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Search of human proteins with 34335262
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
(1188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ... 2404 0.0
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ... 2322 0.0
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 2255 0.0
gi|238814389 zinc finger, MYND domain containing 11 isoform a [H... 186 1e-46
gi|238814385 zinc finger, MYND domain containing 11 isoform a [H... 186 1e-46
gi|238814387 zinc finger, MYND domain containing 11 isoform b [H... 182 2e-45
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 89 2e-17
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 89 2e-17
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 86 2e-16
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 77 1e-13
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 72 3e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 7e-12
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 70 9e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 69 3e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 69 3e-11
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 68 5e-11
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 68 5e-11
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 67 1e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 65 3e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 65 3e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ... 65 4e-10
gi|38788274 bromodomain PHD finger transcription factor isoform ... 65 4e-10
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 62 2e-09
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 60 2e-08
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 59 2e-08
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 59 2e-08
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 59 2e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 59 4e-08
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 58 6e-08
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 56 2e-07
>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
sapiens]
Length = 1188
Score = 2404 bits (6229), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
Query: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV
Sbjct: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
Query: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
Query: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
Query: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
Query: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
Query: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
Query: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
Query: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
Query: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
Query: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
Query: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
Query: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
Query: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
Query: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
Query: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140
KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140
Query: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188
AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188
>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
Length = 1160
Score = 2322 bits (6018), Expect = 0.0
Identities = 1159/1188 (97%), Positives = 1159/1188 (97%), Gaps = 28/1188 (2%)
Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
Query: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV
Sbjct: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
Query: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
Query: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
Query: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
Query: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
Query: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
Query: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
Query: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
Query: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
Query: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
Query: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
Query: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
Query: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
Query: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
Query: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140
KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS------------------------- 1115
Query: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188
HSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1116 ---DHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1160
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 2255 bits (5844), Expect = 0.0
Identities = 1134/1188 (95%), Positives = 1134/1188 (95%), Gaps = 53/1188 (4%)
Query: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
Query: 61 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
PIKKKKKPGLLNSNNKEQ DGRNDFYCWVCHREGQV
Sbjct: 61 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95
Query: 121 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 96 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155
Query: 181 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 156 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215
Query: 241 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 216 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275
Query: 301 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 276 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335
Query: 361 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 336 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395
Query: 421 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 396 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455
Query: 481 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 456 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515
Query: 541 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 516 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575
Query: 601 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 576 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635
Query: 661 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 636 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695
Query: 721 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 696 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755
Query: 781 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 756 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 816 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875
Query: 901 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 876 AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935
Query: 961 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 936 LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995
Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 996 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055
Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140
KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS
Sbjct: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS------------------------- 1090
Query: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188
HSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1091 ---DHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1135
>gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo
sapiens]
Length = 602
Score = 186 bits (472), Expect = 1e-46
Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%)
Query: 97 PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
P D + + N D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP
Sbjct: 88 PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144
Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
C I + +++ L+F + +MK+ D +K +HP Y +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192
Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
+D+ T+++ + Y E F ADA+ +LHN +I+ G + + IA+++ K HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252
Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
+E+++C C+ + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312
Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
H RAW+P N ++ I K + A E+E++ +R
Sbjct: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358
Score = 95.9 bits (237), Expect = 2e-19
Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
+ +V+ K+ P T ++ + P S+ST ++A P + +
Sbjct: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460
Query: 901 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
S D T+I+ND K T + E + +LR E+E+ + +Q +
Sbjct: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513
Query: 953 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011
++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++
Sbjct: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572
Query: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036
+CCWNTSYC CQQ HW EH ++C
Sbjct: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598
>gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo
sapiens]
Length = 602
Score = 186 bits (472), Expect = 1e-46
Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%)
Query: 97 PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
P D + + N D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP
Sbjct: 88 PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144
Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
C I + +++ L+F + +MK+ D +K +HP Y +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192
Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
+D+ T+++ + Y E F ADA+ +LHN +I+ G + + IA+++ K HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252
Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
+E+++C C+ + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312
Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
H RAW+P N ++ I K + A E+E++ +R
Sbjct: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358
Score = 95.9 bits (237), Expect = 2e-19
Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
+ +V+ K+ P T ++ + P S+ST ++A P + +
Sbjct: 401 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460
Query: 901 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
S D T+I+ND K T + E + +LR E+E+ + +Q +
Sbjct: 461 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513
Query: 953 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011
++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQWC NC++EA++
Sbjct: 514 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572
Query: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036
+CCWNTSYC CQQ HW EH ++C
Sbjct: 573 HCCWNTSYCSIKCQQEHWHAEHKRTC 598
>gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo
sapiens]
Length = 567
Score = 182 bits (462), Expect = 2e-45
Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 24/286 (8%)
Query: 97 PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
P D + + N D+YC+ CH G+VL C+LC RVYH+KCL R +S P W CP
Sbjct: 88 PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144
Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
C I + +++ L+F + +MK+ D +K +HP Y +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192
Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
+D+ T+++ + Y E F ADA+ +LHN +I+ G + + IA+++ K HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGDSEQ-ADIARMLYKDTCHEL 251
Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
+E+++C C+ + + DNWFC PC H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 252 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 311
Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
H RAW+P N ++ I K + A E+E++ +R
Sbjct: 312 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 357
Score = 40.0 bits (92), Expect = 0.013
Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 17/170 (10%)
Query: 841 SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
+ +V+ K+ P T ++ + P S+ST ++A P + +
Sbjct: 400 NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 459
Query: 901 AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
S D T+I+ND K T + E + +LR E+E+ + +Q +
Sbjct: 460 GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 512
Query: 953 SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQW 1001
++ N++ M + +Q E+ ++ + E+KK L + +Q + +TKKKQW
Sbjct: 513 NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQW 561
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)
Query: 47 HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
+SS + ++T S +P +PGL N+ P K PL + +
Sbjct: 766 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 821
Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
D N+ +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E
Sbjct: 822 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 881
Query: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
+ S E L L +K ++ + AFQ PVPL PDY + I
Sbjct: 882 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 940
Query: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
+PMDL T++K ++ MY E F+AD + I NC +N + +++A IK+
Sbjct: 941 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 993
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 89.0 bits (219), Expect = 2e-17
Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)
Query: 47 HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
+SS + ++T S +P +PGL N+ P K PL + +
Sbjct: 732 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 787
Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
D N+ +C VC G++LCCE CP+V+H C LT+ P G+W C C ++ E
Sbjct: 788 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 847
Query: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
+ S E L L +K ++ + AFQ PVPL PDY + I
Sbjct: 848 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 906
Query: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
+PMDL T++K ++ MY E F+AD + I NC +N + +++A IK+
Sbjct: 907 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 85.9 bits (211), Expect = 2e-16
Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 14/182 (7%)
Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKITVAEC--- 158
D N+ +C VC G +LCCE CP+V+H C L S P GDW C C I E
Sbjct: 883 DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYD 942
Query: 159 ---IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPM 213
++ K T + + + + + FQ+PVP P+Y + I PM
Sbjct: 943 CDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYYKIIKKPM 1001
Query: 214 DLCTLEKNAKKKM---YGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMN 270
DL T++K +KK Y + F+AD + I NC +N + ++ Q K V E ++
Sbjct: 1002 DLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLT 1061
Query: 271 EI 272
EI
Sbjct: 1062 EI 1063
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 77.0 bits (188), Expect = 1e-13
Identities = 51/158 (32%), Positives = 73/158 (46%), Gaps = 14/158 (8%)
Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKITVAEC--- 158
D N+ +C VC G +LCCE CP+V+H C L S P GDW C C I E
Sbjct: 883 DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYD 942
Query: 159 ---IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPM 213
++ K T + + + + + FQ+PVP P+Y + I PM
Sbjct: 943 CDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYYKIIKKPM 1001
Query: 214 DLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYN 248
DL T++K +KK Y + F+AD + I NC +N
Sbjct: 1002 DLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN 1039
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 72.0 bits (175), Expect = 3e-12
Identities = 119/731 (16%), Positives = 258/731 (35%), Gaps = 19/731 (2%)
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
SD S S +S + + D+ + SS S S +S D D S +S + + + ++ S
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLI 566
S S + + +D + ++ S + N S D + S S ++
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 567 SPKRQIRSRFQLNLDKT-IESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 625
S S + D + +S + N S D ++ S+ S SDSSDS S+
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 626 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 685
S + D S+ +N + +S +S+ ++ D
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 686 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 745
+ + + D D +DS G DSDS + D S
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 746 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 805
N + + S + + S + S + S + S+ + ++ S++S+
Sbjct: 872 DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 806 TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 865
+ + + +++ +S + + + S S+ + S+
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSN-------SSDSSNSSDSSDSNSSDSSDSSNSSD 984
Query: 866 SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 925
SS SS S + SS ++D ++ S+D + + +S D+ + + +D S +
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 926 TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELT-MAEMRQSLEQERDRLIAEVKKQ 984
+ S ++ + + S+ + + + +E S + ++
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 985 LELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ 1044
+ ++ +N + ++S ++ + S S ++
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSS------DSSDSSDSSDSSNSSDSSDSSESSDSSDS 1156
Query: 1045 QEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETP 1104
++ ++ + SS S SS S S+++ +S ++S S +S + D S S ++
Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSS 1214
Query: 1105 SSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGSTR 1164
S + S + + + ++D N S S+ S+ S+DE ++
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Query: 1165 SDHNTSTSTKS 1175
S + + + S
Sbjct: 1275 SGNGNNNGSDS 1285
Score = 63.5 bits (153), Expect = 1e-09
Identities = 95/568 (16%), Positives = 202/568 (35%), Gaps = 37/568 (6%)
Query: 607 SDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKE 666
SDS DS+ SDSS+S SD ++ + D + D S+ +N + +
Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606
Query: 667 ELKSTSPASEKADPGAVKDKASPEPE-KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGL 725
S+ + + D + E + D K+ S D D +DS
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 726 DSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTR 785
DS S+ D S N + + S + + S + S S +
Sbjct: 667 DSSDSSD-----SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 786 SSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQ 845
+S+ + ++ ++ ++ +S++ + + ++ S ++S+
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--------------SNSSDS 767
Query: 846 QKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
S S+ + S SS SS S ++ SS ++D ++ S+D + + +S
Sbjct: 768 SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827
Query: 906 KMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAE 965
D+ + + +D S ++ GS R + + S+ ++ + ++
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR----SDSSNSSDSSDSSDSSNSSD--SSD 881
Query: 966 MRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQ 1025
S E ++ + + + + + + N++ D
Sbjct: 882 SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD---- 937
Query: 1026 QAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSA 1085
S + ++ +D+ ++++ N S S+S+ S+ S +S S + S+
Sbjct: 938 -----SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 1086 EKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYH 1145
+ S S S+ S + SS SN S D + + + + +
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 1146 SRSNKSSWSSSDEKRGSTRSDHNTSTST 1173
S + +S SSD S SD + S+ +
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Score = 61.2 bits (147), Expect = 6e-09
Identities = 74/335 (22%), Positives = 124/335 (37%), Gaps = 17/335 (5%)
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
S+ S S+NSS + S D+ + SS+ S S +S D D S +S +S + + S
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLI 566
S S+ + +D + ++ S + N S D + S+S +
Sbjct: 1031 SDSSD-------SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 567 SPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS-EKSDSSDSEYISD 625
S S + D + S + + S D + SDS DS + SDSSDS SD
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 626 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 685
S E D+ D D S+ ++ + +S +S+ +D D
Sbjct: 1144 SSDSS--ESSDSSDSSD-SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Query: 686 KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 745
+ D S+ + S D D +DS + DS S+S D +
Sbjct: 1201 SSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSNESSDS-SDSSDSSDSSNSSDSSD 1254
Query: 746 GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
+ + + + D K+ GS S ++
Sbjct: 1255 SSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289
Score = 51.6 bits (122), Expect = 4e-06
Identities = 94/571 (16%), Positives = 212/571 (37%), Gaps = 24/571 (4%)
Query: 606 HSDSEDSEKSDSSDSEYISDDEQKSKNEP--EDTEDKEGCQMDKEPSAVKKKPKPTNPVE 663
++ E + + SDS+ DD+ S ++ D+ D + K K +
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS 552
Query: 664 IKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL 723
+ ++S +S+ +D + +S + + S+ + S D D +DS
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 724 GLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVL 783
DS S+ D + S +K + + S D + S + S + ++
Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD-SNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 784 TRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST 843
+ SS +S++ ++ ++ +S + + + ++ S +++ NS++
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS--------NSNS 723
Query: 844 VQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKY 903
S S+ + S+ SS SS S + SS ++D ++ S+D +
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD-----SSD 778
Query: 904 TSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
+S D+ + + +D S N++ S+ + + + + S + + +
Sbjct: 779 SSNSSDSNDSSNSSDSSD-SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 964 AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
+ D ++ + + ++ ++ + N+S
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADA-EVNTETLNKSSQGSSSSTQSAPSETASASKEKE 1082
+ S + ++ +D+ E + + N +S SS+S+ S+ S +S S +
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 1083 TSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQ 1142
S++ S S D S S + SS SN S D + + + + + +
Sbjct: 958 NSSDSSNSS----DSSDSNSSDSSD--SSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 1143 KYHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1173
S ++ S +SSD S SD + S+ +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Score = 42.0 bits (97), Expect = 0.003
Identities = 45/206 (21%), Positives = 79/206 (38%), Gaps = 2/206 (0%)
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
SD S S++SS + S D+ + SS S S +S D D S +S +S + + S
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 507 LSGSPKPFSPQLS--APITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVP 564
S S S + + +D ++++ S + + S D + S+S +
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 565 LISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYIS 624
S S + D S + + S + + + SDS DS + +S+ S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 625 DDEQKSKNEPEDTEDKEGCQMDKEPS 650
+ N + D EG + S
Sbjct: 1274 KSGNGNNNGSDSDSDSEGSDSNHSTS 1299
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 70.9 bits (172), Expect = 7e-12
Identities = 117/564 (20%), Positives = 218/564 (38%), Gaps = 64/564 (11%)
Query: 563 VPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEY 622
+P +S +++S ++ + + E K + + E +E+ E ++ E+ E + E
Sbjct: 429 IPSVSTHIKVKSEEKIKVVEKSE--KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 623 ISDDEQKSKNEPEDTED---KEGCQMDKE-----------PSAVK--KKPKPTNPVEIKE 666
+E++++ E+T+ +E +KE P+ K +K + +P E+K
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546
Query: 667 ELKSTSPASEKADPGAVKDKASPE---PEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL 723
K+ SPA E+A K+ PE PEK+ ++ P K K K+E SP
Sbjct: 547 PEKAKSPAKEEA-------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA--- 596
Query: 724 GLDSDSESELVIDLGEDHSGREGRKN--KKEPKEPSP-KQDVVGKTPPSTTVGSHSPPET 780
++ S + + E+ K+ K+E K P+ K K+P S ++
Sbjct: 597 --EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 781 PVLTRSSAQTSA-----AGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ 835
P + + A A A + S V A +P SPVK++ K +P +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 836 RVVWNSSTVQQ-KEITQSPSTSTITLVTSTQSSPLVTSSGSMSTL-VSSVNADLPIATAS 893
KE ++P + + +S S TL V S A P A
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP---AK 771
Query: 894 ADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRL-RIEIEKLQWLHQQEL 952
+ + K+ K +K + S S + E + EI K + +
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVK------SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 953 SEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFY 1012
E K E+ + E + E+E+ + +++ + +K++A + K K+ A+
Sbjct: 826 EEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE- 883
Query: 1013 CCWNTSYCDYPCQQAHWPEHMKSCTQSATAP-----QQEADAEVNTETLNKSSQGSSSST 1067
++ + K T AP +++A + TE K + +
Sbjct: 884 ---KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 1068 QSAPSETASASKE-KETSAEKSKE 1090
S P+E A+ E K+T EK+K+
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKK 964
Score = 48.5 bits (114), Expect = 4e-05
Identities = 70/399 (17%), Positives = 147/399 (36%), Gaps = 39/399 (9%)
Query: 401 PTNPSAGT-AKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSS 459
P PS T K+ +EK+K+ + + +++ + ++ + +
Sbjct: 427 PKIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485
Query: 460 VHTGSDVEQDAEKKATSSH-----FSASEESMDFLDKSTASPASTKT---------GQAG 505
G + E + ++ T S S +E+ + + SPA K+ +
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545
Query: 506 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 565
S + P + +P K+ + S + KA+ KE ++S + +P
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 566 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 625
SP ++ E K+ + S + + +++ EK+ S + E
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVK--SPEKAKSPTKEEAKSPEKAKSPEKE---- 658
Query: 626 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVE--IKEELKSTSPASEKADPGAV 683
E KS + + E +K S VK + K + +KEE KS A A
Sbjct: 659 -EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717
Query: 684 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 743
+ + P K+ ++ + + P+K++ K ++ SP E +D+ +
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP----------EKAKTLDVKSPEAK 767
Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPV 782
++ + P + P++ K+P V S ++P+
Sbjct: 768 TPAKEEARSPADKFPEK---AKSPVKEEVKSPEKAKSPL 803
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/324 (19%), Positives = 123/324 (37%), Gaps = 17/324 (5%)
Query: 451 RSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGS 510
+SP S S +++A+ A + + E++ + + SPA K+
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAK---SPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629
Query: 511 PKPFSPQLSAPITTKTDKTSTTGSILNLNLDRS--KAEMDLKELSESVQQQSTPVPLISP 568
+ SP+ + T + K+ +S KA+ +K ++S ++ +PV +
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Query: 569 KRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ 628
+ K+ E K+ + S + + +++ EK+ S E E+
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749
Query: 629 KSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKAS 688
E T D + + + P P + K +K + EKA +D +
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809
Query: 689 PE---PEKD-----FSEKAKPSPHPIKDKLKGKDETDSP-TVHLGLDSDSESELVIDLGE 739
PE P+K+ E+ KP +K+ K +E +P T DS+ E + +
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE---EAPK 866
Query: 740 DHSGREGRKNKKEPKEPSPKQDVV 763
+ + + KKEP PK+ V
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKV 890
Score = 38.1 bits (87), Expect = 0.050
Identities = 70/322 (21%), Positives = 123/322 (38%), Gaps = 25/322 (7%)
Query: 451 RSPMSTNSSVH----TGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
+SP S V T + +++A S + S E LD SP + + +
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD--VKSPEAKTPAKEEA 774
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSES-VQQQSTP--V 563
S + K F + +P+ + S L + + E+ KE +S V+++ P V
Sbjct: 775 RSPADK-FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833
Query: 564 PLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYI 623
+ P ++ KT E ++ E VE EK S E
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 624 SDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAV 683
++ + K P ++ KE + K+K E+ ++ + A E + P A
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK------TEVAKKEPDDAKAKEPSKP-AE 946
Query: 684 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 743
K +A+PE + EKAK K K + K + D T+ S S+ + E S
Sbjct: 947 KKEAAPEKKDTKEEKAKKPEE--KPKTEAKAKEDDKTL-----SKEPSKPKAEKAEKSSS 999
Query: 744 REGRKNKKEPKEPSPKQDVVGK 765
+ +K+ K P++ + + GK
Sbjct: 1000 TD-QKDSKPPEKATEDKAAKGK 1020
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 70.5 bits (171), Expect = 9e-12
Identities = 61/225 (27%), Positives = 96/225 (42%), Gaps = 32/225 (14%)
Query: 102 PQDGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAE-- 157
P N+ +C VC G++LCC+ CP+V+H C L S P G+W C C +T E
Sbjct: 964 PAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEME 1023
Query: 158 ------CIE----TQSKAMTMLTIEQLSYL-LKFAIQKMKQPGTDAFQKPV-PLEQHPDY 205
C S ++M ++ L L + P F +PV PL +H Y
Sbjct: 1024 YDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLP----FHEPVSPLARH--Y 1077
Query: 206 AEYIFHPMDLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVI 262
+ I PMDL + + +KK Y E ++D + + NC +N + ++ + + +
Sbjct: 1078 YQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLE 1137
Query: 263 KICEHEMNEIEVCPECYLAACQKRDNWFCE-----PCSNPHPLVW 302
E + EI PE A ++ D+ E CS P W
Sbjct: 1138 VFFEGWLKEI--YPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPW 1180
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 68.9 bits (167), Expect = 3e-11
Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)
Query: 386 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 445
R+P PN + T + +I ++ V N + ++S S S T R+I
Sbjct: 94 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 142
Query: 446 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 503
S + + + + +KK T E +D D +P T T Q
Sbjct: 143 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 201
Query: 504 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 558
+S SPK P +P+ S P + T K ++ ++ + K+ S ++
Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261
Query: 559 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 618
++T + ++ K + + + T E + + E + ++
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321
Query: 619 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 673
E + + EP T K KEP+ K+P PT P E K +P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381
Query: 674 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 733
+ K+ P K+ A P+K P+P K+ + +PT ++
Sbjct: 382 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434
Query: 734 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 790
E + PKEP+P K P TT SP P+ P T SA T
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 791 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 836
+ TT+ S+ T P+P T P P PKE AP +
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 533
Score = 59.7 bits (143), Expect = 2e-08
Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)
Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
K T P +G +G K +P S TT+ +K ST+ I
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 211
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
+ + P P + P L ++K T+E+ + + S D
Sbjct: 212 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 267
Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
+++ EK+ + D S K + E T KEP+ K+P T P E
Sbjct: 268 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 327
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
++P + K +P K++P K+ P+P K+ + +PT
Sbjct: 328 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 375
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
KEP+P T P + P +
Sbjct: 376 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
A T+ T TT T PAP P KK P PKE AP + ++
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469
Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
T + SP+T T+T+S+P T + +T S+
Sbjct: 470 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Score = 53.9 bits (128), Expect = 9e-07
Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)
Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
EP T KE + +A K+P PT P K K +P + K DK +P
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 780
Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
K+ + P P K ++P T + + ++ I D S E
Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840
Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
+ + E SPK+ V T +TP T+ T+A T +T
Sbjct: 841 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 888
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
T AP T KETA ++ + T ++T + + T IT +
Sbjct: 889 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 936
Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
+T +P VT++ T +N P TA A +K T+
Sbjct: 937 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 977
Score = 52.4 bits (124), Expect = 3e-06
Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)
Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
+T PA T T A + P P + + AP T K + TT + A KE
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 550
Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
+ + ++ P +PK + + +T + +L + T E
Sbjct: 551 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603
Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
E+ + E + + EP T K KEP+ K+P PT P E
Sbjct: 604 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
K T+P + K P +K+ A P+K ++ P+ K+ + +PT G
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 718
Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
+ PKEP+P K P TT +P ++
Sbjct: 719 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 752
Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
+ A A T+T + T+ PA T K+ P PKE AP +
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 805
Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
T P+TS ++ T+T+ + S ST S P A + + T+K
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 862
Query: 908 MDAIKGTMTEIYND 921
A K MT D
Sbjct: 863 PAATKPEMTTTAKD 876
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)
Query: 471 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 530
++ ++SS S+S ++ + S S A+ + + + + K + + P D+
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 182
Query: 531 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 590
+ LD ++ + S + + + P I+ + I R L +
Sbjct: 183 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 226
Query: 591 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 649
++ S++ V + +++++ +++ + +D ++K+ + E ++ D P
Sbjct: 227 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283
Query: 650 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 706
S V KP P K E + PA ++ P K+ AS P++ P+P I
Sbjct: 284 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 330
Query: 707 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 766
K +PT PKEP+P T
Sbjct: 331 KS---------APTT-------------------------------PKEPAPTTTKSAPT 350
Query: 767 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 826
P + + P + A T+ TT+ S+ T PAP KK P
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 406
Query: 827 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 857
PKE AP + ++ + T+ P+ +T
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437
Score = 47.0 bits (110), Expect = 1e-04
Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)
Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
T T + Q D + + EK D+ + K+L +KP T +
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 302
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
P+ P T + ++ S+ + E + +T S +T A +
Sbjct: 303 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 358
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
+ P P +P+ AP TTK +TT S + + A KE + + ++
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418
Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
TP P + + + + E T + + E S +
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478
Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
+ + + EP T K KEPS K+P PT P E
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
+E T+P ++K P K+ A P++ K +KL E
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
+PT L + E E+ + + KEP +PK+
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
K P TT +P E T ++ A T+ T
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
T PA T K+ P PK TAP +T+++ T + L +T
Sbjct: 719 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 767
Query: 867 SPLVTSS 873
P T+S
Sbjct: 768 GPTSTTS 774
Score = 42.0 bits (97), Expect = 0.003
Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)
Query: 649 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 708
P + KK P P+ + +KST+ S K P K K E E + +E+ S + ++
Sbjct: 72 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 124
Query: 709 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 768
+ S + + S S +L + ++ +KN+ + K+P+PK VV +
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 183
Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
G T TST+ V+ T P+ RP LP
Sbjct: 184 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 225
Query: 829 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 888
+ + + S TV ++ ++ T+T TST TS+ ++ + DL
Sbjct: 226 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 280
Query: 889 IATASADVAADIAKYTSKMMDAIKG 913
A + +AK T K KG
Sbjct: 281 -----APTSKVLAKPTPKAETTTKG 300
Score = 38.1 bits (87), Expect = 0.050
Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)
Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
P +P T S V T + K+ T+ H S E + + +A P + G
Sbjct: 806 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 856
Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
P +P + P T T K TT L + + A + + + + +++T + +
Sbjct: 857 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916
Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
Q+ S T L ++ V T K + +E +
Sbjct: 917 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 957
Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
N+PE+T + D+ ++ PKP P K K TS K P K K +P
Sbjct: 958 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1009
Query: 690 EPEKDFSEKAKPSP 703
P K S + +P
Sbjct: 1010 TPRKMTSTMPELNP 1023
Score = 33.9 bits (76), Expect = 0.95
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
P + E + T+NK + + T + +T++ KEK TSA KE+ S S
Sbjct: 225 PNSDTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSA---KETQSIEKTSAKDL 280
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
P+S +L + ++ K PA TT +P P P + + + + ++ +
Sbjct: 281 APTSKVL-AKPTPKAETTTKGPA---LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 1163 TRSDHNTSTSTKSLLPKE 1180
+ T+T + PKE
Sbjct: 337 PKEPAPTTTKSAPTTPKE 354
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 68.9 bits (167), Expect = 3e-11
Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)
Query: 386 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 445
R+P PN + T + +I ++ V N + ++S S S T R+I
Sbjct: 135 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 183
Query: 446 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 503
S + + + + +KK T E +D D +P T T Q
Sbjct: 184 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 242
Query: 504 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 558
+S SPK P +P+ S P + T K ++ ++ + K+ S ++
Sbjct: 243 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302
Query: 559 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 618
++T + ++ K + + + T E + + E + ++
Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362
Query: 619 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 673
E + + EP T K KEP+ K+P PT P E K +P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422
Query: 674 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 733
+ K+ P K+ A P+K P+P K+ + +PT ++
Sbjct: 423 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475
Query: 734 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 790
E + PKEP+P K P TT SP P+ P T SA T
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 791 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 836
+ TT+ S+ T P+P T P P PKE AP +
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 574
Score = 59.7 bits (143), Expect = 2e-08
Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)
Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
K T P +G +G K +P S TT+ +K ST+ I
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 252
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
+ + P P + P L ++K T+E+ + + S D
Sbjct: 253 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 308
Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
+++ EK+ + D S K + E T KEP+ K+P T P E
Sbjct: 309 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 368
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
++P + K +P K++P K+ P+P K+ + +PT
Sbjct: 369 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 416
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
KEP+P T P + P +
Sbjct: 417 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
A T+ T TT T PAP P KK P PKE AP + ++
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510
Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
T + SP+T T+T+S+P T + +T S+
Sbjct: 511 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
Score = 53.9 bits (128), Expect = 9e-07
Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)
Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
EP T KE + +A K+P PT P K K +P + K DK +P
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 821
Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
K+ + P P K ++P T + + ++ I D S E
Sbjct: 822 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881
Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
+ + E SPK+ V T +TP T+ T+A T +T
Sbjct: 882 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 929
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
T AP T KETA ++ + T ++T + + T IT +
Sbjct: 930 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 977
Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
+T +P VT++ T +N P TA A +K T+
Sbjct: 978 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 1018
Score = 52.4 bits (124), Expect = 3e-06
Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)
Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
+T PA T T A + P P + + AP T K + TT + A KE
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 591
Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
+ + ++ P +PK + + +T + +L + T E
Sbjct: 592 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644
Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
E+ + E + + EP T K KEP+ K+P PT P E
Sbjct: 645 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
K T+P + K P +K+ A P+K ++ P+ K+ + +PT G
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 759
Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
+ PKEP+P K P TT +P ++
Sbjct: 760 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 793
Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
+ A A T+T + T+ PA T K+ P PKE AP +
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 846
Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
T P+TS ++ T+T+ + S ST S P A + + T+K
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 903
Query: 908 MDAIKGTMTEIYND 921
A K MT D
Sbjct: 904 PAATKPEMTTTAKD 917
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)
Query: 471 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 530
++ ++SS S+S ++ + S S A+ + + + + K + + P D+
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 223
Query: 531 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 590
+ LD ++ + S + + + P I+ + I R L +
Sbjct: 224 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 267
Query: 591 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 649
++ S++ V + +++++ +++ + +D ++K+ + E ++ D P
Sbjct: 268 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324
Query: 650 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 706
S V KP P K E + PA ++ P K+ AS P++ P+P I
Sbjct: 325 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 371
Query: 707 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 766
K +PT PKEP+P T
Sbjct: 372 KS---------APTT-------------------------------PKEPAPTTTKSAPT 391
Query: 767 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 826
P + + P + A T+ TT+ S+ T PAP KK P
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 447
Query: 827 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 857
PKE AP + ++ + T+ P+ +T
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478
Score = 47.0 bits (110), Expect = 1e-04
Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)
Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
T T + Q D + + EK D+ + K+L +KP T +
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 343
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
P+ P T + ++ S+ + E + +T S +T A +
Sbjct: 344 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 399
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
+ P P +P+ AP TTK +TT S + + A KE + + ++
Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459
Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
TP P + + + + E T + + E S +
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519
Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
+ + + EP T K KEPS K+P PT P E
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
+E T+P ++K P K+ A P++ K +KL E
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
+PT L + E E+ + + KEP +PK+
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
K P TT +P E T ++ A T+ T
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
T PA T K+ P PK TAP +T+++ T + L +T
Sbjct: 760 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 808
Query: 867 SPLVTSS 873
P T+S
Sbjct: 809 GPTSTTS 815
Score = 42.0 bits (97), Expect = 0.003
Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)
Query: 649 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 708
P + KK P P+ + +KST+ S K P K K E E + +E+ S + ++
Sbjct: 113 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 165
Query: 709 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 768
+ S + + S S +L + ++ +KN+ + K+P+PK VV +
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 224
Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
G T TST+ V+ T P+ RP LP
Sbjct: 225 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 266
Query: 829 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 888
+ + + S TV ++ ++ T+T TST TS+ ++ + DL
Sbjct: 267 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 321
Query: 889 IATASADVAADIAKYTSKMMDAIKG 913
A + +AK T K KG
Sbjct: 322 -----APTSKVLAKPTPKAETTTKG 341
Score = 38.1 bits (87), Expect = 0.050
Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)
Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
P +P T S V T + K+ T+ H S E + + +A P + G
Sbjct: 847 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 897
Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
P +P + P T T K TT L + + A + + + + +++T + +
Sbjct: 898 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957
Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
Q+ S T L ++ V T K + +E +
Sbjct: 958 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 998
Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
N+PE+T + D+ ++ PKP P K K TS K P K K +P
Sbjct: 999 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1050
Query: 690 EPEKDFSEKAKPSP 703
P K S + +P
Sbjct: 1051 TPRKMTSTMPELNP 1064
Score = 33.9 bits (76), Expect = 0.95
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
P + E + T+NK + + T + +T++ KEK TSA KE+ S S
Sbjct: 266 PNSDTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSA---KETQSIEKTSAKDL 321
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
P+S +L + ++ K PA TT +P P P + + + + ++ +
Sbjct: 322 APTSKVL-AKPTPKAETTTKGPA---LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 1163 TRSDHNTSTSTKSLLPKE 1180
+ T+T + PKE
Sbjct: 378 PKEPAPTTTKSAPTTPKE 395
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 68.2 bits (165), Expect = 5e-11
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
Query: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N
Sbjct: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579
Query: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
+ YNG + T+ A+ ++ +C + E +
Sbjct: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 68.2 bits (165), Expect = 5e-11
Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)
Query: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K++Y E
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465
Query: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1506
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
M P + F PV + PDY + I +PMDL T+ KN K Y E+FL D IL N
Sbjct: 1541 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1600
Query: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
+ YNG + T+ A+ ++ +C + E +
Sbjct: 1601 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1629
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 67.0 bits (162), Expect = 1e-10
Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 174 LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
LS +L+ I M+ P T F PV + DY + I PMDL TL +N +K +Y E
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
Query: 233 FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
F + I+ N YNG H LTQI++ ++ +C+ ++ E E
Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504
Score = 60.8 bits (146), Expect = 7e-09
Identities = 32/89 (35%), Positives = 47/89 (52%)
Query: 185 MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
M P + F PV + PDY + I +P+DL T+ KN K Y E+FL D IL N
Sbjct: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598
Query: 245 IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
+ YNG + T+ A+ ++ IC + E +
Sbjct: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 65.5 bits (158), Expect = 3e-10
Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)
Query: 465 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 517
D +++ KK + +E+ LD + T T Q +S SPK P +P+
Sbjct: 68 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127
Query: 518 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 577
S P + T K ++ ++ + K+ S ++++T + ++
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 578 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 634
K + + + T E + + E + ++ E + + EP
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 635 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 692
T K KEP+ K+P PT P E K +P + K+ P K+ A P+
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307
Query: 693 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 752
K P+P K+ + +PT ++ E +
Sbjct: 308 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360
Query: 753 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 809
PKEP+P K P TT SP P+ P T SA T+ TT+ S+ T
Sbjct: 361 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 810 PAPAATGSPVKKQRPLLPKETAPAVQR 836
P+P T P P PKE AP +
Sbjct: 418 PSPTTTKEPA----PTTPKEPAPTTPK 440
Score = 59.7 bits (143), Expect = 2e-08
Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)
Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
K T P +G +G K +P S TT+ +K ST+ I
Sbjct: 77 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 118
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
+ + P P + P L ++K T+E+ + + S D
Sbjct: 119 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 174
Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
+++ EK+ + D S K + E T KEP+ K+P T P E
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
++P + K +P K++P K+ P+P K+ + +PT
Sbjct: 235 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 282
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
KEP+P T P + P +
Sbjct: 283 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316
Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
A T+ T TT T PAP P KK P PKE AP + ++
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376
Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
T + SP+T T+T+S+P T + +T S+
Sbjct: 377 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411
Score = 53.9 bits (128), Expect = 9e-07
Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)
Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
EP T KE + +A K+P PT P K K +P + K DK +P
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 687
Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
K+ + P P K ++P T + + ++ I D S E
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747
Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
+ + E SPK+ V T +TP T+ T+A T +T
Sbjct: 748 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
T AP T KETA ++ + T ++T + + T IT +
Sbjct: 796 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 843
Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
+T +P VT++ T +N P TA A +K T+
Sbjct: 844 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 884
Score = 52.4 bits (124), Expect = 3e-06
Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)
Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
+T PA T T A + P P + + AP T K + TT + A KE
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 457
Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
+ + ++ P +PK + + +T + +L + T E
Sbjct: 458 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510
Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
E+ + E + + EP T K KEP+ K+P PT P E
Sbjct: 511 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
K T+P + K P +K+ A P+K ++ P+ K+ + +PT G
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 625
Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
+ PKEP+P K P TT +P ++
Sbjct: 626 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 659
Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
+ A A T+T + T+ PA T K+ P PKE AP +
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 712
Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
T P+TS ++ T+T+ + S ST S P A + + T+K
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 769
Query: 908 MDAIKGTMTEIYND 921
A K MT D
Sbjct: 770 PAATKPEMTTTAKD 783
Score = 47.0 bits (110), Expect = 1e-04
Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)
Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
T T + Q D + + EK D+ + K+L +KP T +
Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 209
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
P+ P T + ++ S+ + E + +T S +T A +
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 265
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
+ P P +P+ AP TTK +TT S + + A KE + + ++
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
TP P + + + + E T + + E S +
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385
Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
+ + + EP T K KEPS K+P PT P E
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
+E T+P ++K P K+ A P++ K +KL E
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
+PT L + E E+ + + KEP +PK+
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
K P TT +P E T ++ A T+ T
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
T PA T K+ P PK TAP +T+++ T + L +T
Sbjct: 626 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 674
Query: 867 SPLVTSS 873
P T+S
Sbjct: 675 GPTSTTS 681
Score = 38.1 bits (87), Expect = 0.050
Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)
Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
P +P T S V T + K+ T+ H S E + + +A P + G
Sbjct: 713 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 763
Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
P +P + P T T K TT L + + A + + + + +++T + +
Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823
Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
Q+ S T L ++ V T K + +E +
Sbjct: 824 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 864
Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
N+PE+T + D+ ++ PKP P K K TS K P K K +P
Sbjct: 865 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 916
Query: 690 EPEKDFSEKAKPSP 703
P K S + +P
Sbjct: 917 TPRKMTSTMPELNP 930
Score = 33.9 bits (76), Expect = 0.95
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
P + E + T+NK + + T + +T++ KEK TSA KE+ S S
Sbjct: 132 PNSDTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSA---KETQSIEKTSAKDL 187
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
P+S +L + ++ K PA TT +P P P + + + + ++ +
Sbjct: 188 APTSKVL-AKPTPKAETTTKGPA---LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 243
Query: 1163 TRSDHNTSTSTKSLLPKE 1180
+ T+T + PKE
Sbjct: 244 PKEPAPTTTKSAPTTPKE 261
Score = 33.5 bits (75), Expect = 1.2
Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)
Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 803
++ +KN+ + K+P+PK VV + G T TST+
Sbjct: 67 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 108
Query: 804 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 863
V+ T P+ RP LP + + + S TV ++ ++ T+T TS
Sbjct: 109 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 163
Query: 864 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 913
T TS+ ++ + DL A + +AK T K KG
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 207
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 65.5 bits (158), Expect = 3e-10
Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)
Query: 465 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 517
D +++ KK + +E+ LD + T T Q +S SPK P +P+
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168
Query: 518 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 577
S P + T K ++ ++ + K+ S ++++T + ++
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 578 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 634
K + + + T E + + E + ++ E + + EP
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 635 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 692
T K KEP+ K+P PT P E K +P + K+ P K+ A P+
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348
Query: 693 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 752
K P+P K+ + +PT ++ E +
Sbjct: 349 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401
Query: 753 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 809
PKEP+P K P TT SP P+ P T SA T+ TT+ S+ T
Sbjct: 402 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 810 PAPAATGSPVKKQRPLLPKETAPAVQR 836
P+P T P P PKE AP +
Sbjct: 459 PSPTTTKEPA----PTTPKEPAPTTPK 481
Score = 59.7 bits (143), Expect = 2e-08
Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)
Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
K T P +G +G K +P S TT+ +K ST+ I
Sbjct: 118 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 159
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
+ + P P + P L ++K T+E+ + + S D
Sbjct: 160 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 215
Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
+++ EK+ + D S K + E T KEP+ K+P T P E
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
++P + K +P K++P K+ P+P K+ + +PT
Sbjct: 276 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 323
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
KEP+P T P + P +
Sbjct: 324 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357
Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
A T+ T TT T PAP P KK P PKE AP + ++
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417
Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
T + SP+T T+T+S+P T + +T S+
Sbjct: 418 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452
Score = 53.9 bits (128), Expect = 9e-07
Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)
Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
EP T KE + +A K+P PT P K K +P + K DK +P
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 728
Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
K+ + P P K ++P T + + ++ I D S E
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788
Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
+ + E SPK+ V T +TP T+ T+A T +T
Sbjct: 789 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
T AP T KETA ++ + T ++T + + T IT +
Sbjct: 837 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 884
Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
+T +P VT++ T +N P TA A +K T+
Sbjct: 885 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 925
Score = 52.4 bits (124), Expect = 3e-06
Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)
Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
+T PA T T A + P P + + AP T K + TT + A KE
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 498
Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
+ + ++ P +PK + + +T + +L + T E
Sbjct: 499 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551
Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
E+ + E + + EP T K KEP+ K+P PT P E
Sbjct: 552 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
K T+P + K P +K+ A P+K ++ P+ K+ + +PT G
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 666
Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
+ PKEP+P K P TT +P ++
Sbjct: 667 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 700
Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
+ A A T+T + T+ PA T K+ P PKE AP +
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 753
Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
T P+TS ++ T+T+ + S ST S P A + + T+K
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 810
Query: 908 MDAIKGTMTEIYND 921
A K MT D
Sbjct: 811 PAATKPEMTTTAKD 824
Score = 47.0 bits (110), Expect = 1e-04
Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)
Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
T T + Q D + + EK D+ + K+L +KP T +
Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 250
Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
P+ P T + ++ S+ + E + +T S +T A +
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 306
Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
+ P P +P+ AP TTK +TT S + + A KE + + ++
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
TP P + + + + E T + + E S +
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426
Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
+ + + EP T K KEPS K+P PT P E
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
+E T+P ++K P K+ A P++ K +KL E
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
+PT L + E E+ + + KEP +PK+
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
K P TT +P E T ++ A T+ T
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
T PA T K+ P PK TAP +T+++ T + L +T
Sbjct: 667 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 715
Query: 867 SPLVTSS 873
P T+S
Sbjct: 716 GPTSTTS 722
Score = 38.1 bits (87), Expect = 0.050
Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)
Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
P +P T S V T + K+ T+ H S E + + +A P + G
Sbjct: 754 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 804
Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
P +P + P T T K TT L + + A + + + + +++T + +
Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864
Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
Q+ S T L ++ V T K + +E +
Sbjct: 865 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 905
Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
N+PE+T + D+ ++ PKP P K K TS K P K K +P
Sbjct: 906 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 957
Query: 690 EPEKDFSEKAKPSP 703
P K S + +P
Sbjct: 958 TPRKMTSTMPELNP 971
Score = 33.9 bits (76), Expect = 0.95
Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
P + E + T+NK + + T + +T++ KEK TSA KE+ S S
Sbjct: 173 PNSDTSKETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSA---KETQSIEKTSAKDL 228
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
P+S +L + ++ K PA TT +P P P + + + + ++ +
Sbjct: 229 APTSKVL-AKPTPKAETTTKGPA---LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 284
Query: 1163 TRSDHNTSTSTKSLLPKE 1180
+ T+T + PKE
Sbjct: 285 PKEPAPTTTKSAPTTPKE 302
Score = 33.5 bits (75), Expect = 1.2
Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)
Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 803
++ +KN+ + K+P+PK VV + G T TST+
Sbjct: 108 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 149
Query: 804 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 863
V+ T P+ RP LP + + + S TV ++ ++ T+T TS
Sbjct: 150 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 204
Query: 864 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 913
T TS+ ++ + DL A + +AK T K KG
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 248
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 65.1 bits (157), Expect = 4e-10
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 123 CELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK 179
C+ C YH +C+ L SE E ++ CP+C+ A + T +T E L +L+
Sbjct: 2742 CDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLR 2798
Query: 180 -FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAK 238
KM P F +PV PDY I PMDL T+E+ +++ Y F+AD
Sbjct: 2799 SLQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMT 2854
Query: 239 WILHNCIIYNGGNHKLTQIAKVV 261
I NC YN + Q A+V+
Sbjct: 2855 KIFDNCRYYNPSDSPFYQCAEVL 2877
Score = 55.5 bits (132), Expect = 3e-07
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 162
D +C VCH+ G +LCCE C VYH +C++ L PE +W C C K+ V +C+
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449
Query: 163 SKAMTMLTIEQLSY 176
K + E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463
Score = 37.7 bits (86), Expect = 0.066
Identities = 52/238 (21%), Positives = 95/238 (39%), Gaps = 15/238 (6%)
Query: 740 DHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATT 799
++ ++ KN++E ++ S ++D KTP S T V + ++ ++ G T
Sbjct: 584 ENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTN 643
Query: 800 STSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTIT 859
+TS T+P+ + + P +++ ++ V + E S+ T
Sbjct: 644 ATSEE---TSPSEGRSPVGCLSETP----DSSNMAEKKVASELPQDVPEEPNKTCESSNT 696
Query: 860 LVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIY 919
T+T P + +S S S L SS + A + + S + + +E
Sbjct: 697 SATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKS 756
Query: 920 N-DLS------KNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSL 970
N +LS K +GST I RLR KL L Q+++ H E ++ L
Sbjct: 757 NGELSESPGAGKGASGST-RIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVL 813
Score = 37.0 bits (84), Expect = 0.11
Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)
Query: 660 NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 715
N E K L S+S A G +D P E D ++ PS P + + ++
Sbjct: 1605 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1659
Query: 716 TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 769
+ T + + S+ ES L D D +G KN+ E K + T +
Sbjct: 1660 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1718
Query: 770 TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 827
+TV + S V + + +S +T T++T TVT + +TG V
Sbjct: 1719 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1771
Query: 828 KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 887
+ V S TV +T S +T+ TLVTS V+ S V +
Sbjct: 1772 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1821
Query: 888 PIATASADVAADIAKYTSK 906
P T S K+ +K
Sbjct: 1822 PKKTRSGTALPSYRKFVTK 1840
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 65.1 bits (157), Expect = 4e-10
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 11/143 (7%)
Query: 123 CELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK 179
C+ C YH +C+ L SE E ++ CP+C+ A + T +T E L +L+
Sbjct: 2759 CDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLR 2815
Query: 180 -FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAK 238
KM P F +PV PDY I PMDL T+E+ +++ Y F+AD
Sbjct: 2816 SLQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMT 2871
Query: 239 WILHNCIIYNGGNHKLTQIAKVV 261
I NC YN + Q A+V+
Sbjct: 2872 KIFDNCRYYNPSDSPFYQCAEVL 2894
Score = 55.5 bits (132), Expect = 3e-07
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)
Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 162
D +C VCH+ G +LCCE C VYH +C++ L PE +W C C K+ V +C+
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449
Query: 163 SKAMTMLTIEQLSY 176
K + E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463
Score = 46.2 bits (108), Expect = 2e-04
Identities = 51/258 (19%), Positives = 104/258 (40%), Gaps = 16/258 (6%)
Query: 752 EPKEPS-PKQDVVGKTPPSTTVGSHSPPET-PVLTRSSAQTSAAGATATTSTSSTVTVTA 809
+P+ P+ P+ + TTV SH P E P +SS AA + ++ V
Sbjct: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRV 2343
Query: 810 PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST----VQQKEITQSPSTSTITLVTSTQ 865
+P+ T + RP P + +P Q V +++ +Q Q PS Q
Sbjct: 2344 QSPSQT-----RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398
Query: 866 SSPLVTSSG---SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 922
SS SSG + T+ S L I V A + + + +++ +
Sbjct: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIA--VPQLQQQVQVLSQIQSQVVAQI 2456
Query: 923 SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 982
+G +L I+I++ + ++ + ++ E Q ++Q RD+ + +
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516
Query: 983 KQLELEKQQAVDETKKKQ 1000
+Q+E++++ + + + +
Sbjct: 2517 QQIEIKREHTLQASNQSE 2534
Score = 37.0 bits (84), Expect = 0.11
Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)
Query: 660 NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 715
N E K L S+S A G +D P E D ++ PS P + + ++
Sbjct: 1479 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1533
Query: 716 TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 769
+ T + + S+ ES L D D +G KN+ E K + T +
Sbjct: 1534 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1592
Query: 770 TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 827
+TV + S V + + +S +T T++T TVT + +TG V
Sbjct: 1593 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1645
Query: 828 KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 887
+ V S TV +T S +T+ TLVTS V+ S V +
Sbjct: 1646 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1695
Query: 888 PIATASADVAADIAKYTSK 906
P T S K+ +K
Sbjct: 1696 PKKTRSGTALPSYRKFVTK 1714
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 17/107 (15%)
Query: 48 SSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRN 107
S N +S D STS + +K L + K++ E ++ D + QD
Sbjct: 325 SINSYSVSDGSTSRSSRSRKK-LRTTKKKKKGE---------EEVTAVDGYETDHQD--- 371
Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
YC VC + G+++ C+ CPR YH CL + PEG W CP CEK
Sbjct: 372 --YCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK 416
Score = 55.5 bits (132), Expect = 3e-07
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 99 DVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
D+ +D + +C VC G++LCC+ CP YH CL L P G+W CP C
Sbjct: 440 DLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRC 493
Score = 37.7 bits (86), Expect = 0.066
Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 36/242 (14%)
Query: 606 HSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN---PV 662
H ++E+ + D S++E ++K +P D + + + KE + ++ ++ P
Sbjct: 32 HPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPE 91
Query: 663 EIKEE----LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDS 718
++EE L+S S S+ K K P+ EK K K +++ + D+ DS
Sbjct: 92 FVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRK------EEEEEEDDDDDS 145
Query: 719 PTVHLGLDSDSESELVIDLG----------EDHSGREGRKNKKEPKEP--SPKQDVVGKT 766
+ S ++L+ D G ED+ K + P + K + +
Sbjct: 146 K------EPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVS 199
Query: 767 PPSTTVGS---HSPPETPVLTRSSAQTSAAGATATTSTSSTVTVT--APAPAATGSPVKK 821
+G+ P S A +AA A A S VT T AP P P++K
Sbjct: 200 KMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRK 259
Query: 822 QR 823
+
Sbjct: 260 AK 261
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 59.7 bits (143), Expect = 2e-08
Identities = 23/45 (51%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
YC VC + G+++ C+ CPR YH CL L PEG W CP CEK
Sbjct: 345 YCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEK 389
Score = 53.1 bits (126), Expect = 2e-06
Identities = 20/43 (46%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
+C VC G++LCC+ CP YH CL L P G+W CP C
Sbjct: 418 FCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460
Score = 35.0 bits (79), Expect = 0.43
Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Query: 638 EDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASE---KADPGAVKDKASPEPEKD 694
E G Q ++P V+ P + VE ++ K SPAS+ + + +KA P PE+
Sbjct: 1578 EKDPGAQKPRQPLEVQALPAALDRVESED--KHESPASKERAREERPEETEKAPPSPEQL 1635
Query: 695 FSEKAKPSPHPIKDKLKGK---DETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKK 751
E+ P I DKL+ DS + D+ +E + I+ ++ E + KK
Sbjct: 1636 PREEVLPEKEKILDKLELSLIHSRGDSSELRPD-DTKAEEKEPIETQQNGDKEEDDEGKK 1694
Query: 752 EPKE 755
E K+
Sbjct: 1695 EDKK 1698
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/45 (51%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
YC VC + G+++ C+ CPR YH CL L PEG W CP CEK
Sbjct: 381 YCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425
Score = 50.8 bits (120), Expect = 7e-06
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
YC VC G++LCC+ C YH CL L P G+W CP C
Sbjct: 458 YCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/45 (51%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
YC VC + G+++ C+ CPR YH CL L PEG W CP CEK
Sbjct: 381 YCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 425
Score = 50.8 bits (120), Expect = 7e-06
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
YC VC G++LCC+ C YH CL L P G+W CP C
Sbjct: 458 YCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 500
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 59.3 bits (142), Expect = 2e-08
Identities = 23/45 (51%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
YC VC + G+++ C+ CPR YH CL L PEG W CP CEK
Sbjct: 440 YCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEK 484
Score = 50.8 bits (120), Expect = 7e-06
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 110 YCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
YC VC G++LCC+ C YH CL L P G+W CP C
Sbjct: 517 YCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRC 559
Score = 37.4 bits (85), Expect = 0.086
Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)
Query: 596 ISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ------KSKNEPEDTEDKEGCQM--DK 647
+SE+ E D E+ E+ +++D + DD++ + D GC +
Sbjct: 17 VSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGPGHDRGRDRHSPPGCHLFPPP 76
Query: 648 EPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIK 707
P P P P K++++ A G K K P+ +K+ KP P K
Sbjct: 77 PPPPPPLPPPPPPPPPDKDDIRLLPSAL-----GVKKRKRGPKKQKE----NKPG-KPRK 126
Query: 708 DKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQ 760
K + +E G + D E G ++ GRK +++ +E K+
Sbjct: 127 RKKRDSEE------EFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKK 173
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 58.5 bits (140), Expect = 4e-08
Identities = 85/411 (20%), Positives = 146/411 (35%), Gaps = 44/411 (10%)
Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
+S+AS + + + + S S SP P+ ++ KT + S + S +
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS------PPRRRHRPSP 403
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLG-----------------I 593
+ + + +P P S R +SR ++ +T G +
Sbjct: 404 PATPPPKTRHSPTPQQS-NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVEL 462
Query: 594 NEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVK 653
+E ED + +DS + ++ S D S + ++ + + + +
Sbjct: 463 SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
Query: 654 KKPKPTNPVEIKEELKSTSPASEKA---DPGAVKDKASPEPEKDFSEKAKPSPHPIKDKL 710
P + ++ K TSP + P + + SP P + P+P P
Sbjct: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPP----- 577
Query: 711 KGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPST 770
+ T SP S I S R+ P P PK+ PP
Sbjct: 578 --RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPP--PPPKRRASPSPPPKR 633
Query: 771 TVGSHSPP----ETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 826
V SHSPP +PV R S S+ ++ + ST +P P SP + R
Sbjct: 634 RV-SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
Query: 827 PKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMS 877
+ P V+R +S+ Q+ + SPST I V+ T + + S S
Sbjct: 693 TSSSPPPVRR---GASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Score = 50.8 bits (120), Expect = 7e-06
Identities = 56/277 (20%), Positives = 101/277 (36%), Gaps = 33/277 (11%)
Query: 584 IESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC 643
+E K ++ +I ++ +++ D ED +K D + E + ++S++
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQD-EDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP 182
Query: 644 QMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSP 703
+ P ++K + + + +S SPA EK + K PEP E +
Sbjct: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE----KTPELPEPSVKVKEPSVQEA 238
Query: 704 HPIKDKLKGKD-----ETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEP----- 753
D LK E P+ + E E S R + P
Sbjct: 239 TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298
Query: 754 --------------KEPSPKQ--DVVGKTPPSTTVGS--HSPPETPVLTRSSAQTSAAGA 795
+ PSP++ +TPP H +PV R + S +G+
Sbjct: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358
Query: 796 TATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAP 832
++++S+S + + P T SP +K R L P + P
Sbjct: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395
Score = 47.4 bits (111), Expect = 8e-05
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 27/190 (14%)
Query: 624 SDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAV 683
S Q+ ++ T EP +KK P+ P ++ + S+ S +P A
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS-PQSVRR-VSSSRSVSGSPEPAAK 762
Query: 684 KDKASPEPEKDFSEKAKPSPH-PIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS 742
K A P P + S SP P+K K K T SP+ D +
Sbjct: 763 KPPAPPSPVQSQSPSTNWSPAVPVK---KAKSPTPSPSPPRNSDQEG------------- 806
Query: 743 GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTS 802
G K KK+ K+ K+D K H + ++A T AA A ATT+ +
Sbjct: 807 ---GGKKKKKKKDKKHKKDKKHKKHK-----KHKKEKAVAAAAAAAVTPAAIAAATTTLA 858
Query: 803 STVTVTAPAP 812
V AP P
Sbjct: 859 QEEPVAAPEP 868
Score = 34.3 bits (77), Expect = 0.73
Identities = 42/201 (20%), Positives = 63/201 (31%), Gaps = 33/201 (16%)
Query: 649 PSAVKKKPKPTNPVEIKEELKSTSPASEK---ADPGAVKDKASPEPEKDFSEKAKPSPHP 705
P ++ P P + S SP ++ + P K +ASP P P P
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643
Query: 706 IKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGK 765
+ + + H S S S R + NK+ P P+
Sbjct: 644 RSSPVTKRRSPSLSSKHRKGSSPSRST--------REARSPQPNKRHSPSPRPRAPQTSS 695
Query: 766 TPPSTTVGSHSPPET-------------------PVLTRSSAQTSAAGATATTSTSSTVT 806
+PP G+ S P+ P + +A S +S+ S
Sbjct: 696 SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG 755
Query: 807 VTAPA---PAATGSPVKKQRP 824
PA P A SPV+ Q P
Sbjct: 756 SPEPAAKKPPAPPSPVQSQSP 776
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 57.8 bits (138), Expect = 6e-08
Identities = 74/366 (20%), Positives = 132/366 (36%), Gaps = 18/366 (4%)
Query: 742 SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
+G E E E + +T +T GS + T T S T+ + A + +T
Sbjct: 549 TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605
Query: 802 SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
+ST + + TGS TA +ST + T S + S T+V
Sbjct: 606 ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656
Query: 862 TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
++T S +TS+ GS +T VS+ ++ ++T + + + G+ T I +
Sbjct: 657 STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS 716
Query: 921 DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
T ++I E + + T +E + + +A
Sbjct: 717 TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776
Query: 981 VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
+ E + K A+ K +F T+ + S S
Sbjct: 777 IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831
Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
T P A +E T T + S+ +++ST+ + + TAS + T+A +T GS
Sbjct: 832 TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891
Query: 1101 RETPSS 1106
T +S
Sbjct: 892 ETTTTS 897
Score = 48.5 bits (114), Expect = 4e-05
Identities = 116/563 (20%), Positives = 190/563 (33%), Gaps = 76/563 (13%)
Query: 400 DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
D N +A TA + + T + S G +S +D + +ST
Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659
Query: 458 SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS--------- 506
S T + E + AT S + S E S +TK GS
Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719
Query: 507 -------LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE-------- 551
++GS + + TT + + S T S + + A E
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779
Query: 552 ----LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHS 607
++ ++ ++T V S K + + F N + TI S A SE T V +
Sbjct: 780 SETTMASTIGSETTKVSTASSK--MTTVFTENSETTIASTTA-------SET--TTVSTA 828
Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEE 667
SE S + + + S+ TE E E S + T I E
Sbjct: 829 GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIGSE 882
Query: 668 LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
+ S + + + + + SE S + + +++ T S
Sbjct: 883 TTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA-----S 937
Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
SEL +G E E E + + +T ++T GS ET ++ +
Sbjct: 938 TEGSELTT---VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS----ETTTVSTAG 990
Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
++T+ TA+ S T TV++ TGS + T + + + T
Sbjct: 991 SETT----TASIEGSETTTVSS-----TGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041
Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
E T +T + T TST+ S T S + S ++ ADL T S + T+
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-- 1099
Query: 908 MDAIKGTMTEIYNDLSKNTTGST 930
T +Y SK TT ST
Sbjct: 1100 ----GSETTTVYITGSKTTTAST 1118
Score = 45.1 bits (105), Expect = 4e-04
Identities = 91/447 (20%), Positives = 166/447 (37%), Gaps = 52/447 (11%)
Query: 757 SPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQT---SAAGATATTSTSSTVTVTAPAPA 813
S K V TT+ S + ET ++ + ++T S AG+ TT+TS+ + T A +
Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA-S 857
Query: 814 ATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS 873
GS + T + + ++T E T + + + T TST+ S T+S
Sbjct: 858 TEGS----------ETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAS 907
Query: 874 --GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTI 931
GS T VS+ ++ A+ + S++ + T +E ++ + GS
Sbjct: 908 TEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT-TVSTTGSET---ITVSAEGSET 963
Query: 932 AEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQ 991
+ + E + + E T A + S +E +
Sbjct: 964 TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023
Query: 992 AVDETKKKQWC----ANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEA 1047
+ T+ + A + A++ T+ E ++ T S T +
Sbjct: 1024 TITSTEGSETTTVTTAGSETTAVYTTGSETTTTS--------TEGSETTTVSTTGSETTT 1075
Query: 1048 DAEVNTETLNKSSQGSSSSTQS-APSETASA--SKEKETSAEKSKESGSTLDLSGSRETP 1104
+ + ET S+ GS ++T S A SET + + K T+A +T+ + S ET
Sbjct: 1076 ASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS-ETT 1134
Query: 1105 SSILLGSNQGSVSKRCDKQPAYAP---------------TTTDHQPHPNYPAQKYHSRSN 1149
++ GS +V + + TTT + A S +
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETT 1194
Query: 1150 KSSWSSSDEKRGSTR-SDHNTSTSTKS 1175
+S + S+ ST S+ NT+ +T S
Sbjct: 1195 TASTAGSETTTASTSGSETNTACTTGS 1221
Score = 43.1 bits (100), Expect = 0.002
Identities = 76/370 (20%), Positives = 138/370 (37%), Gaps = 23/370 (6%)
Query: 765 KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
+T ++T GS + +P ++++ + + TTST+ + T + + +
Sbjct: 34 ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93
Query: 825 LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
TA + V S T + + + + T T T++ + + +++GS +T VS+V
Sbjct: 94 ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151
Query: 885 ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
++ A +AD A T M + T ++ +T GS + E +
Sbjct: 152 SETTTA-YTADSETTAASTTGSEMTTV---FTAGSETITPSTAGSETTTVSTAGSETTTV 207
Query: 945 QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQL---ELEKQQAVDETKKKQW 1001
+ + + E T A S + +E E D +
Sbjct: 208 STTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF 267
Query: 1002 CANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA------TAPQQEADAEVNT-- 1053
+ K + T+ + M S T A T A +EV T
Sbjct: 268 TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF 327
Query: 1054 ----ETLNKSSQGSSSSTQSAP-SETASAS-KEKETSAEKSKESGSTLDLSGSRETPSSI 1107
ET+ S+ GS ++T S SET +AS ETS + + S +T + ET ++
Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 1108 LLGSNQGSVS 1117
GS +VS
Sbjct: 388 TEGSEATTVS 397
Score = 42.0 bits (97), Expect = 0.003
Identities = 95/524 (18%), Positives = 182/524 (34%), Gaps = 34/524 (6%)
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
E + S A + + D + SE S + + +++ TV
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST--- 648
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
+DSE+ +V G + + ++ + + V TT S + ET ++ +
Sbjct: 649 TDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT 708
Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAAT-GSPVKKQRPLLPKETAPAVQRVVWNSSTVQ 845
++T+ + T++++T + A+T GS + T+ + +++
Sbjct: 709 GSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768
Query: 846 QKEITQSPSTSTITLVTSTQSSPL--VTSSGSMSTLVSSVNADLPIATASADVAADIAKY 903
E T + + T + ST S V+++ S T V + N++ IA+ +A ++
Sbjct: 769 SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828
Query: 904 TSKMMDAIKG-------TMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMK 956
S+ + A T TE + +T GS E + + +
Sbjct: 829 GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAST 888
Query: 957 HNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWN 1016
E T S +E+ + T+ + + +
Sbjct: 889 EGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVST 948
Query: 1017 TSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQS-APSETA 1075
T ++ T SA + + +ET S+ GS ++T S A SET
Sbjct: 949 TG--------------SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994
Query: 1076 SASKE-KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAY-----APT 1129
+AS E ET+ S S +T + ET + GS +V+ + A T
Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054
Query: 1130 TTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1173
TT + S + +S + + ST T+ ST
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098
Score = 41.6 bits (96), Expect = 0.005
Identities = 44/177 (24%), Positives = 79/177 (44%), Gaps = 18/177 (10%)
Query: 760 QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
+ V TT S + ET +++ ++T+ +TTS+ +TVT TA + T S V
Sbjct: 94 ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150
Query: 820 KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
+ ET A S+T + + + TIT T+ + V+++GS
Sbjct: 151 GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203
Query: 877 STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
+T VS+ ++ A+ + A+ + T+K+ A G+ T + S+ T ST
Sbjct: 204 TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAAST 258
Score = 41.6 bits (96), Expect = 0.005
Identities = 129/687 (18%), Positives = 230/687 (33%), Gaps = 46/687 (6%)
Query: 437 SGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASP 496
+G +S +D + ST S T + A+++ + S + + +T S
Sbjct: 589 AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648
Query: 497 ASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESV 556
++T S +GS + + + TT S TGS ++ + S SE+
Sbjct: 649 TDSETTMV-STTGSERTITSTEGSETTT----VSATGSETTVSTEGSGTTTVSITGSETT 703
Query: 557 QQQSTPVPLISPKRQIRSRFQLNLDK-TIESCKAQLGINEISEDVYTAVEHSDSEDSEKS 615
+ +T + I S + +I + E SE + E S++ + +
Sbjct: 704 KVSTT-----GSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTT 758
Query: 616 DSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPV--EIKEELKSTSP 673
S + + + + +E + E + V V E E +++
Sbjct: 759 GSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTT 818
Query: 674 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 733
ASE + P SE + + E T S++ +
Sbjct: 819 ASETTTVSTAGSETIPASTAG-SETTTTTSTEGSETTTASTEGSETTTASTESSETTTAT 877
Query: 734 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAA 793
I + EG + E S + TTV + T T S T+A+
Sbjct: 878 TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937
Query: 794 G-----ATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKE 848
T +T+ S T+TV+A T TA ST +
Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT----TASTAGSETTTVSTAGSET 993
Query: 849 ITQSPSTSTITLVTSTQS-SPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
T S S T V+ST S + V+++G+ +T+ S+ ++ T + A YT+
Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGS 1051
Query: 908 MDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMR 967
T TE + +TTGS +E + + E T +
Sbjct: 1052 ETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYIT 1109
Query: 968 QSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQA 1027
S +E + T + +F T+ +A
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTAST------TGSEMTTVFTTVSETTTVSTIGSEA 1163
Query: 1028 HWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQS---APSETASASKEKETS 1084
T SA + + +ET S+ GS ++T S + + TAS S + +
Sbjct: 1164 --------TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1215
Query: 1085 AEKSKESGSTLDLSGSRETPSSILLGS 1111
A + ST +GS ET ++ ++GS
Sbjct: 1216 ACTTGSETSTPSSAGS-ETNTAFIIGS 1241
Score = 40.0 bits (92), Expect = 0.013
Identities = 80/432 (18%), Positives = 150/432 (34%), Gaps = 53/432 (12%)
Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
+TT + T +L ++S T+A+ A + T+T S + +GS + +
Sbjct: 15 TTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE 74
Query: 829 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTST-QSSPLVTSSGSMSTLVSSVNADL 887
T + ++++ E T S + S T V+ T + +V++ GS +T S+ +++
Sbjct: 75 NTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSET 134
Query: 888 PIATASADVAADIAKYTSKMMDAIK------------GTMTEIYNDLSKNTTGSTIAEIR 935
+ + + ++ S+ A MT ++ S+ T ST
Sbjct: 135 TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGS-- 192
Query: 936 RLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDE 995
E + + + E T A S + +E K + V
Sbjct: 193 ----ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248
Query: 996 TKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTET 1055
+ A+ + NT++ E K+ T S T + A + +E
Sbjct: 249 AGSETTAASTEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEP 293
Query: 1056 LNKSSQGSSS-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
S+ GS + ST S+ T A+ + A +T+ +GS
Sbjct: 294 TMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSET 353
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
T +SI +GS + D TT + A S + S + S+ S
Sbjct: 354 TTASI-MGSETST-----DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVS 407
Query: 1163 TRSDHNTSTSTK 1174
T+T T+
Sbjct: 408 ITDSETTTTCTE 419
Score = 39.3 bits (90), Expect = 0.023
Identities = 78/432 (18%), Positives = 151/432 (34%), Gaps = 31/432 (7%)
Query: 755 EPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAA 814
EP+ + +T ++T+G P T V T SS T+ A + T +STV +
Sbjct: 292 EPTMASTMGSETTMASTIG---PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVST 348
Query: 815 TGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSG 874
TGS ++ ET+ +S+T + + + T T T + V+++G
Sbjct: 349 TGSET-TTASIMGSETST-------DSTTGSETTTASTEGSETTTASTEGSEATTVSTTG 400
Query: 875 SMSTLVSSVNADLPIATASAD----VAADIAKYTSKMMDAIKGTM--TEIYNDLSKNTTG 928
S +T VS +++ V+ + + T+ + + T+ T + +T G
Sbjct: 401 SETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEG 460
Query: 929 STIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMA------EMRQSLEQERDRLIAEVK 982
S + E + + + LE T S E ++
Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATG 520
Query: 983 KQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATA 1042
++ + + T + +T+ + E T A
Sbjct: 521 SEMTTVSTEGSENTTVSTTGSETTTV-------STTGLETTTTSTEGSEMTTVSTTGAET 573
Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
+ T S+ ++ ST + + TAS + + TSA + +T + S E
Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSS-E 632
Query: 1103 TPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGS 1162
T ++ GS +VS + + T ++ ++ + S + S E G+
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGT 692
Query: 1163 TRSDHNTSTSTK 1174
T S +TK
Sbjct: 693 TTVSITGSETTK 704
Score = 38.9 bits (89), Expect = 0.029
Identities = 148/790 (18%), Positives = 254/790 (32%), Gaps = 83/790 (10%)
Query: 440 TGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPAST 499
TG ++ S +TNS+ + + V A + T+ SE + + S + AST
Sbjct: 110 TGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAAST 169
Query: 500 KTGQ------AGSLSGSPKPFSPQLSAPITTKTDKT--STTGSILNLNLDRSKAEMDLKE 551
+ AGS + +P + + T ++ T STTGS S A +
Sbjct: 170 TGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTT---ASTAHSETTA 226
Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVY---TAVEHSD 608
S ++ ++T V + + + + E + E S+ T E +
Sbjct: 227 AS-TMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTA 285
Query: 609 SEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEEL 668
+ + + S S+ S PE T K + + + + E
Sbjct: 286 ASTTGSEPTMASTMGSETTMASTIGPETT--KVSTASSEVTTVFAAGSETIRASTVGSET 343
Query: 669 KSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL-GLDS 727
+ S + ++ + SE S + + +++ TV G ++
Sbjct: 344 TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403
Query: 728 ------DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS-TTVGSHSPPET 780
DSE+ G + + + + + T S TT S ET
Sbjct: 404 TTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSET 463
Query: 781 PVLTRSSAQTSAAGATAT-TSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVW 839
+T + ++T A T + T+T+S + GS + TA +
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEM 523
Query: 840 NSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPI------AT 891
+ + + E T +T + T ST T+S GS T VS+ A+ T
Sbjct: 524 TTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT 583
Query: 892 ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQE 951
+A A S T S +TTGS E +
Sbjct: 584 TAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSET 643
Query: 952 LSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011
+ + E TM S +R I + ET + +I
Sbjct: 644 TTVSTTDSETTMVSTTGS-----ERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSIT 698
Query: 1012 YCCWNTSYCDYPCQQAHWPEHMK-SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSA 1070
E K S T S T +E+ T ++ S+ +++ST+ +
Sbjct: 699 -----------------GSETTKVSTTGSETTITSTEGSEITTASIT-GSETTTASTEGS 740
Query: 1071 PSETASASKEKETSAEKSKESGSTLDLSGSRETPSSIL---------LGSNQGSVSKRCD 1121
+ TAS + TSA + +T + S T +SI+ +GS VS
Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800
Query: 1122 KQ---------------PAYAPTTTDHQPHPNYPAQKYHSR-SNKSSWSSSDEKRGSTRS 1165
K A TT PA S + +S S+ ST
Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860
Query: 1166 DHNTSTSTKS 1175
T+ ST+S
Sbjct: 861 SETTTASTES 870
Score = 37.0 bits (84), Expect = 0.11
Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)
Query: 432 SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
S+ + TG + + S + S + + + + + T ++S+ + F +
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
S + AST + ++S + P +A T T TST GS + + S+
Sbjct: 810 SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868
Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
E SE+ +T + S + + E + E SE T V + SE
Sbjct: 869 ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922
Query: 611 DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
+ S + SE + + S+ T E + E S + T
Sbjct: 923 TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981
Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
E + S A + +++ + SE S + + + +++ TV
Sbjct: 982 ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038
Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
+ SE+ V G + + ++ + + T +TTV + T T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098
Query: 785 RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
S T+ + T+T+ST A + T S + T V V ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156
Query: 845 QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
E T S + + TST+ S T+S GS +T S+ ++ A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Score = 35.8 bits (81), Expect = 0.25
Identities = 34/156 (21%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 1034 KSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE-KETSAEKSKESG 1092
++ T S + A + + +ET S+ GS ++ +A SET +AS E ET+ +++S
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK 272
Query: 1093 STLDLSGSRETPSSILLGSN---QGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSN 1149
+T + ET ++ GS ++ P TT + + + +
Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF-AAGS 331
Query: 1150 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDT 1185
++ +S+ +T S + T+T S++ E+ D+
Sbjct: 332 ETIRASTVGSETTTVSTTGSETTTASIMGSETSTDS 367
Score = 33.9 bits (76), Expect = 0.95
Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 763 VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
V +T +T+GS + T T S T+A+ A + T+T+ST + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 816 GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 872
GS + + P+ N++ + E T + + S T T +T ++++ + +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269
Query: 873 SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
+ + ++V++ + T + DV+ I T+ M + T T +
Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313
Score = 33.9 bits (76), Expect = 0.95
Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)
Query: 729 SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
SE+ V +G + + G E E E + +T ++T GS
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210
Query: 776 SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
S T T S T ++ + T T+ +ST ++ A + TGS +
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270
Query: 822 QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
T + V+ ++ V + IT +P + T T T +S VT + M S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330
Query: 882 SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
+ + +P I TS + + G + + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369
Score = 33.1 bits (74), Expect = 1.6
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 3/133 (2%)
Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGS-PVKKQRPLLP 827
+TTV + S T T S T+ + T+T ST+ A +A GS
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 828 KETAPAVQRVVWNSSTVQQKEITQSPSTS-TITLVTSTQSSPLVTSSGSMSTLVSSVNAD 886
TA +ST + T S S S T T T+ + +S+GS + + ++
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1242
Query: 887 LPIA-TASADVAA 898
IA TAS + A
Sbjct: 1243 TTIASTASLEPTA 1255
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 55.8 bits (133), Expect = 2e-07
Identities = 67/307 (21%), Positives = 112/307 (36%), Gaps = 46/307 (14%)
Query: 111 CWVCHREGQVLCCEL-CPRVYHAKCLRLTSEPEGDWFCPECEK--ITVAECIETQSKAMT 167
C C + G++L CE C +H +CL LT P G + C EC T C ++
Sbjct: 1277 CQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFICNECRTGIHTCFVCKQSGEDVKR 1336
Query: 168 MLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMY 227
L + + +QK P T K H + +P ++ + K +
Sbjct: 1337 CLLPLCGKFYHEECVQKY--PPTVMQNKGFRCSLHICITCHAANPANV-SASKGRLMRCV 1393
Query: 228 GCTEAFLAD-------AKWILHNCIIYNGG--------NHKLTQIAKVVIKICEHEMNEI 272
C A+ A+ +K + N II NH+ ++ + +
Sbjct: 1394 RCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCC 1453
Query: 273 EVCPECYLAACQKRD----NWFCEPCS---NPH--PLVWAKLKGFPFWPAK--------- 314
+ CP + C D NW+C C PH +VW K+ + +WPA+
Sbjct: 1454 DSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPS 1513
Query: 315 ---ALRDKDGQVDARFFGQHDRAWVPINNCY-LMSKEIPFSVKKTKSI---FNSAMQEME 367
+R G+ FFG +D W + M ++ K K + + A+QE
Sbjct: 1514 NIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAA 1573
Query: 368 VYVENIR 374
E ++
Sbjct: 1574 ARFEELK 1580
Score = 54.7 bits (130), Expect = 5e-07
Identities = 19/45 (42%), Positives = 30/45 (66%), Gaps = 1/45 (2%)
Query: 107 NDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECE 151
N +C+VC G +LCC+ CP +H +CL + PEG+W+C +C+
Sbjct: 1437 NVSWCFVCSEGGSLLCCDSCPAAFHRECLNI-DIPEGNWYCNDCK 1480
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Query: 111 CWVCHREGQVLCCEL--CPRVYHAKCLRLTSEPEGDWFCP 148
C+ C GQ++ C+ CP+VYHA CL LT P G W CP
Sbjct: 1852 CFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWECP 1891
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,683,642
Number of Sequences: 37866
Number of extensions: 2517095
Number of successful extensions: 24997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 339
Number of HSP's successfully gapped in prelim test: 1145
Number of HSP's that attempted gapping in prelim test: 14096
Number of HSP's gapped (non-prelim): 8038
length of query: 1188
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1075
effective length of database: 13,968,660
effective search space: 15016309500
effective search space used: 15016309500
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.