BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo sapiens] (1135 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 2288 0.0 gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 2274 0.0 gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 2255 0.0 gi|238814389 zinc finger, MYND domain containing 11 isoform a [H... 186 1e-46 gi|238814385 zinc finger, MYND domain containing 11 isoform a [H... 186 1e-46 gi|238814387 zinc finger, MYND domain containing 11 isoform b [H... 182 2e-45 gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 91 6e-18 gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 91 6e-18 gi|74027251 tripartite motif-containing 33 protein isoform beta ... 90 1e-17 gi|74027249 tripartite motif-containing 33 protein isoform alpha... 81 6e-15 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 81 6e-15 gi|38788260 bromodomain PHD finger transcription factor isoform ... 75 5e-13 gi|38788274 bromodomain PHD finger transcription factor isoform ... 75 5e-13 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 5e-12 gi|209977097 tripartite motif-containing 66 [Homo sapiens] 70 9e-12 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 69 3e-11 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 69 3e-11 gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 68 4e-11 gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 68 4e-11 gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 67 1e-10 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 3e-10 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 3e-10 gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 64 8e-10 gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 64 8e-10 gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 63 1e-09 gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 63 1e-09 gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 63 1e-09 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 62 3e-09 gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 61 7e-09 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 60 1e-08 >gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo sapiens] Length = 1135 Score = 2288 bits (5928), Expect = 0.0 Identities = 1135/1135 (100%), Positives = 1135/1135 (100%) Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 Query: 61 PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW 120 PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW Sbjct: 61 PIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDW 120 Query: 121 FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY 180 FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY Sbjct: 121 FCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDY 180 Query: 181 AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC 240 AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC Sbjct: 181 AEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKIC 240 Query: 241 EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA 300 EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA Sbjct: 241 EHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDA 300 Query: 301 RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF 360 RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF Sbjct: 301 RFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPF 360 Query: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS Sbjct: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420 Query: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG 480 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG Sbjct: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAG 480 Query: 481 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL Sbjct: 481 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540 Query: 541 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD Sbjct: 541 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600 Query: 601 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD Sbjct: 601 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660 Query: 661 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE Sbjct: 661 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720 Query: 721 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV Sbjct: 721 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780 Query: 781 TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840 TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ Sbjct: 781 TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840 Query: 841 SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900 SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN Sbjct: 841 SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900 Query: 901 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL 960 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL Sbjct: 901 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL 960 Query: 961 ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ 1020 ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ Sbjct: 961 ELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQ 1020 Query: 1021 EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS 1080 EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS Sbjct: 1021 EADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPS 1080 Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD Sbjct: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135 >gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo sapiens] Length = 1160 Score = 2274 bits (5892), Expect = 0.0 Identities = 1135/1160 (97%), Positives = 1135/1160 (97%), Gaps = 25/1160 (2%) Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 Query: 61 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95 PIKKKKKPGLLNSNNKEQ DGRNDFYCWVCHREGQV Sbjct: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120 Query: 96 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF Sbjct: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180 Query: 156 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI Sbjct: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240 Query: 216 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL Sbjct: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300 Query: 276 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN Sbjct: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360 Query: 336 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN Sbjct: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420 Query: 396 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS Sbjct: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480 Query: 456 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL Sbjct: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540 Query: 516 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV Sbjct: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600 Query: 576 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN Sbjct: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660 Query: 636 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT Sbjct: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720 Query: 696 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET Sbjct: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780 Query: 756 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN Sbjct: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840 Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900 Query: 876 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960 Query: 936 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC Sbjct: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020 Query: 996 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080 Query: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1115 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1140 Query: 1116 TSTSTKSLLPKESRLDTFWD 1135 TSTSTKSLLPKESRLDTFWD Sbjct: 1141 TSTSTKSLLPKESRLDTFWD 1160 >gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo sapiens] Length = 1188 Score = 2255 bits (5844), Expect = 0.0 Identities = 1134/1188 (95%), Positives = 1134/1188 (95%), Gaps = 53/1188 (4%) Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60 Query: 61 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95 PIKKKKKPGLLNSNNKEQ DGRNDFYCWVCHREGQV Sbjct: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120 Query: 96 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF Sbjct: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180 Query: 156 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI Sbjct: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240 Query: 216 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL Sbjct: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300 Query: 276 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN Sbjct: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360 Query: 336 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN Sbjct: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420 Query: 396 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS Sbjct: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480 Query: 456 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL Sbjct: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540 Query: 516 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV Sbjct: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600 Query: 576 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN Sbjct: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660 Query: 636 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT Sbjct: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720 Query: 696 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET Sbjct: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780 Query: 756 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN Sbjct: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840 Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900 Query: 876 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960 Query: 936 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC Sbjct: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020 Query: 996 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080 Query: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS------------------------- 1090 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140 Query: 1091 ---DHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135 HSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD Sbjct: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188 >gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo sapiens] Length = 602 Score = 186 bits (471), Expect = 1e-46 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 22/275 (8%) Query: 82 NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135 +D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP C I + Sbjct: 99 HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155 Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195 +++ L+F + +MK+ D +K +HP Y + +D+ T+++ Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203 Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255 + Y E F ADA+ +LHN +I+ G + + IA+++ K HE++E+++C C+ Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFY 263 Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314 + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG H RAW+P Sbjct: 264 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 323 Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349 N ++ I K + A E+E++ +R Sbjct: 324 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358 Score = 95.9 bits (237), Expect = 2e-19 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460 Query: 876 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513 Query: 928 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 986 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++ Sbjct: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572 Query: 987 YCCWNTSYCDYPCQQAHW-PEHMKSC 1011 +CCWNTSYC CQQ HW EH ++C Sbjct: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598 >gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo sapiens] Length = 602 Score = 186 bits (471), Expect = 1e-46 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 22/275 (8%) Query: 82 NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135 +D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP C I + Sbjct: 99 HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155 Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195 +++ L+F + +MK+ D +K +HP Y + +D+ T+++ Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203 Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255 + Y E F ADA+ +LHN +I+ G + + IA+++ K HE++E+++C C+ Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFY 263 Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314 + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG H RAW+P Sbjct: 264 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 323 Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349 N ++ I K + A E+E++ +R Sbjct: 324 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358 Score = 95.9 bits (237), Expect = 2e-19 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%) Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460 Query: 876 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513 Query: 928 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 986 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++ Sbjct: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572 Query: 987 YCCWNTSYCDYPCQQAHW-PEHMKSC 1011 +CCWNTSYC CQQ HW EH ++C Sbjct: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598 >gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo sapiens] Length = 567 Score = 182 bits (461), Expect = 2e-45 Identities = 97/275 (35%), Positives = 150/275 (54%), Gaps = 23/275 (8%) Query: 82 NDFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPECEKITVAECIE 135 +D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP C I + Sbjct: 99 HDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPVCRSIKKKNTNK 155 Query: 136 TQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEK 195 +++ L+F + +MK+ D +K +HP Y + +D+ T+++ Sbjct: 156 -----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLVHSAVDVPTIQE 203 Query: 196 NAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL 255 + Y E F ADA+ +LHN +I+ G + + IA+++ K HE++E+++C C+ Sbjct: 204 KVNEGKYRSYEEFKADAQLLLHNTVIFYGDSEQ-ADIARMLYKDTCHELDELQLCKNCFY 262 Query: 256 AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG-QHDRAWVPIN 314 + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG H RAW+P Sbjct: 263 LSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSE 322 Query: 315 NCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 349 N ++ I K + A E+E++ +R Sbjct: 323 NIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 357 Score = 40.0 bits (92), Expect = 0.013 Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 17/170 (10%) Query: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875 + +V+ K+ P T ++ + P S+ST ++A P + + Sbjct: 400 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 459 Query: 876 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 927 S D T+I+ND K T + E + +LR E+E+ + +Q + Sbjct: 460 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 512 Query: 928 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQW 976 ++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQW Sbjct: 513 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQW 561 >gi|47419911 transcriptional intermediary factor 1 alpha isoform a [Homo sapiens] Length = 1050 Score = 90.9 bits (224), Expect = 6e-18 Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 26/230 (11%) Query: 32 SAERTAQKRKFPSPPHSSNGHSP---QDTSTSP----IKKKKKPGLLNSNNKEQDGRNDF 84 S T+++ S S G P QD S++ + +K L +++D N+ Sbjct: 768 SQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNED 827 Query: 85 YCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC---IETQSK 139 +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E + S Sbjct: 828 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSH 887 Query: 140 AMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIFHPMDLC 191 E L L +K ++ + AFQ PVPL PDY + I +PMDL Sbjct: 888 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIKNPMDLS 946 Query: 192 TLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 239 T++K ++ MY E F+AD + I NC +N + +++A IK+ Sbjct: 947 TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 993 >gi|47419909 transcriptional intermediary factor 1 alpha isoform b [Homo sapiens] Length = 1016 Score = 90.9 bits (224), Expect = 6e-18 Identities = 69/230 (30%), Positives = 108/230 (46%), Gaps = 26/230 (11%) Query: 32 SAERTAQKRKFPSPPHSSNGHSP---QDTSTSP----IKKKKKPGLLNSNNKEQDGRNDF 84 S T+++ S S G P QD S++ + +K L +++D N+ Sbjct: 734 SQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNED 793 Query: 85 YCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC---IETQSK 139 +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E + S Sbjct: 794 WCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSH 853 Query: 140 AMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIFHPMDLC 191 E L L +K ++ + AFQ PVPL PDY + I +PMDL Sbjct: 854 NSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIKNPMDLS 912 Query: 192 TLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 239 T++K ++ MY E F+AD + I NC +N + +++A IK+ Sbjct: 913 TIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959 >gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo sapiens] Length = 1110 Score = 89.7 bits (221), Expect = 1e-17 Identities = 60/189 (31%), Positives = 88/189 (46%), Gaps = 15/189 (7%) Query: 72 NSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKIT 129 + NNK+ D D +C VC G +LCCE CP+V+H C L S P GDW C C I Sbjct: 877 DGNNKDDDPNED-WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIG 935 Query: 130 VAEC------IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYA 181 E ++ K T + + + + + FQ+PVP P+Y Sbjct: 936 KPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYY 994 Query: 182 EYIFHPMDLCTLEKNAKKKM---YGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIK 238 + I PMDL T++K +KK Y + F+AD + I NC +N + ++ Q K V Sbjct: 995 KIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVAL 1054 Query: 239 ICEHEMNEI 247 E ++ EI Sbjct: 1055 YFEDKLTEI 1063 >gi|74027249 tripartite motif-containing 33 protein isoform alpha [Homo sapiens] Length = 1127 Score = 80.9 bits (198), Expect = 6e-15 Identities = 54/165 (32%), Positives = 77/165 (46%), Gaps = 15/165 (9%) Query: 72 NSNNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKIT 129 + NNK+ D D +C VC G +LCCE CP+V+H C L S P GDW C C I Sbjct: 877 DGNNKDDDPNED-WCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIG 935 Query: 130 VAEC------IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYA 181 E ++ K T + + + + + FQ+PVP P+Y Sbjct: 936 KPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYY 994 Query: 182 EYIFHPMDLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYN 223 + I PMDL T++K +KK Y + F+AD + I NC +N Sbjct: 995 KIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN 1039 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 80.9 bits (198), Expect = 6e-15 Identities = 127/702 (18%), Positives = 255/702 (36%), Gaps = 14/702 (1%) Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 SD S S +S + + D+ + SS S S +S D D S +S + + + ++ S Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLI 541 S S + + +D + ++ S + N S D + S S ++ Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691 Query: 542 SPKRQIRSRFQLNLDKT-IESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600 S S + D + +S + N S D ++ S+ S SDSSDS S+ Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751 Query: 601 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 660 S + D S+ +N + +S +S+ ++ D Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811 Query: 661 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 720 + + + D D +DS G DSDS + D S Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871 Query: 721 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 780 N + + S + + S + S + S + S+ + ++ S++S+ Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931 Query: 781 TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 840 + + + +++ +S + + + S S+ + S+ Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSN-------SSDSSNSSDSSDSNSSDSSDSSNSSD 984 Query: 841 SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 900 SS SS S + SS ++D ++ S+D + + +S D+ + + +D S + Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042 Query: 901 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELT-MAEMRQSLEQERDRLIAEVKKQ 959 + S ++ + + S+ + + + +E S + ++ Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102 Query: 960 LELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ 1019 + ++ +N + ++S + E S S ++ Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162 Query: 1020 QE-ADAEVNTETLNKS-SQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1077 + +D+ ++++ + S S SS S+ S+ S +S S + S++ S S S+ S Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222 Query: 1078 TPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1119 + SS SN+ SD S S+ SS SS+ S SD + STS Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSS-DSSNSSDSSDSSDSSDSTS 1263 Score = 77.0 bits (188), Expect = 9e-14 Identities = 131/700 (18%), Positives = 258/700 (36%), Gaps = 42/700 (6%) Query: 430 STNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPF 489 S++S+ + SD ++ S S S S D D S +S +S + + S S S K Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630 Query: 490 SPQLSAPITTKTDKTSTTGSILNLNLDRSKAE-----MDLKELSESVQQQSTPVPLISPK 544 S S+ +K+D + + S + N D S + D + S+S S+ S Sbjct: 631 SD--SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688 Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604 S + + + S + ++ S+ + SDS+ S SDSSDS SD Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS--NSSDSDSSNSSDSSDSSNSSDSSDS 746 Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664 S + + S+ ++ + +S +S+ +D D ++ Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806 Query: 665 EPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKN 724 D S+ + D D +DS DS S+ D S R N Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD---GSDSDSSNRSDSSN 863 Query: 725 KKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTA 784 + + S + + S + S + ++ + SS S+ + ++ S+ S+ + + Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923 Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPL 844 + + +++ + +S++ + S ++S + S+ SS Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSD----SSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979 Query: 845 VTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGS 904 SS S + SS ++D ++ S+D + +S D+ + + +D S ++ S Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSD-----SSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034 Query: 905 TIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEK 964 ++ + S+ + + + + D ++ + Sbjct: 1035 DSSD---------------SSDSSDSSDSSDSSDSSNSSDSSDSSDS--SDSSDSSDSSD 1077 Query: 965 QQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADA 1024 E+ +N + ++S + + S S ++ ++ Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137 Query: 1025 EVNTETLNKSSQGSSSS--TQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSI 1082 N+ + SS+ S SS + S+ S +S S + S++ S S S+ S + SS Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197 Query: 1083 LLGSNQGSDHSRSNKSSWSS--SDEKRGSTRSDHNTSTST 1120 S+ SD S S+ SS SS SD S SD N S+ + Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237 Score = 72.4 bits (176), Expect = 2e-12 Identities = 129/706 (18%), Positives = 258/706 (36%), Gaps = 65/706 (9%) Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 SD S S+NSS + S D+ ++SS S S +S D D S +S +S + + S Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAE--MDLKELSESVQQQSTPVP 539 S S S+ + S+ S + + D S + D + S+S + Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770 Query: 540 LISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYIS 599 S S + D + S + + S + + + SDS DS+ S+SSDS S Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830 Query: 600 D--DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGA 657 D D S + + ++ +G D + ++ +S +S +D Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS---------DSSDSSNSSDSSD 881 Query: 658 VKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS 717 D D S+ + S D D +DS +S + S D+S Sbjct: 882 SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS--------DNS 933 Query: 718 GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTS 777 N + + S + ++ S+S + S + +S + ++ +S S Sbjct: 934 NSSDSSNSSDSSDSSDSSN--------SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985 Query: 778 STVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVT 837 S + ++ + ++ S NSS + S S+ Sbjct: 986 SDSSDSSDSSDSSDSS---------------------NSSDSSDSSDSSDSSNSS----D 1020 Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 897 S+ SS SS S + SS ++D ++ S+D + +S D+ + + +D Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----SSNSSDSSDSSDSSDSSDSSDS 1075 Query: 898 SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 957 S ++ S ++ + + S+ + + + + + D ++ Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS--SDSS 1133 Query: 958 KQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATA 1017 + ++ + ++ + ++S ++ + S S ++ Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193 Query: 1018 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETS----AEKSKESGSTLDLS 1073 ++ ++ + SS S SS S S+++ +S E+S + S +S ++ D S Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253 Query: 1074 GSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1119 S ++ S +++ S+S + + SD S SD N STS Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299 Score = 70.5 bits (171), Expect = 9e-12 Identities = 99/546 (18%), Positives = 203/546 (37%), Gaps = 30/546 (5%) Query: 582 SDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKE 641 SDS DS+ SDSS+S SD ++ + D + D S+ +N + + Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606 Query: 642 ELKSTSPASEKADPGAVKDKASPEPE-KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGL 700 S+ + + D + E + D K+ S D D +DS Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666 Query: 701 DSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTR 760 DS S+ D S N + + S + + S + S S + Sbjct: 667 DSSDSSD-----SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721 Query: 761 SSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQ 820 +S+ + ++ ++ ++ +S++ + + ++ S ++S+ Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--------------SNSSDS 767 Query: 821 QKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880 S S+ + S SS SS S ++ SS ++D ++ S+D + + +S Sbjct: 768 SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827 Query: 881 KMMDAIKGTMTEIYNDLSKNTTGSTIAEIRR-----LRIEIEKLQWLHQQELSEMKHNLE 935 D+ + + +D S ++ GS R + + + S+ + E Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887 Query: 936 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995 + + D ++ + ++ + +N + N+S Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES---SNSSDNSNSSDSSNSSDS 944 Query: 996 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKS-SQGSSSSTQSAPSETASASK 1054 ++ + S S ++ ++++ ++++ N S S SS S+ S+ S +S S Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004 Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1114 + S++ S S S+ + S + SS S+ SD S S+ SS SSD S SD Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDS 1063 Query: 1115 NTSTST 1120 + S+ + Sbjct: 1064 SDSSDS 1069 Score = 60.1 bits (144), Expect = 1e-08 Identities = 104/563 (18%), Positives = 206/563 (36%), Gaps = 44/563 (7%) Query: 563 KAQLGINEISEDVYTAVEHSDSE-DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMD 621 K+ G + S D + ++SE D+ S D+ Y SD+ + + N D +G + D Sbjct: 458 KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG----SDSKGAEDD 513 Query: 622 KEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681 S TN + + + ++K+D G K +S D S + S Sbjct: 514 DSDST-----SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD 568 Query: 682 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGR--KNKKEPKEPSPKQDVVG 739 D +DS + DSDS D + + + + + + S D Sbjct: 569 SDSSDSNSSSDSDSS----DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624 Query: 740 KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799 + S + S S ++ +S+ +S ++ +S SS + ++ + ++ S Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684 Query: 800 LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859 NSS + + S S+ S+ SS +S S S+ +S + Sbjct: 685 ---------------NSSDSSDSSDSSNSSESS----DSSDSSDSDSSDSSDSSNSNSSD 725 Query: 860 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919 +D ++ S+D +S D+ + + +D S ++ S ++ + Sbjct: 726 SDSSNSSDSSD--------SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 920 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979 + + ++ ++ + + + D + + + +N Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837 Query: 980 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039 + + S D + S + ++ +D+ + E+ N S S Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897 Query: 1040 SSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSS 1099 S++ + S +S S + S+ S S S+ S + SS S+ SD S S+ SS Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957 Query: 1100 WSSSDEKRGSTRSDHNTSTSTKS 1122 +SSD S SD N+S S+ S Sbjct: 958 -NSSDSSNSSDSSDSNSSDSSDS 979 Score = 33.5 bits (75), Expect = 1.2 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 15/115 (13%) Query: 1023 DAEVNTETLNKSSQGSSSSTQSAPSETASASK-EKETSAEKSKESGSTLDLSGSRETPSS 1081 D + + N S + + + ++ S+ S+S+ + ++++SK++G+ D G+ + S Sbjct: 457 DKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD 516 Query: 1082 ILL----------GSNQGSDHSRSN----KSSWSSSDEKRGSTRSDHNTSTSTKS 1122 G+N D+ +S+ KS S SD S SD + S+ + S Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571 >gi|38788260 bromodomain PHD finger transcription factor isoform 2 [Homo sapiens] Length = 2903 Score = 74.7 bits (182), Expect = 5e-13 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 17/202 (8%) Query: 43 PSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVC---HREGQV-LCC 98 P+ P +S ++ S K KKK ++++ +KE YC +C + E + + C Sbjct: 2685 PTLPAASQKRKREEEKDSSSKSKKKK-MISTTSKETKKDTKLYC-ICKTPYDESKFYIGC 2742 Query: 99 ELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK- 154 + C YH +C+ L SE E ++ CP+C+ A + T +T E L +L+ Sbjct: 2743 DRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLRS 2799 Query: 155 FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKW 214 KM P F +PV PDY I PMDL T+E+ +++ Y F+AD Sbjct: 2800 LQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2855 Query: 215 ILHNCIIYNGGNHKLTQIAKVV 236 I NC YN + Q A+V+ Sbjct: 2856 IFDNCRYYNPSDSPFYQCAEVL 2877 Score = 55.5 bits (132), Expect = 3e-07 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 83 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 137 D +C VCH+ G +LCCE C VYH +C++ L PE +W C C K+ V +C+ Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449 Query: 138 SKAMTMLTIEQLSY 151 K + E + Y Sbjct: 450 QKNKPYIRHEPIGY 463 Score = 37.7 bits (86), Expect = 0.062 Identities = 52/238 (21%), Positives = 95/238 (39%), Gaps = 15/238 (6%) Query: 715 DHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATT 774 ++ ++ KN++E ++ S ++D KTP S T V + ++ ++ G T Sbjct: 584 ENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTN 643 Query: 775 STSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTIT 834 +TS T+P+ + + P +++ ++ V + E S+ T Sbjct: 644 ATSEE---TSPSEGRSPVGCLSETP----DSSNMAEKKVASELPQDVPEEPNKTCESSNT 696 Query: 835 LVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIY 894 T+T P + +S S S L SS + A + + S + + +E Sbjct: 697 SATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKS 756 Query: 895 N-DLS------KNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSL 945 N +LS K +GST I RLR KL L Q+++ H E ++ L Sbjct: 757 NGELSESPGAGKGASGST-RIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVL 813 Score = 37.0 bits (84), Expect = 0.11 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%) Query: 635 NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 690 N E K L S+S A G +D P E D ++ PS P + + ++ Sbjct: 1605 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1659 Query: 691 TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 744 + T + + S+ ES L D D +G KN+ E K + T + Sbjct: 1660 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1718 Query: 745 TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 802 +TV + S V + + +S +T T++T TVT + +TG V Sbjct: 1719 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1771 Query: 803 KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 862 + V S TV +T S +T+ TLVTS V+ S V + Sbjct: 1772 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1821 Query: 863 PIATASADVAADIAKYTSK 881 P T S K+ +K Sbjct: 1822 PKKTRSGTALPSYRKFVTK 1840 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 74.7 bits (182), Expect = 5e-13 Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 17/202 (8%) Query: 43 PSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVC---HREGQV-LCC 98 P+ P +S ++ S K KKK ++++ +KE YC +C + E + + C Sbjct: 2702 PTLPAASQKRKREEEKDSSSKSKKKK-MISTTSKETKKDTKLYC-ICKTPYDESKFYIGC 2759 Query: 99 ELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK- 154 + C YH +C+ L SE E ++ CP+C+ A + T +T E L +L+ Sbjct: 2760 DRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLRS 2816 Query: 155 FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKW 214 KM P F +PV PDY I PMDL T+E+ +++ Y F+AD Sbjct: 2817 LQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK 2872 Query: 215 ILHNCIIYNGGNHKLTQIAKVV 236 I NC YN + Q A+V+ Sbjct: 2873 IFDNCRYYNPSDSPFYQCAEVL 2894 Score = 55.5 bits (132), Expect = 3e-07 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 83 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 137 D +C VCH+ G +LCCE C VYH +C++ L PE +W C C K+ V +C+ Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449 Query: 138 SKAMTMLTIEQLSY 151 K + E + Y Sbjct: 450 QKNKPYIRHEPIGY 463 Score = 46.2 bits (108), Expect = 2e-04 Identities = 51/258 (19%), Positives = 104/258 (40%), Gaps = 16/258 (6%) Query: 727 EPKEPS-PKQDVVGKTPPSTTVGSHSPPET-PVLTRSSAQTSAAGATATTSTSSTVTVTA 784 +P+ P+ P+ + TTV SH P E P +SS AA + ++ V Sbjct: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRV 2343 Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST----VQQKEITQSPSTSTITLVTSTQ 840 +P+ T + RP P + +P Q V +++ +Q Q PS Q Sbjct: 2344 QSPSQT-----RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398 Query: 841 SSPLVTSSG---SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 897 SS SSG + T+ S L I V A + + + +++ + Sbjct: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIA--VPQLQQQVQVLSQIQSQVVAQI 2456 Query: 898 SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 957 +G +L I+I++ + ++ + ++ E Q ++Q RD+ + + Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516 Query: 958 KQLELEKQQAVDETKKKQ 975 +Q+E++++ + + + + Sbjct: 2517 QQIEIKREHTLQASNQSE 2534 Score = 37.0 bits (84), Expect = 0.11 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%) Query: 635 NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 690 N E K L S+S A G +D P E D ++ PS P + + ++ Sbjct: 1479 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1533 Query: 691 TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 744 + T + + S+ ES L D D +G KN+ E K + T + Sbjct: 1534 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1592 Query: 745 TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 802 +TV + S V + + +S +T T++T TVT + +TG V Sbjct: 1593 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1645 Query: 803 KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 862 + V S TV +T S +T+ TLVTS V+ S V + Sbjct: 1646 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1695 Query: 863 PIATASADVAADIAKYTSK 881 P T S K+ +K Sbjct: 1696 PKKTRSGTALPSYRKFVTK 1714 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 71.2 bits (173), Expect = 5e-12 Identities = 124/605 (20%), Positives = 229/605 (37%), Gaps = 66/605 (10%) Query: 538 VPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEY 597 +P +S +++S ++ + + E K + + E +E+ E ++ E+ E + E Sbjct: 429 IPSVSTHIKVKSEEKIKVVEKSE--KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486 Query: 598 ISDDEQKSKNEPEDTED---KEGCQMDKE-----------PSAVK--KKPKPTNPVEIKE 641 +E++++ E+T+ +E +KE P+ K +K + +P E+K Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546 Query: 642 ELKSTSPASEKADPGAVKDKASPE---PEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL 698 K+ SPA E+A K+ PE PEK+ ++ P K K K+E SP Sbjct: 547 PEKAKSPAKEEA-------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA--- 596 Query: 699 GLDSDSESELVIDLGEDHSGREGRKN--KKEPKEPSP-KQDVVGKTPPSTTVGSHSPPET 755 ++ S + + E+ K+ K+E K P+ K K+P S ++ Sbjct: 597 --EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654 Query: 756 PVLTRSSAQTSA-----AGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ 810 P + + A A A + S V A +P SPVK++ K +P + Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714 Query: 811 RVVWNSSTVQQ-KEITQSPSTSTITLVTSTQSSPLVTSSGSMSTL-VSSVNADLPIATAS 868 KE ++P + + +S S TL V S A P A Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP---AK 771 Query: 869 ADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRL-RIEIEKLQWLHQQEL 927 + + K+ K +K + S S + E + EI K + + Sbjct: 772 EEARSPADKFPEKAKSPVKEEVK------SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825 Query: 928 SEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFY 987 E K E+ + E + E+E+ + +++ + +K++A + K K+ A+ Sbjct: 826 EEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE- 883 Query: 988 CCWNTSYCDYPCQQAHWPEHMKSCTQSATAP-----QQEADAEVNTETLNKSSQGSSSST 1042 ++ + K T AP +++A + TE K + + Sbjct: 884 ---KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940 Query: 1043 QSAPSETASASKE-KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS 1101 S P+E A+ E K+T EK+K+ + L S + S S Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL--SKEPSKPKAEKAEKSS 998 Query: 1102 SSDEK 1106 S+D+K Sbjct: 999 STDQK 1003 Score = 48.5 bits (114), Expect = 4e-05 Identities = 70/399 (17%), Positives = 147/399 (36%), Gaps = 39/399 (9%) Query: 376 PTNPSAGT-AKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSS 434 P PS T K+ +EK+K+ + + +++ + ++ + + Sbjct: 427 PKIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485 Query: 435 VHTGSDVEQDAEKKATSSH-----FSASEESMDFLDKSTASPASTKT---------GQAG 480 G + E + ++ T S S +E+ + + SPA K+ + Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545 Query: 481 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 540 S + P + +P K+ + S + KA+ KE ++S + +P Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEKA 604 Query: 541 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 600 SP ++ E K+ + S + + +++ EK+ S + E Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVK--SPEKAKSPTKEEAKSPEKAKSPEKE---- 658 Query: 601 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVE--IKEELKSTSPASEKADPGAV 658 E KS + + E +K S VK + K + +KEE KS A A Sbjct: 659 -EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717 Query: 659 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 718 + + P K+ ++ + + P+K++ K ++ SP E +D+ + Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP----------EKAKTLDVKSPEAK 767 Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPV 757 ++ + P + P++ K+P V S ++P+ Sbjct: 768 TPAKEEARSPADKFPEK---AKSPVKEEVKSPEKAKSPL 803 Score = 45.1 bits (105), Expect = 4e-04 Identities = 64/324 (19%), Positives = 123/324 (37%), Gaps = 17/324 (5%) Query: 426 RSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGS 485 +SP S S +++A+ A + + E++ + + SPA K+ Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAK---SPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629 Query: 486 PKPFSPQLSAPITTKTDKTSTTGSILNLNLDRS--KAEMDLKELSESVQQQSTPVPLISP 543 + SP+ + T + K+ +S KA+ +K ++S ++ +PV + Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689 Query: 544 KRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ 603 + K+ E K+ + S + + +++ EK+ S E E+ Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749 Query: 604 KSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKAS 663 E T D + + + P P + K +K + EKA +D + Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809 Query: 664 PE---PEKD-----FSEKAKPSPHPIKDKLKGKDETDSP-TVHLGLDSDSESELVIDLGE 714 PE P+K+ E+ KP +K+ K +E +P T DS+ E + + Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE---EAPK 866 Query: 715 DHSGREGRKNKKEPKEPSPKQDVV 738 + + + KKEP PK+ V Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKV 890 Score = 38.1 bits (87), Expect = 0.048 Identities = 70/322 (21%), Positives = 123/322 (38%), Gaps = 25/322 (7%) Query: 426 RSPMSTNSSVH----TGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 +SP S V T + +++A S + S E LD SP + + + Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD--VKSPEAKTPAKEEA 774 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSES-VQQQSTP--V 538 S + K F + +P+ + S L + + E+ KE +S V+++ P V Sbjct: 775 RSPADK-FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833 Query: 539 PLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYI 598 + P ++ KT E ++ E VE EK S E Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893 Query: 599 SDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAV 658 ++ + K P ++ KE + K+K E+ ++ + A E + P A Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK------TEVAKKEPDDAKAKEPSKP-AE 946 Query: 659 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 718 K +A+PE + EKAK K K + K + D T+ S S+ + E S Sbjct: 947 KKEAAPEKKDTKEEKAKKPEE--KPKTEAKAKEDDKTL-----SKEPSKPKAEKAEKSSS 999 Query: 719 REGRKNKKEPKEPSPKQDVVGK 740 + +K+ K P++ + + GK Sbjct: 1000 TD-QKDSKPPEKATEDKAAKGK 1020 >gi|209977097 tripartite motif-containing 66 [Homo sapiens] Length = 1216 Score = 70.5 bits (171), Expect = 9e-12 Identities = 68/259 (26%), Positives = 107/259 (41%), Gaps = 44/259 (16%) Query: 46 PHSSNGHSPQD---TSTSPIKKKKKPGLLNSNNKEQDGRNDFYCWVCHREGQVLCCELCP 102 P G SP++ +P KK P + N+ +C VC G++LCC+ CP Sbjct: 939 PPEVEGTSPEEHRLIPRTPGAKKGPPAPIE---------NEDFCAVCLNGGELLCCDRCP 989 Query: 103 RVYHAKC--LRLTSEPEGDWFCPECEKITVAE--------CIE----TQSKAMTMLTIEQ 148 +V+H C L S P G+W C C +T E C S ++M ++ Sbjct: 990 KVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKK 1049 Query: 149 LSYL-LKFAIQKMKQPGTDAFQKPV-PLEQHPDYAEYIFHPMDLCTLEKNAKKK---MYG 203 L L + P F +PV PL +H Y + I PMDL + + +KK Y Sbjct: 1050 CEKLVLSLCCNNLSLP----FHEPVSPLARH--YYQIIKRPMDLSIIRRKLQKKDPAHYT 1103 Query: 204 CTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDN 263 E ++D + + NC +N + ++ + + + E + EI PE A ++ D+ Sbjct: 1104 TPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEI--YPEKRFAQPRQEDS 1161 Query: 264 WFCE-----PCSNPHPLVW 277 E CS P W Sbjct: 1162 DSEEVSSESGCSTPQGFPW 1180 Score = 30.4 bits (67), Expect = 10.0 Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 10/96 (10%) Query: 464 LDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTT----GSILNLNLDRSK 519 LDK+TA+ +G+ LS P + Q S+P + TS + + L + L ++ Sbjct: 588 LDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTR 647 Query: 520 AEMDLKELSESVQQ------QSTPVPLISPKRQIRS 549 E L+ +SV Q+ P L +P + + S Sbjct: 648 LERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSS 683 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 68.9 bits (167), Expect = 3e-11 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%) Query: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420 R+P PN + T + +I ++ V N + ++S S S T R+I Sbjct: 94 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 142 Query: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 478 S + + + + +KK T E +D D +P T T Q Sbjct: 143 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 201 Query: 479 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 533 +S SPK P +P+ S P + T K ++ ++ + K+ S ++ Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261 Query: 534 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 593 ++T + ++ K + + + T E + + E + ++ Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321 Query: 594 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 648 E + + EP T K KEP+ K+P PT P E K +P Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381 Query: 649 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 708 + K+ P K+ A P+K P+P K+ + +PT ++ Sbjct: 382 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434 Query: 709 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 765 E + PKEP+P K P TT SP P+ P T SA T Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491 Query: 766 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 811 + TT+ S+ T P+P T P P PKE AP + Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 533 Score = 59.7 bits (143), Expect = 2e-08 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%) Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525 K T P +G +G K +P S TT+ +K ST+ I Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 211 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582 + + P P + P L ++K T+E+ + + S D Sbjct: 212 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 267 Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641 +++ EK+ + D S K + E T KEP+ K+P T P E Sbjct: 268 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 327 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 ++P + K +P K++P K+ P+P K+ + +PT Sbjct: 328 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 375 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 KEP+P T P + P + Sbjct: 376 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817 A T+ T TT T PAP P KK P PKE AP + ++ Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857 T + SP+T T+T+S+P T + +T S+ Sbjct: 470 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504 Score = 53.9 bits (128), Expect = 8e-07 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%) Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665 EP T KE + +A K+P PT P K K +P + K DK +P Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 780 Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721 K+ + P P K ++P T + + ++ I D S E Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840 Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 + + E SPK+ V T +TP T+ T+A T +T Sbjct: 841 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 888 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837 T AP T KETA ++ + T ++T + + T IT + Sbjct: 889 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 936 Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880 +T +P VT++ T +N P TA A +K T+ Sbjct: 937 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 977 Score = 52.4 bits (124), Expect = 2e-06 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%) Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526 +T PA T T A + P P + + AP T K + TT + A KE Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 550 Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586 + + ++ P +PK + + +T + +L + T E Sbjct: 551 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603 Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643 E+ + E + + EP T K KEP+ K+P PT P E Sbjct: 604 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660 Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702 K T+P + K P +K+ A P+K ++ P+ K+ + +PT G Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 718 Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762 + PKEP+P K P TT +P ++ Sbjct: 719 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 752 Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822 + A A T+T + T+ PA T K+ P PKE AP + Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 805 Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882 T P+TS ++ T+T+ + S ST S P A + + T+K Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 862 Query: 883 MDAIKGTMTEIYND 896 A K MT D Sbjct: 863 PAATKPEMTTTAKD 876 Score = 48.5 bits (114), Expect = 4e-05 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%) Query: 446 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 505 ++ ++SS S+S ++ + S S A+ + + + + K + + P D+ Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 182 Query: 506 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 565 + LD ++ + S + + + P I+ + I R L + Sbjct: 183 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 226 Query: 566 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 624 ++ S++ V + +++++ +++ + +D ++K+ + E ++ D P Sbjct: 227 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283 Query: 625 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681 S V KP P K E + PA ++ P K+ AS P++ P+P I Sbjct: 284 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 330 Query: 682 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 741 K +PT PKEP+P T Sbjct: 331 KS---------APTT-------------------------------PKEPAPTTTKSAPT 350 Query: 742 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 801 P + + P + A T+ TT+ S+ T PAP KK P Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 406 Query: 802 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 832 PKE AP + ++ + T+ P+ +T Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437 Score = 47.0 bits (110), Expect = 1e-04 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%) Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421 T T + Q D + + EK D+ + K+L +KP T + Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 302 Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 P+ P T + ++ S+ + E + +T S +T A + Sbjct: 303 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 358 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535 + P P +P+ AP TTK +TT S + + A KE + + ++ Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418 Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591 TP P + + + + E T + + E S + Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478 Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638 + + + EP T K KEPS K+P PT P E Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538 Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691 +E T+P ++K P K+ A P++ K +KL E Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598 Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739 +PT L + E E+ + + KEP +PK+ Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658 Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 K P TT +P E T ++ A T+ T Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841 T PA T K+ P PK TAP +T+++ T + L +T Sbjct: 719 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 767 Query: 842 SPLVTSS 848 P T+S Sbjct: 768 GPTSTTS 774 Score = 42.0 bits (97), Expect = 0.003 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%) Query: 624 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 683 P + KK P P+ + +KST+ S K P K K E E + +E+ S + ++ Sbjct: 72 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 124 Query: 684 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 743 + S + + S S +L + ++ +KN+ + K+P+PK VV + Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 183 Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803 G T TST+ V+ T P+ RP LP Sbjct: 184 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 225 Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 863 + + + S TV ++ ++ T+T TST TS+ ++ + DL Sbjct: 226 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 280 Query: 864 IATASADVAADIAKYTSKMMDAIKG 888 A + +AK T K KG Sbjct: 281 -----APTSKVLAKPTPKAETTTKG 300 Score = 38.1 bits (87), Expect = 0.048 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%) Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484 P +P T S V T + K+ T+ H S E + + +A P + G Sbjct: 806 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 856 Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544 P +P + P T T K TT L + + A + + + + +++T + + Sbjct: 857 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916 Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604 Q+ S T L ++ V T K + +E + Sbjct: 917 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 957 Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664 N+PE+T + D+ ++ PKP P K K TS K P K K +P Sbjct: 958 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1009 Query: 665 EPEKDFSEKAKPSP 678 P K S + +P Sbjct: 1010 TPRKMTSTMPELNP 1023 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 68.9 bits (167), Expect = 3e-11 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%) Query: 361 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 420 R+P PN + T + +I ++ V N + ++S S S T R+I Sbjct: 135 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 183 Query: 421 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 478 S + + + + +KK T E +D D +P T T Q Sbjct: 184 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 242 Query: 479 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 533 +S SPK P +P+ S P + T K ++ ++ + K+ S ++ Sbjct: 243 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302 Query: 534 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 593 ++T + ++ K + + + T E + + E + ++ Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362 Query: 594 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 648 E + + EP T K KEP+ K+P PT P E K +P Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422 Query: 649 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 708 + K+ P K+ A P+K P+P K+ + +PT ++ Sbjct: 423 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475 Query: 709 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 765 E + PKEP+P K P TT SP P+ P T SA T Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532 Query: 766 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 811 + TT+ S+ T P+P T P P PKE AP + Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 574 Score = 59.7 bits (143), Expect = 2e-08 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%) Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525 K T P +G +G K +P S TT+ +K ST+ I Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 252 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582 + + P P + P L ++K T+E+ + + S D Sbjct: 253 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 308 Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641 +++ EK+ + D S K + E T KEP+ K+P T P E Sbjct: 309 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 368 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 ++P + K +P K++P K+ P+P K+ + +PT Sbjct: 369 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 416 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 KEP+P T P + P + Sbjct: 417 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817 A T+ T TT T PAP P KK P PKE AP + ++ Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857 T + SP+T T+T+S+P T + +T S+ Sbjct: 511 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545 Score = 53.9 bits (128), Expect = 8e-07 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%) Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665 EP T KE + +A K+P PT P K K +P + K DK +P Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 821 Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721 K+ + P P K ++P T + + ++ I D S E Sbjct: 822 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881 Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 + + E SPK+ V T +TP T+ T+A T +T Sbjct: 882 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 929 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837 T AP T KETA ++ + T ++T + + T IT + Sbjct: 930 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 977 Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880 +T +P VT++ T +N P TA A +K T+ Sbjct: 978 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 1018 Score = 52.4 bits (124), Expect = 2e-06 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%) Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526 +T PA T T A + P P + + AP T K + TT + A KE Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 591 Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586 + + ++ P +PK + + +T + +L + T E Sbjct: 592 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644 Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643 E+ + E + + EP T K KEP+ K+P PT P E Sbjct: 645 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701 Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702 K T+P + K P +K+ A P+K ++ P+ K+ + +PT G Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 759 Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762 + PKEP+P K P TT +P ++ Sbjct: 760 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 793 Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822 + A A T+T + T+ PA T K+ P PKE AP + Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 846 Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882 T P+TS ++ T+T+ + S ST S P A + + T+K Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 903 Query: 883 MDAIKGTMTEIYND 896 A K MT D Sbjct: 904 PAATKPEMTTTAKD 917 Score = 48.5 bits (114), Expect = 4e-05 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%) Query: 446 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 505 ++ ++SS S+S ++ + S S A+ + + + + K + + P D+ Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 223 Query: 506 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 565 + LD ++ + S + + + P I+ + I R L + Sbjct: 224 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 267 Query: 566 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 624 ++ S++ V + +++++ +++ + +D ++K+ + E ++ D P Sbjct: 268 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324 Query: 625 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 681 S V KP P K E + PA ++ P K+ AS P++ P+P I Sbjct: 325 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 371 Query: 682 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 741 K +PT PKEP+P T Sbjct: 372 KS---------APTT-------------------------------PKEPAPTTTKSAPT 391 Query: 742 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 801 P + + P + A T+ TT+ S+ T PAP KK P Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 447 Query: 802 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 832 PKE AP + ++ + T+ P+ +T Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478 Score = 47.0 bits (110), Expect = 1e-04 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%) Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421 T T + Q D + + EK D+ + K+L +KP T + Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 343 Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 P+ P T + ++ S+ + E + +T S +T A + Sbjct: 344 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 399 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535 + P P +P+ AP TTK +TT S + + A KE + + ++ Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459 Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591 TP P + + + + E T + + E S + Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519 Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638 + + + EP T K KEPS K+P PT P E Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579 Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691 +E T+P ++K P K+ A P++ K +KL E Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639 Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739 +PT L + E E+ + + KEP +PK+ Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699 Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 K P TT +P E T ++ A T+ T Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841 T PA T K+ P PK TAP +T+++ T + L +T Sbjct: 760 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 808 Query: 842 SPLVTSS 848 P T+S Sbjct: 809 GPTSTTS 815 Score = 42.0 bits (97), Expect = 0.003 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%) Query: 624 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 683 P + KK P P+ + +KST+ S K P K K E E + +E+ S + ++ Sbjct: 113 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 165 Query: 684 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 743 + S + + S S +L + ++ +KN+ + K+P+PK VV + Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 224 Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803 G T TST+ V+ T P+ RP LP Sbjct: 225 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 266 Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 863 + + + S TV ++ ++ T+T TST TS+ ++ + DL Sbjct: 267 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 321 Query: 864 IATASADVAADIAKYTSKMMDAIKG 888 A + +AK T K KG Sbjct: 322 -----APTSKVLAKPTPKAETTTKG 341 Score = 38.1 bits (87), Expect = 0.048 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%) Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484 P +P T S V T + K+ T+ H S E + + +A P + G Sbjct: 847 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 897 Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544 P +P + P T T K TT L + + A + + + + +++T + + Sbjct: 898 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957 Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604 Q+ S T L ++ V T K + +E + Sbjct: 958 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 998 Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664 N+PE+T + D+ ++ PKP P K K TS K P K K +P Sbjct: 999 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1050 Query: 665 EPEKDFSEKAKPSP 678 P K S + +P Sbjct: 1051 TPRKMTSTMPELNP 1064 >gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] Length = 1872 Score = 68.2 bits (165), Expect = 4e-11 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%) Query: 149 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207 LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444 Query: 208 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 F + I+ N YNG H LTQI++ ++ +C+ ++ E E Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485 Score = 62.4 bits (150), Expect = 2e-09 Identities = 32/89 (35%), Positives = 47/89 (52%) Query: 160 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219 M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N Sbjct: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579 Query: 220 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 + YNG + T+ A+ ++ +C + E + Sbjct: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608 >gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] Length = 1893 Score = 68.2 bits (165), Expect = 4e-11 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%) Query: 149 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207 LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465 Query: 208 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 F + I+ N YNG H LTQI++ ++ +C+ ++ E E Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1506 Score = 62.4 bits (150), Expect = 2e-09 Identities = 32/89 (35%), Positives = 47/89 (52%) Query: 160 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219 M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N Sbjct: 1541 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1600 Query: 220 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 + YNG + T+ A+ ++ +C + E + Sbjct: 1601 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1629 >gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sapiens] Length = 1826 Score = 67.0 bits (162), Expect = 1e-10 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Query: 149 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 207 LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K +Y E Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463 Query: 208 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 F + I+ N YNG H LTQI++ ++ +C+ ++ E E Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504 Score = 60.8 bits (146), Expect = 7e-09 Identities = 32/89 (35%), Positives = 47/89 (52%) Query: 160 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 219 M P + F PV + PDY + I +P+DL T+ KN K Y E+FL D IL N Sbjct: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598 Query: 220 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 248 + YNG + T+ A+ ++ IC + E + Sbjct: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 65.5 bits (158), Expect = 3e-10 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%) Query: 440 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 492 D +++ KK + +E+ LD + T T Q +S SPK P +P+ Sbjct: 68 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127 Query: 493 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 552 S P + T K ++ ++ + K+ S ++++T + ++ Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187 Query: 553 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 609 K + + + T E + + E + ++ E + + EP Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247 Query: 610 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 667 T K KEP+ K+P PT P E K +P + K+ P K+ A P+ Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307 Query: 668 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 727 K P+P K+ + +PT ++ E + Sbjct: 308 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360 Query: 728 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 784 PKEP+P K P TT SP P+ P T SA T+ TT+ S+ T Sbjct: 361 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417 Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQR 811 P+P T P P PKE AP + Sbjct: 418 PSPTTTKEPA----PTTPKEPAPTTPK 440 Score = 59.7 bits (143), Expect = 2e-08 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%) Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525 K T P +G +G K +P S TT+ +K ST+ I Sbjct: 77 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 118 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582 + + P P + P L ++K T+E+ + + S D Sbjct: 119 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 174 Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641 +++ EK+ + D S K + E T KEP+ K+P T P E Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 ++P + K +P K++P K+ P+P K+ + +PT Sbjct: 235 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 282 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 KEP+P T P + P + Sbjct: 283 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817 A T+ T TT T PAP P KK P PKE AP + ++ Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376 Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857 T + SP+T T+T+S+P T + +T S+ Sbjct: 377 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411 Score = 53.9 bits (128), Expect = 8e-07 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%) Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665 EP T KE + +A K+P PT P K K +P + K DK +P Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 687 Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721 K+ + P P K ++P T + + ++ I D S E Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747 Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 + + E SPK+ V T +TP T+ T+A T +T Sbjct: 748 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 795 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837 T AP T KETA ++ + T ++T + + T IT + Sbjct: 796 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 843 Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880 +T +P VT++ T +N P TA A +K T+ Sbjct: 844 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 884 Score = 52.4 bits (124), Expect = 2e-06 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%) Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526 +T PA T T A + P P + + AP T K + TT + A KE Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 457 Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586 + + ++ P +PK + + +T + +L + T E Sbjct: 458 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510 Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643 E+ + E + + EP T K KEP+ K+P PT P E Sbjct: 511 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567 Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702 K T+P + K P +K+ A P+K ++ P+ K+ + +PT G Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 625 Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762 + PKEP+P K P TT +P ++ Sbjct: 626 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 659 Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822 + A A T+T + T+ PA T K+ P PKE AP + Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 712 Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882 T P+TS ++ T+T+ + S ST S P A + + T+K Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 769 Query: 883 MDAIKGTMTEIYND 896 A K MT D Sbjct: 770 PAATKPEMTTTAKD 783 Score = 47.0 bits (110), Expect = 1e-04 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%) Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421 T T + Q D + + EK D+ + K+L +KP T + Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 209 Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 P+ P T + ++ S+ + E + +T S +T A + Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 265 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535 + P P +P+ AP TTK +TT S + + A KE + + ++ Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325 Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591 TP P + + + + E T + + E S + Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385 Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638 + + + EP T K KEPS K+P PT P E Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445 Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691 +E T+P ++K P K+ A P++ K +KL E Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505 Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739 +PT L + E E+ + + KEP +PK+ Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565 Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 K P TT +P E T ++ A T+ T Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841 T PA T K+ P PK TAP +T+++ T + L +T Sbjct: 626 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 674 Query: 842 SPLVTSS 848 P T+S Sbjct: 675 GPTSTTS 681 Score = 38.1 bits (87), Expect = 0.048 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%) Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484 P +P T S V T + K+ T+ H S E + + +A P + G Sbjct: 713 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 763 Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544 P +P + P T T K TT L + + A + + + + +++T + + Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823 Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604 Q+ S T L ++ V T K + +E + Sbjct: 824 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 864 Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664 N+PE+T + D+ ++ PKP P K K TS K P K K +P Sbjct: 865 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 916 Query: 665 EPEKDFSEKAKPSP 678 P K S + +P Sbjct: 917 TPRKMTSTMPELNP 930 Score = 33.5 bits (75), Expect = 1.2 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%) Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 778 ++ +KN+ + K+P+PK VV + G T TST+ Sbjct: 67 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 108 Query: 779 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 838 V+ T P+ RP LP + + + S TV ++ ++ T+T TS Sbjct: 109 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 163 Query: 839 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 888 T TS+ ++ + DL A + +AK T K KG Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 207 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 65.5 bits (158), Expect = 3e-10 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%) Query: 440 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 492 D +++ KK + +E+ LD + T T Q +S SPK P +P+ Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168 Query: 493 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 552 S P + T K ++ ++ + K+ S ++++T + ++ Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228 Query: 553 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 609 K + + + T E + + E + ++ E + + EP Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288 Query: 610 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 667 T K KEP+ K+P PT P E K +P + K+ P K+ A P+ Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348 Query: 668 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 727 K P+P K+ + +PT ++ E + Sbjct: 349 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401 Query: 728 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 784 PKEP+P K P TT SP P+ P T SA T+ TT+ S+ T Sbjct: 402 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458 Query: 785 PAPAATGSPVKKQRPLLPKETAPAVQR 811 P+P T P P PKE AP + Sbjct: 459 PSPTTTKEPA----PTTPKEPAPTTPK 481 Score = 59.7 bits (143), Expect = 2e-08 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%) Query: 466 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 525 K T P +G +G K +P S TT+ +K ST+ I Sbjct: 118 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 159 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 582 + + P P + P L ++K T+E+ + + S D Sbjct: 160 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 215 Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 641 +++ EK+ + D S K + E T KEP+ K+P T P E Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 ++P + K +P K++P K+ P+P K+ + +PT Sbjct: 276 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 323 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 KEP+P T P + P + Sbjct: 324 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 817 A T+ T TT T PAP P KK P PKE AP + ++ Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417 Query: 818 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 857 T + SP+T T+T+S+P T + +T S+ Sbjct: 418 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452 Score = 53.9 bits (128), Expect = 8e-07 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%) Query: 608 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 665 EP T KE + +A K+P PT P K K +P + K DK +P Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 728 Query: 666 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 721 K+ + P P K ++P T + + ++ I D S E Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788 Query: 722 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 + + E SPK+ V T +TP T+ T+A T +T Sbjct: 789 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 836 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 837 T AP T KETA ++ + T ++T + + T IT + Sbjct: 837 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 884 Query: 838 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 880 +T +P VT++ T +N P TA A +K T+ Sbjct: 885 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 925 Score = 52.4 bits (124), Expect = 2e-06 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%) Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 526 +T PA T T A + P P + + AP T K + TT + A KE Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 498 Query: 527 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 586 + + ++ P +PK + + +T + +L + T E Sbjct: 499 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551 Query: 587 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 643 E+ + E + + EP T K KEP+ K+P PT P E Sbjct: 552 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608 Query: 644 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702 K T+P + K P +K+ A P+K ++ P+ K+ + +PT G Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 666 Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762 + PKEP+P K P TT +P ++ Sbjct: 667 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 700 Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822 + A A T+T + T+ PA T K+ P PKE AP + Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 753 Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882 T P+TS ++ T+T+ + S ST S P A + + T+K Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 810 Query: 883 MDAIKGTMTEIYND 896 A K MT D Sbjct: 811 PAATKPEMTTTAKD 824 Score = 47.0 bits (110), Expect = 1e-04 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%) Query: 362 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 421 T T + Q D + + EK D+ + K+L +KP T + Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 250 Query: 422 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 481 P+ P T + ++ S+ + E + +T S +T A + Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 306 Query: 482 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 535 + P P +P+ AP TTK +TT S + + A KE + + ++ Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366 Query: 536 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 591 TP P + + + + E T + + E S + Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426 Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 638 + + + EP T K KEPS K+P PT P E Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486 Query: 639 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 691 +E T+P ++K P K+ A P++ K +KL E Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546 Query: 692 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 739 +PT L + E E+ + + KEP +PK+ Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606 Query: 740 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 781 K P TT +P E T ++ A T+ T Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666 Query: 782 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 841 T PA T K+ P PK TAP +T+++ T + L +T Sbjct: 667 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 715 Query: 842 SPLVTSS 848 P T+S Sbjct: 716 GPTSTTS 722 Score = 38.1 bits (87), Expect = 0.048 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%) Query: 425 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 484 P +P T S V T + K+ T+ H S E + + +A P + G Sbjct: 754 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 804 Query: 485 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 544 P +P + P T T K TT L + + A + + + + +++T + + Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864 Query: 545 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 604 Q+ S T L ++ V T K + +E + Sbjct: 865 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 905 Query: 605 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 664 N+PE+T + D+ ++ PKP P K K TS K P K K +P Sbjct: 906 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 957 Query: 665 EPEKDFSEKAKPSP 678 P K S + +P Sbjct: 958 TPRKMTSTMPELNP 971 Score = 33.5 bits (75), Expect = 1.2 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%) Query: 719 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 778 ++ +KN+ + K+P+PK VV + G T TST+ Sbjct: 108 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 149 Query: 779 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 838 V+ T P+ RP LP + + + S TV ++ ++ T+T TS Sbjct: 150 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 204 Query: 839 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 888 T TS+ ++ + DL A + +AK T K KG Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 248 >gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sapiens] Length = 1912 Score = 63.9 bits (154), Expect = 8e-10 Identities = 33/94 (35%), Positives = 46/94 (48%), Gaps = 16/94 (17%) Query: 48 SSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQDGRNDF------------YCWVCHREGQV 95 S N +S D STS + +K L + K++ G + YC VC + G++ Sbjct: 325 SINSYSVSDGSTSRSSRSRKK--LRTTKKKKKGEEEVTAVDGYETDHQDYCEVCQQGGEI 382 Query: 96 LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127 + C+ CPR YH CL + PEG W CP CEK Sbjct: 383 ILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK 416 Score = 56.2 bits (134), Expect = 2e-07 Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Query: 76 KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125 +E+D + +C VC G++LCC+ CP YH CL L P G+W CP C Sbjct: 442 EEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRC 493 Score = 37.7 bits (86), Expect = 0.062 Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 36/242 (14%) Query: 581 HSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN---PV 637 H ++E+ + D S++E ++K +P D + + + KE + ++ ++ P Sbjct: 32 HPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPE 91 Query: 638 EIKEE----LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDS 693 ++EE L+S S S+ K K P+ EK K K +++ + D+ DS Sbjct: 92 FVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRK------EEEEEEDDDDDS 145 Query: 694 PTVHLGLDSDSESELVIDLG----------EDHSGREGRKNKKEPKEP--SPKQDVVGKT 741 + S ++L+ D G ED+ K + P + K + + Sbjct: 146 K------EPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVS 199 Query: 742 PPSTTVGS---HSPPETPVLTRSSAQTSAAGATATTSTSSTVTVT--APAPAATGSPVKK 796 +G+ P S A +AA A A S VT T AP P P++K Sbjct: 200 KMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRK 259 Query: 797 QR 798 + Sbjct: 260 AK 261 >gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sapiens] Length = 1954 Score = 63.9 bits (154), Expect = 8e-10 Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 7/107 (6%) Query: 26 RSKDPGSAERTAQKRKFPSPP-HSSNGHSPQDTSTSPIKKK--KKPGLLNSNNKEQDGRN 82 R K S E ++ F S HS++ S + K+ KK + + + E D ++ Sbjct: 285 RKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQD 344 Query: 83 DFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127 YC VC + G+++ C+ CPR YH CL L PEG W CP CEK Sbjct: 345 --YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEK 389 Score = 54.7 bits (130), Expect = 5e-07 Identities = 23/52 (44%), Positives = 30/52 (57%), Gaps = 3/52 (5%) Query: 76 KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125 +E+D +F C VC G++LCC+ CP YH CL L P G+W CP C Sbjct: 410 EEEDDHMEF-CRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460 Score = 35.0 bits (79), Expect = 0.40 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 9/124 (7%) Query: 613 EDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASE---KADPGAVKDKASPEPEKD 669 E G Q ++P V+ P + VE ++ K SPAS+ + + +KA P PE+ Sbjct: 1578 EKDPGAQKPRQPLEVQALPAALDRVESED--KHESPASKERAREERPEETEKAPPSPEQL 1635 Query: 670 FSEKAKPSPHPIKDKLKGK---DETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKK 726 E+ P I DKL+ DS + D+ +E + I+ ++ E + KK Sbjct: 1636 PREEVLPEKEKILDKLELSLIHSRGDSSELRPD-DTKAEEKEPIETQQNGDKEEDDEGKK 1694 Query: 727 EPKE 730 E K+ Sbjct: 1695 EDKK 1698 >gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1 [Homo sapiens] Length = 2000 Score = 63.2 bits (152), Expect = 1e-09 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%) Query: 47 HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95 HS++G T +K+ +KK +L + +E DG + YC VC + G++ Sbjct: 332 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 391 Query: 96 LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127 + C+ CPR YH CL L PEG W CP CEK Sbjct: 392 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425 Score = 53.1 bits (126), Expect = 1e-06 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 76 KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125 KE++ + YC VC G++LCC+ C YH CL L P G+W CP C Sbjct: 449 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500 >gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2 [Homo sapiens] Length = 1966 Score = 63.2 bits (152), Expect = 1e-09 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%) Query: 47 HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95 HS++G T +K+ +KK +L + +E DG + YC VC + G++ Sbjct: 332 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 391 Query: 96 LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127 + C+ CPR YH CL L PEG W CP CEK Sbjct: 392 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425 Score = 53.1 bits (126), Expect = 1e-06 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 76 KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125 KE++ + YC VC G++LCC+ C YH CL L P G+W CP C Sbjct: 449 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500 >gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3 [Homo sapiens] Length = 2059 Score = 63.2 bits (152), Expect = 1e-09 Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 13/94 (13%) Query: 47 HSSNGHSPQDTSTSPIKK----KKKPGLLN----SNNKEQDGR---NDFYCWVCHREGQV 95 HS++G T +K+ +KK +L + +E DG + YC VC + G++ Sbjct: 391 HSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEI 450 Query: 96 LCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 127 + C+ CPR YH CL L PEG W CP CEK Sbjct: 451 ILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 484 Score = 53.1 bits (126), Expect = 1e-06 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 2/52 (3%) Query: 76 KEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 125 KE++ + YC VC G++LCC+ C YH CL L P G+W CP C Sbjct: 508 KEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559 Score = 37.4 bits (85), Expect = 0.081 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%) Query: 571 ISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ------KSKNEPEDTEDKEGCQM--DK 622 +SE+ E D E+ E+ +++D + DD++ + D GC + Sbjct: 17 VSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPP 76 Query: 623 EPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIK 682 P P P P K++++ A G K K P+ +K+ KP P K Sbjct: 77 PPPPPPLPPPPPPPPPDKDDIRLLPSAL-----GVKKRKRGPKKQKE----NKPG-KPRK 126 Query: 683 DKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQ 735 K + +E G + D E G ++ GRK +++ +E K+ Sbjct: 127 RKKRDSEE------EFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKK 173 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 62.0 bits (149), Expect = 3e-09 Identities = 82/406 (20%), Positives = 147/406 (36%), Gaps = 26/406 (6%) Query: 717 SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 776 +G E E E + +T +T GS + T T S T+ + A + +T Sbjct: 549 TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605 Query: 777 SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836 +ST + + TGS TA +ST + T S + S T+V Sbjct: 606 ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656 Query: 837 TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 895 ++T S +TS+ GS +T VS+ ++ ++T + + + G+ T I + Sbjct: 657 STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS 716 Query: 896 DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 955 T ++I E + + T +E + + +A Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 956 VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1015 + E + K A+ K +F T+ + S S Sbjct: 777 IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831 Query: 1016 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1075 T P A +E T T + S+ +++ST+ + + TAS + T+A +T GS Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 1076 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1121 T +S ++ S + +S S+ ST T+ ST+ Sbjct: 892 ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 53.9 bits (128), Expect = 8e-07 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%) Query: 415 TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 469 TG + + S M+T S+ TG++ D+ E T++ +A E+ + +TA Sbjct: 549 TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 470 SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 527 S A ++T A S +GS + S+ TT + + S T ++ + + + E + Sbjct: 607 STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 528 SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 587 + + ++T V + + + +I + SE T+ E S+ + Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTA 725 Query: 588 EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 647 + S + ++ + + E +E E + T I T+ Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783 Query: 648 PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 707 AS AS + F+E ++ + + +++ TV + SE+ Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833 Query: 708 LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 G + + G E E E + +T +TT+GS + T T Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 820 S T+ + + T+T+ST + TGS + T + + + ST Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950 Query: 821 QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 879 + IT S S T VT+ S S+ GS +T VS+ ++ A+ ++ Sbjct: 951 SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 880 SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 938 S+ + GT T I + TT T A + + + T Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 939 AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 998 +E + + + A ET ++ T+ Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119 Query: 999 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1054 +A S T +A+ E T ET S+ GS ++T SA T ++++ Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179 Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1111 ET+ + S +T + ET ++ GS + + +++S SS +T Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239 Query: 1112 SDHNTSTSTKSLLPKESRL 1130 T ST SL P + L Sbjct: 1240 GSETTIASTASLEPTATSL 1258 Score = 50.1 bits (118), Expect = 1e-05 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%) Query: 740 KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799 +T ++T GS + +P ++++ + + TTST+ + T + + + Sbjct: 34 ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93 Query: 800 LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859 TA + V S T + + + + T T T++ + + +++GS +T VS+V Sbjct: 94 ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151 Query: 860 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919 ++ A +AD A T MT ++ S+ T ST E + Sbjct: 152 SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197 Query: 920 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979 + + E T A S + +E K + V + A+ Sbjct: 198 STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257 Query: 980 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039 + NT++ E K+ T S T + A + +E S+ GS Sbjct: 258 TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302 Query: 1040 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1086 + ST S+ T A+ + A +T+ +GS T +SI +GS Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361 Query: 1087 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128 +D + ++++ +S++ +T S + +T S E+ Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403 Score = 48.5 bits (114), Expect = 4e-05 Identities = 116/563 (20%), Positives = 190/563 (33%), Gaps = 76/563 (13%) Query: 375 DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 432 D N +A TA + + T + S G +S +D + +ST Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 433 SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS--------- 481 S T + E + AT S + S E S +TK GS Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719 Query: 482 -------LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE-------- 526 ++GS + + TT + + S T S + + A E Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 527 ----LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHS 582 ++ ++ ++T V S K + + F N + TI S A SE T V + Sbjct: 780 SETTMASTIGSETTKVSTASSK--MTTVFTENSETTIASTTA-------SET--TTVSTA 828 Query: 583 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEE 642 SE S + + + S+ TE E E S + T I E Sbjct: 829 GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIGSE 882 Query: 643 LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 702 + S + + + + + SE S + + +++ T S Sbjct: 883 TTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA-----S 937 Query: 703 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 762 SEL +G E E E + + +T ++T GS ET ++ + Sbjct: 938 TEGSELTT---VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS----ETTTVSTAG 990 Query: 763 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 822 ++T+ TA+ S T TV++ TGS + T + + + T Sbjct: 991 SETT----TASIEGSETTTVSS-----TGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041 Query: 823 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 882 E T +T + T TST+ S T S + S ++ ADL T S + T+ Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-- 1099 Query: 883 MDAIKGTMTEIYNDLSKNTTGST 905 T +Y SK TT ST Sbjct: 1100 ----GSETTTVYITGSKTTTAST 1118 Score = 46.2 bits (108), Expect = 2e-04 Identities = 133/752 (17%), Positives = 262/752 (34%), Gaps = 87/752 (11%) Query: 409 PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 468 P +G +S + + +ST S T + A + T++ SE + K + Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238 Query: 469 ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 528 + + T AGS + + + + T D +TT S + ++ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296 Query: 529 ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 588 ++ ++T I P+ S + + + + + + T V + SE + Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355 Query: 589 KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 645 S SE +D S+ TE E E S V T V I + ++ Sbjct: 356 ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413 Query: 646 TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 703 T+ +E ++ AV + + SE S + + +++ TV + Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470 Query: 704 SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 751 SE++ G + ++G E G E S V TTV + Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530 Query: 752 PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 807 T V T S T+ + T+T+ST +T + A T + + TA Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590 Query: 808 AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 859 + V + ++ E T + +T + T ST SS T+S GS +T VS+ + Sbjct: 591 SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650 Query: 860 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919 ++ + + + + S+ T++ ++ + +T GS + E K+ Sbjct: 651 SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705 Query: 920 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979 + E+T A + S + A + ET + Sbjct: 706 STTGSETTITSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760 Query: 980 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039 ++ T S T+ + + + +ET S+ GS Sbjct: 761 -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791 Query: 1040 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1096 + ST S+ T + T A + +T+ +GS P+S + + + Sbjct: 792 TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851 Query: 1097 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128 +++ +S++ +T S ++ T+T + + E+ Sbjct: 852 ETTTASTEGSETTTASTESSETTTATTIGSET 883 Score = 44.7 bits (104), Expect = 5e-04 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%) Query: 735 QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 794 + V TT S + ET +++ ++T+ +TTS+ +TVT TA + T S V Sbjct: 94 ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150 Query: 795 KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 851 + ET A S+T + + + TIT T+ + V+++GS Sbjct: 151 GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203 Query: 852 STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 907 +T VS+ ++ A+ + A+ + T+K+ A G+ T + S+ T ST + Sbjct: 204 TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261 Query: 908 EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 967 E E K + E T A S + + + + + Sbjct: 262 ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310 Query: 968 VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1025 + TK A+ + +F T + S T +A+ + D+ Sbjct: 311 PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368 Query: 1026 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1080 +ET S++GS ++ST+ + + T S + + T+ + +T GS T + Sbjct: 369 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428 Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1120 ++ + ++ S +S S S+ ST T+ +T Sbjct: 429 TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468 Score = 37.0 bits (84), Expect = 0.11 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%) Query: 407 SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 466 S+ + TG + + S + S + + + + + T ++S+ + F + Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809 Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 525 S + AST + ++S + P +A T T TST GS + + S+ Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 585 E SE+ +T + S + + E + E SE T V + SE Sbjct: 869 ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922 Query: 586 DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 641 + S + SE + + S+ T E + E S + T Sbjct: 923 TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 E + S A + +++ + SE S + + + +++ TV Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 759 + SE+ V G + + ++ + + T +TTV + T T Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 760 RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 819 S T+ + T+T+ST A + T S + T V V ++TV Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156 Query: 820 QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 868 E T S + + TST+ S T+S GS +T S+ ++ A+ S Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209 Score = 33.9 bits (76), Expect = 0.90 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%) Query: 738 VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 790 V +T +T+GS + T T S T+A+ A + T+T+ST + + Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209 Query: 791 GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 847 GS + + P+ N++ + E T + + S T T +T ++++ + + Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269 Query: 848 SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 893 + + ++V++ + T + DV+ I T+ M + T T + Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313 Score = 33.9 bits (76), Expect = 0.90 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%) Query: 704 SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 750 SE+ V +G + + G E E E + +T ++T GS Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 751 SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 796 S T T S T ++ + T T+ +ST ++ A + TGS + Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270 Query: 797 QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 856 T + V+ ++ V + IT +P + T T T +S VT + M S Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330 Query: 857 SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 905 + + +P I TS + + G + + TTGST Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369 Score = 30.4 bits (67), Expect = 10.0 Identities = 43/185 (23%), Positives = 68/185 (36%), Gaps = 7/185 (3%) Query: 721 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQT--SAAGATATTSTS- 777 G K E S V + +TT + T V T S T S G+ ATTS++ Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 778 -STVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836 S T T+ + T + TA + S + T TST + Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229 Query: 837 TSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYND 896 S ++ + GS +T+ S+ + + P AT+ T+ A T++ Sbjct: 1230 GSETNTAFII--GSETTIASTASLE-PTATSLTGSETTTVSITASGATAASTTVSSTTFV 1286 Query: 897 LSKNT 901 L+K T Sbjct: 1287 LTKAT 1291 >gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] Length = 680 Score = 60.8 bits (146), Expect = 7e-09 Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 7/90 (7%) Query: 43 PSPPHSSNGHSPQDTSTSPIKKKKKP----GLLNSNNKEQDGRNDFYCWVCHREGQVLCC 98 P+ P SS+ SP++ T P L + + + D DF C VC + GQ+L C Sbjct: 445 PTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSPTSTDGDIHEDF-CSVCRKSGQLLMC 503 Query: 99 ELCPRVYHAKCL--RLTSEPEGDWFCPECE 126 + C RVYH CL L + P+G W CP C+ Sbjct: 504 DTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 533 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 60.1 bits (144), Expect = 1e-08 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%) Query: 717 SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 776 +G E E E + +T +T GS + T T S T+ + A + +T Sbjct: 549 TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605 Query: 777 SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 836 +ST + + TGS TA +ST + T S + S T+V Sbjct: 606 ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656 Query: 837 TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 895 ++T S +TS+ GS +T VS+ ++ ++T + + + G+ T + Sbjct: 657 STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716 Query: 896 DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 955 T ++I E + + T +E + + +A Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776 Query: 956 VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1015 + E + K A+ K +F T+ + S S Sbjct: 777 IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831 Query: 1016 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1075 T P A +E T T + S+ +++ST+ + + TAS + T+A +T GS Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891 Query: 1076 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1121 T +S ++ S + +S S+ ST T+ ST+ Sbjct: 892 ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 55.1 bits (131), Expect = 4e-07 Identities = 136/736 (18%), Positives = 264/736 (35%), Gaps = 49/736 (6%) Query: 415 TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 469 TG + + S M+T S+ TG++ D+ E T++ +A E+ + +TA Sbjct: 549 TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 470 SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 527 S A ++T A S +GS + S+ TT + + S T ++ + + + E + Sbjct: 607 STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 528 SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 587 + + ++T V + + + +I + SE T+ E S+ + Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725 Query: 588 EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 647 + S + ++ + + E +E E + T I T+ Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783 Query: 648 PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 707 AS AS + F+E ++ + + +++ TV + SE+ Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833 Query: 708 LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 761 G + + G E E E + +T +TT+GS + T T Sbjct: 834 PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890 Query: 762 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 820 S T+ + + T+T+ST + TGS + T + + + ST Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950 Query: 821 QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 879 + IT S S T VT+ S S+ GS +T VS+ ++ A+ ++ Sbjct: 951 SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010 Query: 880 SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 938 S+ + GT T I + TT T A + + + T Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070 Query: 939 AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 998 +E + + + A ET ++ T+ Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119 Query: 999 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1054 +A S T +A+ E T ET S+ GS ++T SA T ++++ Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179 Query: 1055 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1114 ET+ + S +T + ET ++ GS + + ++++ + + ST S Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239 Query: 1115 NTSTSTKSLLPKESRL 1130 + T+T ++ E+ + Sbjct: 1240 GSETNTAFIIGSETTI 1255 Score = 50.1 bits (118), Expect = 1e-05 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%) Query: 740 KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 799 +T ++T GS + +P ++++ + + TTST+ + T + + + Sbjct: 34 ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93 Query: 800 LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 859 TA + V S T + + + + T T T++ + + +++GS +T VS+V Sbjct: 94 ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151 Query: 860 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919 ++ A +AD A T MT ++ S+ T ST E + Sbjct: 152 SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197 Query: 920 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979 + + E T A S + +E K + V + A+ Sbjct: 198 STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257 Query: 980 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039 + NT++ E K+ T S T + A + +E S+ GS Sbjct: 258 TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302 Query: 1040 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1086 + ST S+ T A+ + A +T+ +GS T +SI +GS Sbjct: 303 TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361 Query: 1087 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128 +D + ++++ +S++ +T S + +T S E+ Sbjct: 362 ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403 Score = 48.5 bits (114), Expect = 4e-05 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%) Query: 375 DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 432 D N +A TA + + T + S G +S +D + +ST Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659 Query: 433 SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 490 S T + E + AT S + S E S +TK GS + + Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719 Query: 491 PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 542 +++ T ++ T+ TT S + + + ++T ++ Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779 Query: 543 PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 602 + + S + + T S + +E+ T + + + ++ ++ SE I Sbjct: 780 SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837 Query: 603 QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 662 S E T EG + ++ + T E E +T+ SE A Sbjct: 838 AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886 Query: 663 SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 720 S E + + + G + T + T SE V G + + E Sbjct: 887 STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929 Query: 721 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 777 G + E S V + TV + T V T S T+A+ A T T ST+ Sbjct: 930 GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989 Query: 778 STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 830 + T TA ++TGS + T + + + T E T +T Sbjct: 990 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049 Query: 831 STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 890 + T TST+ S T S + S ++ ADL T S + T+ Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103 Query: 891 TEIYNDLSKNTTGST 905 T +Y SK TT ST Sbjct: 1104 TTVYITGSKTTTAST 1118 Score = 47.4 bits (111), Expect = 8e-05 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%) Query: 409 PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 468 P +G +S + + +ST S T + A + T++ SE + K + Sbjct: 187 PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238 Query: 469 ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 528 + + T AGS + + + + T D +TT S + ++ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296 Query: 529 ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 588 ++ ++T I P+ S + + + + + + T V + SE + Sbjct: 297 STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355 Query: 589 KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 645 S SE +D S+ TE E E S V T V I + ++ Sbjct: 356 ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413 Query: 646 TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 703 T+ +E ++ AV + + SE S + + +++ TV + Sbjct: 414 TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470 Query: 704 SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 751 SE++ G + ++G E G E S V TTV + Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530 Query: 752 PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 807 T V T S T+ + T+T+ST +T + A T + + TA Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590 Query: 808 AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 859 + V + ++ E T + +T + T ST SS T+S GS +T VS+ + Sbjct: 591 SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650 Query: 860 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 919 ++ + + + + S+ T++ ++ + +T GS + E K+ Sbjct: 651 SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705 Query: 920 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 979 + + E+T A + S + A + ET + Sbjct: 706 STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760 Query: 980 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1039 ++ T S T+ + + + +ET S+ GS Sbjct: 761 -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791 Query: 1040 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1096 + ST S+ T + T A + +T+ +GS P+S + + + Sbjct: 792 TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851 Query: 1097 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1128 +++ +S++ +T S ++ T+T + + E+ Sbjct: 852 ETTTASTEGSETTTASTESSETTTATTIGSET 883 Score = 45.8 bits (107), Expect = 2e-04 Identities = 135/719 (18%), Positives = 240/719 (33%), Gaps = 51/719 (7%) Query: 412 SGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASP 471 +G +S +D + ST S T + A+++ + S + + +T S Sbjct: 589 AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648 Query: 472 ASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESV 531 ++T S +GS + + + TT S TGS ++ + S SE+ Sbjct: 649 TDSETTMV-STTGSERTITSTEGSETTT----VSATGSETTVSTEGSGTTTVSITGSETT 703 Query: 532 QQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSD 591 + +T S + +I + E SE + E S++ + + Sbjct: 704 KVSTTG----SETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTG 759 Query: 592 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPV--EIKEELKSTSPA 649 S + + + + +E + E + V V E E +++ A Sbjct: 760 SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819 Query: 650 SEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELV 709 SE + P SE + + E T S++ + Sbjct: 820 SETTTVSTAGSETIPASTAG-SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878 Query: 710 IDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAG 769 I + EG + E S + TTV + T T S T+A+ Sbjct: 879 IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938 Query: 770 -----ATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEI 824 T +T+ S T+TV+A T TA ST + Sbjct: 939 EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT----TASTAGSETTTVSTAGSETT 994 Query: 825 TQSPSTSTITLVTSTQS-SPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMM 883 T S S T V+ST S + V+++G+ +T+ S+ ++ T + A YT+ Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSE 1052 Query: 884 DAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQ 943 T TE + +TTGS +E + + E T + Sbjct: 1053 TTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITG 1110 Query: 944 SLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAH 1003 S E + V T + A+ + S Sbjct: 1111 S---------KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS---------- 1151 Query: 1004 WPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKS 1063 E T + A A T T + S+ +++ST + + TAS + + T+A + Sbjct: 1152 --ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209 Query: 1064 KESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS---SSDEKRGSTRSDHNTSTS 1119 +T SGS ET ++ GS + S ++++ + S+ ST S T+TS Sbjct: 1210 GSETTTASTSGS-ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1267 Score = 44.7 bits (104), Expect = 5e-04 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%) Query: 735 QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 794 + V TT S + ET +++ ++T+ +TTS+ +TVT TA + T S V Sbjct: 94 ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150 Query: 795 KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 851 + ET A S+T + + + TIT T+ + V+++GS Sbjct: 151 GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203 Query: 852 STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 907 +T VS+ ++ A+ + A+ + T+K+ A G+ T + S+ T ST + Sbjct: 204 TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261 Query: 908 EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 967 E E K + E T A S + + + + + Sbjct: 262 ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310 Query: 968 VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1025 + TK A+ + +F T + S T +A+ + D+ Sbjct: 311 PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368 Query: 1026 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1080 +ET S++GS ++ST+ + + T S + + T+ + +T GS T + Sbjct: 369 TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428 Query: 1081 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1120 ++ + ++ S +S S S+ ST T+ +T Sbjct: 429 TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468 Score = 35.8 bits (81), Expect = 0.24 Identities = 91/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%) Query: 407 SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 466 S+ + TG + + S + S + + + + + T ++S+ + F + Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809 Query: 467 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 525 S + AST + ++S + P +A T T TST GS + + S+ Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868 Query: 526 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 585 E SE+ +T + S + + E + E SE T V + SE Sbjct: 869 ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922 Query: 586 DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 641 + S + SE + + S+ T E + E S + T Sbjct: 923 TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981 Query: 642 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 701 E + S A + +++ + SE S + + + +++ TV Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038 Query: 702 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 759 + SE+ V G + + ++ + + T +TTV + T T Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Query: 760 RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 819 S T+ + T+T+ST A + T S + T V V ++TV Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156 Query: 820 QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 868 E T S + + TST+ S T+S GS +T S+ ++ A+ + Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209 Score = 34.7 bits (78), Expect = 0.53 Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 5/153 (3%) Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803 +TT + T T S T+A+ A + T+T+ST + +GS + Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE 1232 Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTSSGSMSTLVSSVNA 860 + P+ N++ + E T + + S T T +T ++++ + ++ + ++V++ Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292 Query: 861 DLPIATASADVAADIAKYTSKMMDAIKGTMTEI 893 + T + DV+ I T+ M + T T + Sbjct: 1293 TTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1323 Score = 32.7 bits (73), Expect = 2.0 Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 23/166 (13%) Query: 744 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 803 +TTV + S T T S T+ + T+T ST+ A +A GS Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA--------- 1173 Query: 804 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNAD 861 +++ + E T + + + T ST S T+S GS +T S+ ++ Sbjct: 1174 -----------TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222 Query: 862 LPIATASADVAADIAKYTSKMMDA-IKGTMTEIYNDLSKNTTGSTI 906 A + + + S+ A I G+ T I + S T +++ Sbjct: 1223 TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.123 0.353 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,938,830 Number of Sequences: 37866 Number of extensions: 2348693 Number of successful extensions: 25052 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 396 Number of HSP's successfully gapped in prelim test: 1190 Number of HSP's that attempted gapping in prelim test: 13648 Number of HSP's gapped (non-prelim): 8526 length of query: 1135 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1022 effective length of database: 13,968,660 effective search space: 14275970520 effective search space used: 14275970520 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.