Guide to the Human Genome
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Name: NPM1 Sequence: fasta or formatted (294aa) NCBI GI: 10835063
Description:

nucleophosmin 1 isoform 1

Referenced in:

Centromere Proteins
Nucleus and Nucleolus
Receptor Tyrosine Kinases
p53 Pathway

Other entries for this name:
alt prot [265aa] nucleophosmin 1 isoform 2
alt prot [259aa] nucleophosmin 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         19           2
 C cysteine            1.0          3           1
 D aspartate          11.6         34           6
 E glutamate          10.5         31           4
 F phenylalanine       2.4          7           1
 G glycine             6.1         18           3
 H histidine           1.7          5           1
 I isoleucine          3.4         10           1
 K lysine             11.2         33           2
 L leucine             6.5         19           2
 M methionine          2.7          8           1
 N asparagine          3.1          9           1
 P proline             5.8         17           2
 Q glutamine           4.4         13           1
 R arginine            2.7          8           1
 S serine              8.8         26           2
 T threonine           3.4         10           1
 V valine              6.1         18           2
 W tryptophan          0.7          2           1
 Y tyrosine            1.4          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nucleophosmin 1 isoform 1 
NPM1                  0.873   nucleophosmin 1 isoform 2 
NPM1                  0.862   nucleophosmin 1 isoform 3 
LOC440577             0.582   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.582   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.582   PREDICTED: similar to nucleophosmin 1 
NPM3                  0.143   nucleophosmin/nucleoplasmin 3 
NPM2                  0.118   nucleoplasmin 2 
NCL                   0.085   nucleolin 
BAZ2B                 0.063   bromodomain adjacent to zinc finger domain, 2B [Homo...
UBTF                  0.056   upstream binding transcription factor, RNA polymera...
UBTF                  0.056   upstream binding transcription factor, RNA polymera...
UBTF                  0.056   upstream binding transcription factor, RNA polymerase...
ATAD2                 0.053   ATPase family, AAA domain containing 2 
ZRANB2                0.051   zinc finger protein 265 isoform 1 
ZRANB2                0.051   zinc finger protein 265 isoform 2 
EIF3CL                0.048   eukaryotic translation initiation factor 3, subunit...
EIF3C                 0.048   eukaryotic translation initiation factor 3, subunit ...
EIF3C                 0.048   eukaryotic translation initiation factor 3, subunit C...
AEBP2                 0.048   AE binding protein 2 isoform b 
AEBP2                 0.048   AE binding protein 2 isoform a 
NOLC1                 0.048   nucleolar and coiled-body phosphoprotein 1 
MTERFD2               0.046   MTERF domain containing 2 
MYT1                  0.044   myelin transcription factor 1 
DEK                   0.044   DEK oncogene isoform 2 
DEK                   0.044   DEK oncogene isoform 1 
CASZ1                 0.044   castor homolog 1, zinc finger isoform a 
HP1BP3                0.042   HP1-BP74 
SETD1B                0.042   SET domain containing 1B 
LOC645490             0.042   PREDICTED: similar to hCG1991922 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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