Guide to the Human Genome
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Name: TOP2B Sequence: fasta or formatted (1621aa) NCBI GI: 19913408
Description:

DNA topoisomerase II, beta isozyme

Referenced in:

Replication Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         96           3
 C cysteine            1.0         17           1
 D aspartate           7.2        117           6
 E glutamate           7.8        126           3
 F phenylalanine       4.4         71           2
 G glycine             6.5        105           3
 H histidine           1.6         26           2
 I isoleucine          5.0         81           2
 K lysine             11.5        187           4
 L leucine             7.5        122           2
 M methionine          2.1         34           2
 N asparagine          4.9         79           2
 P proline             4.5         73           2
 Q glutamine           3.3         54           2
 R arginine            3.9         63           2
 S serine              7.1        115           3
 T threonine           5.4         87           3
 V valine              6.4        103           2
 W tryptophan          1.2         19           1
 Y tyrosine            2.8         46           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA topoisomerase II, beta isozyme 
TOP2A                 0.645   DNA topoisomerase II, alpha isozyme 
NCL                   0.011   nucleolin 
IWS1                  0.011   IWS1 homolog 
DSPP                  0.011   dentin sialophosphoprotein preproprotein 
AFF4                  0.009   ALL1 fused gene from 5q31 
RBBP6                 0.009   retinoblastoma-binding protein 6 isoform 2 
RBBP6                 0.009   retinoblastoma-binding protein 6 isoform 1 
ACRC                  0.009   ACRC protein 
NOLC1                 0.009   nucleolar and coiled-body phosphoprotein 1 
NEFH                  0.009   neurofilament, heavy polypeptide 200kDa 
FAM21C                0.008   hypothetical protein LOC253725 
SETD1A                0.008   SET domain containing 1A 
NEFM                  0.008   neurofilament, medium polypeptide 150kDa isoform 1 ...
SFRS16                0.008   splicing factor, arginine/serine-rich 16 
HDGF2                 0.008   hepatoma-derived growth factor-related protein 2 iso...
HDGF2                 0.008   hepatoma-derived growth factor-related protein 2 iso...
SETD1B                0.007   SET domain containing 1B 
EIF5B                 0.007   eukaryotic translation initiation factor 5B 
ABCF1                 0.007   ATP-binding cassette, sub-family F, member 1 isoform...
RSF1                  0.007   remodeling and spacing factor 1 
MLLT1                 0.007   myeloid/lymphoid or mixed-lineage leukemia (trithora...
FAM21A                0.007   hypothetical protein LOC387680 
TRDN                  0.007   triadin 
FAM21B                0.007   hypothetical protein LOC55747 
NEFM                  0.007   neurofilament, medium polypeptide 150kDa isoform 2 ...
CYLC1                 0.007   cylicin, basic protein of sperm head cytoskeleton 1...
PCLO                  0.007   piccolo isoform 2 
PCLO                  0.007   piccolo isoform 1 
CHD7                  0.007   chromodomain helicase DNA binding protein 7 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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