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Search of human proteins with 40068485
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068485 von Willebrand factor A domain containing 1 isoform
1 [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068485 von Willebrand factor A domain containing 1 isoform ... 889 0.0
gi|40068487 von Willebrand factor A domain containing 1 isoform ... 476 e-134
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 148 1e-35
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 139 4e-33
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 134 2e-31
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 125 8e-29
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 118 9e-27
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 102 5e-22
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 102 5e-22
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 102 5e-22
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 100 5e-21
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 100 5e-21
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 94 2e-19
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 90 5e-18
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 88 2e-17
gi|11321565 matrilin 3 precursor [Homo sapiens] 86 5e-17
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 83 6e-16
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 83 6e-16
gi|205277471 cochlin precursor [Homo sapiens] 79 6e-15
gi|4758022 cochlin precursor [Homo sapiens] 79 6e-15
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 77 4e-14
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 77 4e-14
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ... 77 4e-14
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 75 9e-14
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 75 2e-13
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 74 2e-13
gi|21359974 vitrin [Homo sapiens] 74 3e-13
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 72 8e-13
gi|148886654 polydom [Homo sapiens] 65 2e-10
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 64 4e-10
>gi|40068485 von Willebrand factor A domain containing 1 isoform 1
[Homo sapiens]
Length = 445
Score = 889 bits (2296), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MLPWTALGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQL 60
MLPWTALGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQL
Sbjct: 1 MLPWTALGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQL 60
Query: 61 VAPLPLGTGALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYA 120
VAPLPLGTGALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYA
Sbjct: 61 VAPLPLGTGALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYA 120
Query: 121 KEQLFAEASGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSA 180
KEQLFAEASGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSA
Sbjct: 121 KEQLFAEASGARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSA 180
Query: 181 AASAPAEKHLHFVDVDDLHIIVQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADS 240
AASAPAEKHLHFVDVDDLHIIVQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADS
Sbjct: 181 AASAPAEKHLHFVDVDDLHIIVQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADS 240
Query: 241 GYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVR 300
GYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVR
Sbjct: 241 GYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVR 300
Query: 301 TRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAA 360
TRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAA
Sbjct: 301 TRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAA 360
Query: 361 ALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKAC 420
ALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKAC
Sbjct: 361 ALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKAC 420
Query: 421 TPDGPRPRPRPVPRAPTPGTASREP 445
TPDGPRPRPRPVPRAPTPGTASREP
Sbjct: 421 TPDGPRPRPRPVPRAPTPGTASREP 445
>gi|40068487 von Willebrand factor A domain containing 1 isoform 2
[Homo sapiens]
Length = 233
Score = 476 bits (1224), Expect = e-134
Identities = 233/233 (100%), Positives = 233/233 (100%)
Query: 213 MRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAG 272
MRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAG
Sbjct: 1 MRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAG 60
Query: 273 LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE 332
LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE
Sbjct: 61 LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE 120
Query: 333 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQG 392
AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQG
Sbjct: 121 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQG 180
Query: 393 LAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGTASREP 445
LAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGTASREP
Sbjct: 181 LAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGTASREP 233
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 148 bits (373), Expect = 1e-35
Identities = 122/425 (28%), Positives = 191/425 (44%), Gaps = 47/425 (11%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
+ D++FL+D S S+ F +VR F+ LV + ++ SLV P+TEF +
Sbjct: 438 KADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKF 497
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
+ E +A+ R G T+TG A+ Y +E++F + G+R VPKV++ +TDG SSD
Sbjct: 498 TKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAF 557
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI- 209
P +L++ V +F V EL A AS PAE H+ V D D I EL SI
Sbjct: 558 RDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSIC 617
Query: 210 ------LDAMR------PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
L A++ P+ L +E+TS GF+ W P Y++ +
Sbjct: 618 LRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTV 677
Query: 258 RQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGA 317
+ P ++T + + L P+T Y V + E G S P A
Sbjct: 678 VE--PASSTSVVLSSLKPETLYLVNVTAEYE-------------------DGFSIPL--A 714
Query: 318 GPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQ 377
G T+ + P + ++ S +++W A G L Y + + P+ GGE++
Sbjct: 715 GEETTE------EVKGAPRNLKVTDETTDSFKITWTQAPG--RVLRYRIIYRPVAGGESR 766
Query: 378 RVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPT 437
V P + TL+ L P T Y V+V + SG + L+ A T + R PR + R
Sbjct: 767 EVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEE-VRGNPRDL-RVSD 824
Query: 438 PGTAS 442
P T++
Sbjct: 825 PTTST 829
Score = 122 bits (307), Expect = 5e-28
Identities = 109/407 (26%), Positives = 173/407 (42%), Gaps = 47/407 (11%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++ L+D S S+ F VR F+ ++V +G ++ +L P TE+ H
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
++ AV + G+T TG+AL + ++Q F +G RP K+ V +TDG S D V
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEA 1318
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSILDA 212
P ++LKD GV +F + + +EL A+ P + H + V D + L IV +L ++ ++
Sbjct: 1319 PSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNS 1378
Query: 213 MR-------PQQLHATEITSSGFRLAW-PPLLTADSGYYVLELVPSAQPGAARRQQLPGN 264
++ P L +E T FR++W PP + D Y +E P G + +
Sbjct: 1379 VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDR--YKVEYYP-VSGGKRQEFYVSRM 1435
Query: 265 ATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQL 324
T + L P+T+Y V + P G E
Sbjct: 1436 ETSTVLKDLKPETEYVVNVYSVVEDEYSEP---------------LKGTEK--------- 1471
Query: 325 AALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR-VEVPA 383
LP P + + I P ++ V W P G A GY + + P++ E R EV
Sbjct: 1472 -TLPVPVVS----LNIYDVGPTTMHVQWQPVGG---ATGYILSYKPVKDTEPTRPKEVRL 1523
Query: 384 GRNCTTLQ--GLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPR 428
G +Q L P T Y VTV A ++ + T PRP+
Sbjct: 1524 GPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQ 1570
Score = 112 bits (279), Expect = 9e-25
Identities = 82/286 (28%), Positives = 129/286 (45%), Gaps = 17/286 (5%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+FL+D S SV F + +F+ LV+ +G R +V S TEF Q+
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ A++ + G+T TG A+ Y + F E++GAR G PKV + +TDG S D V
Sbjct: 200 RDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEI 259
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLH-------FVDVDDLHII----- 201
P +EL+++GV VF + + EL AS P+ H+ VD+ + I
Sbjct: 260 PARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSG 319
Query: 202 VQELRGSILDAMR----PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
V E G ++ P L A E++S +L W P + +GY V+ L P
Sbjct: 320 VDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVI-LTPMTAGSRQH 378
Query: 258 RQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRP 303
+ T L DT+Y +++ + P + +T+P
Sbjct: 379 ALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
Score = 90.9 bits (224), Expect = 2e-18
Identities = 57/174 (32%), Positives = 88/174 (50%), Gaps = 5/174 (2%)
Query: 26 PPA----SAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLP-LGTGALRASLVHVGS 80
PPA + D++FL D+S S+ F++V +F+ V + ++ S V
Sbjct: 2311 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 2370
Query: 81 RPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLV 140
+EF ++ A A++ R G+T TG AL + KE++ SG R VPKVLV
Sbjct: 2371 EVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLV 2430
Query: 141 WVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD 194
VTDG S D V ++ G +VF+V ++ EL+ AS P+E+H+ VD
Sbjct: 2431 VVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVD 2484
Score = 68.6 bits (166), Expect = 1e-11
Identities = 58/209 (27%), Positives = 85/209 (40%), Gaps = 35/209 (16%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLD 274
P+ L T+ T+ F++ W Y ++ + G +R P N L
Sbjct: 726 PRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAG--GESREVTTPPNQRRRTLENLI 783
Query: 275 PDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE-- 332
PDT Y+V+++PE +GPG T L A EE
Sbjct: 784 PDTKYEVSVIPEY-----------------FSGPG------------TPLTGNAATEEVR 814
Query: 333 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQG 392
P + +S ++++SW+ A G Y V + P+ GGE Q V V T LQG
Sbjct: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQ--YLVTYTPVAGGETQEVTVRGDTTNTVLQG 872
Query: 393 LAPGTAYLVTVTAAFRSGRESALSAKACT 421
L GT Y ++VTA + SG AL + T
Sbjct: 873 LKEGTQYALSVTALYASGAGDALFGEGTT 901
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/210 (24%), Positives = 83/210 (39%), Gaps = 29/210 (13%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQ--LPGNATDWIWAG 272
P L TE+TS GFR W +D Y + P G++ + + L G+ ++
Sbjct: 1658 PTNLKITEVTSEGFRGTWDHG-ASDVSLYRITWAPF---GSSDKMETILNGDENTLVFEN 1713
Query: 273 LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE 332
L+P+T Y+V++ P S + G T +
Sbjct: 1714 LNPNTIYEVSITA--------------------IYPDESESDDLIGSERTLPILTTQAPK 1753
Query: 333 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRG-GEAQRVEVPAGRNCTTLQ 391
+GP + + +A SL V W PA G Y + + P G G Q + +N LQ
Sbjct: 1754 SGPRNLQVYNATSNSLTVKWDPASGRVQK--YRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811
Query: 392 GLAPGTAYLVTVTAAFRSGRESALSAKACT 421
L P T Y +TV++ + G ++ + T
Sbjct: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKT 1841
Score = 47.8 bits (112), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 34/189 (17%)
Query: 243 YVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTR 302
Y L P+A G +PGN I L PDT Y V +VP V T
Sbjct: 1874 YKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVP-------------VYTE 1919
Query: 303 PGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAAL 362
G G ++G T + L + + + P SL V W PA G L
Sbjct: 1920 ----GDGGRTSDTGR----TLMRGLA-------RNVQVYNPTPNSLDVRWDPAPGPV--L 1962
Query: 363 GYHVQFGPLRGGE-AQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACT 421
Y V + P+ G ++ + VP L+ L P T Y V + A + G + A+ T
Sbjct: 1963 QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 2022
Query: 422 PDGPRPRPR 430
PR PR
Sbjct: 2023 L--PRSGPR 2029
Score = 46.6 bits (109), Expect = 5e-05
Identities = 54/235 (22%), Positives = 82/235 (34%), Gaps = 37/235 (15%)
Query: 207 GSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVL-ELVPSAQPGAARRQQLPGNA 265
G + + PQ +H ++ + FR++W P + GY ++ + V S +P A G
Sbjct: 2111 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEA----FVGEM 2166
Query: 266 TDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLA 325
T + L+P T YDV + + + G S P + G
Sbjct: 2167 TSYTLHNLNPSTTYDVNVYAQYD-------------------SGLSVPLTDQGTTLYLNV 2207
Query: 326 ALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGR 385
+ G + V W+P AA Y ++ P G Q + V
Sbjct: 2208 TDLKTYQIGWDTFC----------VKWSP---HRAATSYRLKLSPADGTRGQEITVRGSE 2254
Query: 386 NCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGT 440
GL+P T Y VTV + +S K T P P P P P T
Sbjct: 2255 TSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPT 2309
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/196 (22%), Positives = 65/196 (33%), Gaps = 31/196 (15%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLD 274
P+ L TS+ + W P + Y + PS G + + G + L
Sbjct: 1756 PRNLQVYNATSNSLTVKWDPA-SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLK 1814
Query: 275 PDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAG 334
PDT Y + V L P G G +G G
Sbjct: 1815 PDTPYTIT------VSSLYPD-------------GEGGRMTGRGKTKPLNTV-------- 1847
Query: 335 PERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLA 394
+ + +L V W A G+ Y + + P GG + V +P N L+ L
Sbjct: 1848 -RNLRVYDPSTSTLNVRWDHAEGNPRQ--YKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 1904
Query: 395 PGTAYLVTVTAAFRSG 410
P T+Y VTV + G
Sbjct: 1905 PDTSYTVTVVPVYTEG 1920
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 6/104 (5%)
Query: 319 PAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR 378
P+P Q LP +GP + + SL V+W A G Y + + P G
Sbjct: 2015 PSPAQGRTLP---RSGPRNLRVFGETTNSLSVAWDHADGPVQQ--YRIIYSPTVGDPIDE 2069
Query: 379 -VEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACT 421
VP RN LQ L P T Y +TV A + G L+ T
Sbjct: 2070 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 2113
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/198 (23%), Positives = 73/198 (36%), Gaps = 35/198 (17%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVL--ELVPSAQPGAARRQQLPGNATDWIWAG 272
PQ L +IT + W GY V L G + LP +A +
Sbjct: 908 PQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTG---EKNLPEDAIHTMIEN 964
Query: 273 LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE 332
L P+T Y +++ + +G G E G A T+L+
Sbjct: 965 LQPETKYRISVFATYS-----------------SGEG----EPLTGDATTELSQ------ 997
Query: 333 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQG 392
+ + + ++RV+W PA G + Y V + P G+ +VP T L+
Sbjct: 998 -DSKTLKVDEETENTMRVTWKPAPGKV--VNYRVVYRPHGRGKQMVAKVPPTVTSTVLKR 1054
Query: 393 LAPGTAYLVTVTAAFRSG 410
L P T Y +TV ++ G
Sbjct: 1055 LQPQTTYDITVLPIYKMG 1072
Score = 35.4 bits (80), Expect = 0.11
Identities = 36/122 (29%), Positives = 48/122 (39%), Gaps = 25/122 (20%)
Query: 228 FRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLP--GNATDWIWAGLDPDTDYDVALVP 285
F + W P A S Y L+L P+ R Q++ G+ T + GL PDTDY V +
Sbjct: 2220 FCVKWSPHRAATS--YRLKLSPA---DGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFV 2274
Query: 286 ESNVRLLRPQILRVRTRPGEAGPGASGPESGA---GPAPTQLAALPAPEEAGPERIVISH 342
++ P GPG S E APT+ P P P R V
Sbjct: 2275 QT---------------PNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKG 2319
Query: 343 AR 344
A+
Sbjct: 2320 AK 2321
Score = 34.3 bits (77), Expect = 0.23
Identities = 44/219 (20%), Positives = 70/219 (31%), Gaps = 36/219 (16%)
Query: 198 LHIIVQE---LRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPG 254
LH + E +R L RPQ L ++T S + W P+ Y V P
Sbjct: 1549 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEED-- 1606
Query: 255 AARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPE 314
+ ++ + T L T Y V++ A E
Sbjct: 1607 -VKEVEVDRSETSTSLKDLFSQTLYTVSV-------------------------SAVHDE 1640
Query: 315 SGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGG 374
+ P Q P P P + I+ R +W G++ Y + + P
Sbjct: 1641 GESPPVTAQETTRPVP---APTNLKITEVTSEGFRGTWDH--GASDVSLYRITWAPFGSS 1695
Query: 375 EAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRES 413
+ + N + L P T Y V++TA + ES
Sbjct: 1696 DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 15/119 (12%)
Query: 319 PAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR 378
P + LP P P+ + + ++ V W P G Y V++ + +
Sbjct: 1556 PVTVREVTLPLPR---PQDLKLRDVTHSTMNVFWEPVPGKVRK--YIVRYKTPEE-DVKE 1609
Query: 379 VEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPT 437
VEV T+L+ L T Y V+V+A G ++A+ T RPVP APT
Sbjct: 1610 VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT--------RPVP-APT 1659
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Query: 347 SLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTA 405
++ +SWA + +GY + P G + + A T L L P T Y+VT+T+
Sbjct: 40 TVHMSWAKPVDPI--VGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITS 96
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 139 bits (351), Expect = 4e-33
Identities = 124/424 (29%), Positives = 180/424 (42%), Gaps = 57/424 (13%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
PP A D++FL+D S S+ H F +V++F+ ++AP +G ++ L TE
Sbjct: 174 PPVPA---DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTE 230
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDG 145
+ S+ E AVR + G+T TGLAL + Q A+G RP KV++ VTDG
Sbjct: 231 WDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDG 290
Query: 146 GSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLH----FVDVDDL--- 198
S D V + LKDLGV VF V + EL AS P + +H F+ + L
Sbjct: 291 KSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGL 350
Query: 199 --HIIVQELRGS----------ILDAM-RPQQLHATEITSSGFRLAWPPLLTADSGYYVL 245
+I Q L+G LD + P L +++TSS RL+W P Y +
Sbjct: 351 LSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI- 409
Query: 246 ELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGE 305
+ +++ G R + G A L T+Y V++ P G
Sbjct: 410 -VWRASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFP---------------IYEGG 453
Query: 306 AGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYH 365
G G G + A P P + ++ PR++ ++W P SA A Y
Sbjct: 454 VGEGLRGLVTTAPLPP-------------PRALTLAAVTPRTVHLTWQP---SAGATHYL 497
Query: 366 VQFGPLR-GGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDG 424
V+ P GE + EV GR L GL PG Y V+V + A +A TP
Sbjct: 498 VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557
Query: 425 PRPR 428
PR
Sbjct: 558 APPR 561
Score = 76.3 bits (186), Expect = 5e-14
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 41/226 (18%)
Query: 212 AMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELV--PSAQPGAARRQQLPGNATDWI 269
A P QL TE+ +LAW + A SG V ++ P + G A +PGN +
Sbjct: 647 APSPSQLSMTELPGDAVQLAW--VAAAPSGVLVYQITWTPLGE-GKAHEISVPGNLGTAV 703
Query: 270 WAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPA 329
GL T+YDV ++ GA P L P+
Sbjct: 704 LPGLGRHTEYDVTILAYYR--------------------------DGARSDPVSLRYTPS 737
Query: 330 P-EEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRG-GEAQRVEVPAGRNC 387
+ P + ++ P SL+VSW P LG L Y + + P G G + V VP R+
Sbjct: 738 TVSRSPPSNLALASETPDSLQVSWTPPLGRV--LHYWLTYAPASGLGPEKSVSVPGARSH 795
Query: 388 TTLQGLAPGTAYLVTVTAAFRSGRESALSA------KACTPDGPRP 427
TL L T Y V V+A + +GR A+SA A PDG P
Sbjct: 796 VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLP 841
Score = 52.0 bits (123), Expect = 1e-06
Identities = 65/305 (21%), Positives = 106/305 (34%), Gaps = 83/305 (27%)
Query: 205 LRGSILDAMRP--QQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLP 262
LRG + A P + L +T L W P +A + +Y++ P++ G +++
Sbjct: 458 LRGLVTTAPLPPPRALTLAAVTPRTVHLTWQP--SAGATHYLVRCSPASPKGEEEEREVQ 515
Query: 263 GNATDWIWAGLDPDTDYDVALV----PESN------------------------------ 288
+ + GL+P DY+V++ PE +
Sbjct: 516 VGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARV 575
Query: 289 --------VRLLRPQILRVR-------TRPGEAGPGASGPESGA-------------GPA 320
VRL+R + PG A GP S + G +
Sbjct: 576 FWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGS 635
Query: 321 PTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVE 380
T + + P ++ ++ +++++W A S L Y + + PL G+A +
Sbjct: 636 STLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGV-LVYQITWTPLGEGKAHEIS 694
Query: 381 VPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGT 440
VP L GL T Y VT+ A +R G R PV TP T
Sbjct: 695 VPGNLGTAVLPGLGRHTEYDVTILAYYRDG----------------ARSDPVSLRYTPST 738
Query: 441 ASREP 445
SR P
Sbjct: 739 VSRSP 743
Score = 34.3 bits (77), Expect = 0.23
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 348 LRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAF 407
L++ W + GS LGY VQ P+ G Q V + T+ GL+P Y + +
Sbjct: 42 LQMKWRESEGSG--LGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99
Query: 408 RSGR 411
SGR
Sbjct: 100 GSGR 103
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 134 bits (336), Expect = 2e-31
Identities = 129/427 (30%), Positives = 172/427 (40%), Gaps = 58/427 (13%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGA--LRASLVHVGSRPYTEFPFGQH 91
D++FLLD S+S+ F VR F+ LV P A +R + V P TEF
Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
SG A+R + + G+T TG A+++ + +F ARPGVPKV + +TDG S D V
Sbjct: 98 GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCILITDGKSQDLV 156
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHII---------- 201
Q LK GV +F V + EL AS P F V+D I+
Sbjct: 157 DTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFF--VNDFSILRTLLPLVSRR 214
Query: 202 -------VQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYV--LELVPSAQ 252
V R P+ L +E +S R+ W +GY V L Q
Sbjct: 215 VCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQ 274
Query: 253 PGAARRQQ--LPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGA 310
P + RQ+ +P T GL P T+Y V + I GEA G
Sbjct: 275 PLPSERQEVNVPAGETSVRLRGLRPLTEYQVTV------------IALYANSIGEAVSGT 322
Query: 311 SGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGP 370
+ + AL PE + I + SL V+W G A GY V +
Sbjct: 323 A-----------RTTALEGPE------LTIQNTTAHSLLVAWRSVPG---ATGYRVTWRV 362
Query: 371 LRGGEAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPR 430
L GG Q+ E+ G+ L+ L PGT Y VTV+ F A S A T R
Sbjct: 363 LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLR 422
Query: 431 PVPRAPT 437
PV PT
Sbjct: 423 PVILGPT 429
Score = 56.2 bits (134), Expect = 6e-08
Identities = 56/211 (26%), Positives = 83/211 (39%), Gaps = 35/211 (16%)
Query: 218 LHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDT 277
+H T+ +SS + W + A +GY V + G + Q + G AT GL+PDT
Sbjct: 692 VHVTQASSSSVTITWTRVPGA-TGYRVSW---HSAHGPEKSQLVSGEATVAELDGLEPDT 747
Query: 278 DYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGP-E 336
+Y V VR G GP P + APE G
Sbjct: 748 EYTV----------------HVRAHVA----GVDGP-------PASVVVRTAPEPVGRVS 780
Query: 337 RIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPG 396
R+ I +A LR++W G+ A Y + +G GG + +P + ++GL G
Sbjct: 781 RLQILNASSDVLRITWVGVTGATA---YRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGG 837
Query: 397 TAYLVTVTAAFRSGRESALSAKACTPDGPRP 427
+Y V VTA + +S TP P
Sbjct: 838 VSYSVRVTALVGDREGTPVSIVVTTPPEAPP 868
Score = 47.0 bits (110), Expect = 3e-05
Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 36/200 (18%)
Query: 218 LHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDT 277
L ATE+ R++W P+ G ++ + G R LPG+ T + +
Sbjct: 514 LQATELPGQRVRVSWSPV----PGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGL 569
Query: 278 DYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPER 337
Y V + R +L VR P P + L R
Sbjct: 570 SYTVRVSARVGPREGSASVLTVRREP---------------ETPLAVPGL---------R 605
Query: 338 IVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLAPGT 397
+V+S A +RV+W P G++ G+ + + G E+ + +P T + GL PGT
Sbjct: 606 VVVSDAT--RVRVAWGPVPGAS---GFRISWSTGSGPESSQT-LPPDSTATDITGLQPGT 659
Query: 398 AYLVTVTAAFRSGRESALSA 417
Y V V+ GRE +A
Sbjct: 660 TYQVAVSVL--RGREEGPAA 677
Score = 45.8 bits (107), Expect = 8e-05
Identities = 44/155 (28%), Positives = 68/155 (43%), Gaps = 10/155 (6%)
Query: 24 RGPPASA------PRG--DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASL 75
RGP AS PRG D++FL ++ +H + R ++A PLG A++ L
Sbjct: 1036 RGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGL 1095
Query: 76 VHVGSRPYTEFPF-GQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFA-EASGARP 133
+ RP FP G H G Q + G A+V A + A +A G R
Sbjct: 1096 LSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQ 1155
Query: 134 GVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIV 168
VP V+V + D + P++E + G+ V ++
Sbjct: 1156 HVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVML 1190
Score = 34.3 bits (77), Expect = 0.23
Identities = 55/221 (24%), Positives = 80/221 (36%), Gaps = 34/221 (15%)
Query: 211 DAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIW 270
DA Q L + + L+W L ++ Y LE ++ LP + T +
Sbjct: 414 DASVEQTLRPVILGPTSILLSWN--LVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQL 471
Query: 271 AGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAP 330
GL P T+Y RL +L A +GPE P T L A P
Sbjct: 472 DGLQPGTEY----------RLTLYTLLEGHEVATPATVVPTGPELPVSPV-TDLQATELP 520
Query: 331 EEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTL 390
+ +RVSW+P G A Y + +G E V +P + L
Sbjct: 521 GQ--------------RVRVSWSPVPG---ATQYRIIVRSTQGVERTLV-LPGSQTAFDL 562
Query: 391 QGLAPGTAYLVTVTAAF--RSGRESALSAKACTPDGPRPRP 429
+ G +Y V V+A R G S L+ + P+ P P
Sbjct: 563 DDVQAGLSYTVRVSARVGPREGSASVLTVRR-EPETPLAVP 602
Score = 32.7 bits (73), Expect = 0.68
Identities = 22/72 (30%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 217 QLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGA---ARRQQLPGNATDWIWAGL 273
+L + + LAW P+ A S Y+L P PG Q LPG ++ GL
Sbjct: 961 ELRVVDTSIDSVTLAWTPVSRASS--YILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGL 1018
Query: 274 DPDTDYDVALVP 285
+P Y +L P
Sbjct: 1019 EPGVSYIFSLTP 1030
Score = 28.9 bits (63), Expect = 9.9
Identities = 24/72 (33%), Positives = 29/72 (40%), Gaps = 2/72 (2%)
Query: 300 RTRPGEAG-PGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGS 358
R PG AG PGA GPE GP Q P + + A P+ + PA G
Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPA-GP 1564
Query: 359 AAALGYHVQFGP 370
A G + GP
Sbjct: 1565 RGATGVQGERGP 1576
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 125 bits (314), Expect = 8e-29
Identities = 115/431 (26%), Positives = 181/431 (41%), Gaps = 47/431 (10%)
Query: 10 ALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTG 69
AL L L+ AE + D++ L+D S S+ F VR F+ ++V +G
Sbjct: 11 ALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPK 70
Query: 70 ALRASLVHVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEAS 129
++ +L P TE+ H ++ AV + G+T TG+AL + ++Q F +
Sbjct: 71 RVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQA 130
Query: 130 GARPGVPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKH 189
G RP K+ V +TDG S D V P ++LKD GV +F + + +EL A+ P + H
Sbjct: 131 GMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTH 190
Query: 190 LHFV-DVDDLHIIVQELRGSILDAMR-------PQQLHATEITSSGFRLAW-PPLLTADS 240
+ V D + L IV +L ++ ++++ P L +E T FR++W PP + D
Sbjct: 191 AYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDR 250
Query: 241 GYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVR 300
Y +E P G + + T + L P+T+Y V + P
Sbjct: 251 --YKVEYYP-VSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEP------ 301
Query: 301 TRPGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAA 360
G E LP P + + I P ++ V W P G
Sbjct: 302 ---------LKGTEK----------TLPVPVVS----LNIYDVGPTTMHVQWQPVGG--- 335
Query: 361 ALGYHVQFGPLRGGEAQR-VEVPAGRNCTTLQ--GLAPGTAYLVTVTAAFRSGRESALSA 417
A GY + + P++ E R EV G +Q L P T Y VTV A ++
Sbjct: 336 ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTV 395
Query: 418 KACTPDGPRPR 428
+ T PRP+
Sbjct: 396 REVTLPLPRPQ 406
Score = 90.9 bits (224), Expect = 2e-18
Identities = 57/174 (32%), Positives = 88/174 (50%), Gaps = 5/174 (2%)
Query: 26 PPA----SAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLP-LGTGALRASLVHVGS 80
PPA + D++FL D+S S+ F++V +F+ V + ++ S V
Sbjct: 1147 PPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSD 1206
Query: 81 RPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLV 140
+EF ++ A A++ R G+T TG AL + KE++ SG R VPKVLV
Sbjct: 1207 EVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLV 1266
Query: 141 WVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD 194
VTDG S D V ++ G +VF+V ++ EL+ AS P+E+H+ VD
Sbjct: 1267 VVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVD 1320
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/210 (24%), Positives = 83/210 (39%), Gaps = 29/210 (13%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQ--LPGNATDWIWAG 272
P L TE+TS GFR W +D Y + P G++ + + L G+ ++
Sbjct: 494 PTNLKITEVTSEGFRGTWDHG-ASDVSLYRITWAPF---GSSDKMETILNGDENTLVFEN 549
Query: 273 LDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEE 332
L+P+T Y+V++ P S + G T +
Sbjct: 550 LNPNTIYEVSITA--------------------IYPDESESDDLIGSERTLPILTTQAPK 589
Query: 333 AGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRG-GEAQRVEVPAGRNCTTLQ 391
+GP + + +A SL V W PA G Y + + P G G Q + +N LQ
Sbjct: 590 SGPRNLQVYNATSNSLTVKWDPASGRVQK--YRITYQPSTGEGNEQTTTIGGRQNSVVLQ 647
Query: 392 GLAPGTAYLVTVTAAFRSGRESALSAKACT 421
L P T Y +TV++ + G ++ + T
Sbjct: 648 KLKPDTPYTITVSSLYPDGEGGRMTGRGKT 677
Score = 47.8 bits (112), Expect = 2e-05
Identities = 53/189 (28%), Positives = 72/189 (38%), Gaps = 34/189 (17%)
Query: 243 YVLELVPSAQPGAARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTR 302
Y L P+A G +PGN I L PDT Y V +VP V T
Sbjct: 710 YKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVP-------------VYTE 755
Query: 303 PGEAGPGASGPESGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAAL 362
G G ++G T + L + + + P SL V W PA G L
Sbjct: 756 ----GDGGRTSDTGR----TLMRGLA-------RNVQVYNPTPNSLDVRWDPAPGPV--L 798
Query: 363 GYHVQFGPLRGGE-AQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACT 421
Y V + P+ G ++ + VP L+ L P T Y V + A + G + A+ T
Sbjct: 799 QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 858
Query: 422 PDGPRPRPR 430
PR PR
Sbjct: 859 L--PRSGPR 865
Score = 46.6 bits (109), Expect = 5e-05
Identities = 54/235 (22%), Positives = 82/235 (34%), Gaps = 37/235 (15%)
Query: 207 GSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVL-ELVPSAQPGAARRQQLPGNA 265
G + + PQ +H ++ + FR++W P + GY ++ + V S +P A G
Sbjct: 947 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEA----FVGEM 1002
Query: 266 TDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLA 325
T + L+P T YDV + + + G S P + G
Sbjct: 1003 TSYTLHNLNPSTTYDVNVYAQYD-------------------SGLSVPLTDQGTTLYLNV 1043
Query: 326 ALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGR 385
+ G + V W+P AA Y ++ P G Q + V
Sbjct: 1044 TDLKTYQIGWDTFC----------VKWSP---HRAATSYRLKLSPADGTRGQEITVRGSE 1090
Query: 386 NCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPTPGT 440
GL+P T Y VTV + +S K T P P P P P T
Sbjct: 1091 TSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPT 1145
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/196 (22%), Positives = 65/196 (33%), Gaps = 31/196 (15%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLD 274
P+ L TS+ + W P + Y + PS G + + G + L
Sbjct: 592 PRNLQVYNATSNSLTVKWDPA-SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLK 650
Query: 275 PDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAG 334
PDT Y + V L P G G +G G
Sbjct: 651 PDTPYTIT------VSSLYPD-------------GEGGRMTGRGKTKPLNTV-------- 683
Query: 335 PERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTTLQGLA 394
+ + +L V W A G+ Y + + P GG + V +P N L+ L
Sbjct: 684 -RNLRVYDPSTSTLNVRWDHAEGNPRQ--YKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 740
Query: 395 PGTAYLVTVTAAFRSG 410
P T+Y VTV + G
Sbjct: 741 PDTSYTVTVVPVYTEG 756
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 6/104 (5%)
Query: 319 PAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR 378
P+P Q LP +GP + + SL V+W A G Y + + P G
Sbjct: 851 PSPAQGRTLP---RSGPRNLRVFGETTNSLSVAWDHADGPVQQ--YRIIYSPTVGDPIDE 905
Query: 379 -VEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACT 421
VP RN LQ L P T Y +TV A + G L+ T
Sbjct: 906 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 949
Score = 35.4 bits (80), Expect = 0.11
Identities = 36/122 (29%), Positives = 48/122 (39%), Gaps = 25/122 (20%)
Query: 228 FRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLP--GNATDWIWAGLDPDTDYDVALVP 285
F + W P A S Y L+L P+ R Q++ G+ T + GL PDTDY V +
Sbjct: 1056 FCVKWSPHRAATS--YRLKLSPA---DGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFV 1110
Query: 286 ESNVRLLRPQILRVRTRPGEAGPGASGPESGA---GPAPTQLAALPAPEEAGPERIVISH 342
++ P GPG S E APT+ P P P R V
Sbjct: 1111 QT---------------PNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKG 1155
Query: 343 AR 344
A+
Sbjct: 1156 AK 1157
Score = 34.3 bits (77), Expect = 0.23
Identities = 44/219 (20%), Positives = 70/219 (31%), Gaps = 36/219 (16%)
Query: 198 LHIIVQE---LRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPG 254
LH + E +R L RPQ L ++T S + W P+ Y V P
Sbjct: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEED-- 442
Query: 255 AARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPE 314
+ ++ + T L T Y V++ A E
Sbjct: 443 -VKEVEVDRSETSTSLKDLFSQTLYTVSV-------------------------SAVHDE 476
Query: 315 SGAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGG 374
+ P Q P P P + I+ R +W G++ Y + + P
Sbjct: 477 GESPPVTAQETTRPVP---APTNLKITEVTSEGFRGTWDH--GASDVSLYRITWAPFGSS 531
Query: 375 EAQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRES 413
+ + N + L P T Y V++TA + ES
Sbjct: 532 DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 15/119 (12%)
Query: 319 PAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR 378
P + LP P P+ + + ++ V W P G Y V++ + +
Sbjct: 392 PVTVREVTLPLPR---PQDLKLRDVTHSTMNVFWEPVPGKVRK--YIVRYKTPEE-DVKE 445
Query: 379 VEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGPRPRPRPVPRAPT 437
VEV T+L+ L T Y V+V+A G ++A+ T RPVP APT
Sbjct: 446 VEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT--------RPVP-APT 495
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 118 bits (296), Expect = 9e-27
Identities = 106/384 (27%), Positives = 168/384 (43%), Gaps = 33/384 (8%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++ L+D S S+ + F VR F+ LV +G+ R L P E+ S+
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ +AVR + G+T TGLAL Y E F +G+R GV K+ + +TDG S D + P
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIP 277
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSILDA 212
P + L++ GV +F + + EL AS P H++ V + D +H +V+ L ++
Sbjct: 278 PSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSR 337
Query: 213 MRPQQLHATEITSSGFRLAWPP--LLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIW 270
+ Q EI +S + PP L+T++ + + PG + ++ T
Sbjct: 338 VEEQD---REIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPT---- 390
Query: 271 AGLDPD---TDYDV-ALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAA 326
G PD D V + V ++ + L QI A G G E+ A
Sbjct: 391 RGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTET--------TLA 442
Query: 327 LPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLR---GGEAQRVEVPA 383
LP + +++ S+RV W G A GY + + PL G+ + +++
Sbjct: 443 LPMASD-----LLLYDVTENSMRVKWDAVPG---ASGYLILYAPLTEGLAGDEKEMKIGE 494
Query: 384 GRNCTTLQGLAPGTAYLVTVTAAF 407
L GL P T Y VTV A F
Sbjct: 495 THTDIELSGLLPNTEYTVTVYAMF 518
Score = 105 bits (261), Expect = 1e-22
Identities = 57/174 (32%), Positives = 95/174 (54%), Gaps = 5/174 (2%)
Query: 26 PPAS----APRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPL-PLGTGALRASLVHVGS 80
PPA A + DL+F++D S S+ F+++ F+ V L +GT + ++V
Sbjct: 1020 PPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTD 1079
Query: 81 RPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLV 140
P TEF + + E DA++ + + G+T TG A+ Y ++ LF SG R G+PKV+V
Sbjct: 1080 DPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIV 1139
Query: 141 WVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD 194
+TDG S D V +E++ G ++F + ++ EL + S P+ +H+ FVD
Sbjct: 1140 VITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVD 1193
Score = 56.6 bits (135), Expect = 4e-08
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 21/219 (9%)
Query: 216 QQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLDP 275
Q L E+T+ FR+ W P L+AD G + L +P G L + GL+P
Sbjct: 628 QYLEIDEVTTDSFRVTWHP-LSADEGLHKLMWIP-VYGGKTEEVVLKEEQDSHVIEGLEP 685
Query: 276 DTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPT--QLAALPAPEEA 333
T+Y+V+L+ + + V G + PA T ++ + +
Sbjct: 686 GTEYEVSLLAVLDDGSESEVVTAV---------GTTLDSFWTEPATTIVPTTSVTSVFQT 736
Query: 334 GPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQR----VEVPAGRNCTT 389
G +V+ SLRV W + + + V + +G + V VP +N
Sbjct: 737 GIRNLVVGDETTSSLRVKW--DISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794
Query: 390 LQGLAPGTAYLVTVTAAFRSGRESALSA--KACTPDGPR 426
L+ L P T Y VTVT + G ++SA K GP+
Sbjct: 795 LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQ 833
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/232 (25%), Positives = 90/232 (38%), Gaps = 39/232 (16%)
Query: 199 HIIVQELRGSILDAMRPQ--QLHATEITSSGFRLAWPPLLTADSGYYVLEL-VPSAQPGA 255
H + LRG+ P L ++T + R+ W + A SGY +L + G
Sbjct: 428 HTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGD 486
Query: 256 ARRQQLPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPES 315
+ ++ TD +GL P+T+Y V + G AS P +
Sbjct: 487 EKEMKIGETHTDIELSGLLPNTEYTVTVY-------------------AMFGEEASDPVT 527
Query: 316 GAGPAPTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGE 375
G T LA P P + IS+ S R++W P S GY + + G E
Sbjct: 528 G---QETTLALSP------PRNLRISNVGSNSARLTWDPT--SRQINGYRIVYNNADGTE 576
Query: 376 AQRVEVPAGRNCTT--LQGLAPGTAYLVTVTAAFRSGRESALSAKACTPDGP 425
VEV TT L+GL P T Y + + + + G+ L+ T + P
Sbjct: 577 INEVEVDP---ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVP 625
Score = 46.2 bits (108), Expect = 6e-05
Identities = 47/200 (23%), Positives = 77/200 (38%), Gaps = 35/200 (17%)
Query: 215 PQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDWIWAGLD 274
P+ L + + S+ RL W P +GY +V + G + T + GL
Sbjct: 538 PRNLRISNVGSNSARLTWDPTSRQINGY---RIVYNNADGTEINEVEVDPITTFPLKGLT 594
Query: 275 PDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALPAPEEAG 334
P T+Y +A+ + G S P +G E
Sbjct: 595 PLTEYTIAIFSIYD-------------------EGQSEPLTGV---------FTTEEVPA 626
Query: 335 PERIVISHARPRSLRVSWAPALGSAAALGYH-VQFGPLRGGEAQRVEVPAGRNCTTLQGL 393
+ + I S RV+W P +A G H + + P+ GG+ + V + ++ ++GL
Sbjct: 627 QQYLEIDEVTTDSFRVTWHPL---SADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGL 683
Query: 394 APGTAYLVTVTAAFRSGRES 413
PGT Y V++ A G ES
Sbjct: 684 EPGTEYEVSLLAVLDDGSES 703
Score = 37.0 bits (84), Expect = 0.036
Identities = 39/162 (24%), Positives = 60/162 (37%), Gaps = 31/162 (19%)
Query: 261 LPGNATDWIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPA 320
+PG+ + + L PDT+Y V + P I + PG + P S
Sbjct: 786 VPGSQNNLLLKPLLPDTEYKVTVTP----------IYTDGEGVSVSAPGKTLPSS----- 830
Query: 321 PTQLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLR-GGEAQRV 379
GP+ + +S LR++W P S+ GY + + P+ G
Sbjct: 831 -------------GPQNLRVSEEWYNRLRITWDPP--SSPVKGYRIVYKPVSVPGPTLET 875
Query: 380 EVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGRESALSAKACT 421
V A N + L G Y V + A+ SG AL+ T
Sbjct: 876 FVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKT 917
Score = 32.3 bits (72), Expect = 0.89
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 13/110 (11%)
Query: 333 AGPERI---VISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRVEVPAGRNCTT 389
A P R+ VISH S+++SW G GY + P GG+ ++ +
Sbjct: 31 APPTRLRYNVISHD---SIQISWKAPRGKFG--GYKLLVTPTSGGKTNQLNLQNTATKAI 85
Query: 390 LQGLAPGTAYLVTVTAAFRSGRESALSAKACTPD-----GPRPRPRPVPR 434
+QGL P Y V + A + + D P+PR + V R
Sbjct: 86 IQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDR 135
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 102 bits (255), Expect = 5e-22
Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+ L+D S SV F V+ FV Q+V L + R LV SR TEFP G++ +
Sbjct: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
+ AV A T TGLAL + E F+EA GARP VP+V + TDG S D
Sbjct: 323 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
+ K+ G+ ++ V G+ EL AS PAE H+ + D + +++ LRGSI
Sbjct: 383 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
Score = 95.5 bits (236), Expect = 9e-20
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)
Query: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
GP DL+F++DSS SV +EF +R+F+ L+ L +G A R ++ S+ +
Sbjct: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
Query: 85 EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141
FP S E + A+R T TGLA+ YA F+ A GARP VP+V V
Sbjct: 85 VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
Query: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
VTDG D V + + G+ ++ V R + L A AS P ++H+ V+ DL
Sbjct: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 102 bits (255), Expect = 5e-22
Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+ L+D S SV F V+ FV Q+V L + R LV SR TEFP G++ +
Sbjct: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
+ AV A T TGLAL + E F+EA GARP VP+V + TDG S D
Sbjct: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
+ K+ G+ ++ V G+ EL AS PAE H+ + D + +++ LRGSI
Sbjct: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 483
Score = 95.5 bits (236), Expect = 9e-20
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)
Query: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
GP DL+F++DSS SV +EF +R+F+ L+ L +G A R ++ S+ +
Sbjct: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
Query: 85 EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141
FP S E + A+R T TGLA+ YA F+ A GARP VP+V V
Sbjct: 85 VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
Query: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
VTDG D V + + G+ ++ V R + L A AS P ++H+ V+ DL
Sbjct: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 102 bits (255), Expect = 5e-22
Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+ L+D S SV F V+ FV Q+V L + R LV SR TEFP G++ +
Sbjct: 345 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 404
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
+ AV A T TGLAL + E F+EA GARP VP+V + TDG S D
Sbjct: 405 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 464
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
+ K+ G+ ++ V G+ EL AS PAE H+ + D + +++ LRGSI
Sbjct: 465 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 524
Score = 95.5 bits (236), Expect = 9e-20
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)
Query: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
GP DL+F++DSS SV +EF +R+F+ L+ L +G A R ++ S+ +
Sbjct: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
Query: 85 EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141
FP S E + A+R T TGLA+ YA F+ A GARP VP+V V
Sbjct: 85 VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
Query: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
VTDG D V + + G+ ++ V R + L A AS P ++H+ V+ DL
Sbjct: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 99.8 bits (247), Expect = 5e-21
Identities = 56/165 (33%), Positives = 87/165 (52%), Gaps = 3/165 (1%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
R DL+F++DSS SV+ +++++V+EF+ ++ L +G R L+ GS EF
Sbjct: 55 RADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTF 114
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSS 148
+ AV+ T TGLA+ YA F+EA GARP VP+V++ VTDG
Sbjct: 115 KRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQ 174
Query: 149 DPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV 193
D V + +D G+ +F + G+ +F L + S P E H+ V
Sbjct: 175 DSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLV 219
Score = 86.7 bits (213), Expect = 4e-17
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+F++D S S+ F V++FV ++ L + A R L+ ++ +TEF +S
Sbjct: 655 DLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNS 714
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
+ + AV + TGLAL + E+ F + GARP VP+ + TDG + D
Sbjct: 715 AKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDD 774
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
V + K G+T++ V G+ EL AS P KHL + D + I ++L+ I
Sbjct: 775 VSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKLKKGI 834
Query: 210 LDAM 213
+A+
Sbjct: 835 CEAL 838
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 99.8 bits (247), Expect = 5e-21
Identities = 56/165 (33%), Positives = 87/165 (52%), Gaps = 3/165 (1%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
R DL+F++DSS SV+ +++++V+EF+ ++ L +G R L+ GS EF
Sbjct: 55 RADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTF 114
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSS 148
+ AV+ T TGLA+ YA F+EA GARP VP+V++ VTDG
Sbjct: 115 KRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQ 174
Query: 149 DPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV 193
D V + +D G+ +F + G+ +F L + S P E H+ V
Sbjct: 175 DSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLV 219
Score = 86.7 bits (213), Expect = 4e-17
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+F++D S S+ F V++FV ++ L + A R L+ ++ +TEF +S
Sbjct: 655 DLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNS 714
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
+ + AV + TGLAL + E+ F + GARP VP+ + TDG + D
Sbjct: 715 AKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDD 774
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
V + K G+T++ V G+ EL AS P KHL + D + I ++L+ I
Sbjct: 775 VSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKLKKGI 834
Query: 210 LDAM 213
+A+
Sbjct: 835 CEAL 838
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 94.0 bits (232), Expect = 2e-19
Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 1/177 (0%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+FL+D S SV F V++F+ Q+V L + + LV S EFP G+ +
Sbjct: 275 DLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHT 334
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ + AVR + T TG AL Y + F +SGARPG KV + TDG S D +
Sbjct: 335 KKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYIND 394
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAP-AEKHLHFVDVDDLHIIVQELRGSI 209
++ KDLG +F V G EL AS P AE + + D ++ I ++L+ I
Sbjct: 395 AAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKKI 451
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/164 (34%), Positives = 83/164 (50%), Gaps = 3/164 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+F++DSS SV EF +V+ F+ Q++ L +G A R +V+ S EF H S
Sbjct: 41 DLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFSLRAHVS 100
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR---PGVPKVLVWVTDGGSSDP 150
A AVR T TGLA+ +A + F +A G R P + KV++ VTDG D
Sbjct: 101 KAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTDGRPQDS 160
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD 194
V + GV +F + G + L AS P ++H+ +V+
Sbjct: 161 VQDVSARARASGVELFAIGVGSVDKATLRQIASEPQDEHVDYVE 204
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 89.7 bits (221), Expect = 5e-18
Identities = 62/179 (34%), Positives = 86/179 (48%), Gaps = 6/179 (3%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+FLLD+S+SV +F +VR++V LV +G R +V RP T F G S
Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
E + A R A G+T+TG AL Y + F+ +G RP +V + +TDG S D
Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELRGSI 209
V G+ +F V G EL AS P K H V D + I ++RG +
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEP--KSAHVFHVSDFNAI-DKIRGKL 213
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 87.8 bits (216), Expect = 2e-17
Identities = 58/192 (30%), Positives = 91/192 (47%), Gaps = 3/192 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+DSS ++ F VREF+ +V L +G +LV P+TEF + +
Sbjct: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSDPV 151
+ + + G TG L Y + +A+G+R GVP+V+V +TDG S D +
Sbjct: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGL 158
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHL-HFVDVDDLHIIVQELRGSIL 210
P ELK V VF + + L AS P H+ + + LH IV L +
Sbjct: 159 ALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVH 218
Query: 211 DAMRPQQLHATE 222
++ P++ TE
Sbjct: 219 SSVSPERAGDTE 230
Score = 76.6 bits (187), Expect = 4e-14
Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + + D++FLLD SA+V F VR+FV LV L +G +R LV P TE
Sbjct: 631 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 690
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGA--RPGVPKVLVWV 142
F + + +R + G +TG AL Y F EA G+ R VP++L+ +
Sbjct: 691 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 750
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIV 202
T G S D L G+ F V + N EL A P+ +L +DD
Sbjct: 751 TAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL----MDDF---- 802
Query: 203 QELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
S L A+ PQQL PL T SG +E VP AQP + R
Sbjct: 803 -----SSLPAL-PQQL-------------IQPLTTYVSG--GVEEVPLAQPESKR 836
Score = 75.5 bits (184), Expect = 9e-14
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S+++ F+ +R+F+ +++ L +G ++ ++ EF F H +
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASG--ARPGVPKVLVWVTDGGSSDP 150
AVR G +TG AL + + LF ++G A G+PK+LV +T G S D
Sbjct: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 564
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAA 182
+ P QELK + F + + EL A
Sbjct: 565 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 27 PASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEF 86
P + D++FL+D S S EF VR + +LV L +G R +++ P EF
Sbjct: 1226 PGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEF 1284
Query: 87 PFGQHSSGEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVT 143
HSS + Q+AV+ + G + G AL Y +F G+R GVP+ LV ++
Sbjct: 1285 LLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLIS 1344
Query: 144 DGGSSDPVGPPMQELKDLGVTVFIVS 169
G S D V P ELK GV F ++
Sbjct: 1345 SGKSDDEVDDPAVELKQFGVAPFTIA 1370
Score = 72.0 bits (175), Expect = 1e-12
Identities = 58/187 (31%), Positives = 88/187 (47%), Gaps = 16/187 (8%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S + F+ + +F+ L+ LP+GT +R +V P T F +S+
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
Query: 94 GEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSDP 150
AV+A G+ + GLAL + E F A G+R GVP+VLV ++ G SSD
Sbjct: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELR--GS 208
+ + LK V F L A A++ AE H D+L V E R G
Sbjct: 362 IRYGVVALKQASVFSF----------GLGAQAASRAELQ-HIATDDNLVFTVPEFRSFGD 410
Query: 209 ILDAMRP 215
+ + + P
Sbjct: 411 LQEKLLP 417
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 7/152 (4%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + D++FL+DSS V F+ +R+FV ++V L +G +R +V + + E
Sbjct: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1487
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWV 142
F + S DA+R R G +TG AL + LF +++G+R GVP+ LV V
Sbjct: 1488 FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLV 1547
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGN 174
G S D V Q ++ G IVS G G+
Sbjct: 1548 LGGKSQDDVSRFAQVIRSSG----IVSLGVGD 1575
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 6/172 (3%)
Query: 20 SGAERGPPASAPRG--DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVH 77
SG P + P D++FL D SA++ +F VR+F+ +++ L + R ++
Sbjct: 821 SGGVEEVPLAQPESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQ 879
Query: 78 VGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PG 134
E F +H S + V+ + G + G AL YA+ +F +++G+R G
Sbjct: 880 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 939
Query: 135 VPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPA 186
V + LV + G SSD V P LK GV FI + EL +PA
Sbjct: 940 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA 991
Score = 33.9 bits (76), Expect = 0.31
Identities = 43/183 (23%), Positives = 71/183 (38%), Gaps = 24/183 (13%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTG-------ALRASLVHVGSRPY--- 83
D+ F+LDS+ + + ++F+ +++++ LV L + A A + H S
Sbjct: 2619 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2678
Query: 84 ------TEFPFGQHSSGEAAQDAV-RASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP 136
EF + S E D + R Q G G A+ Y E +F A R
Sbjct: 2679 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD--L 2736
Query: 137 KVLVWVTDGGSSDPVGPPMQ----ELKDLGVTVFIVSTGRG-NFLELSAAASAPAEKHLH 191
K++V + G + Q + K G ++ GR N E+ AS P +
Sbjct: 2737 KIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFK 2796
Query: 192 FVD 194
VD
Sbjct: 2797 LVD 2799
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 86.3 bits (212), Expect = 5e-17
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+F++DSS SV EF++V+ FV +++ L +G R ++V+ S EF ++
Sbjct: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR---PGVPKVLVWVTDGGSSDP 150
++ + AV T +GLA+ A ++ F +GAR +PKV + VTDG D
Sbjct: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD 194
V + G+ ++ V R + L AS P E+H+ +V+
Sbjct: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVE 246
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 82.8 bits (203), Expect = 6e-16
Identities = 56/179 (31%), Positives = 89/179 (49%), Gaps = 5/179 (2%)
Query: 17 LARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLV 76
LA G R +AP DL+F+LD S SV F V++++ + +G ++ +V
Sbjct: 21 LAEDGEVRSSCRTAPT-DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVV 79
Query: 77 HVGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP 136
P E P G + SGE AV + G+T TG A+ +A + LFA++S +
Sbjct: 80 QYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LT 136
Query: 137 KVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTG-RGNFLELSAAASAPAEKHLHFVD 194
K+ V +TDG S D V Q +D +T+F + G EL A A+ P+ ++ +V+
Sbjct: 137 KIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVE 195
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 82.8 bits (203), Expect = 6e-16
Identities = 53/157 (33%), Positives = 75/157 (47%), Gaps = 2/157 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D+MFLLD S SV F R + F + L + +R S P+ EFP S+
Sbjct: 51 DIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFST 110
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ + ++ + G T T LAL Y + G VP++L+ VTDG S V
Sbjct: 111 QQEVKARIKRMVFKGGRTETELALKYLLHR--GLPGGRNASVPQILIIVTDGKSQGDVAL 168
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHL 190
P ++LK+ GVTVF V + EL A AS P +H+
Sbjct: 169 PSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHV 205
Score = 73.2 bits (178), Expect = 5e-13
Identities = 42/138 (30%), Positives = 70/138 (50%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+F+LD+SASV F++++ FV + + LV GS+ T F +
Sbjct: 531 DLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTAFGLDTKPT 590
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
A A+ + G G AL++ +++ GARPGVPK +V +T G ++
Sbjct: 591 RAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKAVVVLTGGRGAEDAAV 650
Query: 154 PMQELKDLGVTVFIVSTG 171
P Q+L++ G++V +V G
Sbjct: 651 PAQKLRNNGISVLVVGVG 668
Score = 50.4 bits (119), Expect = 3e-06
Identities = 56/191 (29%), Positives = 79/191 (41%), Gaps = 15/191 (7%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
R DL+FLLDSSA + F R + FV + V + R + P G++
Sbjct: 341 RVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEY 400
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP-KVLVWVTDGGSSDP 150
++ R G T TG AL A E+ F A+ P +V+V +T+ S D
Sbjct: 401 QDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPRRVVVLLTESHSEDE 460
Query: 151 VGPP-----MQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKH-LHFVDVDDLHIIVQE 204
V P +EL LGV V EL +P KH + + D DL + E
Sbjct: 461 VAGPARHARARELLLLGVGSEAVRA------ELEEITGSP--KHVMVYSDPQDLFNQIPE 512
Query: 205 LRGSILDAMRP 215
L+G + RP
Sbjct: 513 LQGKLCSRQRP 523
>gi|205277471 cochlin precursor [Homo sapiens]
Length = 550
Score = 79.3 bits (194), Expect = 6e-15
Identities = 44/141 (31%), Positives = 71/141 (50%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
+ D+ FL+D S ++ F+ + FVG++ L +GT LV P EF
Sbjct: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
+S + A++ R G+++TG AL + ++ F +G R G+PKV+V DG SD +
Sbjct: 223 TSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
Query: 152 GPPMQELKDLGVTVFIVSTGR 172
++ GV VFIVS +
Sbjct: 283 EEAGIVAREFGVNVFIVSVAK 303
Score = 66.2 bits (160), Expect = 6e-11
Identities = 54/186 (29%), Positives = 77/186 (41%), Gaps = 4/186 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
++ FL+D S+SV F + EFV + + + + V TEF F +S+
Sbjct: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
E +R G T TG A+ + +F + LV VTDG S D V
Sbjct: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN--KNFLVIVTDGQSYDDVQG 484
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQE-LRGSILD 211
P D G+T+F V +L AS P E H F + L IV + +RG D
Sbjct: 485 PAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
Query: 212 AMRPQQ 217
+ QQ
Sbjct: 545 FLESQQ 550
>gi|4758022 cochlin precursor [Homo sapiens]
Length = 550
Score = 79.3 bits (194), Expect = 6e-15
Identities = 44/141 (31%), Positives = 71/141 (50%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
+ D+ FL+D S ++ F+ + FVG++ L +GT LV P EF
Sbjct: 163 KADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNF 222
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
+S + A++ R G+++TG AL + ++ F +G R G+PKV+V DG SD +
Sbjct: 223 TSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDI 282
Query: 152 GPPMQELKDLGVTVFIVSTGR 172
++ GV VFIVS +
Sbjct: 283 EEAGIVAREFGVNVFIVSVAK 303
Score = 66.2 bits (160), Expect = 6e-11
Identities = 54/186 (29%), Positives = 77/186 (41%), Gaps = 4/186 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
++ FL+D S+SV F + EFV + + + + V TEF F +S+
Sbjct: 367 NIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYST 426
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
E +R G T TG A+ + +F + LV VTDG S D V
Sbjct: 427 KENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPN--KNFLVIVTDGQSYDDVQG 484
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQE-LRGSILD 211
P D G+T+F V +L AS P E H F + L IV + +RG D
Sbjct: 485 PAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRD 544
Query: 212 AMRPQQ 217
+ QQ
Sbjct: 545 FLESQQ 550
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 76.6 bits (187), Expect = 4e-14
Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + + D++FLLD SA+V F VR+FV LV L +G +R LV P TE
Sbjct: 425 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 484
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGA--RPGVPKVLVWV 142
F + + +R + G +TG AL Y F EA G+ R VP++L+ +
Sbjct: 485 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 544
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIV 202
T G S D L G+ F V + N EL A P+ +L +DD
Sbjct: 545 TAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL----MDDF---- 596
Query: 203 QELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
S L A+ PQQL PL T SG +E VP AQP + R
Sbjct: 597 -----SSLPAL-PQQL-------------IQPLTTYVSG--GVEEVPLAQPESKR 630
Score = 75.5 bits (184), Expect = 9e-14
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S+++ F+ +R+F+ +++ L +G ++ ++ EF F H +
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASG--ARPGVPKVLVWVTDGGSSDP 150
AVR G +TG AL + + LF ++G A G+PK+LV +T G S D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 358
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAA 182
+ P QELK + F + + EL A
Sbjct: 359 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 390
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 27 PASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEF 86
P + D++FL+D S S EF VR + +LV L +G R +++ P EF
Sbjct: 1020 PGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEF 1078
Query: 87 PFGQHSSGEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVT 143
HSS + Q+AV+ + G + G AL Y +F G+R GVP+ LV ++
Sbjct: 1079 LLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLIS 1138
Query: 144 DGGSSDPVGPPMQELKDLGVTVFIVS 169
G S D V P ELK GV F ++
Sbjct: 1139 SGKSDDEVDDPAVELKQFGVAPFTIA 1164
Score = 72.8 bits (177), Expect = 6e-13
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 16/193 (8%)
Query: 28 ASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFP 87
A+ D++FL+D S + F+ + +F+ L+ LP+GT +R +V P T F
Sbjct: 30 AAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFS 89
Query: 88 FGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTD 144
+S+ AV+A G+ + GLAL + E F A G+R GVP+VLV ++
Sbjct: 90 LDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISA 149
Query: 145 GGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQE 204
G SSD + + LK V F L A A++ AE H D+L V E
Sbjct: 150 GPSSDEIRYGVVALKQASVFSF----------GLGAQAASRAELQ-HIATDDNLVFTVPE 198
Query: 205 LR--GSILDAMRP 215
R G + + + P
Sbjct: 199 FRSFGDLQEKLLP 211
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 7/152 (4%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + D++FL+DSS V F+ +R+FV ++V L +G +R +V + + E
Sbjct: 1222 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1281
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWV 142
F + S DA+R R G +TG AL + LF +++G+R GVP+ LV V
Sbjct: 1282 FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLV 1341
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGN 174
G S D V Q ++ G IVS G G+
Sbjct: 1342 LGGKSQDDVSRFAQVIRSSG----IVSLGVGD 1369
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 6/172 (3%)
Query: 20 SGAERGPPASAPRG--DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVH 77
SG P + P D++FL D SA++ +F VR+F+ +++ L + R ++
Sbjct: 615 SGGVEEVPLAQPESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQ 673
Query: 78 VGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PG 134
E F +H S + V+ + G + G AL YA+ +F +++G+R G
Sbjct: 674 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 733
Query: 135 VPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPA 186
V + LV + G SSD V P LK GV FI + EL +PA
Sbjct: 734 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA 785
Score = 33.9 bits (76), Expect = 0.31
Identities = 43/183 (23%), Positives = 71/183 (38%), Gaps = 24/183 (13%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTG-------ALRASLVHVGSRPY--- 83
D+ F+LDS+ + + ++F+ +++++ LV L + A A + H S
Sbjct: 2413 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2472
Query: 84 ------TEFPFGQHSSGEAAQDAV-RASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP 136
EF + S E D + R Q G G A+ Y E +F A R
Sbjct: 2473 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD--L 2530
Query: 137 KVLVWVTDGGSSDPVGPPMQ----ELKDLGVTVFIVSTGRG-NFLELSAAASAPAEKHLH 191
K++V + G + Q + K G ++ GR N E+ AS P +
Sbjct: 2531 KIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFK 2590
Query: 192 FVD 194
VD
Sbjct: 2591 LVD 2593
>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
sapiens]
Length = 1036
Score = 76.6 bits (187), Expect = 4e-14
Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + + D++FLLD SA+V F VR+FV LV L +G +R LV P TE
Sbjct: 224 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 283
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGA--RPGVPKVLVWV 142
F + + +R + G +TG AL Y F EA G+ R VP++L+ +
Sbjct: 284 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 343
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIV 202
T G S D L G+ F V + N EL A P+ +L +DD
Sbjct: 344 TAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL----MDDF---- 395
Query: 203 QELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
S L A+ PQQL PL T SG +E VP AQP + R
Sbjct: 396 -----SSLPAL-PQQL-------------IQPLTTYVSG--GVEEVPLAQPESKR 429
Score = 75.5 bits (184), Expect = 9e-14
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S+++ F+ +R+F+ +++ L +G ++ ++ EF F H +
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASG--ARPGVPKVLVWVTDGGSSDP 150
AVR G +TG AL + + LF ++G A G+PK+LV +T G S D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAA 182
+ P QELK + F + + EL A
Sbjct: 158 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 27 PASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEF 86
P + D++FL+D S S EF VR + +LV L +G R +++ P EF
Sbjct: 819 PGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEF 877
Query: 87 PFGQHSSGEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVT 143
HSS + Q+AV+ + G + G AL Y +F G+R GVP+ LV ++
Sbjct: 878 LLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLIS 937
Query: 144 DGGSSDPVGPPMQELKDLGVTVFIVS 169
G S D V P ELK GV F ++
Sbjct: 938 SGKSDDEVDDPAVELKQFGVAPFTIA 963
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 6/172 (3%)
Query: 20 SGAERGPPASAPRG--DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVH 77
SG P + P D++FL D SA++ +F VR+F+ +++ L + R ++
Sbjct: 414 SGGVEEVPLAQPESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQ 472
Query: 78 VGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PG 134
E F +H S + V+ + G + G AL YA+ +F +++G+R G
Sbjct: 473 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 532
Query: 135 VPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPA 186
V + LV + G SSD V P LK GV FI + EL +PA
Sbjct: 533 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA 584
>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
sapiens]
Length = 1237
Score = 76.6 bits (187), Expect = 4e-14
Identities = 75/235 (31%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + + D++FLLD SA+V F VR+FV LV L +G +R LV P TE
Sbjct: 425 PEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTE 484
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGA--RPGVPKVLVWV 142
F + + +R + G +TG AL Y F EA G+ R VP++L+ +
Sbjct: 485 FSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLL 544
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIV 202
T G S D L G+ F V + N EL A P+ +L +DD
Sbjct: 545 TAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL----MDDF---- 596
Query: 203 QELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAAR 257
S L A+ PQQL PL T SG +E VP AQP + R
Sbjct: 597 -----SSLPAL-PQQL-------------IQPLTTYVSG--GVEEVPLAQPESKR 630
Score = 75.5 bits (184), Expect = 9e-14
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S+++ F+ +R+F+ +++ L +G ++ ++ EF F H +
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASG--ARPGVPKVLVWVTDGGSSDP 150
AVR G +TG AL + + LF ++G A G+PK+LV +T G S D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 358
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAA 182
+ P QELK + F + + EL A
Sbjct: 359 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 390
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 27 PASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEF 86
P + D++FL+D S S EF VR + +LV L +G R +++ P EF
Sbjct: 1020 PGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEF 1078
Query: 87 PFGQHSSGEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVT 143
HSS + Q+AV+ + G + G AL Y +F G+R GVP+ LV ++
Sbjct: 1079 LLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLIS 1138
Query: 144 DGGSSDPVGPPMQELKDLGVTVFIVS 169
G S D V P ELK GV F ++
Sbjct: 1139 SGKSDDEVDDPAVELKQFGVAPFTIA 1164
Score = 72.8 bits (177), Expect = 6e-13
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 16/193 (8%)
Query: 28 ASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFP 87
A+ D++FL+D S + F+ + +F+ L+ LP+GT +R +V P T F
Sbjct: 30 AAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFS 89
Query: 88 FGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTD 144
+S+ AV+A G+ + GLAL + E F A G+R GVP+VLV ++
Sbjct: 90 LDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISA 149
Query: 145 GGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQE 204
G SSD + + LK V F L A A++ AE H D+L V E
Sbjct: 150 GPSSDEIRYGVVALKQASVFSF----------GLGAQAASRAELQ-HIATDDNLVFTVPE 198
Query: 205 LR--GSILDAMRP 215
R G + + + P
Sbjct: 199 FRSFGDLQEKLLP 211
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 6/172 (3%)
Query: 20 SGAERGPPASAPRG--DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVH 77
SG P + P D++FL D SA++ +F VR+F+ +++ L + R ++
Sbjct: 615 SGGVEEVPLAQPESKRDILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQ 673
Query: 78 VGSRPYTEFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PG 134
E F +H S + V+ + G + G AL YA+ +F +++G+R G
Sbjct: 674 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 733
Query: 135 VPKVLVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPA 186
V + LV + G SSD V P LK GV FI + EL +PA
Sbjct: 734 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA 785
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 75.5 bits (184), Expect = 9e-14
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+D S+++ F+ +R+F+ +++ L +G ++ ++ EF F H +
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASG--ARPGVPKVLVWVTDGGSSDP 150
AVR G +TG AL + + LF ++G A G+PK+LV +T G S D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 157
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAA 182
+ P QELK + F + + EL A
Sbjct: 158 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 74.7 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 4/146 (2%)
Query: 27 PASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEF 86
P + D++FL+D S S EF VR + +LV L +G R +++ P EF
Sbjct: 619 PGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEF 677
Query: 87 PFGQHSSGEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVT 143
HSS + Q+AV+ + G + G AL Y +F G+R GVP+ LV ++
Sbjct: 678 LLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLIS 737
Query: 144 DGGSSDPVGPPMQELKDLGVTVFIVS 169
G S D V P ELK GV F ++
Sbjct: 738 SGKSDDEVDDPAVELKQFGVAPFTIA 763
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/152 (32%), Positives = 76/152 (50%), Gaps = 7/152 (4%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTE 85
P + D++FL+DSS V F+ +R+FV ++V L +G +R +V + + E
Sbjct: 821 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 880
Query: 86 FPFGQHSSGEAAQDAVRASAQRMGD-THTGLALVYAKEQLFAEASGAR--PGVPKVLVWV 142
F + S DA+R R G +TG AL + LF +++G+R GVP+ LV V
Sbjct: 881 FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLV 940
Query: 143 TDGGSSDPVGPPMQELKDLGVTVFIVSTGRGN 174
G S D V Q ++ G IVS G G+
Sbjct: 941 LGGKSQDDVSRFAQVIRSSG----IVSLGVGD 968
Score = 62.0 bits (149), Expect = 1e-09
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Query: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
G P + R D++FL D SA++ +F VR+F+ +++ L + R ++
Sbjct: 222 GTPEESKR-DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKV 279
Query: 85 EFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PGVPKVLVW 141
E F +H S + V+ + G + G AL YA+ +F +++G+R GV + LV
Sbjct: 280 ESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVL 339
Query: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPA 186
+ G SSD V P LK GV FI + EL +PA
Sbjct: 340 LVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA 384
Score = 33.9 bits (76), Expect = 0.31
Identities = 43/183 (23%), Positives = 71/183 (38%), Gaps = 24/183 (13%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTG-------ALRASLVHVGSRPY--- 83
D+ F+LDS+ + + ++F+ +++++ LV L + A A + H S
Sbjct: 2012 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2071
Query: 84 ------TEFPFGQHSSGEAAQDAV-RASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP 136
EF + S E D + R Q G G A+ Y E +F A R
Sbjct: 2072 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD--L 2129
Query: 137 KVLVWVTDGGSSDPVGPPMQ----ELKDLGVTVFIVSTGRG-NFLELSAAASAPAEKHLH 191
K++V + G + Q + K G ++ GR N E+ AS P +
Sbjct: 2130 KIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFK 2189
Query: 192 FVD 194
VD
Sbjct: 2190 LVD 2192
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/177 (33%), Positives = 87/177 (49%), Gaps = 17/177 (9%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++ +LD S S+ Y + V F+ L+ + +G + +V G EF ++SS
Sbjct: 172 DIVIVLDGSNSI--YPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
Query: 94 GEAAQDAVRASAQRMG-DTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSD--P 150
E A + QR G T T L + A+++ F EA GAR GV KV+V VTDG S D
Sbjct: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHR 289
Query: 151 VGPPMQELKDLGVTVFIV----STGRGNFL------ELSAAASAPAEKHLHFVDVDD 197
+ +Q+ +D + F + S RGN E+ + AS P EK HF +V D
Sbjct: 290 LKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEK--HFFNVSD 344
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 74.3 bits (181), Expect = 2e-13
Identities = 46/154 (29%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
+ D+MFL+DSS S+ FS+++ F+ LV+ +G ++ +V EF +
Sbjct: 620 KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRF 679
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
S +A+ A T TG AL + Q F+ GARP + K L+ +TDG + D V
Sbjct: 680 MSQSDISNAIDQMAHIGQTTLTGSALSFV-SQYFSPTKGARPNIRKFLILITDGEAQDIV 738
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAP 185
P L+ GV ++ V N +L + P
Sbjct: 739 KEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP 772
Score = 69.7 bits (169), Expect = 5e-12
Identities = 48/167 (28%), Positives = 77/167 (46%), Gaps = 4/167 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+FL+D S S+ +F +++EF+ +V + +R + EFP G
Sbjct: 1000 DLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIG 1059
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSDPV 151
+ + Q G+TH G AL E F G+R G P+VL+ +TDG S D V
Sbjct: 1060 EKEISFQIENIKQIFGNTHIGAAL-REVEHYFRPDMGSRINTGTPQVLLVLTDGQSQDEV 1118
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
+ L+ G+ ++ V G + +L + AEK L + D+L
Sbjct: 1119 AQAAEALRHRGIDIYSVGIGDVDDQQL-IQITGTAEKKLTVHNFDEL 1164
Score = 64.7 bits (156), Expect = 2e-10
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 6/185 (3%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++F++DSS S+ + E++ +++F+ LV +G +R + P F +
Sbjct: 809 DVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGT 868
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGS--SD 149
++ G T+T AL ++ + +F EA G+R GVP+VL+ +TDG S +D
Sbjct: 869 KLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNKGVPQVLIVITDGESHDAD 927
Query: 150 PVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELRGSI 209
+ + L+D G+ V V N +EL A A + ++K+ L I ++ S+
Sbjct: 928 KLNATAKALRDKGILVLAVGIDGANPVELLAMAGS-SDKYFFVETFGGLKGIFSDVTASV 986
Query: 210 LDAMR 214
++ +
Sbjct: 987 CNSSK 991
Score = 62.4 bits (150), Expect = 8e-10
Identities = 42/159 (26%), Positives = 76/159 (47%), Gaps = 2/159 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FLLD S + S F ++ F+ + V+ L + +R LV + +
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP--GVPKVLVWVTDGGSSDPV 151
++ + R G +TG A+ ++++F+ +G+R GVP++ V VT S D V
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNV 348
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHL 190
L+ GVT+F + + +L AS PAE+++
Sbjct: 349 TKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYV 387
Score = 55.5 bits (132), Expect = 1e-07
Identities = 45/177 (25%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D+ L+D S S +F ++ F+ ++V + +R V EF ++S+
Sbjct: 436 DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ A+ Q G+T+TG AL + L VP LV +T+G S D +
Sbjct: 496 KQDLGKAIENIRQMGGNTNTGAALNFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILE 555
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDL----HIIVQEL 205
P L++ + V+ + N +L A EK +++V D D L + +VQE+
Sbjct: 556 PANRLREEHIRVYAIGIKEANQTQLREIAG--EEKRVYYVHDFDALKDIRNQVVQEI 610
Score = 51.6 bits (122), Expect = 1e-06
Identities = 45/184 (24%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL+DSS + F V+ F+ ++++ LP+ R +L + ++EF
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 94 GEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSDP 150
+ +R + +G + G AL A F+ + R P +LV + S D
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
Query: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQELRGSIL 210
V + L+ GV I+S G E + A A ++ H + V DL + Q + I
Sbjct: 147 VEEASKALRKDGVK--IISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHIIK 204
Query: 211 DAMR 214
D ++
Sbjct: 205 DVIK 208
Score = 38.5 bits (88), Expect = 0.012
Identities = 50/187 (26%), Positives = 75/187 (40%), Gaps = 24/187 (12%)
Query: 26 PPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLV-------APLPLGTGALRASLVHV 78
PP D FLLD+S ++ EF +R F+G L+ P TG A L H
Sbjct: 1957 PPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHA 2016
Query: 79 ---------GSRPYTEFPFGQHSSGEAAQDAVRASAQRM-GDTHTGLALVYAKEQLFAEA 128
S EF + S + V S +++ GD G AL + + +F
Sbjct: 2017 PPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLST 2076
Query: 129 SGARPGVPKVLVWVTDGGSSDPVGPPMQE----LKDLGVTVFIVSTGR-GNFLELSAAAS 183
R KV+ ++ G +S G +++ K G +F+ S G + EL AS
Sbjct: 2077 PNLRRN--KVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLAS 2134
Query: 184 APAEKHL 190
P + HL
Sbjct: 2135 HPLDHHL 2141
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 73.9 bits (180), Expect = 3e-13
Identities = 55/184 (29%), Positives = 81/184 (44%), Gaps = 4/184 (2%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D+ F++D S+SV F V +FV L + R V EF F ++SS
Sbjct: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+A++ G T TG A+ +A EQLF ++ +P K+++ +TDG S D V
Sbjct: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS---KPNKRKLMILITDGRSYDDVRI 626
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD-VDDLHIIVQELRGSILDA 212
P GV + + EL A+ PA H FVD D+LH V + +I
Sbjct: 627 PAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
Query: 213 MRPQ 216
Q
Sbjct: 687 FNSQ 690
Score = 71.2 bits (173), Expect = 2e-12
Identities = 36/136 (26%), Positives = 66/136 (48%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL FL+D S S+ F ++ + + L +G +V G P T F H++
Sbjct: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ A+ QR G ++ G A+ + + F++A+G R G P V+V + DG +D V
Sbjct: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
Query: 154 PMQELKDLGVTVFIVS 169
+ ++ G+ +F ++
Sbjct: 428 ASRLARESGINIFFIT 443
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 72.4 bits (176), Expect = 8e-13
Identities = 48/174 (27%), Positives = 83/174 (47%), Gaps = 2/174 (1%)
Query: 32 RGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQH 91
+ D+MFL+DSS S+ + F +++ F+ L+ + +G + +V + EF ++
Sbjct: 626 KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQLNRY 685
Query: 92 SSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPV 151
+ + DA+ + T TG AL + Q F + GAR G K L+ +TDG + D V
Sbjct: 686 FTQQEISDAIDRMSLINEGTLTGKALNFV-GQYFTHSKGARLGAKKFLILITDGVAQDDV 744
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDLHIIVQEL 205
P + L+ VT+F V N +L S + H + D L + ++L
Sbjct: 745 RDPARILRGKDVTIFSVGVYNANRSQLE-EISGDSSLVFHVENFDHLKALERKL 797
Score = 65.9 bits (159), Expect = 7e-11
Identities = 42/149 (28%), Positives = 70/149 (46%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D+ FL+D S+S+ +F +++ F+ ++ +G +R +V EF +S+
Sbjct: 442 DIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSN 501
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGSSDPVGP 153
+ A+ Q G T+TG AL Y + + VP L+ +TDG S+D V
Sbjct: 502 DIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTDRVVE 561
Query: 154 PMQELKDLGVTVFIVSTGRGNFLELSAAA 182
P + L+ +TV V G N +EL A
Sbjct: 562 PAKRLRAEQITVHAVGIGAANKIELQEIA 590
Score = 58.5 bits (140), Expect = 1e-08
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++F+LD S S+ + LV +G ++ + +P F +S+
Sbjct: 814 DVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSN 873
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSD-- 149
A + +R G+T+T AL +A LF E G+R V ++L+ +TDG S D
Sbjct: 874 RSAIIENLRKRRDTGGNTYTAKALKHANA-LFTEEHGSRIKQNVKQMLIVITDGESHDHD 932
Query: 150 PVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVD----VDDLHIIVQE 204
+ EL++ G+T+F V G+ N EL A + + +VD + D+ +VQE
Sbjct: 933 QLNDTALELRNKGITIFAVGVGKANQKELEGMAG--NKNNTIYVDNFDKLKDVFTLVQE 989
Score = 50.4 bits (119), Expect = 3e-06
Identities = 46/196 (23%), Positives = 79/196 (40%), Gaps = 5/196 (2%)
Query: 22 AERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSR 81
A++ P D++FL+DSS + F V+ F+ +++ LP+ R +L
Sbjct: 18 ADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDE 77
Query: 82 PYTEFPFGQHSSGEAAQDAVRASAQRMGDT-HTGLALVYAKEQLFAEASGA--RPGVPKV 138
++EF + ++ + Q +G + G AL A F+ R P +
Sbjct: 78 FHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPI 137
Query: 139 LVWVTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
LV + S D V + L+ GV I+S G E + A A + H + + DL
Sbjct: 138 LVVLASAESEDEVEEASKALQKDGVK--IISVGVQKASEENLKAMATSHFHFNLRTIRDL 195
Query: 199 HIIVQELRGSILDAMR 214
Q + I D +
Sbjct: 196 STFSQNMTQIIKDVTK 211
Score = 49.3 bits (116), Expect = 7e-06
Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 2/166 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D++FL D S VS+ +F + F+ L+ + + ++ + GS + +
Sbjct: 1005 DVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLT 1064
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR-PGVPKVLVWVTDGGSSDPVG 152
+ ++ ++ G AL A G R GVP+ LV +T G V
Sbjct: 1065 KTQWKTQIQNVSKSGGFPRIDFALKKVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVA 1124
Query: 153 PPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
++ LKDLG+ V ++ G + E + +EK + F D D L
Sbjct: 1125 DAVKTLKDLGICVLVLGIG-DVYKEHLLPITGNSEKIITFQDFDKL 1169
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 3/157 (1%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
DL+FL+D S ++ F+ + + + + +R L+ + T ++
Sbjct: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGAR--PGVPKVLVWVTDGGSSDPV 151
Q ++ + ++G ++TG A+ + F+E+ G+R GVP++ V VT S D V
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEV 354
Query: 152 GPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEK 188
L+ V VF +S N +L S P E+
Sbjct: 355 HDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQ 391
Score = 43.5 bits (101), Expect = 4e-04
Identities = 47/179 (26%), Positives = 75/179 (41%), Gaps = 25/179 (13%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQL-----VAPLPLGTGALRASLVHVGSRP------ 82
D+ FL+D+S V EF V+ F+ + +AP PL T L + + P
Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPL-TSTLGDRVAVLSYSPPGYMPN 2349
Query: 83 ------YTEFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVP 136
Y EF ++S + ++ S Q GD G AL + + +F R
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKN-- 2407
Query: 137 KVLVWVTDGGSS----DPVGPPMQELKDLGVTVFIVSTG-RGNFLELSAAASAPAEKHL 190
KV+ ++ G ++ D + K G ++F+ S G + N EL AS P + HL
Sbjct: 2408 KVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDHHL 2466
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 21/176 (11%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRAS----LVHVGSRPY------ 83
D++FL+D+S +++ EF V+ V ++ + + L + + + P+
Sbjct: 1963 DVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRK 2022
Query: 84 -----TEFPFGQHSSGEAAQDAVRASAQRM-GDTHTGLALVYAKEQLFAEASGARPGVPK 137
TEF F + + ++ ++ S Q++ G+ G AL++ E LF E R K
Sbjct: 2023 MGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRK--HK 2080
Query: 138 VLVWVTDGGS---SDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHL 190
V+ V+ G + + V K G +F++S G ++ AS P ++HL
Sbjct: 2081 VIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHL 2136
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/196 (31%), Positives = 89/196 (45%), Gaps = 22/196 (11%)
Query: 7 LGLALSLRLALARSGAERGPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPL 66
LG A R+ L R +ER +L+FL+D S+SV F FV +L++ P+
Sbjct: 64 LGQAFRRRVRLLRELSERL--------ELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPV 115
Query: 67 GTGALRASLVHVGSRPYTEFPFGQHSSGEAAQ-------DAVRASAQRMGDTHTGLALVY 119
A R ++V S+ Y S+ A Q + A + R G T+T A
Sbjct: 116 VPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQ 175
Query: 120 AKEQLFAEASGARPGVPKVLVWVTDGGSS--DPVGPPMQELKDLGVTVFIVSTGRGNFLE 177
A + L AR KV+ +TDG S+ DP P L+D GV +F +GN E
Sbjct: 176 AAQILL----HARENSTKVVFLITDGYSNGGDP-RPIAASLRDSGVEIFTFGIWQGNIRE 230
Query: 178 LSAAASAPAEKHLHFV 193
L+ AS P E+H + +
Sbjct: 231 LNDMASTPKEEHCYLL 246
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 63.5 bits (153), Expect = 4e-10
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 20/226 (8%)
Query: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
D+ FL+D S S+ ++F R++EFV ++ L SL+ F F + +
Sbjct: 150 DIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLF--SLMQYSEEFRIHFTFKEFQN 207
Query: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARPGVPKVLVWVTDGGS-SDPVG 152
+ V+ Q +G THT + +LF +GAR K+LV +TDG DP+G
Sbjct: 208 NPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLG 267
Query: 153 --PPMQELKDLGVTVFIVSTG-----RGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQE 204
+ E GV +++ G + EL+ AS P H+ V + + L I +
Sbjct: 268 YEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQ 327
Query: 205 LRGSILDAMRPQQLHAT-----EITSSGFRLAWP---PLLTADSGY 242
LR I A+ Q ++ E++ GF A PLL+ Y
Sbjct: 328 LREKIF-AIEGTQTGSSSSFEHEMSQEGFSAAITSNGPLLSTVGSY 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,500,473
Number of Sequences: 37866
Number of extensions: 1141725
Number of successful extensions: 8189
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 232
Number of HSP's that attempted gapping in prelim test: 7231
Number of HSP's gapped (non-prelim): 1069
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.