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Search of human proteins with 33620747
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33620747 myelin expression factor 2 [Homo sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33620747 myelin expression factor 2 [Homo sapiens] 1221 0.0
gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a ... 500 e-141
gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b... 449 e-126
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 77 3e-14
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 76 1e-13
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 76 1e-13
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 76 1e-13
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 76 1e-13
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 74 4e-13
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [... 74 5e-13
gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2 ... 74 5e-13
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 73 7e-13
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 73 7e-13
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 72 1e-12
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ... 72 1e-12
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 71 2e-12
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ... 71 3e-12
gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4... 70 7e-12
gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1 ... 69 2e-11
gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2... 69 2e-11
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 68 2e-11
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 66 1e-10
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 65 1e-10
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 65 1e-10
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 65 2e-10
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 64 4e-10
gi|238776833 THO complex 4 [Homo sapiens] 64 5e-10
gi|55956899 keratin 9 [Homo sapiens] 61 3e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 59 2e-08
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 58 3e-08
>gi|33620747 myelin expression factor 2 [Homo sapiens]
Length = 600
Score = 1221 bits (3159), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESA 60
MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESA
Sbjct: 1 MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESA 60
Query: 61 KEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLM 120
KEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLM
Sbjct: 61 KEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLM 120
Query: 121 REKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGE 180
REKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGE
Sbjct: 121 REKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGE 180
Query: 181 NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANL 240
NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANL
Sbjct: 181 NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANL 240
Query: 241 DFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD 300
DFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD
Sbjct: 241 DFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD 300
Query: 301 RPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLG 360
RPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLG
Sbjct: 301 RPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLG 360
Query: 361 PGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG 420
PGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG
Sbjct: 361 PGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG 420
Query: 421 DIGINRGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM 480
DIGINRGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM
Sbjct: 421 DIGINRGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM 480
Query: 481 SSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLK 540
SSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLK
Sbjct: 481 SSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLK 540
Query: 541 EKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA 600
EKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA
Sbjct: 541 EKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA 600
>gi|14141152 heterogeneous nuclear ribonucleoprotein M isoform a
[Homo sapiens]
Length = 730
Score = 500 bits (1288), Expect = e-141
Identities = 316/710 (44%), Positives = 394/710 (55%), Gaps = 174/710 (24%)
Query: 51 GVKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYD 110
G K E + A+ EK KEK+ + NRF PY+ R R FI+NIP+D
Sbjct: 35 GPKGEGERPAQNEKR--KEKNI-KRGGNRFEPYANPTK----------RYRAFITNIPFD 81
Query: 111 MKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRP 170
+KWQ++KDL++EKVGEVTYVEL DAEGKSRGC VVEFK EE +KKA E +NK+ LSGRP
Sbjct: 82 VKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP 141
Query: 171 LNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGR 230
L +KEDPDGE+ARRA+Q+ + G + G G++ +PPSILNNPNIP E+I LQAGR
Sbjct: 142 LKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGR 201
Query: 231 LGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI 290
LGST+FVANLD+KVGWKKLKEVFS+AG V RADI EDKDGKSRG+GTVTFEQ+IEAVQAI
Sbjct: 202 LGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAI 261
Query: 291 SMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGL------------ 338
SMFNGQ LFDRPMHVKMD++++P ++ + + QLP GLGGIGMGL
Sbjct: 262 SMFNGQLLFDRPMHVKMDERALPKGDFFPPE-RPQQLPHGLGGIGMGLGPGGQPIDANHL 320
Query: 339 ---------GPGGQPISASQLNI----------GGVMGNLGPGGMGMD------------ 367
GP G + I GG M N+G G GM+
Sbjct: 321 NKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNAL 380
Query: 368 ------------------------GPGF-----GGMNRIGGGIGFG----GLE------A 388
GPG GM R+G G+G G G E
Sbjct: 381 KRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLV 440
Query: 389 MNSMGGF----GGVGRMGELYRGAMTSSMER--------DFGRGDIGINRGFG------- 429
M+ MG G+ RMG L M SS+ER G +G GFG
Sbjct: 441 MDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAP 500
Query: 430 -----DSFGRLGSAM--IGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM-- 480
+ R+GS + +G R+G S V +G+ G+ M V M GL+RM
Sbjct: 501 IDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGA 560
Query: 481 -------------------------SSSFDRMGP-------------------GIGAILE 496
++S +RMGP G GA +
Sbjct: 561 NNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFD 620
Query: 497 RSIDMDRGFLSGPMGS------GMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVM 550
R+I+M+RG G G + K QIFVRNLPFD TW+ LK+KF++CGHV+
Sbjct: 621 RAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVL 680
Query: 551 FAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA 600
+A+IKMENGKSKGCG V+F+SPE AE+ACR+MNG+K+SGREIDVR+DRNA
Sbjct: 681 YADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA 730
>gi|157412270 heterogeneous nuclear ribonucleoprotein M isoform b
[Homo sapiens]
Length = 691
Score = 449 bits (1154), Expect = e-126
Identities = 298/710 (41%), Positives = 370/710 (52%), Gaps = 213/710 (30%)
Query: 51 GVKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYD 110
G K E + A+ EK KEK+ + NRF PY+ R R FI+NIP+D
Sbjct: 35 GPKGEGERPAQNEKR--KEKNI-KRGGNRFEPYANPTK----------RYRAFITNIPFD 81
Query: 111 MKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRP 170
+KWQ++KDL++EKVGEVTYVEL DAEGKSRGC VVEFK EE +KKA E +NK+ LSGRP
Sbjct: 82 VKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP 141
Query: 171 LNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGR 230
L +KEDPDGE+ARRA+Q+ AGR
Sbjct: 142 LKVKEDPDGEHARRAMQK---------------------------------------AGR 162
Query: 231 LGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI 290
LGST+FVANLD+KVGWKKLKEVFS+AG V RADI EDKDGKSRG+GTVTFEQ+IEAVQAI
Sbjct: 163 LGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAI 222
Query: 291 SMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGL------------ 338
SMFNGQ LFDRPMHVKMD++++P ++ + + QLP GLGGIGMGL
Sbjct: 223 SMFNGQLLFDRPMHVKMDERALPKGDFFPPE-RPQQLPHGLGGIGMGLGPGGQPIDANHL 281
Query: 339 ---------GPGGQPISASQLNI----------GGVMGNLGPGGMGMD------------ 367
GP G + I GG M N+G G GM+
Sbjct: 282 NKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNAL 341
Query: 368 ------------------------GPGF-----GGMNRIGGGIGFG----GLE------A 388
GPG GM R+G G+G G G E
Sbjct: 342 KRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLV 401
Query: 389 MNSMGGF----GGVGRMGELYRGAMTSSMER--------DFGRGDIGINRGFG------- 429
M+ MG G+ RMG L M SS+ER G +G GFG
Sbjct: 402 MDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAP 461
Query: 430 -----DSFGRLGSAM--IGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM-- 480
+ R+GS + +G R+G S V +G+ G+ M V M GL+RM
Sbjct: 462 IDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGA 521
Query: 481 -------------------------SSSFDRMGP-------------------GIGAILE 496
++S +RMGP G GA +
Sbjct: 522 NNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFD 581
Query: 497 RSIDMDRGFLSGPMGS------GMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVM 550
R+I+M+RG G G + K QIFVRNLPFD TW+ LK+KF++CGHV+
Sbjct: 582 RAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVL 641
Query: 551 FAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA 600
+A+IKMENGKSKGCG V+F+SPE AE+ACR+MNG+K+SGREIDVR+DRNA
Sbjct: 642 YADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA 691
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 77.4 bits (189), Expect = 3e-14
Identities = 60/237 (25%), Positives = 107/237 (45%), Gaps = 34/237 (14%)
Query: 85 KDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
++ G K+ PN V+I N DM + +KDL K G V++ D GKS+G G
Sbjct: 179 REAELGARAKEFPN---VYIKNFGEDMDDERLKDLFG-KFGPALSVKVMTDESGKSKGFG 234
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSG 204
V F+ E +KA++ MN +L+G+ + + + L+RT
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQ------------ 282
Query: 205 LMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADI 264
+ I + NL +V NLD + ++L++ FS GT+ A +
Sbjct: 283 --------MKQDRITRYQVVNL---------YVKNLDDGIDDERLRKAFSPFGTITSAKV 325
Query: 265 KEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHD 321
+ G+S+G G V F EA +A++ NG+ + +P++V + + + Y +++
Sbjct: 326 MME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNE 381
Score = 53.1 bits (126), Expect = 7e-07
Identities = 44/214 (20%), Positives = 86/214 (40%), Gaps = 41/214 (19%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
+F+ N+ + +A+ D + G + + D G S+G G V F+ E ++A++ M
Sbjct: 101 IFVKNLDKSINNKALYDTV-SAFGNILSCNVVCDENG-SKGYGFVHFETHEAAERAIKKM 158
Query: 162 NKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPE 221
N L+GR + + + + L FP ++ + G + +
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDD-------------- 204
Query: 222 VISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFE 281
++LK++F G + D+ GKS+G G V+FE
Sbjct: 205 -------------------------ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239
Query: 282 QAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHE 315
+ +A +A+ NG+ L + ++V K V +
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273
Score = 53.1 bits (126), Expect = 7e-07
Identities = 28/72 (38%), Positives = 44/72 (61%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
++V+NL + ++L++ FS G + A++ ME G+SKG G V F SPE A KA MNG
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 585 IKISGREIDVRL 596
++ + + V L
Sbjct: 356 RIVATKPLYVAL 367
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/71 (35%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKM-ENGKSKGCGTVRFDSPESAEKACRIMN 583
++++N D+ ++LK+ F + G + ++ E+GKSKG G V F+ E A+KA MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 584 GIKISGREIDV 594
G +++G++I V
Sbjct: 253 GKELNGKQIYV 263
Score = 48.9 bits (115), Expect = 1e-05
Identities = 24/70 (34%), Positives = 43/70 (61%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
IFV+NL + + L + S G+++ + + SKG G V F++ E+AE+A + MNG
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 585 IKISGREIDV 594
+ ++GR++ V
Sbjct: 161 MLLNGRKVFV 170
Score = 32.3 bits (72), Expect = 1.3
Identities = 46/212 (21%), Positives = 77/212 (36%), Gaps = 20/212 (9%)
Query: 35 PAEAEKQQPQHSSSSNG---VKMENDESAKEEKSDLKEKSTGSK-----KANRFHPYSKD 86
PA + K S S G V E E A++ ++ K K +A + +
Sbjct: 216 PALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTE 275
Query: 87 KNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKV----GEVTYVELFKDAEGKSRG 142
+ K R + N+ I D K G +T ++ + G+S+G
Sbjct: 276 LKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG-GRSKG 334
Query: 143 CGVVEFKDEEFVKKALETMNKYDLSGRPLNI-----KEDPDGENARRALQRTGG--SFPG 195
G V F E KA+ MN ++ +PL + KE+ +QR + P
Sbjct: 335 FGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNEYMQRMASVRAVPN 394
Query: 196 GHVPDMGSGLMNLPPSILNNPNIPPEVISNLQ 227
P G + +P + + PP I+ L+
Sbjct: 395 QRAPPSGYFMTAVPQTQNHAAYYPPSQIARLR 426
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/236 (25%), Positives = 111/236 (47%), Gaps = 35/236 (14%)
Query: 85 KDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
K++ + G K N V+I N ++ +++K+L + G+ V++ +D GKS+G G
Sbjct: 177 KEREAELGAKAKEFTN-VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRDPNGKSKGFG 234
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSG 204
V ++ E KA+E MN ++SG+ + + + L+R
Sbjct: 235 FVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR---------------- 278
Query: 205 LMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADI 264
+ E IS Q G +++ NLD + +KL++ FS G++ A +
Sbjct: 279 ---------KFEQLKQERISRYQ----GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 265 KEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSH 320
+ DG+S+G G V F EA +A++ NG+ + +P++V + + EE ++H
Sbjct: 326 MLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRK---EERKAH 377
Score = 57.0 bits (136), Expect = 5e-08
Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Query: 515 RERIGS-KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPE 573
+ERI +G ++++NL + +KL+++FS G + A++ +E+G+SKG G V F SPE
Sbjct: 285 QERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPE 344
Query: 574 SAEKACRIMNGIKISGREIDVRL 596
A KA MNG + + + V L
Sbjct: 345 EATKAVTEMNGRIVGSKPLYVAL 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
Query: 518 IGSKGNQ---IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME-NGKSKGCGTVRFDSPE 573
+G+K + ++++N ++ + LKE FSQ G + ++ + NGKSKG G V ++ E
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHE 242
Query: 574 SAEKACRIMNGIKISGREIDV 594
A KA MNG +ISG+ I V
Sbjct: 243 DANKAVEEMNGKEISGKIIFV 263
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/70 (30%), Positives = 42/70 (60%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
+F++NL + + L + FS G+++ ++ + SKG V F++ E+A+KA MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 585 IKISGREIDV 594
+ ++ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 46/167 (27%)
Query: 139 KSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHV 198
+S G V F+ ++AL+TMN + G+P+ I + R+
Sbjct: 50 RSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRK-------------- 95
Query: 199 PDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGT 258
SG+ N +F+ NLD + K L + FS G
Sbjct: 96 ----SGVGN---------------------------VFIKNLDKSIDNKALYDTFSAFGN 124
Query: 259 VKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHV 305
+ + D++G S+G V FE A +AI NG L DR + V
Sbjct: 125 ILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Score = 37.0 bits (84), Expect = 0.052
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIM 582
++V +L D+T L EKFS G V+ + M +S G V F P AE+A M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 583 NGIKISGREIDV 594
N I G+ I +
Sbjct: 73 NFDVIKGKPIRI 84
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 125 GEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNI-----KEDPDG 179
G +T ++ + +G+S+G G V F E KA+ MN + +PL + KE+
Sbjct: 318 GSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKA 376
Query: 180 ENARRALQRTGG 191
+ +QR G
Sbjct: 377 HLTNQYMQRVAG 388
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/236 (25%), Positives = 111/236 (47%), Gaps = 35/236 (14%)
Query: 85 KDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
K++ + G K N V+I N ++ +++K+L + G+ V++ +D GKS+G G
Sbjct: 177 KEREAELGAKAKEFTN-VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRDPNGKSKGFG 234
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSG 204
V ++ E KA+E MN ++SG+ + + + L+R
Sbjct: 235 FVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR---------------- 278
Query: 205 LMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADI 264
+ E IS Q G +++ NLD + +KL++ FS G++ A +
Sbjct: 279 ---------KFEQLKQERISRYQ----GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 265 KEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSH 320
+ DG+S+G G V F EA +A++ NG+ + +P++V + + EE ++H
Sbjct: 326 MLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRK---EERKAH 377
Score = 57.0 bits (136), Expect = 5e-08
Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Query: 515 RERIGS-KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPE 573
+ERI +G ++++NL + +KL+++FS G + A++ +E+G+SKG G V F SPE
Sbjct: 285 QERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPE 344
Query: 574 SAEKACRIMNGIKISGREIDVRL 596
A KA MNG + + + V L
Sbjct: 345 EATKAVTEMNGRIVGSKPLYVAL 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
Query: 518 IGSKGNQ---IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME-NGKSKGCGTVRFDSPE 573
+G+K + ++++N ++ + LKE FSQ G + ++ + NGKSKG G V ++ E
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHE 242
Query: 574 SAEKACRIMNGIKISGREIDV 594
A KA MNG +ISG+ I V
Sbjct: 243 DANKAVEEMNGKEISGKIIFV 263
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/70 (30%), Positives = 42/70 (60%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
+F++NL + + L + FS G+++ ++ + SKG V F++ E+A+KA MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 585 IKISGREIDV 594
+ ++ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 46/167 (27%)
Query: 139 KSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHV 198
+S G V F+ ++AL+TMN + G+P+ I + R+
Sbjct: 50 RSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRK-------------- 95
Query: 199 PDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGT 258
SG+ N +F+ NLD + K L + FS G
Sbjct: 96 ----SGVGN---------------------------VFIKNLDKSIDNKALYDTFSAFGN 124
Query: 259 VKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHV 305
+ + D++G S+G V FE A +AI NG L DR + V
Sbjct: 125 ILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Score = 37.0 bits (84), Expect = 0.052
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIM 582
++V +L D+T L EKFS G V+ + M +S G V F P AE+A M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 583 NGIKISGREIDV 594
N I G+ I +
Sbjct: 73 NFDVIKGKPIRI 84
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 125 GEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNI-----KEDPDG 179
G +T ++ + +G+S+G G V F E KA+ MN + +PL + KE+
Sbjct: 318 GSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKA 376
Query: 180 ENARRALQRTGG 191
+ +QR G
Sbjct: 377 HLTNQYMQRVAG 388
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/236 (25%), Positives = 111/236 (47%), Gaps = 35/236 (14%)
Query: 85 KDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
K++ + G K N V+I N ++ +++K+L + G+ V++ +D GKS+G G
Sbjct: 177 KEREAELGAKAKEFTN-VYIKNFGEEVDDESLKELFSQ-FGKTLSVKVMRDPNGKSKGFG 234
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSG 204
V ++ E KA+E MN ++SG+ + + + L+R
Sbjct: 235 FVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKR---------------- 278
Query: 205 LMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADI 264
+ E IS Q G +++ NLD + +KL++ FS G++ A +
Sbjct: 279 ---------KFEQLKQERISRYQ----GVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 265 KEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSH 320
+ DG+S+G G V F EA +A++ NG+ + +P++V + + EE ++H
Sbjct: 326 MLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRK---EERKAH 377
Score = 57.0 bits (136), Expect = 5e-08
Identities = 31/83 (37%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Query: 515 RERIGS-KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPE 573
+ERI +G ++++NL + +KL+++FS G + A++ +E+G+SKG G V F SPE
Sbjct: 285 QERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPE 344
Query: 574 SAEKACRIMNGIKISGREIDVRL 596
A KA MNG + + + V L
Sbjct: 345 EATKAVTEMNGRIVGSKPLYVAL 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 4/81 (4%)
Query: 518 IGSKGNQ---IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME-NGKSKGCGTVRFDSPE 573
+G+K + ++++N ++ + LKE FSQ G + ++ + NGKSKG G V ++ E
Sbjct: 183 LGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHE 242
Query: 574 SAEKACRIMNGIKISGREIDV 594
A KA MNG +ISG+ I V
Sbjct: 243 DANKAVEEMNGKEISGKIIFV 263
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/70 (30%), Positives = 42/70 (60%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
+F++NL + + L + FS G+++ ++ + SKG V F++ E+A+KA MNG
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 585 IKISGREIDV 594
+ ++ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 40.8 bits (94), Expect = 0.004
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 46/167 (27%)
Query: 139 KSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHV 198
+S G V F+ ++AL+TMN + G+P+ I + R+
Sbjct: 50 RSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRK-------------- 95
Query: 199 PDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGT 258
SG+ N +F+ NLD + K L + FS G
Sbjct: 96 ----SGVGN---------------------------VFIKNLDKSIDNKALYDTFSAFGN 124
Query: 259 VKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHV 305
+ + D++G S+G V FE A +AI NG L DR + V
Sbjct: 125 ILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFV 170
Score = 37.0 bits (84), Expect = 0.052
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIM 582
++V +L D+T L EKFS G V+ + M +S G V F P AE+A M
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 583 NGIKISGREIDV 594
N I G+ I +
Sbjct: 73 NFDVIKGKPIRI 84
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 125 GEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNI-----KEDPDG 179
G +T ++ + +G+S+G G V F E KA+ MN + +PL + KE+
Sbjct: 318 GSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKA 376
Query: 180 ENARRALQRTGG 191
+ +QR G
Sbjct: 377 HLTNQYMQRVAG 388
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 75.9 bits (185), Expect = 1e-13
Identities = 59/223 (26%), Positives = 105/223 (47%), Gaps = 32/223 (14%)
Query: 85 KDKNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
KD+ + K N V+I N DM + +KD+ K G+ V++ D+ GKS+G G
Sbjct: 176 KDREAELRSKASEFTN-VYIKNFGGDMDDERLKDVF-SKYGKTLSVKVMTDSSGKSKGFG 233
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSG 204
V F E KKA+E MN D++G+ + + A++ ++R + M
Sbjct: 234 FVSFDSHEAAKKAVEEMNGRDINGQLIFV------GRAQKKVERQ------AELKQMFEQ 281
Query: 205 LMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADI 264
L E I Q G +++ NLD + +KL+ FS G++ R +
Sbjct: 282 LKR-------------ERIRGCQ----GVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKV 324
Query: 265 KEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKM 307
++ +G+S+G G + F +A +A++ NG+ L +P+ + +
Sbjct: 325 MQE-EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIAL 366
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/83 (36%), Positives = 49/83 (59%), Gaps = 1/83 (1%)
Query: 515 RERI-GSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPE 573
RERI G +G +++++NL + +KL+ +FS G + ++ E G+SKG G + F SPE
Sbjct: 284 RERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPE 343
Query: 574 SAEKACRIMNGIKISGREIDVRL 596
A KA MNG + + + + L
Sbjct: 344 DATKAMTEMNGRILGSKPLSIAL 366
Score = 52.8 bits (125), Expect = 9e-07
Identities = 29/76 (38%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
Query: 520 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMEN-GKSKGCGTVRFDSPESAEKA 578
S+ ++++N D+ ++LK+ FS+ G + ++ ++ GKSKG G V FDS E+A+KA
Sbjct: 187 SEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKA 246
Query: 579 CRIMNGIKISGREIDV 594
MNG I+G+ I V
Sbjct: 247 VEEMNGRDINGQLIFV 262
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/214 (19%), Positives = 82/214 (38%), Gaps = 41/214 (19%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
VFI N+ + + + + G++ ++ D +G S+G V F+++ +A+E M
Sbjct: 100 VFIKNLDKSIDNKTLYEHF-SAFGKILSSKVMSDDQG-SKGYAFVHFQNQSAADRAIEEM 157
Query: 162 NKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPE 221
N L G + + + ++ L+ F ++ + G + +
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDD-------------- 203
Query: 222 VISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFE 281
++LK+VFS G + D GKS+G G V+F+
Sbjct: 204 -------------------------ERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFD 238
Query: 282 QAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHE 315
A +A+ NG+ + + + V K V +
Sbjct: 239 SHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQ 272
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
+F++NL + + L E FS G ++ +++ ++ SKG V F + +A++A MNG
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNG 159
Query: 585 IKISGREIDV-----RLDRNA 600
+ G ++ V R DR A
Sbjct: 160 KLLKGCKVFVGRFKNRKDREA 180
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 73.9 bits (180), Expect = 4e-13
Identities = 56/206 (27%), Positives = 99/206 (48%), Gaps = 31/206 (15%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
VF+ NI D+ + +K+L E G V++ +DA GKS+G G V ++ E +KA+ +
Sbjct: 201 VFVKNIGDDIDDEKLKELFCE-YGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDL 259
Query: 162 NKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPE 221
+ + G+ L + A++ ++R + ++ L L + PP
Sbjct: 260 HGKSIDGKVLYVGR------AQKKIER---------LAELRRRFERLR---LKEKSRPP- 300
Query: 222 VISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFE 281
G I++ NLD + +KLKE FS G++ RA + + G+ +G G V F
Sbjct: 301 ----------GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-GQGKGFGVVCFS 349
Query: 282 QAIEAVQAISMFNGQFLFDRPMHVKM 307
EA +A+ NG+ + +P+HV +
Sbjct: 350 SFEEATKAVDEMNGRIVGSKPLHVTL 375
Score = 55.8 bits (133), Expect = 1e-07
Identities = 31/83 (37%), Positives = 47/83 (56%)
Query: 514 MRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPE 573
++E+ G I+++NL + +KLKE+FS G + A++ ME G+ KG G V F S E
Sbjct: 293 LKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFE 352
Query: 574 SAEKACRIMNGIKISGREIDVRL 596
A KA MNG + + + V L
Sbjct: 353 EATKAVDEMNGRIVGSKPLHVTL 375
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/82 (35%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Query: 514 MRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE-IKMENGKSKGCGTVRFDSP 572
+R R + +FV+N+ D+ +KLKE F + G + I+ +GKSKG G VR+++
Sbjct: 190 VRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETH 249
Query: 573 ESAEKACRIMNGIKISGREIDV 594
E+A+KA ++G I G+ + V
Sbjct: 250 EAAQKAVLDLHGKSIDGKVLYV 271
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 515 RERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPES 574
R R GN IF++NL + + L FS G+++ ++ ++ SKG V FDS +
Sbjct: 99 RLRKSGVGN-IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAA 157
Query: 575 AEKACRIMNGIKISGREIDV 594
A +A MNG++++ R++ V
Sbjct: 158 ANRAIWHMNGVRLNNRQVYV 177
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/80 (27%), Positives = 41/80 (51%)
Query: 233 STIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISM 292
+ +FV N+ + +KLKE+F G + + D GKS+G G V +E A +A+
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258
Query: 293 FNGQFLFDRPMHVKMDDKSV 312
+G+ + + ++V K +
Sbjct: 259 LHGKSIDGKVLYVGRAQKKI 278
Score = 36.2 bits (82), Expect = 0.089
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 52/222 (23%)
Query: 90 GTGEKKGPNRNRVFISNIPY--DMKWQAIKDLMREK---VGEVTYVELFKDAEGKSR-GC 143
G+GE + + ++ Y D+ +D++ +K G + + + +D +S G
Sbjct: 2 GSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGY 61
Query: 144 GVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGS 203
G V F+ + AL TMN ++G+P + + R+ S
Sbjct: 62 GYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRK------------------S 103
Query: 204 GLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRAD 263
G+ N IF+ NLD + + L +FS G +
Sbjct: 104 GVGN---------------------------IFIKNLDKSIDNRALFYLFSAFGNILSCK 136
Query: 264 IKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHV 305
+ D +G S+G V F+ A +AI NG L +R ++V
Sbjct: 137 VVCDDNG-SKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYV 177
Score = 35.0 bits (79), Expect = 0.20
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 15/152 (9%)
Query: 35 PAEAEKQQPQHSSSSNG---VKMENDESAKEEKSDLKEKST---------GSKKANRFHP 82
P E+ K S S G V+ E E+A++ DL KS KK R
Sbjct: 224 PTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAE 283
Query: 83 YSKD-KNSGTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSR 141
+ + EK P ++I N+ + + +K+ G ++ ++ + G+ +
Sbjct: 284 LRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEF-SSFGSISRAKVMMEV-GQGK 341
Query: 142 GCGVVEFKDEEFVKKALETMNKYDLSGRPLNI 173
G GVV F E KA++ MN + +PL++
Sbjct: 342 GFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
[Homo sapiens]
Length = 482
Score = 73.6 bits (179), Expect = 5e-13
Identities = 91/384 (23%), Positives = 159/384 (41%), Gaps = 37/384 (9%)
Query: 235 IFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI-SMF 293
+F+ + K ++ +FS G ++ I DG SRG VTF A AI +M
Sbjct: 110 LFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMH 169
Query: 294 NGQFL--FDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQL- 350
Q + PM VK D E+ R Q+ Q ISA+ +
Sbjct: 170 QAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQM---------------QQISAASVW 214
Query: 351 -NIGGVMGNLGPGGMGM--DGPGFGGMNRIGGGIGFGGLEAMN-----SMGGFGGVGRMG 402
N+ G + LGP + + G +N + GGL AM ++ +
Sbjct: 215 GNLAG-LNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNT 273
Query: 403 ELYRGAMTSSMERDFGRGDIGINRGFGDSFGRLGSAMIGGF---AGRIGSSNMGPVG--S 457
A+T+S G + S A +G AG N+G + +
Sbjct: 274 PSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMA 333
Query: 458 GISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRER 517
++GG+GS + ++ G G ++ ++ ++ + A L + + +G+ ++
Sbjct: 334 ALNGGLGS-SGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNL-LTQQSIGAAGSQK 391
Query: 518 IGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE--IKMENGKSKGCGTVRFDSPESA 575
G +G +F+ +LP + Q L + F G+V+ A+ I + SK G V +D+P SA
Sbjct: 392 EGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSA 451
Query: 576 EKACRIMNGIKISGREIDVRLDRN 599
+ A + MNG +I + + V+L R+
Sbjct: 452 QAAIQSMNGFQIGMKRLKVQLKRS 475
Score = 30.8 bits (68), Expect = 3.7
Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 9/125 (7%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L G + P +KN+ ++K
Sbjct: 53 QNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRK--- 109
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI I I+ +M G++ + + +G SRGC V F + A+
Sbjct: 110 ---LFIGMISKKCTENDIR-VMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAI 165
Query: 159 ETMNK 163
+ M++
Sbjct: 166 KAMHQ 170
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 229 GRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTVTFEQAIEAV 287
G G+ +F+ +L + G + L ++F G V A + DK S+ G V+++ + A
Sbjct: 393 GPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQ 452
Query: 288 QAISMFNG 295
AI NG
Sbjct: 453 AAIQSMNG 460
>gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2
[Homo sapiens]
Length = 483
Score = 73.6 bits (179), Expect = 5e-13
Identities = 90/387 (23%), Positives = 160/387 (41%), Gaps = 42/387 (10%)
Query: 235 IFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI-SMF 293
+F+ + K ++ +FS G ++ I DG SRG VTF A AI +M
Sbjct: 110 LFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMH 169
Query: 294 NGQFL--FDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQL- 350
Q + PM VK D E+ R Q+ Q ISA+ +
Sbjct: 170 QAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQM---------------QQISAASVW 214
Query: 351 -NIGGVMGNLGPGGMGM--DGPGFGGMNRIGGGIGFGGLEAMN-----SMGGFGGVGRMG 402
N+ G + LGP + + G +N + GGL AM ++ +
Sbjct: 215 GNLAG-LNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNT 273
Query: 403 ELYRGAMTSS------MERDFGRGDIGINRGFGDSFGRLGSAMIGGFAGRIGSSNMGPVG 456
A+T+S + G + + LG+ AG N+G +
Sbjct: 274 PSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQT--LAGATAGLNVGSLA 331
Query: 457 --SGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGM 514
+ ++GG+GS + ++ G G ++ ++ ++ + A L + + +G+
Sbjct: 332 GMAALNGGLGS-SGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNL-LTQQSIGAAG 389
Query: 515 RERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE--IKMENGKSKGCGTVRFDSP 572
++ G +G +F+ +LP + Q L + F G+V+ A+ I + SK G V +D+P
Sbjct: 390 SQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNP 449
Query: 573 ESAEKACRIMNGIKISGREIDVRLDRN 599
SA+ A + MNG +I + + V+L R+
Sbjct: 450 VSAQAAIQSMNGFQIGMKRLKVQLKRS 476
Score = 30.8 bits (68), Expect = 3.7
Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 9/125 (7%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L G + P +KN+ ++K
Sbjct: 53 QNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRK--- 109
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI I I+ +M G++ + + +G SRGC V F + A+
Sbjct: 110 ---LFIGMISKKCTENDIR-VMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAI 165
Query: 159 ETMNK 163
+ M++
Sbjct: 166 KAMHQ 170
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 229 GRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTVTFEQAIEAV 287
G G+ +F+ +L + G + L ++F G V A + DK S+ G V+++ + A
Sbjct: 394 GPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQ 453
Query: 288 QAISMFNG 295
AI NG
Sbjct: 454 AAIQSMNG 461
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 73.2 bits (178), Expect = 7e-13
Identities = 57/219 (26%), Positives = 101/219 (46%), Gaps = 34/219 (15%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
V+I N DM + +KDL K G V++ D GKS+G G V F+ E +KA++ M
Sbjct: 193 VYIKNFGEDMDDERLKDLFG-KFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 162 NKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPE 221
N +L+G+ + + + L+R + +
Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKR-------------------------KFEQMKQD 286
Query: 222 VISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFE 281
I+ Q G ++V NLD + ++L++ FS GT+ A + + G+S+G G V F
Sbjct: 287 RITRYQ----GVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMME-GGRSKGFGFVCFS 341
Query: 282 QAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSH 320
EA +A++ NG+ + +P++V + + EE ++H
Sbjct: 342 SPEEATKAVTEMNGRIVATKPLYVALAQRK---EERQAH 377
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/76 (38%), Positives = 47/76 (61%)
Query: 521 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACR 580
+G ++V+NL + ++L+++FS G + A++ ME G+SKG G V F SPE A KA
Sbjct: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351
Query: 581 IMNGIKISGREIDVRL 596
MNG ++ + + V L
Sbjct: 352 EMNGRIVATKPLYVAL 367
Score = 49.3 bits (116), Expect = 1e-05
Identities = 46/219 (21%), Positives = 89/219 (40%), Gaps = 51/219 (23%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
+FI N+ + +A+ D G + ++ D G S+G G V F+ +E ++A+E M
Sbjct: 101 IFIKNLDKSIDNKALYDTF-SAFGNILSCKVVCDENG-SKGYGFVHFETQEAAERAIEKM 158
Query: 162 NKYDLSGRPLNI-----KEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNP 216
N L+ R + + +++ + E RA + T
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAELGARAKEFTN-------------------------- 192
Query: 217 NIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMG 276
+++ N + ++LK++F G + D+ GKS+G G
Sbjct: 193 ------------------VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG 234
Query: 277 TVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHE 315
V+FE+ +A +A+ NG+ L + ++V K V +
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQ 273
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/71 (35%), Positives = 45/71 (63%), Gaps = 1/71 (1%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKM-ENGKSKGCGTVRFDSPESAEKACRIMN 583
++++N D+ ++LK+ F + G + ++ E+GKSKG G V F+ E A+KA MN
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 584 GIKISGREIDV 594
G +++G++I V
Sbjct: 253 GKELNGKQIYV 263
Score = 48.1 bits (113), Expect = 2e-05
Identities = 23/70 (32%), Positives = 43/70 (61%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
IF++NL + + L + FS G+++ ++ + SKG G V F++ E+AE+A MNG
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 585 IKISGREIDV 594
+ ++ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 35.4 bits (80), Expect = 0.15
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIM 582
++V +L D+T L EKFS G ++ + M +S G V F P AE+A M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 583 NGIKISGREIDV 594
N I G+ + +
Sbjct: 73 NFDVIKGKPVRI 84
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 73.2 bits (178), Expect = 7e-13
Identities = 107/413 (25%), Positives = 153/413 (37%), Gaps = 96/413 (23%)
Query: 90 GTGEKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGK-SRGCGVVEF 148
G K+ ++FI + ++ ++++ EK G +T + +D + K SRG G V +
Sbjct: 25 GHDPKEPEQLRKLFIGGLSFETTDDSLREHF-EKWGTLTDCVVMRDPQTKRSRGFGFVTY 83
Query: 149 KDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNL 208
E V A+ + + GR + K RA+ R PG H+
Sbjct: 84 SCVEEVDAAM-CARPHKVDGRVVEPK---------RAVSREDSVKPGAHLTV-------- 125
Query: 209 PPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK 268
IFV + L++ F G ++ ++ ED+
Sbjct: 126 ------------------------KKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDR 161
Query: 269 D-GKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQL 327
GK RG VTF+ + V I + + VK K++ +E +S Q
Sbjct: 162 QSGKKRGFAFVTFDDH-DTVDKIVVQKYHTINGHNCEVK---KALSKQEMQSAGS---QR 214
Query: 328 PRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGG---------------MGMDGPGFG 372
RG GG G +G GG N GG GN G GG G G G G
Sbjct: 215 GRG-GGSGNFMGRGG--------NFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDG 265
Query: 373 GMNRIGG-GIGFGGLEAMNSMGGFG----GVGRMGELYRGAMTSSMERDFGRGDIGINRG 427
G N GG G +GG +S GG+G G G G Y G G G G N G
Sbjct: 266 GYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGG----------GGGYDGYNEG 315
Query: 428 FGDSFGRLGSA----MIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMG 476
G G G ++G+ SN GP+ G GG S + GG G G
Sbjct: 316 GNFGGGNYGGGGNYNDFGNYSGQ-QQSNYGPMKGGSFGGRSSGSPYGGGYGSG 367
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 72.4 bits (176), Expect = 1e-12
Identities = 86/285 (30%), Positives = 111/285 (38%), Gaps = 46/285 (16%)
Query: 339 GPGGQPISASQLNIGGVMGNLGPGGMGMDG-----PGFGGMNRIGGGI-------GFGGL 386
G G QP +S G G G P +GG + G G+G
Sbjct: 99 GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158
Query: 387 EAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRGDIGINRGFGDSFGRLGSAMIGGFAGR 446
NS G GG G G Y G SSM G G G+G+ GG +G
Sbjct: 159 NQYNSSSGGGGGGGGGGNY-GQDQSSMSSGGGSGG-----GYGNQ-----DQSGGGGSGG 207
Query: 447 IGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSID-MDRGF 505
G + G G G SGG G GG G G +R S ++ G G G + DRG
Sbjct: 208 YGQQDRGGRGRGGSGGGG------GGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGG 261
Query: 506 LS---GPMGSGMR---ERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE------ 553
+ GP G R E+ S N IFV+ L ++T + + + F Q G + +
Sbjct: 262 FNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPM 321
Query: 554 ----IKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDV 594
E GK KG TV FD P SA+ A +G + SG I V
Sbjct: 322 INLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV 366
Score = 44.3 bits (103), Expect = 3e-04
Identities = 64/248 (25%), Positives = 86/248 (34%), Gaps = 41/248 (16%)
Query: 233 STIFVANLDFKVGWKKLKEVFSIAGTVKR--------ADIKEDKD-GKSRGMGTVTFEQA 283
+TIFV L V + + + F G +K ++ D++ GK +G TV+F+
Sbjct: 285 NTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDP 344
Query: 284 IEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQ 343
A AI F+G+ P+ V + G G G GG+
Sbjct: 345 PSAKAAIDWFDGKEFSGNPIKVSFATRRADFNR------------------GGGNGRGGR 386
Query: 344 PISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIG----FGGLEAMNSMGGFGGVG 399
GG MG G GG G G G GG GGG G G + N
Sbjct: 387 -------GRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFS 439
Query: 400 RMGELYRGAMTSSMERDFGRGDIGINRGFGDS-FGRLGSAMIGGFAGRIGSSN--MGPVG 456
E + G G + +GD G G GG+ GR G G G
Sbjct: 440 WRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRG 499
Query: 457 SGISGGMG 464
G GG G
Sbjct: 500 GGDRGGFG 507
Score = 36.6 bits (83), Expect = 0.068
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 17/136 (12%)
Query: 73 GSKKANRFHPYSKDKNSGT---GEKKGPNRNRVFISNIPYDMKWQAIKDLMRE------- 122
G F+ + ++ G+ E+ + N +F+ + ++ +++ D ++
Sbjct: 255 GGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTN 314
Query: 123 -KVGEVTYVELFKDAE-GKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGE 180
K G+ + L+ D E GK +G V F D K A++ + + SG P+ +
Sbjct: 315 KKTGQ-PMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKV----SFA 369
Query: 181 NARRALQRTGGSFPGG 196
R R GG+ GG
Sbjct: 370 TRRADFNRGGGNGRGG 385
>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
[Homo sapiens]
Length = 486
Score = 72.0 bits (175), Expect = 1e-12
Identities = 91/388 (23%), Positives = 159/388 (40%), Gaps = 41/388 (10%)
Query: 235 IFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAI-SMF 293
+F+ + K ++ +FS G ++ I DG SRG VTF A AI +M
Sbjct: 110 LFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMH 169
Query: 294 NGQFL--FDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQL- 350
Q + PM VK D E+ R Q+ Q ISA+ +
Sbjct: 170 QAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQM---------------QQISAASVW 214
Query: 351 -NIGGVMGNLGPGGMGM------DGPGFGGMNRIGGGIGFGGLEAMN-----SMGGFGGV 398
N+ G + LGP + + G +N + GGL AM ++
Sbjct: 215 GNLAG-LNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASA 273
Query: 399 GRMGELYRGAMTSSMERDFGRGDIGINRGFGDSFGRLGSAMIGGF---AGRIGSSNMGPV 455
+ A+T+S G + S A +G AG N+G +
Sbjct: 274 AQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSL 333
Query: 456 G--SGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSG 513
+ ++GG+GS + ++ G G ++ ++ ++ + A L + + +G+
Sbjct: 334 AGMAALNGGLGS-SGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNL-LTQQSIGAA 391
Query: 514 MRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE--IKMENGKSKGCGTVRFDS 571
++ G +G +F+ +LP + Q L + F G+V+ A+ I + SK G V +D+
Sbjct: 392 GSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDN 451
Query: 572 PESAEKACRIMNGIKISGREIDVRLDRN 599
P SA+ A + MNG +I + + V+L R+
Sbjct: 452 PVSAQAAIQSMNGFQIGMKRLKVQLKRS 479
Score = 30.8 bits (68), Expect = 3.7
Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 9/125 (7%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L G + P +KN+ ++K
Sbjct: 53 QNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRK--- 109
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI I I+ +M G++ + + +G SRGC V F + A+
Sbjct: 110 ---LFIGMISKKCTENDIR-VMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAI 165
Query: 159 ETMNK 163
+ M++
Sbjct: 166 KAMHQ 170
Score = 30.8 bits (68), Expect = 3.7
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 229 GRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTVTFEQAIEAV 287
G G+ +F+ +L + G + L ++F G V A + DK S+ G V+++ + A
Sbjct: 397 GPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQ 456
Query: 288 QAISMFNG 295
AI NG
Sbjct: 457 AAIQSMNG 464
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 71.2 bits (173), Expect = 2e-12
Identities = 65/269 (24%), Positives = 115/269 (42%), Gaps = 40/269 (14%)
Query: 44 QHSSSSNG-VKMENDESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRNRV 102
+H S G V E E+A++ + + +K H S+ + + +
Sbjct: 134 EHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNI 193
Query: 103 FISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMN 162
++ N+P D+ Q ++DL + G++ V++ +D G SR G V F+ E +KA+ MN
Sbjct: 194 YVKNLPVDVDEQGLQDLF-SQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 163 KYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEV 222
++SGR L A RA +R + N
Sbjct: 253 GKEVSGRLL---------YAGRAQKR------------------------VERQNELKRR 279
Query: 223 ISNLQAGRL----GSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTV 278
++ RL G ++V NLD + KL++ FS G + A + + G S+G G V
Sbjct: 280 FEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTE-GGHSKGFGFV 338
Query: 279 TFEQAIEAVQAISMFNGQFLFDRPMHVKM 307
F EA +A++ NG+ + +P++V +
Sbjct: 339 CFSSPEEATKAVTEMNGRIVGTKPLYVAL 367
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMEN-GKSKGCGTVRFDSPESAEKACRIMN 583
I+V+NLP D+ Q L++ FSQ G ++ ++ +N G S+ G V F+ E A+KA MN
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 584 GIKISGR 590
G ++SGR
Sbjct: 253 GKEVSGR 259
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/76 (38%), Positives = 43/76 (56%)
Query: 521 KGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACR 580
+G ++V+NL + KL+++FS G + A++ E G SKG G V F SPE A KA
Sbjct: 292 QGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVT 351
Query: 581 IMNGIKISGREIDVRL 596
MNG + + + V L
Sbjct: 352 EMNGRIVGTKPLYVAL 367
Score = 47.8 bits (112), Expect = 3e-05
Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 51/219 (23%)
Query: 102 VFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETM 161
+FI N+ + +A+ D G + ++ D G SRG G V F+ E ++A+ TM
Sbjct: 101 IFIKNLEDSIDNKALYDTF-STFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTM 158
Query: 162 NKYDLSGRPLNI-----KEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNP 216
N L+ R + + + + + E RAL+ T
Sbjct: 159 NGMLLNDRKVFVGHFKSRREREAELGARALEFTN-------------------------- 192
Query: 217 NIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMG 276
I+V NL V + L+++FS G + + D G SR G
Sbjct: 193 ------------------IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFG 234
Query: 277 TVTFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHE 315
V FE+ EA +A+ NG+ + R ++ K V +
Sbjct: 235 FVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQ 273
Score = 46.6 bits (109), Expect = 7e-05
Identities = 47/182 (25%), Positives = 70/182 (38%), Gaps = 47/182 (25%)
Query: 125 GEVTYVELFKD-AEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENAR 183
G + + + +D A +S G + F+ ++AL+TMN L G+P+ I R
Sbjct: 35 GPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLR 94
Query: 184 RALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANLDFK 243
+ SG+ N IF+ NL+
Sbjct: 95 K------------------SGVGN---------------------------IFIKNLEDS 109
Query: 244 VGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFDRPM 303
+ K L + FS G + + D+ G SRG G V FE A QAI+ NG L DR +
Sbjct: 110 IDNKALYDTFSTFGNILSCKVACDEHG-SRGFGFVHFETHEAAQQAINTMNGMLLNDRKV 168
Query: 304 HV 305
V
Sbjct: 169 FV 170
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/70 (30%), Positives = 43/70 (61%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNG 584
IF++NL + + L + FS G+++ ++ + S+G G V F++ E+A++A MNG
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNG 160
Query: 585 IKISGREIDV 594
+ ++ R++ V
Sbjct: 161 MLLNDRKVFV 170
Score = 33.9 bits (76), Expect = 0.44
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 525 IFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIM 582
++V +L D+T L EKFS G ++ + + +S G + F P AE+A M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72
Query: 583 NGIKISGREIDV 594
N + G+ I +
Sbjct: 73 NFEMLKGQPIRI 84
>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
[Homo sapiens]
Length = 508
Score = 70.9 bits (172), Expect = 3e-12
Identities = 120/533 (22%), Positives = 202/533 (37%), Gaps = 90/533 (16%)
Query: 93 EKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEG---KSRGCGVVEFK 149
++ P+ ++F+ IP + +K+L E G V + + +D +S+GC V F
Sbjct: 33 DQPDPDAIKMFVGQIPRSWSEKELKELF-EPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 91
Query: 150 DEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLP 209
K ALE N NIK + PG H P + +
Sbjct: 92 TR---KAALEAQNALH------NIK-----------------TLPGMHHP------IQMK 119
Query: 210 PSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD 269
P+ N + +F+ + K ++ +FS G ++ I D
Sbjct: 120 PADSEKSNAVED-----------RKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPD 168
Query: 270 GKSRGMGTVTFEQAIEAVQAI-SMFNGQFL--FDRPMHVKMDDKSVPHEEYRSHDG---K 323
G SRG VTF A AI +M Q + P+ VK D E+ R +
Sbjct: 169 GLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQ 228
Query: 324 TPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGF 383
QL G GLG G P + L NLG F G+ ++ G +
Sbjct: 229 MQQLNTATWGNLTGLG-GLTPQYLALLQQATSSSNLG---------AFSGIQQMAG-MNA 277
Query: 384 GGLEAMNSMGGFGGVGRMGELYR------------GAMTSSMERDFGRGDIGINRGFGDS 431
L+ + ++ + GA+TS + G S
Sbjct: 278 LQLQNLATLAAAAAAAQTSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTS 337
Query: 432 FGRLGSAMIGGFAGR-IGSSNMGPVG--SGISGGMGSMNSVTGGMGMGLDRMSSSFDRMG 488
G L G AG +G +N+ + + ++GG+G+ +T G +D ++ ++ +
Sbjct: 338 LGTLQ-----GLAGATVGLNNINALAGMAALNGGLGA-TGLTNGTAGTMDALTQAYSGIQ 391
Query: 489 PGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEKFSQCGH 548
A L GS ++ G +G +F+ +LP + Q + + F G+
Sbjct: 392 QYAAAALPTLYSQSLLQQQSAAGS---QKEGPEGANLFIYHLPQEFGDQDILQMFMPFGN 448
Query: 549 VMFAE--IKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRN 599
V+ A+ I + SK G V +D+P SA+ A + MNG +I + + V+L R+
Sbjct: 449 VISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRS 501
Score = 30.8 bits (68), Expect = 3.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 13/154 (8%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L T G + P +K++ ++K
Sbjct: 77 QNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK--- 133
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI + I+ +M G++ + + +G SRGC V F + A+
Sbjct: 134 ---LFIGMVSKKCNENDIR-VMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 189
Query: 159 ETMNK---YDLSGRPLNIK-EDPDGENARRALQR 188
+ M++ + P+ +K D + +R LQ+
Sbjct: 190 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ 223
>gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4
[Homo sapiens]
Length = 488
Score = 69.7 bits (169), Expect = 7e-12
Identities = 121/538 (22%), Positives = 199/538 (36%), Gaps = 96/538 (17%)
Query: 93 EKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEG---KSRGCGVVEFK 149
++ P+ ++F+ IP + +K+L E G V + + +D +S+GC V F
Sbjct: 9 DQPDPDAIKMFVGQIPRSWSEKELKELF-EPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 67
Query: 150 DEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLP 209
K ALE N NIK + PG H P + +
Sbjct: 68 TR---KAALEAQNALH------NIK-----------------TLPGMHHP------IQMK 95
Query: 210 PSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD 269
P+ N + +F+ + K ++ +FS G ++ I D
Sbjct: 96 PADSEKSNAVED-----------RKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPD 144
Query: 270 GKSRGMGTVTFEQAIEAVQAI-SMFNGQFL--FDRPMHVKMDDKSVPHEEYRSHDG---K 323
G SRG VTF A AI +M Q + P+ VK D E+ R +
Sbjct: 145 GLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQ 204
Query: 324 TPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGF 383
QL G GLG G P + L NLG F G+ ++ G +
Sbjct: 205 MQQLNTATWGNLTGLG-GLTPQYLALLQQATSSSNLG---------AFSGIQQMAG-MNA 253
Query: 384 GGLEAMNSMGGFGGVGRMGELYR------------GAMTSSMERDFGRGDIGINRGFGDS 431
L+ + ++ + GA+TS + G S
Sbjct: 254 LQLQNLATLAAAAAAAQTSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTS 313
Query: 432 FGRL--------GSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRMSSS 483
G L G I AG I S + ++GG+G+ +T G +D ++ +
Sbjct: 314 LGTLQGLAGATVGLNNINALAGTINSM------AALNGGLGA-TGLTNGTAGTMDALTQA 366
Query: 484 FDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEKF 543
+ + A L GS ++ G +G +F+ +LP + Q + + F
Sbjct: 367 YSGIQQYAAAALPTLYSQSLLQQQSAAGS---QKEGPEGANLFIYHLPQEFGDQDILQMF 423
Query: 544 SQCGHVMFAE--IKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRN 599
G+V+ A+ I + SK G V +D+P SA+ A + MNG +I + + V+L R+
Sbjct: 424 MPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRS 481
Score = 30.8 bits (68), Expect = 3.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 13/154 (8%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L T G + P +K++ ++K
Sbjct: 53 QNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK--- 109
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI + I+ +M G++ + + +G SRGC V F + A+
Sbjct: 110 ---LFIGMVSKKCNENDIR-VMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 165
Query: 159 ETMNK---YDLSGRPLNIK-EDPDGENARRALQR 188
+ M++ + P+ +K D + +R LQ+
Sbjct: 166 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ 199
>gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1
[Homo sapiens]
Length = 490
Score = 68.6 bits (166), Expect = 2e-11
Identities = 120/539 (22%), Positives = 202/539 (37%), Gaps = 96/539 (17%)
Query: 93 EKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEG---KSRGCGVVEFK 149
++ P+ ++F+ IP + +K+L E G V + + +D +S+GC V F
Sbjct: 9 DQPDPDAIKMFVGQIPRSWSEKELKELF-EPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 67
Query: 150 DEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLP 209
K ALE N NIK + PG H P + +
Sbjct: 68 TR---KAALEAQNALH------NIK-----------------TLPGMHHP------IQMK 95
Query: 210 PSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD 269
P+ N + +F+ + K ++ +FS G ++ I D
Sbjct: 96 PADSEKSNAVED-----------RKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPD 144
Query: 270 GKSRGMGTVTFEQAIEAVQAI-SMFNGQFL--FDRPMHVKMDDKSVPHEEYRSHDG---K 323
G SRG VTF A AI +M Q + P+ VK D E+ R +
Sbjct: 145 GLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQ 204
Query: 324 TPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGF 383
QL G GLG G P + L NLG F G+ ++ G +
Sbjct: 205 MQQLNTATWGNLTGLG-GLTPQYLALLQQATSSSNLG---------AFSGIQQMAG-MNA 253
Query: 384 GGLEAMNSMGGFGGVGRMGELYR------------GAMTSSMERDFGRGDIGINRGFGDS 431
L+ + ++ + GA+TS + G S
Sbjct: 254 LQLQNLATLAAAAAAAQTSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTS 313
Query: 432 FGRLGSAMIGGFAGR-IGSSNMGPVG--------SGISGGMGSMNSVTGGMGMGLDRMSS 482
G L G AG +G +N+ + + ++GG+G+ +T G +D ++
Sbjct: 314 LGTLQ-----GLAGATVGLNNINALAVAQMLSGMAALNGGLGA-TGLTNGTAGTMDALTQ 367
Query: 483 SFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEK 542
++ + A L GS ++ G +G +F+ +LP + Q + +
Sbjct: 368 AYSGIQQYAAAALPTLYSQSLLQQQSAAGS---QKEGPEGANLFIYHLPQEFGDQDILQM 424
Query: 543 FSQCGHVMFAE--IKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRN 599
F G+V+ A+ I + SK G V +D+P SA+ A + MNG +I + + V+L R+
Sbjct: 425 FMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRS 483
Score = 30.8 bits (68), Expect = 3.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 13/154 (8%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L T G + P +K++ ++K
Sbjct: 53 QNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK--- 109
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI + I+ +M G++ + + +G SRGC V F + A+
Sbjct: 110 ---LFIGMVSKKCNENDIR-VMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 165
Query: 159 ETMNK---YDLSGRPLNIK-EDPDGENARRALQR 188
+ M++ + P+ +K D + +R LQ+
Sbjct: 166 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ 199
>gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2
[Homo sapiens]
Length = 521
Score = 68.6 bits (166), Expect = 2e-11
Identities = 120/539 (22%), Positives = 202/539 (37%), Gaps = 96/539 (17%)
Query: 93 EKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEG---KSRGCGVVEFK 149
++ P+ ++F+ IP + +K+L E G V + + +D +S+GC V F
Sbjct: 40 DQPDPDAIKMFVGQIPRSWSEKELKELF-EPYGAVYQINVLRDRSQNPPQSKGCCFVTFY 98
Query: 150 DEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLP 209
K ALE N NIK + PG H P + +
Sbjct: 99 TR---KAALEAQNALH------NIK-----------------TLPGMHHP------IQMK 126
Query: 210 PSILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD 269
P+ N + +F+ + K ++ +FS G ++ I D
Sbjct: 127 PADSEKSNAVED-----------RKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPD 175
Query: 270 GKSRGMGTVTFEQAIEAVQAI-SMFNGQFL--FDRPMHVKMDDKSVPHEEYRSHDG---K 323
G SRG VTF A AI +M Q + P+ VK D E+ R +
Sbjct: 176 GLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQQLAQQ 235
Query: 324 TPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGF 383
QL G GLG G P + L NLG F G+ ++ G +
Sbjct: 236 MQQLNTATWGNLTGLG-GLTPQYLALLQQATSSSNLG---------AFSGIQQMAG-MNA 284
Query: 384 GGLEAMNSMGGFGGVGRMGELYR------------GAMTSSMERDFGRGDIGINRGFGDS 431
L+ + ++ + GA+TS + G S
Sbjct: 285 LQLQNLATLAAAAAAAQTSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNSLTS 344
Query: 432 FGRLGSAMIGGFAGR-IGSSNMGPVG--------SGISGGMGSMNSVTGGMGMGLDRMSS 482
G L G AG +G +N+ + + ++GG+G+ +T G +D ++
Sbjct: 345 LGTLQ-----GLAGATVGLNNINALAVAQMLSGMAALNGGLGA-TGLTNGTAGTMDALTQ 398
Query: 483 SFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLKEK 542
++ + A L GS ++ G +G +F+ +LP + Q + +
Sbjct: 399 AYSGIQQYAAAALPTLYSQSLLQQQSAAGS---QKEGPEGANLFIYHLPQEFGDQDILQM 455
Query: 543 FSQCGHVMFAE--IKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRN 599
F G+V+ A+ I + SK G V +D+P SA+ A + MNG +I + + V+L R+
Sbjct: 456 FMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRS 514
Score = 30.8 bits (68), Expect = 3.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 13/154 (8%)
Query: 41 QQPQHSSSSNGVKMENDESAKEEKSDLKEKST--GSKKANRFHPYSKDKNSGTGEKKGPN 98
Q P S V ++A E ++ L T G + P +K++ ++K
Sbjct: 84 QNPPQSKGCCFVTFYTRKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRK--- 140
Query: 99 RNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
+FI + I+ +M G++ + + +G SRGC V F + A+
Sbjct: 141 ---LFIGMVSKKCNENDIR-VMFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAI 196
Query: 159 ETMNK---YDLSGRPLNIK-EDPDGENARRALQR 188
+ M++ + P+ +K D + +R LQ+
Sbjct: 197 KAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ 230
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 68.2 bits (165), Expect = 2e-11
Identities = 89/295 (30%), Positives = 119/295 (40%), Gaps = 47/295 (15%)
Query: 181 NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGS-----TI 235
N + R G +V + + + P ++ N +S + R G+ +
Sbjct: 41 NPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKL 100
Query: 236 FVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTVTFEQAIEAVQAISMFN 294
FV L V L E FS GTV++A+I DK GK RG G V F+ +A ++
Sbjct: 101 FVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNH-DAADKAAVVK 159
Query: 295 GQFLFDRPMHVKMDDKSVPHEE-YRSHDGKTPQLPRG-LGGIGMGLGPGGQPISASQLNI 352
+ + VK K+VP E+ Y G + RG GG G G GG+ + L+
Sbjct: 160 FHPIQGHRVEVK---KAVPKEDIYSGGGGGGSRSSRGGRGGRGRG---GGR--DQNGLSK 211
Query: 353 GGVMGNLGPGGMGMDGPGFGGMNRIGGGIG---FGGLEAMNSMGGFGGVGRMGELYRGAM 409
GG G GG G G G GG N GGG G +GG + N GGFG + Y G M
Sbjct: 212 GGGGGYNSYGGYG--GGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSY-GPM 268
Query: 410 TSSMERDFGRGDIGINRGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMG 464
S G G G S+G G SN GP G GG G
Sbjct: 269 KSG----------GGGGGGGSSWG--------------GRSNSGPYRGGYGGGGG 299
Score = 38.9 bits (89), Expect = 0.014
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 520 SKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEK 577
+K ++FV L D+ L E FSQ G V AEI ++GK +G G V F + ++A+K
Sbjct: 95 AKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADK 154
Query: 578 ACRIMNGIKISGREIDVR 595
A ++ I G ++V+
Sbjct: 155 AA-VVKFHPIQGHRVEVK 171
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 65.9 bits (159), Expect = 1e-10
Identities = 99/393 (25%), Positives = 144/393 (36%), Gaps = 79/393 (20%)
Query: 93 EKKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKD-AEGKSRGCGVVEFKDE 151
E++ ++FI + ++ +++++ E+ G++T + +D A +SRG G V F
Sbjct: 2 EREKEQFRKLFIGGLSFETTEESLRNYY-EQWGKLTDCVVMRDPASKRSRGFGFVTFSSM 60
Query: 152 EFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPS 211
V A+ + + GR + K RA+ R PG HV
Sbjct: 61 AEVDAAMAA-RPHSIDGRVVEPK---------RAVAREESGKPGAHVTV----------- 99
Query: 212 ILNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-G 270
+FV + L++ F G + +I D+ G
Sbjct: 100 ---------------------KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSG 138
Query: 271 KSRGMGTVTFEQAIEA----VQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQ 326
K RG G VTF+ +Q NG R + + + V + RS G
Sbjct: 139 KKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEV--QSSRSGRGGNFG 196
Query: 327 LPRGLGGIG-MGLGPGGQPISASQLNIGGVMGNLGPG---GMGMDGPGFG-GMNRIGGGI 381
GG G G GPG N G G G G G +G G G G GG
Sbjct: 197 FGDSRGGGGNFGPGPGS--------NFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSP 248
Query: 382 GFGGLEAMNSMGGFGG----VGRMGELYRGAMTSSMERDFGRG---DIGINRGFGDSFGR 434
G+GG GG+GG G G Y G + ++G G D G ++G
Sbjct: 249 GYGG-----GRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGP 303
Query: 435 LGSAMIGG---FAGRIGSSNMGPVGSGISGGMG 464
+ S GG G G N GP GSG SGG G
Sbjct: 304 MKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYG 336
Score = 32.0 bits (71), Expect = 1.7
Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 9/120 (7%)
Query: 483 SFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKG-----NQIFVRNLPFDLTWQ 537
+F M A+ R +D G + P + RE G G ++FV + D
Sbjct: 56 TFSSMAEVDAAMAARPHSID-GRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEH 114
Query: 538 KLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVR 595
L++ F + G + EI ++GK +G G V FD + +K + I+G +VR
Sbjct: 115 HLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV-LQKYHTINGHNAEVR 173
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 65.5 bits (158), Expect = 1e-10
Identities = 101/349 (28%), Positives = 123/349 (35%), Gaps = 74/349 (21%)
Query: 233 STIFVANLDFKVGWKKLKEVFSIAGTVKR--------ADIKEDKD-GKSRGMGTVTFEQA 283
+TIFV L V ++ E F G +K ++ DKD GK +G TV+F+
Sbjct: 231 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 290
Query: 284 IEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQ 343
A AI F+G+ + V + P G + G G G G GG
Sbjct: 291 PSAKAAIDWFDGKEFHGNIIKVSFATRR-PEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 349
Query: 344 P--------------------ISASQLN------------------IGGVMGNLGPGGMG 365
P S +Q N GG G G GG G
Sbjct: 350 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 409
Query: 366 MDGPGFGGMNRIGGGIG-----FGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG 420
D G+GG +R GGG G GG S GG+GG R G Y G D G G
Sbjct: 410 GDRGGYGG-DRSGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRG-G 466
Query: 421 DIGINR--GFGDSFGRLGSAMIGGFAGRIG--SSNMGPVG------SGISGGMGSMNS-- 468
G +R G+G G G GG+ G G + G G G GG G S
Sbjct: 467 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 526
Query: 469 -----VTGGMGMGLDRMSS-SFDRMGPGIGAILERSIDMDRGFLSGPMG 511
GG G G DR DR G G G DRG G MG
Sbjct: 527 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 575
Score = 44.7 bits (104), Expect = 2e-04
Identities = 49/142 (34%), Positives = 55/142 (38%), Gaps = 9/142 (6%)
Query: 330 GLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAM 389
G GG G G GG + GG G GG G D G+GG GGG G
Sbjct: 442 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR--GGGYGGDRGGYG 499
Query: 390 NSMGGFGGV--GRMGELYRGAMTSSMERDFGRGDIGINRGFGD--SFGRLGSAMIGGFAG 445
GG+GG G G+ RG R GD G G+G S G G GG+ G
Sbjct: 500 GDRGGYGGDRGGYGGD--RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557
Query: 446 RIGSSNMGPVGSGISGGMGSMN 467
G G G G G MG N
Sbjct: 558 DRGGGYGGDRG-GYGGKMGGRN 578
Score = 38.1 bits (87), Expect = 0.023
Identities = 41/142 (28%), Positives = 52/142 (36%), Gaps = 23/142 (16%)
Query: 471 GGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLS--------GPMGSGMRERIGSKG 522
G G G R D GP G S DRG GP E S
Sbjct: 176 GSQGGGRGRGGYDKDGRGPMTG-----SSGGDRGGFKNFGGHRDYGPRTDADSESDNSDN 230
Query: 523 NQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE----------IKMENGKSKGCGTVRFDSP 572
N IFV+ L ++ ++ E F Q G + + + GK KG TV FD P
Sbjct: 231 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 290
Query: 573 ESAEKACRIMNGIKISGREIDV 594
SA+ A +G + G I V
Sbjct: 291 PSAKAAIDWFDGKEFHGNIIKV 312
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 65.5 bits (158), Expect = 1e-10
Identities = 101/349 (28%), Positives = 123/349 (35%), Gaps = 74/349 (21%)
Query: 233 STIFVANLDFKVGWKKLKEVFSIAGTVKR--------ADIKEDKD-GKSRGMGTVTFEQA 283
+TIFV L V ++ E F G +K ++ DKD GK +G TV+F+
Sbjct: 234 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293
Query: 284 IEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQ 343
A AI F+G+ + V + P G + G G G G GG
Sbjct: 294 PSAKAAIDWFDGKEFHGNIIKVSFATRR-PEFMRGGGSGGGRRGRGGYRGRGGFQGRGGD 352
Query: 344 P--------------------ISASQLN------------------IGGVMGNLGPGGMG 365
P S +Q N GG G G GG G
Sbjct: 353 PKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRG 412
Query: 366 MDGPGFGGMNRIGGGIG-----FGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG 420
D G+GG +R GGG G GG S GG+GG R G Y G D G G
Sbjct: 413 GDRGGYGG-DRSGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGGDRGGGYGGDRG-G 469
Query: 421 DIGINR--GFGDSFGRLGSAMIGGFAGRIG--SSNMGPVG------SGISGGMGSMNS-- 468
G +R G+G G G GG+ G G + G G G GG G S
Sbjct: 470 GYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRG 529
Query: 469 -----VTGGMGMGLDRMSS-SFDRMGPGIGAILERSIDMDRGFLSGPMG 511
GG G G DR DR G G G DRG G MG
Sbjct: 530 GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMG 578
Score = 44.7 bits (104), Expect = 2e-04
Identities = 49/142 (34%), Positives = 55/142 (38%), Gaps = 9/142 (6%)
Query: 330 GLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAM 389
G GG G G GG + GG G GG G D G+GG GGG G
Sbjct: 445 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR--GGGYGGDRGGYG 502
Query: 390 NSMGGFGGV--GRMGELYRGAMTSSMERDFGRGDIGINRGFGD--SFGRLGSAMIGGFAG 445
GG+GG G G+ RG R GD G G+G S G G GG+ G
Sbjct: 503 GDRGGYGGDRGGYGGD--RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560
Query: 446 RIGSSNMGPVGSGISGGMGSMN 467
G G G G G MG N
Sbjct: 561 DRGGGYGGDRG-GYGGKMGGRN 581
Score = 38.1 bits (87), Expect = 0.023
Identities = 41/142 (28%), Positives = 52/142 (36%), Gaps = 23/142 (16%)
Query: 471 GGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLS--------GPMGSGMRERIGSKG 522
G G G R D GP G S DRG GP E S
Sbjct: 179 GSQGGGRGRGGYDKDGRGPMTG-----SSGGDRGGFKNFGGHRDYGPRTDADSESDNSDN 233
Query: 523 NQIFVRNLPFDLTWQKLKEKFSQCGHVMFAE----------IKMENGKSKGCGTVRFDSP 572
N IFV+ L ++ ++ E F Q G + + + GK KG TV FD P
Sbjct: 234 NTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATVSFDDP 293
Query: 573 ESAEKACRIMNGIKISGREIDV 594
SA+ A +G + G I V
Sbjct: 294 PSAKAAIDWFDGKEFHGNIIKV 315
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 65.1 bits (157), Expect = 2e-10
Identities = 98/385 (25%), Positives = 141/385 (36%), Gaps = 79/385 (20%)
Query: 101 RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKD-AEGKSRGCGVVEFKDEEFVKKALE 159
++FI + ++ +++++ E+ G++T + +D A +SRG G V F V A+
Sbjct: 22 KLFIGGLSFETTEESLRNYY-EQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMA 80
Query: 160 TMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIP 219
+ + GR + K RA+ R PG HV
Sbjct: 81 A-RPHSIDGRVVEPK---------RAVAREESGKPGAHVTV------------------- 111
Query: 220 PEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKD-GKSRGMGTV 278
+FV + L++ F G + +I D+ GK RG G V
Sbjct: 112 -------------KKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFV 158
Query: 279 TFEQAIEA----VQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGI 334
TF+ +Q NG R + + + V + RS G GG
Sbjct: 159 TFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEV--QSSRSGRGGNFGFGDSRGGG 216
Query: 335 G-MGLGPGGQPISASQLNIGGVMGNLGPG---GMGMDGPGFG-GMNRIGGGIGFGGLEAM 389
G G GPG N G G G G G +G G G G GG G+GG
Sbjct: 217 GNFGPGPGS--------NFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGG---- 264
Query: 390 NSMGGFGG----VGRMGELYRGAMTSSMERDFGRG---DIGINRGFGDSFGRLGSAMIGG 442
GG+GG G G Y G + ++G G D G ++G + S GG
Sbjct: 265 -GRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGG 323
Query: 443 ---FAGRIGSSNMGPVGSGISGGMG 464
G G N GP GSG SGG G
Sbjct: 324 SRNMGGPYGGGNYGPGGSGGSGGYG 348
Score = 32.0 bits (71), Expect = 1.7
Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 9/120 (7%)
Query: 483 SFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKG-----NQIFVRNLPFDLTWQ 537
+F M A+ R +D G + P + RE G G ++FV + D
Sbjct: 68 TFSSMAEVDAAMAARPHSID-GRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEH 126
Query: 538 KLKEKFSQCGHVMFAEI--KMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVR 595
L++ F + G + EI ++GK +G G V FD + +K + I+G +VR
Sbjct: 127 HLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIV-LQKYHTINGHNAEVR 185
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 63.9 bits (154), Expect = 4e-10
Identities = 97/386 (25%), Positives = 139/386 (36%), Gaps = 69/386 (17%)
Query: 94 KKGPNRNRVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGK-SRGCGVVEFKDEE 152
K+ ++FI + ++ ++++ E+ G +T + +D K SRG G V + E
Sbjct: 8 KEPEQLRKLFIGGLSFETTDESLRSHF-EQWGTLTDCVVMRDPNTKRSRGFGFVTYATVE 66
Query: 153 FVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSI 212
V A+ + + GR + K RA+ R PG H+
Sbjct: 67 EVDAAMNA-RPHKVDGRVVEPK---------RAVSREDSQRPGAHLTV------------ 104
Query: 213 LNNPNIPPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDK-DGK 271
IFV + L++ F G ++ +I D+ GK
Sbjct: 105 --------------------KKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGK 144
Query: 272 SRGMGTVTFEQAIEA----VQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQL 327
RG VTF+ +Q NG R K + S + R G
Sbjct: 145 KRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQ-RGRSGS---- 199
Query: 328 PRGLGGIGMGLGPGGQPISASQLNI---GGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFG 384
G G G G G GG N GG G+ G GG G G G+ G GG G G
Sbjct: 200 --GNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGN-DGGYGGG 256
Query: 385 GLEAMNSMGGFG----GVGRMGELYRGAMTSSMERDFGRGDIGINRGFGDSFGRLGSAM- 439
G G+G G G G Y G+ + + G G G G G +FG GS
Sbjct: 257 GPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGG--GFGGGSGSNFGGGGSYND 314
Query: 440 IGGFAGRIGSSNMGPVGSGISGGMGS 465
G + + SSN GP+ G GG S
Sbjct: 315 FGNYNNQ--SSNFGPMKGGNFGGRSS 338
Score = 37.0 bits (84), Expect = 0.052
Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 12/124 (9%)
Query: 410 TSSMERDFGRGDIGINRGFG----DSFGRLGS-AMIGGFAGRIGSSNMGPVGSGIS---- 460
+SS G G+ G RG G D+FGR G+ + GGF G G G G G +
Sbjct: 190 SSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGN 249
Query: 461 -GGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIG 519
GG G G G + G G G S D G G G G
Sbjct: 250 DGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGG--SGSYDSYNNGGGGGFGGGSGSNFG 307
Query: 520 SKGN 523
G+
Sbjct: 308 GGGS 311
Score = 32.0 bits (71), Expect = 1.7
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 524 QIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME--NGKSKGCGTVRFDSPESAEKACRI 581
+IFV + D L++ F Q G + EI + +GK +G V FD +S +K I
Sbjct: 106 KIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV-I 164
Query: 582 MNGIKISGREIDVR 595
++G +VR
Sbjct: 165 QKYHTVNGHNCEVR 178
>gi|238776833 THO complex 4 [Homo sapiens]
Length = 264
Score = 63.5 bits (153), Expect = 5e-10
Identities = 34/110 (30%), Positives = 59/110 (53%)
Query: 232 GSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAIS 291
G + V+NLDF V ++E+F+ GT+K+A + D+ G+S G V FE+ +A++A+
Sbjct: 112 GGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMK 171
Query: 292 MFNGQFLFDRPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPG 341
+NG L RPM++++ + + + + R G G G G G
Sbjct: 172 QYNGVPLDGRPMNIQLVTSQIDAQRRPAQSVNRGGMTRNRGAGGFGGGGG 221
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 7/159 (4%)
Query: 445 GRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRMSSSFDRMGPGIG-----AILERSI 499
GR G G GS G G+ + G G R + R G G A R
Sbjct: 29 GRGGGRGRGRAGSQGGRGGGAQAAARVNRGGGPIRNRPAIARGAAGGGGRNRPAPYSRPK 88
Query: 500 DMDRGFLSGPMGSGMRERIGSK-GNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKME- 557
+ + SG G + G ++ V NL F ++ ++E F++ G + A + +
Sbjct: 89 QLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDR 148
Query: 558 NGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRL 596
+G+S G V F+ A KA + NG+ + GR ++++L
Sbjct: 149 SGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQL 187
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 71 STGSKKANRFHPYSKDK-----------NSGTGEKKGPNRN-RVFISNIPYDMKWQAIKD 118
+ G NR PYS+ K +SG G G ++ +SN+ + + I++
Sbjct: 72 AAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQE 131
Query: 119 LMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIK 174
L E G + + D G+S G V F+ + KA++ N L GRP+NI+
Sbjct: 132 LFAE-FGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQ 186
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 61.2 bits (147), Expect = 3e-09
Identities = 53/150 (35%), Positives = 62/150 (41%), Gaps = 16/150 (10%)
Query: 327 LPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGL 386
L R GG G GLG GG I +S G G GG G+GG + G G GG
Sbjct: 11 LSRSGGGGGGGLGSGGS-IRSSYSRFSSSGGG-GGGGRFSSSSGYGGGSSRVCGRGGGGS 68
Query: 387 EAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRGDIGINRGFGDSFGRLGSAMIGGFAGR 446
+ GG GG G SS+ FG G +RGFG + G G + GGF G
Sbjct: 69 FGYSYGGGSGG---------GFSASSLGGGFGGG----SRGFGGASGG-GYSSSGGFGGG 114
Query: 447 IGSSNMGPVGSGISGGMGSMNSVTGGMGMG 476
G + G G G G G GG G G
Sbjct: 115 FGGGSGGGFGGGYGSGFGGFGGFGGGAGGG 144
Score = 50.4 bits (119), Expect = 5e-06
Identities = 57/165 (34%), Positives = 68/165 (41%), Gaps = 17/165 (10%)
Query: 330 GLGGIGMGLGPGGQPISASQLNIGGVMGNLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAM 389
G G IG+G G GG S + + GG G+ G GG G G G G +R G G +GG
Sbjct: 469 GAGKIGLG-GRGGSGGSYGRGSRGGSGGSYGGGGSG-GGYGGGSGSRGGSGGSYGG---- 522
Query: 390 NSMGGFGGVGRMGELYRGAMTSSMERDFGRGDIGINRG-FGDSFGRLGSAMIGGFAGRIG 448
G G G G Y G G G G + G +G G G GG+ G G
Sbjct: 523 ----GSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS-GGGSGGGYGGGSG 577
Query: 449 SSNMGPVGSGISGGMGS-MNSVTGGMGMGLDRMSSSFDRMGPGIG 492
S GSG S G GS +GG G + S S G G G
Sbjct: 578 SRG----GSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618
Score = 46.2 bits (108), Expect = 9e-05
Identities = 44/136 (32%), Positives = 47/136 (34%), Gaps = 1/136 (0%)
Query: 358 NLGPGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDF 417
NL GG G +GG G GG S GG GG G G S R
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515
Query: 418 GRGDIGINRGF-GDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMG 476
G G G G S G G GG +G G + G G GG GS GG G G
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG 575
Query: 477 LDRMSSSFDRMGPGIG 492
S G G G
Sbjct: 576 SGSRGGSGGSHGGGSG 591
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 87 KNSGTGEKKGPNRN--RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCG 144
+ SG + P R R+ + N+ WQ +KD MR+ GEVTY + K + + G
Sbjct: 89 RRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQ-AGEVTYADAHKGRKNE----G 143
Query: 145 VVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGENARRALQRT 189
V+EF +K+ALE ++ +++GR + + ED G RR+ R+
Sbjct: 144 VIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRS 188
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 502 DRGFLSGPMGSGMRERIGSKGN-------QIFVRNLPFDLTWQKLKEKFSQCGHVMFAEI 554
D + SG G G R K ++ V NL +WQ LK+ Q G V +A+
Sbjct: 76 DGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYAD- 134
Query: 555 KMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDR 598
G+ K G + F S ++A ++G +++GR+I + D+
Sbjct: 135 -AHKGR-KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDK 176
Score = 32.7 bits (73), Expect = 0.98
Identities = 46/208 (22%), Positives = 77/208 (37%), Gaps = 35/208 (16%)
Query: 101 RVFISNIPYDMKWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALET 160
RV+I + Y + + ++ + G++ V+L G G VEF D A+
Sbjct: 3 RVYIGRLSYQARERDVERFFKG-YGKILEVDL-------KNGYGFVEFDDLRDADDAVYE 54
Query: 161 MNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPP 220
+N DL G + + E+AR R GS+ G G G P
Sbjct: 55 LNGKDLCGERVIV------EHARGP--RRDGSYGSGR---SGYGYRRSGRDKYGPPT--- 100
Query: 221 EVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTF 280
R + V NL + W+ LK+ AG V AD + + + G + F
Sbjct: 101 ---------RTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGR----KNEGVIEF 147
Query: 281 EQAIEAVQAISMFNGQFLFDRPMHVKMD 308
+ +A+ +G + R + + D
Sbjct: 148 VSYSDMKRALEKLDGTEVNGRKIRLVED 175
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 57.8 bits (138), Expect = 3e-08
Identities = 39/130 (30%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 58 ESAKEEKSDLKEKSTGSKKANRFHPYSKDKNSGTGEKKGPNRN--RVFISNIPYDMKWQA 115
E A+ + D S GS+ YS + SG + P R R+ + N+ WQ
Sbjct: 68 EHARGPRRDRDGYSYGSRSGGG--GYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCSWQD 125
Query: 116 IKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKE 175
+KD MR+ GEVTY + K+ + GV+EF+ +K+AL+ ++ +++GR + + E
Sbjct: 126 LKDFMRQ-AGEVTYADAHKERTNE----GVIEFRSYSDMKRALDKLDGTEINGRNIRLIE 180
Query: 176 DPDGENARRA 185
D + RR+
Sbjct: 181 DKPRTSHRRS 190
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/224 (21%), Positives = 83/224 (37%), Gaps = 35/224 (15%)
Query: 101 RVFISNIPYDMKWQAIKDLMR--EKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKAL 158
RV+I + Y+++ KD+ R G + V+L G G VEF+D A+
Sbjct: 3 RVYIGRLSYNVRE---KDIQRFFSGYGRLLEVDL-------KNGYGFVEFEDSRDADDAV 52
Query: 159 ETMNKYDLSGRPLNIKEDPDGENARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNI 218
+N +L G + ++ R S GG+ SG P +
Sbjct: 53 YELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPV------ 106
Query: 219 PPEVISNLQAGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTV 278
R + V NL + W+ LK+ AG V AD +++ + G +
Sbjct: 107 -----------RTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNE----GVI 151
Query: 279 TFEQAIEAVQAISMFNGQFLFDRPMHVKMDDKSVPHEEYRSHDG 322
F + +A+ +G + R + + D H RS+ G
Sbjct: 152 EFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHR--RSYSG 193
Score = 38.1 bits (87), Expect = 0.023
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 524 QIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMN 583
++ V NL +WQ LK+ Q G V +A+ E G + F S ++A ++
Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNE---GVIEFRSYSDMKRALDKLD 167
Query: 584 GIKISGREIDVRLDR 598
G +I+GR I + D+
Sbjct: 168 GTEINGRNIRLIEDK 182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,154,166
Number of Sequences: 37866
Number of extensions: 1439758
Number of successful extensions: 10061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 215
Number of HSP's successfully gapped in prelim test: 357
Number of HSP's that attempted gapping in prelim test: 6565
Number of HSP's gapped (non-prelim): 2531
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.