Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 32967311
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32967311 ephrin receptor EphA2 [Homo sapiens]
(976 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 1996 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1027 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1015 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 993 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 972 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 971 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 940 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 916 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 911 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 909 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 905 0.0
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 885 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 875 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 814 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 760 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 672 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 468 e-131
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 414 e-115
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 273 7e-73
gi|31657140 insulin receptor-related receptor precursor [Homo sa... 244 3e-64
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 228 2e-59
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo... 226 6e-59
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo... 226 6e-59
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 226 8e-59
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... 224 3e-58
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... 224 3e-58
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 221 2e-57
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap... 221 3e-57
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi... 221 3e-57
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 219 8e-57
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 1996 bits (5172), Expect = 0.0
Identities = 976/976 (100%), Positives = 976/976 (100%)
Query: 1 MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMN 60
MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMN
Sbjct: 1 MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMN 60
Query: 61 DMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFN 120
DMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFN
Sbjct: 61 DMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFN 120
Query: 121 LYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYL 180
LYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYL
Sbjct: 121 LYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYL 180
Query: 181 AFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGG 240
AFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGG
Sbjct: 181 AFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGG 240
Query: 241 EEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPS 300
EEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPS
Sbjct: 241 EEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPS 300
Query: 301 PEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDI 360
PEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDI
Sbjct: 301 PEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDI 360
Query: 361 VYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSG 420
VYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSG
Sbjct: 361 VYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSG 420
Query: 421 LVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
LVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN
Sbjct: 421 LVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
Query: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGG 540
SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGG
Sbjct: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGG 540
Query: 541 VAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQA 600
VAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQA
Sbjct: 541 VAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQA 600
Query: 601 VLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDF 660
VLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDF
Sbjct: 601 VLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDF 660
Query: 661 LGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGML 720
LGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGML
Sbjct: 661 LGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGML 720
Query: 721 RGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIP 780
RGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIP
Sbjct: 721 RGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIP 780
Query: 781 IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPM 840
IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPM
Sbjct: 781 IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPM 840
Query: 841 DCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSG 900
DCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSG
Sbjct: 841 DCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSG 900
Query: 901 SEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAY 960
SEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAY
Sbjct: 901 SEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAY 960
Query: 961 SLLGLKDQVNTVGIPI 976
SLLGLKDQVNTVGIPI
Sbjct: 961 SLLGLKDQVNTVGIPI 976
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 1027 bits (2656), Expect = 0.0
Identities = 525/984 (53%), Positives = 680/984 (69%), Gaps = 24/984 (2%)
Query: 11 ALLWGCALAAAA-----AAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPI 64
A LW C L AA A+ EV LLD G+LGW+ P GW+ + + N PI
Sbjct: 38 APLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPI 96
Query: 65 YMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA 124
+ Y VC VM +Q+NWL T+W+ A RIFIELKFT+RDCNS PGG +CKETFN+YY
Sbjct: 97 HTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYF 156
Query: 125 ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQD 184
ESD G N ++ + KIDTIA DE D R +KLN E R VGPL++KGFYLAFQD
Sbjct: 157 ESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQD 216
Query: 185 IGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPR 244
+GAC+AL+SVRVYYKKCP +++ LA FP+TI G+D+ L V+G+CV+H+V E P+
Sbjct: 217 VGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTD---EPPK 273
Query: 245 MHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
MHC+ +GEWLVPIG+C+C+AGYE+ CQ C PGFFK C +CP H+ E +
Sbjct: 274 MHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEAS 333
Query: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
TSC CE+ +FR DP +M CTRPPSAP + V L W PP D+GGR+D+ Y +
Sbjct: 334 TSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYI 393
Query: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
C++C +G C C VRY GL TSV + DL H NYTF +EA NGVS L
Sbjct: 394 ACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPG 453
Query: 424 SRSFRTASVSINQTEPPKVR--LEGR-STTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
+R + + +V+ NQ P V +G+ + S+S+SW P + +YE+ Y +K
Sbjct: 454 ARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET 513
Query: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTL-----SPEGSGNL 535
SY + +++ ++T + L P + Y+ Q++A T G G S+ EF+T S + S
Sbjct: 514 SYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIP 573
Query: 536 AVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPED--VYFSKSE-QLKPLKTYVDPH 592
+ V VGV+LL V+ GV RR +A+Q PE+ ++F +L ++TY+DPH
Sbjct: 574 VIAVSVTVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPH 632
Query: 593 TYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGY 652
TYEDPNQAV +F EI SC+T ++VIGAGEFGEV G LK GK+E+PVAIKTLK GY
Sbjct: 633 TYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLP-GKRELPVAIKTLKVGY 691
Query: 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712
TEKQR DFLGEA IMGQF H NII LEGV++K KP+MI+TEYMENG+LD FL++ DG+F+
Sbjct: 692 TEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT 751
Query: 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATY 772
V+QLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEA Y
Sbjct: 752 VIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAY 811
Query: 773 TTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIND 832
TT GGKIPIRWTAPEAI++RKFTSASDVWS+GIVMWEV++YGERPYWE++N +V+KA+ +
Sbjct: 812 TTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEE 871
Query: 833 GFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVS 892
G+RLP+PMDCP+A+YQLM+ CWQ+ER RPKF +IV++LDKLIR P SLKTL + RVS
Sbjct: 872 GYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVS 931
Query: 893 IRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLP 952
L S +R+V EWLE+IKM +YTE FM GY++++ V Q+T +D++R+GV L
Sbjct: 932 NLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLV 991
Query: 953 GHQKRIAYSLLGLKDQVNTVGIPI 976
GHQK+I SL +K Q+ +P+
Sbjct: 992 GHQKKIMNSLQEMKVQLVNGMVPL 1015
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 1015 bits (2625), Expect = 0.0
Identities = 524/1005 (52%), Positives = 680/1005 (67%), Gaps = 44/1005 (4%)
Query: 11 ALLWGCALAAAA-----AAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPI 64
A LW C L AA A+ EV LLD G+LGW+ P GW+ + + N PI
Sbjct: 38 APLWTCLLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKN-GWEEIGEVDENYAPI 96
Query: 65 YMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYA 124
+ Y VC VM +Q+NWL T+W+ A RIFIELKFT+RDCNS PGG +CKETFN+YY
Sbjct: 97 HTYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYF 156
Query: 125 ESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQD 184
ESD G N ++ + KIDTIA DE D R +KLN E R VGPL++KGFYLAFQD
Sbjct: 157 ESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQD 216
Query: 185 IGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPR 244
+GAC+AL+SVRVYYKKCP +++ LA FP+TI G+D+ L V+G+CV+H+V E P+
Sbjct: 217 VGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTD---EPPK 273
Query: 245 MHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
MHC+ +GEWLVPIG+C+C+AGYE+ CQ C PGFFK C +CP H+ E +
Sbjct: 274 MHCSAEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEAS 333
Query: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
TSC CE+ +FR DP +M CTRPPSAP + V L W PP D+GGR+D+ Y +
Sbjct: 334 TSCVCEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYI 393
Query: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
C++C +G C C VRY GL TSV + DL H NYTF +EA NGVS L
Sbjct: 394 ACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPG 453
Query: 424 SRSFRTASVSINQTEPPKVR--LEGR-STTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
+R + + +V+ NQ P V +G+ + S+S+SW P + +YE+ Y +K
Sbjct: 454 ARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET 513
Query: 481 SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTL-----SPEGSGNL 535
SY + +++ ++T + L P + Y+ Q++A T G G S+ EF+T S + S
Sbjct: 514 SYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIP 573
Query: 536 AVIGGVAVGVVLLLVLAGVGFF---------------------IHRRRKNQRARQSPED- 573
+ V VGV+LL V+ GV + R +A+Q PE+
Sbjct: 574 VIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEE 633
Query: 574 -VYFSKSE-QLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGM 631
++F +L ++TY+DPHTYEDPNQAV +F EI SC+T ++VIGAGEFGEV G
Sbjct: 634 KMHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGR 693
Query: 632 LKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMII 691
LK GK+E+PVAIKTLK GYTEKQR DFLGEA IMGQF H NII LEGV++K KP+MI+
Sbjct: 694 LKLP-GKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIV 752
Query: 692 TEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNL 751
TEYMENG+LD FL++ DG+F+V+QLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNL
Sbjct: 753 TEYMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNL 812
Query: 752 VCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVM 811
VCKVSDFGLSRVLEDDPEA YTT GGKIPIRWTAPEAI++RKFTSASDVWS+GIVMWEV+
Sbjct: 813 VCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVV 872
Query: 812 TYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSIL 871
+YGERPYWE++N +V+KA+ +G+RLP+PMDCP+A+YQLM+ CWQ+ER RPKF +IV++L
Sbjct: 873 SYGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932
Query: 872 DKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYT 931
DKLIR P SLKTL + RVS L S +R+V EWLE+IKM +YTE FM GY+
Sbjct: 933 DKLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYS 992
Query: 932 AIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIPI 976
+++ V Q+T +D++R+GV L GHQK+I SL +K Q+ +P+
Sbjct: 993 SMDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQLVNGMVPL 1037
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 993 bits (2566), Expect = 0.0
Identities = 504/979 (51%), Positives = 659/979 (67%), Gaps = 28/979 (2%)
Query: 13 LWGCALAAAAAAQG-KEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMYSVC 70
+W A AQ KEV+LLD A EL W++ P GW+ + + N PI Y VC
Sbjct: 16 IWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSP-PNGWEEISGLDENYTPIRTYQVC 74
Query: 71 NVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDY 130
VM +Q+NWLRTNW+ +G A+RIF+ELKFT+RDCNS PG +CKETFNLYY E+D D
Sbjct: 75 QVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDT 134
Query: 131 GTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVA 190
G N ++ L+ KIDTIA DE D R +KLN E R +GPL++KGFYLAFQD+GAC+A
Sbjct: 135 GRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIA 194
Query: 191 LLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVD 250
L+SV+VYYKKC +++ LA FP+T+ GS+ SL V GTCV A PRMHC+ +
Sbjct: 195 LVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAE-EEAENAPRMHCSAE 253
Query: 251 GEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECE 310
GEWLVPIG+C+C+AGY++ D C+ C GF+K + + C CP H+ EG++ CECE
Sbjct: 254 GEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECE 313
Query: 311 EGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCW 370
+G++RAP DP + CTRPPSAP L V L W+PP D+GGR D+ Y + C++C
Sbjct: 314 DGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCS 373
Query: 371 PESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRT 429
E GEC PC +++ Y GL VTV DL H NYTF VEA NGVS L S R F
Sbjct: 374 WEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAA 433
Query: 430 ASVSINQTEPPKVR---LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGD-SNSYNVR 485
S++ Q P +V E S+ +SW P + +YE+ Y +K +Y+
Sbjct: 434 VSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTV 493
Query: 486 RTEGFSVTLDDLAPDTTYLVQVQALTQEGQG-------------AGSKVHEFQTLSPEGS 532
+T+ S ++++L P T Y+ Q++A T G G A K+ E +S E
Sbjct: 494 KTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSE-Q 552
Query: 533 GNLAVIGGVAVGVVLLLVLAGVGFFIHRRR--KNQRARQSPEDVYFSKSEQLKPLKTYVD 590
+ +I VAV ++LV GF I RR ++ ++ E++YF + KTY+D
Sbjct: 553 NPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF--KFPGTKTYID 610
Query: 591 PHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKA 650
P TYEDPN+AV +F E+ SC+ ++VIGAGEFGEV G LK GK++V VAIKTLK
Sbjct: 611 PETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLP-GKRDVAVAIKTLKV 669
Query: 651 GYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGE 710
GYTEKQR DFL EA IMGQF H N++ LEGV+++ KP+MI+ E+MENGALD FLR+ DG+
Sbjct: 670 GYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQ 729
Query: 711 FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEA 770
F+V+QLVGMLRGIAAGM+YLA+M YVHRDLAARNILVNSNLVCKVSDFGLSRV+EDDPEA
Sbjct: 730 FTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEA 789
Query: 771 TYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI 830
YTT+GGKIP+RWTAPEAI YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+KAI
Sbjct: 790 VYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 849
Query: 831 NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPR 890
+G+RLP PMDCP+ ++QLM+ CWQ+ERA RPKF IV ILDK+IR P+SLKT R
Sbjct: 850 EEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSR 909
Query: 891 VSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVR 950
L + + F +V EWL++IKM++Y ++F AAGY ++E V +MT +D+ +G+
Sbjct: 910 PISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGIT 969
Query: 951 LPGHQKRIAYSLLGLKDQV 969
L GHQK+I S+ ++ Q+
Sbjct: 970 LVGHQKKIMSSIQTMRAQM 988
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 972 bits (2512), Expect = 0.0
Identities = 499/964 (51%), Positives = 651/964 (67%), Gaps = 24/964 (2%)
Query: 28 EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGDQDNWLRTNWV 86
EV LLD GELGW+++P GW+ + + PI Y VCNVM Q+NWLRTNWV
Sbjct: 29 EVNLLDSKTIQGELGWISYP-SHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWV 87
Query: 87 YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146
R A++I++ELKFT+RDCNS P +CKETFNLYY ESD D+G F++ FTKIDTIA
Sbjct: 88 PRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIA 147
Query: 147 PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206
DE D R +KLN E R VGP+ +KGFYLAFQD+GACVAL+SVRVY+KKCP ++
Sbjct: 148 ADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK 207
Query: 207 GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266
LA FP+T+ D+ SL V G+CV+++ + PRM+C+ +GEWLVPIG+C C AGY
Sbjct: 208 NLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE---DPPRMYCSTEGEWLVPIGKCSCNAGY 263
Query: 267 EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326
E+ CQAC PGF+K C +CP H+ +G+ +C CE +FRA +DP SM CT
Sbjct: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
Query: 327 RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
RPPS+P + + V L W+ P D+GGR+D+ +++ C++C +C PC +VR+
Sbjct: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
Query: 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRTASVSINQTEPPKV--- 442
GLT T+VTV+DL H NYTF ++A NGVS L + R F S++ NQ P V
Sbjct: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
Query: 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN-SYNVRRTEGFSVTLDDLAPDT 501
+ + S S+S+SW P + YEV Y +K + SY + R G +VT+ L PDT
Sbjct: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
Query: 502 TYLVQVQALTQEGQGAGSKVHEFQT------LSPEGSGNLAVIGGVAVGVVLLLVLAGV- 554
Y+ Q++A T G G S+ EF+T +S E S + + AV ++LL V+ V
Sbjct: 504 IYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLTVVIYVL 563
Query: 555 -GFFIHRRRKNQRARQSPEDVYFSKSE-QLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSC 612
G F + K+ + ++F +L L+TYVDPHTYEDP QAV +F E+ +
Sbjct: 564 IGRFCGYKSKHGADEKR---LHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDATN 620
Query: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSH 672
++ KV+GAGEFGEV G LK S KKE+ VAIKTLK GYTEKQR DFLGEA IMGQF H
Sbjct: 621 ISIDKVVGAGEFGEVCSGRLKLPS-KKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
Query: 673 HNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLAN 732
NIIRLEGV++K KP+MI+TEYMENG+LD FLR+ D +F+V+QLVGMLRGIA+GMKYL++
Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
Query: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYR 792
M YVHRDLAARNIL+NSNLVCKVSDFGLSRVLEDDPEA YTT GGKIPIRWT+PEAI+YR
Sbjct: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYR 799
Query: 793 KFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQ 852
KFTSASDVWS+GIV+WEVM+YGERPYWE+SN +V+KA+++G+RLP PMDCP+A+YQLM+
Sbjct: 800 KFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLD 859
Query: 853 CWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEW 912
CWQ++R RPKF IVSILDKLIR P SLK + R S L S + FRT +W
Sbjct: 860 CWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDW 919
Query: 913 LESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTV 972
L + E F Y++ + + +++ DD+K++GV + G QK+I S+ L+ Q
Sbjct: 920 LNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSKNG 979
Query: 973 GIPI 976
+P+
Sbjct: 980 PVPV 983
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 971 bits (2511), Expect = 0.0
Identities = 502/978 (51%), Positives = 663/978 (67%), Gaps = 25/978 (2%)
Query: 8 ACFALLWGC--ALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM--P 63
A F+ L+G A+ + EV LLD + GELGW+ P GW+ + +IM++ P
Sbjct: 8 ALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEV-SIMDEKNTP 66
Query: 64 IYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYY 123
I Y VCNVM Q+NWLRT+W+ R A+R++IE+KFT+RDCNS PG +CKETFNLYY
Sbjct: 67 IRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYY 126
Query: 124 AESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQ 183
ESD D ++ F KIDTIA DE D R +KLN E R VGPL++KGFYLAFQ
Sbjct: 127 YESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQ 186
Query: 184 DIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP 243
D+GAC+AL+SVRV+YKKCP ++ LA FP+TI G+D SL V G+CV+++ + P
Sbjct: 187 DVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK---DVP 243
Query: 244 RMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEG 303
+M+C DGEWLVPIG CLC AG+E+ CQAC G++K ++++ C +CP H+ EG
Sbjct: 244 KMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEG 303
Query: 304 ATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYS 363
ATSC C+ GFFRA D ASMPCTRPPSAP L + V L W+ PQ++GGR+DI Y+
Sbjct: 304 ATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYN 363
Query: 364 VTCEQCWP-ESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLV 422
V C++C + +C PC + V Y+ +GL T V+++DL H NYTF + A NGVS
Sbjct: 364 VVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYN 423
Query: 423 TSRSFRTA-SVSINQTEPPKVRL-EGRSTT--SLSVSWSIPPPQQSRVWKYEVTYRKKGD 478
+ + +V+ NQ P + L + + T S++++W P + +YEV Y +K
Sbjct: 424 PNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQ 483
Query: 479 SN-SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQT------LSPEG 531
+ SY + RT + + L P T+Y+ V+A T G G S+ E T + +G
Sbjct: 484 NERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDG 543
Query: 532 SGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDP 591
+ + ++ V+ VVL+++L RR K +A+Q ++ + + ++TYVDP
Sbjct: 544 ANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADE----EKHLNQGVRTYVDP 599
Query: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651
TYEDPNQAV +F EI SC+ +KVIG GEFGEV G LK GK+E+ VAIKTLKAG
Sbjct: 600 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVP-GKREICVAIKTLKAG 658
Query: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711
YT+KQR DFL EA IMGQF H NII LEGV++K KP+MIITEYMENG+LD FLR+ DG F
Sbjct: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRF 718
Query: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAT 771
+V+QLVGMLRGI +GMKYL++M+YVHRDLAARNILVNSNLVCKVSDFG+SRVLEDDPEA
Sbjct: 719 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 778
Query: 772 YTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIN 831
YTT GGKIPIRWTAPEAI+YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+KAI
Sbjct: 779 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 838
Query: 832 DGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRV 891
+G+RLP PMDCP A++QLM+ CWQ+ER+ RPKF IV++LDKLIR P+SLK R
Sbjct: 839 EGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRP 898
Query: 892 SIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRL 951
+ L S E +V +WL++IKM +Y ++F AAGYT +E VV + +D+ RIG+
Sbjct: 899 NTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITA 958
Query: 952 PGHQKRIAYSLLGLKDQV 969
HQ +I S+ ++ Q+
Sbjct: 959 ITHQNKILSSVQAMRTQM 976
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 940 bits (2430), Expect = 0.0
Identities = 492/1000 (49%), Positives = 651/1000 (65%), Gaps = 71/1000 (7%)
Query: 28 EVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMYSVCNVMSGDQDNWLRTNWV 86
+VVLLD GELGW T+P GWD + + ++ PI+ Y VCNVM +Q+NWLRTNW+
Sbjct: 128 QVVLLDTTTVLGELGWKTYPLN-GWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWI 186
Query: 87 YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146
R A++I++E+KFT+RDCNS P +CKETFNL+Y ESD +G F+ +TKIDTIA
Sbjct: 187 SRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTIA 246
Query: 147 PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206
DE D R +KLN E R VGP+ RKGFYLAFQDIGAC+AL+SVRV+YKKCP ++
Sbjct: 247 ADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVR 306
Query: 207 GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266
LA FP+TI D+ SL V G+CV A + P+++C DG+WLVP+G+C+C GY
Sbjct: 307 NLAMFPDTIPRVDSSSLVEVRGSCVKSA---EERDTPKLYCGADGDWLVPLGRCICSTGY 363
Query: 267 EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326
E++E +C AC PGF+K A + C +CP H+L E + C+CE+G+FRA +DP SM CT
Sbjct: 364 EEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACT 423
Query: 327 RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
RPPSAP + + L W+PP D+GGR+D+ YSV C++C ++ +C C +R+
Sbjct: 424 RPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 483
Query: 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RSFRTASVSINQTEPP---KV 442
GL SV V D H+NYTF +EA NGVS L S + F +V+ +Q P V
Sbjct: 484 PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVV 543
Query: 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVT-YRKKGDSNSYNVRRTEGFSVTLDDLAPDT 501
R + S S+++SW P + YE+ Y K+ + +Y+ R++ SV + L P T
Sbjct: 544 RKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPAT 603
Query: 502 TYLVQVQALTQEGQGAGSKVHEFQT------LSPEGSGNLAVIGGVAVGVVLLLVLAGVG 555
Y+ ++ T G S+ EF+T ++ E G + VI AVG LLV+ +
Sbjct: 604 KYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAE-QGQILVIATAAVGGFTLLVILTLF 662
Query: 556 FFIHRR-----RKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHP 610
F I R + ++ + + + + +KTY+DP TYEDP+ AV +F EI P
Sbjct: 663 FLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDP 722
Query: 611 SCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQF 670
S + ++VIGAGEFGEV G LKT GK+E+PVAIKTLK G+ ++QR DFL EA IMGQF
Sbjct: 723 SRIRIERVIGAGEFGEVCSGRLKT-PGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQF 781
Query: 671 SHHNIIRLEGVISKY------------------------------------------KPM 688
H NIIRLEGV++K +P+
Sbjct: 782 DHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPV 841
Query: 689 MIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVN 748
MI+ EYMENG+LD FLR+ DG F+V+QLVGMLRGIA+GMKYL++M YVHRDLAARNILVN
Sbjct: 842 MIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVN 901
Query: 749 SNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMW 808
SNLVCKVSDFGLSRVLEDDPEA YTT+GGKIPIRWTAPEAI+YRKF+SASD WS+GIVMW
Sbjct: 902 SNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIVMW 961
Query: 809 EVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIV 868
EVM+YGERPYWE+SN +V+ +I +G+RLP PM CP++++QLM+ CWQ+ER RPKF DIV
Sbjct: 962 EVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTDIV 1021
Query: 869 SILDKLIRAPDSLKTLADFDPRVSIRLPSTSGS--EGVPFRTVSEWLESIKMQQYTEHFM 926
S LDKLIR P +L TL + + +P + G E F TV +WL+SIKM QY +F+
Sbjct: 1022 SFLDKLIRNPSALHTLVE----DILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFV 1077
Query: 927 AAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLK 966
AAG+T + + +M+ DDI+RIGV L GHQ+RI S+ L+
Sbjct: 1078 AAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLR 1117
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 916 bits (2368), Expect = 0.0
Identities = 488/964 (50%), Positives = 634/964 (65%), Gaps = 30/964 (3%)
Query: 24 AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMPIYMYSVCNVMSG-DQDNWLR 82
A+ KEV L+D + A GELGWL P GW Q I+N P+YMY C + D D+WLR
Sbjct: 23 ARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNGTPLYMYQDCPMQGRRDTDHWLR 82
Query: 83 TNWVYRGE-AERIFIELKFTVRDCNSFPGGAS--SCKETFNLYYAESDLDYGTNFQKRLF 139
+NW+YRGE A R+ +EL+FTVRDC SFPGGA CKETFNL Y ESD D G ++ LF
Sbjct: 83 SNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLF 142
Query: 140 TKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYK 199
K+ T+A D+ D + VKLNVE S+G LTR+G YLAF + GACVAL+SVRV+Y+
Sbjct: 143 QKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQ 202
Query: 200 KCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGE-EPRMHCAVDGEWLVPIG 258
+CPE L GLA FP+T+ G L VAGTC+ HA P PRMHC+ DGEWLVP+G
Sbjct: 203 RCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVG 260
Query: 259 QCLCQAGYEK--VEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRA 316
+C C+ GYE+ +AC AC G ++ + CL CP+ + EGAT C CE G +RA
Sbjct: 261 RCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRA 320
Query: 317 PQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCW---PES 373
P + + CT PPSAP L+ G ++ LRW PP D+GGR+D+ YSV C QC +
Sbjct: 321 PGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDG 380
Query: 374 GECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTA-SV 432
G C PC V +S GLT +V V+ LEP+ NYTF VEA+NGVSGL +S T+ S+
Sbjct: 381 GPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSI 440
Query: 433 SINQTEPPK---VRLEGRSTTSLSVSWSIPPPQQSRV-WKYEVTYRKKGDSNSYNVRRTE 488
S+ E +RL + L ++W+ P+ YE+ + + V
Sbjct: 441 SMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEERYQMVLEPR 500
Query: 489 GFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGN-----LAVIGGVAV 543
V L +L PDTTY+V+V+ LT G G S HEF+T P G +AVI G+ +
Sbjct: 501 ---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLL 557
Query: 544 GVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLK 603
G LLL G+ F RR + QR ++ + E LK YVD YEDP Q L
Sbjct: 558 GAALLL---GILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALD 614
Query: 604 FTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGE 663
FT E+ P+ + VIG GEFGEVY+G L+ S + VAIKTLK Q +FL E
Sbjct: 615 FTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKT-VAIKTLKDTSPGGQWWNFLRE 673
Query: 664 AGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGI 723
A IMGQFSH +I+ LEGV++K KP+MIITE+MENGALD FLRE++ + QLV ML+GI
Sbjct: 674 ATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGI 733
Query: 724 AAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 783
A+GM YL+N NYVHRDLAARNILVN NL CKVSDFGL+R+L DD + TY T GGKIPIRW
Sbjct: 734 ASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRW 792
Query: 784 TAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCP 843
TAPEAI++R FT+ASDVWSFGIVMWEV+++G++PY E+SN EVMK+I DG+RLP P+DCP
Sbjct: 793 TAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCP 852
Query: 844 SAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEG 903
+ +Y+LM CW +RARRP F + + L++L+ P SL+T+A+FDPR+++RLPS SGS+G
Sbjct: 853 APLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDG 912
Query: 904 VPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLL 963
+P+RTVSEWLESI+M++Y HF +AG +E V+++T +D+ ++G+ LPGHQKRI S+
Sbjct: 913 IPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQ 972
Query: 964 GLKD 967
G KD
Sbjct: 973 GFKD 976
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
Length = 1005
Score = 911 bits (2354), Expect = 0.0
Identities = 469/995 (47%), Positives = 641/995 (64%), Gaps = 37/995 (3%)
Query: 13 LWGCALAAAAA----AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMY 67
LW AAAAA A EV LLD + G+ GWLT+P GWD + + PI+ Y
Sbjct: 12 LWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYP-AHGWDSINEVDESFQPIHTY 70
Query: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
VCNVMS +Q+NWLRT+WV R A R++ E+KFT+RDCNS PG +CKETFNLYY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 128 LDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA 187
D G + Q+ F KIDTIA DE +D R +KLN E RSVGPL+++GFYLAFQDIGA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 188 CVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHC 247
C+A+LS+R+YYKKCP +++ LA F E + G+D+ SL V G CV H+ + P+M+C
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS---EERDTPKMYC 247
Query: 248 AVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
+ +GEWLVPIG+C+C AGYE+ DAC AC GF+K + C CP H+ + A +C
Sbjct: 248 SAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQAC 307
Query: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
C+ ++RA DP S CTRPPSAP L + G V L W PP D GGR DI Y+ C
Sbjct: 308 HCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCR 367
Query: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTS-RS 426
+C C C + R+ L + S+ V++L HMNY+F +EA NGVS L R
Sbjct: 368 RCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRR 427
Query: 427 FRTASVSINQTEPPKV---RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKG-DSNSY 482
+++ NQ P +V R E TS+S+ W P + +YE+ Y +K + SY
Sbjct: 428 AAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSY 487
Query: 483 NVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVA 542
+ + T+ L P T Y+ QV+A T G G S+ E +T P + I +
Sbjct: 488 STLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDTRTIVWIC 547
Query: 543 VGVVLLLVLAGVGFFIHRR--------------RKNQRARQSPEDVYFSKSE---QLKPL 585
+ ++ LV+ + +R + + + Q+P V+ +L
Sbjct: 548 LTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEP 607
Query: 586 KTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAI 645
+ Y +PHTYE+P +A FT EI S + +K+IG+G+ GEV G L+ G+++VPVAI
Sbjct: 608 QFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVP-GQRDVPVAI 666
Query: 646 KTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLR 705
K LKAGYTE+QR DFL EA IMGQF H NIIRLEGV+++ + MI+TEYMENG+LD FLR
Sbjct: 667 KALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLR 726
Query: 706 EKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLE 765
DG+F+++QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSRVLE
Sbjct: 727 THDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLE 786
Query: 766 DDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHE 825
DDP+A YTT+GGKIPIRWTAPEAI++R F+SASDVWSFG+VMWEV+ YGERPYW ++N +
Sbjct: 787 DDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRD 846
Query: 826 VMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLK--- 882
V+ ++ +G+RLP PM CP A++QLM+ CW ++RA+RP+F+ IVS+LD LIR+P+SL+
Sbjct: 847 VISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATA 906
Query: 883 TLADFDPRVSIR--LPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMT 940
T++ P +R GS G TV +WL+SI+M +Y +HF A GY+++ V++M
Sbjct: 907 TVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMN 966
Query: 941 NDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVGIP 975
D++ +G+ L GHQK+I S+ ++ Q+ + P
Sbjct: 967 AQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGP 1001
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 909 bits (2350), Expect = 0.0
Identities = 480/984 (48%), Positives = 640/984 (65%), Gaps = 34/984 (3%)
Query: 15 GCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVM 73
G AL E L+D A ELGW+ HP GW+ + +M I Y VCNV
Sbjct: 7 GAALLLLPLLAAVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 74 SGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGT- 132
Q+NWLRT ++ R A RI +E+KF+VRDC+S P SCKETFNLYY E+D D T
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 133 ---NFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACV 189
N+ + + K+DTIA DE D R +K+N E RS GP++R GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 190 ALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMH 246
+L++VRV+Y+KCP ++Q A F ET++G+++ SL G+C+ +A VP +++
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-----KLY 240
Query: 247 CAVDGEWLVPIGQCLCQAGYEKVEDA--CQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
C DGEWLVPIG+C+C+AG+E VE+ C+ C G FK + C CP ++ + EGA
Sbjct: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300
Query: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
T+C C G++RA DP MPCT PSAP + + + L WTPP+DSGGRED+VY++
Sbjct: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360
Query: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
C+ C G C C +V+Y+ GLT + +SDL H YTF ++A NGV+
Sbjct: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420
Query: 424 SRSFRTASVSINQTEPPKVRLE---GRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
S F + +++ NQ P V + R+ S+++SWS P + YE+ Y +K + +
Sbjct: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEK-ELS 479
Query: 481 SYNVR--RTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSP-EGSGNLA- 536
YN ++ +VT+ L Y+ QV+A T G G S FQT++ E ++
Sbjct: 480 EYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQE 539
Query: 537 ----VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDV--YFSKSEQLKPLKTYVD 590
+IG A G+V L+ + + +RRR +RA D +++ +K Y+D
Sbjct: 540 KLPLIIGSSAAGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYID 599
Query: 591 PHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKA 650
P TYEDPN+AV +F EI SCV ++VIGAGEFGEV G LK GK+E+ VAIKTLK+
Sbjct: 600 PFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLP-GKREIFVAIKTLKS 658
Query: 651 GYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGE 710
GYTEKQR DFL EA IMGQF H N+I LEGV++K P+MIITE+MENG+LD FLR+ DG+
Sbjct: 659 GYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQ 718
Query: 711 FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-E 769
F+V+QLVGMLRGIAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDD +
Sbjct: 719 FTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSD 778
Query: 770 ATYTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMK 828
TYT++ GGKIPIRWTAPEAI YRKFTSASDVWS+GIVMWEVM+YGERPYW+++N +V+
Sbjct: 779 PTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVIN 838
Query: 829 AINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFD 888
AI +RLP PMDCPSA++QLM+ CWQ++R RPKF IV+ LDK+IR P+SLK +A
Sbjct: 839 AIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLS 898
Query: 889 PRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIG 948
+++ L + + F TV EWLE+IKM QY E F AG+T+ + V QM +DI R+G
Sbjct: 899 SGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVG 958
Query: 949 VRLPGHQKRIAYSLLGLKDQVNTV 972
V L GHQK+I S+ ++ Q+N +
Sbjct: 959 VTLAGHQKKILNSIQVMRAQMNQI 982
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 905 bits (2338), Expect = 0.0
Identities = 478/983 (48%), Positives = 639/983 (65%), Gaps = 33/983 (3%)
Query: 15 GCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVM 73
G AL E L+D A ELGW+ HP GW+ + +M I Y VCNV
Sbjct: 7 GAALLLLPLLAAVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVF 65
Query: 74 SGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGT- 132
Q+NWLRT ++ R A RI +E+KF+VRDC+S P SCKETFNLYY E+D D T
Sbjct: 66 ESSQNNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATK 125
Query: 133 ---NFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACV 189
N+ + + K+DTIA DE D R +K+N E RS GP++R GFYLAFQD G C+
Sbjct: 126 TFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCM 185
Query: 190 ALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMH 246
+L++VRV+Y+KCP ++Q A F ET++G+++ SL G+C+ +A VP +++
Sbjct: 186 SLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPI-----KLY 240
Query: 247 CAVDGEWLVPIGQCLCQAGYEKVEDA--CQACSPGFFKFEASESPCLECPEHTLPSPEGA 304
C DGEWLVPIG+C+C+AG+E VE+ C+ C G FK + C CP ++ + EGA
Sbjct: 241 CNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGA 300
Query: 305 TSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSV 364
T+C C G++RA DP MPCT PSAP + + + L WTPP+DSGGRED+VY++
Sbjct: 301 TNCVCRNGYYRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNI 360
Query: 365 TCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT- 423
C+ C G C C +V+Y+ GLT + +SDL H YTF ++A NGV+
Sbjct: 361 ICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPF 420
Query: 424 SRSFRTASVSINQTEPPKVRLE---GRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN 480
S F + +++ NQ P V + R+ S+++SWS P + YE+ Y +K + +
Sbjct: 421 SPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEK-ELS 479
Query: 481 SYNVR--RTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSP-EGSGNLA- 536
YN ++ +VT+ L Y+ QV+A T G G S FQT++ E ++
Sbjct: 480 EYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQE 539
Query: 537 ----VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKP-LKTYVDP 591
+IG A G+V L+ + + +RR + + + + S + P +K Y+DP
Sbjct: 540 KLPLIIGSSAAGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDP 599
Query: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651
TYEDPN+AV +F EI SCV ++VIGAGEFGEV G LK GK+E+ VAIKTLK+G
Sbjct: 600 FTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLP-GKREIFVAIKTLKSG 658
Query: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711
YTEKQR DFL EA IMGQF H N+I LEGV++K P+MIITE+MENG+LD FLR+ DG+F
Sbjct: 659 YTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQF 718
Query: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EA 770
+V+QLVGMLRGIAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDD +
Sbjct: 719 TVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDP 778
Query: 771 TYTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKA 829
TYT++ GGKIPIRWTAPEAI YRKFTSASDVWS+GIVMWEVM+YGERPYW+++N +V+ A
Sbjct: 779 TYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINA 838
Query: 830 INDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDP 889
I +RLP PMDCPSA++QLM+ CWQ++R RPKF IV+ LDK+IR P+SLK +A
Sbjct: 839 IEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSS 898
Query: 890 RVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGV 949
+++ L + + F TV EWLE+IKM QY E F AG+T+ + V QM +DI R+GV
Sbjct: 899 GINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGV 958
Query: 950 RLPGHQKRIAYSLLGLKDQVNTV 972
L GHQK+I S+ ++ Q+N +
Sbjct: 959 TLAGHQKKILNSIQVMRAQMNQI 981
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 885 bits (2288), Expect = 0.0
Identities = 474/981 (48%), Positives = 634/981 (64%), Gaps = 40/981 (4%)
Query: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGD 76
L A+A E L+D A ELGW +P GW+ + ++ I Y VCNV +
Sbjct: 9 LLLASAVAAMEETLMDTRTATAELGWTANP-ASGWEEVSGYDENLNTIRTYQVCNVFEPN 67
Query: 77 QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN--- 133
Q+NWL T ++ R A RI+ E++FTVRDC+S P SCKETFNLYY E+D T
Sbjct: 68 QNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSA 127
Query: 134 -FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALL 192
+ + + K+DTIA DE DF R +K+N E RS GPLTR GFYLAFQD GAC++LL
Sbjct: 128 FWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLL 187
Query: 193 SVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP----RMHCA 248
SVRV++KKCP ++Q A FPET+ G+++ SL GTC+ P EE +++C
Sbjct: 188 SVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCI------PNAEEVDVPIKLYCN 241
Query: 249 VDGEWLVPIGQCLCQAGYEKVED-ACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
DGEW+VPIG+C C+ GYE AC+AC G FK C CP ++ E + C
Sbjct: 242 GDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPIC 301
Query: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
C G++RA DP + CT PS P + ++ + L W PP+++GGR+D+ Y++ C+
Sbjct: 302 TCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICK 361
Query: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSF 427
+C + C C+ +V + GLT V++S L H YTF ++A NGVS + F
Sbjct: 362 KCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVS---SKSPF 418
Query: 428 RTASVSIN----QTEPPKVRLEGR-STTSLSVSWSIPPPQQSR--VWKYEVTYRKKGDSN 480
VS+N Q P V + + S T S++ S P P+Q + YE+ Y +K + N
Sbjct: 419 PPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHN 477
Query: 481 SYN--VRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLA-- 536
+N + R++ + +D L P Y+VQV+A T G G S FQTL+ + +
Sbjct: 478 EFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELRE 537
Query: 537 ----VIGGVAVGVVLLLVLAGVGFFIHRRRK-NQRARQSPEDVYFSKSEQLKPLKTYVDP 591
+ G A GVV ++ L + R+R ++ A S + ++S +K Y+DP
Sbjct: 538 QLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDP 597
Query: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651
TYEDPN+AV +F EI S V ++VIGAGEFGEVYKG LK GK+E+ VAIKTLKAG
Sbjct: 598 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLP-GKREIYVAIKTLKAG 656
Query: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711
Y+EKQR DFL EA IMGQF H NIIRLEGV++K +P+MIITE+MENGALD FLR+ DG+F
Sbjct: 657 YSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQF 716
Query: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EA 770
+V+QLVGMLRGIAAGMKYLA MNYVHRDLAARNILVNSNLVCKVSDFGLSR L+DD +
Sbjct: 717 TVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP 776
Query: 771 TYTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKA 829
TYT+S GGKIP+RWTAPEAI+YRKFTSASDVWS+GIVMWEVM++GERPYW++SN +V+ A
Sbjct: 777 TYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINA 836
Query: 830 INDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDP 889
I +RLP PMDCP+A++QLM+ CWQ++R RP+FA+IV+ LDK+IR P SLKT+A
Sbjct: 837 IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITA 896
Query: 890 RVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGV 949
S L S + F TV +WL +IKM QY + F+ AG+T+++ V QMT++D+ RIG+
Sbjct: 897 VPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGI 956
Query: 950 RLPGHQKRIAYSLLGLKDQVN 970
L GHQK+I S+ ++ Q++
Sbjct: 957 TLAGHQKKILNSIHSMRVQIS 977
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 875 bits (2260), Expect = 0.0
Identities = 470/980 (47%), Positives = 626/980 (63%), Gaps = 44/980 (4%)
Query: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGD 76
L A + E L+D EL W +HP GW+ + M PI Y VCNV
Sbjct: 29 LLLPAGCRALEETLMDTKWVTSELAWTSHPES-GWEEVSGYDEAMNPIRTYQVCNVRESS 87
Query: 77 QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN--- 133
Q+NWLRT +++R + +R+++ELKFTVRDCNS P SCKETFNL+Y E+D D +
Sbjct: 88 QNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSP 147
Query: 134 -FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALL 192
+ + + K+DTIAPDE D ++N + RS GPL++ GFYLAFQD GAC++L+
Sbjct: 148 FWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLI 203
Query: 193 SVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAV---VPPGGEEPRMHCAV 249
SVR +YKKC G A FPET+ G++ SL GTC+ +AV VP +++C
Sbjct: 204 SVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPL-----KLYCNG 258
Query: 250 DGEWLVPIGQCLCQAGYEKV--EDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
DGEW+VP+G C C G+E E C+ C PG +K + E PCL CP ++ + A+ C
Sbjct: 259 DGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASIC 318
Query: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
C F+RA D A CT PS P + + + L W+ P+D GGR+D++Y+V C+
Sbjct: 319 TCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICK 378
Query: 368 QCWPESGE--CGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT-S 424
+C G C C+ +V + GLT V +S L H YTF V+A NGVSG
Sbjct: 379 KCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLP 438
Query: 425 RSFRTASVSINQTEP---PKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNS 481
+ +++ NQ P P +RL S +SL++SW+ P + YE+ Y +K + +
Sbjct: 439 PRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIA 498
Query: 482 YNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLA----- 536
V ++ SV LD L PD Y+VQV+A T G G S+ EF+T S GSG
Sbjct: 499 STVT-SQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQL 557
Query: 537 --VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQ-LKP-LKTYVDPH 592
++G G+V ++ + + R++ R + Y K +Q + P +K Y+DP
Sbjct: 558 PLIVGSATAGLVFVVAVVVIAIVCLRKQ-----RHGSDSEYTEKLQQYIAPGMKVYIDPF 612
Query: 593 TYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGY 652
TYEDPN+AV +F EI SCV ++VIGAGEFGEV +G LK G++EV VAIKTLK GY
Sbjct: 613 TYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLK-QPGRREVFVAIKTLKVGY 671
Query: 653 TEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFS 712
TE+QR DFL EA IMGQF H NIIRLEGV++K +P+MI+TE+MEN ALD FLR DG+F+
Sbjct: 672 TERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT 731
Query: 713 VLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EAT 771
V+QLVGMLRGIAAGMKYL+ MNYVHRDLAARNILVNSNLVCKVSDFGLSR LEDDP + T
Sbjct: 732 VIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPT 791
Query: 772 YTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAI 830
YT+S GGKIPIRWTAPEAI+YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+ A+
Sbjct: 792 YTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAV 851
Query: 831 NDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPR 890
+RLP PMDCP+A++QLM+ CW ++R RPKF+ IV+ LDKLIR SLK +A
Sbjct: 852 EQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSG 911
Query: 891 VSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVR 950
+S L + + F TV +WL++IKM +Y E F++AG+ + + V QMT +D+ RIGV
Sbjct: 912 MSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVT 971
Query: 951 LPGHQKRIAYSLLGLKDQVN 970
L GHQK+I S+ ++ Q+N
Sbjct: 972 LAGHQKKILSSIQDMRLQMN 991
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 814 bits (2102), Expect = 0.0
Identities = 457/976 (46%), Positives = 602/976 (61%), Gaps = 36/976 (3%)
Query: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKG-WDLMQNIMNDM-PIYMYSVCNVMSG 75
L A+ A E LL+ +L W+T P G W+ + + + + Y VC+V
Sbjct: 7 LCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRA 66
Query: 76 D-QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN- 133
Q +WLRT WV R A ++ L+FT+ +C S P SCKETF ++Y ESD D T
Sbjct: 67 PGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATAL 126
Query: 134 ---FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVA 190
+ + + K+DT+A + +T K+NV+ +GPL++ GFYLAFQD GAC+A
Sbjct: 127 TPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMA 186
Query: 191 LLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVD 250
LLS+ ++YKKC +L L FPET+ + VAG+CV AV PG P ++C D
Sbjct: 187 LLSLHLFYKKCAQLTVNLTRFPETVPRE---LVVPVAGSCVVDAVPAPG-PSPSLYCRED 242
Query: 251 GEWLV-PIGQCLCQAGYEKVED--ACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
G+W P+ C C G+E E C+AC+ G FK + E C CP ++ + G+ C
Sbjct: 243 GQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVC 302
Query: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
+C G+FRA DP PCT PPSAP + + G+ + L W+ P +SGGRED+ Y++ C
Sbjct: 303 QCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCR 362
Query: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSR-S 426
+C P G C PC + + P L V V L P YTF V A NGVS L T
Sbjct: 363 ECRP-GGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVP 421
Query: 427 FRTASVSINQTEPPKV---RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYN 483
F +V+ ++ PP V R+ S +SLS++W++P V YEV Y +KG +
Sbjct: 422 FEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSS 481
Query: 484 VR--RTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSG---NLAVI 538
VR +T L L +YLVQV+A ++ G G + H QT E G LA+I
Sbjct: 482 VRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLALI 541
Query: 539 GGVAV-GVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQL---KPLKTYVDPHTY 594
G AV GVVL+LV+ V R++ N R E Y K Q K Y+DP TY
Sbjct: 542 AGTAVVGVVLVLVVIVVAVLCLRKQSNGR-----EAEYSDKHGQYLIGHGTKVYIDPFTY 596
Query: 595 EDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTE 654
EDPN+AV +F EI S V ++VIGAGEFGEV +G LK + GKKE VAIKTLK GYTE
Sbjct: 597 EDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLK-APGKKESCVAIKTLKGGYTE 655
Query: 655 KQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL 714
+QR +FL EA IMGQF H NIIRLEGV++ P+MI+TE+MENGALD FLR DG+F+V+
Sbjct: 656 RQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVI 715
Query: 715 QLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDD-PEATYT 773
QLVGMLRGIA+GM+YLA M+YVHRDLAARNILVNSNLVCKVSDFGLSR LE++ + TYT
Sbjct: 716 QLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYT 775
Query: 774 TS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIND 832
+S GGKIPIRWTAPEAI++RKFTSASD WS+GIVMWEVM++GERPYW++SN +V+ AI
Sbjct: 776 SSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
Query: 833 GFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVS 892
+RLP P DCP++++QLM+ CWQ++R RP+F +VS LDK+IR P SLK +A + S
Sbjct: 836 DYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGAS 895
Query: 893 IRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLP 952
L F +V EWL +IKM +Y E F AAG+ + E V Q++ +D+ RIGV L
Sbjct: 896 HPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLA 955
Query: 953 GHQKRIAYSLLGLKDQ 968
GHQK+I S+ +K Q
Sbjct: 956 GHQKKILASVQHMKSQ 971
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 760 bits (1962), Expect = 0.0
Identities = 419/992 (42%), Positives = 589/992 (59%), Gaps = 44/992 (4%)
Query: 9 CFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMY 67
C ALL G A +EV+LLD A+ ELGW P GW+ + + +D PI Y
Sbjct: 20 CLALLLGPWRPGTA----EEVILLDSKASQAELGWTALP-SNGWEEISGVDEHDRPIRTY 74
Query: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
VCNV+ +QDNWL+T W+ RG +RIF+EL+FT+RDC+S PG A +CKETFN+YY E++
Sbjct: 75 QVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETE 134
Query: 128 LDYGTNFQKRLF----TKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQ 183
D G + RL KIDTIA DE D R +KLN E R +GPL+R+GF+LAFQ
Sbjct: 135 ADLGRG-RPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQ 193
Query: 184 DIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP 243
D+GACVAL+SVRVYYK+C ++GLA FP T A S +L VAGTCV H+ PG P
Sbjct: 194 DVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSP-P 252
Query: 244 RMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEG 303
RMHC DGEWLVP+G+C C AG+++ D C+AC PGF+K C CPEH+
Sbjct: 253 RMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENA 312
Query: 304 ATSCECEEGFFRAPQDPASMPCTRPPSAPHYL--TAVGMGAKVELRWTPPQDSGGREDIV 361
+T C C++ + R+P DP S CTRPPSAP L + + LRW PP DSGGR D+
Sbjct: 313 STFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVT 372
Query: 362 YSVTCEQCWPE--SGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVS 419
YS+ C +C E +G C PC V + GL + T+ L P YT V A NGVS
Sbjct: 373 YSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVS 432
Query: 420 GLVTSRSFRTASVSINQT-----EPPKVRLEGRSTTSLSVSWSIPPPQQS---RVWKYEV 471
G + A V+++ E ++R + S+S+SW P P + +YE+
Sbjct: 433 GPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEI 492
Query: 472 TYRKKGDSN-SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQ----EGQGAGSKVHEFQT 526
Y +KG S +Y++ +T +VT+ +L P T Y+ Q++A + E Q + E QT
Sbjct: 493 RYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSI-EVQT 551
Query: 527 LSPEGSGNLAVIGGVAVGVVLLLVLAGVG-----FFIHRRR----KNQRARQSPEDVYFS 577
L SG+ + V VV + L +G I RR K E++YF
Sbjct: 552 LGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFH 611
Query: 578 KSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSG 637
+ +T++DP + D QAV F E+ VT ++ +G G FGE+ G L+ G
Sbjct: 612 FKVPTR--RTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLP-G 668
Query: 638 KKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMEN 697
++E+ VA+ L+ ++ QR+ FL EA +GQF H +I+RLEGV+++ +MI+TEYM +
Sbjct: 669 RQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSH 728
Query: 698 GALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSD 757
GALD FLR +G+ QL+G+L G+A+ MKYL+ M YVHR LAAR++LV+S+LVCK+S
Sbjct: 729 GALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISG 788
Query: 758 FGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERP 817
FG R D EA YTT G+ P W APE + + F+SASDVWSFGI+MWEVM +GERP
Sbjct: 789 FG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERP 846
Query: 818 YWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRA 877
YW++S +V+KA+ DGFRLP P +CP+ +++LM+ CWQ++ RP+F+ I SIL K+++
Sbjct: 847 YWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQD 906
Query: 878 PDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVV 937
P+ K PR L + S F +V WLE++ + +Y + F AAGY ++E V
Sbjct: 907 PEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVA 966
Query: 938 QMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQV 969
+MT D+ +G+ L H++ + + L+ +V
Sbjct: 967 EMTAQDLVSLGISLAEHREALLSGISALQARV 998
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 672 bits (1735), Expect = 0.0
Identities = 393/1018 (38%), Positives = 573/1018 (56%), Gaps = 77/1018 (7%)
Query: 13 LWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDMP--IYMYSVC 70
LW L ++ A E VLLD E+GWLT+P G GWD + ++++D + C
Sbjct: 20 LWVLLLVSSVLAL--EEVLLDTTGETSEIGWLTYPPG-GWDEV-SVLDDQRRLTRTFEAC 75
Query: 71 NVMSGD----QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAES 126
+V QDNWL+T++V R A+R I L F+VR C+S +C+ETF LYY ++
Sbjct: 76 HVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQA 135
Query: 127 DL----DYGTNFQKRLFTKIDTIAPDEITVSSDFEARH------------------VKLN 164
+ D +++ + +TK+DTIA DE SS + ++LN
Sbjct: 136 EEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLN 195
Query: 165 VEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIA-GSDAPSL 223
V+ERS GPLT++GFY+AFQD GAC+AL++VR++ CP +L+ A FPET A G+ SL
Sbjct: 196 VKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASL 255
Query: 224 ATVAGTCVDHAVVPP-------GGEEPRMHCAVDGEWLVPIGQCLCQAGYEKV--EDACQ 274
GTCV HA GG PR+HC +G+W+V +G C CQ GY+ + ACQ
Sbjct: 256 VAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQ 315
Query: 275 ACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHY 334
AC G +K A +PC CP + A C C EGF+RA DP PCT PPSAP
Sbjct: 316 ACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQE 375
Query: 335 LTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCW----PESG---ECGPCEASVRYSE 387
L G+ + L W P++ GGR D++++V C++C P SG C C V +
Sbjct: 376 LWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDP 435
Query: 388 PPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTA-SVSINQTEP---PKVR 443
GLT + V V L H+ Y V+A NGVS L A +VS + P P V
Sbjct: 436 RQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVH 495
Query: 444 LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRT-EGFSVTLDDLAPDTT 502
R++ S++VSW P + Y++ Y + + S++ T E + T+ L+P
Sbjct: 496 QVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHI 555
Query: 503 YLVQVQALTQEGQGA-GSKVHEFQTLSPEGS------GNLAVIGGVAVGVVLLLVLAGVG 555
Y QV+A T G G G KV+ FQTL P+G L+++ G +G + L+LA +
Sbjct: 556 YGFQVRARTAAGHGPYGGKVY-FQTL-PQGELSSQLPERLSLVIGSILGALAFLLLAAIT 613
Query: 556 FFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTR 615
++ +R E + S L +K Y+DP TYEDP QA+ + E+ P+ +
Sbjct: 614 VLAVVFQRKRRGTGYTEQLQQYSSPGLG-VKYYIDPSTYEDPCQAIRELAREVDPAYIKI 672
Query: 616 QKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNI 675
++VIG G FGEV +G L+ G++E VAI+ L AG E ++ FLG A ++GQF H NI
Sbjct: 673 EEVIGTGSFGEVRQGRLQPR-GRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNI 731
Query: 676 IRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLANMNY 735
+RLEGV++K +P+M++TE+ME G LD FLR+++G+FS LQLV M RG+AA M+YL++ +
Sbjct: 732 LRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAF 791
Query: 736 VHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYRKFT 795
VHR L+A ++LVNS+LVCKV+ G ++ G +RW APE I++ K T
Sbjct: 792 VHRSLSAHSVLVNSHLVCKVARLG------------HSPQGPSCLLRWAAPEVIAHGKHT 839
Query: 796 SASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQ 855
++SDVWSFGI+MWEVM+YGERPYW++S EV+ AI FRLP P CP ++ LM+ WQ
Sbjct: 840 TSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQ 899
Query: 856 QERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEGVPFRTVSEWLES 915
++RARRP F +V+ DK+IR PD+L+ D R S L + + + WL +
Sbjct: 900 KDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSA 959
Query: 916 IKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLLGLKDQVNTVG 973
I ++ Y ++F G V Q++ +D+ +G+ L GHQK++ + + L+ + G
Sbjct: 960 IGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQG 1017
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 468 bits (1203), Expect = e-131
Identities = 239/509 (46%), Positives = 321/509 (63%), Gaps = 12/509 (2%)
Query: 28 EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGDQDNWLRTNWV 86
EV LLD GELGW+++P GW+ + + PI Y VCNVM Q+NWLRTNWV
Sbjct: 29 EVNLLDSKTIQGELGWISYP-SHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWV 87
Query: 87 YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146
R A++I++ELKFT+RDCNS P +CKETFNLYY ESD D+G F++ FTKIDTIA
Sbjct: 88 PRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIA 147
Query: 147 PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206
DE D R +KLN E R VGP+ +KGFYLAFQD+GACVAL+SVRVY+KKCP ++
Sbjct: 148 ADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK 207
Query: 207 GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266
LA FP+T+ D+ SL V G+CV+++ + PRM+C+ +GEWLVPIG+C C AGY
Sbjct: 208 NLAMFPDTVP-MDSQSLVEVRGSCVNNS---KEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263
Query: 267 EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326
E+ CQAC PGF+K C +CP H+ +G+ +C CE +FRA +DP SM CT
Sbjct: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
Query: 327 RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
RPPS+P + + V L W+ P D+GGR+D+ +++ C++C +C PC +VR+
Sbjct: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
Query: 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT-SRSFRTASVSINQTEPPKV--- 442
GLT T+VTV+DL H NYTF ++A NGVS L + R F S++ NQ P V
Sbjct: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
Query: 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVT-YRKKGDSNSYNVRRTEGFSVTLDDLAPDT 501
+ + S S+S+SW P + YEV Y K+ SY + R G +VT+ L PDT
Sbjct: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
Query: 502 TYLVQVQALTQEGQGAGSKVHEFQTLSPE 530
Y+ Q++A T G G S+ EF+T SP+
Sbjct: 504 IYVFQIRARTAAGYGTNSRKFEFET-SPD 531
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 414 bits (1063), Expect = e-115
Identities = 209/436 (47%), Positives = 272/436 (62%), Gaps = 10/436 (2%)
Query: 13 LWGCALAAAAA----AQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMND-MPIYMY 67
LW AAAAA A EV LLD + G+ GWLT+P GWD + + PI+ Y
Sbjct: 12 LWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYP-AHGWDSINEVDESFQPIHTY 70
Query: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
VCNVMS +Q+NWLRT+WV R A R++ E+KFT+RDCNS PG +CKETFNLYY ESD
Sbjct: 71 QVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESD 130
Query: 128 LDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGA 187
D G + Q+ F KIDTIA DE +D R +KLN E RSVGPL+++GFYLAFQDIGA
Sbjct: 131 RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGA 190
Query: 188 CVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHC 247
C+A+LS+R+YYKKCP +++ LA F E + G+D+ SL V G CV H+ + P+M+C
Sbjct: 191 CLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHS---EERDTPKMYC 247
Query: 248 AVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
+ +GEWLVPIG+C+C AGYE+ DAC AC GF+K + C CP H+ + A +C
Sbjct: 248 SAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQAC 307
Query: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
C+ ++RA DP S CTRPPSAP L + G V L W PP D GGR DI Y+ C
Sbjct: 308 HCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCR 367
Query: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSF 427
+C C C + R+ L + S+ V++L HMNY+F +EA NGVS L +
Sbjct: 368 RCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDL-SPEPR 426
Query: 428 RTASVSINQTEPPKVR 443
R A V+I + + R
Sbjct: 427 RAAVVNITTNQAGRRR 442
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 273 bits (697), Expect = 7e-73
Identities = 140/271 (51%), Positives = 179/271 (66%), Gaps = 12/271 (4%)
Query: 9 CFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNI-MNDMPIYMY 67
C ALL G A +EV+LLD A+ ELGW P GW+ + + +D PI Y
Sbjct: 20 CLALLLGPWRPGTA----EEVILLDSKASQAELGWTALP-SNGWEEISGVDEHDRPIRTY 74
Query: 68 SVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESD 127
VCNV+ +QDNWL+T W+ RG +RIF+EL+FT+RDC+S PG A +CKETFN+YY E++
Sbjct: 75 QVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETE 134
Query: 128 LDYGTNFQKRLF----TKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQ 183
D G + RL KIDTIA DE D R +KLN E R +GPL+R+GF+LAFQ
Sbjct: 135 ADLGRG-RPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQ 193
Query: 184 DIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP 243
D+GACVAL+SVRVYYK+C ++GLA FP T A S +L VAGTCV H+ P G P
Sbjct: 194 DVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEP-GSPP 252
Query: 244 RMHCAVDGEWLVPIGQCLCQAGYEKVEDACQ 274
RMHC DGEWLVP+G+C C AG+++ D C+
Sbjct: 253 RMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|31657140 insulin receptor-related receptor precursor [Homo
sapiens]
Length = 1297
Score = 244 bits (623), Expect = 3e-64
Identities = 158/457 (34%), Positives = 241/457 (52%), Gaps = 43/457 (9%)
Query: 439 PPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSY----NVRRTEGFSVTL 494
P KV E S S+ + W PP + KYE+ YR+ G+ + +R + V L
Sbjct: 819 PGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHL 878
Query: 495 DDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPE---GSGNLAVIGGVAVGVVLLLVL 551
L P Y +V+A + G G+ + F L PE G ++ VG+ LL+VL
Sbjct: 879 A-LLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVL 937
Query: 552 AGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPS 611
A +GFF ++R N+ S YFS S+ YV P +E P + +
Sbjct: 938 AALGFFYGKKR-NRTLYASVNPEYFSASDM------YV-PDEWEVPREQI---------- 979
Query: 612 CVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQF 670
+ R+ +G G FG VY+G+ + +G++ PVA+KT+ + ++ ++FL EA +M F
Sbjct: 980 SIIRE--LGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAF 1037
Query: 671 SHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF---------SVLQLVGMLR 721
H+++RL GV+S+ +P ++I E M G L LR E ++ +++ M
Sbjct: 1038 KCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAG 1097
Query: 722 GIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK--I 779
IA GM YLA +VHRDLAARN +V+ + K+ DFG++R D E Y GGK +
Sbjct: 1098 EIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTR---DVYETDYYRKGGKGLL 1154
Query: 780 PIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTP 839
P+RW APE++ FT+ SDVWSFG+V+WE++T E+PY LSN +V+K + DG L
Sbjct: 1155 PVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEL 1214
Query: 840 MDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIR 876
CP + +LM +CWQ RP F I+ + + +R
Sbjct: 1215 EGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELR 1251
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 228 bits (582), Expect = 2e-59
Identities = 122/286 (42%), Positives = 178/286 (62%), Gaps = 13/286 (4%)
Query: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQ 656
P + K EI + +K +GAG+FGEV+ ++ K VA+KT+K G +
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWM-----ATYNKHTKVAVKTMKPGSMSVE 300
Query: 657 RVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL-Q 715
FL EA +M H +++L V++K +P+ IITE+M G+L FL+ +G L +
Sbjct: 301 A--FLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLPK 357
Query: 716 LVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTT- 774
L+ IA GM ++ NY+HRDL A NILV+++LVCK++DFGL+RV+ED+ YT
Sbjct: 358 LIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNE---YTAR 414
Query: 775 SGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGF 834
G K PI+WTAPEAI++ FT SDVWSFGI++ E++TYG PY +SN EV++A+ G+
Sbjct: 415 EGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGY 474
Query: 835 RLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDS 880
R+P P +CP +Y +MM+CW+ RP F I S+LD A +S
Sbjct: 475 RMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATES 520
>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-2 precursor [Homo sapiens]
Length = 1292
Score = 226 bits (577), Expect = 6e-59
Identities = 132/366 (36%), Positives = 202/366 (55%), Gaps = 15/366 (4%)
Query: 537 VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYED 596
+I +G + +LV+ G+ F ++ RRK+ + +++ F ++E ++PL +
Sbjct: 652 LIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRR--FLETELVEPLTP-----SGTA 704
Query: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQ 656
PNQA L+ E + R KV+G+G FG VYKG+ ++PVAIK L K
Sbjct: 705 PNQAQLRILKETE---LKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKA 761
Query: 657 RVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQL 716
V+F+ EA IM H +++RL GV + ++T+ M +G L +++ E L
Sbjct: 762 NVEFMDEALIMASMDHPHLVRLLGVCLS-PTIQLVTQLMPHGCLLEYVHEHKDNIGSQLL 820
Query: 717 VGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSG 776
+ IA GM YL VHRDLAARN+LV S K++DFGL+R+LE D E Y G
Sbjct: 821 LNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGD-EKEYNADG 879
Query: 777 GKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRL 836
GK+PI+W A E I YRKFT SDVWS+G+ +WE+MT+G +PY + E+ + G RL
Sbjct: 880 GKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERL 939
Query: 837 PTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLP 896
P P C +Y +M++CW + RPKF ++ + ++ R P + D ++LP
Sbjct: 940 PQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDD---RMKLP 996
Query: 897 STSGSE 902
S + S+
Sbjct: 997 SPNDSK 1002
>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-1 precursor [Homo sapiens]
Length = 1308
Score = 226 bits (577), Expect = 6e-59
Identities = 132/366 (36%), Positives = 202/366 (55%), Gaps = 15/366 (4%)
Query: 537 VIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYED 596
+I +G + +LV+ G+ F ++ RRK+ + +++ F ++E ++PL +
Sbjct: 652 LIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRR--FLETELVEPLTP-----SGTA 704
Query: 597 PNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQ 656
PNQA L+ E + R KV+G+G FG VYKG+ ++PVAIK L K
Sbjct: 705 PNQAQLRILKETE---LKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKA 761
Query: 657 RVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQL 716
V+F+ EA IM H +++RL GV + ++T+ M +G L +++ E L
Sbjct: 762 NVEFMDEALIMASMDHPHLVRLLGVCLS-PTIQLVTQLMPHGCLLEYVHEHKDNIGSQLL 820
Query: 717 VGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSG 776
+ IA GM YL VHRDLAARN+LV S K++DFGL+R+LE D E Y G
Sbjct: 821 LNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGD-EKEYNADG 879
Query: 777 GKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRL 836
GK+PI+W A E I YRKFT SDVWS+G+ +WE+MT+G +PY + E+ + G RL
Sbjct: 880 GKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERL 939
Query: 837 PTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLP 896
P P C +Y +M++CW + RPKF ++ + ++ R P + D ++LP
Sbjct: 940 PQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDD---RMKLP 996
Query: 897 STSGSE 902
S + S+
Sbjct: 997 SPNDSK 1002
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 226 bits (576), Expect = 8e-59
Identities = 148/456 (32%), Positives = 230/456 (50%), Gaps = 51/456 (11%)
Query: 439 PPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFS---VTLD 495
P V E R S+ + W P + YE+ Y + + V R E L+
Sbjct: 835 PGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLN 894
Query: 496 DLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLAGVG 555
L P Y ++QA + G G+ + F + G N + +A+ V +LL++ G+
Sbjct: 895 RLNPGN-YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLI-IALPVAVLLIVGGLV 952
Query: 556 FFI---HRRRKNQR-------ARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFT 605
+ HR+R N R A +PE YFS ++ P +
Sbjct: 953 IMLYVFHRKRNNSRLGNGVLYASVNPE--YFSAADVYVPDEW------------------ 992
Query: 606 TEIHPSCVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRVDFLGEA 664
E+ +T + +G G FG VY+G+ K + E VAIKT+ + ++R++FL EA
Sbjct: 993 -EVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEA 1051
Query: 665 GIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF---------SVLQ 715
+M +F+ H+++RL GV+S+ +P ++I E M G L +LR E S+ +
Sbjct: 1052 SVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSK 1111
Query: 716 LVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTS 775
++ M IA GM YL +VHRDLAARN +V + K+ DFG++R D E Y
Sbjct: 1112 MIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR---DIYETDYYRK 1168
Query: 776 GGK--IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDG 833
GGK +P+RW +PE++ FT+ SDVWSFG+V+WE+ T E+PY LSN +V++ + +G
Sbjct: 1169 GGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEG 1228
Query: 834 FRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVS 869
L P +CP +++LM CWQ RP F +I+S
Sbjct: 1229 GLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIIS 1264
>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform B [Homo sapiens]
Length = 491
Score = 224 bits (571), Expect = 3e-58
Identities = 118/275 (42%), Positives = 173/275 (62%), Gaps = 12/275 (4%)
Query: 607 EIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGI 666
EI + K +GAG+FGEV+ G S+ VA+KTLK G Q FL EA +
Sbjct: 220 EIPRESIKLVKRLGAGQFGEVWMGYYNNST-----KVAVKTLKPGTMSVQA--FLEEANL 272
Query: 667 MGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL-QLVGMLRGIAA 725
M H ++RL V+++ +P+ IITEYM G+L FL+ +G +L +L+ IA
Sbjct: 273 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 332
Query: 726 GMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTT-SGGKIPIRWT 784
GM Y+ NY+HRDL A N+LV+ +L+CK++DFGL+RV+ED+ YT G K PI+WT
Sbjct: 333 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKWT 389
Query: 785 APEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPS 844
APEAI++ FT SDVWSFGI+++E++TYG+ PY +N +VM A++ G+R+P +CP
Sbjct: 390 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPD 449
Query: 845 AIYQLMMQCWQQERARRPKFADIVSILDKLIRAPD 879
+Y +M CW+++ RP F + S+LD A +
Sbjct: 450 ELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 484
>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
isoform A [Homo sapiens]
Length = 512
Score = 224 bits (571), Expect = 3e-58
Identities = 118/275 (42%), Positives = 173/275 (62%), Gaps = 12/275 (4%)
Query: 607 EIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGI 666
EI + K +GAG+FGEV+ G S+ VA+KTLK G Q FL EA +
Sbjct: 241 EIPRESIKLVKRLGAGQFGEVWMGYYNNST-----KVAVKTLKPGTMSVQA--FLEEANL 293
Query: 667 MGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL-QLVGMLRGIAA 725
M H ++RL V+++ +P+ IITEYM G+L FL+ +G +L +L+ IA
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAE 353
Query: 726 GMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTT-SGGKIPIRWT 784
GM Y+ NY+HRDL A N+LV+ +L+CK++DFGL+RV+ED+ YT G K PI+WT
Sbjct: 354 GMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKWT 410
Query: 785 APEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPS 844
APEAI++ FT SDVWSFGI+++E++TYG+ PY +N +VM A++ G+R+P +CP
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPD 470
Query: 845 AIYQLMMQCWQQERARRPKFADIVSILDKLIRAPD 879
+Y +M CW+++ RP F + S+LD A +
Sbjct: 471 ELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATE 505
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 221 bits (564), Expect = 2e-57
Identities = 174/622 (27%), Positives = 292/622 (46%), Gaps = 64/622 (10%)
Query: 282 KFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMG 341
++E S C CP+ + E EE FR + P T+ G G
Sbjct: 701 EYEDSAGECCSCPK-----TDSQILKELEESSFRKTFEDYLHNVVFVPRK----TSSGTG 751
Query: 342 AKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSD 401
A+ + G ++ +V +P + + + + + S+ +S
Sbjct: 752 AEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISG 811
Query: 402 LEPHMNYTFTVEARN--------GVSGLVTSRSFRTASVSINQTEPPKVRLEGRSTTSLS 453
L Y ++A N V+ V++R+ A + P V E +
Sbjct: 812 LRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKAD-DIVGP--VTHEIFENNVVH 868
Query: 454 VSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVT----LDDLAPDTTYLVQVQA 509
+ W P + YEV+YR+ GD + + F++ L L+P Y V+++A
Sbjct: 869 LMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGN-YSVRIRA 927
Query: 510 LTQEGQGAGSK-VHEFQTLSPEGSGNLA--VIGGVAVGVVLLLVLAGVGFFIHRRRKNQR 566
+ G G+ ++ + + T + N+A +IG + + +V+ + F+ +R+ +
Sbjct: 928 TSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGP 987
Query: 567 -----ARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGA 621
A +PE Y S S+ P YV P++ E+ +T + +G
Sbjct: 988 LGPLYASSNPE--YLSASDVF-PCSVYV-------PDE------WEVSREKITLLRELGQ 1031
Query: 622 GEFGEVYKGMLKTS-SGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEG 680
G FG VY+G + G+ E VA+KT+ + ++R++FL EA +M F+ H+++RL G
Sbjct: 1032 GSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLG 1091
Query: 681 VISKYKPMMIITEYMENGALDKFLREKDGEF---------SVLQLVGMLRGIAAGMKYLA 731
V+SK +P +++ E M +G L +LR E ++ +++ M IA GM YL
Sbjct: 1092 VVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLN 1151
Query: 732 NMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK--IPIRWTAPEAI 789
+VHRDLAARN +V + K+ DFG++R D E Y GGK +P+RW APE++
Sbjct: 1152 AKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMAPESL 1208
Query: 790 SYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQL 849
FT++SD+WSFG+V+WE+ + E+PY LSN +V+K + DG L P +CP + L
Sbjct: 1209 KDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDL 1268
Query: 850 MMQCWQQERARRPKFADIVSIL 871
M CWQ RP F +IV++L
Sbjct: 1269 MRMCWQFNPKMRPTFLEIVNLL 1290
>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (563), Expect = 3e-57
Identities = 137/321 (42%), Positives = 192/321 (59%), Gaps = 17/321 (5%)
Query: 555 GFFIHRRRKNQRARQSPEDVYFSK-SEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCV 613
GF+I R + +Q Y+SK ++ L T V P T + Q + K EI +
Sbjct: 214 GFYITSRTQFNSLQQLV--AYYSKHADGLCHRLTTVCP-TSKPQTQGLAKDAWEIPRESL 270
Query: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673
+ +G G FGEV+ G T +G V AIKTLK G + FL EA +M + H
Sbjct: 271 RLEVKLGQGCFGEVWMG---TWNGTTRV--AIKTLKPGTMSPEA--FLQEAQVMKKLRHE 323
Query: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL-QLVGMLRGIAAGMKYLAN 732
+++L V+S+ +P+ I+TEYM G+L FL+ + G++ L QLV M IA+GM Y+
Sbjct: 324 KLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER 382
Query: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTT-SGGKIPIRWTAPEAISY 791
MNYVHRDL A NILV NLVCKV+DFGL+R++ED+ YT G K PI+WTAPEA Y
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALY 439
Query: 792 RKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMM 851
+FT SDVWSFGI++ E+ T G PY + N EV+ + G+R+P P +CP +++ LM
Sbjct: 440 GRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499
Query: 852 QCWQQERARRPKFADIVSILD 872
QCW++E RP F + + L+
Sbjct: 500 QCWRKEPEERPTFEYLQAFLE 520
>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
sapiens]
Length = 536
Score = 221 bits (563), Expect = 3e-57
Identities = 137/321 (42%), Positives = 192/321 (59%), Gaps = 17/321 (5%)
Query: 555 GFFIHRRRKNQRARQSPEDVYFSK-SEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCV 613
GF+I R + +Q Y+SK ++ L T V P T + Q + K EI +
Sbjct: 214 GFYITSRTQFNSLQQLV--AYYSKHADGLCHRLTTVCP-TSKPQTQGLAKDAWEIPRESL 270
Query: 614 TRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHH 673
+ +G G FGEV+ G T +G V AIKTLK G + FL EA +M + H
Sbjct: 271 RLEVKLGQGCFGEVWMG---TWNGTTRV--AIKTLKPGTMSPEA--FLQEAQVMKKLRHE 323
Query: 674 NIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVL-QLVGMLRGIAAGMKYLAN 732
+++L V+S+ +P+ I+TEYM G+L FL+ + G++ L QLV M IA+GM Y+
Sbjct: 324 KLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER 382
Query: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTT-SGGKIPIRWTAPEAISY 791
MNYVHRDL A NILV NLVCKV+DFGL+R++ED+ YT G K PI+WTAPEA Y
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---YTARQGAKFPIKWTAPEAALY 439
Query: 792 RKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMM 851
+FT SDVWSFGI++ E+ T G PY + N EV+ + G+R+P P +CP +++ LM
Sbjct: 440 GRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMC 499
Query: 852 QCWQQERARRPKFADIVSILD 872
QCW++E RP F + + L+
Sbjct: 500 QCWRKEPEERPTFEYLQAFLE 520
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 219 bits (559), Expect = 8e-57
Identities = 143/440 (32%), Positives = 233/440 (52%), Gaps = 44/440 (10%)
Query: 456 WSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVT----LDDLAPDTTYLVQVQALT 511
W P + YEV+YR+ GD + + F++ L L+P Y V+++A +
Sbjct: 859 WQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGN-YSVRIRATS 917
Query: 512 QEGQGAGSK-VHEFQTLSPEGSGNLA--VIGGVAVGVVLLLVLAGVGFFIHRRRKNQR-- 566
G G+ ++ + + T + N+A +IG + + +V+ + F+ +R+ +
Sbjct: 918 LAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLG 977
Query: 567 ---ARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGE 623
A +PE Y S S+ P YV P++ E+ +T + +G G
Sbjct: 978 PLYASSNPE--YLSASDVF-PCSVYV-------PDE------WEVSREKITLLRELGQGS 1021
Query: 624 FGEVYKGMLKTS-SGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVI 682
FG VY+G + G+ E VA+KT+ + ++R++FL EA +M F+ H+++RL GV+
Sbjct: 1022 FGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV 1081
Query: 683 SKYKPMMIITEYMENGALDKFLREKDGEF---------SVLQLVGMLRGIAAGMKYLANM 733
SK +P +++ E M +G L +LR E ++ +++ M IA GM YL
Sbjct: 1082 SKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK 1141
Query: 734 NYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK--IPIRWTAPEAISY 791
+VHRDLAARN +V + K+ DFG++R D E Y GGK +P+RW APE++
Sbjct: 1142 KFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMAPESLKD 1198
Query: 792 RKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMM 851
FT++SD+WSFG+V+WE+ + E+PY LSN +V+K + DG L P +CP + LM
Sbjct: 1199 GVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMR 1258
Query: 852 QCWQQERARRPKFADIVSIL 871
CWQ RP F +IV++L
Sbjct: 1259 MCWQFNPKMRPTFLEIVNLL 1278
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,013,430
Number of Sequences: 37866
Number of extensions: 1955183
Number of successful extensions: 8434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 597
Number of HSP's successfully gapped in prelim test: 389
Number of HSP's that attempted gapping in prelim test: 5201
Number of HSP's gapped (non-prelim): 2066
length of query: 976
length of database: 18,247,518
effective HSP length: 112
effective length of query: 864
effective length of database: 14,006,526
effective search space: 12101638464
effective search space used: 12101638464
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.