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Search of human proteins with 125490370
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125490370 type I hair keratin KA36 [Homo sapiens]
(431 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125490370 type I hair keratin KA36 [Homo sapiens] 875 0.0
gi|14917119 keratin 34 [Homo sapiens] 496 e-140
gi|94538345 keratin 35 [Homo sapiens] 495 e-140
gi|4504927 keratin 36 [Homo sapiens] 495 e-140
gi|14917115 keratin 31 [Homo sapiens] 478 e-135
gi|14917117 keratin 33A [Homo sapiens] 476 e-134
gi|116488398 keratin 32 [Homo sapiens] 473 e-133
gi|10337581 type I hair keratin 3B [Homo sapiens] 462 e-130
gi|148277620 type I hair keratin KA35 [Homo sapiens] 433 e-121
gi|15431318 keratin 38 [Homo sapiens] 413 e-115
gi|55770882 keratin 37 [Homo sapiens] 404 e-113
gi|15431310 keratin 14 [Homo sapiens] 343 2e-94
gi|4557701 keratin 17 [Homo sapiens] 338 7e-93
gi|24430192 keratin 16 [Homo sapiens] 333 2e-91
gi|24234699 keratin 19 [Homo sapiens] 326 2e-89
gi|24430190 keratin 15 [Homo sapiens] 323 1e-88
gi|131412225 keratin 13 isoform a [Homo sapiens] 322 5e-88
gi|131412228 keratin 13 isoform b [Homo sapiens] 317 1e-86
gi|4557699 keratin 12 [Homo sapiens] 297 1e-80
gi|195972866 keratin 10 [Homo sapiens] 295 7e-80
gi|27894337 keratin 20 [Homo sapiens] 294 1e-79
gi|153945736 keratin 27 [Homo sapiens] 286 3e-77
gi|114431246 keratin 25D [Homo sapiens] 278 5e-75
gi|192807292 keratin 24 [Homo sapiens] 276 3e-74
gi|31559829 keratin 25 [Homo sapiens] 273 2e-73
gi|31559815 keratin 26 [Homo sapiens] 263 3e-70
gi|55956899 keratin 9 [Homo sapiens] 254 1e-67
gi|40354195 keratin 18 [Homo sapiens] 252 4e-67
gi|4557888 keratin 18 [Homo sapiens] 252 4e-67
gi|27894339 keratin 23 [Homo sapiens] 240 2e-63
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 875 bits (2261), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLL 60
MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLL
Sbjct: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLL 60
Query: 61 PCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESR 120
PCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESR
Sbjct: 61 PCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESR 120
Query: 121 IQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYES 180
IQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYES
Sbjct: 121 IQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYES 180
Query: 181 ELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGD 240
ELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGD
Sbjct: 181 ELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGD 240
Query: 241 RLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQG 300
RLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQG
Sbjct: 241 RLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQG 300
Query: 301 CQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAE 360
CQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAE
Sbjct: 301 CQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAE 360
Query: 361 IRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSA 420
IRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSA
Sbjct: 361 IRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSA 420
Query: 421 YVICTVENCCL 431
YVICTVENCCL
Sbjct: 421 YVICTVENCCL 431
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 496 bits (1278), Expect = e-140
Identities = 259/426 (60%), Positives = 315/426 (73%), Gaps = 24/426 (5%)
Query: 5 CSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYF 64
C S CS S + S C P+ C T+C C C G LP
Sbjct: 34 CFSITCS--STMSYSCCLPSLGC--RTSCSSRPCVPPSCH------------GYTLP--- 74
Query: 65 TGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQ 124
G+CN P V NC W +G F +EKETMQFLNDRLASYLEKVR LE NAELE IQE+
Sbjct: 75 -GACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQER 133
Query: 125 CEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSL 184
+Q P++CP YQ YF TIE+LQQKILC KAEN+RL V +DN KLA+DDF+SKY++E SL
Sbjct: 134 SQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSL 193
Query: 185 RQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSV 244
R L+E+DI+S+ IL+ELTLCKSDLE+ VESL+E+L+CLKKNHEEEVN LR QLGDRL+V
Sbjct: 194 RLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNV 253
Query: 245 ELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQME 304
E+DTAPT+DLN+VL+E R Q E ++ NRRE E+W A QTEELN+Q +SS+EQLQ CQ E
Sbjct: 254 EVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAE 313
Query: 305 ILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCD 364
I+EL+RT +ALEIELQAQ +L +SLE T+ E+EA YSSQL+Q+Q LI N+E+QLAEIRCD
Sbjct: 314 IIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCD 373
Query: 365 LERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSAYVIC 424
LERQNQEYQVLLDV+ARLE EINTY LL+SED +L C+PC+TT S N+C PC
Sbjct: 374 LERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGT---- 429
Query: 425 TVENCC 430
+ + CC
Sbjct: 430 SQKGCC 435
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 495 bits (1275), Expect = e-140
Identities = 259/438 (59%), Positives = 321/438 (73%), Gaps = 20/438 (4%)
Query: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLL 60
M S C S S + G AS S + + ++S C+ PS +R + C +
Sbjct: 1 MASKCLKAGFSSGSLKSPGG---ASGGSTRVSAM---YSSSSCKLPSLSPVARSFSACSV 54
Query: 61 PCYFTGSCNSPCLVGNC--------------AWCEDGVFTSNEKETMQFLNDRLASYLEK 106
+ + CL C W +G+ T NEKETMQ LNDRLA YLEK
Sbjct: 55 GLGRSSYRATSCLPALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEK 114
Query: 107 VRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDN 166
VR LE+ NA LESRI+E CEQ +P +CPDYQ YF TIE+LQ+K LC+KAEN+RL V++DN
Sbjct: 115 VRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174
Query: 167 CKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKN 226
KLA DDF++KYE+E+SLRQL+E+DI+ L IL++LTLCKSDLEA VESLKE+LLCLKKN
Sbjct: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234
Query: 227 HEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEE 286
HEEEVN LR QLGDRL+VE+D AP +DLNRVL+EMRCQ ET++ NNRR+AE+WL Q+EE
Sbjct: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294
Query: 287 LNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQ 346
LNQQ +SS+EQLQ CQ EI+EL+RT +ALEIELQAQ S+ ++LE T+AETEA+YSSQLAQ
Sbjct: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354
Query: 347 IQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCS 406
+QC+I N+E QLAEIR DLERQNQEYQVLLDV+ARLE EINTY GLL+SEDS+L C+PC+
Sbjct: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCA 414
Query: 407 TTCTSSNTCEPCSAYVIC 424
+ S +C PC C
Sbjct: 415 PDYSPSKSCLPCLPAASC 432
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 495 bits (1274), Expect = e-140
Identities = 259/416 (62%), Positives = 310/416 (74%), Gaps = 5/416 (1%)
Query: 15 CGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLV 74
CGTA G + SS +C + A + S S GL CL Y + C++ V
Sbjct: 19 CGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFV 78
Query: 75 GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP 134
G+ W +G F +EKETMQFLNDRLA+YLEKVR LE NAELESRIQE E IP +CP
Sbjct: 79 GSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP 138
Query: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194
DYQ YF TIED QQKIL TK+EN+RL +Q+DN KLA DDF++KYE+ELSLRQL+EADI+
Sbjct: 139 DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADING 198
Query: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254
L IL+ELTLCK+DLEA VESLKE+L+CLKKNHEEEV++LR QLGDRL+VE+D AP +DL
Sbjct: 199 LRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDL 258
Query: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314
N++L++MRCQ E ++ NNRR+ E W QTEELNQQ +SS+EQLQ CQ EI+EL+RT +A
Sbjct: 259 NKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNA 318
Query: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374
LEIELQAQ S+ SLE T+AETEA+YSSQLAQ+QCLI N+E QL+EIRCDLERQNQEYQV
Sbjct: 319 LEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQV 378
Query: 375 LLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTC-----TSSNTCEPCSAYVICT 425
LLDVKARLEGEI TY LL+ ED +L PC+T C S PC V CT
Sbjct: 379 LLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCT 434
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 478 bits (1231), Expect = e-135
Identities = 248/398 (62%), Positives = 300/398 (75%), Gaps = 18/398 (4%)
Query: 21 CAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWC 80
C P+ SC T+C C C + C LP G+CN P V NC W
Sbjct: 6 CLPSLSC--RTSCSSRPCVPPSCHS------------CTLP----GACNIPANVSNCNWF 47
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYF 140
+G F +EKETMQFLNDRLASYLEKVR LE NAELE+ I+E+ +Q P++CP YQ YF
Sbjct: 48 CEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYF 107
Query: 141 NTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILE 200
TIE+LQQKILCTK+EN+RL VQ+DN KLA DDF++KY++ELSLRQL+E+DI+ L IL+
Sbjct: 108 KTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILD 167
Query: 201 ELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDE 260
ELTLCKSDLEA VESLKE+LLCLK NHE+EVN LR QLGDRL+VE+D APT+DLNRVL+E
Sbjct: 168 ELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNE 227
Query: 261 MRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQ 320
R Q E ++ NRRE E+W QTEELN+Q +SS+EQLQ Q EI+EL+RT +ALEIELQ
Sbjct: 228 TRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQ 287
Query: 321 AQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKA 380
AQ +L +SLE T+ E+EA+YSSQL+Q+Q LI N+E+QLAEIR DLERQNQEYQVLLDV+A
Sbjct: 288 AQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRA 347
Query: 381 RLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPC 418
RLE EINTY LL+SED L +PC+TT S PC
Sbjct: 348 RLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPC 385
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 476 bits (1224), Expect = e-134
Identities = 245/393 (62%), Positives = 304/393 (77%), Gaps = 11/393 (2%)
Query: 26 SCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVF 85
SC + + +C++ C PS GC LP G+CN P V NC W +G F
Sbjct: 4 SCGLPSLSCRTSCSSRPCVPPS-------CHGCTLP----GACNIPANVSNCNWFCEGSF 52
Query: 86 TSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIED 145
+EKETMQFLNDRLASYLEKVR LE NAELE+ I+E+ +Q P+VC YQ YF TIE+
Sbjct: 53 NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEE 112
Query: 146 LQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLC 205
LQQKILC+K+EN+RL VQ+DN KLA+DDF++KYE+ELSLRQL+E+DI+ L IL+ELTLC
Sbjct: 113 LQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLC 172
Query: 206 KSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQC 265
+SDLEA VESLKE+LLCLK+NHE+EVN LR QLGDRL+VE+D APT+DLN+VL+E R Q
Sbjct: 173 RSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQY 232
Query: 266 ETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSL 325
E ++ NRRE E+W A QTEELN+Q +SS+EQLQ Q EI+EL+RT +ALEIELQAQ +L
Sbjct: 233 EALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNL 292
Query: 326 TESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGE 385
+SLE T+ E+EA+YSSQL+Q+Q LI N+E+QLAEIR DLERQNQEYQVLLDV+ARLE E
Sbjct: 293 RDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECE 352
Query: 386 INTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPC 418
INTY LL+SED +L +PC+TT + PC
Sbjct: 353 INTYRSLLESEDCKLPSNPCATTNACDKSTGPC 385
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 473 bits (1217), Expect = e-133
Identities = 250/436 (57%), Positives = 312/436 (71%), Gaps = 17/436 (3%)
Query: 1 MTSDCSSTH---CSPESCGT-ASGCAPASSCSVETA----CLPGTCATSRCQTPSFLSRS 52
MTS C T+ S +SC AS C+ +C E C P C S C +F S
Sbjct: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS 60
Query: 53 RGLTGCLLPCYFTGSCNSPCLV----GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVR 108
CL Y + SC + + G +W +G F NEKETMQFLNDRLASYL +VR
Sbjct: 61 -----CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVR 115
Query: 109 SLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCK 168
LE+ NAELESRIQE + + PDYQ +F TIE+LQQKILCTKAEN+R+ V +DN K
Sbjct: 116 QLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAK 175
Query: 169 LATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHE 228
LA DDF++KYE+EL++RQL+EADI+ L IL++LTLCK+DLEA VESLKE+L+CLKKNHE
Sbjct: 176 LAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHE 235
Query: 229 EEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELN 288
EEV LR QLGDRL++E+D AP +DL RVL+EMRCQ E ++ NRR+ EEW +Q EELN
Sbjct: 236 EEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELN 295
Query: 289 QQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQ 348
QQ +S+EQLQ Q +I++L+RT + LEIELQAQ SL +SLE T+ E+EA+YSSQLAQ+Q
Sbjct: 296 QQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQ 355
Query: 349 CLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTT 408
C+I N+E QLAEIR DLERQNQEYQVLLDV+ARLEGEINTY LL++ED +L C+PCST
Sbjct: 356 CMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTP 415
Query: 409 CTSSNTCEPCSAYVIC 424
++ PC +C
Sbjct: 416 SCTTCVPSPCVPRTVC 431
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 462 bits (1190), Expect = e-130
Identities = 244/415 (58%), Positives = 303/415 (73%), Gaps = 32/415 (7%)
Query: 21 CAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWC 80
C P+ SC T+C C C G LP G+CN P V NC W
Sbjct: 6 CLPSLSC--RTSCSSRPCVPPSCH------------GYTLP----GACNIPANVSNCNWF 47
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYF 140
+G F +EKETMQFLNDRLASYLEKVR LE NAELE+ I+E+ +Q P++CP YQ YF
Sbjct: 48 CEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYF 107
Query: 141 NTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILE 200
TIE+LQQKILC+K+EN+RL VQ+DN KLA DDF++KY++E SLRQL+E+DI+SL IL+
Sbjct: 108 KTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILD 167
Query: 201 ELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDE 260
ELTLC+SDLEA +ESLKE+LL LK+NHE+EVN LR QLGDRL+VE+D AP +DLN+VL+E
Sbjct: 168 ELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNE 227
Query: 261 MRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQ 320
R Q E ++ NRRE E+W A QTEELN+Q +SS+EQLQ Q EI+EL+RT +ALEIELQ
Sbjct: 228 TRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQ 287
Query: 321 AQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKA 380
AQ +L SLE T+ E+EA+YSSQL+Q+Q LI N+E+QLAEIR DLERQNQEYQVLLDV+A
Sbjct: 288 AQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRA 347
Query: 381 RLEGEINTYWGLLDSEDSRLSCSPCSTT--------------CTSSNTCEPCSAY 421
RLE EINTY LL+SED +L +PC+TT C + C PC+ +
Sbjct: 348 RLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTNPCGPRSRCGPCNTF 402
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 433 bits (1114), Expect = e-121
Identities = 224/447 (50%), Positives = 300/447 (67%), Gaps = 19/447 (4%)
Query: 2 TSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCL-- 59
T C++T+ C S S+ S C PG + CQ + R GC
Sbjct: 3 TKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPT 62
Query: 60 -----LPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETN 114
P Y + N+ + +C+W +G+ SNEKETMQ LN+RLA+YL+KVR LE N
Sbjct: 63 PRFCRKPIYLMNNFNARFSLDDCSWYGEGI-NSNEKETMQILNERLANYLQKVRMLEREN 121
Query: 115 AELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDF 174
AELES+IQE+ +++P++CPDY Y+ TIE+LQQKILCTKAENSRL Q+DN KL DD
Sbjct: 122 AELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDL 181
Query: 175 KSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLL 234
++KYE+E+SLRQL+E+D + L IL LTL K+DLEA V+SLKE+LLCLK NH+EE+N L
Sbjct: 182 RAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSL 241
Query: 235 REQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSS 294
+ QLG+RL +E+ AP+ DLN+VL EMRCQ E ++ NR++ E+W Q EELNQQ ++S
Sbjct: 242 QCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTS 301
Query: 295 AEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNL 354
++Q Q CQ EI+EL+R+ + LE+ELQAQ + +S EC + ETEA+Y++ L QIQ LIDNL
Sbjct: 302 SQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNL 361
Query: 355 ENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSS-- 412
E QLAEIRC LERQNQEY++LLDVK+RLE EI TY LL+S D + C P +T C S
Sbjct: 362 EAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPW 421
Query: 413 ---------NTCEPCSAYVICTVENCC 430
+T C++ C+++ C
Sbjct: 422 TSCKSGAIESTAPACTSSSPCSLKEHC 448
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 413 bits (1061), Expect = e-115
Identities = 225/442 (50%), Positives = 290/442 (65%), Gaps = 24/442 (5%)
Query: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCAT--SRCQTPSFLSRSRGLTG- 57
MTS SS+ C P C A G S ++ C PG A C + +R G
Sbjct: 1 MTSSYSSSSC-PLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGS 59
Query: 58 --------CLLP-----CYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYL 104
CL P C G+C+ P +G C + +EKETMQFLNDRLA+YL
Sbjct: 60 TPLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYL 119
Query: 105 EKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQL 164
EKVR LE+ NAELE+ + E+ + VCPDYQ YF+TIE+LQQKILC+KAEN+RL VQ+
Sbjct: 120 EKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQI 179
Query: 165 DNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLK 224
DN KLA DDF+ K ESE SLRQL+EAD +L++ TL K+DLEA ESLKE+ L LK
Sbjct: 180 DNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLK 239
Query: 225 KNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQT 284
NHE+EV +LR QLG++L +ELD PT+DLNRVL EMR Q E +L NR++ E+W Q+
Sbjct: 240 SNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQS 299
Query: 285 EELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQL 344
E ++ Q +S +E+LQ CQ EILEL+ T +ALE+E QAQ +L + L+ ++ E E ++ ++L
Sbjct: 300 EGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTEL 359
Query: 345 AQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSP 404
AQ+Q LI N+E QL+EIR DLERQNQEYQVLLDVK RLE EI TY LL+SED +L C+P
Sbjct: 360 AQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNP 419
Query: 405 CSTT-------CTSSNTCEPCS 419
CST+ C +C PC+
Sbjct: 420 CSTSPSCVTAPCAPRPSCGPCT 441
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 404 bits (1038), Expect = e-113
Identities = 222/435 (51%), Positives = 285/435 (65%), Gaps = 19/435 (4%)
Query: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLP--GTCATSRCQTPSFLSRSRGLTG- 57
MTS S++ C P C A G ++ C P A S C + +R G
Sbjct: 1 MTSFYSTSSC-PLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGS 59
Query: 58 --------CLLP-----CYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYL 104
CL P C G+C+ P +G C +EKETM+FLNDRLA+YL
Sbjct: 60 TPLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYL 119
Query: 105 EKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQL 164
EKVR LE+ NAELE+ + E+ + VCPDYQ YF TIE+LQQKILC+KAEN+RL VQ+
Sbjct: 120 EKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQI 179
Query: 165 DNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLK 224
DN KLA DDF+ K ESE SL QL+EAD +L++ TL K+DLEA ESLKE+ L LK
Sbjct: 180 DNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLK 239
Query: 225 KNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQT 284
NHE+EV +LR QLG++ +ELD PT+DLNRVL EMR Q E ++ N ++ E+W Q+
Sbjct: 240 SNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQS 299
Query: 285 EELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQL 344
E ++ Q +S +E+LQ CQ EILEL+ T +ALE+E QAQ +L + L+ ++ E E +Y ++L
Sbjct: 300 EGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTEL 359
Query: 345 AQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSP 404
AQ+Q LI NLE QL+EIR DLERQNQEYQVLLDVKARLE EI TY LL+SED +L C+P
Sbjct: 360 AQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNP 419
Query: 405 CST--TCTSSNTCEP 417
CST +CTS +C P
Sbjct: 420 CSTPASCTSCPSCGP 434
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 343 bits (879), Expect = 2e-94
Identities = 176/331 (53%), Positives = 245/331 (74%)
Query: 82 DGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFN 141
DG+ +EK TMQ LNDRLASYL+KVR+LEE NA+LE +I++ ++ P DY YF
Sbjct: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167
Query: 142 TIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEE 201
TIEDL+ KIL +N+ + +Q+DN +LA DDF++KYE+EL+LR +EADI+ L +L+E
Sbjct: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227
Query: 202 LTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEM 261
LTL ++DLE +ESLKE+L LKKNHEEE+N LR Q+G ++VE+D AP +DL+R+L+EM
Sbjct: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287
Query: 262 RCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQA 321
R Q E + NR++AEEW +TEELN++ +++E +Q + EI EL+RT LEIELQ+
Sbjct: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347
Query: 322 QQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKAR 381
Q S+ SLE ++ ET+ +Y QLAQIQ +I ++E QLA++RC++E+QNQEY++LLDVK R
Sbjct: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407
Query: 382 LEGEINTYWGLLDSEDSRLSCSPCSTTCTSS 412
LE EI TY LL+ ED+ LS S S+ SS
Sbjct: 408 LEQEIATYRRLLEGEDAHLSSSQFSSGSQSS 438
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 338 bits (866), Expect = 7e-93
Identities = 185/390 (47%), Positives = 260/390 (66%), Gaps = 5/390 (1%)
Query: 14 SCGTASGCAPASSCSVETAC-LPGTCATSRCQTPSFLSRSRGLTGCLLP-CYFTGSCNSP 71
S + G + S T+C L G C+ S L G CY GS
Sbjct: 10 SSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGG- 68
Query: 72 CLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPM 131
G+ DG+ EK TMQ LNDRLASYL+KVR+LEE N ELE +I++ ++ P
Sbjct: 69 --YGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPG 126
Query: 132 VCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEAD 191
DY +Y+ TIE+LQ KIL +N+ + +Q+DN +LA DDF++K+E+E +LR +EAD
Sbjct: 127 PARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEAD 186
Query: 192 ISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPT 251
I+ L +L+ELTL ++DLE +E+LKE+L LKKNHEEE+N LR Q+G ++VE+D AP
Sbjct: 187 INGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPG 246
Query: 252 LDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRT 311
+DL+R+L+EMR Q E + NR++AE+W +TEELN++ +++E +Q + EI EL+RT
Sbjct: 247 VDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRT 306
Query: 312 ASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQE 371
ALEIELQ+Q S+ SLE +AETE +Y QL+QIQ LI ++E QLA++RC++E+QNQE
Sbjct: 307 MQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQE 366
Query: 372 YQVLLDVKARLEGEINTYWGLLDSEDSRLS 401
Y++LLDVK RLE EI TY LL+ ED+ L+
Sbjct: 367 YKILLDVKTRLEQEIATYRRLLEGEDAHLT 396
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 333 bits (854), Expect = 2e-91
Identities = 171/331 (51%), Positives = 238/331 (71%)
Query: 82 DGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFN 141
DG+ +EK TMQ LNDRLASYL+KVR+LEE NA+LE +I++ ++ P DY YF
Sbjct: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
Query: 142 TIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEE 201
TIEDL+ KI+ EN++ +Q+DN +LA DDF++KYE EL+LRQ +EAD++ L +L+E
Sbjct: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
Query: 202 LTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEM 261
LTL ++DLE +E LKE+L L+KNHEEE+ LR Q G ++VE+D AP +DL+R+L+EM
Sbjct: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
Query: 262 RCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQA 321
R Q E + NRR+AE W +TEELN++ S++E +Q + E+ EL+R LEIELQ+
Sbjct: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
Query: 322 QQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKAR 381
Q S+ SLE ++ ET+ +Y QL+QIQ LI ++E QLA++RC++E+Q+QEYQ+LLDVK R
Sbjct: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
Query: 382 LEGEINTYWGLLDSEDSRLSCSPCSTTCTSS 412
LE EI TY LL+ ED+ LS S SS
Sbjct: 410 LEQEIATYRRLLEGEDAHLSSQQASGQSYSS 440
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 326 bits (836), Expect = 2e-89
Identities = 165/323 (51%), Positives = 229/323 (70%)
Query: 75 GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP 134
G DG+ NEK TMQ LNDRLASYL+KVR+LE N ELE +I++ ++ P
Sbjct: 66 GGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSR 125
Query: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194
DY Y+ TI+DL+ KIL ENSR+ +Q+DN +LA DDF++K+E+E +LR +EADI+
Sbjct: 126 DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADING 185
Query: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254
L +L+ELTL ++DLE +E LKE+L LKKNHEEE++ LR Q+G ++SVE+D+AP DL
Sbjct: 186 LRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDL 245
Query: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314
++L +MR Q E + NR++AE W +TEELN++ EQLQ + E+ +L+RT
Sbjct: 246 AKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQG 305
Query: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374
LEIELQ+Q S+ +LE T+AETEA++ +QLA IQ LI +E QL ++R D ERQNQEYQ
Sbjct: 306 LEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQR 365
Query: 375 LLDVKARLEGEINTYWGLLDSED 397
L+D+K+RLE EI TY LL+ ++
Sbjct: 366 LMDIKSRLEQEIATYRSLLEGQE 388
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 323 bits (829), Expect = 1e-88
Identities = 166/322 (51%), Positives = 233/322 (72%), Gaps = 1/322 (0%)
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP-DYQRY 139
+ G+ + NEK TMQ LNDRLASYL+KVR+LEE NA+LE +I + ++ P DY +Y
Sbjct: 97 DGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQY 156
Query: 140 FNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGIL 199
F TIE+L+ KI+ T +NSR+ +++DN +LA DDF+ KYE+EL+LRQ +EADI+ L +L
Sbjct: 157 FKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVL 216
Query: 200 EELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLD 259
+ELTL ++DLE +E L E+L LKKNHEEE+ QL +++VE+D AP +DL RVL
Sbjct: 217 DELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLA 276
Query: 260 EMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIEL 319
EMR Q E + NRR+ E W +TEELN++ S+ E +Q + EI +L+RT LEIEL
Sbjct: 277 EMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIEL 336
Query: 320 QAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVK 379
Q+Q S+ LE ++AETE +Y++QL QIQ LI LE QL+E+RC++E QNQEY++LLD+K
Sbjct: 337 QSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIK 396
Query: 380 ARLEGEINTYWGLLDSEDSRLS 401
RLE EI TY LL+ +D++++
Sbjct: 397 TRLEQEIATYRSLLEGQDAKMA 418
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 322 bits (824), Expect = 5e-88
Identities = 172/344 (50%), Positives = 241/344 (70%), Gaps = 9/344 (2%)
Query: 80 CEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQE-QCEQDIPMVCPDYQR 138
C+ G+ T NEK TMQ LNDRLASYLEKVR+LEE NA+LE +I++ +Q DY
Sbjct: 95 CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
Query: 139 YFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGI 198
Y+ TIE+L+ KIL EN+R+ +++DN +LA DDF+ KYE+EL+LRQ +EADI+ L +
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
Query: 199 LEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVL 258
L+ELTL K+DLE +ESL E+L +KKNHEEE+ Q+ +++VE+D P +DL RVL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
Query: 259 DEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIE 318
EMR Q E + NRR+AEEW ++ ELN++ ++ +Q + EI EL+RT LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
Query: 319 LQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDV 378
LQ+Q S+ LE TVAETE +Y+ QL QIQ LI ++E QL+E+R ++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
Query: 379 KARLEGEINTYWGLLDSEDSRL--------SCSPCSTTCTSSNT 414
K RLE EI TY LL+ +D+++ S SP ST+ T++++
Sbjct: 395 KTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSS 438
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 317 bits (812), Expect = 1e-86
Identities = 166/321 (51%), Positives = 229/321 (71%), Gaps = 1/321 (0%)
Query: 80 CEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQE-QCEQDIPMVCPDYQR 138
C+ G+ T NEK TMQ LNDRLASYLEKVR+LEE NA+LE +I++ +Q DY
Sbjct: 95 CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154
Query: 139 YFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGI 198
Y+ TIE+L+ KIL EN+R+ +++DN +LA DDF+ KYE+EL+LRQ +EADI+ L +
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214
Query: 199 LEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVL 258
L+ELTL K+DLE +ESL E+L +KKNHEEE+ Q+ +++VE+D P +DL RVL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274
Query: 259 DEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIE 318
EMR Q E + NRR+AEEW ++ ELN++ ++ +Q + EI EL+RT LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334
Query: 319 LQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDV 378
LQ+Q S+ LE TVAETE +Y+ QL QIQ LI ++E QL+E+R ++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394
Query: 379 KARLEGEINTYWGLLDSEDSR 399
K RLE EI TY LL+ +D++
Sbjct: 395 KTRLEQEIATYRSLLEGQDAK 415
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 297 bits (760), Expect = 1e-80
Identities = 157/320 (49%), Positives = 223/320 (69%), Gaps = 4/320 (1%)
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQ----DIPMVCPDY 136
+ G+ + +EKETMQ LNDRLASYL+KVR+LEE N ELE++I+E E DY
Sbjct: 117 DGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDY 176
Query: 137 QRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLH 196
+Y+ IEDL+ KI+ N++L +Q+DN +LA +DF+ KYE+EL+LRQ +EADI+ L
Sbjct: 177 SKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLR 236
Query: 197 GILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNR 256
+L+ELTL ++DLE +ESL E+L +KKNHE+E+ R +SVE+D AP +DL R
Sbjct: 237 RVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTR 296
Query: 257 VLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALE 316
+L++MR Q ET+ NR++AE W ++ EL ++ ++ EQLQ + E+ +L+R LE
Sbjct: 297 LLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLE 356
Query: 317 IELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLL 376
IELQ+Q ++ +SLE ++AE E Y +QL+Q+Q LI NLE QL ++R D ERQN ++Q LL
Sbjct: 357 IELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLL 416
Query: 377 DVKARLEGEINTYWGLLDSE 396
+VKARLE EI TY LLD E
Sbjct: 417 NVKARLELEIETYRRLLDGE 436
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 295 bits (754), Expect = 7e-80
Identities = 160/324 (49%), Positives = 222/324 (68%), Gaps = 9/324 (2%)
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCE------QDIPMVCP 134
+ G+ + NEK TMQ LNDRLASYL+KVR+LEE+N ELE +I+E E Q P
Sbjct: 138 DGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR--- 194
Query: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194
DY +Y+ TI+DL+ +IL +N+ + +Q+DN +LA DDF+ KYE+E++LRQ +EADI+
Sbjct: 195 DYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADING 254
Query: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254
L +L+ELTL K+DLE +ESL E+L LKKNHEEE+ LR ++VE++ AP +DL
Sbjct: 255 LRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDL 314
Query: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314
++L+ MR Q E + NR++AE W +++EL + ++ EQ+ + EI EL+R A
Sbjct: 315 TQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQA 374
Query: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374
LEIELQ+Q +L +SLE ++AETE +Y QL+QIQ I LE QL +IR + E QN EYQ
Sbjct: 375 LEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQ 434
Query: 375 LLDVKARLEGEINTYWGLLDSEDS 398
LLD+K RLE EI TY LL+ E S
Sbjct: 435 LLDIKIRLENEIQTYRSLLEGEGS 458
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 294 bits (752), Expect = 1e-79
Identities = 153/324 (47%), Positives = 226/324 (69%)
Query: 84 VFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTI 143
+F NEK MQ LNDRLASYLEKVR+LE++N++LE +I++ E + P DY Y+ I
Sbjct: 65 LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQI 124
Query: 144 EDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELT 203
E+L+ +I + +N+R +Q+DN KLA +DF+ KYE+E +R +EAD+ L+ + ++LT
Sbjct: 125 EELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLT 184
Query: 204 LCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRC 263
L K+DLE +E L +DL LKK H+EEV+ L + LG+ ++VE+D AP L+L +++EMR
Sbjct: 185 LHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQ 244
Query: 264 QCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQ 323
+ E + N +EA+E QT L QQ + E+L+G ++++ EL+RT+ +LEIELQ+
Sbjct: 245 KYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHL 304
Query: 324 SLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLE 383
S+ ESLE T+ ET+A+YSSQLA +Q L+ +LE QL +IR ++ERQN EY +LLD+K RLE
Sbjct: 305 SMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLE 364
Query: 384 GEINTYWGLLDSEDSRLSCSPCST 407
EI TY LL+ ED + + ST
Sbjct: 365 QEIATYRRLLEGEDVKTTEYQLST 388
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 286 bits (732), Expect = 3e-77
Identities = 161/358 (44%), Positives = 222/358 (62%), Gaps = 13/358 (3%)
Query: 66 GSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQC 125
GS + GN E G+ + NEK TMQ LNDRLASYLE VR+LEE NA+LE +I+
Sbjct: 65 GSASCAAFTGN----EHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120
Query: 126 EQDIPMVCP----DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESE 181
E+ P C DY RYF I++L+ +I+ N+ + +Q DN +L DDF+ K+E+E
Sbjct: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180
Query: 182 LSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDR 241
L+L Q +EADI+ L +L+ELTLC++DLE +E+L E+L LKKNHEEE+ L+ G
Sbjct: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240
Query: 242 LSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGC 301
++VE++ AP +DL +L+ MR + E + NRR+AE W ++ L QQ A
Sbjct: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300
Query: 302 QMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEI 361
+ E++E+KRT LEIELQ+ + SLEC++ ETE+ Y +QLAQIQ I LE QL ++
Sbjct: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360
Query: 362 RCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCS-----PCSTTCTSSNT 414
R + E Q EY+ LLD+K LE EI TY L+D ED S S P + T SS T
Sbjct: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSCSKSKGYGGPGNQTKDSSKT 418
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 278 bits (712), Expect = 5e-75
Identities = 154/339 (45%), Positives = 217/339 (64%), Gaps = 8/339 (2%)
Query: 69 NSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQD 128
N+ C+ A E G+ + NEK TMQ LNDRLASYL+ VR+LEE NAELE +I+ E+
Sbjct: 68 NAACI--GFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKY 125
Query: 129 IPMVCP----DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSL 184
P C DY RY TIEDL+ KI+ + N+ + +Q+DN +LA DDF+ KYE+EL+L
Sbjct: 126 GPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTL 185
Query: 185 RQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSV 244
Q +EADI+ L +L+ELTLC++D E ESL E++ LKKNHEEE+ L+ G ++V
Sbjct: 186 HQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNV 245
Query: 245 ELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQME 304
E++ AP +DL +L+ MR + E + NR++AE W ++ L QQ + + +
Sbjct: 246 EMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQ 305
Query: 305 ILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCD 364
+ E++RT LEI+LQ+ + SLEC++ ETE+ Y +QLAQIQ I LE QL ++R +
Sbjct: 306 LTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTE 365
Query: 365 LERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCS 403
E Q EY+ LLDVK LE EI TY L+D + + SCS
Sbjct: 366 TEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGN--SCS 402
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 276 bits (705), Expect = 3e-74
Identities = 149/321 (46%), Positives = 215/321 (66%), Gaps = 5/321 (1%)
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP-----D 135
+ G+F+ EK+TMQ LNDRLA+YL+KVR+LEE N +LE++I+E ++ P D
Sbjct: 132 DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRD 191
Query: 136 YQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSL 195
Y +Y++ IEDL+ +I+ EN+ + + +DN +LA DDF+ KYE+EL LRQ +EADI+ L
Sbjct: 192 YSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGL 251
Query: 196 HGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLN 255
+L++LT+ +SDLE +ES E+L L+KNHEEE+ ++ G ++VE++ AP DL
Sbjct: 252 RKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLT 311
Query: 256 RVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASAL 315
++L++MR Q E + NRREAEE Q+ L Q + A + EI ELKRT AL
Sbjct: 312 KLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQAL 371
Query: 316 EIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVL 375
EIELQ+Q ++ SLE T+A+TEA Y +QL++IQ I LE ++ +I + + QN EY+ L
Sbjct: 372 EIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQL 431
Query: 376 LDVKARLEGEINTYWGLLDSE 396
LD+K RLE EI TY LLD E
Sbjct: 432 LDIKTRLEVEIETYRRLLDGE 452
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 273 bits (698), Expect = 2e-73
Identities = 143/321 (44%), Positives = 206/321 (64%), Gaps = 4/321 (1%)
Query: 81 EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP----DY 136
E G+ + NEK TMQ LNDRLASYL+ V +LEE NA+LE +I+ E+ P C DY
Sbjct: 71 ERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDY 130
Query: 137 QRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLH 196
RYF I+DL+ +I+ + N+ +Q+DN +L DDF+ KYE+EL+L Q +EAD++ L
Sbjct: 131 SRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLR 190
Query: 197 GILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNR 256
+L+E+TLC++DLE E+L E++ LKKNH+EE+ +L+ G ++VE++ AP +DL
Sbjct: 191 RVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTV 250
Query: 257 VLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALE 316
+L+ MR + E + NRR+AE W ++ L QQ + E+ E+KRT LE
Sbjct: 251 LLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLE 310
Query: 317 IELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLL 376
IELQ+ + SLEC++ ETE+ Y +QLAQIQ I LE QL ++R + E Q EY+ LL
Sbjct: 311 IELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLL 370
Query: 377 DVKARLEGEINTYWGLLDSED 397
D+K LE EI TY L+ +D
Sbjct: 371 DIKLHLEKEIETYCLLIGGDD 391
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 263 bits (671), Expect = 3e-70
Identities = 158/382 (41%), Positives = 222/382 (58%), Gaps = 16/382 (4%)
Query: 50 SRSRGLTGCLLPCYFTGS--CNSPCLVGNCAWC-----EDGVFTSNEKETMQFLNDRLAS 102
S +R C L +G CNS +G+ A E + + NEK TMQ LNDRLAS
Sbjct: 37 SGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLAS 96
Query: 103 YLEKVRSLEETNAELESRIQ---EQCEQDIPMVCP-DYQRYFNTIEDLQQKILCTKAENS 158
YL+ V +LEE NA+LE +I+ E+CE DY RYF+ IEDL+++I N+
Sbjct: 97 YLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNA 156
Query: 159 RLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKE 218
+ +Q DN +L DDF+ KYE+EL+L +EAD S L +L+ELTLC +DLE E+L E
Sbjct: 157 SIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSE 216
Query: 219 DLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEE 278
+L LKK+HEEE+ +L+ G ++VE++ P +DL +L+ MR + E + NR++AE
Sbjct: 217 ELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEA 276
Query: 279 WLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEA 338
W ++ L QQ + E+ ELKR LEIELQ+ ++ S EC++AETE
Sbjct: 277 WFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEG 336
Query: 339 QYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDS 398
Y +QL QIQ I +E QL +IR + E Q EY+ LLDVK LE EI+ Y LLD E+
Sbjct: 337 NYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEER 396
Query: 399 RLSCSPCSTTCTSSNTCEPCSA 420
+ +TC S P ++
Sbjct: 397 K-----SKSTCYKSKGYRPVNS 413
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 254 bits (648), Expect = 1e-67
Identities = 133/321 (41%), Positives = 210/321 (65%), Gaps = 1/321 (0%)
Query: 75 GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPM-VC 133
G + G+ T+NEK TMQ LN RLASYL+KV++LEE N +LE++IQ+ ++ P +
Sbjct: 139 GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQ 198
Query: 134 PDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADIS 193
+Y Y+NTI+DL+ +I+ N++ + +DN ++ DDF+ K+E E +LRQ ++ADI+
Sbjct: 199 KNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADIN 258
Query: 194 SLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLD 253
L +L+ LT+ KSDLE E+L+E+L+ LKKNH+EE++ L Q ++VE++ AP D
Sbjct: 259 GLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKD 318
Query: 254 LNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTAS 313
L + L++MR + E ++A NR++ E Q ++ + SS +++Q E+ +L+
Sbjct: 319 LTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQ 378
Query: 314 ALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQ 373
LEIELQ+Q S +LE ++ +T+ +Y QL IQ I NLE Q+ ++R ++E QNQEY
Sbjct: 379 ELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYS 438
Query: 374 VLLDVKARLEGEINTYWGLLD 394
+LL +K RLE EI TY LL+
Sbjct: 439 LLLSIKMRLEKEIETYHNLLE 459
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 252 bits (644), Expect = 4e-67
Identities = 134/315 (42%), Positives = 209/315 (66%), Gaps = 3/315 (0%)
Query: 88 NEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQ 147
NEKETMQ LNDRLASYL++VRSLE N LES+I+E E+ P V D+ YF IEDL+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 148 QKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKS 207
+I +N+R+ +Q+DN +LA DDF+ KYE+EL++RQ +E DI L ++++ + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 208 DLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDR-LSVELDTAPTLDLNRVLDEMRCQCE 266
LE +E+LKE+LL +KKNHEEEV L+ Q+ L+VE+D + DL +++ ++R Q +
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 267 TVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLT 326
+ NR E +++ + Q EE + + ++ + + EL+RT +LEI+L + ++L
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 327 ESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEI 386
SLE ++ E EA+Y+ Q+ Q+ ++ +LE++LA+ R + +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 387 NTYWGLL-DSEDSRL 400
TY LL D ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 252 bits (644), Expect = 4e-67
Identities = 134/315 (42%), Positives = 209/315 (66%), Gaps = 3/315 (0%)
Query: 88 NEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQ 147
NEKETMQ LNDRLASYL++VRSLE N LES+I+E E+ P V D+ YF IEDL+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 148 QKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKS 207
+I +N+R+ +Q+DN +LA DDF+ KYE+EL++RQ +E DI L ++++ + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 208 DLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDR-LSVELDTAPTLDLNRVLDEMRCQCE 266
LE +E+LKE+LL +KKNHEEEV L+ Q+ L+VE+D + DL +++ ++R Q +
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 267 TVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLT 326
+ NR E +++ + Q EE + + ++ + + EL+RT +LEI+L + ++L
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 327 ESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEI 386
SLE ++ E EA+Y+ Q+ Q+ ++ +LE++LA+ R + +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 387 NTYWGLL-DSEDSRL 400
TY LL D ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 240 bits (613), Expect = 2e-63
Identities = 132/309 (42%), Positives = 199/309 (64%), Gaps = 1/309 (0%)
Query: 88 NEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQ 147
N K TMQ LNDRLASYLEKVR+LEE N +LESRI + +Q P DY +Y I LQ
Sbjct: 71 NGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQ 130
Query: 148 QKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKS 207
++I+ K N+++ + +DN ++A DDF KYE+E S ++ LE ++ L L+ LT+ +
Sbjct: 131 EQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTT 190
Query: 208 DLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCET 267
DLE VE ++++L+ +KK+HE+E+ ++V++DT P DL +VL++MR + E
Sbjct: 191 DLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYEL 250
Query: 268 VLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTE 327
++ R+ + W Q+ ++Q+ S A +Q Q +I ELKRT ALEI+LQ Q S
Sbjct: 251 IIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTKS 309
Query: 328 SLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEIN 387
+LE ++ET+++YS +L +Q +I + E +L ++R +LERQN EYQVLL +K LE EI
Sbjct: 310 ALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEIT 369
Query: 388 TYWGLLDSE 396
TY LL+ E
Sbjct: 370 TYRRLLEGE 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,881,137
Number of Sequences: 37866
Number of extensions: 703291
Number of successful extensions: 7579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 230
Number of HSP's successfully gapped in prelim test: 530
Number of HSP's that attempted gapping in prelim test: 4013
Number of HSP's gapped (non-prelim): 2793
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.