Guide to the Human Genome
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Search of human proteins with 34335264

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
         (1135 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...  2288   0.0  
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...  2274   0.0  
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...  2255   0.0  
gi|238814389 zinc finger, MYND domain containing 11 isoform a [H...   186   1e-46
gi|238814385 zinc finger, MYND domain containing 11 isoform a [H...   186   1e-46
gi|238814387 zinc finger, MYND domain containing 11 isoform b [H...   182   2e-45
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    91   6e-18
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    91   6e-18
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    90   1e-17
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    81   6e-15
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    81   6e-15
gi|38788260 bromodomain PHD finger transcription factor isoform ...    75   5e-13
gi|38788274 bromodomain PHD finger transcription factor isoform ...    75   5e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     71   5e-12
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             70   9e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   69   3e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    69   3e-11
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]           68   4e-11
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]           68   4e-11
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa...    67   1e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   65   3e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   65   3e-10
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    64   8e-10
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    64   8e-10
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ...    63   1e-09
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ...    63   1e-09
gi|158420731 chromodomain helicase DNA binding protein 3 isoform...    63   1e-09
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    62   3e-09
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]             61   7e-09
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08

>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
            sapiens]
          Length = 1135

 Score = 2288 bits (5928), Expect = 0.0
 Identities = 1135/1135 (100%), Positives = 1135/1135 (100%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW 120
            PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW
Sbjct: 61   PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW 120

Query: 121  FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY 180
            FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY
Sbjct: 121  FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY 180

Query: 181  AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC 240
            AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC
Sbjct: 181  AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC 240

Query: 241  EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA 300
            EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA
Sbjct: 241  EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA 300

Query: 301  RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF 360
            RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF
Sbjct: 301  RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF 360

Query: 361  RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420
            RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS
Sbjct: 361  RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420

Query: 421  LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG 480
            LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG
Sbjct: 421  LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG 480

Query: 481  SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540
            SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL
Sbjct: 481  SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540

Query: 541  ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600
            ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD
Sbjct: 541  ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600

Query: 601  DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660
            DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD
Sbjct: 601  DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660

Query: 661  KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720
            KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE
Sbjct: 661  KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720

Query: 721  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780
            GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV
Sbjct: 721  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780

Query: 781  TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840
            TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ
Sbjct: 781  TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840

Query: 841  SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900
            SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN
Sbjct: 841  SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900

Query: 901  TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL 960
            TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL
Sbjct: 901  TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL 960

Query: 961  ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ 1020
            ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ
Sbjct: 961  ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ 1020

Query: 1021 EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS 1080
            EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS
Sbjct: 1021 EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS 1080

Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135
            SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
            sapiens]
          Length = 1160

 Score = 2274 bits (5892), Expect = 0.0
 Identities = 1135/1160 (97%), Positives = 1135/1160 (97%), Gaps = 25/1160 (2%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95
            PIKKKKKPGLLNSNNKEQ                         DGRNDFYCWVCHREGQV
Sbjct: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120

Query: 96   LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155
            LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180

Query: 156  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215
            AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240

Query: 216  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275
            LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300

Query: 276  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335
            VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360

Query: 336  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395
            SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420

Query: 396  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455
            FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480

Query: 456  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515
            ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540

Query: 516  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575
            DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600

Query: 576  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635
            YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660

Query: 636  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695
            PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720

Query: 696  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755
            VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780

Query: 756  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815
            PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840

Query: 816  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
            SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900

Query: 876  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935
            AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960

Query: 936  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995
            LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020

Query: 996  DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055
            DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080

Query: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1115
            KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1140

Query: 1116 TSTSTKSLLPKESRLDTFWD 1135
            TSTSTKSLLPKESRLDTFWD
Sbjct: 1141 TSTSTKSLLPKESRLDTFWD 1160


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
            sapiens]
          Length = 1188

 Score = 2255 bits (5844), Expect = 0.0
 Identities = 1134/1188 (95%), Positives = 1134/1188 (95%), Gaps = 53/1188 (4%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95
            PIKKKKKPGLLNSNNKEQ                         DGRNDFYCWVCHREGQV
Sbjct: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120

Query: 96   LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155
            LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180

Query: 156  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215
            AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240

Query: 216  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275
            LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300

Query: 276  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335
            VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360

Query: 336  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395
            SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420

Query: 396  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455
            FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480

Query: 456  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515
            ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540

Query: 516  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575
            DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600

Query: 576  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635
            YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660

Query: 636  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695
            PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720

Query: 696  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755
            VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780

Query: 756  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815
            PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840

Query: 816  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
            SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900

Query: 876  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935
            AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960

Query: 936  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995
            LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020

Query: 996  DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055
            DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080

Query: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS------------------------- 1090
            KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS                         
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140

Query: 1091 ---DHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135
                HSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188


>gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo
           sapiens]
          Length = 602

 Score =  186 bits (471), Expect = 1e-46
 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 22/275 (8%)

Query: 82  NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135
           +D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP C  I      +
Sbjct: 99  HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155

Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195
                      +++   L+F + +MK+   D  +K     +HP Y   +   +D+ T+++
Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203

Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255
              +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE++E+++C  C+ 
Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFY 263

Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314
            +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG  H RAW+P  
Sbjct: 264 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 323

Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349
           N   ++  I     K    +  A  E+E++   +R
Sbjct: 324 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)

Query: 816  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
            + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 401  NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460

Query: 876  AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927
                S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 461  GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513

Query: 928  SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 986
            ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQWC NC++EA++
Sbjct: 514  NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572

Query: 987  YCCWNTSYCDYPCQQAHW-PEHMKSC 1011
            +CCWNTSYC   CQQ HW  EH ++C
Sbjct: 573  HCCWNTSYCSIKCQQEHWHAEHKRTC 598


>gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo
           sapiens]
          Length = 602

 Score =  186 bits (471), Expect = 1e-46
 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 22/275 (8%)

Query: 82  NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135
           +D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP C  I      +
Sbjct: 99  HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155

Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195
                      +++   L+F + +MK+   D  +K     +HP Y   +   +D+ T+++
Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203

Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255
              +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE++E+++C  C+ 
Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFY 263

Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314
            +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG  H RAW+P  
Sbjct: 264 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 323

Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349
           N   ++  I     K    +  A  E+E++   +R
Sbjct: 324 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)

Query: 816  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
            + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 401  NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460

Query: 876  AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927
                S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 461  GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513

Query: 928  SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 986
            ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQWC NC++EA++
Sbjct: 514  NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572

Query: 987  YCCWNTSYCDYPCQQAHW-PEHMKSC 1011
            +CCWNTSYC   CQQ HW  EH ++C
Sbjct: 573  HCCWNTSYCSIKCQQEHWHAEHKRTC 598


>gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo
           sapiens]
          Length = 567

 Score =  182 bits (461), Expect = 2e-45
 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 23/275 (8%)

Query: 82  NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135
           +D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP C  I      +
Sbjct: 99  HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155

Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195
                      +++   L+F + +MK+   D  +K     +HP Y   +   +D+ T+++
Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203

Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255
              +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE++E+++C  C+ 
Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGDSEQ-ADIARMLYKDTCHELDELQLCKNCFY 262

Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314
            +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG  H RAW+P  
Sbjct: 263 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 322

Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349
           N   ++  I     K    +  A  E+E++   +R
Sbjct: 323 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 357



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 17/170 (10%)

Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
           + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 400 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 459

Query: 876 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927
               S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 460 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 512

Query: 928 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQW 976
           ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQW
Sbjct: 513 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQW 561


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 26/230 (11%)

Query: 32  SAERTAQKRKFPSPPHSSNGHSP---QDTSTSP----IKKKKKPGLLNSNNKEQDGRNDF 84
           S   T+++    S    S G  P   QD S++     +   +K  L     +++D  N+ 
Sbjct: 768 SQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNED 827

Query: 85  YCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC---IETQSK 139
           +C VC   G++LCCE CP+V+H  C    LT+ P G+W C  C  ++  E     +  S 
Sbjct: 828 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSH 887

Query: 140 AMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIFHPMDLC 191
                  E L  L     +K ++          + AFQ PVPL   PDY + I +PMDL 
Sbjct: 888 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIKNPMDLS 946

Query: 192 TLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 239
           T++K  ++   MY   E F+AD + I  NC  +N  +   +++A   IK+
Sbjct: 947 TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 993


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 26/230 (11%)

Query: 32  SAERTAQKRKFPSPPHSSNGHSP---QDTSTSP----IKKKKKPGLLNSNNKEQDGRNDF 84
           S   T+++    S    S G  P   QD S++     +   +K  L     +++D  N+ 
Sbjct: 734 SQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNED 793

Query: 85  YCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC---IETQSK 139
           +C VC   G++LCCE CP+V+H  C    LT+ P G+W C  C  ++  E     +  S 
Sbjct: 794 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSH 853

Query: 140 AMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIFHPMDLC 191
                  E L  L     +K ++          + AFQ PVPL   PDY + I +PMDL 
Sbjct: 854 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIKNPMDLS 912

Query: 192 TLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 239
           T++K  ++   MY   E F+AD + I  NC  +N  +   +++A   IK+
Sbjct: 913 TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959


>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
            sapiens]
          Length = 1110

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 60/189 (31%), Positives = 88/189 (46%), Gaps = 15/189 (7%)

Query: 72   NSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKIT 129
            + NNK+ D   D +C VC   G +LCCE CP+V+H  C    L S P GDW C  C  I 
Sbjct: 877  DGNNKDDDPNED-WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIG 935

Query: 130  VAEC------IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYA 181
              E       ++   K  T   +  +      +  +       +  FQ+PVP    P+Y 
Sbjct: 936  KPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYY 994

Query: 182  EYIFHPMDLCTLEKNAKKKM---YGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIK 238
            + I  PMDL T++K  +KK    Y   + F+AD + I  NC  +N  + ++ Q  K V  
Sbjct: 995  KIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVAL 1054

Query: 239  ICEHEMNEI 247
              E ++ EI
Sbjct: 1055 YFEDKLTEI 1063


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
            [Homo sapiens]
          Length = 1127

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 15/165 (9%)

Query: 72   NSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKIT 129
            + NNK+ D   D +C VC   G +LCCE CP+V+H  C    L S P GDW C  C  I 
Sbjct: 877  DGNNKDDDPNED-WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIG 935

Query: 130  VAEC------IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYA 181
              E       ++   K  T   +  +      +  +       +  FQ+PVP    P+Y 
Sbjct: 936  KPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYY 994

Query: 182  EYIFHPMDLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYN 223
            + I  PMDL T++K  +KK    Y   + F+AD + I  NC  +N
Sbjct: 995  KIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN 1039


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 127/702 (18%), Positives = 255/702 (36%), Gaps = 14/702 (1%)

Query: 422  SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
            SD   S  S +S   +    + D+   + SS  S S +S D  D S +S + + + ++ S
Sbjct: 572  SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 482  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLI 541
             S      S    +  +  +D + ++ S  + N   S    D  + S S    ++     
Sbjct: 632  DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 542  SPKRQIRSRFQLNLDKT-IESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600
            S      S    + D +  +S  +    N  S D  ++     S+ S  SDSSDS   S+
Sbjct: 692  SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751

Query: 601  DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660
                S +             D   S+       +N      +   +S +S+ ++     D
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 661  KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720
             +        +     +     D     D +DS     G DSDS +        D S   
Sbjct: 812  SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871

Query: 721  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780
               N  +  + S   +    +  S +  S     +     S +  S+  + ++ S++S+ 
Sbjct: 872  DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 781  TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840
               +   + +             +++        +S +    + + S S+ +     S+ 
Sbjct: 932  NSNSSDSSNSSDSSDSSDSSNSSDSSN-------SSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 841  SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900
            SS    SS S  +  SS ++D   ++ S+D  +  +  +S   D+   + +   +D S +
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 901  TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELT-MAEMRQSLEQERDRLIAEVKKQ 959
            +  S  ++        +        + S+   + + +  +E   S +       ++    
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 960  LELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ 1019
             +        ++      +N    +      ++S        +   E   S   S ++  
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162

Query: 1020 QE-ADAEVNTETLNKS-SQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1077
             + +D+  ++++ + S S  SS S+ S+ S  +S S +   S++ S  S S+     S  
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222

Query: 1078 TPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1119
            + SS    SN+ SD S S+ SS  SS+    S  SD + STS
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSS-DSSNSSDSSDSSDSSDSTS 1263



 Score = 77.0 bits (188), Expect = 9e-14
 Identities = 131/700 (18%), Positives = 258/700 (36%), Gaps = 42/700 (6%)

Query: 430  STNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPF 489
            S++S+  + SD        ++ S  S S  S D  D S +S +S  +  + S S S K  
Sbjct: 571  SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 490  SPQLSAPITTKTDKTSTTGSILNLNLDRSKAE-----MDLKELSESVQQQSTPVPLISPK 544
            S   S+   +K+D + +  S  + N D S +       D  + S+S    S+     S  
Sbjct: 631  SD--SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688

Query: 545  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604
                S    + + +  S  +    ++ S+   +    SDS+ S  SDSSDS   SD    
Sbjct: 689  SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS--NSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 605  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664
            S +             +   S+       ++      +   +S +S+ +D     D ++ 
Sbjct: 747  SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 665  EPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKN 724
                D S+ +        D     D +DS       DS   S+       D S R    N
Sbjct: 807  SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD---GSDSDSSNRSDSSN 863

Query: 725  KKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTA 784
              +  + S   +    +  S +  S +  ++   + SS   S+  + ++ S+ S+ +  +
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923

Query: 785  PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPL 844
               + +             +++ +      +S++      + S ++S  +   S+ SS  
Sbjct: 924  SESSNSSDNSNSSDSSNSSDSSDSSD----SSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979

Query: 845  VTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGS 904
              SS S  +  SS ++D   ++ S+D     +  +S   D+   + +   +D S ++  S
Sbjct: 980  SNSSDSSDSSDSSDSSDSSDSSNSSD-----SSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034

Query: 905  TIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEK 964
              ++                 + S+   + + + +          D   ++     +   
Sbjct: 1035 DSSD---------------SSDSSDSSDSSDSSDSSNSSDSSDSSDS--SDSSDSSDSSD 1077

Query: 965  QQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADA 1024
                 E+      +N    +      ++S        +   +   S   S ++   ++  
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137

Query: 1025 EVNTETLNKSSQGSSSS--TQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSI 1082
              N+   + SS+ S SS  + S+ S  +S S +   S++ S  S S+     S  + SS 
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 1083 LLGSNQGSDHSRSNKSSWSS--SDEKRGSTRSDHNTSTST 1120
               S+  SD S S+ SS SS  SD    S  SD N S+ +
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 129/706 (18%), Positives = 258/706 (36%), Gaps = 65/706 (9%)

Query: 422  SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
            SD   S  S+NSS  + S    D+   ++SS  S S +S D  D S +S +S  +  + S
Sbjct: 651  SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710

Query: 482  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAE--MDLKELSESVQQQSTPVP 539
             S      S   S+   +     S+  S  + + D S +    D  + S+S     +   
Sbjct: 711  DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770

Query: 540  LISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYIS 599
              S      S    + D +  S  +    +  S +   + + SDS DS+ S+SSDS   S
Sbjct: 771  SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830

Query: 600  D--DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGA 657
            D  D   S +  + ++  +G   D    +       ++          +S +S  +D   
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS---------DSSDSSNSSDSSD 881

Query: 658  VKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS 717
              D        D S+ +  S     D     D +DS       +S + S        D+S
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS--------DNS 933

Query: 718  GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTS 777
                  N  +  + S   +        ++  S+S   +     S + +S +  ++ +S S
Sbjct: 934  NSSDSSNSSDSSDSSDSSN--------SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985

Query: 778  STVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVT 837
            S  + ++ +  ++ S                      NSS       +   S S+     
Sbjct: 986  SDSSDSSDSSDSSDSS---------------------NSSDSSDSSDSSDSSNSS----D 1020

Query: 838  STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 897
            S+ SS    SS S  +  SS ++D   ++ S+D     +  +S   D+   + +   +D 
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----SSNSSDSSDSSDSSDSSDSSDS 1075

Query: 898  SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 957
            S ++  S  ++        +        + S+   + + + +    +     D   ++  
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS--SDSS 1133

Query: 958  KQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATA 1017
               +        ++ +    ++    +      ++S        ++  +   S   S ++
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193

Query: 1018 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETS----AEKSKESGSTLDLS 1073
               ++    ++   + SS  S SS  S  S+++ +S   E+S    +  S +S ++ D S
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253

Query: 1074 GSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1119
             S ++  S    +++    S+S   + + SD    S  SD N STS
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 99/546 (18%), Positives = 203/546 (37%), Gaps = 30/546 (5%)

Query: 582  SDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKE 641
            SDS DS+ SDSS+S   SD      ++   + D +    D   S+       +N  +  +
Sbjct: 547  SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606

Query: 642  ELKSTSPASEKADPGAVKDKASPEPE-KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGL 700
               S+  +       +  D +  E +  D   K+  S     D     D +DS       
Sbjct: 607  SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 701  DSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTR 760
            DS   S+       D S      N  +  + S   +    +  S +  S S   +     
Sbjct: 667  DSSDSSD-----SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 761  SSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQ 820
            +S+ + ++ ++ ++ +S++   +  + ++  S                      ++S+  
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--------------SNSSDS 767

Query: 821  QKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880
                  S S+ +     S  SS    SS S ++  SS ++D   ++ S+D  +  +  +S
Sbjct: 768  SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827

Query: 881  KMMDAIKGTMTEIYNDLSKNTTGSTIAEIRR-----LRIEIEKLQWLHQQELSEMKHNLE 935
               D+   + +   +D S ++ GS      R          +     +  + S+   + E
Sbjct: 828  NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887

Query: 936  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995
             + +          D   ++     +        ++ +    +N    +      N+S  
Sbjct: 888  SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES---SNSSDNSNSSDSSNSSDS 944

Query: 996  DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKS-SQGSSSSTQSAPSETASASK 1054
                  ++  +   S   S ++   ++++  ++++ N S S  SS S+ S+ S  +S S 
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004

Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1114
            +   S++ S  S S+   + S  + SS    S+  SD S S+ SS  SSD    S  SD 
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDS 1063

Query: 1115 NTSTST 1120
            + S+ +
Sbjct: 1064 SDSSDS 1069



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 104/563 (18%), Positives = 206/563 (36%), Gaps = 44/563 (7%)

Query: 563  KAQLGINEISEDVYTAVEHSDSE-DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMD 621
            K+  G +  S D     + ++SE D+  S   D+ Y SD+ + + N      D +G + D
Sbjct: 458  KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG----SDSKGAEDD 513

Query: 622  KEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681
               S        TN  +      + +  ++K+D G  K  +S     D S  +  S    
Sbjct: 514  DSDST-----SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD 568

Query: 682  KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGR--KNKKEPKEPSPKQDVVG 739
             D       +DS +     DSDS      D  +  +  +     +  +  + S   D   
Sbjct: 569  SDSSDSNSSSDSDSS----DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624

Query: 740  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799
             +  S +  S S  ++     +S+ +S    ++ +S SS  + ++ +  ++ S       
Sbjct: 625  DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 800  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859
                           NSS       + + S S+     S+ SS   +S  S S+  +S +
Sbjct: 685  ---------------NSSDSSDSSDSSNSSESS----DSSDSSDSDSSDSSDSSNSNSSD 725

Query: 860  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919
            +D   ++ S+D        +S   D+   + +   +D S ++  S  ++        +  
Sbjct: 726  SDSSNSSDSSD--------SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 920  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979
               +  + ++  ++ + + +          D   +      +         +      +N
Sbjct: 778  DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 980  CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039
                +      + S  D   +         S +  ++     +D+  + E+ N S    S
Sbjct: 838  SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897

Query: 1040 SSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSS 1099
            S++  + S  +S S +   S+  S  S S+     S  + SS    S+  SD S S+ SS
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 1100 WSSSDEKRGSTRSDHNTSTSTKS 1122
             +SSD    S  SD N+S S+ S
Sbjct: 958  -NSSDSSNSSDSSDSNSSDSSDS 979



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 15/115 (13%)

Query: 1023 DAEVNTETLNKSSQGSSSSTQSAPSETASASK-EKETSAEKSKESGSTLDLSGSRETPSS 1081
            D  +  +  N S + + +   ++ S+  S+S+ +   ++++SK++G+  D  G+ +  S 
Sbjct: 457  DKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD 516

Query: 1082 ILL----------GSNQGSDHSRSN----KSSWSSSDEKRGSTRSDHNTSTSTKS 1122
                         G+N   D+ +S+    KS  S SD    S  SD + S+ + S
Sbjct: 517  STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 17/202 (8%)

Query: 43   PSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVC---HREGQV-LCC 98
            P+ P +S     ++   S  K KKK  ++++ +KE       YC +C   + E +  + C
Sbjct: 2685 PTLPAASQKRKREEEKDSSSKSKKKK-MISTTSKETKKDTKLYC-ICKTPYDESKFYIGC 2742

Query: 99   ELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK- 154
            + C   YH +C+  L SE E   ++ CP+C+    A  + T    +T    E L  +L+ 
Sbjct: 2743 DRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLRS 2799

Query: 155  FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKW 214
                KM  P    F +PV     PDY   I  PMDL T+E+  +++ Y     F+AD   
Sbjct: 2800 LQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2855

Query: 215  ILHNCIIYNGGNHKLTQIAKVV 236
            I  NC  YN  +    Q A+V+
Sbjct: 2856 IFDNCRYYNPSDSPFYQCAEVL 2877



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 83  DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 137
           D +C VCH+ G +LCCE C  VYH +C++  L   PE +W C  C   K+  V +C+   
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449

Query: 138 SKAMTMLTIEQLSY 151
            K    +  E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 52/238 (21%), Positives = 95/238 (39%), Gaps = 15/238 (6%)

Query: 715 DHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATT 774
           ++  ++  KN++E ++ S ++D   KTP        S   T V  + ++ ++  G   T 
Sbjct: 584 ENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTN 643

Query: 775 STSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTIT 834
           +TS     T+P+   +      + P    +++   ++ V +       E       S+ T
Sbjct: 644 ATSEE---TSPSEGRSPVGCLSETP----DSSNMAEKKVASELPQDVPEEPNKTCESSNT 696

Query: 835 LVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIY 894
             T+T   P + +S S S L SS +     A    +   +     S   + +    +E  
Sbjct: 697 SATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKS 756

Query: 895 N-DLS------KNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSL 945
           N +LS      K  +GST   I RLR    KL  L  Q+++   H       E ++ L
Sbjct: 757 NGELSESPGAGKGASGST-RIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVL 813



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)

Query: 635  NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 690
            N  E K  L S+S A      G  +D     P   E D ++   PS   P  + +   ++
Sbjct: 1605 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1659

Query: 691  TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 744
             +  T  +       + S+ ES L  D   D +G    KN+    E   K  +   T  +
Sbjct: 1660 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1718

Query: 745  TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 802
            +TV + S     V    + +  +S      +T T++T TVT  +  +TG  V        
Sbjct: 1719 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1771

Query: 803  KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 862
                  +  V   S TV    +T S +T+  TLVTS      V+   S    V  +    
Sbjct: 1772 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1821

Query: 863  PIATASADVAADIAKYTSK 881
            P  T S        K+ +K
Sbjct: 1822 PKKTRSGTALPSYRKFVTK 1840


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 17/202 (8%)

Query: 43   PSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVC---HREGQV-LCC 98
            P+ P +S     ++   S  K KKK  ++++ +KE       YC +C   + E +  + C
Sbjct: 2702 PTLPAASQKRKREEEKDSSSKSKKKK-MISTTSKETKKDTKLYC-ICKTPYDESKFYIGC 2759

Query: 99   ELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK- 154
            + C   YH +C+  L SE E   ++ CP+C+    A  + T    +T    E L  +L+ 
Sbjct: 2760 DRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLRS 2816

Query: 155  FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKW 214
                KM  P    F +PV     PDY   I  PMDL T+E+  +++ Y     F+AD   
Sbjct: 2817 LQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872

Query: 215  ILHNCIIYNGGNHKLTQIAKVV 236
            I  NC  YN  +    Q A+V+
Sbjct: 2873 IFDNCRYYNPSDSPFYQCAEVL 2894



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 83  DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 137
           D +C VCH+ G +LCCE C  VYH +C++  L   PE +W C  C   K+  V +C+   
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449

Query: 138 SKAMTMLTIEQLSY 151
            K    +  E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 51/258 (19%), Positives = 104/258 (40%), Gaps = 16/258 (6%)

Query: 727  EPKEPS-PKQDVVGKTPPSTTVGSHSPPET-PVLTRSSAQTSAAGATATTSTSSTVTVTA 784
            +P+ P+ P+     +    TTV SH P E  P   +SS    AA +   ++      V  
Sbjct: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRV 2343

Query: 785  PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST----VQQKEITQSPSTSTITLVTSTQ 840
             +P+ T     + RP  P + +P  Q  V  +++    +Q     Q PS          Q
Sbjct: 2344 QSPSQT-----RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398

Query: 841  SSPLVTSSG---SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 897
            SS    SSG   +  T+ S     L I      V A       + +  +    +++   +
Sbjct: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIA--VPQLQQQVQVLSQIQSQVVAQI 2456

Query: 898  SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 957
                +G       +L I+I++   +   ++  +      ++ E  Q ++Q RD+   + +
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516

Query: 958  KQLELEKQQAVDETKKKQ 975
            +Q+E++++  +  + + +
Sbjct: 2517 QQIEIKREHTLQASNQSE 2534



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)

Query: 635  NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 690
            N  E K  L S+S A      G  +D     P   E D ++   PS   P  + +   ++
Sbjct: 1479 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1533

Query: 691  TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 744
             +  T  +       + S+ ES L  D   D +G    KN+    E   K  +   T  +
Sbjct: 1534 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1592

Query: 745  TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 802
            +TV + S     V    + +  +S      +T T++T TVT  +  +TG  V        
Sbjct: 1593 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1645

Query: 803  KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 862
                  +  V   S TV    +T S +T+  TLVTS      V+   S    V  +    
Sbjct: 1646 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1695

Query: 863  PIATASADVAADIAKYTSK 881
            P  T S        K+ +K
Sbjct: 1696 PKKTRSGTALPSYRKFVTK 1714


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 124/605 (20%), Positives = 229/605 (37%), Gaps = 66/605 (10%)

Query: 538  VPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEY 597
            +P +S   +++S  ++ + +  E  K  + + E +E+     E ++ E+ E  +    E 
Sbjct: 429  IPSVSTHIKVKSEEKIKVVEKSE--KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486

Query: 598  ISDDEQKSKNEPEDTED---KEGCQMDKE-----------PSAVK--KKPKPTNPVEIKE 641
               +E++++   E+T+    +E    +KE           P+  K  +K +  +P E+K 
Sbjct: 487  EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546

Query: 642  ELKSTSPASEKADPGAVKDKASPE---PEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL 698
              K+ SPA E+A       K+ PE   PEK+ ++       P K K   K+E  SP    
Sbjct: 547  PEKAKSPAKEEA-------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA--- 596

Query: 699  GLDSDSESELVIDLGEDHSGREGRKN--KKEPKEPSP-KQDVVGKTPPSTTVGSHSPPET 755
              ++ S  +    + E+       K+  K+E K P+  K     K+P      S    ++
Sbjct: 597  --EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654

Query: 756  PVLTRSSAQTSA-----AGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ 810
            P    + +   A     A A +     S V   A +P    SPVK++     K  +P  +
Sbjct: 655  PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714

Query: 811  RVVWNSSTVQQ-KEITQSPSTSTITLVTSTQSSPLVTSSGSMSTL-VSSVNADLPIATAS 868
                        KE  ++P  +   +    +S     S     TL V S  A  P   A 
Sbjct: 715  EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP---AK 771

Query: 869  ADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRL-RIEIEKLQWLHQQEL 927
             +  +   K+  K    +K  +       S     S + E  +    EI K + +     
Sbjct: 772  EEARSPADKFPEKAKSPVKEEVK------SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825

Query: 928  SEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFY 987
             E K   E+ + E  +  E+E+     + +++ + +K++A  +   K      K+ A+  
Sbjct: 826  EEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE- 883

Query: 988  CCWNTSYCDYPCQQAHWPEHMKSCTQSATAP-----QQEADAEVNTETLNKSSQGSSSST 1042
                        ++    +  K  T    AP     +++A  +  TE   K    + +  
Sbjct: 884  ---KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940

Query: 1043 QSAPSETASASKE-KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS 1101
             S P+E   A+ E K+T  EK+K+           +     L  S + S          S
Sbjct: 941  PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL--SKEPSKPKAEKAEKSS 998

Query: 1102 SSDEK 1106
            S+D+K
Sbjct: 999  STDQK 1003



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 70/399 (17%), Positives = 147/399 (36%), Gaps = 39/399 (9%)

Query: 376 PTNPSAGT-AKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSS 434
           P  PS  T  K+  +EK+K+  + +    +++ +          ++  +   +       
Sbjct: 427 PKIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485

Query: 435 VHTGSDVEQDAEKKATSSH-----FSASEESMDFLDKSTASPASTKT---------GQAG 480
              G + E +  ++ T S       S  +E+   + +   SPA  K+          +  
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545

Query: 481 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540
           S   +  P   +  +P   K+ +     S   +     KA+   KE ++S  +  +P   
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEKA 604

Query: 541 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600
            SP ++             E  K+   +   S +   +    +++  EK+ S + E    
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVK--SPEKAKSPTKEEAKSPEKAKSPEKE---- 658

Query: 601 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVE--IKEELKSTSPASEKADPGAV 658
            E KS  + +     E    +K  S VK + K     +  +KEE KS   A       A 
Sbjct: 659 -EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717

Query: 659 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 718
             + +  P K+ ++  + +  P+K++ K  ++  SP          E    +D+    + 
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP----------EKAKTLDVKSPEAK 767

Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPV 757
              ++  + P +  P++    K+P    V S    ++P+
Sbjct: 768 TPAKEEARSPADKFPEK---AKSPVKEEVKSPEKAKSPL 803



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 64/324 (19%), Positives = 123/324 (37%), Gaps = 17/324 (5%)

Query: 426 RSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGS 485
           +SP    S     S  +++A+  A +    + E++   + +   SPA  K+         
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAK---SPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629

Query: 486 PKPFSPQLSAPITTKTDKTSTTGSILNLNLDRS--KAEMDLKELSESVQQQSTPVPLISP 543
            +  SP+ +   T +  K+            +S  KA+  +K  ++S ++  +PV   + 
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689

Query: 544 KRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ 603
             +          K+ E  K+ +     S +   +    +++  EK+ S   E     E+
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749

Query: 604 KSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKAS 663
               E   T D +  +         + P    P + K  +K    + EKA     +D  +
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809

Query: 664 PE---PEKD-----FSEKAKPSPHPIKDKLKGKDETDSP-TVHLGLDSDSESELVIDLGE 714
           PE   P+K+       E+ KP    +K+  K  +E  +P T       DS+ E   +  +
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE---EAPK 866

Query: 715 DHSGREGRKNKKEPKEPSPKQDVV 738
             + +   + KKEP    PK+  V
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKV 890



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 70/322 (21%), Positives = 123/322 (38%), Gaps = 25/322 (7%)

Query: 426  RSPMSTNSSVH----TGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
            +SP    S V     T    +   +++A S   + S E    LD    SP +    +  +
Sbjct: 717  KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD--VKSPEAKTPAKEEA 774

Query: 482  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSES-VQQQSTP--V 538
             S + K F  +  +P+  +        S L  +    + E+  KE  +S V+++  P  V
Sbjct: 775  RSPADK-FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833

Query: 539  PLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYI 598
             +  P ++          KT E   ++       E     VE       EK   S  E  
Sbjct: 834  KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 599  SDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAV 658
             ++ +  K  P   ++       KE +  K+K       E+ ++    + A E + P A 
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK------TEVAKKEPDDAKAKEPSKP-AE 946

Query: 659  KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 718
            K +A+PE +    EKAK      K K + K + D  T+     S   S+   +  E  S 
Sbjct: 947  KKEAAPEKKDTKEEKAKKPEE--KPKTEAKAKEDDKTL-----SKEPSKPKAEKAEKSSS 999

Query: 719  REGRKNKKEPKEPSPKQDVVGK 740
             + +K+ K P++ +  +   GK
Sbjct: 1000 TD-QKDSKPPEKATEDKAAKGK 1020


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 68/259 (26%), Positives = 107/259 (41%), Gaps = 44/259 (16%)

Query: 46   PHSSNGHSPQD---TSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCP 102
            P    G SP++      +P  KK  P  +          N+ +C VC   G++LCC+ CP
Sbjct: 939  PPEVEGTSPEEHRLIPRTPGAKKGPPAPIE---------NEDFCAVCLNGGELLCCDRCP 989

Query: 103  RVYHAKC--LRLTSEPEGDWFCPECEKITVAE--------CIE----TQSKAMTMLTIEQ 148
            +V+H  C    L S P G+W C  C  +T  E        C        S  ++M   ++
Sbjct: 990  KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK 1049

Query: 149  LSYL-LKFAIQKMKQPGTDAFQKPV-PLEQHPDYAEYIFHPMDLCTLEKNAKKK---MYG 203
               L L      +  P    F +PV PL +H  Y + I  PMDL  + +  +KK    Y 
Sbjct: 1050 CEKLVLSLCCNNLSLP----FHEPVSPLARH--YYQIIKRPMDLSIIRRKLQKKDPAHYT 1103

Query: 204  CTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDN 263
              E  ++D + +  NC  +N  + ++ +  + +    E  + EI   PE   A  ++ D+
Sbjct: 1104 TPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEI--YPEKRFAQPRQEDS 1161

Query: 264  WFCE-----PCSNPHPLVW 277
               E      CS P    W
Sbjct: 1162 DSEEVSSESGCSTPQGFPW 1180



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 10/96 (10%)

Query: 464 LDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTT----GSILNLNLDRSK 519
           LDK+TA+     +G+   LS  P   + Q S+P   +   TS +     + L + L  ++
Sbjct: 588 LDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTR 647

Query: 520 AEMDLKELSESVQQ------QSTPVPLISPKRQIRS 549
            E  L+   +SV        Q+ P  L +P + + S
Sbjct: 648 LERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSS 683


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)

Query: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420
           R+P  PN +       T     + +I ++  V  N + ++S     S    S  T R+I 
Sbjct: 94  RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 142

Query: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 478
            S    +       +    + +   +KK T       E    +D  D    +P  T T Q
Sbjct: 143 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 201

Query: 479 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 533
              +S SPK     P +P+ S P  + T K ++        ++  +     K+ S   ++
Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261

Query: 534 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 593
           ++T         +  ++      K +     +         + T  E + +   E + ++
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321

Query: 594 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 648
             E      + +     EP  T  K      KEP+    K+P PT P E      K  +P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 649 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 708
            + K+ P   K+ A   P+K       P+P   K+      +  +PT        ++   
Sbjct: 382 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434

Query: 709 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 765
                E       +     PKEP+P      K P  TT    SP  P+ P   T  SA T
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491

Query: 766 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 811
           +      TT+ S+  T   P+P  T  P     P  PKE AP   +
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 533



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 211

Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 212 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 267

Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 268 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 327

Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 328 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 375

Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                                      KEP+P       T P     +      P   + 
Sbjct: 376 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409

Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469

Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 470 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840

Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 841 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 888

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 889 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 936

Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 937 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 977



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 550

Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 551 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 604 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660

Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 718

Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 719 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 752

Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 805

Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 862

Query: 883 MDAIKGTMTEIYND 896
             A K  MT    D
Sbjct: 863 PAATKPEMTTTAKD 876



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)

Query: 446 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 505
           ++ ++SS  S+S  ++  +  S  S A+ +  +   +  + K  + +   P     D+  
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 182

Query: 506 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 565
           +        LD    ++   + S +   + +  P I+  + I  R  L  +         
Sbjct: 183 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 226

Query: 566 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 624
              ++ S++    V    + +++++ +++ +  +D ++K+ +  E    ++    D  P 
Sbjct: 227 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283

Query: 625 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681
           S V  KP P      K E  +  PA    ++  P   K+ AS  P++       P+P  I
Sbjct: 284 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 330

Query: 682 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 741
           K          +PT                                PKEP+P       T
Sbjct: 331 KS---------APTT-------------------------------PKEPAPTTTKSAPT 350

Query: 742 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 801
            P     + +    P   +  A T+      TT+ S+  T   PAP       KK  P  
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 406

Query: 802 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 832
           PKE AP   +    ++  +    T+ P+ +T
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 302

Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 303 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 358

Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418

Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478

Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538

Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598

Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 719 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 767

Query: 842 SPLVTSS 848
            P  T+S
Sbjct: 768 GPTSTTS 774



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)

Query: 624 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 683
           P + KK P P+      + +KST+  S K  P   K K   E E + +E+   S +  ++
Sbjct: 72  PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 124

Query: 684 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 743
                  + S +    + S   S    +L +    ++ +KN+ + K+P+PK  VV +   
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 183

Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803
               G                      T  TST+    V+      T  P+   RP LP 
Sbjct: 184 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 225

Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 863
            +  + +     S TV ++   ++  T+T    TST      TS+    ++  +   DL 
Sbjct: 226 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 280

Query: 864 IATASADVAADIAKYTSKMMDAIKG 888
                A  +  +AK T K     KG
Sbjct: 281 -----APTSKVLAKPTPKAETTTKG 300



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 425  PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484
            P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 806  PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 856

Query: 485  SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544
             P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 857  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916

Query: 545  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604
             Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 917  TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 957

Query: 605  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664
              N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 958  --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1009

Query: 665  EPEKDFSEKAKPSP 678
             P K  S   + +P
Sbjct: 1010 TPRKMTSTMPELNP 1023


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)

Query: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420
           R+P  PN +       T     + +I ++  V  N + ++S     S    S  T R+I 
Sbjct: 135 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 183

Query: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 478
            S    +       +    + +   +KK T       E    +D  D    +P  T T Q
Sbjct: 184 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 242

Query: 479 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 533
              +S SPK     P +P+ S P  + T K ++        ++  +     K+ S   ++
Sbjct: 243 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302

Query: 534 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 593
           ++T         +  ++      K +     +         + T  E + +   E + ++
Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362

Query: 594 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 648
             E      + +     EP  T  K      KEP+    K+P PT P E      K  +P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 649 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 708
            + K+ P   K+ A   P+K       P+P   K+      +  +PT        ++   
Sbjct: 423 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475

Query: 709 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 765
                E       +     PKEP+P      K P  TT    SP  P+ P   T  SA T
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532

Query: 766 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 811
           +      TT+ S+  T   P+P  T  P     P  PKE AP   +
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 574



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 252

Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 253 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 308

Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 309 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 368

Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 369 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 416

Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                                      KEP+P       T P     +      P   + 
Sbjct: 417 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450

Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510

Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 511 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 608  EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665
            EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 764  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 666  PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721
              K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 822  TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881

Query: 722  RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
             +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 882  AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 929

Query: 782  VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837
             T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 930  TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 977

Query: 838  STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880
            +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 978  TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 1018



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 591

Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 592 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 645 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701

Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 759

Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 760 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 793

Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 846

Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 903

Query: 883 MDAIKGTMTEIYND 896
             A K  MT    D
Sbjct: 904 PAATKPEMTTTAKD 917



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)

Query: 446 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 505
           ++ ++SS  S+S  ++  +  S  S A+ +  +   +  + K  + +   P     D+  
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 223

Query: 506 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 565
           +        LD    ++   + S +   + +  P I+  + I  R  L  +         
Sbjct: 224 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 267

Query: 566 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 624
              ++ S++    V    + +++++ +++ +  +D ++K+ +  E    ++    D  P 
Sbjct: 268 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324

Query: 625 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681
           S V  KP P      K E  +  PA    ++  P   K+ AS  P++       P+P  I
Sbjct: 325 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 371

Query: 682 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 741
           K          +PT                                PKEP+P       T
Sbjct: 372 KS---------APTT-------------------------------PKEPAPTTTKSAPT 391

Query: 742 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 801
            P     + +    P   +  A T+      TT+ S+  T   PAP       KK  P  
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 447

Query: 802 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 832
           PKE AP   +    ++  +    T+ P+ +T
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 343

Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 344 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 399

Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459

Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519

Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579

Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639

Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 760 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 808

Query: 842 SPLVTSS 848
            P  T+S
Sbjct: 809 GPTSTTS 815



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)

Query: 624 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 683
           P + KK P P+      + +KST+  S K  P   K K   E E + +E+   S +  ++
Sbjct: 113 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 165

Query: 684 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 743
                  + S +    + S   S    +L +    ++ +KN+ + K+P+PK  VV +   
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 224

Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803
               G                      T  TST+    V+      T  P+   RP LP 
Sbjct: 225 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 266

Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 863
            +  + +     S TV ++   ++  T+T    TST      TS+    ++  +   DL 
Sbjct: 267 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 321

Query: 864 IATASADVAADIAKYTSKMMDAIKG 888
                A  +  +AK T K     KG
Sbjct: 322 -----APTSKVLAKPTPKAETTTKG 341



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 425  PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484
            P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 847  PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 897

Query: 485  SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544
             P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 898  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957

Query: 545  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604
             Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 958  TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 998

Query: 605  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664
              N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 999  --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1050

Query: 665  EPEKDFSEKAKPSP 678
             P K  S   + +P
Sbjct: 1051 TPRKMTSTMPELNP 1064


>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)

Query: 149  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K++Y   E 
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444

Query: 208  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 160  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219
            M  P +  F  PV  +  PDY + I +PMDL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579

Query: 220  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            + YNG   + T+ A+ ++ +C   + E +
Sbjct: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608


>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
          Length = 1893

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)

Query: 149  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K++Y   E 
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465

Query: 208  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1506



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 160  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219
            M  P +  F  PV  +  PDY + I +PMDL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1541 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1600

Query: 220  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            + YNG   + T+ A+ ++ +C   + E +
Sbjct: 1601 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1629


>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
            sapiens]
          Length = 1826

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)

Query: 149  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K +Y   E 
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463

Query: 208  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 160  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219
            M  P +  F  PV  +  PDY + I +P+DL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598

Query: 220  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248
            + YNG   + T+ A+ ++ IC   + E +
Sbjct: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)

Query: 440 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 492
           D +++  KK  +      +E+   LD      +   T T Q   +S SPK     P +P+
Sbjct: 68  DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127

Query: 493 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 552
            S P  + T K ++        ++  +     K+ S   ++++T         +  ++  
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187

Query: 553 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 609
               K +     +         + T  E + +   E + ++  E      + +     EP
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247

Query: 610 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 667
             T  K      KEP+    K+P PT P E      K  +P + K+ P   K+ A   P+
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307

Query: 668 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 727
           K       P+P   K+      +  +PT        ++        E       +     
Sbjct: 308 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360

Query: 728 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 784
           PKEP+P      K P  TT    SP  P+ P   T  SA T+      TT+ S+  T   
Sbjct: 361 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417

Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQR 811
           P+P  T  P     P  PKE AP   +
Sbjct: 418 PSPTTTKEPA----PTTPKEPAPTTPK 440



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 77  KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 118

Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 119 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 174

Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234

Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 235 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 282

Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                                      KEP+P       T P     +      P   + 
Sbjct: 283 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316

Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376

Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 377 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747

Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 748 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 795

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 796 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 843

Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 844 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 884



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 457

Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 458 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510

Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 511 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567

Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 625

Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 626 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 712

Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 769

Query: 883 MDAIKGTMTEIYND 896
             A K  MT    D
Sbjct: 770 PAATKPEMTTTAKD 783



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 209

Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 265

Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325

Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385

Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445

Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505

Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 626 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 674

Query: 842 SPLVTSS 848
            P  T+S
Sbjct: 675 GPTSTTS 681



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484
           P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 713 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 763

Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544
            P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823

Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604
            Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 824 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 864

Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664
             N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 865 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 916

Query: 665 EPEKDFSEKAKPSP 678
            P K  S   + +P
Sbjct: 917 TPRKMTSTMPELNP 930



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 778
           ++ +KN+ + K+P+PK  VV +       G                      T  TST+ 
Sbjct: 67  KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 108

Query: 779 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 838
              V+      T  P+   RP LP  +  + +     S TV ++   ++  T+T    TS
Sbjct: 109 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 163

Query: 839 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 888
           T      TS+    ++  +   DL      A  +  +AK T K     KG
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 207


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)

Query: 440 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 492
           D +++  KK  +      +E+   LD      +   T T Q   +S SPK     P +P+
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168

Query: 493 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 552
            S P  + T K ++        ++  +     K+ S   ++++T         +  ++  
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228

Query: 553 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 609
               K +     +         + T  E + +   E + ++  E      + +     EP
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288

Query: 610 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 667
             T  K      KEP+    K+P PT P E      K  +P + K+ P   K+ A   P+
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348

Query: 668 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 727
           K       P+P   K+      +  +PT        ++        E       +     
Sbjct: 349 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401

Query: 728 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 784
           PKEP+P      K P  TT    SP  P+ P   T  SA T+      TT+ S+  T   
Sbjct: 402 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458

Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQR 811
           P+P  T  P     P  PKE AP   +
Sbjct: 459 PSPTTTKEPA----PTTPKEPAPTTPK 481



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 118 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 159

Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 160 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 215

Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275

Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 276 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 323

Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                                      KEP+P       T P     +      P   + 
Sbjct: 324 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357

Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417

Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 418 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788

Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 789 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 836

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 837 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 884

Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 885 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 925



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 498

Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 499 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551

Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 552 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608

Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 666

Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 667 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 753

Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 810

Query: 883 MDAIKGTMTEIYND 896
             A K  MT    D
Sbjct: 811 PAATKPEMTTTAKD 824



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 250

Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 306

Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366

Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426

Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486

Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546

Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 667 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 715

Query: 842 SPLVTSS 848
            P  T+S
Sbjct: 716 GPTSTTS 722



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484
           P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 754 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 804

Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544
            P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864

Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604
            Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 865 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 905

Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664
             N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 906 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 957

Query: 665 EPEKDFSEKAKPSP 678
            P K  S   + +P
Sbjct: 958 TPRKMTSTMPELNP 971



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 778
           ++ +KN+ + K+P+PK  VV +       G                      T  TST+ 
Sbjct: 108 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 149

Query: 779 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 838
              V+      T  P+   RP LP  +  + +     S TV ++   ++  T+T    TS
Sbjct: 150 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 204

Query: 839 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 888
           T      TS+    ++  +   DL      A  +  +AK T K     KG
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 248


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 16/94 (17%)

Query: 48  SSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDF------------YCWVCHREGQV 95
           S N +S  D STS   + +K   L +  K++ G  +             YC VC + G++
Sbjct: 325 SINSYSVSDGSTSRSSRSRKK--LRTTKKKKKGEEEVTAVDGYETDHQDYCEVCQQGGEI 382

Query: 96  LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127
           + C+ CPR YH  CL   +   PEG W CP CEK
Sbjct: 383 ILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK 416



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 2/52 (3%)

Query: 76  KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125
           +E+D  +  +C VC   G++LCC+ CP  YH  CL   L   P G+W CP C
Sbjct: 442 EEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRC 493



 Score = 37.7 bits (86), Expect = 0.062
 Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 36/242 (14%)

Query: 581 HSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN---PV 637
           H ++E+  + D S++E     ++K   +P D +  +  +  KE   + ++   ++   P 
Sbjct: 32  HPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPE 91

Query: 638 EIKEE----LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDS 693
            ++EE    L+S S  S+       K K  P+ EK    K K      +++ +  D+ DS
Sbjct: 92  FVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRK------EEEEEEDDDDDS 145

Query: 694 PTVHLGLDSDSESELVIDLG----------EDHSGREGRKNKKEPKEP--SPKQDVVGKT 741
                  +  S ++L+ D G          ED+      K   +   P  + K   +  +
Sbjct: 146 K------EPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVS 199

Query: 742 PPSTTVGS---HSPPETPVLTRSSAQTSAAGATATTSTSSTVTVT--APAPAATGSPVKK 796
                +G+         P    S A  +AA A A     S VT T  AP P     P++K
Sbjct: 200 KMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRK 259

Query: 797 QR 798
            +
Sbjct: 260 AK 261


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 7/107 (6%)

Query: 26  RSKDPGSAERTAQKRKFPSPP-HSSNGHSPQDTSTSPIKKK--KKPGLLNSNNKEQDGRN 82
           R K   S E   ++  F S   HS++  S    +     K+  KK  + + +  E D ++
Sbjct: 285 RKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQD 344

Query: 83  DFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127
             YC VC + G+++ C+ CPR YH  CL   L   PEG W CP CEK
Sbjct: 345 --YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEK 389



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 3/52 (5%)

Query: 76  KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125
           +E+D   +F C VC   G++LCC+ CP  YH  CL   L   P G+W CP C
Sbjct: 410 EEEDDHMEF-CRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 9/124 (7%)

Query: 613  EDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASE---KADPGAVKDKASPEPEKD 669
            E   G Q  ++P  V+  P   + VE ++  K  SPAS+   + +     +KA P PE+ 
Sbjct: 1578 EKDPGAQKPRQPLEVQALPAALDRVESED--KHESPASKERAREERPEETEKAPPSPEQL 1635

Query: 670  FSEKAKPSPHPIKDKLKGK---DETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKK 726
              E+  P    I DKL+        DS  +    D+ +E +  I+  ++    E  + KK
Sbjct: 1636 PREEVLPEKEKILDKLELSLIHSRGDSSELRPD-DTKAEEKEPIETQQNGDKEEDDEGKK 1694

Query: 727  EPKE 730
            E K+
Sbjct: 1695 EDKK 1698


>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
           [Homo sapiens]
          Length = 2000

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%)

Query: 47  HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95
           HS++G       T  +K+    +KK  +L     +  +E DG    +  YC VC + G++
Sbjct: 332 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 391

Query: 96  LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127
           + C+ CPR YH  CL   L   PEG W CP CEK
Sbjct: 392 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 76  KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125
           KE++  +  YC VC   G++LCC+ C   YH  CL   L   P G+W CP C
Sbjct: 449 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
           [Homo sapiens]
          Length = 1966

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%)

Query: 47  HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95
           HS++G       T  +K+    +KK  +L     +  +E DG    +  YC VC + G++
Sbjct: 332 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 391

Query: 96  LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127
           + C+ CPR YH  CL   L   PEG W CP CEK
Sbjct: 392 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 76  KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125
           KE++  +  YC VC   G++LCC+ C   YH  CL   L   P G+W CP C
Sbjct: 449 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500


>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
           [Homo sapiens]
          Length = 2059

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%)

Query: 47  HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95
           HS++G       T  +K+    +KK  +L     +  +E DG    +  YC VC + G++
Sbjct: 391 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 450

Query: 96  LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127
           + C+ CPR YH  CL   L   PEG W CP CEK
Sbjct: 451 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 484



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 76  KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125
           KE++  +  YC VC   G++LCC+ C   YH  CL   L   P G+W CP C
Sbjct: 508 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 571 ISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ------KSKNEPEDTEDKEGCQM--DK 622
           +SE+     E  D E+ E+ +++D +   DD++         +   D     GC +    
Sbjct: 17  VSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPP 76

Query: 623 EPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIK 682
            P      P P  P   K++++    A      G  K K  P+ +K+     KP   P K
Sbjct: 77  PPPPPPLPPPPPPPPPDKDDIRLLPSAL-----GVKKRKRGPKKQKE----NKPG-KPRK 126

Query: 683 DKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQ 735
            K +  +E        G + D   E     G ++    GRK +++ +E   K+
Sbjct: 127 RKKRDSEE------EFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKK 173


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 82/406 (20%), Positives = 147/406 (36%), Gaps = 26/406 (6%)

Query: 717  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 776
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 777  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 837  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 895
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T I +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS 716

Query: 896  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 955
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 956  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1015
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1016 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1075
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1076 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1121
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 415  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 469
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 470  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 527
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 528  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 587
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTA 725

Query: 588  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 647
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 648  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 707
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 708  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 762  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 820
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 821  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 879
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 880  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 938
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 939  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 998
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 999  CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1054
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1111
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1112 SDHNTSTSTKSLLPKESRL 1130
                T  ST SL P  + L
Sbjct: 1240 GSETTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 740  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 800  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 860  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 920  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 980  CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1040 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1086
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1087 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 116/563 (20%), Positives = 190/563 (33%), Gaps = 76/563 (13%)

Query: 375  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 432
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 433  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS--------- 481
             S  T +  E  +     AT S  + S E       S     +TK    GS         
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719

Query: 482  -------LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE-------- 526
                   ++GS    +    +  TT + + S T S      + + A     E        
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 527  ----LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHS 582
                ++ ++  ++T V   S K  + + F  N + TI S  A       SE   T V  +
Sbjct: 780  SETTMASTIGSETTKVSTASSK--MTTVFTENSETTIASTTA-------SET--TTVSTA 828

Query: 583  DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEE 642
             SE    S +      +   + S+     TE  E      E S      + T    I  E
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIGSE 882

Query: 643  LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702
              + S    +    + +   +     + SE    S    +      + +++ T      S
Sbjct: 883  TTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA-----S 937

Query: 703  DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762
               SEL        +G E      E  E +    +  +T  ++T GS    ET  ++ + 
Sbjct: 938  TEGSELTT---VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS----ETTTVSTAG 990

Query: 763  AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822
            ++T+    TA+   S T TV++     TGS          + T  + +     + T    
Sbjct: 991  SETT----TASIEGSETTTVSS-----TGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041

Query: 823  EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882
            E T   +T + T  TST+ S   T S + S   ++  ADL   T S   +      T+  
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-- 1099

Query: 883  MDAIKGTMTEIYNDLSKNTTGST 905
                    T +Y   SK TT ST
Sbjct: 1100 ----GSETTTVYITGSKTTTAST 1118



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 133/752 (17%), Positives = 262/752 (34%), Gaps = 87/752 (11%)

Query: 409  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 468
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 469  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 528
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 529  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 588
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 589  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 645
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 646  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 703
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 704  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 751
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 752  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 807
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 808  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 859
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 860  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 920  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979
                 +         E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTITSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 980  CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1040 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1096
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1097 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 735  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 794
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 795  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 851
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 852  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 907
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 908  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 967
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 968  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1025
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1026 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1080
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1120
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 407  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 466
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 467  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 525
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 526  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 585
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 586  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 641
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 642  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 702  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 759
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 760  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 819
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 820  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 868
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)

Query: 738  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 790
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 791  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 847
            GS          + + P+      N++ +   E T + + S   T T +T ++++ +  +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 848  SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 893
            +   +   ++V++   + T + DV+  I   T+  M   + T T +
Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 704  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 750
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 751  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 796
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 797  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 856
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330

Query: 857  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 905
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 43/185 (23%), Positives = 68/185 (36%), Gaps = 7/185 (3%)

Query: 721  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQT--SAAGATATTSTS- 777
            G K      E S    V   +  +TT  +     T V T  S  T  S  G+ ATTS++ 
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 778  -STVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836
             S  T T+   + T +            TA +       S +      T    TST +  
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229

Query: 837  TSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYND 896
             S  ++  +   GS +T+ S+ + + P AT+           T+    A   T++     
Sbjct: 1230 GSETNTAFII--GSETTIASTASLE-PTATSLTGSETTTVSITASGATAASTTVSSTTFV 1286

Query: 897  LSKNT 901
            L+K T
Sbjct: 1287 LTKAT 1291


>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
          Length = 680

 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 7/90 (7%)

Query: 43  PSPPHSSNGHSPQDTSTSPIKKKKKP----GLLNSNNKEQDGRNDFYCWVCHREGQVLCC 98
           P+ P SS+  SP++  T        P     L +  + + D   DF C VC + GQ+L C
Sbjct: 445 PTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSPTSTDGDIHEDF-CSVCRKSGQLLMC 503

Query: 99  ELCPRVYHAKCL--RLTSEPEGDWFCPECE 126
           + C RVYH  CL   L + P+G W CP C+
Sbjct: 504 DTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 533


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 717  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 776
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 777  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 837  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 895
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 896  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 955
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 956  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1015
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1016 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1075
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1076 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1121
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 136/736 (18%), Positives = 264/736 (35%), Gaps = 49/736 (6%)

Query: 415  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 469
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 470  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 527
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 528  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 587
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 588  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 647
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 648  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 707
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 708  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 762  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 820
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 821  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 879
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 880  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 938
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 939  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 998
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 999  CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1054
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1114
              ET+   +  S +T   +   ET ++   GS   +  +  ++++ + +     ST S  
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239

Query: 1115 NTSTSTKSLLPKESRL 1130
             + T+T  ++  E+ +
Sbjct: 1240 GSETNTAFIIGSETTI 1255



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 740  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 800  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 860  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 920  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 980  CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1040 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1086
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1087 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 375  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 432
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 433  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 490
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 491  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 542
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 543  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 602
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 603  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 662
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 663  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 720
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 721  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 777
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 778  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 830
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 831  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 890
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 891  TEIYNDLSKNTTGST 905
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 409  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 468
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 469  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 528
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 529  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 588
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 589  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 645
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 646  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 703
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 704  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 751
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 752  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 807
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 808  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 859
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 860  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 920  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 980  CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1040 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1096
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1097 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 135/719 (18%), Positives = 240/719 (33%), Gaps = 51/719 (7%)

Query: 412  SGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASP 471
            +G     +S +D   +  ST  S  T +         A+++    +  S +  + +T S 
Sbjct: 589  AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 472  ASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESV 531
              ++T    S +GS +  +    +  TT     S TGS   ++ + S         SE+ 
Sbjct: 649  TDSETTMV-STTGSERTITSTEGSETTT----VSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 532  QQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSD 591
            +  +T     S      +        +I   +      E SE    + E S++  +  + 
Sbjct: 704  KVSTTG----SETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 592  SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPV--EIKEELKSTSPA 649
            S  +   +   + +      +E      +  E + V         V  E  E   +++ A
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 650  SEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELV 709
            SE         +  P      SE    +     +      E    T      S++ +   
Sbjct: 820  SETTTVSTAGSETIPASTAG-SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 710  IDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAG 769
            I      +  EG +      E S       +    TTV +     T   T  S  T+A+ 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 770  -----ATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEI 824
                  T +T+ S T+TV+A     T              TA          ST   +  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT----TASTAGSETTTVSTAGSETT 994

Query: 825  TQSPSTSTITLVTSTQS-SPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMM 883
            T S   S  T V+ST S +  V+++G+ +T+ S+  ++    T +       A YT+   
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSE 1052

Query: 884  DAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQ 943
                 T TE     + +TTGS         +E   +        +      E T   +  
Sbjct: 1053 TTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITG 1110

Query: 944  SLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAH 1003
            S                E  +   V  T  +   A+     +       S          
Sbjct: 1111 S---------KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS---------- 1151

Query: 1004 WPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKS 1063
              E     T  + A    A     T T  + S+ +++ST  + + TAS +  + T+A  +
Sbjct: 1152 --ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209

Query: 1064 KESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS---SSDEKRGSTRSDHNTSTS 1119
                +T   SGS ET ++   GS   +  S  ++++ +    S+    ST S   T+TS
Sbjct: 1210 GSETTTASTSGS-ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1267



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 735  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 794
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 795  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 851
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 852  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 907
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 908  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 967
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 968  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1025
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1026 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1080
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1120
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 91/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 407  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 466
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 467  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 525
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 526  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 585
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 586  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 641
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 642  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 702  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 759
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 760  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 819
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 820  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 868
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ +
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 5/153 (3%)

Query: 744  STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803
            +TT  +     T   T  S  T+A+ A + T+T+ST        + +GS          +
Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE 1232

Query: 804  ETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTSSGSMSTLVSSVNA 860
             + P+      N++ +   E T + + S   T T +T ++++ +  ++   +   ++V++
Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292

Query: 861  DLPIATASADVAADIAKYTSKMMDAIKGTMTEI 893
               + T + DV+  I   T+  M   + T T +
Sbjct: 1293 TTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1323



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 23/166 (13%)

Query: 744  STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803
            +TTV + S   T   T  S  T+     + T+T ST+   A   +A GS           
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA--------- 1173

Query: 804  ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNAD 861
                        +++ +  E T + +  + T   ST  S   T+S  GS +T  S+  ++
Sbjct: 1174 -----------TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222

Query: 862  LPIATASADVAADIAKYTSKMMDA-IKGTMTEIYNDLSKNTTGSTI 906
               A  +    +  +   S+   A I G+ T I +  S   T +++
Sbjct: 1223 TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.123    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,938,830
Number of Sequences: 37866
Number of extensions: 2348693
Number of successful extensions: 25052
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 396
Number of HSP's successfully gapped in prelim test: 1190
Number of HSP's that attempted gapping in prelim test: 13648
Number of HSP's gapped (non-prelim): 8526
length of query: 1135
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1022
effective length of database: 13,968,660
effective search space: 14275970520
effective search space used: 14275970520
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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