Guide to the Human Genome
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Name: NPM1 Sequence: fasta or formatted (259aa) NCBI GI: 83641870
Description:

nucleophosmin 1 isoform 3

Referenced in:

Centromere Proteins
Nucleus and Nucleolus
Receptor Tyrosine Kinases
p53 Pathway

Other entries for this name:
alt prot [294aa] nucleophosmin 1 isoform 1
alt prot [265aa] nucleophosmin 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9         18           2
 C cysteine            0.8          2           1
 D aspartate          12.4         32           6
 E glutamate          11.2         29           4
 F phenylalanine       1.9          5           1
 G glycine             6.2         16           3
 H histidine           2.3          6           1
 I isoleucine          3.1          8           1
 K lysine             11.2         29           2
 L leucine             6.2         16           2
 M methionine          2.7          7           1
 N asparagine          2.7          7           1
 P proline             6.2         16           2
 Q glutamine           3.9         10           1
 R arginine            2.3          6           1
 S serine              9.3         24           2
 T threonine           3.5          9           1
 V valine              6.2         16           2
 W tryptophan          0.0          0           0
 Y tyrosine            1.2          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nucleophosmin 1 isoform 3 
NPM1                  0.990   nucleophosmin 1 isoform 1 
NPM1                  0.844   nucleophosmin 1 isoform 2 
LOC440577             0.668   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.668   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.668   PREDICTED: similar to nucleophosmin 1 
NPM3                  0.164   nucleophosmin/nucleoplasmin 3 
NPM2                  0.136   nucleoplasmin 2 
NCL                   0.097   nucleolin 
BAZ2B                 0.073   bromodomain adjacent to zinc finger domain, 2B [Homo...
UBTF                  0.065   upstream binding transcription factor, RNA polymera...
UBTF                  0.065   upstream binding transcription factor, RNA polymera...
UBTF                  0.065   upstream binding transcription factor, RNA polymerase...
ATAD2                 0.061   ATPase family, AAA domain containing 2 
EIF3CL                0.055   eukaryotic translation initiation factor 3, subunit...
EIF3C                 0.055   eukaryotic translation initiation factor 3, subunit ...
EIF3C                 0.055   eukaryotic translation initiation factor 3, subunit C...
AEBP2                 0.055   AE binding protein 2 isoform b 
AEBP2                 0.055   AE binding protein 2 isoform a 
MTERFD2               0.053   MTERF domain containing 2 
NOLC1                 0.053   nucleolar and coiled-body phosphoprotein 1 
CASZ1                 0.051   castor homolog 1, zinc finger isoform a 
SETD1B                0.049   SET domain containing 1B 
LOC645490             0.049   PREDICTED: similar to hCG1991922 
MYT1                  0.049   myelin transcription factor 1 
GTF2F1                0.049   general transcription factor IIF, polypeptide 1, 74...
RBM28                 0.049   RNA binding motif protein 28 
CENPB                 0.047   centromere protein B 
ESF1                  0.047   ABT1-associated protein 
TAF7L                 0.047   TATA box binding protein-associated factor, RNA poly...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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