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Search of human proteins with 33356163
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33356163 eukaryotic translation initiation factor 1A, Y
chromosome [Homo sapiens]
(144 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33356163 eukaryotic translation initiation factor 1A, Y chrom... 298 1e-81
gi|4503499 X-linked eukaryotic translation initiation factor 1A ... 297 2e-81
gi|31377656 eukaryotic translation initiation factor 1A domain c... 41 3e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 30 0.70
gi|55956788 nucleolin [Homo sapiens] 29 1.2
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 29 1.6
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 28 2.0
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens] 28 2.0
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 28 2.0
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 28 2.0
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 28 2.0
gi|62821787 COBL-like 1 [Homo sapiens] 28 2.0
gi|7662072 zinc finger and BTB domain containing 39 [Homo sapiens] 28 2.0
gi|156071452 nardilysin isoform b [Homo sapiens] 28 2.7
gi|156071450 nardilysin isoform a [Homo sapiens] 28 2.7
gi|19924161 RPB5-mediating protein isoform b [Homo sapiens] 28 3.5
gi|19924159 RPB5-mediating protein isoform a [Homo sapiens] 28 3.5
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 27 4.5
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 27 4.5
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 27 4.5
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 27 5.9
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 27 5.9
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 27 5.9
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 27 5.9
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 27 5.9
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 27 5.9
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 27 5.9
gi|189217919 protein associated with topoisomerase II homolog 1 ... 27 5.9
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso... 27 7.7
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso... 27 7.7
>gi|33356163 eukaryotic translation initiation factor 1A, Y
chromosome [Homo sapiens]
Length = 144
Score = 298 bits (762), Expect = 1e-81
Identities = 144/144 (100%), Positives = 144/144 (100%)
Query: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCH 60
MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCH
Sbjct: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCH 60
Query: 61 IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT 120
IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT
Sbjct: 61 IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT 120
Query: 121 FGPGDDDEIQFDDIGDDDEDIDDI 144
FGPGDDDEIQFDDIGDDDEDIDDI
Sbjct: 121 FGPGDDDEIQFDDIGDDDEDIDDI 144
>gi|4503499 X-linked eukaryotic translation initiation factor 1A
[Homo sapiens]
Length = 144
Score = 297 bits (760), Expect = 2e-81
Identities = 143/144 (99%), Positives = 144/144 (100%)
Query: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCH 60
MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEA+CFDGVKRLCH
Sbjct: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCH 60
Query: 61 IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT 120
IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT
Sbjct: 61 IRGKLRKKVWINTSDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT 120
Query: 121 FGPGDDDEIQFDDIGDDDEDIDDI 144
FGPGDDDEIQFDDIGDDDEDIDDI
Sbjct: 121 FGPGDDDEIQFDDIGDDDEDIDDI 144
>gi|31377656 eukaryotic translation initiation factor 1A domain
containing [Homo sapiens]
Length = 165
Score = 41.2 bits (95), Expect = 3e-04
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Query: 19 NESEKRELVFKE---------DGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKLRKKV 69
+++ KR+ V KE D Q+ +V++ GN E G + L + K RK +
Sbjct: 2 SQATKRKHVVKEVLGEHIVPSDQQQIVRVLRTPGNNLHEVETAQGQRFLVSMPSKYRKNI 61
Query: 70 WINTSDIILVG-LRDYQDNKADVILKYNADEARSLKAYGELPE 111
WI D ++V + + + KA++ D RSL+ G PE
Sbjct: 62 WIKRGDFLIVDPIEEGEKVKAEISFVLCKDHVRSLQKEGFWPE 104
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 30.0 bits (66), Expect = 0.70
Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 6/48 (12%)
Query: 3 KNKGKGGKNRRRGKNENESEKR------ELVFKEDGQEYAQVIKMLGN 44
+ +G+G +NRR + E E E + E ++DG+EY +V K+ G+
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGS 1094
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 29.3 bits (64), Expect = 1.2
Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 100 ARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
A+ KA +P AK N + +DDE + DD +DDED DD
Sbjct: 216 AKGKKAAKVVPVKAK-NVAEDEDEEEDDEDEDDDDDEDDEDDDD 258
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 28.9 bits (63), Expect = 1.6
Identities = 18/63 (28%), Positives = 28/63 (44%)
Query: 81 LRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDED 140
L Y K I + + + + + E E + E + G +DDE DD DDD+D
Sbjct: 216 LNMYTRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDD 275
Query: 141 IDD 143
D+
Sbjct: 276 DDE 278
Score = 27.3 bits (59), Expect = 4.5
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 4/37 (10%)
Query: 107 GELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
GE EH E D D+D+ DD DDD+D DD
Sbjct: 248 GEDQEH----EDDGEDEDDEDDDDDDDDDDDDDDEDD 280
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 28.5 bits (62), Expect = 2.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 125 DDDEIQFDDIGDDDEDIDD 143
DDD+ + DD DDD+D DD
Sbjct: 165 DDDDEEDDDEDDDDDDFDD 183
>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
Length = 265
Score = 28.5 bits (62), Expect = 2.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 125 DDDEIQFDDIGDDDEDIDD 143
DDD+ + DD DDD+D DD
Sbjct: 165 DDDDEEDDDEDDDDDDFDD 183
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 28.5 bits (62), Expect = 2.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 125 DDDEIQFDDIGDDDEDIDD 143
DDD+ + DD DDD+D DD
Sbjct: 165 DDDDEEDDDEDDDDDDFDD 183
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 28.5 bits (62), Expect = 2.0
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Query: 108 ELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDI 141
ELPE ++ D DDD+ + DD DDDED+
Sbjct: 1683 ELPEEEAEDDEDEDDDEDDDD-EDDDEDDDDEDL 1715
Score = 28.1 bits (61), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 111 EHAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
E ++ E + D+D+ + DD DDDED DD
Sbjct: 1680 EELELPEEEAEDDEDEDDDEDDDDEDDDEDDDD 1712
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 28.5 bits (62), Expect = 2.0
Identities = 14/52 (26%), Positives = 25/52 (48%)
Query: 92 ILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
+ K + +S+ A GE H ++ G ++E ++ DDD+D DD
Sbjct: 190 VAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDD 241
>gi|62821787 COBL-like 1 [Homo sapiens]
Length = 1166
Score = 28.5 bits (62), Expect = 2.0
Identities = 25/107 (23%), Positives = 47/107 (43%), Gaps = 9/107 (8%)
Query: 17 NENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKLRKKVWI---NT 73
++N E+++ DGQE V+ NG+ +K L + ++ ++ + NT
Sbjct: 510 SQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVQNEIIVYPENT 569
Query: 74 SDIILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDT 120
D + G++ + N V N D E P +++ +ETDT
Sbjct: 570 EDNMKNGVKKTEINVEGVAKNNNID------MEVERPSNSEAHETDT 610
>gi|7662072 zinc finger and BTB domain containing 39 [Homo sapiens]
Length = 712
Score = 28.5 bits (62), Expect = 2.0
Identities = 11/22 (50%), Positives = 15/22 (68%)
Query: 122 GPGDDDEIQFDDIGDDDEDIDD 143
G G DE+Q +D+GDDD +D
Sbjct: 287 GFGQMDELQLEDLGDDDLQFED 308
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 28.1 bits (61), Expect = 2.7
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Query: 113 AKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
A+I + D G DDE +FDD DDD D +D
Sbjct: 162 AEIEDDDE--EGFDDEDEFDDEHDDDLDTED 190
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 28.1 bits (61), Expect = 2.7
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Query: 113 AKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
A+I + D G DDE +FDD DDD D +D
Sbjct: 162 AEIEDDDE--EGFDDEDEFDDEHDDDLDTED 190
>gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]
Length = 495
Score = 27.7 bits (60), Expect = 3.5
Identities = 12/32 (37%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 112 HAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
+ +N + ++ DDD+ DD DDD++IDD
Sbjct: 247 NCSVNGSSSYHSDDDDD---DDDDDDDDNIDD 275
>gi|19924159 RPB5-mediating protein isoform a [Homo sapiens]
Length = 535
Score = 27.7 bits (60), Expect = 3.5
Identities = 12/32 (37%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 112 HAKINETDTFGPGDDDEIQFDDIGDDDEDIDD 143
+ +N + ++ DDD+ DD DDD++IDD
Sbjct: 287 NCSVNGSSSYHSDDDDD---DDDDDDDDNIDD 315
>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
Length = 1621
Score = 27.3 bits (59), Expect = 4.5
Identities = 10/21 (47%), Positives = 14/21 (66%)
Query: 2 PKNKGKGGKNRRRGKNENESE 22
PK KG+G K R+ +ENE +
Sbjct: 1532 PKGKGRGAKKRKASGSENEGD 1552
>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
sapiens]
Length = 890
Score = 27.3 bits (59), Expect = 4.5
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 6/64 (9%)
Query: 10 KNRRRGKNENESEKR------ELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRG 63
K+R++GK + +++R + + GQE QV+K E DG+ RL +
Sbjct: 2 KSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVSS 61
Query: 64 KLRK 67
++K
Sbjct: 62 NIQK 65
>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
sapiens]
Length = 1101
Score = 27.3 bits (59), Expect = 4.5
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 6/64 (9%)
Query: 10 KNRRRGKNENESEKR------ELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRG 63
K+R++GK + +++R + + GQE QV+K E DG+ RL +
Sbjct: 2 KSRQKGKKKGSAKERVFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVDGIYRLSGVSS 61
Query: 64 KLRK 67
++K
Sbjct: 62 NIQK 65
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 7 KGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKL 65
+G KN +E+ E + + + +++K +GNG E G K H +GKL
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKL 61
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 7 KGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKL 65
+G KN +E+ E + + + +++K +GNG E G K H +GKL
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKL 61
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 7 KGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKL 65
+G KN +E+ E + + + +++K +GNG E G K H +GKL
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKL 61
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 7 KGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEALCFDGVKRLCHIRGKL 65
+G KN +E+ E + + + +++K +GNG E G K H +GKL
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKL 61
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 26.9 bits (58), Expect = 5.9
Identities = 11/23 (47%), Positives = 13/23 (56%)
Query: 41 MLGNGRLEALCFDGVKRLCHIRG 63
+ GN R E C D +K L HI G
Sbjct: 456 LYGNDRFEGYCIDLLKELAHILG 478
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 26.9 bits (58), Expect = 5.9
Identities = 11/22 (50%), Positives = 14/22 (63%)
Query: 123 PGDDDEIQFDDIGDDDEDIDDI 144
P DDE D+ DD+ED DD+
Sbjct: 646 PNSDDEDDGDEKEDDEEDKDDV 667
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 26.9 bits (58), Expect = 5.9
Identities = 15/68 (22%), Positives = 31/68 (45%)
Query: 76 IILVGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIG 135
+++ G D Q++ D + A+E E + N +T+G D++ ++ G
Sbjct: 596 LVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDG 655
Query: 136 DDDEDIDD 143
++ E DD
Sbjct: 656 EEQEVRDD 663
>gi|189217919 protein associated with topoisomerase II homolog 1
[Homo sapiens]
Length = 770
Score = 26.9 bits (58), Expect = 5.9
Identities = 10/20 (50%), Positives = 15/20 (75%)
Query: 123 PGDDDEIQFDDIGDDDEDID 142
P D+DE F +G++DE+ID
Sbjct: 11 PLDEDEDAFQGLGEEDEEID 30
>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
2 [Homo sapiens]
Length = 2896
Score = 26.6 bits (57), Expect = 7.7
Identities = 14/49 (28%), Positives = 26/49 (53%)
Query: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEA 49
+P++K K R +NES + ++ + GQ+ A+V+ G+ EA
Sbjct: 2784 IPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEA 2832
>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
1 [Homo sapiens]
Length = 3256
Score = 26.6 bits (57), Expect = 7.7
Identities = 14/49 (28%), Positives = 26/49 (53%)
Query: 1 MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEA 49
+P++K K R +NES + ++ + GQ+ A+V+ G+ EA
Sbjct: 3144 IPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEA 3192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.139 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,908,561
Number of Sequences: 37866
Number of extensions: 247052
Number of successful extensions: 979
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 872
Number of HSP's gapped (non-prelim): 99
length of query: 144
length of database: 18,247,518
effective HSP length: 92
effective length of query: 52
effective length of database: 14,763,846
effective search space: 767719992
effective search space used: 767719992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.