Guide to the Human Genome
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Name: NPM1 Sequence: fasta or formatted (265aa) NCBI GI: 40353734
Description:

nucleophosmin 1 isoform 2

Referenced in:

Centromere Proteins
Nucleus and Nucleolus
Receptor Tyrosine Kinases
p53 Pathway

Other entries for this name:
alt prot [294aa] nucleophosmin 1 isoform 1
alt prot [259aa] nucleophosmin 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.4         17           2
 C cysteine            1.1          3           1
 D aspartate          12.1         32           6
 E glutamate          11.7         31           4
 F phenylalanine       2.6          7           1
 G glycine             6.4         17           3
 H histidine           1.9          5           1
 I isoleucine          3.4          9           1
 K lysine             10.6         28           2
 L leucine             7.2         19           2
 M methionine          3.0          8           1
 N asparagine          2.3          6           1
 P proline             5.3         14           2
 Q glutamine           4.2         11           1
 R arginine            2.3          6           1
 S serine              7.5         20           2
 T threonine           3.0          8           1
 V valine              6.8         18           2
 W tryptophan          0.8          2           1
 Y tyrosine            1.5          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   nucleophosmin 1 isoform 2 
NPM1                  0.971   nucleophosmin 1 isoform 1 
NPM1                  0.818   nucleophosmin 1 isoform 3 
LOC440577             0.641   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.641   PREDICTED: similar to nucleophosmin 1 
LOC440577             0.641   PREDICTED: similar to nucleophosmin 1 
NPM3                  0.159   nucleophosmin/nucleoplasmin 3 
NPM2                  0.118   nucleoplasmin 2 
NCL                   0.096   nucleolin 
UBTF                  0.059   upstream binding transcription factor, RNA polymera...
UBTF                  0.059   upstream binding transcription factor, RNA polymera...
UBTF                  0.059   upstream binding transcription factor, RNA polymerase...
BAZ2B                 0.053   bromodomain adjacent to zinc finger domain, 2B [Homo...
ATAD2                 0.053   ATPase family, AAA domain containing 2 
MTERFD2               0.051   MTERF domain containing 2 
CASZ1                 0.049   castor homolog 1, zinc finger isoform a 
RBM28                 0.049   RNA binding motif protein 28 
NOLC1                 0.047   nucleolar and coiled-body phosphoprotein 1 
LOC645490             0.047   PREDICTED: similar to hCG1991922 
CENPB                 0.045   centromere protein B 
EIF3CL                0.045   eukaryotic translation initiation factor 3, subunit...
EIF3C                 0.045   eukaryotic translation initiation factor 3, subunit ...
EIF3C                 0.045   eukaryotic translation initiation factor 3, subunit C...
ESF1                  0.045   ABT1-associated protein 
CHIC1                 0.043   cysteine-rich hydrophobic domain 1 
HMGB1L1               0.043   high-mobility group box 1-like 1 
ZBTB7C                0.043   zinc finger and BTB domain containing 7C 
LOC645490             0.041   PREDICTED: similar to hCG1991922 
GTF2F1                0.041   general transcription factor IIF, polypeptide 1, 74...
LOC645490             0.039   PREDICTED: similar to hCG1991922 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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