Guide to the Human Genome
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Search of human proteins with 40255272

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40255272 xin actin-binding repeat containing 1 [Homo
sapiens]
         (1843 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]     3712   0.0  
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho...   417   e-116
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   5e-13
gi|150170670 piccolo isoform 2 [Homo sapiens]                          64   1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          64   1e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    63   2e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     61   1e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   3e-08
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              59   3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          58   7e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          58   7e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          58   7e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   4e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    56   4e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   6e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    55   6e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               55   8e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              55   8e-07
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    54   1e-06
gi|33286436 gametogenetin [Homo sapiens]                               53   2e-06
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    53   3e-06
gi|112421108 capicua homolog [Homo sapiens]                            53   3e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   4e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   4e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         52   7e-06
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]    52   7e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    52   7e-06
gi|188536004 zinc finger protein 469 [Homo sapiens]                    51   9e-06
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         51   9e-06
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    51   1e-05

>gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]
          Length = 1843

 Score = 3712 bits (9627), Expect = 0.0
 Identities = 1843/1843 (100%), Positives = 1843/1843 (100%)

Query: 1    MADTQTQVAPTPTMRMATAEDLPLPPPPALEDLPLPPPKESFSKFHQQRQASELRRLYRH 60
            MADTQTQVAPTPTMRMATAEDLPLPPPPALEDLPLPPPKESFSKFHQQRQASELRRLYRH
Sbjct: 1    MADTQTQVAPTPTMRMATAEDLPLPPPPALEDLPLPPPKESFSKFHQQRQASELRRLYRH 60

Query: 61   IHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGEHERPAAKEPVLC 120
            IHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGEHERPAAKEPVLC
Sbjct: 61   IHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGEHERPAAKEPVLC 120

Query: 121  GDVQATSRKFEEGSFANSTDQEPTRPQPGGGDVRAARWLFETKPLDELTGQAKELEATVR 180
            GDVQATSRKFEEGSFANSTDQEPTRPQPGGGDVRAARWLFETKPLDELTGQAKELEATVR
Sbjct: 121  GDVQATSRKFEEGSFANSTDQEPTRPQPGGGDVRAARWLFETKPLDELTGQAKELEATVR 180

Query: 181  EPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVKKTVKLFQTEPL 240
            EPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVKKTVKLFQTEPL
Sbjct: 181  EPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVKKTVKLFQTEPL 240

Query: 241  CAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETRPLDAINQDPSQVRVIRGISLEEGA 300
            CAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETRPLDAINQDPSQVRVIRGISLEEGA
Sbjct: 241  CAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETRPLDAINQDPSQVRVIRGISLEEGA 300

Query: 301  RPDVSATRWIFETQPLDAIREILVDEKDFQPSPDLIPPGPDVQQQQHLFETRALDTLKGD 360
            RPDVSATRWIFETQPLDAIREILVDEKDFQPSPDLIPPGPDVQQQQHLFETRALDTLKGD
Sbjct: 301  RPDVSATRWIFETQPLDAIREILVDEKDFQPSPDLIPPGPDVQQQQHLFETRALDTLKGD 360

Query: 361  EEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVDPQDGEGHLSSDSSS 420
            EEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVDPQDGEGHLSSDSSS
Sbjct: 361  EEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVDPQDGEGHLSSDSSS 420

Query: 421  ALPFSQSAPQRDELKGDVKTFKNLFETLPLDSIGQGEVLAHGSPSREEGTDSAGQAQGIG 480
            ALPFSQSAPQRDELKGDVKTFKNLFETLPLDSIGQGEVLAHGSPSREEGTDSAGQAQGIG
Sbjct: 421  ALPFSQSAPQRDELKGDVKTFKNLFETLPLDSIGQGEVLAHGSPSREEGTDSAGQAQGIG 480

Query: 481  SPVYAMQDSKGRLHALTSVSREQIVGGDVQGYRWMFETQPLDQLGRSPSTIDVVRGITRQ 540
            SPVYAMQDSKGRLHALTSVSREQIVGGDVQGYRWMFETQPLDQLGRSPSTIDVVRGITRQ
Sbjct: 481  SPVYAMQDSKGRLHALTSVSREQIVGGDVQGYRWMFETQPLDQLGRSPSTIDVVRGITRQ 540

Query: 541  EVVAGDVGTARWLFETQPLEMIHQREQQERQKEEGKSQGDPQPEAPPKGDVQTIRWLFET 600
            EVVAGDVGTARWLFETQPLEMIHQREQQERQKEEGKSQGDPQPEAPPKGDVQTIRWLFET
Sbjct: 541  EVVAGDVGTARWLFETQPLEMIHQREQQERQKEEGKSQGDPQPEAPPKGDVQTIRWLFET 600

Query: 601  CPMSELAEKQGSEVTDPTAKAEAQSCTWMFKPQPVDRPVGSREQHLQVSQVPAGERQTDR 660
            CPMSELAEKQGSEVTDPTAKAEAQSCTWMFKPQPVDRPVGSREQHLQVSQVPAGERQTDR
Sbjct: 601  CPMSELAEKQGSEVTDPTAKAEAQSCTWMFKPQPVDRPVGSREQHLQVSQVPAGERQTDR 660

Query: 661  HVFETEPLQASGRPCGRRPVRYCSRVEIPSGQVSRQKEVFQALEAGKKEEQEPRVIAGSI 720
            HVFETEPLQASGRPCGRRPVRYCSRVEIPSGQVSRQKEVFQALEAGKKEEQEPRVIAGSI
Sbjct: 661  HVFETEPLQASGRPCGRRPVRYCSRVEIPSGQVSRQKEVFQALEAGKKEEQEPRVIAGSI 720

Query: 721  PAGSVHKFTWLFENCPMGSLAAESIQGGNLLEEQPMSPSGNRMQESQETAAEGTLRTLHA 780
            PAGSVHKFTWLFENCPMGSLAAESIQGGNLLEEQPMSPSGNRMQESQETAAEGTLRTLHA
Sbjct: 721  PAGSVHKFTWLFENCPMGSLAAESIQGGNLLEEQPMSPSGNRMQESQETAAEGTLRTLHA 780

Query: 781  TPGILHHGGILMEARGPGELCLAKYVLSGTGQGHPYIRKEELVSGELPRIICQVLRRPDV 840
            TPGILHHGGILMEARGPGELCLAKYVLSGTGQGHPYIRKEELVSGELPRIICQVLRRPDV
Sbjct: 781  TPGILHHGGILMEARGPGELCLAKYVLSGTGQGHPYIRKEELVSGELPRIICQVLRRPDV 840

Query: 841  DQQGLLVQEDPTGQLQLKPLRLPTPGSSGNIEDMDPELQQLLACGLGTSVARTGLVMQET 900
            DQQGLLVQEDPTGQLQLKPLRLPTPGSSGNIEDMDPELQQLLACGLGTSVARTGLVMQET
Sbjct: 841  DQQGLLVQEDPTGQLQLKPLRLPTPGSSGNIEDMDPELQQLLACGLGTSVARTGLVMQET 900

Query: 901  EQGLVALTAYSLQPRLTSKASERSSVQLLASCIDKGDLSGLHSLRWEPPADPSPVPASEG 960
            EQGLVALTAYSLQPRLTSKASERSSVQLLASCIDKGDLSGLHSLRWEPPADPSPVPASEG
Sbjct: 901  EQGLVALTAYSLQPRLTSKASERSSVQLLASCIDKGDLSGLHSLRWEPPADPSPVPASEG 960

Query: 961  AQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQ 1020
            AQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQ
Sbjct: 961  AQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQ 1020

Query: 1021 EDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGP 1080
            EDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGP
Sbjct: 1021 EDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGP 1080

Query: 1081 TPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQD 1140
            TPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQD
Sbjct: 1081 TPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQD 1140

Query: 1141 GIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCT 1200
            GIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCT
Sbjct: 1141 GIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCT 1200

Query: 1201 QMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL 1260
            QMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL
Sbjct: 1201 QMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL 1260

Query: 1261 PAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPP 1320
            PAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPP
Sbjct: 1261 PAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPP 1320

Query: 1321 KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTV 1380
            KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTV
Sbjct: 1321 KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTV 1380

Query: 1381 DQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQW 1440
            DQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQW
Sbjct: 1381 DQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQW 1440

Query: 1441 GPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEA 1500
            GPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEA
Sbjct: 1441 GPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEA 1500

Query: 1501 VPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALSS 1560
            VPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALSS
Sbjct: 1501 VPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALSS 1560

Query: 1561 MSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKNQAKVECHTE 1620
            MSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKNQAKVECHTE
Sbjct: 1561 MSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKNQAKVECHTE 1620

Query: 1621 AQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATR 1680
            AQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATR
Sbjct: 1621 AQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATR 1680

Query: 1681 KPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASP 1740
            KPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASP
Sbjct: 1681 KPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASP 1740

Query: 1741 LPRGWQKSVLELQTGPGSSQHYGAMRTVTEQYEEVDQFGNTVLMSSTTVTEQAEPPRNPG 1800
            LPRGWQKSVLELQTGPGSSQHYGAMRTVTEQYEEVDQFGNTVLMSSTTVTEQAEPPRNPG
Sbjct: 1741 LPRGWQKSVLELQTGPGSSQHYGAMRTVTEQYEEVDQFGNTVLMSSTTVTEQAEPPRNPG 1800

Query: 1801 SHLGLHASPLLRQFLHSPAGFSSDLTEAETVQVSCSYSQPAAQ 1843
            SHLGLHASPLLRQFLHSPAGFSSDLTEAETVQVSCSYSQPAAQ
Sbjct: 1801 SHLGLHASPLLRQFLHSPAGFSSDLTEAETVQVSCSYSQPAAQ 1843


>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
            sapiens]
          Length = 3549

 Score =  417 bits (1073), Expect = e-116
 Identities = 280/846 (33%), Positives = 446/846 (52%), Gaps = 124/846 (14%)

Query: 4    TQTQVAPTPTMRMATAEDLPLPPPPALE------------DLPLPP-----PKESFSKFH 46
            T + +A          E+ P PPP  L+            +LP PP     PK+ +SK  
Sbjct: 434  TSSTLAQINATSSGMTEEFPPPPPDVLQTSVDVTAFSQSPELPSPPRRLPVPKDVYSK-- 491

Query: 47   QQRQASELRRLYRHIHPELRKNLAEAVAEDLAEVLGSE---------------------- 84
             QR   EL RLY+HIHPELRKNL +    +++E++ S+                      
Sbjct: 492  -QRNLYELNRLYKHIHPELRKNLEKDYISEVSEIVSSQMNSGSSVSADVQQARYVFENTN 550

Query: 85   -----------------EPTEGDVQCMRWIFENWRLDAI-------GEHERPAAKEPVLC 120
                             E  +G+VQ +RWIFEN  LD+I       G+  R  A + ++ 
Sbjct: 551  DSSQKDLNSEREYLEWDEILKGEVQSIRWIFENQPLDSINNGSPDEGDISRGIADQEIIA 610

Query: 121  G-DVQATSRKFEE------GSFANSTDQEPTR-PQPGGGDVRAARWLFETKPLDELTGQA 172
            G DV+ T+  FE       G++++ T +   + P+   GDV  ARW+FET+PLD +    
Sbjct: 611  GGDVKYTTWMFETQPIDTLGAYSSDTVENAEKIPELARGDVCTARWMFETRPLDSMNKMH 670

Query: 173  KELE---ATVREPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVK 229
            +  E    T+ +    GDV+  R +FET+ LD+LG   S+ E   L+LRSE++E+KG+VK
Sbjct: 671  QSQEESAVTISKDITGGDVKTVRYMFETQHLDQLGQLHSVDEVHLLQLRSELKEIKGNVK 730

Query: 230  KTVKLFQTEPLCAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETRPLDAINQDPSQVR 289
            +++K F+T+PL  I+D  G + E+K   RE+++   VR+ARW+FET+PLD IN+D ++++
Sbjct: 731  RSIKCFETQPLYVIRDGSGQMLEIKTVHREDVEKGDVRTARWMFETQPLDTINKDITEIK 790

Query: 290  VIRGISLEEGARPDVSATRWIFETQPLDAIREILVDEKDFQPSPDLIPPGPDVQQQQHLF 349
            V+RGIS+EE  +  VS  +W+FETQPL+ I+E    E+       +I  G DV ++  +F
Sbjct: 791  VVRGISMEENVKGGVSKAKWLFETQPLEKIKE---SEEVIIEKEKII--GTDVSRKCWMF 845

Query: 350  ETRALDTLKGDEEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVDPQD 409
            ET+ LD LK  E   A++  +EE++ GDV++T  LFET P++A +D   +G LQ++   +
Sbjct: 846  ETQPLDILK--EVPDADSLQREEIIGGDVQTTKHLFETLPIEALKDSPDIGKLQKITASE 903

Query: 410  GE-------------GHLSSDSSSALPFSQSAPQRDELKGDVKTFKNLFETLPLDSIGQG 456
             E               L         ++++    +  +GDVK + ++FE+  L      
Sbjct: 904  EEKGDVRHQKWIFETQPLEDIRKDKKEYTRTVKLEEVDRGDVKNYTHIFESNNLIKFDAS 963

Query: 457  EVLAHGSPSREEGTDSAGQAQGIGSPVYAMQDSKGRLHALTSVSREQIVGGDVQGYRWMF 516
              +     +R  G     ++    +P+YA+QD  G+ H + +V +E+IV GDV+  RW+F
Sbjct: 964  HKIEVEGVTR--GAVELNKSLFETTPLYAIQDPLGKYHQVKTVQQEEIVRGDVRSCRWLF 1021

Query: 517  ETQPLDQLGRSPSTIDVVRGITRQEVVAGDVGTARWLFETQPLEMIHQREQQERQKEEGK 576
            ET+P+DQ   S     ++RGI+ QE+  G+V +A+WLFETQPL+ I  +   + ++ E K
Sbjct: 1022 ETRPIDQFDESIHKFQIIRGISAQEIQTGNVKSAKWLFETQPLDSI--KYFSDVEETESK 1079

Query: 577  SQGDPQPEAPPKGDVQTIRWLFETCPMSELAEKQG-SEVTDPTAKAEAQSCTWMFKPQPV 635
            ++   Q     KGDV+T +WLFET PM  L EK      ++   K + ++CTW+F+ QP+
Sbjct: 1080 TE---QTRDIVKGDVKTCKWLFETQPMESLYEKVSLMTSSEEIHKGDVKTCTWLFETQPL 1136

Query: 636  DRPVGSRE-----QHLQVSQVPAGERQTDRHVFETEPLQA-SGRPCGR-RPVRYCSRVEI 688
            D      E     Q ++  ++  G+ +T   +FETE L +  G      +PV     ++I
Sbjct: 1137 DTIKDDSETAVKLQTVKQEEIQGGDVRTACFLFETENLDSIQGEEVKEIKPV----EMDI 1192

Query: 689  PSGQVSRQKEVF--QALEAGKKEEQE-----PRVIAGSIPAGSVHKFTWLFENCPMGSLA 741
             +G VS  +  F  Q+L++     +E       +    I  G+V    WLFEN P+  + 
Sbjct: 1193 QAGDVSSMRYKFENQSLDSISSSSEEVLKKIKTLKTEDIQKGNVLNCRWLFENQPIDKI- 1251

Query: 742  AESIQG 747
             ES +G
Sbjct: 1252 KESQEG 1257



 Score =  297 bits (761), Expect = 6e-80
 Identities = 277/1010 (27%), Positives = 437/1010 (43%), Gaps = 196/1010 (19%)

Query: 71   EAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGE--HERPAAKEPVLCGDVQATSR 128
            E + E    ++  E+    DV    W+FE   LD + E        +E ++ GDVQ T  
Sbjct: 818  EKIKESEEVIIEKEKIIGTDVSRKCWMFETQPLDILKEVPDADSLQREEIIGGDVQTTKH 877

Query: 129  KFEE---GSFANSTD----QEPTRPQPGGGDVRAARWLFETKPLDELTGQAKELEATVR- 180
             FE     +  +S D    Q+ T  +   GDVR  +W+FET+PL+++    KE   TV+ 
Sbjct: 878  LFETLPIEALKDSPDIGKLQKITASEEEKGDVRHQKWIFETQPLEDIRKDKKEYTRTVKL 937

Query: 181  EPAASGDVQGTRMLFETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVKKTVKLFQTEPL 240
            E    GDV+    +FE+  L +  +   ++ +            +G V+    LF+T PL
Sbjct: 938  EEVDRGDVKNYTHIFESNNLIKFDASHKIEVEGVT---------RGAVELNKSLFETTPL 988

Query: 241  CAIQDAEGAIHEVKAACREEIQSNAVRSARWLFETRPLDAINQDPSQVRVIRGISLEEGA 300
             AIQD  G  H+VK   +EEI    VRS RWLFETRP+D  ++   + ++IRGIS +E  
Sbjct: 989  YAIQDPLGKYHQVKTVQQEEIVRGDVRSCRWLFETRPIDQFDESIHKFQIIRGISAQEIQ 1048

Query: 301  RPDVSATRWIFETQPLDAIR---EILVDEKDFQPSPDLIPPGPDVQQQQHLFETRALDTL 357
              +V + +W+FETQPLD+I+   ++   E   + + D++    DV+  + LFET+ +++L
Sbjct: 1049 TGNVKSAKWLFETQPLDSIKYFSDVEETESKTEQTRDIVKG--DVKTCKWLFETQPMESL 1106

Query: 358  KGDEEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVDPQDGEGHLSSD 417
                E  +     EE+  GDV++  WLFET+PLD  +D                     D
Sbjct: 1107 Y---EKVSLMTSSEEIHKGDVKTCTWLFETQPLDTIKD---------------------D 1142

Query: 418  SSSALPFSQSAPQRDELKGDVKTFKNLFETLPLDSIGQGEVLAHGSPSREEGTDSAGQAQ 477
            S +A+   Q+  Q +   GDV+T   LFET  LDSI QGE +    P      +   QA 
Sbjct: 1143 SETAVKL-QTVKQEEIQGGDVRTACFLFETENLDSI-QGEEVKEIKP-----VEMDIQAG 1195

Query: 478  GIGSPVYAMQD---------SKGRLHALTSVSREQIVGGDVQGYRWMFETQPLDQLGRSP 528
             + S  Y  ++         S+  L  + ++  E I  G+V   RW+FE QP+D++  S 
Sbjct: 1196 DVSSMRYKFENQSLDSISSSSEEVLKKIKTLKTEDIQKGNVLNCRWLFENQPIDKIKESQ 1255

Query: 529  STIDVVRGIT-----------------------------------RQEVVAGDVGTARWL 553
               + V+ +T                                    +EV+ GDV + R L
Sbjct: 1256 EGDECVKTVTDIQGGDVRKGCFIFETFSLDEIKEESDYISTKKTITEEVIQGDVKSYRML 1315

Query: 554  FETQPLEMIHQREQQERQKEEGKSQGDPQPEAPPKGDVQTIRWLFETCPMSELAEKQG-- 611
            FETQPL  I  RE    +    K       E    GDV+  RWLFET P+  + + +   
Sbjct: 1316 FETQPLYAIQDREGSYHEVTTVKK------EEVIHGDVRGTRWLFETKPLDSINKSETVY 1369

Query: 612  ---SEVTDPTAKAEAQSCTWMFKPQPVDRPVGSREQHL---QVSQVPAGERQTDRHVFET 665
               S   +   K +  S  + F+ QP+D+   S E H     +  +  G  +T R  FE+
Sbjct: 1370 VIKSVTQEDIQKGDVSSVRYRFETQPLDQI--SEESHNIMPSIDHIQGGNVKTSRQFFES 1427

Query: 666  EPLQASGRPCGRRPVRYCSRVEIPSGQVSRQKEVFQALEA------GKKEEQEPRVIAGS 719
            E    +        +R  S  EI  G V     +F+          G + E    V    
Sbjct: 1428 ENFDKNNY------IRTVSVNEIQKGNVKTSTWLFETHTMDELRGEGLEYENIKTVTQED 1481

Query: 720  IPAGSVHKFTWLFENCPMGSLAAESIQGGNLLEEQPMSPSGNR----------MQESQET 769
            +  G V +  WLFEN    S+  E+ +G   + ++ + PS  +          + E  ET
Sbjct: 1482 VQKGDVKQAVWLFENRTFDSIM-EAHKGITKMTKEEIPPSDVKTTTWLFETTPLHEFNET 1540

Query: 770  AAEG----------TLRTLHATPGILHHGGILMEARGPGELCLAKYVLSGTGQGHPYIRK 819
              E           TL  L++   ++   GI++EA   G++ +AKY L    Q  P I+K
Sbjct: 1541 RVEKIEIIGKSIKETLEDLYSQK-VIQAPGIIIEADEIGDVRMAKYKLMN--QASPEIQK 1597

Query: 820  EELVSGELPRIICQVLRRPDVDQQGLLVQEDPTGQLQLKPLRLPTPGSSGNIE------- 872
            EE++  +L  I+  +L + D  ++ +L+ E+  G + L   +L    +  + E       
Sbjct: 1598 EEIIRADLRNIMVNLLSKRDCTEREILISEEEKGNVNLTKTQLLNRSTEFHAEKEEIVKG 1657

Query: 873  DMDPELQQLLACGLGTSVARTGLVMQETEQGLVALTAYSL-------------------- 912
            D+   ++ L +        + G+++QE E+G + +T Y L                    
Sbjct: 1658 DVQQAIKNLFS---EERSVKKGILIQEDEKGDINMTIYCLLHENDGDTIEREEVIGGDVK 1714

Query: 913  ---------------QPRLTSKASERSSVQLLASCIDKGDLSGLHSLRWE 947
                             R    ASER +VQ   +CI+ G L  L  L  E
Sbjct: 1715 RTIHNLLSSTSNNKISERAKIDASERGNVQFFTTCIEAGALDYLKQLHTE 1764



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 118/513 (23%), Positives = 209/513 (40%), Gaps = 66/513 (12%)

Query: 84   EEPTEGDVQCMRWIFENWRLDAIGEHE-----RPAAKEPVLCGDVQATSRKFEEGSFANS 138
            EE   GDV+  RW+FE   LD+I + E     +   +E +  GDV +   +FE       
Sbjct: 1340 EEVIHGDVRGTRWLFETKPLDSINKSETVYVIKSVTQEDIQKGDVSSVRYRFETQPLDQI 1399

Query: 139  TDQE----PTRPQPGGGDVRAARWLFETKPLDELTGQAKELEATVREPAASGDVQGTRML 194
            +++     P+     GG+V+ +R  FE++  D+       +          G+V+ +  L
Sbjct: 1400 SEESHNIMPSIDHIQGGNVKTSRQFFESENFDK----NNYIRTVSVNEIQKGNVKTSTWL 1455

Query: 195  FETRPLDRLGSRPSLQEQSPLELRSEIQELKGDVKKTVKLFQTEPLCAIQDAEGAIHEVK 254
            FET  +D L       E      + ++Q  KGDVK+ V LF+     +I +A   I ++ 
Sbjct: 1456 FETHTMDELRGEGLEYENIKTVTQEDVQ--KGDVKQAVWLFENRTFDSIMEAHKGITKMT 1513

Query: 255  AACREEIQSNAVRSARWLFETRPLDAINQ------------------DPSQVRVIR--GI 294
               +EEI  + V++  WLFET PL   N+                  D    +VI+  GI
Sbjct: 1514 ---KEEIPPSDVKTTTWLFETTPLHEFNETRVEKIEIIGKSIKETLEDLYSQKVIQAPGI 1570

Query: 295  SLEEGARPDVSATRWIFETQPLDAIREILVDEKDFQPSPDLIPPGPDVQQQQHLFETRA- 353
             +E     DV   ++    Q    I++  +   D +     +    D  +++ L      
Sbjct: 1571 IIEADEIGDVRMAKYKLMNQASPEIQKEEIIRADLRNIMVNLLSKRDCTEREILISEEEK 1630

Query: 354  -------LDTLKGDEEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAFRDKVQVGHLQRVD 406
                      L    E  AE   KEE+V GDV+  +     K L +    V+ G L + D
Sbjct: 1631 GNVNLTKTQLLNRSTEFHAE---KEEIVKGDVQQAI-----KNLFSEERSVKKGILIQED 1682

Query: 407  PQDGEGHLSSDSSSALPFSQSAPQRDELKGDVK-TFKNLFETLPLDSIGQGEVLAHGSPS 465
             + G+ +++           +  + + + GDVK T  NL  +   + I +   +      
Sbjct: 1683 -EKGDINMTIYCLLHENDGDTIEREEVIGGDVKRTIHNLLSSTSNNKISERAKIDASERG 1741

Query: 466  REEGTDSAGQAQGIGSPVYAMQDSKGRLHALTSVSREQIVGGDVQGYRWMFETQPLDQLG 525
              +   +  +A  +        +S   L A      ++I+GGDV+G + +        L 
Sbjct: 1742 NVQFFTTCIEAGALDYLKQLHTESNETLTAKKQEGEKEIIGGDVEGTKLL--------LK 1793

Query: 526  RSPSTIDVVRGITRQEVVAGDVGTARWLFETQP 558
            +  S ++  R ++  +++ GDV     +F T+P
Sbjct: 1794 KRQSLVE--RTVSETDIIPGDVHNTVKVFMTEP 1824



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 51/218 (23%), Positives = 91/218 (41%), Gaps = 36/218 (16%)

Query: 1466 RNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAAHQKPEASVEQA 1525
            R ++ELQ +L++V+  E E   S  ++  + L   +P           +  K E +V  A
Sbjct: 2949 RKREELQQILSRVKQFEAEPNKS-GLKTFQTLLNTIPGW-------LISEDKREYAVHIA 3000

Query: 1526 F-GELTRVSTEVAQLKEQTLARLLDIEEAVHKALSSMSSLQPEASARGHFQGPPKDHSAH 1584
                L +V  E+  +K Q    L+  E  +  A+ S  + +P             D ++ 
Sbjct: 3001 MENNLEKVKEEITHIKTQAEDMLVSYENIIQTAMMSSKTGKPGNKPTS------LDETSS 3054

Query: 1585 KIS-VTVSSSARPSGSGQEVGGQTAVKNQAKVECHTEAQSQVKIRNHTEARGHTASTAPS 1643
            K+S V VS++        ++  +  V++Q  V  H EA  +  ++ H E +   ++  P 
Sbjct: 3055 KVSNVHVSNNKNSEQKENKIAKEKTVQHQ--VAAHHEATVRSHVKTHQEIKLDDSNIPP- 3111

Query: 1644 TRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRK 1681
                             PS +  P SPTFI+I+S  R+
Sbjct: 3112 -----------------PSLKTRPPSPTFITIESTARR 3132



 Score = 38.5 bits (88), Expect = 0.061
 Identities = 77/394 (19%), Positives = 145/394 (36%), Gaps = 84/394 (21%)

Query: 60   HIHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQCMRWIFENWRLDAIGEHER---PAAKE 116
            H   ELR    E +  +  + +  E+  +GDV+   W+FEN   D+I E  +      KE
Sbjct: 1459 HTMDELR---GEGLEYENIKTVTQEDVQKGDVKQAVWLFENRTFDSIMEAHKGITKMTKE 1515

Query: 117  PVLCGDVQATSRKFEEGSFANSTDQEPTRPQPGG-------------------------- 150
             +   DV+ T+  FE        +    + +  G                          
Sbjct: 1516 EIPPSDVKTTTWLFETTPLHEFNETRVEKIEIIGKSIKETLEDLYSQKVIQAPGIIIEAD 1575

Query: 151  --GDVRAARWLFETKPLDELTGQA--------------KELEATVREPAASGDVQGTRML 194
              GDVR A++    +   E+  +                + + T RE   S + +G   L
Sbjct: 1576 EIGDVRMAKYKLMNQASPEIQKEEIIRADLRNIMVNLLSKRDCTEREILISEEEKGNVNL 1635

Query: 195  FETRPLDRLGSRPSLQEQSPLELRSEIQEL-KGDVKKTVK-LFQTEP-----LCAIQDAE 247
             +T+ L+R             E  +E +E+ KGDV++ +K LF  E      +   +D +
Sbjct: 1636 TKTQLLNR-----------STEFHAEKEEIVKGDVQQAIKNLFSEERSVKKGILIQEDEK 1684

Query: 248  GAIHEVKAACREEIQSNAVRSARWLFET--RPLDAINQDPSQVRVIRGISLEEGARPDVS 305
            G I+        E   + +     +     R +  +    S  ++     ++   R +V 
Sbjct: 1685 GDINMTIYCLLHENDGDTIEREEVIGGDVKRTIHNLLSSTSNNKISERAKIDASERGNVQ 1744

Query: 306  ATRWIFETQPLDAIREILVDE------KDFQPSPDLIPPGPDVQQQQHLFETRALDTLKG 359
                  E   LD ++++  +       K  +   ++I  G DV+  + L + R       
Sbjct: 1745 FFTTCIEAGALDYLKQLHTESNETLTAKKQEGEKEII--GGDVEGTKLLLKKR------- 1795

Query: 360  DEEAGAEAPPKEEVVPGDVRSTLWLFETKPLDAF 393
             +        + +++PGDV +T+ +F T+P   F
Sbjct: 1796 -QSLVERTVSETDIIPGDVHNTVKVFMTEPQSTF 1828



 Score = 37.7 bits (86), Expect = 0.10
 Identities = 43/192 (22%), Positives = 86/192 (44%), Gaps = 55/192 (28%)

Query: 603 MSELAEKQGSEVTDPTA-KAEAQSCTWMFKP--QPVDRPVGSREQHLQVSQVPAGERQTD 659
           +SE++E   S++   ++  A+ Q   ++F+       + + S  ++L+  ++  GE Q+ 
Sbjct: 518 ISEVSEIVSSQMNSGSSVSADVQQARYVFENTNDSSQKDLNSEREYLEWDEILKGEVQSI 577

Query: 660 RHVFETEPLQA--SGRPCGRRPVRYCSRVEIPSGQVSRQKEVFQALEAGKKEEQEPRVIA 717
           R +FE +PL +  +G P                G +SR          G  +++   +IA
Sbjct: 578 RWIFENQPLDSINNGSP--------------DEGDISR----------GIADQE---IIA 610

Query: 718 GSIPAGSVHKFTWLFENCP---MGSLAAESIQGGN---------------LLEEQPMSPS 759
           G    G V   TW+FE  P   +G+ ++++++                  + E +P+  S
Sbjct: 611 G----GDVKYTTWMFETQPIDTLGAYSSDTVENAEKIPELARGDVCTARWMFETRPLD-S 665

Query: 760 GNRMQESQETAA 771
            N+M +SQE +A
Sbjct: 666 MNKMHQSQEESA 677


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 202/863 (23%), Positives = 287/863 (33%), Gaps = 143/863 (16%)

Query: 948  PPADPSPVPAS-EGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAI------GK 1000
            P    SP P S +GA    PT S   V PL P    G       TP P          G 
Sbjct: 850  PATTHSPTPPSPKGA----PTPSA--VTPLSPK---GVTLPPKETPTPSVVNLPFPKEGP 900

Query: 1001 AVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATT----TPPGP-GAPDLLAAM 1055
            A P   +A A +   ++ K+  +    KG+      +GA T    TPP P G P   +  
Sbjct: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 1056 QSLRMATAEAQSLHQQVLNKHKQG-PTPTATSNPIQDG------LRKAGATQSNIRPGGG 1108
             +     A   S          +G PTP A + P   G       + A    +   P   
Sbjct: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 1109 SDPRIPAAPRKVSREEQAL---PRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQ 1165
              P     P+  S    A    P+G P     +  G  T  P  T   P G       P 
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAA-TPLPKGAPTT-PAATLPSPKG---GPATPS 1075

Query: 1166 SRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETT 1225
             +   T  +   P P +GGP   +  G   P   T     PP        P    A  T 
Sbjct: 1076 LKGAPTPPAATPPSP-KGGPATPSPKGAPMPPAAT-----PPSPKGGLATPPHKGAPTTP 1129

Query: 1226 LKTAPLGRHILASGP------QAAGASPHPHNAFVPPP----PTLPAAVTGPDFPAG--- 1272
              T P  +  LA+ P        A   P P      PP    PT PAA   P  P G   
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT--PPSPKGGLA 1187

Query: 1273 --AHRAEDSIQQASEPLKDPLLHSHSSPAGQRTP--------GGSQTKTPKLDPTMPPKK 1322
              + +   +   A+ P     L + S      TP        GG  T +PK  PT P   
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP--- 1244

Query: 1323 KPQLPPKPAHLTQSHPPQRLP-KPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVD 1381
                PP P     + PP+  P  P    PS    +    H+        P PA V     
Sbjct: 1245 -AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK------GAPNPAVVTPPSP 1297

Query: 1382 QGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWG 1441
            +G  P    P G   P      + T P P  +  T     +  PP +      P SP+  
Sbjct: 1298 KGG-PATSPPKGAPTPP-----AATPPSPKGSPGTPPPKGAPTPPAVT-----PPSPKGT 1346

Query: 1442 PGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAV 1501
            P      P   S +G P +P S        +G          +   ++   + +R   A+
Sbjct: 1347 PTLPATTP---SSKGGPTTPSS-------KEGPTPPAATPSHKGGPAMTPPSPKR-GPAI 1395

Query: 1502 PQLGG----------AAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIE 1551
            P   G          +  +APA     E +   + G+LT  +     LK+          
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT------ 1449

Query: 1552 EAVHKALSSMSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQT--AV 1609
             +  K   +  S + + +        PK+  A K   T SS  +   +   +G  T  AV
Sbjct: 1450 -SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508

Query: 1610 KNQAKVECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETS----REYLCPPRV-LPSSR 1664
               +  E      S+         R   A TA    ++  +    +E L PP + +PS +
Sbjct: 1509 IPSSPKEVPATPSSR---------RDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559

Query: 1665 DSPSSPTFISIQSATRKPLETPSFK--GNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKK 1722
             +P+ PT        ++   TPS K   +P     ST       + LL    V   + K+
Sbjct: 1560 KTPAIPT-------PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 1723 DITQCSV-QPEPAPPSASPLPRG 1744
              T  +V  P P    A+P P+G
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKG 1635



 Score = 67.8 bits (164), Expect = 9e-11
 Identities = 180/833 (21%), Positives = 252/833 (30%), Gaps = 94/833 (11%)

Query: 943  SLRWEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCP-----PQA 997
            S +W P    +  P+ +G  +    +     P   P    G      ATP P     P A
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG----GPATPSPKGAPTPPA 1013

Query: 998  IGKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGM-AVLGKSEGATTTPP--------GPGA 1048
            +    P    AA P     +     +    KG  A     +GA TTP         GP  
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 1049 PDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDG-----LRKAGATQSNI 1103
            P L  A      A               K  P P A + P   G       K   T    
Sbjct: 1074 PSLKGAPTP--PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131

Query: 1104 RPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQRE 1163
             P           P+       A P    GG  T         P  T   P G  L+   
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG-GLATPS 1190

Query: 1164 PQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAE 1223
            P+      A +  +P+     P     P        T  A  PP        P    A  
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAP--------TTPAATPPSPKGGLATPSPKGAPT 1242

Query: 1224 TTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQA 1283
            T   T P         P+   A+P P  A  PP  T P+   G   P        ++   
Sbjct: 1243 TPAATPP--------SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 1284 SEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLP 1343
              P   P   + S P G  TP  +   +PK  P  PP K    PP         PP   P
Sbjct: 1295 PSPKGGP---ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT------PPS--P 1343

Query: 1344 KPLPLSPSF--SSEVGQREHQRGERDT---AIPQ----PAKVPTTVDQGHIPLARCPSGH 1394
            K  P  P+   SS+ G       E  T   A P     PA  P +  +G  P    P G 
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG--PAIPSPKGD 1401

Query: 1395 SQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSH 1454
                    LS     P K  AT    + +  P       D T P   P    + P   + 
Sbjct: 1402 PTSPAVIPLS-----PKKAPATPVTREGAATPS----KGDLTPPAVTPVSLKKAPATSAP 1452

Query: 1455 QGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAA 1514
            +G P +P S  +    L   +      E  A   V   +  +   A P   GA       
Sbjct: 1453 KGGPATPSS--KGDPTLPA-VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 1515 HQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALSSMSSLQ-PEASARGH 1573
               P+            ++     L ++T A L   E  +  A++  S  + P       
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 1574 FQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKNQAKVECHTEAQSQVKIRNHTEA 1633
                P    A        S+ + + S +E+    AV + +  E  T           T  
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV-------TPP 1622

Query: 1634 RGHTASTAPSTRRQETSREYLCPPRVLPSS-RDSPSSPTFISIQSATRKPLET---PSFK 1689
                    P+ +   TS      P V PSS +DSP+SP  ++ +     P  +   P+ K
Sbjct: 1623 SPEKGPATPAPKGTPTS------PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676

Query: 1690 GNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASPLP 1742
            G   +       A +    +        +T K   T   + P+P+  + S  P
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 81/314 (25%), Positives = 105/314 (33%), Gaps = 38/314 (12%)

Query: 1158 QLSQREPQSRHRETALSVQ-APRPLQGGPGQSTG---PGREEPGGCTQMAWGPPGKAMAE 1213
            Q S+  P + H  T  S + AP P    P    G   P +E P   T      P      
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---TPSVVNLPFPKEGP 900

Query: 1214 VCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGA 1273
              P   QA   ++ ++   +      P+   ASP P  A  PP  T P+   GP  P+  
Sbjct: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 1274 HRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHL 1333
                        P   P   +  SP G  TP  +   +PK  P  P  K    PP     
Sbjct: 961  WAPTPPAATPPSPKGGP---ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP----A 1013

Query: 1334 TQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPS- 1392
                 P+  P   P     S+              A P P   PTT      P A  PS 
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT------PAATLPSP 1067

Query: 1393 --GHSQPSLQHG---LSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGE 1447
              G + PSL+      + T P P    AT S   +  PP        P SP+ G      
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT-----PPSPKGGLATP-- 1120

Query: 1448 QPMEGSHQGAPESP 1461
                  H+GAP +P
Sbjct: 1121 -----PHKGAPTTP 1129



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 140/621 (22%), Positives = 207/621 (33%), Gaps = 111/621 (17%)

Query: 949  PADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLA-GE 1007
            P  P+  P+S+G     PT       P  P+    H      TP  P+  G A+P   G+
Sbjct: 1347 PTLPATTPSSKGG----PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGD 1401

Query: 1008 AAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQS 1067
              +PA +  + K        K  A     EGA T   G   P  +  + SL+ A A +  
Sbjct: 1402 PTSPAVIPLSPK--------KAPATPVTREGAATPSKGDLTPPAVTPV-SLKKAPATSAP 1452

Query: 1068 LHQQVLNKHKQGPTPTATS--NPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQ 1125
                     K  PT  A +  +P +    K  AT S       S  + PA P  +     
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS-------SPKKAPATPAPMGAP-- 1503

Query: 1126 ALPRGLPGGWVTIQDGIYTAHPVRTFDP--PGGVQLSQREPQSRHRETAL-----SVQAP 1178
             LP  +P     +      A P    DP  P    LS++ P +   + AL     +V +P
Sbjct: 1504 TLPAVIPSSPKEVP-----ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558

Query: 1179 RPLQGGPGQSTGPGR------EEPGGCTQMAW-GPPGKAMAEVCPGGLQAAETTLKTAPL 1231
            +     P     P          P   T   + G P      + P        + K AP 
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPA---VTSPSPKEAPT 1615

Query: 1232 GRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAH-RAEDSIQQASEPL--- 1287
               +    P+   A+P P      PP T  +    P  PA    +   ++ QAS+ L   
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675

Query: 1288 KDP--LLHSHSSPAGQRTP-------GGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHP 1338
            K P  L     +PA + TP        G QTK  K   T PP     + P P+    S  
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTK--KSSATSPP-----ICPDPSAKNGSKG 1728

Query: 1339 PQRLPKPLPLSP---SFSSEVGQREHQRGERDTAIPQPAKVPTTVDQG------------ 1383
            P     P PL P     S     ++     +    P  +K  T +               
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788

Query: 1384 ----------HIPLARCPSGHSQPSLQH-----GLSTTAPRPTKNQATGSNAQSSEPPK- 1427
                       +PLA  P     P  Q      GL   +P      A         PP+ 
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848

Query: 1428 -------LNALNHDPTSPQWG---PGPSGEQPMEGSHQGAPESPDSLQR--NQKELQGLL 1475
                    + L + PT    G   P PS +QP+  +++G+    DS +     +E     
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQ 1908

Query: 1476 NQVQALEKEAASSVDVQALRR 1496
               Q  +  AA+ +D + + +
Sbjct: 1909 ATTQQAQLAAAAEIDEEPVSK 1929



 Score = 38.1 bits (87), Expect = 0.080
 Identities = 127/560 (22%), Positives = 180/560 (32%), Gaps = 98/560 (17%)

Query: 1205 GPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAV 1264
            GP   +     P G     T+   +P    IL S P A    P      V    T P  V
Sbjct: 384  GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVV 443

Query: 1265 TGPDFPAGAHRAEDSIQQASEP--LKDPLLHSH--------SSPAGQRTPGGSQTKTPKL 1314
            T P   A A      +     P     P+ +           +P   + P  +Q  T   
Sbjct: 444  TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEP-STQVATTLR 502

Query: 1315 DPTMPPKKKPQ-LPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQP 1373
             P  PP   P+ L   P+ +    P Q+  + +P S               E     P  
Sbjct: 503  IPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASL--------------EGAPFSPAQ 548

Query: 1374 AKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNH 1433
            A + T  D   +PL +    +S PS Q   S++   P   +AT +     EP  +     
Sbjct: 549  AGLTTKKDPTVLPLVQAAPKNS-PSFQ-STSSSPEIPLSPEATLAKKSLGEPLPIGKPAS 606

Query: 1434 DPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQA 1493
              TSP  G   S       S+ G P+S   L ++      +   V A   E+A    V  
Sbjct: 607  SMTSP-LGVNSSASVIKTDSYAG-PDSAGPLLKSSL----ITPTVAAFPLESADPAGVAP 660

Query: 1494 LRR------LFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTE---VAQLKEQTL 1544
                        A P L G    AP  H   E ++      L   ++E   VA   + T 
Sbjct: 661  TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTL--PLVPTASENCPVAPSPQNTC 718

Query: 1545 ARLLDIEEAVHKALSSMSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVG 1604
            A L  +  A     S  S   P A        PP       IS T  S+  P  S  +  
Sbjct: 719  APLATLVLAPEIPKSVPSPSLPPAGT------PPGTKKVDGISHT--SALAPVASSPK-- 768

Query: 1605 GQTAVKNQAKVECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSR 1664
                       EC TE                  S A +T   + +  YL          
Sbjct: 769  -----------ECPTE-----------------DSGASATASSKGTLTYLA--------- 791

Query: 1665 DSPSSPTFISIQSATRKPLETPSFKGN--PDVSVKSTQLAQDIGQALLHQKGVQDKTGKK 1722
            DSP SP  +S+   T++P   P+ KG+  PD  + +        +A    +      G K
Sbjct: 792  DSP-SPLGVSVSPQTKRP---PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847

Query: 1723 DITQCSVQPEPAPPSASPLP 1742
            D    +  P P  P  +P P
Sbjct: 848  DSPATTHSPTPPSPKGAPTP 867


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 212/933 (22%), Positives = 312/933 (33%), Gaps = 186/933 (19%)

Query: 974  PPLDPSMGMGHLRASGATPCPP-QAIGKAVPLA---GEAAAPAQLQNTEKQEDSHSGQKG 1029
            PP  PS     L     T  PP Q  G   P A   G A  PAQ   +EK      G K 
Sbjct: 331  PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 1030 MAVLGKSEGATTTP---PGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATS 1086
            +A   +  G   TP   PGP  P                    QQV       P P A  
Sbjct: 391  LA---QPPGVGKTPAQQPGPAKPPT------------------QQVGT-----PKPLAQQ 424

Query: 1087 NPIQDGLRKAGATQSNIR-PGGGSDPRIPAAPRKVSREEQAL---PRGLPGGWVTIQDGI 1142
              +Q   +  G T++ ++ PG G  P   A P K S ++      P  LPG     +   
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---PAKPPP 481

Query: 1143 YTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQ--STGPGREEPGGCT 1200
                P +   PP     S + P  +   T    Q P P +  P Q  ST P  ++PG   
Sbjct: 482  QQPGPAK---PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538

Query: 1201 QMAWGP-PGKAMAE-------------------VCPGGLQAAETTL-KT-APLGR--HIL 1236
              A  P P K  A+                   V P   Q     L KT  PL     +L
Sbjct: 539  PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598

Query: 1237 ASGPQAA----------------GASPHPHNAFVPPPPTLPAAVT---GPDFPAGAHRAE 1277
               P+ A                G +P+PH   V     L   +    G D        +
Sbjct: 599  LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658

Query: 1278 DSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSH 1337
              ++ A  P+      S SSP  Q+T       +PK D    PK+     P+P       
Sbjct: 659  PKLKTA--PVTTTSAVSKSSPQPQQT-------SPKKDAA--PKQDLSKAPEP------- 700

Query: 1338 PPQRLPKPLPLSPSFSSEVGQREHQRGERDT-AIPQPAKVPTTV-DQGHIPLARCPSGHS 1395
               + P PL   P+       +  Q  E D+ + P P K P+   +Q   P+A       
Sbjct: 701  ---KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DDKPK 755

Query: 1396 QPSLQH---GLSTTAPRPTKNQATGSNAQSSEPPKLNA-LNHDPTSPQWGPGPSGEQ--P 1449
            QP +      L +++   TK     S  QS    K    L  D   P     P+GE+  P
Sbjct: 756  QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815

Query: 1450 MEGSHQGAPES---------PDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEA 1500
             +      P S         P S  + QK++  +  + +  + +   S    A + + + 
Sbjct: 816  FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKG 874

Query: 1501 VPQLGGAAPQA----PAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHK 1556
             P   G  P A    P   Q P+   +     L   S   A   + T  +    E    K
Sbjct: 875  SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ----ETVTGK 930

Query: 1557 ALSSMSSLQPEASARGHFQGPPKDHS----------AHKISVTVSSSARPSGSGQE---- 1602
                 +S+  +AS      G P  HS          A   S   +S   P  +GQ     
Sbjct: 931  LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990

Query: 1603 -----VGGQTAVKNQAKVECHTEAQSQVKIRNHTE--------ARGHTA----STAPSTR 1645
                 V  +T      K+E   E    VK R  TE        ++  TA    +  P+  
Sbjct: 991  AKSIPVKKETKAPAAEKLEPKAEQAPTVK-RTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 1646 RQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDI 1705
             +    E  CP      +  S   P F +      +      F   P +    T++ + +
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL----TEIQEWL 1105

Query: 1706 GQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASPLPRGWQKSVLELQTGPGSSQHYGAM 1765
                  Q+ +  + G  DI +  + P P+ P ASP+P   + S  +    P        +
Sbjct: 1106 CLNCQTQRAISGQLG--DIRK--MPPAPSGPKASPMPVPTESSSQKTAVPP-------QV 1154

Query: 1766 RTVTEQYEEVDQFGNTVLMSST--TVTEQAEPP 1796
            + V +Q +EV      V++     T++ +  PP
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 106/467 (22%), Positives = 165/467 (35%), Gaps = 73/467 (15%)

Query: 979  SMGMGHLRASGATPCPPQAIGKAVP--LAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKS 1036
            SM  G L    A       + K  P  L  ++ A +Q + T+KQ+     Q      GK 
Sbjct: 151  SMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA-SQEETTKKQKVVQKEQ------GKP 203

Query: 1037 EGATTTP------------PGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHK--QGPTP 1082
            EG    P             GPG   L        +++ + + +  Q     K  QGPT 
Sbjct: 204  EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263

Query: 1083 TATSN----PIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTI 1138
            T  ++    P+Q    +    Q++I  G    P +P      S  +  + +  PG     
Sbjct: 264  TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP------SPSKPPIQQPTPGKPPAQ 317

Query: 1139 QDGIYTAHPVRTFDP--PGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGR--- 1193
            Q G   + P     P  P G+     +P ++   T      P      P Q  GP +   
Sbjct: 318  QPGHEKSQPGPAKPPAQPSGLT----KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373

Query: 1194 EEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHI-----LASGP--QAAGAS 1246
            ++ G     +  P  KA+A+    G   A+      P  + +     LA  P  Q+   +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 1247 PHPHNAFV--PPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTP 1304
            P P    V  P P  +PA   GP         + S QQ   P K P           + P
Sbjct: 434  PGPTKTPVQQPGPGKIPAQQAGP--------GKTSAQQTG-PTKPP----------SQLP 474

Query: 1305 GGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQS-HPPQRLPKPLPLSPSFSSEVGQREHQR 1363
            G ++    +  P  PP ++P     P+    S  PP + P P   SP           Q 
Sbjct: 475  GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534

Query: 1364 GERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRP 1410
            G    +  QP+    +  Q   P+++  SG  +P     +S +A +P
Sbjct: 535  GSAKPSAQQPSPAKPSAQQSTKPVSQTGSG--KPLQPPTVSPSAKQP 579



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 50/172 (29%), Positives = 67/172 (38%), Gaps = 34/172 (19%)

Query: 1296 SSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPP-------------KPAHLTQSHPPQRL 1342
            S P G   P    T+TP+ D    P ++    P             KP+  + S PP + 
Sbjct: 249  SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308

Query: 1343 PKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHG 1402
            P P           G+   Q+   + + P PAK P        PLA+ P G  +P +Q  
Sbjct: 309  PTP-----------GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-GTVKPPVQPP 356

Query: 1403 LSTTAPR----PTKN--QATGSNAQSSEPPKLNALNHDP---TSPQWGPGPS 1445
             +T  P     P K   Q TGS   SSE P   AL   P    +P   PGP+
Sbjct: 357  GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 212/933 (22%), Positives = 312/933 (33%), Gaps = 186/933 (19%)

Query: 974  PPLDPSMGMGHLRASGATPCPP-QAIGKAVPLA---GEAAAPAQLQNTEKQEDSHSGQKG 1029
            PP  PS     L     T  PP Q  G   P A   G A  PAQ   +EK      G K 
Sbjct: 331  PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390

Query: 1030 MAVLGKSEGATTTP---PGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATS 1086
            +A   +  G   TP   PGP  P                    QQV       P P A  
Sbjct: 391  LA---QPPGVGKTPAQQPGPAKPPT------------------QQVGT-----PKPLAQQ 424

Query: 1087 NPIQDGLRKAGATQSNIR-PGGGSDPRIPAAPRKVSREEQAL---PRGLPGGWVTIQDGI 1142
              +Q   +  G T++ ++ PG G  P   A P K S ++      P  LPG     +   
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG---PAKPPP 481

Query: 1143 YTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQ--STGPGREEPGGCT 1200
                P +   PP     S + P  +   T    Q P P +  P Q  ST P  ++PG   
Sbjct: 482  QQPGPAK---PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538

Query: 1201 QMAWGP-PGKAMAE-------------------VCPGGLQAAETTL-KT-APLGR--HIL 1236
              A  P P K  A+                   V P   Q     L KT  PL     +L
Sbjct: 539  PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598

Query: 1237 ASGPQAA----------------GASPHPHNAFVPPPPTLPAAVT---GPDFPAGAHRAE 1277
               P+ A                G +P+PH   V     L   +    G D        +
Sbjct: 599  LHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658

Query: 1278 DSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSH 1337
              ++ A  P+      S SSP  Q+T       +PK D    PK+     P+P       
Sbjct: 659  PKLKTA--PVTTTSAVSKSSPQPQQT-------SPKKDAA--PKQDLSKAPEP------- 700

Query: 1338 PPQRLPKPLPLSPSFSSEVGQREHQRGERDT-AIPQPAKVPTTV-DQGHIPLARCPSGHS 1395
               + P PL   P+       +  Q  E D+ + P P K P+   +Q   P+A       
Sbjct: 701  ---KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DDKPK 755

Query: 1396 QPSLQH---GLSTTAPRPTKNQATGSNAQSSEPPKLNA-LNHDPTSPQWGPGPSGEQ--P 1449
            QP +      L +++   TK     S  QS    K    L  D   P     P+GE+  P
Sbjct: 756  QPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815

Query: 1450 MEGSHQGAPES---------PDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEA 1500
             +      P S         P S  + QK++  +  + +  + +   S    A + + + 
Sbjct: 816  FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA-KPMPKG 874

Query: 1501 VPQLGGAAPQA----PAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHK 1556
             P   G  P A    P   Q P+   +     L   S   A   + T  +    E    K
Sbjct: 875  SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ----ETVTGK 930

Query: 1557 ALSSMSSLQPEASARGHFQGPPKDHS----------AHKISVTVSSSARPSGSGQE---- 1602
                 +S+  +AS      G P  HS          A   S   +S   P  +GQ     
Sbjct: 931  LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990

Query: 1603 -----VGGQTAVKNQAKVECHTEAQSQVKIRNHTE--------ARGHTA----STAPSTR 1645
                 V  +T      K+E   E    VK R  TE        ++  TA    +  P+  
Sbjct: 991  AKSIPVKKETKAPAAEKLEPKAEQAPTVK-RTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 1646 RQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDI 1705
             +    E  CP      +  S   P F +      +      F   P +    T++ + +
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL----TEIQEWL 1105

Query: 1706 GQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASPLPRGWQKSVLELQTGPGSSQHYGAM 1765
                  Q+ +  + G  DI +  + P P+ P ASP+P   + S  +    P        +
Sbjct: 1106 CLNCQTQRAISGQLG--DIRK--MPPAPSGPKASPMPVPTESSSQKTAVPP-------QV 1154

Query: 1766 RTVTEQYEEVDQFGNTVLMSST--TVTEQAEPP 1796
            + V +Q +EV      V++     T++ +  PP
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 106/467 (22%), Positives = 165/467 (35%), Gaps = 73/467 (15%)

Query: 979  SMGMGHLRASGATPCPPQAIGKAVP--LAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKS 1036
            SM  G L    A       + K  P  L  ++ A +Q + T+KQ+     Q      GK 
Sbjct: 151  SMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA-SQEETTKKQKVVQKEQ------GKP 203

Query: 1037 EGATTTP------------PGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHK--QGPTP 1082
            EG    P             GPG   L        +++ + + +  Q     K  QGPT 
Sbjct: 204  EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263

Query: 1083 TATSN----PIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTI 1138
            T  ++    P+Q    +    Q++I  G    P +P      S  +  + +  PG     
Sbjct: 264  TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP------SPSKPPIQQPTPGKPPAQ 317

Query: 1139 QDGIYTAHPVRTFDP--PGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGR--- 1193
            Q G   + P     P  P G+     +P ++   T      P      P Q  GP +   
Sbjct: 318  QPGHEKSQPGPAKPPAQPSGLT----KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373

Query: 1194 EEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHI-----LASGP--QAAGAS 1246
            ++ G     +  P  KA+A+    G   A+      P  + +     LA  P  Q+   +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 1247 PHPHNAFV--PPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTP 1304
            P P    V  P P  +PA   GP         + S QQ   P K P           + P
Sbjct: 434  PGPTKTPVQQPGPGKIPAQQAGP--------GKTSAQQTG-PTKPP----------SQLP 474

Query: 1305 GGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQS-HPPQRLPKPLPLSPSFSSEVGQREHQR 1363
            G ++    +  P  PP ++P     P+    S  PP + P P   SP           Q 
Sbjct: 475  GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534

Query: 1364 GERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRP 1410
            G    +  QP+    +  Q   P+++  SG  +P     +S +A +P
Sbjct: 535  GSAKPSAQQPSPAKPSAQQSTKPVSQTGSG--KPLQPPTVSPSAKQP 579



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 50/172 (29%), Positives = 67/172 (38%), Gaps = 34/172 (19%)

Query: 1296 SSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPP-------------KPAHLTQSHPPQRL 1342
            S P G   P    T+TP+ D    P ++    P             KP+  + S PP + 
Sbjct: 249  SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308

Query: 1343 PKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHG 1402
            P P           G+   Q+   + + P PAK P        PLA+ P G  +P +Q  
Sbjct: 309  PTP-----------GKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP-GTVKPPVQPP 356

Query: 1403 LSTTAPR----PTKN--QATGSNAQSSEPPKLNALNHDP---TSPQWGPGPS 1445
             +T  P     P K   Q TGS   SSE P   AL   P    +P   PGP+
Sbjct: 357  GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 126/561 (22%), Positives = 174/561 (31%), Gaps = 98/561 (17%)

Query: 953  SPVPASEGAQSLHPTESIIHVPPLDPSM--GMGHLRASGATPCPPQAIGKAVPLAGEAAA 1010
            +P   + G  +  P  S    PP+ P+    +G   A G  P   +A G       E+A 
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 1011 PAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTP--------PGP-GAPDLLAAMQSL--- 1058
             A    T +   S  G++       S G  ++P        PGP G   L  + +     
Sbjct: 76   RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 135

Query: 1059 -RMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPA-A 1116
             +   A  +S       +   GPTP   S  +    R AG      RP   + PR P   
Sbjct: 136  GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 195

Query: 1117 PRK---------------VSREEQALPRGL--PGGWVTIQDGIYTAHPVRTFDPPGGVQL 1159
            PRK                +R   +   GL  P            + P R+     G   
Sbjct: 196  PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG--- 252

Query: 1160 SQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGL 1219
            + R P    +     +QA RP Q  P +        P   + +A   P    +   P  L
Sbjct: 253  TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312

Query: 1220 QAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDS 1279
            Q   +   T P         P          ++F+P PP  P A   P  P     A   
Sbjct: 313  QTLPSPPATPPSQATTSLGSPTLQAT-----HSFLPSPPLSPLATPPPQAPPAL--ALPP 365

Query: 1280 IQQASEPLKDPLLHSHSSPAGQRT--------------PGGSQTKTPKLDPTMPPKKKPQ 1325
            +Q    P   P L   ++P+ Q                P     + P   P  PP     
Sbjct: 366  LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425

Query: 1326 LPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHI 1385
             PP  A  + + PP ++P   P SP  S              +A P P   P        
Sbjct: 426  TPPSQAPPSLAAPPLQVPPSPPASPPMS-------------PSATPPPQAPP-------- 464

Query: 1386 PLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTS-PQWGP-G 1443
            PLA  P           L    P P    A  +       P L AL   P S P   P  
Sbjct: 465  PLAAPP-----------LQLAKPPPQAPPALAT-------PPLQALPSPPASFPGQAPFS 506

Query: 1444 PSGEQPMEGSHQGAPESPDSL 1464
            PS   PM       P++P  L
Sbjct: 507  PSASLPMSPLATPPPQAPPVL 527



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 130/535 (24%), Positives = 181/535 (33%), Gaps = 102/535 (19%)

Query: 988  SGATP-CPPQAIGKAVPLAG-EAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPG 1045
            SG TP  P  A+ +    AG E   P    +   +  +   +K ++   +    +TT P 
Sbjct: 156  SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH---STTEPS 212

Query: 1046 PGAPDLLAAMQSL-RMATAEAQSLHQQVLNKHKQGP----TPTATSNPIQDGLRKAGATQ 1100
            P A    +A   L R A+    S    + +  + GP    TP A ++P Q   +   A  
Sbjct: 213  PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-- 270

Query: 1101 SNIRPGGGSDPRIPAAPR--KVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQ 1158
              +RP   + PR  AAP    +S    A P        +    + T  P     PP    
Sbjct: 271  --LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL-PSPPATPPSQAT 327

Query: 1159 LSQREP--QSRHR---ETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAE 1213
             S   P  Q+ H       LS  A  P Q  P  +  P +  P         PP   +A 
Sbjct: 328  TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS----PPLSPLAT 383

Query: 1214 VCPGGLQAAETTLKTAPLGRHIL----------ASGPQAAGASPH---PHNAFVPP---- 1256
              P    A    L  AP                AS P +  A+P    P +   PP    
Sbjct: 384  PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 1257 ------PPTLPAAVTGPDFPAGAHRAEDSIQQASEP------LKDPLLHSHSSPA----G 1300
                  PP  P+A   P  P     A   +Q A  P      L  P L +  SP     G
Sbjct: 444  PSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501

Query: 1301 QR--TPGGSQTKTPKLDPTMPPKKKP-------QLPPKPAHLTQSHPPQRLPKPLPLSPS 1351
            Q   +P  S   +P   P  PP+  P       Q+PP P        P+R P P P    
Sbjct: 502  QAPFSPSASLPMSPLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP---- 555

Query: 1352 FSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGH-SQPSL--QHGLSTTAP 1408
                           DT++  P            P +R PS   S P L      +T+ P
Sbjct: 556  ---------------DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600

Query: 1409 RPTKNQATG--SNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESP 1461
               +   +G    A +S PP        P +   GP P    P+  + +GAP +P
Sbjct: 601  EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP----PL--AFRGAPGAP 649



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 84/332 (25%), Positives = 113/332 (34%), Gaps = 39/332 (11%)

Query: 948  PPADPSPVPASEGAQSLH-PTESIIHVPPLDPSMGMGHLRASGATP---CPPQAIGKAVP 1003
            PP  PS  P S+   SL  P   +   PP  P M         A P    PP  + K  P
Sbjct: 419  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 1004 LAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATA 1063
             A  A A   LQ       S  GQ   +       +    P P AP +LAA   L++  +
Sbjct: 479  QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPS 537

Query: 1064 EAQSLHQQVLNKHKQGPTP---TATSNPIQDGLRKAGATQSNIRPGGG--SDPRIPAAPR 1118
               S     L   ++ PTP   T+ S P        G      R      S P +     
Sbjct: 538  PPAS---PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594

Query: 1119 KVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAP 1178
              +   + L RG   G     +G   A       PP   +L+   P +  R  A     P
Sbjct: 595  SATSTPEEL-RGYDSG----PEGGAAA------SPPPDAELAACHPAAWSRGPA----PP 639

Query: 1179 RPLQGGPG------QSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLG 1232
               +G PG       +TGPG  + G CT   +   G   A   PG L    +   +   G
Sbjct: 640  LAFRGAPGAPLPWPPATGPGSAD-GLCT--IYETEGPESATPAPGALDPGPSPGTSG--G 694

Query: 1233 RHILASGPQAAGASPHPHNAFVPPPPTLPAAV 1264
            +    +G  A+  SP        P   L A+V
Sbjct: 695  KAAAGAGAGASSRSPKQARLGELPLGALQASV 726



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 45/180 (25%), Positives = 66/180 (36%), Gaps = 11/180 (6%)

Query: 1566 PEASARGHFQGPPKD-HSAHKISVTVSSSA---RPSGSGQEVGGQTAVKNQAKVECHTEA 1621
            P A  R   +GP K   SA + S T  S A   RPS  G    G     +++     T  
Sbjct: 185  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG----GLQRPASRSLSSSATPL 240

Query: 1622 QSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRD-SPSSPTFISIQSATR 1680
             S    R+   ARG   + A  ++ +    + L PP+V P  +D +P+     S   AT 
Sbjct: 241  SSPA--RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298

Query: 1681 KPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASP 1740
             P   PS    P +    +  A    QA         +     +    + P   PP  +P
Sbjct: 299  SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 112/462 (24%), Positives = 146/462 (31%), Gaps = 79/462 (17%)

Query: 905  VALTAYSLQPRLTSKASERSSVQLLASCIDKGDLSGLHSLRW--EPPADPSPVPASEGAQ 962
            VAL A S    L    S+  S  L+A         G +  +    PP  P   P   G Q
Sbjct: 8    VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67

Query: 963  SLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQED 1022
                       PP  P    G     G  P  P   GK          P Q   +     
Sbjct: 68   P--------QGPPPPPGKPQGPPPQGGNKPQGPPPPGKP------QGPPPQGDKSRSPRS 113

Query: 1023 SHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTP 1082
                 +G    G ++     PP PG P                Q    Q  NK +  P P
Sbjct: 114  PPGKPQGPPPQGGNQPQGPPPP-PGKP----------------QGPPPQGGNKPQGPPPP 156

Query: 1083 TATSNPIQDGLRKAGATQS------NIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWV 1136
                 P   G  K+ +++S         P GG+ P+ P  P          P+G P    
Sbjct: 157  GKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP-------PGKPQGPPP--- 206

Query: 1137 TIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGG---------PGQ 1187
              Q G     P     P G       + QS  R      Q P P QGG         PG+
Sbjct: 207  --QGGNKPQGPPPPGKPQGPPPQGDNKSQSA-RSPPGKPQGPPP-QGGNQPQGPPPPPGK 262

Query: 1188 STGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASP 1247
              GP  +  GG       PPGK       GG ++  +              G Q  G  P
Sbjct: 263  PQGPPPQ--GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP 320

Query: 1248 HPHNAFVPPP--------PTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPA 1299
             P     PPP        P  P    GP  P G  ++  +     +P + P     ++P 
Sbjct: 321  PPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGGSKSRSARSPPGKP-QGPPQQEGNNPQ 378

Query: 1300 GQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQ-SHPPQ 1340
            G   P G   + P+     PP  +PQ PP+P    + S PPQ
Sbjct: 379  GPPPPAGGNPQQPQ----APPAGQPQGPPRPPQGGRPSRPPQ 416



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 113/439 (25%), Positives = 147/439 (33%), Gaps = 92/439 (20%)

Query: 1051 LLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSD 1110
            LL  +    +A + AQ+L++ V    ++ P+  A  NP                P GG+ 
Sbjct: 2    LLILLSVALLALSSAQNLNEDV--SQEESPSLIA-GNP------------QGAPPQGGNK 46

Query: 1111 PRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRE 1170
            P+ P +P          P+G P      Q G     P     PPG       +PQ    +
Sbjct: 47   PQGPPSP-------PGKPQGPPP-----QGGNQPQGPP---PPPG-------KPQGPPPQ 84

Query: 1171 TALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAP 1230
                 Q P P    PG+  GP  +  G  ++    PPGK       GG Q         P
Sbjct: 85   GGNKPQGPPP----PGKPQGPPPQ--GDKSRSPRSPPGKPQGPPPQGGNQ---------P 129

Query: 1231 LGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDP 1290
             G       PQ     P P     P  P  P    GP  P G +++  S     +P   P
Sbjct: 130  QGPPPPPGKPQG----PPPQGGNKPQGPPPPGKPQGPP-PQGDNKSRSSRSPPGKPQGPP 184

Query: 1291 LLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLP--- 1347
                   P G   P G         P  PP K    PP+  +  Q  PP   P+  P   
Sbjct: 185  -------PQGGNQPQG---------PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228

Query: 1348 --LSPSFSSEVGQRE---HQRGERDTAIPQPAKVP--TTVDQGHIPLARCPSGHSQ-PSL 1399
               S S  S  G+ +    Q G +    P P   P       G+ P    P G  Q P  
Sbjct: 229  DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 288

Query: 1400 QHGLSTTAPR--PTKNQA---TGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSH 1454
            Q G  + + R  P K Q     G N     PP        P  PQ G  P G  P  G  
Sbjct: 289  QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP--PQGGNKPQGPPP-PGKP 345

Query: 1455 QGAPESPDSLQRNQKELQG 1473
            QG P    S  R+ +   G
Sbjct: 346  QGPPPQGGSKSRSARSPPG 364


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 148/651 (22%), Positives = 212/651 (32%), Gaps = 97/651 (14%)

Query: 953  SPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAI------GKAVPLAG 1006
            +P   + G  +  P  S    PP+ P+  +  L A+GA    P A       G  +P + 
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVTPA-ALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 1007 EAAAPAQLQNTEKQED------SHSGQKGMAVLGKSEGATTTP--------PGP-GAPDL 1051
              A P +   T  +        S  G++       S G  ++P        PGP G   L
Sbjct: 75   PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134

Query: 1052 LAAMQSL----RMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGG 1107
              + +      +   A  +S       +   GPTP   S  +    R AG      RP  
Sbjct: 135  RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194

Query: 1108 GSDPRIPA-APRK---------------VSREEQALPRGL--PGGWVTIQDGIYTAHPVR 1149
             + PR P   PRK                +R   +   GL  P            + P R
Sbjct: 195  SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 1150 TFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGK 1209
            +     G   + R P    +     +QA RP Q  P +        P   + +A   P  
Sbjct: 255  SGPSARG---TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311

Query: 1210 AMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGA-SPHPHNAFVPPPPTLPAAVTGPD 1268
              A   P    AA     T P    +    P A  + S  P    +P PP  P +   P 
Sbjct: 312  TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 1269 FPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPG-----GSQTKTPKLDPTM----- 1318
                  +A  S+Q    P++ P  HS +SP+ Q  P        Q  T    PT+     
Sbjct: 372  MTTPPMQAPPSLQTIP-PIQVP--HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428

Query: 1319 -----PPKKKPQL--PPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIP 1371
                 P + +  L  P +PA      PP + P  LP SP   + +           T  P
Sbjct: 429  FLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP 488

Query: 1372 QPAKVPTTVDQGHIPLA-------RCPSGHSQPSLQ-----------HGLSTTAPRPTKN 1413
              A           PL+          S  + PSLQ             L + AP P + 
Sbjct: 489  LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548

Query: 1414 QATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGA---PESPDSLQRNQKE 1470
             +        E P   A    P   Q  P P    P E     A   P++P +L      
Sbjct: 549  ASAPLTTPHLETPPCPA----PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA--SPP 602

Query: 1471 LQGLLN-QVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAAHQKPEA 1520
            LQGL +  +  L      +    AL  L +A P    + P +P A   P+A
Sbjct: 603  LQGLPSPPLSPLATPPPQAPPXLALPPL-QAPPSPPASPPLSPLATPSPQA 652



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 136/593 (22%), Positives = 193/593 (32%), Gaps = 102/593 (17%)

Query: 941  LHSLRWEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGK 1000
            L +L   P   PS  P S     +    S+  +PP+     + H   S +   PP  +  
Sbjct: 354  LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ----VPHSLTSPSLQAPPSPLAL 409

Query: 1001 AVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPG--APDLLAAMQSL 1058
            +   A  +     LQ T         Q   ++   S  A+T P  P   AP  L A   L
Sbjct: 410  SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469

Query: 1059 RMATAEAQSLHQQVLNKHKQGPTPTATSN----PIQDGLRKAGATQSNIRPGGGSDPRIP 1114
            + + + A S     L  H      +  S+    P+   +     TQS++ P     P + 
Sbjct: 470  QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP-----PSLQ 524

Query: 1115 AAPRKVSREE-QALPRGLPGGWVTIQDGIYTAHPVRTFDP-PGGVQLSQREPQSRHRETA 1172
              P  ++    + LP   P    T    + T H      P P  +Q       +   ET 
Sbjct: 525  TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584

Query: 1173 LSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLG 1232
             S+  P P Q  P  ++ P +  P         PP +A   +    LQA  +   + PL 
Sbjct: 585  SSIATPPP-QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643

Query: 1233 RHILASGPQAAGA--------------SPHPHNAFVPP--PPTLPAAV------------ 1264
              +    PQA  A              SP     F PP  PP  P+A             
Sbjct: 644  P-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702

Query: 1265 ---TGPDFPAGAHRAEDSIQ--QASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTM- 1318
                 P  PA    +  +    QA  PL  P L    SP        S T  P++ P + 
Sbjct: 703  PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA 762

Query: 1319 ---------PP---------KKKPQLPPK---PAHLTQSHPPQRLPKPLPLSPSFSSEVG 1357
                     PP         K  PQ PP    P       PP   P   P SPS S  + 
Sbjct: 763  APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822

Query: 1358 QREHQRGERDTAIPQPAKVPTTVDQGHIPLARC-PSGHSQPSLQHGLSTTAPRPTKN--- 1413
                       A P P   P        PL +  PS  + P+LQ       P P  +   
Sbjct: 823  ---------PLATPPPQAPPVLA----APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869

Query: 1414 -QATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQ 1465
             + T + A    PP     +  P+S   GP       + G    A  +P+ L+
Sbjct: 870  PRLTLALAPGPPPPP----SRSPSSTLSGP------DLAGHSSSATSTPEELR 912



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 85/372 (22%), Positives = 128/372 (34%), Gaps = 95/372 (25%)

Query: 1383 GHIPLARCPSGHSQPSLQHGLSTTAPR--PTKNQATGSNAQSSEPPKLNALNHDPTSPQW 1440
            G  PLA    G    ++      +APR  PT++  T S   +S PP        P +   
Sbjct: 54   GRKPLAERAGGIGGATIPE----SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT 109

Query: 1441 GPGP-SGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFE 1499
             PGP S      G+ +  P     L+ + +E    + + +A E    S++   A R    
Sbjct: 110  SPGPVSSPGRASGTTRPGPLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSG 166

Query: 1500 AVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALS 1559
              P        +PA  ++  A+            TEV   +    AR     E   K++S
Sbjct: 167  PTP-----GTPSPAMARRSRAA-----------GTEVGLPRPAPSARPRPPTEGPRKSVS 210

Query: 1560 SM---SSLQPEASAR------GHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVK 1610
            S    S+ +P  +AR      G  Q P         S ++SSSA P  S           
Sbjct: 211  SASEHSTTEPSPAARRRPSAGGGLQRP--------ASRSLSSSATPLSS----------- 251

Query: 1611 NQAKVECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSP 1670
                             R+   ARG   + A  ++ +    + L PP+V P  +D  ++P
Sbjct: 252  ---------------PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD--AAP 294

Query: 1671 TFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCSVQ 1730
                + S+   PL TPS  G     V     A                      T     
Sbjct: 295  ALGPLSSS---PLATPSPSGTKARPVPPPDNA---------------------ATPLPAT 330

Query: 1731 PEPAPPSASPLP 1742
              P+PP A+PLP
Sbjct: 331  LPPSPPLATPLP 342


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 149/653 (22%), Positives = 203/653 (31%), Gaps = 108/653 (16%)

Query: 917  TSKASERSSVQLLASCIDKGDLSG----LHSLRWEPPADPSP-------VPASEGAQSLH 965
            T++AS+  S++        G LSG    L  L+  PP            +   +G   L 
Sbjct: 469  TAEASDTLSIR------SSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLP 522

Query: 966  PTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVP---LAGEAAAPAQLQNTEKQED 1022
            P       P L      G    +GA PCPP      VP     G    P   + T     
Sbjct: 523  PKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSS 582

Query: 1023 SHSGQKGMAVL-GKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPT 1081
             +S Q G   L  K        PG   P     + SLR   A   S    + +     P 
Sbjct: 583  GYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSS-SSDPA 641

Query: 1082 PTATSNP-IQDGLRKAGATQSNIR-PGGGSDPRIPAAPRKVSREEQAL--PRGLPGGWVT 1137
            P+  S P I   L        + + P   S P  P+ PR  +    AL  P  +PG  V+
Sbjct: 642  PSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP--PSKPRSPNPAAPALAAPAVVPGP-VS 698

Query: 1138 IQDGIYTAHPV---------------RTFDPPGGVQLSQREPQSRHRETALSVQAP---- 1178
              D    + P                +   PP     S   P    ++  + V+AP    
Sbjct: 699  TTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASE 758

Query: 1179 ---RPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHI 1235
                PLQ        P   E    +   + PP +A   V         +     P G   
Sbjct: 759  TAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVA--------SPEPAGPSGSPE 810

Query: 1236 LASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSI--------------- 1280
            L S P A+ +S     A    PP  P     P  PA A  A   +               
Sbjct: 811  LVSSPAASSSSA---TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGG 867

Query: 1281 ----QQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKK-----KPQLPPKPA 1331
                +    PL  P L           PGG+   TP L P+ P K        +  P PA
Sbjct: 868  GPPREDVGAPLVTPSLLQMVRLRSVGAPGGA--PTPALGPSAPQKPLRRALSGRASPVPA 925

Query: 1332 HLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTV-------DQGH 1384
              +  H   RL      + S ++  G    Q      A P+P + P +            
Sbjct: 926  PSSGLHAAVRLK-----ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRK 980

Query: 1385 IPLARCPSGHSQPSLQHGL-----STTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQ 1439
            + L R  S  +Q  LQ  L     S +  RP +       A      K +     P SP 
Sbjct: 981  LQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPS 1040

Query: 1440 WGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQ 1492
            +   P  E        G P + D  +R   E  G+L  V   EK      D Q
Sbjct: 1041 Y---PRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQ 1090



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 79/379 (20%), Positives = 122/379 (32%), Gaps = 42/379 (11%)

Query: 1176 QAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHI 1235
            + P P    P +   P    P      A  P   +  +  P      +TTL   PL    
Sbjct: 665  KVPAPFSPPPSKPRSPNPAAPA-LAAPAVVPGPVSTTDASPQSPPTPQTTL--TPLQESP 721

Query: 1236 LASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSH 1295
            + S  Q+   SP P  ++ PPPP         + P+ +  AE+ +Q  + P   P     
Sbjct: 722  VISKDQSPPPSPPP--SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEE 779

Query: 1296 SSPAGQRTPGGSQTKTPKLDP-TMPPKKKPQLPPKPAHLTQS------------HPPQRL 1342
               +    P   +       P    P   P+L   PA  + S             PP   
Sbjct: 780  QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAP 839

Query: 1343 PKPLPLS--PSFSSEVGQREHQRGERDTAIPQ-----PAKVPTTVDQGHIPLARCPSGHS 1395
            P P P S  P   +++ Q+E     +    P+     P   P+ +    +     P G  
Sbjct: 840  PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAP 899

Query: 1396 QPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLN---ALNHDPTSPQWGPGPSGEQPMEG 1452
             P+    L  +AP+    +A    A     P      A+     S     G S  QP  G
Sbjct: 900  TPA----LGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQP-NG 954

Query: 1453 SHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLF--------EAVPQL 1504
              +  P  P S       +    ++   LE+  +        R L         +  PQ 
Sbjct: 955  PPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQA 1014

Query: 1505 GGAAPQA-PAAHQKPEASV 1522
               +P+A P   +KP   V
Sbjct: 1015 PKKSPKAPPPVARKPSVGV 1033


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 107/562 (19%)

Query: 1034 GKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLH-QQVLNKHKQGP-TPTATSNPIQD 1091
            G +  AT  PP  G+P    A    +  TA     H QQ    H Q P +P    +P   
Sbjct: 211  GPTPSATAVPP-QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--- 266

Query: 1092 GLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHP--VR 1149
                  +    ++P  GS  + P+AP   S  +  L    P G  ++Q G    HP   +
Sbjct: 267  ------SPHPPLQPLTGSAGQ-PSAP---SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316

Query: 1150 TFDPPGGVQLSQR----EPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWG 1205
             F  P      Q      P + +  T+L + A +       QS  P RE+P         
Sbjct: 317  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL----QSQQPPREQP-------LP 365

Query: 1206 PPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL-PAAV 1264
            P   AM  + P       T +   P  +      P  +G SP   NA +PPPP L P + 
Sbjct: 366  PAPLAMPHIKP----PPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKP 1324
                 P  AH     +   S+PL        SSPA  + PG +Q++              
Sbjct: 421  LSTHHPPSAHPPPLQLMPQSQPLP-------SSPA--QPPGLTQSQ-------------- 457

Query: 1325 QLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGH 1384
             LPP PA    SHPP  L +  P  P       Q     G      P P   PT      
Sbjct: 458  NLPPPPA----SHPPTGLHQVAPQPP-----FAQHPFVPGG-----PPPITPPT------ 497

Query: 1385 IPLARCPSGHSQPSLQHGLSTTAPRPTKNQAT--GSNAQSSEPP------KLNALNHDPT 1436
                 CPS  + P+   G  T+A  P    A   GS A  S  P      K  AL+ D  
Sbjct: 498  -----CPSTSTPPA---GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD-DAE 548

Query: 1437 SPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRR 1496
             P+  P P      E +    P       R  K L    N     +         +  ++
Sbjct: 549  EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKK 608

Query: 1497 LFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHK 1556
              EA+ +    A Q     ++ E   E+          E  + +E+   R      + H+
Sbjct: 609  REEAIEKAKREAEQKAREEREREKEKEK--------EREREREREREAERAAKASSSAHE 660

Query: 1557 ALSSMSSLQPEASARGHFQGPP 1578
               S   L      R  F+ PP
Sbjct: 661  GRLSDPQLSGPGHMRPSFEPPP 682



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 100/427 (23%), Positives = 137/427 (32%), Gaps = 102/427 (23%)

Query: 947  EPPADPSPVPAS--EGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPL 1004
            +P A  +PVP +  + A +LHP       PP  PS            P PP       PL
Sbjct: 233  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------------PHPP-----LQPL 275

Query: 1005 AGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLL---AAMQSLRMA 1061
             G A  P+    +  Q   H GQ          G     PGP  P  L   A+     + 
Sbjct: 276  TGSAGQPS--APSHAQPPLH-GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 332

Query: 1062 TAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVS 1121
            T+ A +     L          +   P +  L  A     +I+P     P     P+  +
Sbjct: 333  TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPA 387

Query: 1122 REEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQ----LSQREPQSRHRETALSVQA 1177
             +    P  L G      +            PP  ++    LS   P S H      +  
Sbjct: 388  PQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439

Query: 1178 PRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILA 1237
             +PL   P Q        P G TQ    PP  A                   P G H +A
Sbjct: 440  SQPLPSSPAQ--------PPGLTQSQNLPPPPA----------------SHPPTGLHQVA 475

Query: 1238 SGPQAAGASPHPHNAFVPP---PPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHS 1294
              P  A    HP     PP   PPT P+  T P  P            A  P       S
Sbjct: 476  PQPPFA---QHPFVPGGPPPITPPTCPSTSTPPAGPG---------TSAQPPC------S 517

Query: 1295 HSSPAGQRTPGGSQTKTPKL---DPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPL--- 1348
             ++ +G    GGS    P +   +  +   ++P+ PP         PP R P P P    
Sbjct: 518  GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---------PPPRSPSPEPTVVD 568

Query: 1349 SPSFSSE 1355
            +PS +S+
Sbjct: 569  TPSHASQ 575



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 48/209 (22%), Positives = 67/209 (32%), Gaps = 13/209 (6%)

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQR-TPGGSQTKTPKLDPTMPPKKK 1323
            T P  P+      DS   A + +      +  +P G    P  +   TP+L    P    
Sbjct: 157  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA 216

Query: 1324 PQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVD-Q 1382
              +PP+ +      P Q      P+  +   +      QR       P P+  P      
Sbjct: 217  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT 276

Query: 1383 GHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGP 1442
            G       PS H+QP L HG     P   +    G   Q   PP+   L   P     G 
Sbjct: 277  GSAGQPSAPS-HAQPPL-HGQGPPGPHSLQ---AGPLLQHPGPPQPFGL---PPQASQGQ 328

Query: 1443 GPSGEQPMEG---SHQGAPESPDSLQRNQ 1468
             P G  P      +    P S  +LQ  Q
Sbjct: 329  APLGTSPAAAYPHTSLQLPASQSALQSQQ 357


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 107/562 (19%)

Query: 1034 GKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLH-QQVLNKHKQGP-TPTATSNPIQD 1091
            G +  AT  PP  G+P    A    +  TA     H QQ    H Q P +P    +P   
Sbjct: 765  GPTPSATAVPP-QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--- 820

Query: 1092 GLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHP--VR 1149
                  +    ++P  GS  + P+AP   S  +  L    P G  ++Q G    HP   +
Sbjct: 821  ------SPHPPLQPLTGSAGQ-PSAP---SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 1150 TFDPPGGVQLSQR----EPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWG 1205
             F  P      Q      P + +  T+L + A +       QS  P RE+P         
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL----QSQQPPREQP-------LP 919

Query: 1206 PPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL-PAAV 1264
            P   AM  + P       T +   P  +      P  +G SP   NA +PPPP L P + 
Sbjct: 920  PAPLAMPHIKP----PPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKP 1324
                 P  AH     +   S+PL        SSPA  + PG +Q++              
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLP-------SSPA--QPPGLTQSQ-------------- 1011

Query: 1325 QLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGH 1384
             LPP PA    SHPP  L +  P  P       Q     G      P P   PT      
Sbjct: 1012 NLPPPPA----SHPPTGLHQVAPQPP-----FAQHPFVPGG-----PPPITPPT------ 1051

Query: 1385 IPLARCPSGHSQPSLQHGLSTTAPRPTKNQAT--GSNAQSSEPP------KLNALNHDPT 1436
                 CPS  + P+   G  T+A  P    A   GS A  S  P      K  AL+ D  
Sbjct: 1052 -----CPSTSTPPA---GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD-DAE 1102

Query: 1437 SPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRR 1496
             P+  P P      E +    P       R  K L    N     +         +  ++
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKK 1162

Query: 1497 LFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHK 1556
              EA+ +    A Q     ++ E   E+          E  + +E+   R      + H+
Sbjct: 1163 REEAIEKAKREAEQKAREEREREKEKEK--------EREREREREREAERAAKASSSAHE 1214

Query: 1557 ALSSMSSLQPEASARGHFQGPP 1578
               S   L      R  F+ PP
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPP 1236



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 100/427 (23%), Positives = 137/427 (32%), Gaps = 102/427 (23%)

Query: 947  EPPADPSPVPAS--EGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPL 1004
            +P A  +PVP +  + A +LHP       PP  PS            P PP       PL
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------------PHPP-----LQPL 829

Query: 1005 AGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLL---AAMQSLRMA 1061
             G A  P+    +  Q   H GQ          G     PGP  P  L   A+     + 
Sbjct: 830  TGSAGQPS--APSHAQPPLH-GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886

Query: 1062 TAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVS 1121
            T+ A +     L          +   P +  L  A     +I+P     P     P+  +
Sbjct: 887  TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPA 941

Query: 1122 REEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQ----LSQREPQSRHRETALSVQA 1177
             +    P  L G      +            PP  ++    LS   P S H      +  
Sbjct: 942  PQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993

Query: 1178 PRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILA 1237
             +PL   P Q        P G TQ    PP  A                   P G H +A
Sbjct: 994  SQPLPSSPAQ--------PPGLTQSQNLPPPPA----------------SHPPTGLHQVA 1029

Query: 1238 SGPQAAGASPHPHNAFVPP---PPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHS 1294
              P  A    HP     PP   PPT P+  T P  P            A  P       S
Sbjct: 1030 PQPPFA---QHPFVPGGPPPITPPTCPSTSTPPAGPG---------TSAQPPC------S 1071

Query: 1295 HSSPAGQRTPGGSQTKTPKL---DPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPL--- 1348
             ++ +G    GGS    P +   +  +   ++P+ PP         PP R P P P    
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---------PPPRSPSPEPTVVD 1122

Query: 1349 SPSFSSE 1355
            +PS +S+
Sbjct: 1123 TPSHASQ 1129



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 48/209 (22%), Positives = 67/209 (32%), Gaps = 13/209 (6%)

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQR-TPGGSQTKTPKLDPTMPPKKK 1323
            T P  P+      DS   A + +      +  +P G    P  +   TP+L    P    
Sbjct: 711  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA 770

Query: 1324 PQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVD-Q 1382
              +PP+ +      P Q      P+  +   +      QR       P P+  P      
Sbjct: 771  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT 830

Query: 1383 GHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGP 1442
            G       PS H+QP L HG     P   +    G   Q   PP+   L   P     G 
Sbjct: 831  GSAGQPSAPS-HAQPPL-HGQGPPGPHSLQ---AGPLLQHPGPPQPFGL---PPQASQGQ 882

Query: 1443 GPSGEQPMEG---SHQGAPESPDSLQRNQ 1468
             P G  P      +    P S  +LQ  Q
Sbjct: 883  APLGTSPAAAYPHTSLQLPASQSALQSQQ 911


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 137/562 (24%), Positives = 191/562 (33%), Gaps = 107/562 (19%)

Query: 1034 GKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLH-QQVLNKHKQGP-TPTATSNPIQD 1091
            G +  AT  PP  G+P    A    +  TA     H QQ    H Q P +P    +P   
Sbjct: 765  GPTPSATAVPP-QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP--- 820

Query: 1092 GLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHP--VR 1149
                  +    ++P  GS  + P+AP   S  +  L    P G  ++Q G    HP   +
Sbjct: 821  ------SPHPPLQPLTGSAGQ-PSAP---SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 1150 TFDPPGGVQLSQR----EPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWG 1205
             F  P      Q      P + +  T+L + A +       QS  P RE+P         
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL----QSQQPPREQP-------LP 919

Query: 1206 PPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTL-PAAV 1264
            P   AM  + P       T +   P  +      P  +G SP   NA +PPPP L P + 
Sbjct: 920  PAPLAMPHIKP----PPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKP 1324
                 P  AH     +   S+PL        SSPA  + PG +Q++              
Sbjct: 975  LSTHHPPSAHPPPLQLMPQSQPLP-------SSPA--QPPGLTQSQ-------------- 1011

Query: 1325 QLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGH 1384
             LPP PA    SHPP  L +  P  P       Q     G      P P   PT      
Sbjct: 1012 NLPPPPA----SHPPTGLHQVAPQPP-----FAQHPFVPGG-----PPPITPPT------ 1051

Query: 1385 IPLARCPSGHSQPSLQHGLSTTAPRPTKNQAT--GSNAQSSEPP------KLNALNHDPT 1436
                 CPS  + P+   G  T+A  P    A   GS A  S  P      K  AL+ D  
Sbjct: 1052 -----CPSTSTPPA---GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALD-DAE 1102

Query: 1437 SPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRR 1496
             P+  P P      E +    P       R  K L    N     +         +  ++
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKK 1162

Query: 1497 LFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHK 1556
              EA+ +    A Q     ++ E   E+          E  + +E+   R      + H+
Sbjct: 1163 REEAIEKAKREAEQKAREEREREKEKEK--------EREREREREREAERAAKASSSAHE 1214

Query: 1557 ALSSMSSLQPEASARGHFQGPP 1578
               S   L      R  F+ PP
Sbjct: 1215 GRLSDPQLSGPGHMRPSFEPPP 1236



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 100/427 (23%), Positives = 137/427 (32%), Gaps = 102/427 (23%)

Query: 947  EPPADPSPVPAS--EGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPL 1004
            +P A  +PVP +  + A +LHP       PP  PS            P PP       PL
Sbjct: 787  QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------------PHPP-----LQPL 829

Query: 1005 AGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLL---AAMQSLRMA 1061
             G A  P+    +  Q   H GQ          G     PGP  P  L   A+     + 
Sbjct: 830  TGSAGQPS--APSHAQPPLH-GQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886

Query: 1062 TAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVS 1121
            T+ A +     L          +   P +  L  A     +I+P     P     P+  +
Sbjct: 887  TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKP-----PPTTPIPQLPA 941

Query: 1122 REEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQ----LSQREPQSRHRETALSVQA 1177
             +    P  L G      +            PP  ++    LS   P S H      +  
Sbjct: 942  PQAHKHPPHLSGPSPFSMNA--------NLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993

Query: 1178 PRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILA 1237
             +PL   P Q        P G TQ    PP  A                   P G H +A
Sbjct: 994  SQPLPSSPAQ--------PPGLTQSQNLPPPPA----------------SHPPTGLHQVA 1029

Query: 1238 SGPQAAGASPHPHNAFVPP---PPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHS 1294
              P  A    HP     PP   PPT P+  T P  P            A  P       S
Sbjct: 1030 PQPPFA---QHPFVPGGPPPITPPTCPSTSTPPAGPG---------TSAQPPC------S 1071

Query: 1295 HSSPAGQRTPGGSQTKTPKL---DPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPL--- 1348
             ++ +G    GGS    P +   +  +   ++P+ PP         PP R P P P    
Sbjct: 1072 GAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP---------PPPRSPSPEPTVVD 1122

Query: 1349 SPSFSSE 1355
            +PS +S+
Sbjct: 1123 TPSHASQ 1129



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 48/209 (22%), Positives = 67/209 (32%), Gaps = 13/209 (6%)

Query: 1265 TGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQR-TPGGSQTKTPKLDPTMPPKKK 1323
            T P  P+      DS   A + +      +  +P G    P  +   TP+L    P    
Sbjct: 711  TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA 770

Query: 1324 PQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVD-Q 1382
              +PP+ +      P Q      P+  +   +      QR       P P+  P      
Sbjct: 771  TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT 830

Query: 1383 GHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGP 1442
            G       PS H+QP L HG     P   +    G   Q   PP+   L   P     G 
Sbjct: 831  GSAGQPSAPS-HAQPPL-HGQGPPGPHSLQ---AGPLLQHPGPPQPFGL---PPQASQGQ 882

Query: 1443 GPSGEQPMEG---SHQGAPESPDSLQRNQ 1468
             P G  P      +    P S  +LQ  Q
Sbjct: 883  APLGTSPAAAYPHTSLQLPASQSALQSQQ 911


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 120/465 (25%), Positives = 156/465 (33%), Gaps = 63/465 (13%)

Query: 947  EPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAG 1006
            EPP      P   G Q   P      + P  P+     LR     P P  + G   P+  
Sbjct: 88   EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLR-----PPPEGSAGSCAPVPA 142

Query: 1007 EAAAPAQLQNTEKQEDSHSGQKGMAV-LGKSEGATTTP---PGPGAPDLLAAMQSLRMAT 1062
             AA  A  +         +G   +A   G   G    P   PGPG P    A Q+L  + 
Sbjct: 143  AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202

Query: 1063 AEAQSLH--QQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPG---GGSDPRIPAAP 1117
            A   S H     ++    GP            L K  A  + I+     G + P  PAAP
Sbjct: 203  ALLNSHHAAAPAVSLVNNGPAALLP-------LPKPAAPGTVIQTPPFVGAAAPPAPAAP 255

Query: 1118 RKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQA 1177
               +    A P   P              P     PP           +++  +A +  A
Sbjct: 256  SPPAAPAPAAPAAAPPP-PPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314

Query: 1178 PRPLQGGP-GQSTGPGREEPGGCTQM-AWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHI 1235
            P P  GGP G S  PG   PG      A G   ++   V      AA+T   + P     
Sbjct: 315  PAPAAGGPAGVSGQPG---PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAA 371

Query: 1236 -LASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHS 1294
             +  GP   GA P P  A VPPP   P   TG   P GA  A              +  S
Sbjct: 372  SMVIGPTMQGALPSP--AAVPPP--APGTPTG--LPKGAAGA--------------VTQS 411

Query: 1295 HSSPAGQRTPGGSQTKTPK-LDPTMP-PKKKP------QLPPKPAHLTQSHPPQRLPKPL 1346
             S      T G   T TP  L P +P P + P      QLPP    L +S   Q L    
Sbjct: 412  LSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV-LVRSENGQLL---- 466

Query: 1347 PLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCP 1391
             + P  +    Q +     + T  P+PA  PT+     I   + P
Sbjct: 467  -MIPQQALAQMQAQAHAQPQTTMAPRPA-TPTSAPPVQISTVQAP 509



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 161/738 (21%), Positives = 234/738 (31%), Gaps = 152/738 (20%)

Query: 1079 GPTPTATSNPIQDGLRKAGATQSNIRPGGGSD----------PRIPAAPRKVSREEQALP 1128
            GP   A   P   G           RPGGG            P +PA P   + + +  P
Sbjct: 74   GPAAPAEGAP---GAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP 130

Query: 1129 RGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQA-PRPLQG-GPG 1186
             G  G    +      A          G + +   P       AL+ +A P P  G GPG
Sbjct: 131  EGSAGSCAPVPAAAAVA---------AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPG 181

Query: 1187 QSTGPGREEPGGCTQMAWGP-----------PGKAMAEVCPGGL------QAAETTLKTA 1229
               GPG+    G  Q   G            P  ++    P  L       A  T ++T 
Sbjct: 182  PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTP 241

Query: 1230 PLGRHIL-----ASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSI---- 1280
            P           A  P AA A   P  A  PPPP        P  PAG   A  ++    
Sbjct: 242  PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301

Query: 1281 ------QQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLT 1334
                     + P   P     +  +GQ  PG +            PK+  Q  P  A   
Sbjct: 302  AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361

Query: 1335 QSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGH 1394
             +  P      + + P+                 A+P PA VP        P    P+G 
Sbjct: 362  AASGPASTAASMVIGPTMQG--------------ALPSPAAVPP-------PAPGTPTGL 400

Query: 1395 SQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSH 1454
             + +      + +  PT   AT S  +++  P + A    P  PQ               
Sbjct: 401  PKGAAGAVTQSLSRTPT---ATTSGIRATLTPTVLA----PRLPQ--------------- 438

Query: 1455 QGAPESPDSLQRNQKELQGLL-----NQVQALEKEAASSVDVQALRRLFEAVPQLGGA-A 1508
               P++P ++Q  Q     +L      Q+  + ++A + +  QA      A PQ   A  
Sbjct: 439  --PPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQA-----HAQPQTTMAPR 491

Query: 1509 PQAPAAHQKPEASVEQAFGE--LTRVSTEVAQLKEQTLARLLDIEEAVHKALSSMSSLQP 1566
            P  P +    + S  QA G   + R  T    +K+ + A+      A    L     +QP
Sbjct: 492  PATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSA---TLQRSPGVQP 548

Query: 1567 EASARGHFQ----GPPKDHSAHKISVTVSSSARPSGSGQEVGG---------QTAVKNQA 1613
            +    G  Q    G            TV  +   S +  E             T +K  +
Sbjct: 549  QLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLAS 608

Query: 1614 KVECHTEAQSQVK--IRNHTEARGHTASTAPSTRRQETS--REYLCP--PRVLPSSRD-S 1666
              +  TE  + VK  ++N  + +           R+  S  + YL P   R LP+ R  +
Sbjct: 609  SGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLT 668

Query: 1667 PSSPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQ 1726
            P S  FI  QS  + P         P  S  +T L      A++    VQ   GK   T 
Sbjct: 669  PDSAAFIQ-QSQQQPP---------PPTSQATTALT-----AVVLSSSVQRTAGKTAATV 713

Query: 1727 CSVQPEPAPPSASPLPRG 1744
             S    P      P   G
Sbjct: 714  TSALQPPVLSLTQPTQVG 731



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 88/377 (23%), Positives = 111/377 (29%), Gaps = 63/377 (16%)

Query: 1177 APRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHIL 1236
            APR  +     +   G     G    A G    A AE  PG         +  P G    
Sbjct: 44   APRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG---- 99

Query: 1237 ASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHS 1296
              GPQ  G  P P    VP  P  PAA   P  P G+  +   +  A+     P      
Sbjct: 100  -GGPQRPGP-PSPRRPLVPAGPAPPAAKLRPP-PEGSAGSCAPVPAAAAVAAGP----EP 152

Query: 1297 SPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKP---------------AHLTQSH---- 1337
            +PAG   P G      +  P   P   P   P P               A L  SH    
Sbjct: 153  APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAA 212

Query: 1338 ---------PPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLA 1388
                     P   LP P P +P    +             A P P   P        P A
Sbjct: 213  PAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA----APAA 268

Query: 1389 RCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHD-------PTSPQWG 1441
              P     P+       T  RP  + A    A  + PP   A N         P     G
Sbjct: 269  APPPPPPAPA-------TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321

Query: 1442 PGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAV 1501
            P     QP  G+   AP      +  ++ +Q      Q L     +S     +       
Sbjct: 322  PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV-----IG 376

Query: 1502 PQLGGAAPQAPAAHQKP 1518
            P + GA P +PAA   P
Sbjct: 377  PTMQGALP-SPAAVPPP 392



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 75/296 (25%), Positives = 97/296 (32%), Gaps = 76/296 (25%)

Query: 1242 AAGASPHPHNAFVPPPPTLPAAVTGP-------DFPAGAHRAEDSIQQASEPLKDPLLHS 1294
            AA A+ H H A  P  P + AA  G          PAGA  A  +      P   P    
Sbjct: 34   AASAAHHHHLA--PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP---- 87

Query: 1295 HSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSS 1354
               PAG+  PGG   + P      P  ++P +P  PA      PP    +P P       
Sbjct: 88   EPPPAGRARPGGGGPQRPG----PPSPRRPLVPAGPA------PPAAKLRPPP------- 130

Query: 1355 EVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTA-PRPTKN 1413
                     G   +  P PA     V  G  P    P+G ++P+    L+  A P P   
Sbjct: 131  --------EGSAGSCAPVPAAA--AVAAGPEP---APAGPAKPAGPAALAARAGPGPGPG 177

Query: 1414 QATGSNAQSSEPPKLNALNHDPTSPQWGPGPS----GEQPMEGSHQGAPESPDSLQRNQK 1469
               G      +P               GPG +    G   +  SH  A  +   +     
Sbjct: 178  PGPGPGPGPGKPA--------------GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA 223

Query: 1470 ELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAAHQKPEASVEQA 1525
             L         L K AA    +Q         P +G AAP APAA   P A    A
Sbjct: 224  ALL-------PLPKPAAPGTVIQT-------PPFVGAAAPPAPAAPSPPAAPAPAA 265


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
            sapiens]
          Length = 309

 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 88/340 (25%), Positives = 112/340 (32%), Gaps = 55/340 (16%)

Query: 1051 LLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSD 1110
            LL  +    +A + AQSL++ V     Q  +P+  S   +             RP GG+ 
Sbjct: 2    LLILLSVALLALSSAQSLNEDV----SQEESPSVISGKPEGR-----------RPQGGNQ 46

Query: 1111 P-RIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHR 1169
            P R P  P K        P G P        G           PP G   SQ  P    +
Sbjct: 47   PQRTPPPPGK--------PEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK 98

Query: 1170 ETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCP--GGLQAAETTLK 1227
                  Q     QG P +   P    P G  Q    PP     E  P  GG Q+     +
Sbjct: 99   PEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 158

Query: 1228 TAPLGRHILASGPQAAGASPHPHNAFVPPP---------PTLPAAVTGPDFPAGAHRAED 1278
                       G Q+ G  PHP     PPP         P  P    GP  P G +    
Sbjct: 159  PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP-PQGGN---- 213

Query: 1279 SIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTM----PPKK--KPQLPPKPAH 1332
               Q+  P   P       P G  + GG++ + P   P      PP++  KPQ PP P  
Sbjct: 214  ---QSQGPPPRP-----GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR 265

Query: 1333 LTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQ 1372
                 PP   P+  PL P      G     +G R    PQ
Sbjct: 266  PQGPPPPGGNPQQ-PLPPPAGKPQGPPPPPQGGRPHRPPQ 304



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 84/319 (26%), Positives = 101/319 (31%), Gaps = 73/319 (22%)

Query: 1147 PVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGP 1206
            P RT  PPG       +P+ R  +     Q P P    PG+  GP    P G  Q    P
Sbjct: 47   PQRTPPPPG-------KPEGRPPQGGNQSQGPPPR---PGKPEGP---PPQGGNQSQGPP 93

Query: 1207 PGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPP--------- 1257
            P     E  P             P G      G Q+ G  P P     PPP         
Sbjct: 94   PRPGKPEGQP-------------PQG------GNQSQGPPPRPGKPEGPPPQGGNQSQGP 134

Query: 1258 PTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPT 1317
            P  P    GP  P G +       Q+  P   P       P G    GG+Q++ P     
Sbjct: 135  PPRPGKPEGPP-PQGGN-------QSQGPPPRP-----GKPEGPPPQGGNQSQGPP---- 177

Query: 1318 MPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVP 1377
             P   KP+ PP         PP R  KP    P   ++      + G+ +    Q    P
Sbjct: 178  -PHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKP 236

Query: 1378 TTVDQGHIPLARCPSGHSQPSLQHGLSTTAP----RPTKNQATGSNAQSSEPPKLNALNH 1433
                QG  P    P G   P  Q G     P    RP      G N Q   PP       
Sbjct: 237  ----QGPPPHPGKPQG---PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG 289

Query: 1434 DPTSPQWG---PGPSGEQP 1449
             P  PQ G     P G+ P
Sbjct: 290  PPPPPQGGRPHRPPQGQPP 308



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 57/229 (24%), Positives = 78/229 (34%), Gaps = 32/229 (13%)

Query: 1255 PPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSS---------PAGQRTPG 1305
            PPPP  P        P G ++++    +  +P   P    + S         P GQ   G
Sbjct: 51   PPPPGKPEGRP----PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQG 106

Query: 1306 GSQTKTPKLDPTMPPKKKPQ-------LPPKPAHLTQSHPPQ-----RLPKPLPLSPSFS 1353
            G+Q++ P   P  P    PQ        PP+P    +  PPQ     + P P P  P   
Sbjct: 107  GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK-PEGPPPQGGNQSQGPPPRPGKPEGP 165

Query: 1354 SEVGQREHQRGERDTAIPQ-PAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTK 1412
               G  + Q        P+ P        QG  P    P G   P  Q G  +  P P  
Sbjct: 166  PPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG---PPPQGGNQSQGPPPRP 222

Query: 1413 NQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESP 1461
             +  G  +Q    P+       P  PQ  P   G +P      G P+ P
Sbjct: 223  GKPEGPPSQGGNKPQ--GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGP 269


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 133/596 (22%), Positives = 185/596 (31%), Gaps = 129/596 (21%)

Query: 953  SPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAI------GKAVPLAG 1006
            +P   + G  +  P  S    PP+ P+  +  L A+GA    P A       G  +P + 
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVTPA-ALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 1007 EAAAPAQLQNTEKQED------SHSGQKGMAVLGKSEGATTTP--------PGP-GAPDL 1051
              A P +   T  +        S  G++       S G  ++P        PGP G   L
Sbjct: 75   PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134

Query: 1052 LAAMQSL----RMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGG 1107
              + +      +   A  +S       +   GPTP   S  +    R AG      RP  
Sbjct: 135  RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194

Query: 1108 GSDPRIPA-APRK---------------VSREEQALPRGL--PGGWVTIQDGIYTAHPVR 1149
             + PR P   PRK                +R   +   GL  P            + P R
Sbjct: 195  SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 1150 TFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGK 1209
            +     G   + R P    +     +QA RP Q  P +        P   + +A   P  
Sbjct: 255  SGPSARG---TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311

Query: 1210 AMAEVCPGGLQAAETTLK----------------TAPLGRHILASGP-----QAAGASPH 1248
            A+    P  L A   +                  +AP     L S P     QA  +   
Sbjct: 312  ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371

Query: 1249 PH----NAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRT- 1303
            P     ++F+P PP  P A   P  P     A   +Q    P   P L   ++P+ Q   
Sbjct: 372  PTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAPPSPPASPPLSPLATPSPQAPN 429

Query: 1304 -------------PGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSP 1350
                         P     + P   P  PP      PP  A  + + PP ++P   P SP
Sbjct: 430  ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 489

Query: 1351 SFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRP 1410
              S              +A P P   P        PLA  P           L    P P
Sbjct: 490  PMS-------------PSATPPPQAPP--------PLAAPP-----------LQLAKPPP 517

Query: 1411 TKNQATGSNAQSSEPPKLNALNHDPTS-PQWGP-GPSGEQPMEGSHQGAPESPDSL 1464
                A  +       P L AL   P S P   P  PS   PM       P++P  L
Sbjct: 518  QAPPALAT-------PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 128/553 (23%), Positives = 173/553 (31%), Gaps = 95/553 (17%)

Query: 948  PPADPSPVPASEGAQ------SLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKA 1001
            P     P P +EG +      S H T          PS G G  R     P        A
Sbjct: 192  PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-----PASRSLSSSA 246

Query: 1002 VPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMA 1061
             PL+  A +    + T +   +H  Q     L        TPP   A   L  + S  +A
Sbjct: 247  TPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305

Query: 1062 TAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVS 1121
            T    +  Q       Q P PT  + P    L    AT   + P        P+AP   S
Sbjct: 306  TPSPSAALQS------QAP-PTLPATPHSSSLTCQLATPLPLAPPS------PSAPP--S 350

Query: 1122 REEQALPRGLPGGWVTIQDGIYTAHPVRTFDP-PGGVQLSQREPQSRHRETALSVQAPRP 1180
             +    P   P    T   G  T     +F P P    L+   PQ+        +QAP  
Sbjct: 351  LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 1181 LQGGPGQST------------------GPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAA 1222
                P  S                    P    P    Q  + PP              A
Sbjct: 411  PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470

Query: 1223 ETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQ 1282
              +L   PL        P +  ASP P +    PPP  P  +  P         +     
Sbjct: 471  PPSLAAPPL------QVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 1283 ASEPLKDPLLHSHSSPAGQR--TPGGSQTKTPKLDPTMPPKKKP-------QLPPKPAHL 1333
            A+ PL+  L    +S  GQ   +P  S   +P   P  PP+  P       Q+PP P   
Sbjct: 524  ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATP--PPQAPPVLAAPLLQVPPSPPAS 580

Query: 1334 TQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSG 1393
                 P+R P P P                   DT++  P            P +R PS 
Sbjct: 581  PTLQAPRRPPTPGP-------------------DTSVSGPRLTLALAPGPPPPPSRSPSS 621

Query: 1394 H-SQPSL--QHGLSTTAPRPTKNQATG--SNAQSSEPPKLNALNHDPTSPQWGPGPSGEQ 1448
              S P L      +T+ P   +   +G    A +S PP        P +   GP P    
Sbjct: 622  TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP---- 677

Query: 1449 PMEGSHQGAPESP 1461
            P+  + +GAP +P
Sbjct: 678  PL--AFRGAPGAP 688



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 120/469 (25%), Positives = 159/469 (33%), Gaps = 98/469 (20%)

Query: 1104 RPGGGSDPRIPAAPRK---------VSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPP 1154
            RP G   P  P  P           V R+  A   G  GG  TI +    A P R+    
Sbjct: 28   RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG-ATIPESAPRAGPTRS---- 82

Query: 1155 GGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPG----KA 1210
                 S R P SR   +    +AP      PG  + PGR    G T+   GP G    + 
Sbjct: 83   --AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR--ASGTTRP--GPLGQKGLRI 136

Query: 1211 MAEVCPGGLQAAETTLKTA-PLGRHILASGP-------------QAAGAS---PHPHNAF 1253
             AE      +A E   ++A   G     SGP             +AAG     P P  + 
Sbjct: 137  SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196

Query: 1254 VPPPPT------------------LPAAVTGPDFPAGAHR-AEDSIQQASEPLKDPLLHS 1294
             P PPT                   PAA   P    G  R A  S+  ++ PL  P   +
Sbjct: 197  RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP---A 253

Query: 1295 HSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSF-- 1352
             S P+ + TP           P  P +      PKP  L    PPQ  P     +P+   
Sbjct: 254  RSGPSARGTPRA---------PAHPSQ------PKPKGLQALRPPQVTPPRKDAAPALGP 298

Query: 1353 --SSEVGQREHQRGERDTAIPQPAKVP-----TTVDQGHIPLARCPSGHSQPSLQHGLST 1405
              SS +         +  A P     P     T      +PLA  PS  + PSLQ   S 
Sbjct: 299  LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSLQTLPSP 357

Query: 1406 TAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQ 1465
             A  P  +QAT S    +     + L   P SP   P P     +      AP SP +  
Sbjct: 358  PATPP--SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA-- 413

Query: 1466 RNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAA 1514
                     L+ +     +A +++ V  L+  F   P     AP +P A
Sbjct: 414  ------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 84/332 (25%), Positives = 113/332 (34%), Gaps = 39/332 (11%)

Query: 948  PPADPSPVPASEGAQSLH-PTESIIHVPPLDPSMGMGHLRASGATP---CPPQAIGKAVP 1003
            PP  PS  P S+   SL  P   +   PP  P M         A P    PP  + K  P
Sbjct: 458  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517

Query: 1004 LAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATA 1063
             A  A A   LQ       S  GQ   +       +    P P AP +LAA   L++  +
Sbjct: 518  QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPS 576

Query: 1064 EAQSLHQQVLNKHKQGPTP---TATSNPIQDGLRKAGATQSNIRPGGG--SDPRIPAAPR 1118
               S     L   ++ PTP   T+ S P        G      R      S P +     
Sbjct: 577  PPAS---PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633

Query: 1119 KVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAP 1178
              +   + L RG   G     +G   A       PP   +L+   P +  R  A     P
Sbjct: 634  SATSTPEEL-RGYDSG----PEGGAAA------SPPPDAELAACHPAAWSRGPA----PP 678

Query: 1179 RPLQGGPG------QSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLG 1232
               +G PG       +TGPG  + G CT   +   G   A   PG L    +   +   G
Sbjct: 679  LAFRGAPGAPLPWPPATGPGSAD-GLCT--IYETEGPESATPAPGALDPGPSPGTSG--G 733

Query: 1233 RHILASGPQAAGASPHPHNAFVPPPPTLPAAV 1264
            +    +G  A+  SP        P   L A+V
Sbjct: 734  KAAAGAGAGASSRSPKQARLGELPLGALQASV 765



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 83/372 (22%), Positives = 133/372 (35%), Gaps = 42/372 (11%)

Query: 1383 GHIPLARCPSGHSQPSLQHGLSTTAPR--PTKNQATGSNAQSSEPPKLNALNHDPTSPQW 1440
            G  PLA    G    ++      +APR  PT++  T S   +S PP        P +   
Sbjct: 54   GRKPLAERAGGIGGATIPE----SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT 109

Query: 1441 GPGP-SGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFE 1499
             PGP S      G+ +  P     L+ + +E    + + +A E    S++   A R    
Sbjct: 110  SPGPVSSPGRASGTTRPGPLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSG 166

Query: 1500 AVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVHKALS 1559
              P        +PA  ++  A+            TEV   +    AR     E   K++S
Sbjct: 167  PTP-----GTPSPAMARRSRAA-----------GTEVGLPRPAPSARPRPPTEGPRKSVS 210

Query: 1560 SM---SSLQPEASAR-----GHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKN 1611
            S    S+ +P  +AR     G     P   S    +  +SS AR   S +      A  +
Sbjct: 211  SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270

Query: 1612 QAK---VECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPS 1668
            Q K   ++     Q     ++   A G  +S+  +T     + +   PP  LP++  S S
Sbjct: 271  QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP-TLPATPHSSS 329

Query: 1669 SPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQDIGQALLHQKGVQDKTGKKDITQCS 1728
                ++ Q AT  PL  PS    P +    +  A    QA         +     +    
Sbjct: 330  ----LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385

Query: 1729 VQPEPAPPSASP 1740
            + P   PP  +P
Sbjct: 386  LSPLATPPPQAP 397



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 80/413 (19%), Positives = 124/413 (30%), Gaps = 79/413 (19%)

Query: 1246 SPHPHNAFVPPPPTLPAA---------------------VTGPDFPAGAHRAEDSIQQAS 1284
            +P P  +  PPPP  PAA                     + G   P  A RA  + + A 
Sbjct: 26   TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT-RSAG 84

Query: 1285 EPLKDPLLHSHSSPAGQRTPGGSQTKTPKL------------------------DPTMPP 1320
               ++P     +S  G+R P    T    +                        + T+  
Sbjct: 85   TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144

Query: 1321 KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPA-----K 1375
             K  + P + A    +      P P   SP+ +     R  +    +  +P+PA     +
Sbjct: 145  GKATEAPKRSALSAGARRDTSGPTPGTPSPAMA-----RRSRAAGTEVGLPRPAPSARPR 199

Query: 1376 VPT-------TVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKL 1428
             PT       +    H      P+   +PS   GL   A R   + AT  ++ +   P  
Sbjct: 200  PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259

Query: 1429 NALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASS 1488
                  P  P   P P G Q +       P    +          L     +   ++ + 
Sbjct: 260  RGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318

Query: 1489 VDVQALRRLFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLL 1548
              + A         QL    P AP +   P +         T  S     L   TL    
Sbjct: 319  PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL---- 374

Query: 1549 DIEEAVHKALSS--MSSL------QPEASARGHFQGPPKDHSAHKISVTVSSS 1593
               +A H  L S  +S L       P A A    Q PP   ++  +S   + S
Sbjct: 375  ---QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 114/441 (25%), Positives = 152/441 (34%), Gaps = 66/441 (14%)

Query: 1079 GPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKV-------SREEQALPRGL 1131
            GP P   S P+  G   +G TQ  I+P       +P AP          + E   +PR  
Sbjct: 781  GPGPHYLSGPLPPGTY-SGPTQL-IQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSS 838

Query: 1132 PGGWVTIQD--GIYTAHPVRTFDPPGGVQLSQREPQSRHRE---TALSVQAPRPLQGGPG 1186
            P   V      G+  A PV         Q S  E     R    T  S+QAP P    P 
Sbjct: 839  PQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPR 898

Query: 1187 QSTGPGREEPGGCTQMAWGPPGKAMAE--VCPGG----LQAAETTLKTAPLGRHILASGP 1240
             +  P    P  C  +   PP + +      P G    + A        P G      GP
Sbjct: 899  PNPTPAPPPP--CFPV---PPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGP 953

Query: 1241 QAAG-ASPHPHNAFVPPPPTLPAAVTGPD-FP---AGAHRAEDSIQQASEP----LKDPL 1291
            Q      PHP  AF P PP  P  +  P  FP    G    +     A +P       P 
Sbjct: 954  QPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPP 1013

Query: 1292 LHSHSSPAGQRTPGGSQTKTPKLDPTMP-PKKKPQLPPKPAHLTQSHPPQRL--PKPLPL 1348
            LH+      Q  PG +Q   P     +P P   P  PP P       P  R   P+  PL
Sbjct: 1014 LHT------QLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPL 1067

Query: 1349 SPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHG-----L 1403
            +    S  GQ           +P PA  P     G +P  R P+    P L+ G     L
Sbjct: 1068 TIRGPSSAGQST----PSPHLVPSPAPSP---GPGPVP-PRPPAAEPPPCLRRGAAAADL 1119

Query: 1404 STTAPRPTK--NQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESP 1461
             +++P       Q+ G      +P K++A          G  P   + +E      PE  
Sbjct: 1120 LSSSPESQHGGTQSPGGGQPLLQPTKVDAAE--------GRRPQALRLIERDPYEHPERL 1171

Query: 1462 DSLQRNQKELQGLLNQVQALE 1482
              LQ+  +  +G L  V AL+
Sbjct: 1172 RQLQQELEAFRGQLGDVGALD 1192


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 164/788 (20%), Positives = 246/788 (31%), Gaps = 188/788 (23%)

Query: 947  EPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAG 1006
            +PP  P   P         P  S+    PL P + + H       P PPQ +     L  
Sbjct: 312  QPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHH----PSPPQGMHMPPQLET 367

Query: 1007 EAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQ 1066
                      T +Q       K + +    +G   TP       LL      R A    +
Sbjct: 368  PRMMMTPPPVTPQQP------KNIHINPHFKGTVVTPV---QVPLLPVPSQPRPAVGPQR 418

Query: 1067 SLHQQVLNKHKQGPTPTATSNP----IQDGLRKAGATQSN--IRPGGGSDPRIPAAPRKV 1120
                    +H  GP P + S P    +QD  R     Q       G   +PR P+    +
Sbjct: 419  FPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPS---HL 475

Query: 1121 SREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRP 1180
              E+++ P   P   +     + ++HPV T  P                   L    P P
Sbjct: 476  FLEQRSPPPPPPPPTL-----LNSSHPVPTQSP-------------------LPFTQPGP 511

Query: 1181 LQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGP 1240
                 GQ     RE P    + A  PPG                     P+G   +    
Sbjct: 512  AFNQQGQQPVFPRERP---VRPALQPPG---------------------PVG---ILHFS 544

Query: 1241 QAAGASPHPHNAFVPP-PPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPA 1299
            Q   A+  P   F+PP  P LP    GP                      P L +H+ P 
Sbjct: 545  QPGSATTRP---FIPPRQPFLP----GPG--------------------QPFLPTHTQPN 577

Query: 1300 GQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLP---KPLPLSPSFSSEV 1356
             Q          P   P  P  ++PQ  P P H     PP + P   +P P  P      
Sbjct: 578  LQ-----GPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHP--PQHP 630

Query: 1357 GQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQAT 1416
             Q +H       ++P P  +P                 SQP  +  + T  P     QA+
Sbjct: 631  PQHQHHHHHHHLSVPPPPLMPM----------------SQPQFRPHVQTAQP-----QAS 669

Query: 1417 GSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLN 1476
             S  Q    P+   L H+ TS         ++PM+     AP +      N +EL    +
Sbjct: 670  SSRMQC---PQRQGLRHNTTSQN-----VSKRPMQQMQPTAPRN-----SNLRELPIAPS 716

Query: 1477 QVQALEKEAASSVDVQALRRLFEAVPQLGGAA--------------PQAPAAHQKPEASV 1522
             V  +     S+     ++ +  A P     A              P +P A  K EA  
Sbjct: 717  HVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKT 776

Query: 1523 EQAFGE------LTRVSTEVAQLKEQTLARLLDIEEAVHKALSSMSSLQPEASARGHFQG 1576
            E  F +      L R+  E  +   + + +  ++             L+  A  +     
Sbjct: 777  ETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYA 836

Query: 1577 PP----KDHSAHKISVTVSSSARPSGSG---QEVGGQTAVKNQAKVECHTEAQSQVKIRN 1629
            PP    ++  A   S T  +   P       Q V  +  VKNQ            V I N
Sbjct: 837  PPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQ-----------DVSISN 885

Query: 1630 HTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRKP--LETPS 1687
                +  T++  PS+   +   + +   + L  +R  P S T    +    KP  +E P+
Sbjct: 886  ---VQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPA 942

Query: 1688 FKGNPDVS 1695
                P V+
Sbjct: 943  VPQTPRVA 950



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 50/194 (25%), Positives = 61/194 (31%), Gaps = 41/194 (21%)

Query: 1305 GGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRG 1364
            G  +   P L PT PP   PQ PP P    Q  P + L +P PL P     V    H   
Sbjct: 299  GRMKDHRPALLPTQPPVV-PQAPPPPPPPPQQQPIRSLFQPQPLQPLL--PVQHPHHPSP 355

Query: 1365 ERDTAIPQPAKVP-------------------------TTVDQGHIPLARCPSGHSQPSL 1399
             +   +P   + P                         T V    +PL   P   SQP  
Sbjct: 356  PQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVP---SQPRP 412

Query: 1400 QHGLSTTAPRPTKNQATGSNAQS--SEPPKLNALNHDPTSPQW--GPGPSGEQPMEGSHQ 1455
              G       P   Q T     +  S+PP+L      P   QW   P P    P      
Sbjct: 413  AVGPQRFPGPPEFPQHTPGPVPNSFSQPPRL------PLQDQWRAPPPPQDRDPFFLGVS 466

Query: 1456 GAPESPDSLQRNQK 1469
            G P  P  L   Q+
Sbjct: 467  GEPRFPSHLFLEQR 480


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 126/496 (25%), Positives = 161/496 (32%), Gaps = 108/496 (21%)

Query: 947  EPPADPSPVPAS---------EGAQS----LHPTESIIHVPPLDPSMGMGHLRASG---A 990
            E PA P+P PAS         E AQ+      PT  +   P L    G     +SG   A
Sbjct: 527  ELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586

Query: 991  TPCPPQAIGKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPP--GPGA 1048
            +P  PQ   K  P   E   P       K E            G   G T  PP  G G 
Sbjct: 587  SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPK----------GDGIGPTRQPPSQGLGY 636

Query: 1049 PDLLAAMQSLRMATAEAQSLHQQVLN---KHKQG---PTPTATSNPIQDGLRKAGATQSN 1102
            P    ++        + Q L QQ  +   +H+QG   PTP   S P    L    A Q  
Sbjct: 637  PKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQ-- 694

Query: 1103 IRPGGGSDPRIPAA--PRKVSREEQALPRGLPGGWVTI----QDGIYTAHPVRTFDPPG- 1155
                  + P  P A  P  + R     P      W+ I       +    P   F PPG 
Sbjct: 695  ------APPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV 748

Query: 1156 ---GVQLSQR--------EPQSRHRETALSVQAPRPLQ--------------GGPGQSTG 1190
               G+   +R        EP  RH    L  +   P+                 P   T 
Sbjct: 749  HPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808

Query: 1191 PGR-----EEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILAS-GPQAAG 1244
            P R     ++ G  ++    PP        PG     E      P+ R  L   GP+   
Sbjct: 809  PLRQAADEDDKGMRSETPPVPPPPPYLASYPG---FPENGAPGPPISRFPLEEPGPRPLP 865

Query: 1245 ASPHPHNAF---VPPPPTLP-----AAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHS 1296
              P          PPP   P     A +TGP+      R   S  Q   P   P   S +
Sbjct: 866  WPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPP---PRRESRT 922

Query: 1297 SPAGQRTPGGSQTKTPKLDPTMPPK-----KKP-------QLPPKPAHLTQSHPPQRLPK 1344
                   PG S+   P  +P  PP+     KKP       +LPPKP  L Q     + PK
Sbjct: 923  ETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKP--LEQGDETPKPPK 980

Query: 1345 PLPLSPSFSSEVGQRE 1360
            P PL  +     G +E
Sbjct: 981  PDPLKITKGKLGGPKE 996



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 121/508 (23%), Positives = 167/508 (32%), Gaps = 111/508 (21%)

Query: 987  ASGATPCPPQAIGKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGP 1046
            A+ +TP PP A+ K +P A  A  PA     E + +    +   A   +S   T TP   
Sbjct: 513  AAPSTPAPPPAVPKELP-APPAPPPASAPTPETEPE----EPAQAPPAQS---TPTPGVA 564

Query: 1047 GAPDLLA---AMQSLRMATAEAQSLHQQVLNKHKQGP---TPTATSNPIQ------DGLR 1094
             AP L++   +  S    + EA  +  Q+ +K    P    P  T+ P+       DG+ 
Sbjct: 565  AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI- 623

Query: 1095 KAGATQSNIRPGGGSDPRIPAAPRKVSR--EEQALPRGLPGGWVTIQDGIYTAHPVRTFD 1152
              G T+     G G      + P +  R  +EQ L +     W   Q G     PV    
Sbjct: 624  --GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV---- 677

Query: 1153 PPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGR-EEPGGCTQMAWGPPGKAM 1211
            PP         PQ        + QAP P    P ++  PG    P     M + P    +
Sbjct: 678  PPS-------PPQPVTLGAVPAPQAPPP----PPKALYPGALGRPPPMPPMNFDPRWMMI 726

Query: 1212 AEVCPGGLQAAETTLKTAPLGRHILASGPQ----AAGASPHPHNAFVP--------PPPT 1259
                   L      L   P G H     P+    + G+S  P +   P        PP  
Sbjct: 727  PPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVD 786

Query: 1260 LPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMP 1319
               A  G  F A              PL  PL       A      G +++TP + P  P
Sbjct: 787  PKLAWVGDVFTA--------TPAEPRPLTSPL-----RQAADEDDKGMRSETPPVPP--P 831

Query: 1320 PKKKPQLPPKPAHLTQSHPPQRL------PKPLPLSPSFSSEVGQREHQRGERDTAIPQP 1373
            P      P  P +     P  R       P+PLP  P  S EV                 
Sbjct: 832  PPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPG-SDEV----------------- 873

Query: 1374 AKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQA--TGSNAQSSEPPKLNAL 1431
            AK+ T            P    +P  +     T P   +  A   GS  Q   PP+    
Sbjct: 874  AKIQT------------PPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPR---- 917

Query: 1432 NHDPTSPQWGPGP-SGEQPMEGSHQGAP 1458
                T  +WGP P S  + +     GAP
Sbjct: 918  RESRTETRWGPRPGSSRRGIPPEEPGAP 945



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 64/267 (23%), Positives = 90/267 (33%), Gaps = 52/267 (19%)

Query: 1241 QAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAG 1300
            +A  A+P    +   PPP +P  +  P  P  A  A     +  EP + P   S  +P  
Sbjct: 505  KAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPA-SAPTPETEPEEPAQAPPAQSTPTPGV 563

Query: 1301 QRTP-----GGSQTKTPK-------LDPTMPPKKKPQ---------LPPKP--------A 1331
               P     GGS + T         ++P +P K+ P+          PP P         
Sbjct: 564  AAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI 623

Query: 1332 HLTQSHPPQRLPKP---LPLSPSFSSEVGQ-----------REHQRGERDTAIPQPAKVP 1377
              T+  P Q L  P     L P F  +  +           ++HQ+G      P P   P
Sbjct: 624  GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT-PVPPSPP 682

Query: 1378 TTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLN--ALNHDP 1435
              V  G +P  + P    +      L    P P  N           PP ++   L   P
Sbjct: 683  QPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMN---FDPRWMMIPPYVDPRLLQGRP 739

Query: 1436 TSPQWGPG--PSGEQPMEGSHQGAPES 1460
                + PG  PSG  P E S  G   S
Sbjct: 740  PLDFYPPGVHPSGLVPRERSDSGGSSS 766



 Score = 38.1 bits (87), Expect = 0.080
 Identities = 122/549 (22%), Positives = 173/549 (31%), Gaps = 91/549 (16%)

Query: 1006 GEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEA 1065
            G+  AP  +  T K   +  G  G AV G S             DL    + L   +  +
Sbjct: 1336 GDKEAPPPVLLTPKAVGTPGGGGGGAVPGIS--------AMSRGDLSQRAKDLSKRSFSS 1387

Query: 1066 QSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQ 1125
            Q    +  N+ + GP   A S+    G    G       PG G D R   +P+  SR  +
Sbjct: 1388 QRPGMERQNR-RPGPGGKAGSSGSSSG-GGGGGPGGRTGPGRG-DKRSWPSPKNRSRPPE 1444

Query: 1126 ALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGP 1185
              P GLP                     P G+Q +  +  SR          PR   G P
Sbjct: 1445 ERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLP 1504

Query: 1186 GQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGA 1245
                GP              PP +   +    GL +     +  P+ R +  +   +AG 
Sbjct: 1505 QAPQGPSPR-----------PPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGV 1553

Query: 1246 SPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPG 1305
            SP P      PP                 R  + +Q+ S P         S P G     
Sbjct: 1554 SPFPPKRRERPP-----------------RKPELLQEESLPPPHSSGFLGSKPEGPGPQA 1596

Query: 1306 GSQ-TKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRG 1364
             S+ T T  L P +  +       K        P    P   PLSP F    G    +  
Sbjct: 1597 ESRDTGTEALTPHIWNRLHTATSRK-----SYRPSSMEPWMEPLSP-FEDVAGT---EMS 1647

Query: 1365 ERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGS--NAQS 1422
            + D+ +       + V  G       P G        GL   A  P K     S  NA  
Sbjct: 1648 QSDSGVDLSG--DSQVSSGPCSQRSSPDG--------GLKGAAEGPPKRPGGSSPLNAVP 1697

Query: 1423 SE-PPKLNALNHDPTSPQWG------------PGPSGEQ------------PMEGSHQGA 1457
             E PP        P +P  G            PGP G +            P+  SH+  
Sbjct: 1698 CEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPG 1757

Query: 1458 PESPDSLQRNQKELQGLLNQVQALEKEAASSV-DVQALRRLFEAVPQLGGAA-PQA---P 1512
            P           +L+ ++      EKE  +SV +   + R +E +P    +A PQ+    
Sbjct: 1758 PPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLD 1817

Query: 1513 AAHQKPEAS 1521
            + H  PE S
Sbjct: 1818 SGHCVPEPS 1826



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 39/146 (26%), Positives = 50/146 (34%), Gaps = 40/146 (27%)

Query: 1306 GSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGE 1365
            G+  K  K +P  PP      P  PA      PP  +PK LP  P+              
Sbjct: 498  GAPDKRLKAEPAAPPAA----PSTPA------PPPAVPKELPAPPA-------------- 533

Query: 1366 RDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEP 1425
                 P PA  PT   +   P A+ P   S P+        A  PT     GS + +S  
Sbjct: 534  -----PPPASAPTPETEPEEP-AQAPPAQSTPT-----PGVAAAPTLVSGGGSTSSTSS- 581

Query: 1426 PKLNALNHDPTSPQWGPGPSGEQPME 1451
                +    P  PQ  P   G +P E
Sbjct: 582  ---GSFEASPVEPQL-PSKEGPEPPE 603


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
            preproprotein [Homo sapiens]
          Length = 331

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 95/402 (23%), Positives = 124/402 (30%), Gaps = 90/402 (22%)

Query: 1051 LLAAMQSLRMATAEAQSLHQQVLNKHK--------QGPTPTATSNPIQDGLRKAGATQSN 1102
            LL  +    +A + AQ+L++ V  +          QGP+P   + P   G          
Sbjct: 2    LLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKP--QGPPPPPGKPQG 59

Query: 1103 IRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQR 1162
              P GG+ P+ P  P K        P+G P        G  +  P     PPG       
Sbjct: 60   PPPQGGNKPQGPPPPGK--------PQGPP------PQGDKSRSPR---SPPG------- 95

Query: 1163 EPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAA 1222
            +PQ    +     Q P P    PG+  GP  +  GG       PPGK       G    +
Sbjct: 96   KPQGPPPQGGNQPQGPPP---PPGKPQGPPPQ--GGNRPQGPPPPGKPQGPPPQGDKSRS 150

Query: 1223 ETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPP--TLPAAVTGPDFPAGAHRAEDSI 1280
              +    P G      G Q  G  P P     PPP     P     P  P G     D  
Sbjct: 151  PRSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209

Query: 1281 QQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQ 1340
            + +  P           P G    GG+Q +     P  PP K    PP+  +  Q  PP 
Sbjct: 210  RSSQSP--------PGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQGPPPP 257

Query: 1341 RLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQ-PSL 1399
              P+  P      S+                                AR P G  Q P  
Sbjct: 258  GKPQGPPAQGGSKSQ-------------------------------SARSPPGKPQGPPQ 286

Query: 1400 QHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWG 1441
            Q G +   P P      G N Q  + P        P  PQ G
Sbjct: 287  QEGNNPQGPPP----PAGGNPQQPQAPPAGQPQGPPRPPQGG 324



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 66/245 (26%), Positives = 81/245 (33%), Gaps = 53/245 (21%)

Query: 1235 ILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHS 1294
            ++A  PQ  G SP   N    PPP  P    GP  P G ++                   
Sbjct: 31   LIAGNPQ--GPSPQGGNKPQGPPPP-PGKPQGPP-PQGGNK------------------- 67

Query: 1295 HSSPAGQRTPGGSQTKTPKLD----PTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSP 1350
               P G   PG  Q   P+ D    P  PP K    PP+  +  Q  PP   P   P  P
Sbjct: 68   ---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGP 121

Query: 1351 SFSSEVGQREHQRGERDTAIPQPAK---VPTTVDQGHIPLARCPSGHSQ-PSLQHGLSTT 1406
                       Q G R    P P K    P   D+   P  R P G  Q P  Q G    
Sbjct: 122  ---------PPQGGNRPQGPPPPGKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQ 170

Query: 1407 APRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEG-SHQGAPESPDSLQ 1465
             P P   +  G   Q  + P+       P     GP P G++     S  G P+ P    
Sbjct: 171  GPPPPPGKPQGPPPQGGKKPQ----GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226

Query: 1466 RNQKE 1470
             NQ +
Sbjct: 227  GNQPQ 231



 Score = 39.7 bits (91), Expect = 0.027
 Identities = 53/185 (28%), Positives = 60/185 (32%), Gaps = 27/185 (14%)

Query: 948  PPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGK--AVPLA 1005
            PP  P   P   G Q           PP  P    G     G  P  P   GK    P  
Sbjct: 154  PPGKPQGPPPQGGNQP--------QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205

Query: 1006 GEAAAPAQLQNTEKQEDSHSG----QKGMAVLGKSEGATTT-------PPGPGAPDLLAA 1054
            G+ +  +Q    + Q     G    Q      GK +G           PP PG P    A
Sbjct: 206  GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPA 265

Query: 1055 M-----QSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGS 1109
                  QS R    + Q   QQ  N + QGP P A  NP Q     AG  Q   RP  G 
Sbjct: 266  QGGSKSQSARSPPGKPQGPPQQEGN-NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 324

Query: 1110 DPRIP 1114
             P  P
Sbjct: 325  RPSRP 329



 Score = 38.5 bits (88), Expect = 0.061
 Identities = 59/237 (24%), Positives = 74/237 (31%), Gaps = 58/237 (24%)

Query: 1307 SQTKTPKL------DPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQRE 1360
            SQ ++P L       P+     KPQ PP P    Q  PPQ   KP    P          
Sbjct: 24   SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP--------- 74

Query: 1361 HQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQ-PSLQHGLSTTAPRPTKNQATGSN 1419
                       +P   P   D+   P  R P G  Q P  Q G     P P   +  G  
Sbjct: 75   ----------GKPQGPPPQGDKSRSP--RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 122

Query: 1420 AQSSEPPKLNALNHDPTSPQWGPGPSGEQ---PMEGSHQGAPESPDSLQRNQKELQGLLN 1476
             Q    P+             GP P G+    P +G    +P SP    +      G  N
Sbjct: 123  PQGGNRPQ-------------GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG--N 167

Query: 1477 QVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVS 1533
            Q Q                   +  P  GG  PQ P    KP+    Q  G+ +R S
Sbjct: 168  QPQGPPPPPGKP----------QGPPPQGGKKPQGPPPPGKPQGPPPQ--GDKSRSS 212


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 115/442 (26%), Positives = 154/442 (34%), Gaps = 98/442 (22%)

Query: 946  WEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLA 1005
            W+PP  P P       + + P  +    PP +   G    R  G T    +A G A P A
Sbjct: 171  WKPPP-PLPSERQPADRRITPALATPASPPTESQAGP---RNQGQTA--GRARGGAPPHA 224

Query: 1006 GEA--AAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLR---- 1059
            GE   A PA         DS SG   +  +      +  PP   A   LAA  SL     
Sbjct: 225  GEGEMAQPA---------DSESGLSLLCKITFKSRPSLAPPA--ASSSLAAKASLGGGGG 273

Query: 1060 --MATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGG-SDPRIPAA 1116
              +  A     + +VL   KQGP P   + P+ +  R A   +     G G S P  P+A
Sbjct: 274  GGLFAASGAISYAEVL---KQGPLPPGAARPLGEVSRGAQEAEGGDGDGEGCSGP--PSA 328

Query: 1117 PRKVSREEQALP----RGLPGG-----WVTIQDGIYTAHPVRTF---DPPGGVQLSQREP 1164
            P   +R   ALP       PG      WV+  DG     P R F      GG+   +R  
Sbjct: 329  PASQAR---ALPPPPYTTFPGSKPKFDWVSAPDG-----PERHFRFNGAGGGIGAPRR-- 378

Query: 1165 QSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAET 1224
                R  ALS         GP  S  P  E+       A GP   A A      L A  T
Sbjct: 379  ----RAAALS---------GPWGSPPPPPEQ----IHSAPGPRRPAPA------LLAPPT 415

Query: 1225 TLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQAS 1284
             +  AP     +  GP      P        PPPT P  +  P           ++Q   
Sbjct: 416  FIFPAPTNGEPMRPGPPGLQELP------PLPPPTPPPTLQPP-----------ALQPTP 458

Query: 1285 EPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPK 1344
             P+  PL    +   G +    + T  P L P +   + P   P PA  T + P   +  
Sbjct: 459  LPVAPPL----TPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAP-TVAEPSPPVSA 513

Query: 1345 PLPLSPSFSSEVGQREHQRGER 1366
            P P +    +   + +  R  R
Sbjct: 514  PAPAAAPIKTRTRRNKGSRAAR 535



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 92/412 (22%), Positives = 125/412 (30%), Gaps = 83/412 (20%)

Query: 1081 TPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQD 1140
            TP +     Q G R  G T    R G         AP      E A P     G   +  
Sbjct: 194  TPASPPTESQAGPRNQGQTAGRARGG---------APPHAGEGEMAQPADSESGLSLLCK 244

Query: 1141 GIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCT 1200
              + + P  +  PP                ++L+ +A     GG G     G        
Sbjct: 245  ITFKSRP--SLAPPAA-------------SSSLAAKASLGGGGGGGLFAASGAISYAEVL 289

Query: 1201 QMAWGPPGKA--MAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPP 1258
            +    PPG A  + EV  G  +A          G     SGP +A AS       +PPPP
Sbjct: 290  KQGPLPPGAARPLGEVSRGAQEAEGGD------GDGEGCSGPPSAPAS---QARALPPPP 340

Query: 1259 --TLPAA------VTGPDFPAGAHRAEDSIQQASEPLK-------------DPLLHSHSS 1297
              T P +      V+ PD P    R   +      P +              P    HS+
Sbjct: 341  YTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSGPWGSPPPPPEQIHSA 400

Query: 1298 PAGQRTPGGSQTKTPKLDPTMPPKKKPQLP-----------PKPAHLTQSHPPQRLPKPL 1346
            P G R P  +    P      P   +P  P           P P       PP   P PL
Sbjct: 401  P-GPRRPAPALLAPPTFIFPAPTNGEPMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPL 459

Query: 1347 PLSPSFSSEVGQREHQRGER------------DTAIPQPAKVPTTVDQGHIPLARCPSGH 1394
            P++P  +  +G +E                      P PA  PT  +    P    P+  
Sbjct: 460  PVAPPLTPGLGHKESALAPTAAPALPPALAADQAPAPSPAPAPTVAEPS--PPVSAPAPA 517

Query: 1395 SQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSG 1446
            + P           R  +  AT  +    + P+  A    P S   G G SG
Sbjct: 518  AAPIKTRTRRNKGSRAARG-ATRKDGLHGDGPRERATATVPDSSGGGGGGSG 568



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 54/235 (22%), Positives = 83/235 (35%), Gaps = 31/235 (13%)

Query: 1097 GATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGG 1156
            G  QS    GGGS    P+     SR    +   +    + +  G+    P  +  PPG 
Sbjct: 2    GNLQSEPSAGGGSRKVQPSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFP-GSATPPG- 59

Query: 1157 VQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCP 1216
              +  REPQ+      L+++ P P+   P ++                 PP      + P
Sbjct: 60   -LMVPREPQASPSTLPLTLERPSPVMPPPEEAAAVS------------APPPAPAGTLLP 106

Query: 1217 GGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPP-TLPAAVTGPDFPAGAHR 1275
            G  +  +      P  R +L +  +  G  P       PPPP  L    T P  P+    
Sbjct: 107  GPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPS---- 162

Query: 1276 AEDSIQQASEPLK----DPLLHSHSSPAGQR-TPGGSQTKTPKLDPTMPPKKKPQ 1325
                  Q   PL+     P L S   PA +R TP  +   +P  +    P+ + Q
Sbjct: 163  ------QFPPPLETWKPPPPLPSERQPADRRITPALATPASPPTESQAGPRNQGQ 211



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 62/229 (27%), Positives = 76/229 (33%), Gaps = 42/229 (18%)

Query: 1157 VQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCP 1216
            VQ S R P SR      S+  P         + G G   PG  T     PPG  +    P
Sbjct: 17   VQPSDRAPDSRRT----SLVEPEMTSQAMRLTRGLGVWFPGSAT-----PPGLMV----P 63

Query: 1217 GGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRA 1276
               QA+ +TL   PL               P P    V PPP   AAV+ P  PA A   
Sbjct: 64   REPQASPSTL---PLTLE-----------RPSP----VMPPPEEAAAVSAPP-PAPAGTL 104

Query: 1277 EDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQS 1336
                 +  +P   P+              G       L P  PP++       P   +Q 
Sbjct: 105  LPGPSKWQKPAGTPVPRIRRLLEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQF 164

Query: 1337 HPPQRLPKPLPLSPSFSSEVGQREHQRGER--DTAIPQPAKVPTTVDQG 1383
             PP    KP P  PS        E Q  +R    A+  PA  PT    G
Sbjct: 165  PPPLETWKPPPPLPS--------ERQPADRRITPALATPASPPTESQAG 205


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
            homolog 2 [Homo sapiens]
          Length = 1210

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 117/525 (22%), Positives = 194/525 (36%), Gaps = 57/525 (10%)

Query: 1257 PPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPK--- 1313
            PP+ P ++  P   A +  AE      S+   D    S SS + +  P  +    P+   
Sbjct: 450  PPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPT 509

Query: 1314 -----LDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDT 1368
                 LD  +    +P  PP+    T+  PP+R P+    S S +S+    EH    +D 
Sbjct: 510  TNKWQLDNWLTKVSQPAAPPEGPRSTE--PPRRHPESKGSSDSATSQ----EHSES-KDP 562

Query: 1369 AIPQPAKVPTTVDQGHIPLAR-CPSGHSQ--PSLQHGLSTTAPR-PTKNQATGSNAQS-- 1422
                 +K P    +   P  R C    +Q  P  +  + T  P+ P K  A   +  S  
Sbjct: 563  PPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQ 622

Query: 1423 --SEPPKLNALNHDPTSPQWGPGPSGEQPMEG-SHQGAPESPDSLQRNQKELQGLLNQVQ 1479
               EP  L   + D TS       +  +P    S++  P  P S ++ +K    L    +
Sbjct: 623  GEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEK-KKHKSSLPAPSK 681

Query: 1480 ALEKEAASSVDVQ-ALRRLFEAVPQLGGAAPQAPAAHQKP----EASVEQAFGELTRVST 1534
            AL     +  +V+      F  VP      P    +  +     +A V Q      R+  
Sbjct: 682  ALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPL 741

Query: 1535 EVAQLKEQTLARLLDI---EEAVHKALSSMSSLQPEASARGHFQG------PP--KDHSA 1583
             +   K   L+ L D    +  + K    + S  P+   +G  Q       PP  K HS+
Sbjct: 742  PLRDTK--LLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSS 799

Query: 1584 HKISVTVSSSARPSGSGQEVGGQTAVKNQAKVECHTEAQSQVKIRNHTEARGHTASTAPS 1643
             K S   SS       G+    +     + ++E   ++QS     +H E+    + T PS
Sbjct: 800  EKRSSDSSSKLAKKRKGE--AERDCDNKKIRLEKEIKSQSSSSSSSHKES----SKTKPS 853

Query: 1644 TRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRKPLETPSFKGNPDVSVKSTQLAQ 1703
                ++S++ + PP  + SS   P+ P      +  R   E  +   +P  S  ST+ + 
Sbjct: 854  RPSSQSSKKEMLPPPPVSSSSQKPAKP------ALKRSRREADTCGQDPPKSASSTK-SN 906

Query: 1704 DIGQALLHQKGVQDKTGKKDITQCSVQPEPAPPSASP-LPRGWQK 1747
                ++  Q+ V+ K  +          + A P   P LP G  K
Sbjct: 907  HKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSK 951


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 147/604 (24%), Positives = 205/604 (33%), Gaps = 94/604 (15%)

Query: 876  PELQQLLACGL--GTSVARTGLVMQETEQGLVALTAYSLQPRLTSKASERSSVQLLASCI 933
            P   Q +A G   G + A +G        G V L    LQP    KA   + VQ +   +
Sbjct: 775  PPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGI--LQPGALGKAGGITQVQYILPTL 832

Query: 934  DKGDLSGLHSLRWEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPC 993
             +        L+  P   P+P   +       PT SI    P   S     L A+  TP 
Sbjct: 833  PQ-------QLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPG 885

Query: 994  PP--QAIGKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDL 1051
             P  Q++  A P   ++ +P Q            G+    VL      + +  G GA   
Sbjct: 886  IPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGK----VLVPLAAPSMSVRGGGAGQP 941

Query: 1052 LAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDP 1111
            L  +      +   Q+  Q      +  P P +T + +   L  A        PG  S P
Sbjct: 942  LPLVSP--PFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATL------PGPTSQP 993

Query: 1112 R---IPAAPRKVSREEQALPRGLPGGW--VTIQDGIYTAHPVRTFDPPGGVQLSQREPQS 1166
            +   +P++ R ++  + A    LP G    + Q G  T++   +    G   L    P  
Sbjct: 994  QKVLLPSSTR-ITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPA- 1051

Query: 1167 RHRETALSV-QAPRPLQGGPGQSTGPGREEPGGC--------TQMAWGPPGKAMAEVCPG 1217
               +  LS  QAP    G  G S  P  + P  C        T    G P    +     
Sbjct: 1052 -FVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQ 1110

Query: 1218 GLQAAETTL-----KTAPLGRHILASGPQA-AGASPHPHNAFVP---------------- 1255
              QA  + +      T P    IL  GP A A A+P P + F                  
Sbjct: 1111 PSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQ 1170

Query: 1256 -PPPTLP-------AAVTGPDFPAGAH-RAEDSIQQASEP--LKDPLLHSHSSPAGQRTP 1304
             P P  P       A++    F AGA  R   + +Q  EP  +++P     S   GQ TP
Sbjct: 1171 RPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTA-PESELEGQPTP 1229

Query: 1305 GGSQTKTPKLDPTMPP--KKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQ 1362
                   P L  T  P  +  P LPP     T +  P+ +    P S S     GQ    
Sbjct: 1230 PAP----PPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLEN 1285

Query: 1363 RGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQS 1422
            RGE  T  P PA  P          A  P G S+ S       T P   +   TG   + 
Sbjct: 1286 RGEPPTP-PSPAPAP----------AVAPGGSSESSSGRAAGDT-PERKEAAGTGKKVKV 1333

Query: 1423 SEPP 1426
              PP
Sbjct: 1334 RPPP 1337



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 129/602 (21%), Positives = 184/602 (30%), Gaps = 135/602 (22%)

Query: 966  PTESIIHVPPLDP------SMGMGHLRASGATPCPPQAIGKAVPLAGEA-AAPAQLQNTE 1018
            P  S+ +  P  P      +M    +R   +TP P     K  P +G A A+P       
Sbjct: 651  PAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVP--IASKPFPTSGRAEASPNDTAGAR 708

Query: 1019 KQEDSHSGQKGMAVLG-------KSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQ 1071
             +  + S   G + LG       K   A T+P    AP L+A      +  A A   +  
Sbjct: 709  TEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP----APHLVAGPLLGTVGKAPATVTNLL 764

Query: 1072 VLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPR------------------- 1112
            V       P P A     Q      G T +    G GS P                    
Sbjct: 765  VGTPGYGAPAPPAVQFIAQGA--PGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGI 822

Query: 1113 ------IPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQS 1166
                  +P  P+++  +    P   PG       G      +R   PPG          +
Sbjct: 823  TQVQYILPTLPQQL--QVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPG----------T 870

Query: 1167 RHRETALSVQAPRP----LQGGPG------QSTGPGREEP-GGCTQMAWGPPGKAMAEVC 1215
                  L+  AP P    LQ  P       QS  P +  P GG  Q+    PGK +    
Sbjct: 871  STNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLL---PGKVLVP-- 925

Query: 1216 PGGLQAAETTLKTAPLGRHI-LASGP-----QAAGASPHPHNAFVPPPPTLPAAVTGPDF 1269
               L A   +++    G+ + L S P     Q     P       P P + P+ +  P  
Sbjct: 926  ---LAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLS 982

Query: 1270 PAGAHRAEDSIQQASEPLKDPLLH-----SHSSPAGQRTPGGSQTKT------------- 1311
            PA         Q+   P    + +      H+ P G  +P  SQ  T             
Sbjct: 983  PATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGT-SPASSQAGTVTSYGPTSSVALG 1041

Query: 1312 -PKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVG-------QREHQR 1363
               L P+ P   +P L    A L         P P P  P   +  G             
Sbjct: 1042 FTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPA 1101

Query: 1364 GERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTK---NQATGSNA 1420
                  + QP++ P ++          P+    P      +T  P PT    +   GS  
Sbjct: 1102 PTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMT 1161

Query: 1421 QSSEPPKLNALNHDPTSPQ-------------------WGPGPSGEQPMEGSHQGAPESP 1461
             S   PK  A    P +PQ                     PGP+  QP+E      P +P
Sbjct: 1162 YSLVAPK--AQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAP 1219

Query: 1462 DS 1463
            +S
Sbjct: 1220 ES 1221


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 82/328 (25%), Positives = 116/328 (35%), Gaps = 46/328 (14%)

Query: 1079 GPTPTATSNPIQDGLRKAGATQSNIRPGGGS-DPRIPAAPRKVSREEQALPRGLPGGWVT 1137
            G  P       Q G+ K  +T +     GGS  P +P   R  S +  + P G PG +  
Sbjct: 94   GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSG-PGRFPV 152

Query: 1138 IQDGIYTA--HPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREE 1195
               G  +    P R   PP    +  + P S           PRP+Q  P     P    
Sbjct: 153  PSPGHRSGPPEPQRNRMPPPRPDVGSK-PDSIPPPVP---STPRPIQSSPHNRGSP--PV 206

Query: 1196 PGGCTQMAWGP-----PGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAA------- 1243
            PGG  Q + GP     PG     +  G ++ +  +  +    R  L   P  A       
Sbjct: 207  PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 1244 -----GASPHPHNAFVPPPP---TLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSH 1295
                 G  P  H   VPPPP     P   + P  P+ + +A       S P   PL  S 
Sbjct: 267  PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 1296 S-SPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPK----PLPLSP 1350
            S +    R P  + + +    P   P +   LPP P+   +  PP R P     PLP  P
Sbjct: 326  SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE--RPPPPVRDPPGRSGPLPPPP 383

Query: 1351 SFSSEVGQREHQRGERDTAIPQPAKVPT 1378
              S        + G    A+P   ++P+
Sbjct: 384  PVS--------RNGSTSRALPATPQLPS 403



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 68/276 (24%), Positives = 98/276 (35%), Gaps = 45/276 (16%)

Query: 1255 PPPPTLPAAVTGPDFPAGAHRAEDSIQQASE-PLKDPLLHSHSSPAGQRTPGGSQTKTPK 1313
            PP P+ P  +       G+       +Q S  P   P   +  +  G    GGS  ++P 
Sbjct: 185  PPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG----GGSIRQSP- 239

Query: 1314 LDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQP 1373
            L  + P   +P LPP P+      PP   P P+   PS   E             A+P P
Sbjct: 240  LSSSSPFSNRPPLPPTPSRALDDKPPPP-PPPVGNRPSIHRE-------------AVPPP 285

Query: 1374 AKVPTTVDQGHIPLARCPSGHSQ-PSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALN 1432
               P   ++  +P    PS  SQ P      S   P P    ++G N ++   P+ N   
Sbjct: 286  ---PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG-NDETPRLPQRNLSL 341

Query: 1433 HDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQ 1492
               T P   PG SG  P   S +  P   D   R+     G L     + +  ++S    
Sbjct: 342  SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-----GPLPPPPPVSRNGSTS---- 392

Query: 1493 ALRRLFEAVPQLGG--------AAPQAPAAHQKPEA 1520
               R   A PQL          + P+ P    +P A
Sbjct: 393  ---RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 44/191 (23%), Positives = 60/191 (31%), Gaps = 33/191 (17%)

Query: 1266 GPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTP----GGSQTKTPKLDPTMPPK 1321
            G  F  G       + QA  P      +  +   G R P    GG  T      P   P 
Sbjct: 89   GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148

Query: 1322 KKPQLPPKPAHLTQSHPPQR--LPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTT 1379
            + P   P P H +    PQR  +P P P       +VG +             P  +P  
Sbjct: 149  RFPV--PSPGHRSGPPEPQRNRMPPPRP-------DVGSK-------------PDSIPPP 186

Query: 1380 VDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTK-----NQATGSNAQSSEPPKLNALNHD 1434
            V     P+   P     P +  G    +P PT      N+ T     S     L++ +  
Sbjct: 187  VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246

Query: 1435 PTSPQWGPGPS 1445
               P   P PS
Sbjct: 247  SNRPPLPPTPS 257


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
            sapiens]
          Length = 503

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 82/328 (25%), Positives = 116/328 (35%), Gaps = 46/328 (14%)

Query: 1079 GPTPTATSNPIQDGLRKAGATQSNIRPGGGS-DPRIPAAPRKVSREEQALPRGLPGGWVT 1137
            G  P       Q G+ K  +T +     GGS  P +P   R  S +  + P G PG +  
Sbjct: 94   GGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSG-PGRFPV 152

Query: 1138 IQDGIYTA--HPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREE 1195
               G  +    P R   PP    +  + P S           PRP+Q  P     P    
Sbjct: 153  PSPGHRSGPPEPQRNRMPPPRPDVGSK-PDSIPPPVP---STPRPIQSSPHNRGSP--PV 206

Query: 1196 PGGCTQMAWGP-----PGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQAA------- 1243
            PGG  Q + GP     PG     +  G ++ +  +  +    R  L   P  A       
Sbjct: 207  PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 1244 -----GASPHPHNAFVPPPP---TLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSH 1295
                 G  P  H   VPPPP     P   + P  P+ + +A       S P   PL  S 
Sbjct: 267  PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 1296 S-SPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPK----PLPLSP 1350
            S +    R P  + + +    P   P +   LPP P+   +  PP R P     PLP  P
Sbjct: 326  SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE--RPPPPVRDPPGRSGPLPPPP 383

Query: 1351 SFSSEVGQREHQRGERDTAIPQPAKVPT 1378
              S        + G    A+P   ++P+
Sbjct: 384  PVS--------RNGSTSRALPATPQLPS 403



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 68/276 (24%), Positives = 98/276 (35%), Gaps = 45/276 (16%)

Query: 1255 PPPPTLPAAVTGPDFPAGAHRAEDSIQQASE-PLKDPLLHSHSSPAGQRTPGGSQTKTPK 1313
            PP P+ P  +       G+       +Q S  P   P   +  +  G    GGS  ++P 
Sbjct: 185  PPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALG----GGSIRQSP- 239

Query: 1314 LDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQP 1373
            L  + P   +P LPP P+      PP   P P+   PS   E             A+P P
Sbjct: 240  LSSSSPFSNRPPLPPTPSRALDDKPPPP-PPPVGNRPSIHRE-------------AVPPP 285

Query: 1374 AKVPTTVDQGHIPLARCPSGHSQ-PSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALN 1432
               P   ++  +P    PS  SQ P      S   P P    ++G N ++   P+ N   
Sbjct: 286  ---PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG-NDETPRLPQRNLSL 341

Query: 1433 HDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVDVQ 1492
               T P   PG SG  P   S +  P   D   R+     G L     + +  ++S    
Sbjct: 342  SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS-----GPLPPPPPVSRNGSTS---- 392

Query: 1493 ALRRLFEAVPQLGG--------AAPQAPAAHQKPEA 1520
               R   A PQL          + P+ P    +P A
Sbjct: 393  ---RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSA 425



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 44/191 (23%), Positives = 60/191 (31%), Gaps = 33/191 (17%)

Query: 1266 GPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTP----GGSQTKTPKLDPTMPPK 1321
            G  F  G       + QA  P      +  +   G R P    GG  T      P   P 
Sbjct: 89   GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPG 148

Query: 1322 KKPQLPPKPAHLTQSHPPQR--LPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTT 1379
            + P   P P H +    PQR  +P P P       +VG +             P  +P  
Sbjct: 149  RFPV--PSPGHRSGPPEPQRNRMPPPRP-------DVGSK-------------PDSIPPP 186

Query: 1380 VDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTK-----NQATGSNAQSSEPPKLNALNHD 1434
            V     P+   P     P +  G    +P PT      N+ T     S     L++ +  
Sbjct: 187  VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246

Query: 1435 PTSPQWGPGPS 1445
               P   P PS
Sbjct: 247  SNRPPLPPTPS 257


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 101/439 (23%), Positives = 144/439 (32%), Gaps = 36/439 (8%)

Query: 948  PPADPSPVPASEGAQSLHP----------TESIIHVPPLDPSMGMGHLRASGATPCPPQA 997
            PP  P  VPA+ G  SL P          T  +   P L  S   GH      T      
Sbjct: 1478 PPLAPV-VPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPG 1536

Query: 998  IGKAV-PLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQ 1056
            +   V P       PA    +      +      ++L  +  A+     P AP  +AA Q
Sbjct: 1537 LNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAP--MAAPQ 1594

Query: 1057 SLRMATAEAQSLHQQVLNKHKQGPTPTATSN----PIQDGLRKAGATQSNIRPGGGSDPR 1112
            +  +A + A  L    +     G  P   S+    P+       G + ++  P     P 
Sbjct: 1595 TAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654

Query: 1113 I-PAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRET 1171
            + P++ + +       P   P    T+      A  +    P   + L    PQ      
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714

Query: 1172 ALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAET-TLKTAP 1230
             LS+     L   P Q+       P G TQ     P   +A   P G   A T TL  A 
Sbjct: 1715 TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS 1774

Query: 1231 LGRHILA-SGPQAAGASPHPHNAFVPPPP-TLPAAVTGPDFPAGAHRAEDSIQQASEPLK 1288
                +LA +  Q    SP P     P    TL  A      PA   +A   +  AS    
Sbjct: 1775 SSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPAS--QASSLVVSASGAAP 1832

Query: 1289 DPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPL 1348
             P+      P  +  P            T+  +  P  PP  A       P+R P P P 
Sbjct: 1833 LPVTMVSRLPVSKDEPD-----------TLTLRSGPPSPPSTATSFGGPRPRRQPPPPPR 1881

Query: 1349 SPSFSSEVGQ-REHQRGER 1366
            SP +   + + R+ QR ER
Sbjct: 1882 SPFYLDSLEEKRKRQRSER 1900



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 49/181 (27%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 1239 GPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSP 1298
            GP+ + A P P     P P  LPA++     PAG      S  +   P+  P L  +S  
Sbjct: 1029 GPELS-AQPTPG----PVPQVLPASLMVSASPAGPPLIPAS--RPPGPVLLPPLQPNSGS 1081

Query: 1299 AGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPP--QRLPKPLPLSPSF---- 1352
              Q  P      +    P  P       PP P  L+ + PP    L KPL + P +    
Sbjct: 1082 LPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPP 1141

Query: 1353 SSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTK 1412
            ++             TA+P P   P  +       AR PSG      Q  L++ A RP  
Sbjct: 1142 AAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQ--LASLAQRPVA 1199

Query: 1413 N 1413
            N
Sbjct: 1200 N 1200



 Score = 39.7 bits (91), Expect = 0.027
 Identities = 117/575 (20%), Positives = 185/575 (32%), Gaps = 117/575 (20%)

Query: 943  SLRWEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGM--GHLRASGATPCPPQAIGK 1000
            SL   PP D  PV      + L  +E  + + P  PS+ +  G +        P  A G 
Sbjct: 2576 SLSLVPPKDLLPV----AVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGT 2631

Query: 1001 AVPLAGEAAA-------------PAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPG 1047
             + +  E                P    + E  ++     +    L +++  T++P  P 
Sbjct: 2632 TLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKP- 2690

Query: 1048 APDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGG 1107
                    Q L  A   A S      +   +GP+P           R+  +    IR  G
Sbjct: 2691 --------QELVTAEVAAPSTSSSATSS-PEGPSPARPP-------RRRTSADVEIRGQG 2734

Query: 1108 GSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSR 1167
               P  P  P+ +        R LPG  VT+ +                 +L +R  Q R
Sbjct: 2735 TGRPGQPPGPKVL--------RKLPGRLVTVVEE---------------KELVRRRRQQR 2771

Query: 1168 HRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLK 1227
               + L       + G    S  PG       +     PP     E  P       ++L 
Sbjct: 2772 GAASTL-------VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPS------SSLP 2818

Query: 1228 TAP----LGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQA 1283
            T P    + R  +  G    G+  +   A +   P  PA       P   +R+     + 
Sbjct: 2819 TPPQQPFIARRHIELGVTGGGSPENGDGALLAITP--PAVKRRRGRPPKKNRSPADAGRG 2876

Query: 1284 SEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLP 1343
             +        + SS    +T G      P+      P  +PQL P P  L     PQ + 
Sbjct: 2877 VD-------EAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLG----PQPVH 2925

Query: 1344 KPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHI----------------PL 1387
            +P PL     S V +R   R  +   +P P  + +  D                    PL
Sbjct: 2926 RPNPLL----SPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPL 2981

Query: 1388 ARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTS--PQWGPGPS 1445
              CP+     ++     +T+P   K      N  S  P +L  L+ D TS     G G  
Sbjct: 2982 LVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRR 3041

Query: 1446 GEQPMEGSHQGAPESPDS------LQRNQKELQGL 1474
             +   +G  +G+    D       L R + E +G+
Sbjct: 3042 RQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGM 3076



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 146/631 (23%), Positives = 201/631 (31%), Gaps = 92/631 (14%)

Query: 995  PQAIGKAVPLAGEAAAPAQLQNT--EKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLL 1052
            P   G ++PLA     P  + NT   K     + + G+  +     A   PP  G P +L
Sbjct: 1284 PAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPA-PRPPSSGLPAVL 1342

Query: 1053 AAMQSLRMATAEAQSLHQQVLNKHKQGPTPTAT-SNPIQDGLRKAGATQSNIRPGGGSDP 1111
                +L        +L         + P PT T   P+   +       S   PG     
Sbjct: 1343 NPRPTLTPGRLPTPTLGT------ARAPMPTPTLVRPLLKLVHSPSPEVSASAPG----- 1391

Query: 1112 RIPAAPRKVSREEQALPRGLPG---GWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRH 1168
               AAP  +S     +P  LPG     + I +    A PV +      V LS   P S  
Sbjct: 1392 ---AAPLTIS-SPLHVPSSLPGPASSPMPIPNSSPLASPVSS---TVSVPLSSSLPIS-- 1442

Query: 1169 RETALSVQAPRPLQGGPGQSTGPGREEPGGCTQM----------AWGPPGKAMAEVCPGG 1218
              T L   A  PL              P   T +          A GPP  A +   P  
Sbjct: 1443 VPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA 1502

Query: 1219 LQAAETTLKTAPLGRHILASGPQAAGASPHPH----NAFVPP---PPTLPAAVTGPDFPA 1271
              A    L TAP        G     A    H    N+ V P   P  +PA+     FP+
Sbjct: 1503 -SALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPS 1561

Query: 1272 GAHRAEDS------IQQASEPLKDPLLHSHS--------SPAGQRTPGGSQTKTPKLDPT 1317
              + A            AS+ L  PL    +        SPA    P      +P   P 
Sbjct: 1562 APNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPV 1621

Query: 1318 MPPKKK--PQLPPKPAHLTQSHPPQRLPKPLP-LSPSFSSEVGQREHQRGERDTAIPQPA 1374
            +   +   P + P     T       +P P P L+PS +  +             +P P 
Sbjct: 1622 LASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTM---------LPAPVPSPL 1672

Query: 1375 KVPTTVDQGHIPLARCPS-GHSQPSLQHGLSTTAPR---PTKNQATGSNAQSSEPPKLNA 1430
              P +     +  A  P+ G S PS    L T  P+   PT+  +  + A S  P     
Sbjct: 1673 PSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSL-TPASSLVPTPAQT 1731

Query: 1431 LNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASSVD 1490
            L+  P  P    GP+    +  +   AP SP            L     +      +   
Sbjct: 1732 LSLAPGPPL---GPTQTLSLAPAPPLAPASP----VGPAPAHTLTLAPASSSASLLAPAS 1784

Query: 1491 VQALRRLFEAVPQLGGAAPQ----APAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLAR 1546
            VQ L      VP LG AA Q    APA+ Q P +           VS   A     T+  
Sbjct: 1785 VQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLV-----VSASGAAPLPVTMVS 1839

Query: 1547 LLDIEEAVHKALSSMSSLQPEASARGHFQGP 1577
             L + +     L+  S      S    F GP
Sbjct: 1840 RLPVSKDEPDTLTLRSGPPSPPSTATSFGGP 1870



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 73/348 (20%), Positives = 116/348 (33%), Gaps = 79/348 (22%)

Query: 1234 HILASGPQAAGASPHPHNAFVPPP-------------------PTLPAAVTGPDFPAGAH 1274
            HIL S P  +   P    A  PPP                   P+ P  +  P  P  A 
Sbjct: 2480 HILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISA- 2538

Query: 1275 RAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLT 1334
             +  ++     P  +    + +SP        + ++T  L   +PP  K  LP     L 
Sbjct: 2539 -SVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLS-LVPP--KDLLPVAVEILP 2594

Query: 1335 QSHPPQRLPKPLPLSPSFSSEVGQ---------REHQRGERDTAIPQPAKVPTTVDQGHI 1385
             S     L    P +PS + E G           +   G   T +P+  ++P  V + + 
Sbjct: 2595 VSEKNLSL---TPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESN- 2650

Query: 1386 PLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNAL----------NHDP 1435
             L   PS  S   LQ  L       T  + T +   +S P K   L          +   
Sbjct: 2651 GLELPPSAASDEPLQEPLEADR---TSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSA 2707

Query: 1436 TSPQWGPGP--------SGEQPMEGSHQGAPESP-------------------DSLQRNQ 1468
            TS   GP P        S +  + G   G P  P                     L R +
Sbjct: 2708 TSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRR 2767

Query: 1469 KELQGLLNQVQALEKEAASSVDVQALRRLF--EAVPQLGGAAPQAPAA 1514
            ++ +G  + +     E ++S    ++R +   E+ P +GG    AP++
Sbjct: 2768 RQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSS 2815


>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
          Length = 1090

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 69/281 (24%), Positives = 95/281 (33%), Gaps = 48/281 (17%)

Query: 1178 PRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILA 1237
            P P   GPG ++   R + G   + + G P +    + P                     
Sbjct: 466  PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA------------------TG 507

Query: 1238 SGPQAAGASPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASEP-LKDPLLHSHS 1296
            S PQ   +        VPP PT P A   P FPAG  + E  +  A  P L D      S
Sbjct: 508  STPQPGSSQQIQQRISVPPSPTYPPA-GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQS 566

Query: 1297 SPAGQRTPGGSQTKTPKLDPTMPPKK------------------KPQLP---PKPAHLTQ 1335
               G +T   S   +  L    PPK                   KP LP     P+ L  
Sbjct: 567  PRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626

Query: 1336 SHPPQRLPKPLPLSPSFSSEV-----GQREHQRGERDTAIPQPAKVPTTVDQGHIPLARC 1390
             H       P P  PS S+E      G      G    ++P+P          H PL R 
Sbjct: 627  LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL-RY 685

Query: 1391 PSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNAL 1431
             S     +L+  L+  APRP K +++ +  +    P +  L
Sbjct: 686  QSDADLEALRRKLA-NAPRPLKKRSSITEPEGPGGPNIQKL 725



 Score = 31.2 bits (69), Expect = 9.8
 Identities = 60/254 (23%), Positives = 91/254 (35%), Gaps = 50/254 (19%)

Query: 1280 IQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKK-PQLPPKPAHLTQSHP 1338
            +Q A    KDP   S      Q T          L PT  P  +  ++PP    + +  P
Sbjct: 403  VQVAGADWKDP---SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLP 459

Query: 1339 PQ--RLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQ 1396
            P     P P PL P  +S + +R      ++ ++P+P+                      
Sbjct: 460  PSYGTYPSPTPLGPGSTSSLERR------KEGSLPRPSA-------------------GL 494

Query: 1397 PSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGP-GPSGEQPMEGSHQ 1455
            PS Q        RPT   ATGS  Q     ++      P SP + P GP    P   +  
Sbjct: 495  PSRQ--------RPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGP----PAFPAGD 542

Query: 1456 GAPESPDSLQ-RNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGAAPQAPAA 1514
              PE P ++  R     +G   Q      +  +S  + ++  L +A P         PAA
Sbjct: 543  SKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSM-YLQQATPPKN----YQPAA 597

Query: 1515 HQKPEASVEQAFGE 1528
            H     SV+  +G+
Sbjct: 598  HSALNKSVKAVYGK 611


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
            sapiens]
          Length = 247

 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 54/208 (25%), Positives = 74/208 (35%), Gaps = 17/208 (8%)

Query: 1276 AEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKP------QLPPK 1329
            AE S +  S+  ++ L      P G+R  GG+Q + P   P  P    P      Q PP 
Sbjct: 16   AESSSEDVSQ--EESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPP 73

Query: 1330 PAHLTQSHPPQ-----RLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGH 1384
            P    +  PPQ     + P P P  P      G  + Q        P+    P   +Q H
Sbjct: 74   PPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPE-RPPPQGGNQSH 132

Query: 1385 IPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGP 1444
             P    P    +P  Q G  +  P P   +  G   Q  E  K  +    P  PQ  P  
Sbjct: 133  RP-PPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQ--EGNKSRSARSPPGKPQGPPQQ 189

Query: 1445 SGEQPMEGSHQGAPESPDSLQRNQKELQ 1472
             G +P      G P+ P     N ++ Q
Sbjct: 190  EGNKPQGPPPPGKPQGPPPAGGNPQQPQ 217



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 62/232 (26%), Positives = 73/232 (31%), Gaps = 46/232 (19%)

Query: 1104 RPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQRE 1163
            RP GG+ P+ P  P            G P G                  PP G   SQ  
Sbjct: 40   RPQGGNQPQRPPPPP-----------GKPQG-----------------PPPQGGNQSQGP 71

Query: 1164 PQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCP--GGLQA 1221
            P    +      Q     QG P     P R  P G  Q    PP     E  P  GG Q+
Sbjct: 72   PPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS 131

Query: 1222 AETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPP---TLPAAVTGPDFPAGAHRAED 1278
                       R     G Q+ G  PHP     PPP       +A + P  P G  + E 
Sbjct: 132  HRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEG 191

Query: 1279 SIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKP 1330
            +  Q   P           P G    GG+  +     P  PP  KPQ PP P
Sbjct: 192  NKPQGPPP--------PGKPQGPPPAGGNPQQ-----PQAPPAGKPQGPPPP 230


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 137/585 (23%), Positives = 191/585 (32%), Gaps = 131/585 (22%)

Query: 952  PSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAVPLAGEAAAP 1011
            P  V +S G    HP++     PPL+ +       A+  T    +A G+A  +    A P
Sbjct: 20   PRQVASSPG----HPSQ-----PPLEDNTP-----ATRTTKGAREAGGQAQAMELPEAQP 65

Query: 1012 AQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPG---APDLLAAMQSLRMATAEAQSL 1068
             Q ++ E +  S  GQ   +  GK  G+  TPPG     AP  LA         AE    
Sbjct: 66   RQARDGELKPPSLRGQAPSSTPGK-RGSPQTPPGRSPLQAPSRLAGR-------AEGSPP 117

Query: 1069 HQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALP 1128
             + +L        PT    P                     +P++ AA       E   P
Sbjct: 118  QRYILGIASSRTKPTLDETP--------------------ENPQLEAA----QLPEVDTP 153

Query: 1129 RGLPGGWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQA-PRPLQGGPGQ 1187
            +G PG    ++ G+         +  G  +  Q  P S       S  A PRP   GP Q
Sbjct: 154  QG-PGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQ 212

Query: 1188 STGPGREEPGGCTQM------AWGP------PG------KAMAEVCPGG----------- 1218
            S G    +PG   +       +W P      PG       A  E  P G           
Sbjct: 213  SRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVS 272

Query: 1219 -------LQAAETTLKTAPLGRHILASGP------QAAGASPHPHNAFVP--PPPTLPAA 1263
                   L  A T    A +  H   +GP      Q  GA P       P  P PT PA 
Sbjct: 273  FQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAP 332

Query: 1264 VTGPDF---PAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKT-PKLDPTMP 1319
               P +   P G +R  D     S P       +HS+P   R    S  K+  K+ P  P
Sbjct: 333  SPLPCYQGQPGGLNRHSDLSGALSSPGA-----AHSAP---RPFSDSLHKSLTKILPERP 384

Query: 1320 PKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAI----PQPAK 1375
            P  +  L       +   PP  LP+     P  +      +   G  DT +    P PA+
Sbjct: 385  PSAQDGLG------STRGPPSSLPQ--RHFPGQAYRASGVDTSPGPPDTELAAPGPPPAR 436

Query: 1376 VPTTVDQGHIPLARCP------------SGHSQPSLQHGLSTTAPRPTKNQATGSNAQSS 1423
            +P   D    P    P            +G   P  +  L  +AP P       +     
Sbjct: 437  LPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPH 496

Query: 1424 EPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQ 1468
                L+ L      P+W  G  G     G   G  E   +++ +Q
Sbjct: 497  GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQ 541



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 142/607 (23%), Positives = 194/607 (31%), Gaps = 125/607 (20%)

Query: 940  GLHSLRWEPPADPSPV-PASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAI 998
            G+ S R +P  D +P  P  E AQ          +P +D   G G    +GA   P    
Sbjct: 123  GIASSRTKPTLDETPENPQLEAAQ----------LPEVDTPQGPG----TGAPLRPGLPR 168

Query: 999  GKAVPLAGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDL--LAAMQ 1056
             +A P A E       Q       S +          S  AT  PP PG P     + +Q
Sbjct: 169  TEAQPAAEELGFHRCFQEPPSSFTSTNYT--------SPSATPRPPAPGPPQSRGTSPLQ 220

Query: 1057 SLRMATAEAQSLHQQVLNKHKQGP-----TPTATSNPIQDGLRKAGATQSNIRP------ 1105
                   +A              P      P A   PI  G R  G+ +           
Sbjct: 221  PGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPAL 280

Query: 1106 GGGSDPRIPA--APRKVSREEQALPRGLP-GGWVTIQDGIYTAHPVRTFDPPGGVQLSQR 1162
             G S    PA  A    +          P G W     G   A+P+ T   P  +   Q 
Sbjct: 281  HGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQG 340

Query: 1163 EPQSRHRETALSV---------QAPRPL-------------------QGGPGQSTGPG-- 1192
            +P   +R + LS           APRP                    Q G G + GP   
Sbjct: 341  QPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSS 400

Query: 1193 ---REEPGGCTQMAW-----GPPGKAMAEVCPGGLQAAETTLKTA-----PLGRHILASG 1239
               R  PG   + +      GPP   +A   P   +  +    TA     P G  + A+ 
Sbjct: 401  LPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATR 460

Query: 1240 PQAAGASPHP-------HNAFVPPPPTLPAAVTGPD---------FPAGAHRAEDSIQQA 1283
                   P P        +A +P P  LP A   P          FPAG    +   Q A
Sbjct: 461  SMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGA 520

Query: 1284 SEPLKDPLLHSHSSPAGQRTPGGSQ---TKTPKLDPTMPPK----KKPQLPPKPAHLTQS 1336
                          PA + + GGS    T     DP   P      +PQ+ P   H T S
Sbjct: 521  LGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP---HGTPS 577

Query: 1337 HPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPT--TVDQGHIPLARCPSGH 1394
             PP   P+ +  SPS S       +  G   +++   +  P   + ++  +P    PS  
Sbjct: 578  LPP---PRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAF 634

Query: 1395 SQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSH 1454
              P            PT  Q TGS   S EPP     ++ P   +  P P+     EG+ 
Sbjct: 635  FHP------------PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAF 682

Query: 1455 QGAPESP 1461
            Q   E+P
Sbjct: 683  QCLEETP 689



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 173/742 (23%), Positives = 247/742 (33%), Gaps = 120/742 (16%)

Query: 1026 GQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTAT 1085
            G +    L +    T +PP P         +SL +A   A S          +G TP   
Sbjct: 2013 GSRAAMSLQEEAEPTPSPPSPNR-------ESLALALTAAHS------RSGSEGRTPERA 2059

Query: 1086 SNPIQDGLRKAG-ATQSNIRPGGG----------SDPRIPAAPRKVSREEQAL-PRGLPG 1133
            S+P   GL K   AT  +  P  G          S   +P +   + RE+    P    G
Sbjct: 2060 SSP---GLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQG 2116

Query: 1134 GWVTIQDGIYTAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGG------PGQ 1187
            G      G   A P    DPPG  QL    P     E A  VQA             P  
Sbjct: 2117 GL----GGQLPASP-SCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSL 2171

Query: 1188 STGP--GREEPGGCTQMAWG---------PPGKAMAEVCP-GGLQAAETTLKTAPLGRHI 1235
            +T P   +E   GC     G         PPG   A  C   G    ++TL+     R  
Sbjct: 2172 TTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKE 2231

Query: 1236 L-------ASGPQAAGA---SPHPHNAFVPPPPTLPAAVTGPDFPAGAHRAEDSIQQASE 1285
                    A+ P  AGA   S       +   PT   A  G   P G           + 
Sbjct: 2232 KLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLP-GPDPQSRGAPPHTN 2290

Query: 1286 PLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPPQRLPKP 1345
            P + P  HS  SP+     G  + +     PT PP  +   P  PA L            
Sbjct: 2291 PDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACL------------ 2338

Query: 1346 LPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSLQHGLS- 1404
                              GE  T+  +P + P T + G     + P   + PS   GL  
Sbjct: 2339 -----------------EGEMGTSSKEP-EDPGTPETGRSGATKMPR-VTCPSTGLGLGR 2379

Query: 1405 TTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSL 1464
            TTAP      +T S+ QS  P      +H   +PQ    P G Q ++   +G  + P S 
Sbjct: 2380 TTAP-----SSTASDFQSDSPQSHRNASHQ--TPQ--GDPLGPQDLKQRSRGYKKKPAST 2430

Query: 1465 QRNQKELQGLLNQVQALEKEAASSVDVQALRR--LFEAVPQLGGAAPQAPAA--HQKPEA 1520
            +  Q + Q     V   E  AAS      L R    +  P  G  A  +PAA   Q+P  
Sbjct: 2431 ENGQWKGQAPHGPV-TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLE 2489

Query: 1521 SVEQAFGELTRVSTEVAQLKEQTLARLLDIEEAVH--KALSSMSSLQPEASARGHFQGPP 1578
             + Q      + S  V+  KE+      D         A  S   L+   S       PP
Sbjct: 2490 PLAQKCQPPRKKSHRVSG-KERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPP 2548

Query: 1579 KDHSAHKISV-TVSSSARPSGSGQ-EVGGQTAVKNQAKVECHTEAQSQVKIRNHTEARGH 1636
               + H++ V T +S  RP  + + E+  + A K + +       +  V   +H+E + +
Sbjct: 2549 SP-TEHEVDVKTPASKPRPDQAREDELHPKQAEKREGR---RWRREPTVDSPSHSEGKSN 2604

Query: 1637 TASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTFISIQSATRKPLETPSFKGNPDVSV 1696
                    RR            V+   R S  SP   S  ++   P    S +G P+   
Sbjct: 2605 KKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAAS---PSHCLSVEGGPEADG 2661

Query: 1697 KSTQLAQDIGQALLHQKGVQDK 1718
            +       +G  ++      D+
Sbjct: 2662 EQPPRLATLGPGVMEGAAETDQ 2683



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 95/440 (21%), Positives = 146/440 (33%), Gaps = 71/440 (16%)

Query: 1260 LPAAVTGPDFPAGAHRAEDSIQQASEPLKDPLLHSHSSPAGQRTPGGSQTKTPKLDPTMP 1319
            +P +  GP       R    I   SE     LLH  S  A   T G  +T    +DP   
Sbjct: 3451 MPGSAPGPGEDRPPPRGSSPI--LSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTH 3508

Query: 1320 PKKKPQLPPKPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTT 1379
            P +  +L   P++  +  PP   P P  L+              G  D A+    + P  
Sbjct: 3509 PIRGCEL---PSNHQECPPPSLSPFPAALAD-------------GRGDCALDGALERPEN 3552

Query: 1380 VDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQ 1439
                         G   P LQ  L   A  P +  A G +A+    P +       +  +
Sbjct: 3553 ---------EASPGSPGPLLQQALPLGASLP-RPGARGQDAEGKRAPLVF------SGKR 3596

Query: 1440 WGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAASS--VDVQALRRL 1497
              PG  G             +PD  Q +      LL +    EKE +SS  V     R  
Sbjct: 3597 RAPGARGRC-----------APDHFQEDH-----LLQK----EKEVSSSHMVSEGGPRGT 3636

Query: 1498 FEAVPQLGGAAPQAPAAHQKPEASVEQAFGELTRVSTEVAQLKEQTLARLLD--IEEAVH 1555
            F        A  Q+ +  +   ++  +A          V  L    LAR  +  ++ A  
Sbjct: 3637 FHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATP 3696

Query: 1556 KAL---SSMSSLQPEASARGHFQGPPKDHSAHKISVTVSSSARPSGSGQEVGGQTAVKNQ 1612
            KA    SS  S  P    +      P+  S    S T ++ A+PS   +    +      
Sbjct: 3697 KAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPE------ 3750

Query: 1613 AKVECHTEAQSQVKIRNHTEARGHTASTAPSTRRQETSREYLCPPRVLPSSRDSPSSPTF 1672
             ++    +A+S  K       +G   S  P  + + +++        +P    S S  +F
Sbjct: 3751 -RLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKR---KKGQVPGPARSESVGSF 3806

Query: 1673 ISIQSATRKPLETPSFKGNP 1692
                SA  KP  TP  +  P
Sbjct: 3807 GRAPSAPDKPPRTPRKQATP 3826



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 13/99 (13%)

Query: 1391 PSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPG--PSGEQ 1448
            PSG   PS  H L + A         G   +S  PP L A   DP +P+ G    P+  +
Sbjct: 873  PSGPRGPSSGHPLKSKA---------GVTPESKAPPPLPAATPDPQTPRPGDRGCPARGR 923

Query: 1449 PMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEKEAAS 1487
            P   S   AP   D+  + +++ +G   Q++   K+  S
Sbjct: 924  PKTRSLGLAPTEADAPSQGRQQRRG--KQLKLFRKDLDS 960



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 70/306 (22%), Positives = 101/306 (33%), Gaps = 35/306 (11%)

Query: 1179 RPLQGGPGQSTGPGREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHIL-- 1236
            RP  G   Q+ GP R    G      GP       V P       T  +T+   R  L  
Sbjct: 1134 RPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSLDF 1193

Query: 1237 ---ASGPQAAGASPHPHNAFVPPPPTLPAAVTG----------PDFPAGAHRAEDSIQQA 1283
               A  P+ A  S      F     + PAA  G          P+ P  + R +    + 
Sbjct: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPS-RHDTGTPKP 1252

Query: 1284 SEPLKDPLLHSHSSPAGQRT----PGGSQTKTPKLDPTMPPKKKPQLPPKPAHLTQSHPP 1339
            S  L +   H  S   G  +    PGG+Q      +   PP ++P     P     S   
Sbjct: 1253 SGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSH-NSKDPPARQPGEFLAPVANPSS--- 1308

Query: 1340 QRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQPAKVPTTVDQGHIPLARCPSGHSQPSL 1399
               PKP  LS   SS  G            +P   K P      H  L   P   +   L
Sbjct: 1309 TACPKPSVLSSKISS-FGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL 1367

Query: 1400 QHGLSTTAPRPTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPE 1459
            +       P+P+   A  +++        +A + +P  P+  PG +  +P      G   
Sbjct: 1368 EE----LHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEP------GRAA 1417

Query: 1460 SPDSLQ 1465
            SP +L+
Sbjct: 1418 SPPTLE 1423


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 161/666 (24%), Positives = 215/666 (32%), Gaps = 155/666 (23%)

Query: 943  SLRWEPPADPSPVPASEGAQSLHPTESIIHVPPLDPSMGMGHLRASGATPCPPQAIGKAV 1002
            S  W      S VP+  G+    P       PP DP +       S A   PP      +
Sbjct: 226  SYNWGAALRSSLVPSDLGSP---PAPHASSSPPSDPPL----FHCSDALTPPPLPPSNNL 278

Query: 1003 PL-AGEAAAPAQLQNTEKQEDSHSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMA 1061
            P   G A+ P     T              VLG   GA T   GPGAP  LA+  SL  A
Sbjct: 279  PAHPGPASQPPVSSATMHLP---------LVLGPLGGAPTVE-GPGAPPFLAS--SLLSA 326

Query: 1062 TAEAQSLHQQVLNKHKQGPTPTATSNPIQDGLRKAGATQSNIRP---------------- 1105
             A+AQ         H   P P+            + +  S++RP                
Sbjct: 327  AAKAQ---------HPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLE 377

Query: 1106 GGG------SDPRIPA-APRKVSREEQALP--------RGLPGGWVTIQDGIYTAHPVRT 1150
            G G      S PR PA  P+  S  E + P         GLP    +  DG +       
Sbjct: 378  GRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDA 437

Query: 1151 FDPPGGVQLSQREPQSRHRETALSVQAPRPLQGG-PGQSTGPGREEPGGCTQMAWGPPGK 1209
              PP     S   PQ RH           P+Q   PG ++G     PG     A  PP  
Sbjct: 438  HLPPPPTLSSGSPPQPRH-----------PIQPSLPGTTSGSLSSVPG-----APAPPAA 481

Query: 1210 AMAEVCPGGLQAAETTLKTAPLGRHILASGPQAAGASPHPHNAFVPPPPTLPAAVTGPDF 1269
            + A V P  +   ++  +   +G       P  AG    P      P P    A++G  F
Sbjct: 482  SKAPVVPSPV--LQSPSEGLGMGAGPACPLPPLAGGEAFPF-----PSPEQGLALSGAGF 534

Query: 1270 PA--GAHRAEDSIQQ------------------ASEPLKDPLLHSHSSPAGQRTPGGSQT 1309
            P   GA     S+ Q                    +P  +PLL     P     PG  + 
Sbjct: 535  PGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEG 594

Query: 1310 KTPKLDPTMPPKKKPQLPP---KPAHLTQSHPPQRLPKPLPLSPSFSSEVGQREHQRGE- 1365
             +  +   +PP     LPP    P++L  S  P      L L P+     G  E   G  
Sbjct: 595  PSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPL-----LALGPTAGDGEGSAEGAGGPS 649

Query: 1366 ----------RDTAIPQPAKVPTTVDQGHIPLARC---PSGHSQPSLQHGLSTTAPRPTK 1412
                           P  +  PT +      LA     PSG   P     LS   P P  
Sbjct: 650  GEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSG--TPPQPCVLSAPQPGPPT 707

Query: 1413 NQATGSN------------AQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPES 1460
            +  T +             + S  PP+L        SP  G    G+     S  GA  S
Sbjct: 708  SSVTTATTDPGASSLGKAPSNSGRPPQL-------LSPLLGASLLGDLSSLTSSPGALPS 760

Query: 1461 ----PDSLQRNQKELQGLLNQVQALEKEAASSVDVQALRRLFEAVPQLGGA---APQAPA 1513
                P  L   Q  LQ LL    A    + +S  +  L +  +  P+   A    P++PA
Sbjct: 761  LLQPPGPLLSGQLGLQ-LLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPA 819

Query: 1514 AHQKPE 1519
            +  +PE
Sbjct: 820  SALEPE 825



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 57/206 (27%), Positives = 73/206 (35%), Gaps = 52/206 (25%)

Query: 1294 SHSSPAGQRTPGGSQTKTPKLDPTMPPKKKP----------QLPPKPAHLTQSHP----- 1338
            SHSSP    +P    T +P      PP + P           LPP+P  ++Q+ P     
Sbjct: 122  SHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP 181

Query: 1339 ----PQRLPKPLPLSPSFSSEVGQREHQRGERDTAIPQP-------------------AK 1375
                P RL  P+P   S S     R   RG   +  P P                   + 
Sbjct: 182  GGLFPPRLADPVPSGGSSS----PRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSL 237

Query: 1376 VPTTVDQGHIPLARCPSGHSQPSLQH--GLSTTAPRPTKNQATGSNAQSSEPPKLNALNH 1433
            VP+ +     P A   S  S P L H     T  P P  N        +S+PP  +A  H
Sbjct: 238  VPSDLGSPPAPHA-SSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMH 296

Query: 1434 DPTSPQWGPGPSGEQP-MEGSHQGAP 1458
             P       GP G  P +EG   GAP
Sbjct: 297  LPLV----LGPLGGAPTVEG--PGAP 316


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 138/593 (23%), Positives = 199/593 (33%), Gaps = 89/593 (15%)

Query: 1024 HSGQKGMAVLGKSEGATTTPPGPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPT 1083
            HSG     +L      +  P   G P L     SL   +   QS         +  P   
Sbjct: 533  HSGAHSAHIL------SAAPIQVGQPALFQMPVSLAAGSLPTQS---------QPAPAGP 577

Query: 1084 ATSNPIQDGLRKAGATQSNIRPGGGSDPRIPAAPRKVSREEQALPRGLPGGWVTIQDGIY 1143
            A +  +Q       A      P G   P  PAA             G     +T+Q    
Sbjct: 578  AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT-----------GEAAPVLTVQPAPQ 626

Query: 1144 TAHPVRTFDPPGGVQLSQREPQSRHRETALSVQAPRPLQGGPGQSTGPGREEPGGCT--- 1200
                V T  P G  Q   ++P           QAP P    P Q+T P +  PG  +   
Sbjct: 627  APPAVSTPLPLGLQQPQAQQPP----------QAPTPQAAAPPQATTP-QPSPGLASSPE 675

Query: 1201 QMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRH---ILASGPQAAG------ASPHPHN 1251
            ++  G P  A     P  +   ++     P  R    + A GP  +       ++P P  
Sbjct: 676  KIVLGQPPSAT----PTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQ 731

Query: 1252 AFVPPPPTLPAAVTGPDFPAGAHRAEDSIQ-QASEPLKDPLLHSHSSPA-GQRTPGGSQT 1309
               P  P    A  GP  P        + Q  A+ PLK P     SSP+   + P G   
Sbjct: 732  DPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP--GPSSSPSLPHQAPLGDSP 789

Query: 1310 KTPKLDPTMPPKKKPQLP---PKPAHLTQSH--PPQRLPKPLPLSPSFSSEVGQREHQRG 1364
              P   PT PP + P  P    +P      H  PP + P  LP      +++G       
Sbjct: 790  HLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849

Query: 1365 ERDTA--IPQPAKVP-TTVDQGHIPLARCPSGHSQPSLQHG-------LSTTAPRPTKNQ 1414
               TA   PQP   P +   +G +P    P+ H  PS            S+  P PT + 
Sbjct: 850  PAPTAPGPPQPPLRPQSQPPEGPLP----PAPHLPPSSTSSAVASSSETSSRLPAPTPSD 905

Query: 1415 -------ATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRN 1467
                   + G +   + PP L+ L  +P +P   P P   Q +       P+    L+R 
Sbjct: 906  FQLQFPPSQGPHKSPTPPPTLH-LVPEPAAPP-PPPPRTFQMVTTPFPALPQPKALLERF 963

Query: 1468 QKELQGLLNQVQALEKEAA--SSVDVQALRRLFEAVPQLGGAAPQAPAAHQKPEASVEQA 1525
             +   G++ Q +A    AA  +S  +  L     +V   G A    P A     A    A
Sbjct: 964  HQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023

Query: 1526 FGELTRVSTEVAQLKEQTLARLLDIEEAVHKALSSMSSLQPEASARGHFQGPP 1578
               L  +     +     L   L++ +A        S LQ E+   G  + PP
Sbjct: 1024 ATGLPPLLPAENKAFASNLP-TLNVAKAASSGPGKPSGLQYESKLSG-LKKPP 1074



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 48/212 (22%), Positives = 72/212 (33%), Gaps = 22/212 (10%)

Query: 1319 PPKKKPQLPPKPAHL--TQSHPPQRLP--KPLPLSPSFSSEVGQREHQRGERDTAIPQ-- 1372
            PP + P  PP    +  T  HPP   P  KPL  +P       ++ ++        P+  
Sbjct: 1345 PPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGT 1404

Query: 1373 ---------PAKVPTTVDQGHIPLARCPSGHSQPSLQHGLSTTAPRPTKNQATGSNAQSS 1423
                     PA +P  VD+    L R  +       Q  L    P P  + A G+     
Sbjct: 1405 PAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW 1464

Query: 1424 EPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRNQKELQGLLNQVQALEK 1483
            E P L      P   +    P  +Q    S   +P+     +  Q  +  +LN  QA  +
Sbjct: 1465 EAPGL-----PPAKRRKSESPDVDQASFSS--DSPQDDTLTEHLQSAIDSILNLQQAPGR 1517

Query: 1484 EAASSVDVQALRRLFEAVPQLGGAAPQAPAAH 1515
              A S    A      + P L       P++H
Sbjct: 1518 TPAPSYPHAASAGTPASPPPLHRPEAYPPSSH 1549



 Score = 32.0 bits (71), Expect = 5.7
 Identities = 68/329 (20%), Positives = 110/329 (33%), Gaps = 46/329 (13%)

Query: 1038 GATTTPP-------------GPGAPDLLAAMQSLRMATAEAQSLHQQVLNKHKQGPTPTA 1084
            GA+T PP               G+P +  A  S  ++++ + S     L+  + GP P+ 
Sbjct: 1233 GASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSR 1292

Query: 1085 TSNPIQD-------GLR---KAGATQSNIRPGGGSDP-RIPAAPRKVSREEQALPRGLPG 1133
               PI+        GL+   K  A  S +      DP   P  P    +  +  PR  P 
Sbjct: 1293 NRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPP 1352

Query: 1134 GWVTIQDGIYTAHPVRTFDPPGGVQLSQREP--QSRHRETALSVQAPRPLQGGPGQSTGP 1191
               T Q      HP     PP      +R+P   + H       +  R   GGPG   G 
Sbjct: 1353 PPPTGQMNGTVDHP-----PPAA---PERKPLGTAPHCPRLPLRKTYRENVGGPGAPEG- 1403

Query: 1192 GREEPGGCTQMAWGPPGKAMAEVCPGGLQAAETTLKTAPLGRHILASGPQ----AAGASP 1247
                P G  +     P  A  +    GL      ++     R +    P+    AA  + 
Sbjct: 1404 ---TPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTG 1460

Query: 1248 HPHNAFVPPPPTLPAAVTGPDFPAGAHRA----EDSIQQASEPLKDPLLHSHSSPAGQRT 1303
             P       PP        PD    +  +    +D++ +  +   D +L+   +P     
Sbjct: 1461 DPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPA 1520

Query: 1304 PGGSQTKTPKLDPTMPPKKKPQLPPKPAH 1332
            P      +     + PP  +P+  P  +H
Sbjct: 1521 PSYPHAASAGTPASPPPLHRPEAYPPSSH 1549


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,951,599
Number of Sequences: 37866
Number of extensions: 5286310
Number of successful extensions: 27739
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 1129
Number of HSP's that attempted gapping in prelim test: 20007
Number of HSP's gapped (non-prelim): 6955
length of query: 1843
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1726
effective length of database: 13,817,196
effective search space: 23848480296
effective search space used: 23848480296
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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