHKKDHPDYKYQPRRRKS 178


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 41/75 (54%), Positives = 55/75 (73%)

Query: 424 IKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQ 483
           +KRPMNAF+VW++D+RRK+    P M NS ISK LG +WK +T  EK P+++E  +L   
Sbjct: 60  VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119

Query: 484 HLEKYPDYKYKPRPK 498
           H EKYP+YKY+PR K
Sbjct: 120 HREKYPNYKYRPRRK 134


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 40/95 (42%), Positives = 60/95 (63%), Gaps = 8/95 (8%)

Query: 415 FPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYY 474
           F + RN  H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  ++ ++K+PYY
Sbjct: 329 FSKDRNG-HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYY 387

Query: 475 EEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLR 509
           +E  ++  +H E++P + Y+PRP       GKR R
Sbjct: 388 DEAQKIKEKHREEFPGWVYQPRP-------GKRKR 415


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 40/95 (42%), Positives = 60/95 (63%), Gaps = 8/95 (8%)

Query: 415 FPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYY 474
           F + RN  H+KRPMNAFMVWA+  R  + +A P  +N+ IS  LG  W  ++ ++K+PYY
Sbjct: 329 FSKDRNG-HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYY 387

Query: 475 EEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLR 509
           +E  ++  +H E++P + Y+PRP       GKR R
Sbjct: 388 DEAQKIKEKHREEFPGWVYQPRP-------GKRKR 415


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 69/266 (25%), Positives = 108/266 (40%), Gaps = 27/266 (10%)

Query: 285 PLQEPSQPLNLTAKPKAPELP-------NTSSSPSLKMSSCVPRPPSHGG-------PTR 330
           P   PSQP + + +P   + P       N S  P+   +    RPP   G       P  
Sbjct: 42  PFLAPSQP-DPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGA 100

Query: 331 DLQSSP---PSLPLGFLGEGDAVTKAIQD------ARQLLHSHSGALDGSPNTPFRKDLI 381
               SP   P  PLG +  G       ++          L S + +             I
Sbjct: 101 TCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEI 160

Query: 382 SLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWAKDERRK 441
            L   P K R +     P E    S + DG    P  R   HI+RPMNAFM+++K  R  
Sbjct: 161 QLPLPPGKRRTQSLSALPKERDS-SSEKDGRS--PNKREKDHIRRPMNAFMIFSKRHRAL 217

Query: 442 ILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTC 501
           + Q  P+  N ++SKILG  W ++  +EKQ Y++   ++   H + +PD+K+  + ++  
Sbjct: 218 VHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277

Query: 502 IVEGKRLRVGEYKALMRTRRQDARQS 527
             E K   +G       TR +   ++
Sbjct: 278 SSEAKPTSLGLAGGHKETRERSMSET 303



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 17/73 (23%)

Query: 37   PQGSATAAEPQPG-----DPARASQDSADPQA-------PAQGNFRGSWDCSSPEGNGSP 84
            P G+A A  P P      DP   S DS   QA       P  G  +  W     EG   P
Sbjct: 1540 PTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGW-----EGAPQP 1594

Query: 85   EPKRPGVSEAASG 97
             P  PG S AA+G
Sbjct: 1595 SPPPPGPSTAATG 1607


>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
          Length = 588

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 85/341 (24%), Positives = 136/341 (39%), Gaps = 61/341 (17%)

Query: 225 PYVMIPAFP-PSHQPLPVTPDS-----QLALPIQPIPC----KPVEYPLQLLHSPPAPVV 274
           P++MIP    P     P++P       Q+  P+  +P     K    P     S   PVV
Sbjct: 123 PFLMIPDLSSPYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAHLSNKVPVV 182

Query: 275 KRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQS 334
           + P  M   HPL   +  +  +    +P  P T  SP +   + +PRPP     +     
Sbjct: 183 QHPHHM---HPL---TPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYYPL 236

Query: 335 SPPSL-----PLGFLGEGDAVTKAIQDARQLLHS--HSGALDGSPNTPFRKDLISLDSS- 386
           SP ++     PLG+L         +    Q ++S    G     P       + SL SS 
Sbjct: 237 SPGAVGQIPHPLGWL---------VPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSR 287

Query: 387 -------PAKERLE-DGCVHPL--------EEAMLSCDMDGSRHFP-----ESRNSSHIK 425
                  PA   L   G  HP         E A  S     S   P     E     H+K
Sbjct: 288 FSPHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVK 347

Query: 426 RPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHL 485
           +P+NAFM++ K+ R K++       +++I++ILG +W +++ +E+  YYE   +  + H 
Sbjct: 348 KPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHS 407

Query: 486 EKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQ 526
           + YP +  +          GK+ +    K L +T+ Q   Q
Sbjct: 408 QLYPTWSARDN-------YGKKKKRKREKQLSQTQSQQQVQ 441



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 76/315 (24%), Positives = 112/315 (35%), Gaps = 72/315 (22%)

Query: 46  PQPGDPARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFN 105
           P  G P  A       Q PA  +   +    SP      E K+P V +  +     + + 
Sbjct: 301 PTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEEKKPHVKKPLNAF---MLYM 357

Query: 106 RNLKEVVPAIEKLLSSDWKERFLGRNSME-AKDVKGTQESLAEKELQLLVMIHQLSTLRD 164
           + ++  V A   L  S    + LGR     +++ +     LA KE QL            
Sbjct: 358 KEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQL----------HS 407

Query: 165 QLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNM 224
           QL    S + N       K+++Q+    Q Q+Q+ + +  L  +  K             
Sbjct: 408 QLYPTWSARDNYGKKKKRKREKQLSQT-QSQQQVQEAEGALASKSKK------------- 453

Query: 225 PYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQ----LLHSP--PAPVVKRPG 278
                    P  Q LP              P KP + P      +L SP  P+  +  P 
Sbjct: 454 ---------PCVQYLP--------------PEKPCDSPASSHGSMLDSPATPSAALASPA 490

Query: 279 AMATHHPLQEPSQPLNLTAKPK----------APELPNTSSSPSLKMSSCVP---RPPSH 325
           A A  H   E +QPL+LT KP+          A      ++S S +M S  P   RP   
Sbjct: 491 APAATH--SEQAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQPPLLSRPLPL 548

Query: 326 GGPTRDLQSSPPSLP 340
           G     L +SPPS P
Sbjct: 549 GSMPTALLASPPSFP 563


>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
          Length = 455

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 68/296 (22%), Positives = 115/296 (38%), Gaps = 67/296 (22%)

Query: 198 IAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCK 257
           I   +  ++Q  H ++ L   I   N  +   P  PP H P  V P + +  P  P    
Sbjct: 160 IVSNKVPVVQHPHHVHPLTPLITYSNEHFT--PGNPPPHLPADVDPKTGIPRPPHPPDIS 217

Query: 258 PVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSS 317
           P  YPL      P  V + P      HPL    QP+             T+ + +  MS 
Sbjct: 218 PY-YPLS-----PGTVGQIP------HPLGWQGQPVYPITTGGFRHPYPTALTVNASMSR 265

Query: 318 CVPR--PPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALDGSPNTP 375
             P   PP H   T  +    P++          VT  ++  ++   S  G+L  S +  
Sbjct: 266 FPPHMVPPHHTLHTTGIPH--PAI----------VTPTVK--QESSQSDVGSLHSSKHQD 311

Query: 376 FRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWA 435
            +K+                                     E +   HIK+P+NAFM++ 
Sbjct: 312 SKKE-------------------------------------EEKKKPHIKKPLNAFMLYM 334

Query: 436 KDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDY 491
           K+ R K++       +++I++ILG RW +++ +E+  YYE   +  + H++ YP +
Sbjct: 335 KEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 390


>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
          Length = 602

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 72/336 (21%), Positives = 130/336 (38%), Gaps = 65/336 (19%)

Query: 161 TLRDQLLTAHSEQK----NMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQ 216
           T+  Q+   + + K    ++ A   + +Q   +        I   +  ++Q  H ++ L 
Sbjct: 142 TIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLT 201

Query: 217 QQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKR 276
             I   N  +   P  PP H P  V P + +  P  P    P  YPL      P  V + 
Sbjct: 202 PLITYSNEHFT--PGNPPPHLPADVDPKTGIPRPPHPPDISPY-YPLS-----PGTVGQI 253

Query: 277 PGAMATHHPLQ-EPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSS 335
           P  +    P Q +P  P+  T   + P         +L +++ + R P H  P       
Sbjct: 254 PHPLGWLVPQQGQPVYPIT-TGGFRHPY------PTALTVNASMSRFPPHMVPPH----- 301

Query: 336 PPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDG 395
                                       H+    G P+       +  +SS +    + G
Sbjct: 302 ----------------------------HTLHTTGIPHPAIVTPTVKQESSQS----DVG 329

Query: 396 CVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSIS 455
            +H       S   D  +   E +   HIK+P+NAFM++ K+ R K++       +++I+
Sbjct: 330 SLHS------SKHQDSKKE--EEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAIN 381

Query: 456 KILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDY 491
           +ILG RW +++ +E+  YYE   +  + H++ YP +
Sbjct: 382 QILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 417


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,205,459
Number of Sequences: 37866
Number of extensions: 1610456
Number of successful extensions: 15061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 293
Number of HSP's successfully gapped in prelim test: 722
Number of HSP's that attempted gapping in prelim test: 8720
Number of HSP's gapped (non-prelim): 3942
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.