Guide to the Human Genome
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Search of human proteins with 122937492

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937492 SET domain containing 5 [Homo sapiens]
         (1442 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937492 SET domain containing 5 [Homo sapiens]                  2910   0.0  
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...   585   e-166
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...   585   e-166
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    66   2e-10
gi|197313748 SET domain containing 2 [Homo sapiens]                    65   4e-10
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            64   1e-09
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        63   2e-09
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]          62   4e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    59   3e-08
gi|91982772 mucin 17 [Homo sapiens]                                    59   3e-08
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]            58   6e-08
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             58   6e-08
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    57   1e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             57   1e-07
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    57   2e-07
gi|55741677 SET domain containing 1A [Homo sapiens]                    57   2e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    56   2e-07
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]            56   3e-07
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]            55   4e-07
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        55   5e-07
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    55   5e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    54   8e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    54   1e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    54   1e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     54   1e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     54   1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   3e-06
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  52   3e-06
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          52   4e-06
gi|161016767 mucin 21 [Homo sapiens]                                   52   4e-06

>gi|122937492 SET domain containing 5 [Homo sapiens]
          Length = 1442

 Score = 2910 bits (7545), Expect = 0.0
 Identities = 1442/1442 (100%), Positives = 1442/1442 (100%)

Query: 1    MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYAT 60
            MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYAT
Sbjct: 1    MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCRGLPYAT 60

Query: 61   IIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRL 120
            IIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRL
Sbjct: 61   IIPRSDLNGLPSPVEERCGDSPNSEGETVPTWCPCGLSQDGFLLNCDKCRGMSRGKVIRL 120

Query: 121  HRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGR 180
            HRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGR
Sbjct: 121  HRRKQDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLTVRRTKPKKRKKSPEKGR 180

Query: 181  AAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSS 240
            AAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSS
Sbjct: 181  AAPKTKKIKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSS 240

Query: 241  KEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIE 300
            KEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIE
Sbjct: 241  KEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIE 300

Query: 301  YRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEV 360
            YRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEV
Sbjct: 301  YRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEV 360

Query: 361  RHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNA 420
            RHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNA
Sbjct: 361  RHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRNCPIQKRNPNA 420

Query: 421  TELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHE 480
            TELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHE
Sbjct: 421  TELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHE 480

Query: 481  EVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSN 540
            EVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSN
Sbjct: 481  EVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSN 540

Query: 541  SDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEK 600
            SDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEK
Sbjct: 541  SDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEK 600

Query: 601  LVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPT 660
            LVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPT
Sbjct: 601  LVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPT 660

Query: 661  EAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVE 720
            EAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVE
Sbjct: 661  EAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVE 720

Query: 721  CPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSC 780
            CPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSC
Sbjct: 721  CPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSC 780

Query: 781  KKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLM 840
            KKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLM
Sbjct: 781  KKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLM 840

Query: 841  EQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASR 900
            EQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASR
Sbjct: 841  EQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASR 900

Query: 901  CNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPS 960
            CNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPS
Sbjct: 901  CNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPS 960

Query: 961  RSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS 1020
            RSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS
Sbjct: 961  RSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCS 1020

Query: 1021 PAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKE 1080
            PAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKE
Sbjct: 1021 PAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKE 1080

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL
Sbjct: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT 1200
            EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT
Sbjct: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT 1200

Query: 1201 WESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS 1260
            WESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS
Sbjct: 1201 WESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS 1260

Query: 1261 PFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGY 1320
            PFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGY
Sbjct: 1261 PFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGY 1320

Query: 1321 FSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRS 1380
            FSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRS
Sbjct: 1321 FSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRS 1380

Query: 1381 SLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTG 1440
            SLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTG
Sbjct: 1381 SLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTG 1440

Query: 1441 LS 1442
            LS
Sbjct: 1441 LS 1442


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score =  585 bits (1508), Expect = e-166
 Identities = 518/1665 (31%), Positives = 750/1665 (45%), Gaps = 347/1665 (20%)

Query: 1    MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCR---GLP 57
            MSI IPLGV T++TSY +MAAGS+PESVEASP V EKS    H   T+  H      GLP
Sbjct: 1    MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60

Query: 58   YA-------------------TIIPRSDLNGLPSPVEERCGD----SPNSEGE--TVPTW 92
            YA                    +I ++++    +P  +        S + +G   T  T 
Sbjct: 61   YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120

Query: 93   CPCGLSQD-GFLLNCDKC---------------------------RGMSRGKVIRLHRRK 124
            C CG + D G+++ CDKC                           R + + + + L RRK
Sbjct: 121  CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180

Query: 125  QDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLT---VRRTKPKKRKKSPEKGRA 181
            ++N+S GD+SATES DE       LYTA QHTPTSITLT   V +   K+RKKS EK + 
Sbjct: 181  RENMSDGDTSATESGDEV---PVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQH 237

Query: 182  APKTKK-----------IKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQ 230
              K KK           +K S  E     + +  GWE +I+ W D+YEEA  NQYS  VQ
Sbjct: 238  ISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQ 297

Query: 231  NALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAAR 290
               ++        +G       +NK++L  NN +    ++      + +QK++KIL++A+
Sbjct: 298  REAQRIALR----LGNGNDKKEMNKSDLNTNNLLFKPPVE------SHIQKNKKILKSAK 347

Query: 291  DLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFI 350
            DL  D LIIEYRGK MLR+QFE NG+FFK+PYPFVLFYSKF+G+EMCVDARTFGN+ARFI
Sbjct: 348  DLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFI 407

Query: 351  RRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRN 410
            RRSCTPNAEVRH I DG IHL IY++ +I K  E+TIAFD++Y NC YKVDCAC K N  
Sbjct: 408  RRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPE 467

Query: 411  CPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARR-----KELEMEQQN---EASEENN 462
            CP+ KR+  + E             G ETRR+K ++     KE + + QN   +     N
Sbjct: 468  CPVLKRSSESMENI---------NSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTN 518

Query: 463  DQQSQEV------PEKVTVSSDHEE--VDNPEEKPEEEKEEVIDDQENLAHSRR--TRED 512
              +S E       P +++VS++ E   +D+ EEK     E  ++ +E +A  +R  TRE+
Sbjct: 519  KMKSPETKQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREE 578

Query: 513  RKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVS 572
            RK+EAI+ AF  LEKR+KRR+Q LE+         +T++T    E KTE  ++++ +   
Sbjct: 579  RKMEAILQAFARLEKREKRREQALER--------ISTAKT----EVKTECKDTQIVSDAE 626

Query: 573  NVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKR 632
             +                    + A E+   KP PAK +R + +   SR RT   Q+ +R
Sbjct: 627  VIQ-------------------EQAKEENASKPTPAKVNRTKQRKSFSRSRTHIGQQRRR 667

Query: 633  QKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVS----ITGSH 688
             +        +S  +  +  S  +    E  S  +  EN  LT    T  +    IT + 
Sbjct: 668  HRT-------VSMCSDIQPSSPDI----EVTSQQNDIENTVLTIEPETETALAEIITETE 716

Query: 689  V---NRAASKYPKTKKYLVTEWLNDKAEKQECPV----ECPLRITTDPTVLATTLNMLPG 741
            V   N+  +KYPKTKK+LV EWL++K EK   P     E PLRITTDP VLAT LN LPG
Sbjct: 717  VPALNKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPG 776

Query: 742  LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEE---GMTQTSS 798
            L +SP + +TPKHYIRF SPF+ E+RRR    +    SCKKRW+KQALEE    +    +
Sbjct: 777  LTYSPHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFN 836

Query: 799  VPQETRTQHLYQSNENSSSSSICKDNA---DLLSPLKKWKSRYLMEQNVTK--------- 846
             P + R++    + EN S   +  D+    DL +PLKK +   L++   ++         
Sbjct: 837  SPCQERSRSPAVNGENKSPL-LLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPY 895

Query: 847  ----------------------------------LLRPLSPVTPPPPNSGSKSPQLATPG 872
                                              +  P++PVTP  P +      +++P 
Sbjct: 896  ATPTHTDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPE 955

Query: 873  SS-------HPGEEECRNGYSLMFSPV--TSLT------------TASRCNTPLQFELCH 911
            SS       +  E   R+   L   P   ++LT            T+ R  T +  +   
Sbjct: 956  SSPEIKRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPG 1015

Query: 912  RK----DLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQ 967
             K    DL L     LD+     A   +L    H    P+  L  T      S  G  + 
Sbjct: 1016 EKEPVSDLQLG----LDA-VEPTALHKTLETPAHDRAEPNSQLDSTH-----SGRGTMYS 1065

Query: 968  TLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGG---------Y 1018
            + V++ D   RT  N     +  +  P       G   + + K L  D           +
Sbjct: 1066 SWVKSPD---RTGVNFSVNSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVF 1122

Query: 1019 CSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEA 1078
            C+  +G  S +   +  +L  G+ +P             QNPPQ+KKVSLLEYRKR++EA
Sbjct: 1123 CTSEDGLVSGFGRTVNDNLIDGNCTP-------------QNPPQKKKVSLLEYRKRQREA 1169

Query: 1079 KENSAG-------GGGDSAQSKSKSAGAGQGSSNSVSDTGAH------------------ 1113
            +++ +             A     + G G  SSN   +   H                  
Sbjct: 1170 RKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSE 1229

Query: 1114 ------GVQGSSARTPSSPHKKFSPSHS-----SMSHLEAVSPSDSRGTSSS-------H 1155
                   V+ ++A   + P  +++ S S       S+  A+  SD R    S        
Sbjct: 1230 ETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVS 1289

Query: 1156 CRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADG 1215
            C P    SS       + +L+  G +P      +       P PT  +     D+     
Sbjct: 1290 CSPSHVQSSPSSHSNHIPQLQAKGPVPS-FSELMEDPDPENPEPTTTNECPSPDTSQNTC 1348

Query: 1216 EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ-SLLQQSSSPFRGHPTQSPGYSY 1274
            + P  +S   S G+ +  P++   ++     P+ +S  S  +  +        Q    S 
Sbjct: 1349 KSPPKMSKPGSPGSVI--PAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSN 1406

Query: 1275 RTTALRPGNPPS----HGSSESSLSSTSYSSPAHPVSTDSL--APFTGTP------GYFS 1322
               AL   +PP     + S + S    S  +  H   +  L   P + TP      GY S
Sbjct: 1407 NNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLS 1466

Query: 1323 SQPHSGNSTGSNLPRRSCPSSAASPTLQG-----PSDSPTSDSVSQSSTGTL-------- 1369
             +P S        P  S      +P  +      P+      +  Q+++GTL        
Sbjct: 1467 PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQ 1526

Query: 1370 SSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHY 1414
            SS ++ Q ++ SL S       P    S+ YQ  + SA  N Q+Y
Sbjct: 1527 SSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSA--NFQNY 1569


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score =  585 bits (1508), Expect = e-166
 Identities = 518/1665 (31%), Positives = 750/1665 (45%), Gaps = 347/1665 (20%)

Query: 1    MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCR---GLP 57
            MSI IPLGV T++TSY +MAAGS+PESVEASP V EKS    H   T+  H      GLP
Sbjct: 1    MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60

Query: 58   YA-------------------TIIPRSDLNGLPSPVEERCGD----SPNSEGE--TVPTW 92
            YA                    +I ++++    +P  +        S + +G   T  T 
Sbjct: 61   YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120

Query: 93   CPCGLSQD-GFLLNCDKC---------------------------RGMSRGKVIRLHRRK 124
            C CG + D G+++ CDKC                           R + + + + L RRK
Sbjct: 121  CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180

Query: 125  QDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLT---VRRTKPKKRKKSPEKGRA 181
            ++N+S GD+SATES DE       LYTA QHTPTSITLT   V +   K+RKKS EK + 
Sbjct: 181  RENMSDGDTSATESGDEV---PVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQH 237

Query: 182  APKTKK-----------IKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQ 230
              K KK           +K S  E     + +  GWE +I+ W D+YEEA  NQYS  VQ
Sbjct: 238  ISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQ 297

Query: 231  NALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAAR 290
               ++        +G       +NK++L  NN +    ++      + +QK++KIL++A+
Sbjct: 298  REAQRIALR----LGNGNDKKEMNKSDLNTNNLLFKPPVE------SHIQKNKKILKSAK 347

Query: 291  DLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFI 350
            DL  D LIIEYRGK MLR+QFE NG+FFK+PYPFVLFYSKF+G+EMCVDARTFGN+ARFI
Sbjct: 348  DLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFI 407

Query: 351  RRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRN 410
            RRSCTPNAEVRH I DG IHL IY++ +I K  E+TIAFD++Y NC YKVDCAC K N  
Sbjct: 408  RRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPE 467

Query: 411  CPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARR-----KELEMEQQN---EASEENN 462
            CP+ KR+  + E             G ETRR+K ++     KE + + QN   +     N
Sbjct: 468  CPVLKRSSESMENI---------NSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTN 518

Query: 463  DQQSQEV------PEKVTVSSDHEE--VDNPEEKPEEEKEEVIDDQENLAHSRR--TRED 512
              +S E       P +++VS++ E   +D+ EEK     E  ++ +E +A  +R  TRE+
Sbjct: 519  KMKSPETKQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREE 578

Query: 513  RKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVS 572
            RK+EAI+ AF  LEKR+KRR+Q LE+         +T++T    E KTE  ++++ +   
Sbjct: 579  RKMEAILQAFARLEKREKRREQALER--------ISTAKT----EVKTECKDTQIVSDAE 626

Query: 573  NVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKR 632
             +                    + A E+   KP PAK +R + +   SR RT   Q+ +R
Sbjct: 627  VIQ-------------------EQAKEENASKPTPAKVNRTKQRKSFSRSRTHIGQQRRR 667

Query: 633  QKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVS----ITGSH 688
             +        +S  +  +  S  +    E  S  +  EN  LT    T  +    IT + 
Sbjct: 668  HRT-------VSMCSDIQPSSPDI----EVTSQQNDIENTVLTIEPETETALAEIITETE 716

Query: 689  V---NRAASKYPKTKKYLVTEWLNDKAEKQECPV----ECPLRITTDPTVLATTLNMLPG 741
            V   N+  +KYPKTKK+LV EWL++K EK   P     E PLRITTDP VLAT LN LPG
Sbjct: 717  VPALNKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPG 776

Query: 742  LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEE---GMTQTSS 798
            L +SP + +TPKHYIRF SPF+ E+RRR    +    SCKKRW+KQALEE    +    +
Sbjct: 777  LTYSPHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFN 836

Query: 799  VPQETRTQHLYQSNENSSSSSICKDNA---DLLSPLKKWKSRYLMEQNVTK--------- 846
             P + R++    + EN S   +  D+    DL +PLKK +   L++   ++         
Sbjct: 837  SPCQERSRSPAVNGENKSPL-LLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPY 895

Query: 847  ----------------------------------LLRPLSPVTPPPPNSGSKSPQLATPG 872
                                              +  P++PVTP  P +      +++P 
Sbjct: 896  ATPTHTDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPE 955

Query: 873  SS-------HPGEEECRNGYSLMFSPV--TSLT------------TASRCNTPLQFELCH 911
            SS       +  E   R+   L   P   ++LT            T+ R  T +  +   
Sbjct: 956  SSPEIKRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPG 1015

Query: 912  RK----DLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQ 967
             K    DL L     LD+     A   +L    H    P+  L  T      S  G  + 
Sbjct: 1016 EKEPVSDLQLG----LDA-VEPTALHKTLETPAHDRAEPNSQLDSTH-----SGRGTMYS 1065

Query: 968  TLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGG---------Y 1018
            + V++ D   RT  N     +  +  P       G   + + K L  D           +
Sbjct: 1066 SWVKSPD---RTGVNFSVNSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVF 1122

Query: 1019 CSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEA 1078
            C+  +G  S +   +  +L  G+ +P             QNPPQ+KKVSLLEYRKR++EA
Sbjct: 1123 CTSEDGLVSGFGRTVNDNLIDGNCTP-------------QNPPQKKKVSLLEYRKRQREA 1169

Query: 1079 KENSAG-------GGGDSAQSKSKSAGAGQGSSNSVSDTGAH------------------ 1113
            +++ +             A     + G G  SSN   +   H                  
Sbjct: 1170 RKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSE 1229

Query: 1114 ------GVQGSSARTPSSPHKKFSPSHS-----SMSHLEAVSPSDSRGTSSS-------H 1155
                   V+ ++A   + P  +++ S S       S+  A+  SD R    S        
Sbjct: 1230 ETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVS 1289

Query: 1156 CRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADG 1215
            C P    SS       + +L+  G +P      +       P PT  +     D+     
Sbjct: 1290 CSPSHVQSSPSSHSNHIPQLQAKGPVPS-FSELMEDPDPENPEPTTTNECPSPDTSQNTC 1348

Query: 1216 EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ-SLLQQSSSPFRGHPTQSPGYSY 1274
            + P  +S   S G+ +  P++   ++     P+ +S  S  +  +        Q    S 
Sbjct: 1349 KSPPKMSKPGSPGSVI--PAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSN 1406

Query: 1275 RTTALRPGNPPS----HGSSESSLSSTSYSSPAHPVSTDSL--APFTGTP------GYFS 1322
               AL   +PP     + S + S    S  +  H   +  L   P + TP      GY S
Sbjct: 1407 NNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLS 1466

Query: 1323 SQPHSGNSTGSNLPRRSCPSSAASPTLQG-----PSDSPTSDSVSQSSTGTL-------- 1369
             +P S        P  S      +P  +      P+      +  Q+++GTL        
Sbjct: 1467 PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQ 1526

Query: 1370 SSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHY 1414
            SS ++ Q ++ SL S       P    S+ YQ  + SA  N Q+Y
Sbjct: 1527 SSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSA--NFQNY 1569


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 201/1025 (19%), Positives = 332/1025 (32%), Gaps = 177/1025 (17%)

Query: 429  PPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEE-VDNPEE 487
            PP LP             K  E+ +Q          +  + P   + + DH+   DN E 
Sbjct: 71   PPELP-------------KSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEA 117

Query: 488  KPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITT 547
             P  E     ++  N       R  R V+       + E   K+   P  +S  +   +T
Sbjct: 118  PPTSE-----ENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKST 172

Query: 548  TTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAA---EKLVP- 603
            T   T   +  KT  P  +  +++   +  S   +   +   +SQ    +    EK+   
Sbjct: 173  TGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAA 232

Query: 604  -KPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEA 662
             K        P    +    RT+ A      K     Q  +S   L +    SL  PTE 
Sbjct: 233  SKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQ----SLAEPTEH 288

Query: 663  GSLDSSG----------ENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKA 712
            G   ++           ENR  T ++ T +S      NR  +    T  +      N + 
Sbjct: 289  GGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREM 348

Query: 713  EKQECPVECPLRITTDPTVLA---TTLNMLPGLIHSPLIC---TTPKHYIRFGSPFIPER 766
               E     P   T      A   TT +      H        TTP       SP  P  
Sbjct: 349  TANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTP-------SPAEPTE 401

Query: 767  R--RRPLLPDGTFSSCKKRWIK----QALEEGMTQTSSVPQETRTQHLYQSNENSSSSSI 820
               R P   D T SS  +            E  T + + P E R +    +NEN++ S  
Sbjct: 402  HGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRER---TANENTTPS-- 456

Query: 821  CKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEE 880
                     P    ++R       T L    SPV P   N  + + +  TP  + P E  
Sbjct: 457  ---------PAGPTENRETTANEKTTL----SPVEPTE-NRETTANEKTTPSPAEPTENG 502

Query: 881  CRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSG 940
             R       +P  +  T S    P +    H +   LA     + NT      P+     
Sbjct: 503  QR-------TPFANEKTTSSSAEPTE----HGERTPLA-----NENTTPSPAEPTENRER 546

Query: 941  HSDLAPHPSLGPTSETG--FPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADG 998
             ++    PS    +E G   P  +     +L   ++   RT F      S  +A P    
Sbjct: 547  TANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSS-SAEPTEHE 605

Query: 999  LYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQ 1058
                     +R PL  +    SPAE   +R                    A E    +P 
Sbjct: 606  ---------ERTPLANENTTPSPAEPTENRER-----------------TANENTTPSPA 639

Query: 1059 NPPQRKKVSLLEY---------RKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSD 1109
             P + ++++  E            R++ A E +     +  ++  ++  A + +++S ++
Sbjct: 640  GPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAE 699

Query: 1110 TGAHGVQGSSAR-----TPSSPHKKFSPSHSSMSHLEAVSPSDSR------GTSSSHCRP 1158
               HG +   A      +P+ P +    + +  +      P+++R       T+ S  +P
Sbjct: 700  PTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQP 759

Query: 1159 QEN-----ISSRWMVPTSVERLREGGSIP----KVLRSSVRVAQKGEPSPTWESNITEKD 1209
             EN     +++    P+  E    G   P    K   SS    +  E +P    N T   
Sbjct: 760  TENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSP 819

Query: 1210 SDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQS 1269
            ++P +           +   T   P+           P    +S   + ++PF   PT++
Sbjct: 820  AEPTENR------ERTANEKTTQFPAE----------PTENRESTANEKTTPFPAEPTEN 863

Query: 1270 PGYSYR-TTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSG 1328
              ++    T L P  P  H       +  +  SPA P       PFT      SS   + 
Sbjct: 864  REWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTE 923

Query: 1329 NSTGSNLPRRSCPSSAASPTLQG---------PSDS-PTSDSVSQSSTGTLSSTSFPQNS 1378
            +   + L       S A PT  G         PS + PT    +  +  T  S++ P  +
Sbjct: 924  HGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTEN 983

Query: 1379 RSSLP 1383
                P
Sbjct: 984  GERTP 988



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 195/1004 (19%), Positives = 337/1004 (33%), Gaps = 139/1004 (13%)

Query: 488  KPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITT 547
            +P E+    +D     +H   T          H   N + ++K    P E+  +  + T 
Sbjct: 187  RPLEKSMSTLDKTSTSSHKTTTS--------FHNSGNSQTKQKSTSFP-EKITAASKTTY 237

Query: 548  TTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQA------GDIAAEKL 601
             T+ TP   E   ++  +  S+ +   T  +  +++  N    S A      G  A E  
Sbjct: 238  KTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENN 297

Query: 602  VPKPPPAKPSRPRPKSRISRYRTSSAQRLK-RQKQANAQQAELSQAALE--EGGSNSLVT 658
             P P  A+P+  R ++       S A+ ++ R++ AN   A       E  E  +N   T
Sbjct: 298  TPSP--AEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTT 355

Query: 659  -----PTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK-- 711
                 PTE G   ++ EN   + ++PT      ++ N   S    T+    T + NDK  
Sbjct: 356  LFPAEPTEHGER-TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTT 414

Query: 712  ---AEKQECPVECPL-RITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIP-ER 766
               AE  E     PL    T P+    T N       +    TTP       SP  P E 
Sbjct: 415  SSSAESTEHGERTPLANENTTPSPAEPTENRERTANEN----TTP-------SPAGPTEN 463

Query: 767  RRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNAD 826
            R        T S  +    ++      T  S        Q    +NE ++SSS       
Sbjct: 464  RETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHG 523

Query: 827  LLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPP----NSGSKSP---QLATPGSSHPGEE 879
              +PL    +     +      R  +  T P P     +G ++P   +  TP  + P E 
Sbjct: 524  ERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN 583

Query: 880  ECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNS 939
              R       +P  +  T S    P +    H +   LA      S      +R    N 
Sbjct: 584  GQR-------TPFANEKTTSSSAEPTE----HEERTPLANENTTPSPAEPTENRERTANE 632

Query: 940  GHSDLAPHPSLGPTSE---------TGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPL 990
               +  P P+ GPT           T FP+   +  +        +   E       +P 
Sbjct: 633  ---NTTPSPA-GPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPF 688

Query: 991  NAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGER-- 1048
             A  +           G+R PL  +    SPAE   +R E    +  +     P   R  
Sbjct: 689  -ANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENR-ERTANEKTTPFPAEPTENRER 746

Query: 1049 -ACEGVPSAPQNPPQRKKVSLL-------------EYRKRKQEAKENSAGGGGDSAQSKS 1094
             A E    +P  P +    + L             E  KR   A E +     +  +   
Sbjct: 747  TANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAE 806

Query: 1095 KSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSS 1154
            ++  A + +++S ++   +  + ++ +T   P +      S+ +  E  +P  +  T + 
Sbjct: 807  RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN--EKTTPFPAEPTENR 864

Query: 1155 HCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPAD 1214
                 EN +     PT  E +    +  K   S     + GE +P      T   ++P +
Sbjct: 865  EWTANENTTLSPAEPTEHEEMTPLAN-EKTTLSPAEPTENGERTPFTNEKTTPSSAEPTE 923

Query: 1215 GEGPETLSSALSKGATVYSPSRYSYQLLQCDS------PRTESQSLLQQSSSPFRGHPTQ 1268
                  L++ ++  +    P+ +  ++    +      P    ++ + + ++P    PT+
Sbjct: 924  HGERTPLANEITTPSRA-EPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTE 982

Query: 1269 ------------------SPGYSYRT----TALRPGNPPSHGSSESSLSSTSYSSPAHPV 1306
                              S  +  RT    T   P  P  HG    S +  +  SPA P 
Sbjct: 983  NGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPT 1042

Query: 1307 STDSLAPFTG---TPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQ 1363
              + + P      TP       H   +T   L       S   PT  G   +  ++ ++ 
Sbjct: 1043 EHEEMTPSANENTTPSPVKPTEHGEKTT---LANEKITLSPEGPTEHGAKTTSANEKITP 1099

Query: 1364 SSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSA 1407
            S      +       R++ P+D  T    SA +S  ++    SA
Sbjct: 1100 S-----LAKPTEHGERTTSPNDKIT---SSAAESTEHRDRATSA 1135



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 202/1100 (18%), Positives = 365/1100 (33%), Gaps = 189/1100 (17%)

Query: 412  PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQ-QNEASEENNDQQSQEVP 470
            P + R   A E   L P   +     E R R A            E  E   ++ +   P
Sbjct: 304  PTENRERTANENTTLSPAEPI-----ENRERTANENTAPFPAGPTENREMTANENTTLFP 358

Query: 471  EKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKK 530
             + T   +    +N    P E  E          H  RT  +    +     E+ E+   
Sbjct: 359  AEPTEHGERTANENTTPSPAEPTE----------HGERTANENTTPSPAEPTEHGERTPF 408

Query: 531  RRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRS 590
              D+    ++S  E T     TP+  E  T +P     N        +TP   G    R 
Sbjct: 409  ANDKT---TSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE 465

Query: 591  SQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRL---KRQKQANAQQAELSQAA 647
            + A +           P +P+  R  +   +   S A+     +R   AN +    S   
Sbjct: 466  TTANEKTTLS------PVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEP 519

Query: 648  LEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVN--RAASKYPKTKKYLV- 704
             E G    L       S     ENR  T ++ T  S      N  R      KT   L  
Sbjct: 520  TEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAE 579

Query: 705  -------TEWLNDK-----AEKQECPVECPL-RITTDPTVLATTLNMLPGLIHSPLICTT 751
                   T + N+K     AE  E     PL    T P+    T N       +    TT
Sbjct: 580  PTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN----TT 635

Query: 752  PKHYIRFGSPFIPERRRRPLLPDGT--FSSCKKRWIKQALEEGMTQTSSVPQETRTQHLY 809
            P       SP  P   R     + T  F +      ++   E  T + + P E   +  +
Sbjct: 636  P-------SPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPF 688

Query: 810  QSNENSSSSSICKDNAD---------LLSPLKKWKSRYLMEQNVTKLLRPL--------- 851
             + + +SSS+   ++ +          LSP +  ++R   E+   +   P          
Sbjct: 689  ANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENR---ERTANEKTTPFPAEPTENRE 745

Query: 852  -------SPVTPPPPNSGSKSP---QLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRC 901
                   +P    P  +G ++P   +  TP  + P E   R       +P  +  T S  
Sbjct: 746  RTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR-------TPFANEKTTSSS 798

Query: 902  NTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHP-----SLGPTSET 956
              P +    H +   LA      S      +R    N   +     P     S      T
Sbjct: 799  AEPTE----HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTT 854

Query: 957  GFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLV-GDRKPLHLD 1015
             FP+   +  +     +      E       +PL        L    P   G+R P   +
Sbjct: 855  PFPAEPTENREWTANENTTLSPAEPTEHEEMTPL--ANEKTTLSPAEPTENGERTPFTNE 912

Query: 1016 GGYCSPAEGFSSRYEHGLMKDL-------SRGSLSPGGER-ACEGVPSAPQNPPQRKKVS 1067
                S AE      EHG    L       SR   +  GER A E    +P  P +  + +
Sbjct: 913  KTTPSSAE----PTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETT 968

Query: 1068 LLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSP- 1126
            +           E++     +  ++  ++  A + ++ S +++  HG + ++ +T  SP 
Sbjct: 969  V----------NEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPA 1018

Query: 1127 ------------HKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVER 1174
                        ++K  PS +  +  E ++PS +  T+ S  +P E+     +    +  
Sbjct: 1019 EPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITL 1078

Query: 1175 LREG---------GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSAL 1225
              EG          +  K+  S  +  + GE + +    IT   ++  +     T ++ +
Sbjct: 1079 SPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVI 1138

Query: 1226 SKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPP 1285
            +       P +++ +        T +   + Q +     HP ++   + +TT   P  P 
Sbjct: 1139 TPAPA--EPIKHAKR-------TTLAHEKMTQVTEKSTEHPEKTTSTTEKTTR-TPEKPT 1188

Query: 1286 SHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAA 1345
             +  SE ++ +   ++P     T++L                GN+T +    ++   S  
Sbjct: 1189 LY--SEKTICTKGKNTPVPEKPTENL----------------GNTTLTTETIKAPVKSTE 1230

Query: 1346 SPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRV 1405
            +P            SV  +   +L++TS      S L     T  +P+   + +   +++
Sbjct: 1231 NPEKTAAVTKTIKPSVKVTGDKSLTTTS------SHLNKTEVTHQVPTGSFTLITSRTKL 1284

Query: 1406 SAVSN----SQHYPHRGSGG 1421
            S++++    ++ +P+    G
Sbjct: 1285 SSITSEATGNESHPYLNKDG 1304


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 44/183 (24%), Positives = 86/183 (46%), Gaps = 14/183 (7%)

Query: 286  LRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGN 345
            LRAA+DL  +T ++EY G+V+  ++F+     + +      ++      E+ +DA   GN
Sbjct: 1564 LRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEI-IDATQKGN 1622

Query: 346  DARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACH 405
             +RF+  SC PN E +    +G + +  +    +   +E+T  FDY++     +    C 
Sbjct: 1623 CSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELT--FDYQFQRYGKEAQ-KCF 1679

Query: 406  KGNRNCPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQ 465
             G+ NC       N           S+   G + ++ ++R+K+  ++ + EA  EN +  
Sbjct: 1680 CGSANCRGYLGGENRV---------SIRAAGGKMKKERSRKKD-SVDGELEALMENGEGL 1729

Query: 466  SQE 468
            S +
Sbjct: 1730 SDK 1732



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 53/256 (20%), Positives = 91/256 (35%), Gaps = 32/256 (12%)

Query: 417  NPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVS 476
            N +    PL  P PS       T       K+L   +    SE + D    +   ++   
Sbjct: 1847 NTSRAHTPLNTPDPSTKL---STEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGK 1903

Query: 477  SDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPL 536
               E++D  E  P EE+EE+         S++    +  E  + +  N+E  K    +P 
Sbjct: 1904 DGKEDLDQLENVPVEEEEEL--------QSQQLLPQQLPECKVDSETNIEASKLPTSEPE 1955

Query: 537  EQSNSD-VEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVN---TRRSSQ 592
              +  +  E   T  E P+ EET ++  E  VS+  S  +     ++V ++   T+    
Sbjct: 1956 ADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDS 2015

Query: 593  AGDIAAEKLVPKPPPA----------------KPSRPRPKS-RISRYRTSSAQRLKRQKQ 635
              D+     +PK                    +   P PK+   SR R    Q   ++K+
Sbjct: 2016 WKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKR 2075

Query: 636  ANAQQAELSQAALEEG 651
                      +A E G
Sbjct: 2076 KRRSSLSPPSSAYERG 2091


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 98/347 (28%), Positives = 138/347 (39%), Gaps = 27/347 (7%)

Query: 1082 SAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPS-SPHKKFSPSHSSMSHL 1140
            S+   G S  S S  A      ++  SD+G      S A TPS S    FS S +S+   
Sbjct: 22   SSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASI--- 78

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLR-SSVRVAQKGEPSP 1199
                PSDS   S S         S W  P++      G SIP     +S  V+    PS 
Sbjct: 79   ----PSDSGWASPSASWASTPSDSGWASPSA-----SGASIPSDSGWASPSVSGASIPSA 129

Query: 1200 TWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSS 1259
             W S      S P+D       +S  +  A+  S S ++       SP     S     +
Sbjct: 130  FWASPSASGASTPSD----SGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGA 185

Query: 1260 SPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSY-SSPAHPVSTDSLAPFTGTP 1318
            S        SP   + + +    + PS     S+ S + + SS A  +S  +    T + 
Sbjct: 186  STPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSD 245

Query: 1319 GYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDS--VSQSSTGTLSSTSF-- 1374
              ++S   S  ST ++    S  S  AS +     DS TSDS  V  S++   SS S+  
Sbjct: 246  SGWASPSASWVSTSTSRASTSSDSGWASSSASW--DSITSDSGWVCPSASWASSSASWAS 303

Query: 1375 -PQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSG 1420
             P +S SS PS  R  +L  +G  A + AS  SA S+S    H  SG
Sbjct: 304  APSDSGSSSPSVSRASTLSVSGW-ASFSASGASAPSDSGWTSHSASG 349



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 83/324 (25%), Positives = 121/324 (37%), Gaps = 35/324 (10%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDS 1148
            S  S S  A      ++  SD+G      S A  PS+     SPS S  S     +PSDS
Sbjct: 93   STPSDSGWASPSASGASIPSDSGWASPSVSGASIPSAFWA--SPSASGAS-----TPSDS 145

Query: 1149 RGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT--WESNIT 1206
               S S      +  S W  P++                +   +  G  SP+  W S  T
Sbjct: 146  GWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPST 205

Query: 1207 EKDSDPADGEGPETLSSA--LSKGATVYSPSRY---------------SYQLLQCDSPRT 1249
               S P+D     T S +   S  A+  SPS                 S+         T
Sbjct: 206  SWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRAST 265

Query: 1250 ESQSLLQQSSSPFRGHPTQS----PGYSYRTTALRPGNPPSH-GSSESSLSSTSYSSPAH 1304
             S S    SS+ +    + S    P  S+ +++    + PS  GSS  S+S  S  S + 
Sbjct: 266  SSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSG 325

Query: 1305 PVSTDSLAPFTGTPGYFSSQPHSGNSTGSNL----PRRSCPSSAASPTLQGPSDSPTSDS 1360
              S  +      +   ++S   SG ST S+     P  S  S+++      PS S  S S
Sbjct: 326  WASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPS 385

Query: 1361 VSQSSTGTLSSTSFPQNSRSSLPS 1384
             S +ST + S  + P  S +S+PS
Sbjct: 386  ASGASTPSDSGWASPSASGASMPS 409


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 226/1162 (19%), Positives = 392/1162 (33%), Gaps = 209/1162 (17%)

Query: 417  NPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVS 476
            +P++TE   LP  P+ P++  ++       +        +A+       S  V E+ + S
Sbjct: 2975 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS------PDATLSPATTTSSGVSEESSTS 3028

Query: 477  SDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPL 536
                   +    P+      +  +   +HS +       EA +           ++    
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG----STEATLSPGSTTASSLGQQSTTF 3084

Query: 537  EQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDI 596
              S  D E T    +T      +   P    + S+     P++  S G+    ++     
Sbjct: 3085 HSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP 3144

Query: 597  AAEKLVPKPP-----PAKPS---RPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAAL 648
            ++    P PP     P + S     RP S  + + ++S+  L R +++    +       
Sbjct: 3145 SSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS------ 3198

Query: 649  EEGGSNSLVTPTEAGSLDSSGE--NRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTE 706
              G + + + PT + +    GE    P++       ++ GS      S+   T       
Sbjct: 3199 -PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT------- 3250

Query: 707  WLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPER 766
                     +  +      ++  +  +TT +  PG  H+             GS  +P  
Sbjct: 3251 -FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---------GSTTMPG- 3299

Query: 767  RRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNAD 826
                +  + T S          L  G T  SS+  E+ T H   S   S+ +++  DN  
Sbjct: 3300 ----VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH---SGPGSTETTLLPDNTT 3352

Query: 827  LLSPLKKWKSRYLMEQNVTKLLRPLSPVT------------------PPPPNSGSKSPQL 868
                L+     +    +    L P    T                  P PP + S   +L
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412

Query: 869  ATPGSSHPGEE-------------ECRNGYSLMFSPVTSLTTASRC-------------- 901
            +T     P                      ++  SPV + TT S                
Sbjct: 3413 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTY 3472

Query: 902  -NTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAP--------HPSLGP 952
             ++P   +  H  + D    G  + +T S +     ++S  S  +         H S G 
Sbjct: 3473 HSSPGSTQTMHFPESDTTS-GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 3531

Query: 953  TSETGFP---SRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAM-------PRADGLYRG 1002
            T+ T FP   + SG   ++   +S Q   T   ++ A S  + +       P + G    
Sbjct: 3532 TATTHFPDSSTTSGRSEESTASHSSQD-ATGTIVLPARSTTSVLLGESTTSPISSGSMET 3590

Query: 1003 SPLVGD-------RKPLHLDGGYCSPAEGFS--SRYEHGLMKDLSRGSLSPGGERACEGV 1053
            + L G         K         SPA   S  S    G+ ++ +     PG        
Sbjct: 3591 TALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTT-AF 3649

Query: 1054 PSAPQNP------------PQRKKVSLLEYR-----KRKQEAKENSAGGGGDSAQSKSKS 1096
            P +   P            P     +LL          ++    +S+ G  D+A S   +
Sbjct: 3650 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGST 3709

Query: 1097 AGAGQGSSNSV--------------SDTGAHGVQGSSARTPSS---PHKKFSPSHSSMSH 1139
                 G  ++                 T + G+  +S R  SS   P    SP+ S+   
Sbjct: 3710 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 3769

Query: 1140 LEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKV-LRSSVRVAQKGEPS 1198
            L+  S +     +S+H  P    ++   V  S    R  GS P     +S   +   E S
Sbjct: 3770 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 3829

Query: 1199 PTWESNITEKDSDPA------DGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ 1252
              + S+     + P+       G G E+ +S +S G+T  +             P + + 
Sbjct: 3830 TIFHSSPDASGTTPSSAHSTTSGRG-ESTTSRISPGSTEIT-----------TLPGSTTT 3877

Query: 1253 SLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLA 1312
              L ++S+ F   P +SP     TT L P +  S G  E   S+TS S P    ST S A
Sbjct: 3878 PGLSEASTTFYSSP-RSP-----TTTLSPASMTSLGVGEE--STTSRSQPGSTHSTVSPA 3929

Query: 1313 PFTGTPG-------YFSSQPHSGNSTGSNLPRRSCPS-SAASPTL--QGPSDSPTSDSVS 1362
              T TPG        +SS P  G++  +  PR +  S     PT     P+ + T+    
Sbjct: 3930 S-TTTPGLSEESTTVYSSSP--GSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTE 3986

Query: 1363 QSSTGTLS--STSF---PQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHR 1417
             S+T  L+  ST+F   P ++++ LP+ L T  L    +S  + +S  S  +        
Sbjct: 3987 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADL--GEESTTFPSSSGSTGTKLSPARST 4044

Query: 1418 GSGGVHQYRLQPLQGSGVKTQT 1439
             SG V +     L  S  +T T
Sbjct: 4045 TSGLVGESTPSRLSPSSTETTT 4066



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 227/991 (22%), Positives = 348/991 (35%), Gaps = 158/991 (15%)

Query: 535  PLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAG 594
            P   ++S V   +TTS +  G    T  P+S            +TP     +T   S  G
Sbjct: 2065 PASTTSSGVSEESTTSHSRPGSTHTTAFPDST-----------TTPGLSRHSTTSHSSPG 2113

Query: 595  DIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSN 654
                  L      + PS+    S  S   T +A         +  Q E +      G ++
Sbjct: 2114 STDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ-ESTTFHSSPGSTH 2172

Query: 655  SLVTP---TEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK 711
            + + P   T +G +++S      TGS  T +S         AS      +   T +    
Sbjct: 2173 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS--------PASSTSPGLQGESTAFQTHP 2224

Query: 712  AEKQECPVECPLRITTDPTVLATTLNMLPG---LIHSPLICTTPKHYIRFGSPFIPERRR 768
            A     P   P    T P   +TT +  PG     H P   TT  H  +  + F      
Sbjct: 2225 ASTHTTP--SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSPDA 2281

Query: 769  RPLLPDGTFSSCKKRW--IKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNAD 826
                P    S+   R       +  G T+ +++P  T T  L +++    SS   +    
Sbjct: 2282 SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP--RSPTT 2339

Query: 827  LLSPLKKWKSRYLMEQNVTKLLRP---LSPVTPPPPNSGSKSPQLATPGSSHPGEEECRN 883
             LSP     S  + E++ T   +P    S V+P    +   S +  T  SS PG  E   
Sbjct: 2340 TLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE--- 2395

Query: 884  GYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADR--------PS 935
              + +F P T  TT+ R   P  F   H +        + + +T S            P+
Sbjct: 2396 --TTVF-PRTP-TTSVRGEEPTTF---HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 2448

Query: 936  LLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPR 995
               +G         LG  S T FPS SG    TL      A  T   L+   +P    P 
Sbjct: 2449 STQTGLPATLTTADLGEESTT-FPSSSGSTGTTL----SPARSTTSGLVGESTPSRLSPS 2503

Query: 996  ADGLYR--GSPLVGD---------RKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSP 1044
            +       GSP               P   D    SPA   SS    G+ ++ S     P
Sbjct: 2504 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL-SPATTTSS----GVSEESSTSHSQP 2558

Query: 1045 GGERACEGVPSAPQNP------------PQRKKVSLLEYRKR-----KQEAKENSAGGGG 1087
            G        P +   P            P     +LL          ++    +S+ G  
Sbjct: 2559 GSTHTT-AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2617

Query: 1088 DSAQSKSKSAGAGQGSSNSV--------------SDTGAHGVQGSSARTPSS---PHKKF 1130
            D+A S   +     G  ++                 T + G+  +S R  SS   P    
Sbjct: 2618 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2677

Query: 1131 SPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKV-LRSSV 1189
            SP+ S+   L+  S +     +S+H  P    ++   V  S    R  GS P     +S 
Sbjct: 2678 SPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2737

Query: 1190 RVAQKGEPSPTWESNITEKDSDPA------DGEGPETLSSALSKGATVYSPSRYSYQLLQ 1243
              +   E S  + S+     + P+       G G E+ +S +S G+T  +          
Sbjct: 2738 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG-ESTTSRISPGSTEIT---------- 2786

Query: 1244 CDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPA 1303
               P + +   L ++S+ F   P +SP     TT L P +  S G  E   S+TS S P 
Sbjct: 2787 -TLPGSTTTPGLSEASTTFYSSP-RSP-----TTTLSPASMTSLGVGEE--STTSRSQPG 2837

Query: 1304 HPVSTDSLAPFTGTPG-------YFSSQPHSGNSTGSNLPRRSCPS-SAASPTL--QGPS 1353
               ST S A  T TPG        +SS P  G++  +  PR +  S     PT     P+
Sbjct: 2838 STHSTVSPAS-TTTPGLSEESTTVYSSSP--GSTETTVFPRSTTTSVRGEEPTTFHSRPA 2894

Query: 1354 DSPTSDSVSQSSTGTLS--STSF---PQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAV 1408
             + T+     S+T  L+  ST+F   P ++++ LP+ L T  L    +S  + +S  S  
Sbjct: 2895 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL--GEESTTFPSSSGSTG 2952

Query: 1409 SNSQHYPHRGSGGVHQYRLQPLQGSGVKTQT 1439
            +         SG V +     L  S  +T T
Sbjct: 2953 TTLSPARSTTSGLVGESTPSRLSPSSTETTT 2983



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 228/1165 (19%), Positives = 391/1165 (33%), Gaps = 215/1165 (18%)

Query: 417  NPNATELPLLPPPPSLPTIGAE--TRRRKARRKELEMEQ----QNEASEENNDQQSQEVP 470
            +P++TE   LP  P+ P++  +  T     R  +  +       +  SEE++   SQ   
Sbjct: 1418 SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 1477

Query: 471  EKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKK 530
               T   D     +  ++P              +HS +       EA +           
Sbjct: 1478 THTTAFPDSTTTSDLSQEP------------TTSHSSQG----STEATLSPGSTTASSLG 1521

Query: 531  RRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRS 590
            ++      S  D E T    +T      +   P    + S+     P++  S G+    +
Sbjct: 1522 QQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 1581

Query: 591  SQAGDIAAEKLVPKPP-----PAKPS---RPRPKSRISRYRTSSAQRLKRQKQANAQQAE 642
            +     ++    P PP     P + S     RP S  + + ++S+  L R +++    + 
Sbjct: 1582 TFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 1641

Query: 643  LSQAALEEGGSNSLVTPTEAGSLDSSGE--NRPLTGSDPTVVSITGSHVNRAASKYPKTK 700
                    G + + + PT + +    GE    P++       ++ GS      S+   T 
Sbjct: 1642 -------PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT- 1693

Query: 701  KYLVTEWLNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGS 760
                           +  +      ++  +  +TT +  PG  H+             GS
Sbjct: 1694 -------FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---------GS 1737

Query: 761  PFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSI 820
              +P      +  + T S          L  G T  SS+  E+ T H   S+  S+ +++
Sbjct: 1738 TTMPG-----VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH---SSPGSTETTL 1789

Query: 821  CKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVT------------------PPPPNSG 862
              DN      L+     +    +    L P    T                  P PP + 
Sbjct: 1790 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1849

Query: 863  SKSPQLATPGSSHPGEE-------------ECRNGYSLMFSPVTSLTTASRCNTPL---- 905
            S   +L+T     P                      ++  SPV + TT S   +      
Sbjct: 1850 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 1909

Query: 906  -QFELCHRKDLDLAKVGYLDSNT---NSCADRPSLLNSGHSDLAP--------------H 947
             +    H        + + +S+T    S   R S  ++ H+  +P              H
Sbjct: 1910 EESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 1969

Query: 948  PSLGPTSETGFP---SRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAM-------PRAD 997
             S G T+ T FP   + SG   ++   +S Q   T   ++ A S  + +       P + 
Sbjct: 1970 SSPGSTATTHFPDSSTTSGRSEESTASHSSQD-ATGTIVLPARSTTSVLLGESTTSPISS 2028

Query: 998  GLYRGSPLVGD-------RKPLHLDGGYCSPAEGFS--SRYEHGLMKDLSRGSLSPGGER 1048
            G    + L G         K         SPA   S  S    G+ ++ +     PG   
Sbjct: 2029 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH 2088

Query: 1049 ACEGVPSAPQNP------------PQRKKVSLLEYRKR-----KQEAKENSAGGGGDSAQ 1091
                 P +   P            P     +LL          ++    +S+ G  D+A 
Sbjct: 2089 TT-AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2147

Query: 1092 SKSKSAGAGQGSSNSV--------------SDTGAHGVQGSSARTPSS---PHKKFSPSH 1134
            S   +     G  ++                 T + G+  +S R  SS   P    SP+ 
Sbjct: 2148 SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 2207

Query: 1135 SSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKV-LRSSVRVAQ 1193
            S+   L+  S +     +S+H  P    ++   V  S    R  GS P     +S   + 
Sbjct: 2208 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG 2267

Query: 1194 KGEPSPTWESNITEKDSDPA------DGEGPETLSSALSKGATVYSPSRYSYQLLQCDSP 1247
              E S  + S+     + P+       G G E+ +S +S G+T  +             P
Sbjct: 2268 HSEKSTIFHSSPDASGTTPSSAHSTTSGRG-ESTTSRISPGSTEIT-----------TLP 2315

Query: 1248 RTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVS 1307
             + +   L ++S+ F   P +SP     TT L P +  S G  E   S+TS S P    S
Sbjct: 2316 GSTTTPGLSEASTTFYSSP-RSP-----TTTLSPASMTSLGVGEE--STTSRSQPGSTHS 2367

Query: 1308 TDSLAPFTGTPG-------YFSSQPHSGNST-GSNLPRRSCPSSAASPTLQGPSDSPTSD 1359
            T S A  T TPG        +SS P S  +T     P  S      +     P+ + T+ 
Sbjct: 2368 TVSPAS-TTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTL 2426

Query: 1360 SVSQSSTGTLS--STSF---PQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHY 1414
                S+T  L+  ST+F   P ++++ LP+ L T  L    +S  + +S  S  +     
Sbjct: 2427 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL--GEESTTFPSSSGSTGTTLSPA 2484

Query: 1415 PHRGSGGVHQYRLQPLQGSGVKTQT 1439
                SG V +     L  S  +T T
Sbjct: 2485 RSTTSGLVGESTPSRLSPSSTETTT 2509



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 137/581 (23%), Positives = 215/581 (37%), Gaps = 122/581 (20%)

Query: 855  TPPPPNSGSKSPQLATPGSSHPG--EEECRNGYSLMFSPVTSLTTASRCNTPLQFE--LC 910
            T  P +SGS +   A PGS+      E+    YS   SP T+L+ AS  ++ +  E    
Sbjct: 4304 TTSPISSGS-TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362

Query: 911  HRKDLDLAKVGYLDSNTNSCADRPSLLNS---GHSDLAPHP------SLGPTSETGFPSR 961
            H +   +    +  S T     + S  +    G +D    P      SLGP S T F S 
Sbjct: 4363 HSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTT-FHSS 4421

Query: 962  SGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSP 1021
             G    TL+ ++     T   L+ A +P+++         GSP                 
Sbjct: 4422 PGSTETTLLPDNT----TASGLLEASTPVHSST-------GSP----------------- 4453

Query: 1022 AEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKEN 1081
                               +LSP G    +G  +  Q+ P  K  +           + +
Sbjct: 4454 -----------------HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELS 4496

Query: 1082 SAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL- 1140
            +   G  S+   +  + +      S   T  H    ++A TPS       P+ S+ S L 
Sbjct: 4497 TTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS-------PARSTTSGLV 4549

Query: 1141 -EAVSPSDSRGTSSSHCRPQENISS---RWMVPTSVERLREGGSIPKVLRSSVRVAQKGE 1196
             E+ +   S G++ +   P+ N +S        +         S P    + V       
Sbjct: 4550 EESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 4609

Query: 1197 PSPTWESNITEKDSDPADGEGPETLSSALSKGAT--VYSPSRYSYQLLQCDSPRTESQSL 1254
             SP   +     DS    G   E+ +S  S+ AT  +  P+R            T S  L
Sbjct: 4610 SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR-----------STTSVLL 4658

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPF 1314
             + ++SP       S G S  TTAL PG+  + G SE S  +T +SSP+           
Sbjct: 4659 GESTTSPI------SSG-SMETTAL-PGSTTTPGLSEKS--TTFHSSPSS---------- 4698

Query: 1315 TGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQS-----STGTL 1369
            T T  + +S    G S  S     S  ++A +P+   P+ S TS  V +S     S G+ 
Sbjct: 4699 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPS---PARSTTSGLVEESTAYHSSPGST 4755

Query: 1370 SSTSFPQN---------SRSSLPSDLRTISLPSAGQSAVYQ 1401
             +  FP++         SR+S  S   TIS P +  SA+ +
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 4796



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 91/342 (26%), Positives = 138/342 (40%), Gaps = 37/342 (10%)

Query: 1106 SVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSD-SRGTSSSHCRPQENISS 1164
            ++S  G+   QG S    S P  K +      +    V PS  S G+ SS   P  +IS+
Sbjct: 761  TLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI--PTTHISA 818

Query: 1165 RWMVPTSVERLREGGSIPKVLRS-----SVRVAQKGEPSPTWESNITEKDSDPADG---- 1215
            R      VE      S P   ++     S   + +GE S T  S+ T   S         
Sbjct: 819  RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 878

Query: 1216 -EGPETLSSALSKGATVYSP-----SRYSYQLLQCDSPRTESQSLL---QQSSSPFRGHP 1266
             E P +  S+    AT + P     S  S +     S +  + +++   + ++S   G  
Sbjct: 879  VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 938

Query: 1267 TQSP--GYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQ 1324
            T SP    S  TTAL PG+  + G SE S  +T +SSP  P +T  L+P + T    S +
Sbjct: 939  TTSPISSGSMETTAL-PGSTTTPGLSERS--TTFHSSPRSPATT--LSPASTTSSGVSEE 993

Query: 1325 PHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPS 1384
              +  S   +    + P S  +P L   S      + S SS G+  +T  P ++ +S PS
Sbjct: 994  STTSRSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTTSGPS 1047

Query: 1385 DLRTISLPSAGQS-AVYQASRVSAVSNSQHYP--HRGSGGVH 1423
               T S  S+G +         +A+S  Q     H   G  H
Sbjct: 1048 QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 194/903 (21%), Positives = 311/903 (34%), Gaps = 167/903 (18%)

Query: 535  PLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVS--NVTIPSTPQSVGVNTRRSSQ 592
            P   ++S V   +TTS +  G    T  P+S  +  +S  + T  S+P S          
Sbjct: 3622 PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT------ 3675

Query: 593  AGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGG 652
                    L+P       S     +  S   ++          A +   E +      G 
Sbjct: 3676 --------LLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGS 3727

Query: 653  SNSLVTP---TEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLN 709
            +++ + P   T +G +++S      TGS  T +S         AS      +   T +  
Sbjct: 3728 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS--------PASSTSPGLQGESTAFQT 3779

Query: 710  DKAEKQECPVECPLRITTDPTVLATTLNMLPG---LIHSPLICTTPKHYIRFGSPFIPER 766
              A     P   P    T P   +TT +  PG     H P   TT  H  +  + F    
Sbjct: 3780 HPASTHTTP--SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSP 3836

Query: 767  RRRPLLPDGTFSSCKKRW--IKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDN 824
                  P    S+   R       +  G T+ +++P  T T  L +++    SS   +  
Sbjct: 3837 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP--RSP 3894

Query: 825  ADLLSPLKKWKSRYLMEQNVTKLLRP---LSPVTPPPPNSGSKSPQLATPGSSHPGEEEC 881
               LSP     S  + E++ T   +P    S V+P    +   S +  T  SS PG  E 
Sbjct: 3895 TTTLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE- 3952

Query: 882  RNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGH 941
                + +F    S TT+ R   P  F   H +        + + +T S     S      
Sbjct: 3953 ----TTVFP--RSTTTSVRREEPTTF---HSRPASTHTTLFTEDSTTSGLTEES------ 3997

Query: 942  SDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYR 1001
                  P    +++TG P+       TL         T F            P + G   
Sbjct: 3998 ---TAFPGSPASTQTGLPA-------TLTTADLGEESTTF------------PSSSGS-- 4033

Query: 1002 GSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPP 1061
                          G   SPA   +S    GL+ + +   LSP        +P +P  P 
Sbjct: 4034 -------------TGTKLSPARSTTS----GLVGESTPSRLSPSSTETTT-LPGSPTTPS 4075

Query: 1062 QRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSAR 1121
              +K +      R  +A  + A         +S ++ +  GS+++ +   +    G S +
Sbjct: 4076 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS-Q 4134

Query: 1122 TPSSPHKK-------FSPSHSSMSHLEAVSPS--DSRGTSSSHCRPQENISSRWMVPTSV 1172
             P++ H          SP  ++ S L   S +   S G + +   P + I+S  +V  S 
Sbjct: 4135 EPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEAST 4193

Query: 1173 ERLREGGSIPKVLR----SSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSAL--- 1225
                  GS+   L     +S  + ++     +W S+     S P+    P  +S+     
Sbjct: 4194 PTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSR 4253

Query: 1226 --SKGATVYSPS-----RYSYQLLQCDSPRTESQSLL--QQSSSPFRGHPTQSP--GYSY 1274
              S   T +S S     R         SP     +L   + ++S   G PT SP    S 
Sbjct: 4254 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 4313

Query: 1275 RTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSN 1334
             TTAL PG+  + G SE S  +T YSSP  P +T                          
Sbjct: 4314 ETTAL-PGSTTTAGLSEKS--TTFYSSPRSPDTT-------------------------- 4344

Query: 1335 LPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA 1394
                    S AS T  G S+  T+   S S  G++ +T+FP ++     S   T S  S 
Sbjct: 4345 -------LSPASTTSSGVSEESTT---SHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394

Query: 1395 GQS 1397
            G +
Sbjct: 4395 GST 4397



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 85/314 (27%), Positives = 123/314 (39%), Gaps = 29/314 (9%)

Query: 1124 SSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPK 1183
            S+P   FS S +++ H E  +P  S   +++   P    ++   V  S    R  GS   
Sbjct: 454  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQT 513

Query: 1184 V-LRSSVRVAQKGEPSPTWESNITE-KDSDPADGEGPETLSSALSKGATVYSPSRYSYQL 1241
            +    S   +   E S T+  + T  K S P+        S   S G+T  +  R S  +
Sbjct: 514  MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 573

Query: 1242 --------LQCDSPRTESQSLLQQSSSP--FRGHPTQSP--GYSYRTTALRPGNPPSHGS 1289
                        SP   + ++L   S+P    G  T SP    S  TTAL PG+    G 
Sbjct: 574  SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGL 632

Query: 1290 SESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASP-- 1347
            SE   S+T YSSP  P +T    P + T    S +  + +S   +    + P S   P  
Sbjct: 633  SEK--STTFYSSPRSPDTTH--LPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL 688

Query: 1348 ----TLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLP-SAGQSAVYQA 1402
                T    S  PT  ++S  ST T SS      +  S P    T  LP +   S + +A
Sbjct: 689  SQESTASHSSPGPTDTTLSPGST-TASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 747

Query: 1403 SRVSAVSNSQHYPH 1416
            S    V +S   PH
Sbjct: 748  S--MPVHSSTRSPH 759



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 154/663 (23%), Positives = 236/663 (35%), Gaps = 117/663 (17%)

Query: 789  LEEGMTQTSSVPQETRTQHLYQSNE---NSSSSSICKDNADL--LSPLKKWKSRYLMEQN 843
            +EE  T   S P  T T H   S+    +S  S+I   + D    +P     +     ++
Sbjct: 1158 VEESTTYHRS-PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 1216

Query: 844  VTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNT 903
             T  + P S      P S +      TPG S    E     YS   SP T+L+ AS  + 
Sbjct: 1217 TTSRISPGSTEITTLPGSTT------TPGLS----EASTTFYSSPRSPTTTLSPASMTSL 1266

Query: 904  PLQFELCHRKDLD---LAKVGYLDSNTNSCADRPSLLNS---GHSDLAPHPSLGPTSETG 957
             +  E    +       + V    + T   ++  + + S   G ++    P    TS  G
Sbjct: 1267 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHG 1326

Query: 958  -----FPSRSGDGHQTL-VRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKP 1011
                 F SR    H TL   +S  +  TE +  +  SP +           + L  +   
Sbjct: 1327 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 1386

Query: 1012 LHLDGGYC----SPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVS 1067
                 G      SPA   +S    GL+ + +   LSP        +P +P  P   +K +
Sbjct: 1387 FPSSSGSTGTKLSPARSTTS----GLVGESTPSRLSPSSTETTT-LPGSPTTPSLSEKST 1441

Query: 1068 LLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGS--------SNSVSD-----TGAHG 1114
                  R  +A  + A         +S ++ +  GS        S + SD     T +H 
Sbjct: 1442 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 1501

Query: 1115 VQGSSARTPSSPHKKFSPSHSSMSHLEAVSPS--DSRGTSSSHCRPQENISSRWMVPTSV 1172
             QGS+  T        SP  ++ S L   S +   S G + +   P + I+S  +V  S 
Sbjct: 1502 SQGSTEAT-------LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEAST 1553

Query: 1173 ERLREGGSIPKVLR----SSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSAL--- 1225
                  GS+   L     +S  + ++     +W S+     S P     P  +S+     
Sbjct: 1554 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR 1613

Query: 1226 --SKGATVYSPS-----RYSYQLLQCDSPRTESQSLL--QQSSSPFRGHPTQSP--GYSY 1274
              S   T +S S     R         SP     +L   + ++S   G PT SP    S 
Sbjct: 1614 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1673

Query: 1275 RTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSN 1334
             TTAL PG+  + G SE S  +T YSSP  P +T                          
Sbjct: 1674 ETTAL-PGSTTTAGLSEKS--TTFYSSPRSPDTT-------------------------- 1704

Query: 1335 LPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA 1394
                    S AS T  G S+  T+   S S  G+  +T+FP ++     S   T S  S 
Sbjct: 1705 -------LSPASTTSSGVSEESTT---SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1754

Query: 1395 GQS 1397
            G +
Sbjct: 1755 GST 1757



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 86/354 (24%), Positives = 132/354 (37%), Gaps = 35/354 (9%)

Query: 1094 SKSAGAGQGSSNSVSDTGAHGVQ---GSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRG 1150
            S ++G  + S+ S S  GA G       SA +      K SP  S+     A+  S +  
Sbjct: 215  STNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTA 274

Query: 1151 TSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDS 1210
              S      E  ++ +  P S +R            S         P PT    I   DS
Sbjct: 275  GLS------EKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPT--HTIAFPDS 326

Query: 1211 DPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSP 1270
                G   E+ +S    G+T  + S           P T + S L   S+ F      SP
Sbjct: 327  TTMPGVSQESTASHSIPGSTDTTLS-----------PGTTTPSSLGPESTTFHS----SP 371

Query: 1271 GYSYRTTALRPGNPPSHGSSESSLS-STSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGN 1329
            GY+ +TT L P N  + G  E+S    +S  SP   +S  S     G P  F S P S +
Sbjct: 372  GYT-KTTRL-PDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKD 429

Query: 1330 STGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNS----RSSLPSD 1385
            ++ +     S     ++     PS +PT+   + S+T   S  S P +S     ++ P  
Sbjct: 430  TSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP 489

Query: 1386 LRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQT 1439
             R+ +     +S  Y  S  S  + + H+P   +   H        GS   T++
Sbjct: 490  ARSATSGHVEESTAYHRSPGS--TQTMHFPESSTTSGHSEESATFHGSTTHTKS 541



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 96/394 (24%), Positives = 145/394 (36%), Gaps = 97/394 (24%)

Query: 1075 KQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSV--------------SDTGAHGVQGSSA 1120
            ++    +S+ G  D+A S   +     G  ++                 T + G+  +S 
Sbjct: 1048 QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST 1107

Query: 1121 RTPSS---PHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLRE 1177
            R  SS   P    SP+ S+   L+  S +     +S+H  P    ++   V  S    R 
Sbjct: 1108 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 1167

Query: 1178 GGSIPKV-LRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSR 1236
             GS P     +S   +   E S  + S      S  A G  P +  S  S G    + SR
Sbjct: 1168 PGSTPTTHFPASSTTSGHSEKSTIFHS------SPDASGTTPSSAHSTTS-GRGESTTSR 1220

Query: 1237 YSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSS 1296
                                            SPG +  TT   PG+  + G SE+  S+
Sbjct: 1221 I-------------------------------SPGSTEITTL--PGSTTTPGLSEA--ST 1245

Query: 1297 TSYSSPAHPVSTDSLAPFT----GTPGYFS-SQPHSGNSTGSNLPRRSCPSSAASPTLQG 1351
            T YSSP  P +T S A  T    G     S SQP S +ST S       P+S  +P L  
Sbjct: 1246 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-------PASTTTPGL-- 1296

Query: 1352 PSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTI--SLPSAGQSAVYQASRVSA-- 1407
               S  S +V  SS G+  +T FP ++ +S+  +  T   S P++  + ++     ++  
Sbjct: 1297 ---SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGL 1353

Query: 1408 VSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGL 1441
               S  +P                GS   TQTGL
Sbjct: 1354 TEESTAFP----------------GSPASTQTGL 1371



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 78/323 (24%), Positives = 130/323 (40%), Gaps = 33/323 (10%)

Query: 1120 ARTPSSPHKKFSPSHSSMSHLE-AVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG 1178
            +R  S+P   FS S +++   E + +   S G + +   P  + +S  +   +   +  G
Sbjct: 4252 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 4311

Query: 1179 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS 1238
             +    L  S   A   E S T+ S+    D+  +      T SS +S+ +T       S
Sbjct: 4312 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS---TTSSGVSEESTTSHSRPGS 4368

Query: 1239 YQLLQCDSPRTE---SQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSH---GSSES 1292
                   S  T    SQ      SSP     T SPG S   ++L P +   H   GS+E+
Sbjct: 4369 MHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPG-STTASSLGPESTTFHSSPGSTET 4427

Query: 1293 SL-------------SSTSYSSPAHPVSTDSLAPFTGTPGY---FSSQPHSGNSTGSNLP 1336
            +L             S+  +SS   P +T S A  T   G    F S P+S ++T +   
Sbjct: 4428 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPT 4487

Query: 1337 RRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNS----RSSLPSDLRTISLP 1392
              S     ++ +   PS +PT+   + S+T   S  S   +S     ++ PS  R+ +  
Sbjct: 4488 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 4547

Query: 1393 SAGQSAVYQASRVSAVSNSQHYP 1415
               +S  Y +S  S  + + H+P
Sbjct: 4548 LVEESTTYHSSPGS--TQTMHFP 4568



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 73/330 (22%), Positives = 129/330 (39%), Gaps = 38/330 (11%)

Query: 1102 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN 1161
            GS+ + +  G+    G S ++ +      SP  +++S     S   S  +++SH RP   
Sbjct: 4311 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPD-TTLSPASTTSSGVSEESTTSHSRPGSM 4369

Query: 1162 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL 1221
             ++ +  P+S        ++P V + S         SP          S  A   GPE+ 
Sbjct: 4370 HTTAF--PSST-------TMPGVSQESTA----SHSSPGSTDTTLSPGSTTASSLGPEST 4416

Query: 1222 SSALSKGAT---VYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTA 1278
            +   S G+T   +   +  +  LL+  +P   S      + SP      Q    ++++  
Sbjct: 4417 TFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 4476

Query: 1279 LRPGN---PPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNL 1335
                    PP+  S+   LS+TS+ SP+           T T  + +S    G S  S  
Sbjct: 4477 NSKDTTPAPPTTTSAFVELSTTSHGSPSS----------TPTTHFSASSTTLGRSEESTT 4526

Query: 1336 PRRSCPSSAASPTLQGPSDSPTSDSVSQSST-----GTLSSTSFPQNSRSSLPSDLRTIS 1390
               S  ++A +P+   P+ S TS  V +S+T     G+  +  FP+++ +S   +  T S
Sbjct: 4527 VHSSPVATATTPS---PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTS 4583

Query: 1391 LPSAGQSAVYQASRVSAVSNSQHYPHRGSG 1420
              S   +     S  SA+       H   G
Sbjct: 4584 HSSTTHTISSAPSTTSALVEEPTSYHSSPG 4613



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 81/368 (22%), Positives = 129/368 (35%), Gaps = 47/368 (12%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            ++  G  + + +  +S G+ Q      S T +   + S+    S+ H K S   ++ +  
Sbjct: 492  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 551

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQK------ 1194
                 S    T ++H R    IS R       E  +   S P  + ++V  A        
Sbjct: 552  HTSYHSSLGSTETTHFRDSSTISGR------SEESKASHSSPDAMATTVLPAGSTPSVLV 605

Query: 1195 GEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSL 1254
            G+ +P   S I+    +     G  T      K  T YS  R S       +  T S   
Sbjct: 606  GDSTP---SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR-SPDTTHLPASMTSSGVS 661

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAP- 1313
             + ++S  R   T +  +   TT   PG      +S SS   T  +      +  SL P 
Sbjct: 662  EESTTSHSRPGSTHTTAFPGSTT--MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE 719

Query: 1314 ---FTGTPGYFSSQPHSGNSTGSNLPRRSCP------------SSAASPTLQGPSDS--- 1355
               F   PG   +     N+T S L   S P            S A S T QG S +   
Sbjct: 720  YTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHS 779

Query: 1356 -PTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAG-------QSAVYQASRVSA 1407
             P+S     +   T S+   P  +    PS + T  + +         +S  Y +S  S 
Sbjct: 780  WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGS- 838

Query: 1408 VSNSQHYP 1415
             + + H+P
Sbjct: 839  -TQTMHFP 845



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 73/327 (22%), Positives = 122/327 (37%), Gaps = 55/327 (16%)

Query: 1096 SAGAGQGSSNSVSDTGAHGVQGSSARTPSS------PHKKFSPSHSSMSHLEA--VSPSD 1147
            +A  G+ S+   S +G+ G   S AR+ +S         + SPS +  + L     +PS 
Sbjct: 2934 TADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSL 2993

Query: 1148 SRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITE 1207
            S  +++ +  P+   ++     T+   + E         SS   +Q G    T       
Sbjct: 2994 SEKSTTFYTSPRSPDATLSPATTTSSGVSE--------ESSTSHSQPGSTHTT-----AF 3040

Query: 1208 KDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPT 1267
             DS    G   E  +S  S+G+T  + S           P + + S L Q S+ F   P 
Sbjct: 3041 PDSTTTSGLSQEPTASHSSQGSTEATLS-----------PGSTTASSLGQQSTTFHSSPG 3089

Query: 1268 QSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGY---FSSQ 1324
             +       T L P +  + G  E+S  + S +   H   T + +   G       F S 
Sbjct: 3090 DTE------TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 3143

Query: 1325 PHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTS--------------DSVSQSSTGTLS 1370
            P S ++T S     + P   ++     PS +PT+               +   SS G   
Sbjct: 3144 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203

Query: 1371 STSFPQNSRSSLPSDLRTISLPSAGQS 1397
            +  FP  S +S+     T S  S+G +
Sbjct: 3204 TALFPTRSATSVLVGEPTTSPISSGST 3230


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 65/286 (22%), Positives = 114/286 (39%), Gaps = 31/286 (10%)

Query: 286  LRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGN 345
            +R    L     IIEY G+V+  Q+F       ++ +     Y       M +D+   GN
Sbjct: 2154 IRTKEPLKAGQFIIEYLGEVVSEQEFR--NRMIEQYHNHSDHYCLNLDSGMVIDSYRMGN 2211

Query: 346  DARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACH 405
            +ARFI  SC PN E++    +G+  + +YA+  +    E+T  +DY + + N +    C 
Sbjct: 2212 EARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELT--YDYNFHSFNVEKQQLCK 2269

Query: 406  KGNRNC-----PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRK-ELEMEQQNEASE 459
             G   C        +R    T      P  +    G    +RK++ K +      +E   
Sbjct: 2270 CGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPS 2329

Query: 460  ENNDQQSQEVP----------EKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSR-- 507
            EN +  ++  P          E+  V   H  +    EK  +++EEV    +N+ HS   
Sbjct: 2330 ENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNI-HSASL 2388

Query: 508  --------RTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEI 545
                    R   + K +  M  F  L+  +  R + L  +  ++E+
Sbjct: 2389 YTRWNGICRDDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENIEV 2434



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 92/447 (20%), Positives = 146/447 (32%), Gaps = 66/447 (14%)

Query: 973  SDQAFRTEFNLMYAYSPLNAMPRADGLY-RGSPLVGDRKP-------------LHLDGGY 1018
            S   F   + + Y+ SPL A P   G Y R  P +    P             +H     
Sbjct: 1374 SSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSYMHAGHLL 1433

Query: 1019 CSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEA 1078
             +PA     +Y     K L + +           + + P  PP+     ++E++ R +  
Sbjct: 1434 LNPA-----KYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPPEMAYGWMVEHKHRHRHK 1488

Query: 1079 KENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMS 1138
                     +   S+        GSS SV ++      G  A      HK+    H S  
Sbjct: 1489 HR-------EHRSSEQPQVSMDTGSSRSVLESLKRYRFGKDAVGERYKHKEKHRCHMSCP 1541

Query: 1139 HLEAVSPSDSRGTSSSHCRPQENISSRWM--VPTSVERLREGGSIPKVLRSSVRVAQKGE 1196
            HL   SPS S            N   +W+   P+    L  G   P  +  S       E
Sbjct: 1542 HL---SPSKS----------LINREEQWVHREPSESSPLALGLQTPLQIDCS-------E 1581

Query: 1197 PSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQ 1256
             SP+        +S+PA  +    L ++      V +P+    + L  DSP   S     
Sbjct: 1582 SSPSLSLGGFTPNSEPASSDEHTNLFTSAIGSCRVSNPNSSGRKKL-TDSPGLFS----A 1636

Query: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFT- 1315
            Q +S  R H  +S   + R      G+ P+        S ++  SP    S+      T 
Sbjct: 1637 QDTSLNRLHRKESLPSNERAVQTLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTV 1696

Query: 1316 -GTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQG-----------PSDSPTSDSVSQ 1363
             G P        SG+ +  +L +R   +    P  +            PS SP       
Sbjct: 1697 NGVPSRSPRLVASGDDSVDSLLQRMVQNEDQEPMEKSIDAVIATASAPPSSSPGRSHSKD 1756

Query: 1364 SSTGTLSSTSFPQNSRSSLPSDLRTIS 1390
             + G   S   P  +  S  + +  +S
Sbjct: 1757 RTLGKPDSLLVPAVTSDSCNNSISLLS 1783


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 90/412 (21%), Positives = 145/412 (35%), Gaps = 15/412 (3%)

Query: 1015 DGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKR 1074
            D    S +   S+  +     D S  S S     + +   S+  +       S       
Sbjct: 652  DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 1075 KQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSH 1134
              ++ ++S     DS  S S  +     SS+S   + +     SS  + SS     S S 
Sbjct: 712  SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 1135 SSMSHLEAVSPSDSRGTS-SSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQ 1193
             S    ++ + SDS  +S SS      N S       S +      S       S   + 
Sbjct: 772  DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 1194 KGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCD-------- 1245
              + S + +S+ +   SD +D +      S+ S  ++  S S  S               
Sbjct: 832  SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 1246 ------SPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSY 1299
                  S  ++S S    +SS        S       ++    +  S  SS+SS SS S 
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951

Query: 1300 SSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSD 1359
            +S     S+DS      +    S    S NS+ S+    S  SS +S +      S +SD
Sbjct: 952  NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011

Query: 1360 SVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
            S   S++   S++S   NS  S  S   + S  S+  S    +S  S  S+S
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 80/338 (23%), Positives = 134/338 (39%), Gaps = 33/338 (9%)

Query: 1075 KQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSH 1134
            K ++ ++++    D++ S   S  +    S+  SD+        S+ +  S     S + 
Sbjct: 639  KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698

Query: 1135 SSMSHLEAVSPSDSRGTS-SSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQ 1193
            S  S     S SDS  +S SS+    ++ SS                      +S   + 
Sbjct: 699  SESSDSSDSSDSDSSDSSDSSNSNSSDSDSS----------------------NSSDSSD 736

Query: 1194 KGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQS 1253
                S + +S+ +   SD +D    ++ +S+ S  ++  S S  S       S  ++S  
Sbjct: 737  SSNSSDSSDSSDSSNSSDSSDSS--DSSNSSDSSDSSDSSDSSDS-------SNSSDSND 787

Query: 1254 LLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAP 1313
                S S    + + S   S  + +    +  S  SS+SS SS S  S     S+DS   
Sbjct: 788  SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847

Query: 1314 FTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTS 1373
              G+    S++  S NS+ S+    S  SS +S +      S +SDS S SS  + S +S
Sbjct: 848  SDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS-SDSSNSSDSDSS 906

Query: 1374 FPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
               NS  S  S   + S  S+  S    +S  S  S+S
Sbjct: 907  DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 76/337 (22%), Positives = 123/337 (36%), Gaps = 10/337 (2%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
            ++ ++ +    DS+ S   S  +    S+  SD+       SS R+ SS     S S  S
Sbjct: 814  DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 1137 MSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGE 1196
             +  ++   SDS  +S+S      + SS     +S        S       S   +   +
Sbjct: 874  SNSSDSSDSSDSNESSNSSDSSDSSNSSD--SDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 1197 PSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQ 1256
             S + +S+ +   SD +D       S++     +  S    S       +    S S   
Sbjct: 932  NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991

Query: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTG 1316
              SS        S       ++    +  S  SS+SS SS S  S     S+DS      
Sbjct: 992  SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS--- 1048

Query: 1317 TPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQ 1376
                 S    S NS+ S+    S  SS +S +      S +SDS   S++   S +S   
Sbjct: 1049 -----SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103

Query: 1377 NSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQH 1413
            +S  S  S   + S  S+  S    +S  S  S+S +
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 72/335 (21%), Positives = 129/335 (38%), Gaps = 19/335 (5%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
            E+K+N  G G DS  ++   + +   ++NS S+   +     + ++ S   K  S    S
Sbjct: 497  ESKDN--GNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDS 554

Query: 1137 MSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGE 1196
                 +   SDS  + SS      +  S            +  S       S   +   +
Sbjct: 555  SDSSNSSDSSDSSDSDSSDSNSSSDSDSS-----------DSDSSDSSDSDSSDSSNSSD 603

Query: 1197 PSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQ 1256
             S + +S+ +   SD +D +   + S + S  +   S S  S      +S  +   S   
Sbjct: 604  SSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS------NSSDSSDNSDSS 657

Query: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTG 1316
             SS+      +     S  +++    +  S  S  S  S++S SS +   S    +  + 
Sbjct: 658  DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717

Query: 1317 TPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQ 1376
            +    SS   S NS+ S+    S  SS +S +      S +SDS + S +   S +S   
Sbjct: 718  SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 1377 NSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
            +S +S  S+  + S  S+  S    +S  S  S+S
Sbjct: 778  DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 80/337 (23%), Positives = 125/337 (37%), Gaps = 6/337 (1%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            N +    DS+ S + S      SSNS   + +     SS  + SS +   S S +S    
Sbjct: 886  NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRS----SVRVAQKGE 1196
            ++   S+S  +S+S      + SS      S +      S      S    S   +   +
Sbjct: 946  DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005

Query: 1197 PSPTWESNITEKDSDPADGEGPETLS-SALSKGATVYSPSRYSYQLLQCDSPRTESQSLL 1255
             S + +S+ +   SD ++       S S+ S  ++  S S  S       +    S S  
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065

Query: 1256 QQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFT 1315
               SS        S       ++    +  S  SS+SS SS S  S     S+DS     
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125

Query: 1316 GTPGYFSSQPH-SGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSF 1374
             +    SS    S NS+ S+    S  SS +S +      S +SDS   S +   S +S 
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185

Query: 1375 PQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
              +S  S  S   + S  S+  S    +S  S  S+S
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 77/332 (23%), Positives = 124/332 (37%), Gaps = 10/332 (3%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            +++    DS+ S + S  +    S++ SD+       SS  + SS     S S  S    
Sbjct: 939  SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT 1200
            ++ + SDS  +S S      + SS     ++     +         SS   +   + S +
Sbjct: 999  DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDS-SDSSDSSNS 1057

Query: 1201 WESNITEKDSDPADG-EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSS 1259
             +S+ +   SD +D  +  ++  S+ S  ++  S S  S            S S     S
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 1260 SPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPG 1319
            S        S       ++    +  S  SSESS SS S  S     S+DS         
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS------ 1171

Query: 1320 YFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSR 1379
              S    S NS+ S+    S  SS +S +      S +SDS   S +   S +S   +S 
Sbjct: 1172 --SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229

Query: 1380 SSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
             S  S   + S  S+  S    +S  S  S+S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 76/340 (22%), Positives = 135/340 (39%), Gaps = 25/340 (7%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSAR-TPSSPHKKFSPSHS 1135
            +   +    G D A S+S +  + +G ++  SD       GS ++          S +++
Sbjct: 464  DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523

Query: 1136 SMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKG 1195
            S S+    + +D    S S     ++  S      S +      S      S    +   
Sbjct: 524  SDSNGNGNNGNDDNDKSDSGKGKSDSSDS-----DSSDSSNSSDS------SDSSDSDSS 572

Query: 1196 EPSPTWESNITEKDS-DPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSL 1254
            + + + +S+ ++ DS D +D +  ++ +S+ S  ++  S S  S       S  ++S+S 
Sbjct: 573  DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALRPGNPP-SHGSSESSLSSTSYSSPAHPVSTDSLAP 1313
               S S      + S   S  + +    N   S  SS+SS SS S SS     S+DS   
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS--- 689

Query: 1314 FTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTS 1373
                    S    S NS+ S+    S  S ++  +    S+S  SDS + S +   S++S
Sbjct: 690  --------SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 1374 FPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQH 1413
               +S  S  S   + S  S+  S    +S  S  S+S +
Sbjct: 742  DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 64/275 (23%), Positives = 100/275 (36%), Gaps = 4/275 (1%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            NS+     S  S S  +     SS+S + + +     SS  + SS     S S  S    
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT 1200
            ++ + SDS  +S S      + SS     +      +         SS   +   + S +
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS-SNSSDSSDS 1147

Query: 1201 WESNITEKDSDPADG-EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSS 1259
             ES+ +   SD +D  +  ++  S+ S  ++  S S  S            S S     S
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207

Query: 1260 SPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPG 1319
            S        S       ++    +  S  SS+SS SS S +S     S+DS    + +  
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267

Query: 1320 YFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSD 1354
               SQ  SGN  G+N    S   S  S +    SD
Sbjct: 1268 ESDSQSKSGN--GNNNGSDSDSDSEGSDSNHSTSD 1300



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 5/109 (4%)

Query: 454 QNEASEENNDQQSQEVPE-KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTRED 512
           QN  S+E  D + +E P  +V      +  +N    PE+   + I+D + L H    RE 
Sbjct: 297 QNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNH----RES 352

Query: 513 RKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTE 561
           ++VE  +          K +D+ +E           T E   G E K +
Sbjct: 353 KRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKED 401


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 85/341 (24%), Positives = 133/341 (39%), Gaps = 37/341 (10%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
            EA  +     G S  + + S G+   +S  VS T     + S+  T        + +H +
Sbjct: 724  EASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLD----TSTHIT 779

Query: 1137 MSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGE 1196
             S   + SP+ + GTS     P E       +P S+  +      P+    S        
Sbjct: 780  TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS----PEASTLSTTPVDSNS 835

Query: 1197 PSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQ 1256
            P  T     TE  S P   EG    +S  S+G T  +    S  L+   +  T S + + 
Sbjct: 836  PVTT----STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891

Query: 1257 QS-----SSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESS---LSSTSYSSPAHPVST 1308
             S     S+  R  PT S G S  T+    G+ P     +S+   +SS + +  A PV  
Sbjct: 892  TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVD- 950

Query: 1309 DSLAPFTGTPGYFSSQPHSGNST--GSNLPRRSCPSSAASPTLQGPSDSPTSDS-VSQSS 1365
                  T TP   S++  S  +T  G+++P  S PS   +P     + +P S + V+ S 
Sbjct: 951  ------TSTPVTTSTEATSSPTTAEGTSIP-TSTPSEGTTPL----TSTPVSHTLVANSE 999

Query: 1366 TGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVS 1406
              TLS+T  P +S + L +     S P   +      S  S
Sbjct: 1000 ASTLSTT--PVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 189/884 (21%), Positives = 305/884 (34%), Gaps = 117/884 (13%)

Query: 547  TTTSETPVGEETK--TEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPK 604
            +T S TPV   T   T +  S  S +    +IP++  S G     +              
Sbjct: 529  STLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAS 588

Query: 605  PPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGS 664
                 P+        S   +SS+   +      +  +E          S +LV  +EA +
Sbjct: 589  TTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST 648

Query: 665  LDSS--GENRPLTGS-DPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVEC 721
            L ++    N P+T S + T  S T    +   S Y +    L +            PV  
Sbjct: 649  LSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTS-----------MPVNT 697

Query: 722  PLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLP--DGTFSS 779
             L  +++ + L+TT    P    +P+  +T        SP   +    P     +G+   
Sbjct: 698  TLVASSEASTLSTT----PVDTSTPVTTSTEAS----SSPTTADGASMPTSTPSEGSTPL 749

Query: 780  CKKRWIKQALEEGMTQT-SSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRY 838
                  K  L      T S+ P +T T H+  S E S S +  +  +  +S   +     
Sbjct: 750  TSMPVSKTLLTSSEASTLSTTPLDTST-HITTSTEASCSPTTTEGTSMPISTPSEGSPL- 807

Query: 839  LMEQNVTKLLRPLSPVTPPPPNSGSKSP-------QLATPGSSHP----GEEECRNGYSL 887
                 +T +   ++PVT P  ++ S +P         +T  SS P    G     + YS 
Sbjct: 808  -----LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862

Query: 888  MFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPH 947
              +P+TS+        P+   L     +       +D++T        + NS  +  +P 
Sbjct: 863  GRTPLTSM--------PVSTTLVATSAISTLSTTPVDTST-------PVTNSTEARSSPT 907

Query: 948  PSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYR-GSPLV 1006
             S G +  T  P        ++  ++     +E   + A     + P         SP  
Sbjct: 908  TSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTT 967

Query: 1007 GDRKPLHLDGGYCSPAEGF----SSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQ 1062
             +   +       +P+EG     S+   H L+ +    +LS               N P 
Sbjct: 968  AEGTSIPTS----TPSEGTTPLTSTPVSHTLVANSEASTLS---------TTPVDSNTPL 1014

Query: 1063 RKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSART 1122
                          EA        G S  + + S G+   +   VS T     + S+  T
Sbjct: 1015 TTST----------EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLST 1064

Query: 1123 P----SSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG 1178
                 S+P   +S + SS +  +  S   S  +  S       +S+R +V +    L   
Sbjct: 1065 TPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTL--- 1121

Query: 1179 GSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYS 1238
             + P      V  + +   SPT     +   S P++G  P  L+S       V S    +
Sbjct: 1122 STTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP--LASMPVSTTLVVSSEANT 1179

Query: 1239 YQLLQCDSPRTESQSLLQQSSSP----FRGHPTQSPGYSYRTTALRPGNPPSHGSSESSL 1294
                  DS +T+  +  + SS P        PT +PG         P       SSE+S 
Sbjct: 1180 LSTTPVDS-KTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAST 1238

Query: 1295 SSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP-------SSAASP 1347
             STS    + PV+T +    + T    +S P S  S GS L   S P       S  AS 
Sbjct: 1239 LSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTL-LTSIPVSTTLVTSPEAST 1297

Query: 1348 TLQGPSDSP----TSDSVSQSST---GTLSSTSFPQNSRSSLPS 1384
             L  P D+     TS+ VS S T   GT   TS     R+ L S
Sbjct: 1298 LLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTS 1341



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 87/339 (25%), Positives = 131/339 (38%), Gaps = 33/339 (9%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTP----SSPHKKFSP 1132
            EA  +     G S  + + S G+   +S  VS T     + S+  T     S+P   +S 
Sbjct: 3258 EASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQ 3317

Query: 1133 SHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVA 1192
            + SS    +  S   S  +  S      + S+  +V +    L    + P    + V  +
Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL---STTPVDTSTPVTTS 3374

Query: 1193 QKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ 1252
             +   SPT     +   S P++G  P  L+S       V S    +      DS      
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTP--LASMPVSTTPVVSSEVNTLSTTPVDS------ 3426

Query: 1253 SLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSH---------GSSESSLSSTSYSSPA 1303
            + L  +S+     PT + G S  T+    G+ P            SSE+S  ST+    +
Sbjct: 3427 NTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTS 3486

Query: 1304 HPVSTDSLAPFTGTPGYFSSQPHSGNSTGS----NLPRRSCP--SSAASPTLQGPSDS-- 1355
             PV+T S    + T    +S P S    GS    N+P  + P  SS AS     P DS  
Sbjct: 3487 TPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNT 3546

Query: 1356 -PTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPS 1393
              TS S + SS  TL  T+   ++ S   S L T+ L S
Sbjct: 3547 FVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSS 3585



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 195/943 (20%), Positives = 323/943 (34%), Gaps = 140/943 (14%)

Query: 546  TTTTSETPVGEETKTEAPESE---VSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKL- 601
            T+T SE   G    T  P S    VS+  S ++      S+ V T   + +    AE   
Sbjct: 1093 TSTYSE---GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTS 1149

Query: 602  VPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTE 661
            +P  PP++ + P     +S     S++       AN        +  +   S    +P  
Sbjct: 1150 IPTSPPSEGTTPLASMPVSTTLVVSSE-------ANTLSTTPVDSKTQVATSTEASSPPP 1202

Query: 662  AGSLDSSGENRPLTGSDP-TVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVE 720
               + S   + P   S P T + +  + V  + +    T     +  +   AE    P  
Sbjct: 1203 TAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTT 1262

Query: 721  C-----PLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIP--ERRRRPLLP 773
                  P   T++ + L T++ +   L+ SP   T     +    P +   E    P   
Sbjct: 1263 AEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPA 1322

Query: 774  DGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNA-------D 826
            +GT              EG T  +S+P  T    L  S+  S  S+   DN+       +
Sbjct: 1323 EGTSMPTS------TYSEGRTPLTSIPVNTT---LVASSAISILSTTPVDNSTPVTTSTE 1373

Query: 827  LLSPLKKWKSRYLMEQNVTKLLRPLS--PVTPPPPNSGSKSPQLATP-GSSHPGEEECRN 883
              S     +   +   N ++   PL+  PV+  P  S   S   ATP  +S PG      
Sbjct: 1374 ACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEA 1433

Query: 884  GYSLMFSPVTSLTTA--SRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRP-----SL 936
              S   +   S+ T+  S   TPL       K + ++     +S  ++ +  P      +
Sbjct: 1434 TSSPTTAEGISIPTSTPSEGKTPL-------KSIPVSNTPVANSEASTLSTTPVDSNSPV 1486

Query: 937  LNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYA---------- 986
            + S     +P P+ G +     PS       ++  ++     +E N +            
Sbjct: 1487 VTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVT 1546

Query: 987  -YSPLNAMPR-ADGLYR--------GSPLVG----------------DRKPLHLDGGYCS 1020
             YS  ++ P  ADG            +PL                     P+       +
Sbjct: 1547 TYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTA 1606

Query: 1021 PAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVP--SAPQNPPQRKKVSLLEYRKRKQ-- 1076
              E  SS    G    +S  S    G      +P  + P   P+   +S           
Sbjct: 1607 STEASSSTTAEGSSMTISTPS---EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVI 1663

Query: 1077 ---EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTG-AHGVQGSSARTPSSPHKKFSP 1132
               E   +     G S  + + + G    +S +V  T  A     + + TP       + 
Sbjct: 1664 TSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723

Query: 1133 SHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVA 1192
            S  + S     SP+ S GTS  +  P E  +    +P S        + P +   +  ++
Sbjct: 1724 STEARS-----SPTTSEGTSMPNSTPSEGTTPLTSIPVS--------TTPVLSSEASTLS 1770

Query: 1193 QKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ 1252
                 + T  +  TE  S P   EG    +S LS+G T  + +  S+ L+      T S 
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLST 1830

Query: 1253 SLLQQ-----SSSPFRGHPTQSPGYSYRT-------TALR--PGNPPSHGSSESSLSSTS 1298
            + +       +S+     PT + G S  T       TAL   P +  +  SSE++  ST+
Sbjct: 1831 TPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTT 1890

Query: 1299 YSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAA----------SPT 1348
             +  + PV+T +    + T    SS P S    G   P  S P S            S T
Sbjct: 1891 PAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREG-RPPLTSIPVSTTTVASSEINTLSTT 1949

Query: 1349 LQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISL 1391
            L       T+ S + SS  T   TS P  + S   + L ++ L
Sbjct: 1950 LADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPL 1992



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 69/261 (26%), Positives = 103/261 (39%), Gaps = 33/261 (12%)

Query: 1144 SPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWES 1203
            SP+ S GTS     P E  +    +P S        ++P V   +  ++     + T  +
Sbjct: 2201 SPTTSEGTSMPTSTPSEGSTPFTSMPVS--------TMPVVTSEASTLSATPVDTSTPVT 2252

Query: 1204 NITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFR 1263
              TE  S P   EG    +S LS+G T  +    S+ L+      T S + +  S++PF 
Sbjct: 2253 TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVD-SNTPFT 2311

Query: 1264 ------GHPTQSPGYSYRTTALRPGNPPSH---------GSSESSLSSTSYSSPAHPVST 1308
                    P  + G S  T+    GN P            S E+S  ST+ +  + PV+T
Sbjct: 2312 TSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTT 2371

Query: 1309 DSLAPFTGTPGYFSSQPHSGNSTG---------SNLPRRSCPSSAASPTLQGPSDSPTSD 1359
             S A  + T    +S P S  S G         S +P  S  +S  S T    S   T+ 
Sbjct: 2372 YSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTS 2431

Query: 1360 SVSQSSTGTLSSTSFPQNSRS 1380
            + + SS  T   TS P +  S
Sbjct: 2432 TEASSSPTTAEGTSIPTSPPS 2452



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 74/282 (26%), Positives = 112/282 (39%), Gaps = 36/282 (12%)

Query: 1144 SPSDSRGTSSSHCRPQENIS--SRWMVPTSVERLREGGSI---PKVLRSSVRVAQKGEPS 1198
            SP+ + G+S     P E  +  +  +V T++    E  ++   P    + V  + +   S
Sbjct: 2673 SPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSS 2732

Query: 1199 PTWESNITEKDSDPADGEGP------ETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ 1252
            PT     + + S P+DG  P       TL  A S+ +TV      S   +    P T S 
Sbjct: 2733 PTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTV------STTAVDTSIPVTTST 2786

Query: 1253 SLLQQSSSPFRGH----PTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVST 1308
               + SSSP        PT +P  +       P N     SSE+   ST+    + PV+T
Sbjct: 2787 ---EASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTT 2843

Query: 1309 DSLAPFTGTPGYFSSQPHSGNSTGSNL---------PRRSCPSSAASPTLQGPSDSPTSD 1359
             + A  + T       P S  S GS L         P  S  +S  S T    S   T+ 
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903

Query: 1360 SVSQSSTGTLSSTSFPQNSRSSLPSDLRTI---SLPSAGQSA 1398
            +   SS  T   TS P ++ S + + L +I   ++P AG  A
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA 2945



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 81/331 (24%), Positives = 125/331 (37%), Gaps = 32/331 (9%)

Query: 1103 SSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENI 1162
            +S  V+     G   ++A   S P   +S   + ++ +   +       +S+H     + 
Sbjct: 2365 TSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDT 2424

Query: 1163 SSRWMVPTSVER-----LREGGSIPKVLRSSVRVAQKGEP---SPTWESNITEKDSDPAD 1214
            S+   V TS E        EG SIP    S         P   +P   S      + P D
Sbjct: 2425 STP--VTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVD 2482

Query: 1215 GEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSY 1274
               P T S+  S   T       +  ++   S  +E  +LL  +S P    P  SP  S 
Sbjct: 2483 TSTPMTTSTEASSSPTT------AEDIVVPISTASEGSTLL--TSIPVSTTPVASPEAST 2534

Query: 1275 RTTALRPGNPPSHGSSESSLSSTSYSSPAHPVST--DSLAPFTGTPGYFSSQPHSGNST- 1331
             +T     N P   S+E S S+TS    + P ST  +   P    P        S  ST 
Sbjct: 2535 LSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTL 2594

Query: 1332 -----GSNLPRRSCPSSAASPTLQGPSDSP--TSDSVSQSSTGTLSST----SFPQNSRS 1380
                  +++P  +   +++SPT    +  P  T   VS S T  L ST    S   ++ S
Sbjct: 2595 STTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLS 2654

Query: 1381 SLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
            + P D RT+   S G S+    +  S++  S
Sbjct: 2655 TTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS 2685



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 73/301 (24%), Positives = 114/301 (37%), Gaps = 24/301 (7%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
            EA  +     G      + S G+   +S  VS T     + S+  T  +P    SP  +S
Sbjct: 3023 EASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLST--TPVDSNSPVVTS 3080

Query: 1137 MSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGG-----SIPKVLRSSVRV 1191
                 + SP+ + GTS       E  +    VP S   +         + P    + V  
Sbjct: 3081 TE--VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTT 3138

Query: 1192 AQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTES 1251
            + +   SPT     +   S P++G  P T     +        S  S   +   +P T S
Sbjct: 3139 STEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTS 3198

Query: 1252 QSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSL 1311
                  +++     PT +P          P +     SSE+S+ ST+      PV  DS 
Sbjct: 3199 TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT------PV--DSN 3250

Query: 1312 APFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSS 1371
             P T +    SS P    + G+++P  S PS  ++P    P  + T   V+ S T TLS+
Sbjct: 3251 TPLTTSTEASSSPP---TAEGTSMP-TSTPSEGSTPLTSMPVSTTT---VASSETSTLST 3303

Query: 1372 T 1372
            T
Sbjct: 3304 T 3304



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 181/909 (19%), Positives = 299/909 (32%), Gaps = 122/909 (13%)

Query: 541  SDVEITTTTSETPVGEETKTEAPESEVS---NSVSNVTIPSTPQSVGVNTRRSSQ---AG 594
            SD    ++T  TP    T +E+     +   +S  + + P+TP+   V     S+   + 
Sbjct: 100  SDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISS 159

Query: 595  DIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSN 654
             +A     P P     +    K  +S   T+S Q          +   + ++   EG + 
Sbjct: 160  TMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQA--SSSPTTPESTTIPKSTNSEGSTP 217

Query: 655  SLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEK 714
                P     + SS     LT   P  +S T   ++  AS  P T +       N     
Sbjct: 218  LTSMPASTMKVASSEAITLLT--TPVEIS-TPVTISAQASSSPTTAEG--PSLSNSAPSG 272

Query: 715  QECPV-ECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLP 773
               P+   PL +    +  A+TL+  P   + P+I +T        SP   E      +P
Sbjct: 273  GSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS----SSPTTAEGTS---IP 325

Query: 774  DGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKK 833
              T++            EG T  +S P  T       ++E S+ S    D + L++   +
Sbjct: 326  TSTYT------------EGSTPLTSTPASTMP---VATSEMSTLSITPVDTSTLVTTSTE 370

Query: 834  WKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVT 893
              S     +  + L   LS  + P  N    +  +A+         E     ++     T
Sbjct: 371  PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVAS--------SEASTTSTIPVDSKT 422

Query: 894  SLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPT 953
             +TTAS                         S++ + A+  S+  S  S+ +   +  P 
Sbjct: 423  FVTTASEA-----------------------SSSPTTAEDTSIATSTPSEGSTPLTSMPV 459

Query: 954  SETGFPSRSGDGHQTLVRNSDQAFRT--EFNLMYAYSPLNAMPRADGLYRGSPLVG---D 1008
            S T   S       T   +S     T  E +     + +N+MP +      +PL      
Sbjct: 460  STTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVS 519

Query: 1009 RKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSL 1068
              P+              +        + S  S +P G       PS    P     VS 
Sbjct: 520  TMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST 579

Query: 1069 L------------------EYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDT 1110
                                +     EA  +S    G S  + + S      +S SVS T
Sbjct: 580  RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639

Query: 1111 GAHGVQGSSARTP----SSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRW 1166
                 + S+  T     ++P    + + SS +  E  S   S  T  S       +++  
Sbjct: 640  LVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTL 699

Query: 1167 MVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL----- 1221
            +  +    L    + P    + V  + +   SPT     +   S P++G  P T      
Sbjct: 700  VASSEASTL---STTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSK 756

Query: 1222 -----SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHP---------- 1266
                 S A +   T    S +     +     T ++      S+P  G P          
Sbjct: 757  TLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSIT 816

Query: 1267 -TQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVST--DSLAPFTGTPGYFSS 1323
               SP  S  +T     N P   S+E S S T     + P ST  +   P T  P   + 
Sbjct: 817  PVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTL 876

Query: 1324 QPHSGNSTGSNLP-RRSCPSSAASPTLQGPSDSP-TSDSVSQSSTGTLSSTSFPQNSRSS 1381
               S  ST S  P   S P + ++     P+ S  TS   S    G+   TS P ++   
Sbjct: 877  VATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPV 936

Query: 1382 LPSDLRTIS 1390
            + S+ RT+S
Sbjct: 937  VSSEARTLS 945



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 81/327 (24%), Positives = 127/327 (38%), Gaps = 32/327 (9%)

Query: 1092 SKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGT 1151
            +++ S+   +GSS ++S         +S    ++P      S  S + +++ SP  +   
Sbjct: 2079 TEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138

Query: 1152 SSSHCRPQENISSRWMVPTSVERLREGGSIP---KVLRSSVRVAQKGEP--SPTWESNIT 1206
             SS   P E  S +    T  +R     S+P    V+ SS        P  + T  +N T
Sbjct: 2139 VSSSPIPTEGTSMQ--TSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNST 2196

Query: 1207 EKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQS-----SSP 1261
            E  S P   EG    +S  S+G+T ++    S   +      T S + +  S     S+ 
Sbjct: 2197 EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTE 2256

Query: 1262 FRGHPTQSPGYSYRTTALRPGNPP------SH---GSSESSLSSTSYSSPAHPVSTDSLA 1312
                PT + G S  T+ L  G  P      SH    +SE S  ST+      P +T + A
Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEA 2316

Query: 1313 PFTGTPGYFSSQPHSGNSTGSNLPRRSCP----------SSAASPTLQGPSDSPTSDSVS 1362
                     +S P S +S G N P    P          +S  S T    S   T+ S +
Sbjct: 2317 SSPPPTAEGTSMPTSTSSEG-NTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQA 2375

Query: 1363 QSSTGTLSSTSFPQNSRSSLPSDLRTI 1389
             SS  T   TS P ++ S   + L ++
Sbjct: 2376 GSSPTTADDTSMPTSTYSEGSTPLTSV 2402



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 67/274 (24%), Positives = 107/274 (39%), Gaps = 25/274 (9%)

Query: 1144 SPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG-----GSIPKVLRSSVRVAQKGEPS 1198
            SP+ S GTS  +  P E  +    +P S   +         + P    +    + +   S
Sbjct: 1377 SPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSS 1436

Query: 1199 PTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQS 1258
            PT    I+   S P++G+ P       +        S  S   +  +SP   S + +  S
Sbjct: 1437 PTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTS-TAVSSS 1495

Query: 1259 SSPFRGHPTQSPGYSYRTTALR--PGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTG 1316
             +P  G        S  +TAL   P +  +  SSE +  ST+ +  + PV+T S A  + 
Sbjct: 1496 PTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSP 1555

Query: 1317 TPGYFSSQPHSGNSTGSNLPRRSCP-------SSAASPTLQGPSDSPT---------SDS 1360
            T    +S   S  S GS  P  S P       SS A+     P DS T         S +
Sbjct: 1556 TTADGTSMQTSTYSEGST-PLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSST 1614

Query: 1361 VSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA 1394
             ++ S+ T+S+ S      +S+P     ++ P A
Sbjct: 1615 TAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEA 1648



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 22/219 (10%)

Query: 1207 EKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRT------------ESQSL 1254
            E  S P   EG    +S  S+G+T+ +    S  L+      T             + + 
Sbjct: 1255 ETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNE 1314

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALR--PGNPPSHGSSESSLSSTSYSSPAHPVSTDSLA 1312
            +  S +P  G    +  YS   T L   P N     SS  S+ ST+    + PV+T + A
Sbjct: 1315 VSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEA 1374

Query: 1313 PFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSST 1372
              + T    +S P+S  S G+  P  S P S  +P +   + + ++  V  S+ GT S+ 
Sbjct: 1375 CSSPTTSEGTSMPNSNPSEGTT-PLTSIPVS-TTPVVSSEASTLSATPVDTSTPGTTSAE 1432

Query: 1373 SFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
            +      +S P+    IS+P++  S      +   VSN+
Sbjct: 1433 A------TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNT 1465



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 82/354 (23%), Positives = 136/354 (38%), Gaps = 55/354 (15%)

Query: 1085 GGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS-HSSMSHLEAV 1143
            GGG  +Q    +    Q S +  + + A+   G+++     P    S S +  M+ +E+ 
Sbjct: 38   GGGCISQGDVLNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESS 97

Query: 1144 SPSDSRGTSSSHCRPQEN-------ISSRWMVPTSVE-----RLREGGSIPKVLRSSVRV 1191
              SD+ G SS+   P E+         S  + P+S E        EG  +P    S   +
Sbjct: 98   VTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESI 157

Query: 1192 AQ-----KGEPSPTWE---------------SNITEKDSDPADGEGPETLSSALSKGATV 1231
            +         P P++E               +  T+  S P   E      S  S+G+T 
Sbjct: 158  SSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTP 217

Query: 1232 YSPSRYSYQLLQCDSPRTESQSLLQQS-----SSPFRGHPTQSPGYSYRTTALRPGNPPS 1286
             +    S   +      T   + ++ S     S+     PT + G S   +A   G+ P 
Sbjct: 218  LTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPL 277

Query: 1287 HG---------SSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPR 1337
                       SSE+S  ST+ ++   PV T + A  + T    +S P S  + GS  P 
Sbjct: 278  TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGST-PL 336

Query: 1338 RSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISL 1391
             S P+S    T+   +   ++ S++   T TL +TS      SSLP+     S+
Sbjct: 337  TSTPAS----TMPVATSEMSTLSITPVDTSTLVTTS---TEPSSLPTTAEATSM 383



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 86/367 (23%), Positives = 136/367 (37%), Gaps = 46/367 (12%)

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
            EA  +      +S  + + S G+   +S SVS       + S+  T  +P    +P  +S
Sbjct: 488  EASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLST--TPVDTSTPVTTS 545

Query: 1137 MSHLEAVSPSDS-RGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKG 1195
                EA S S +  GTS     P E  +    +P S   +        V   +   +   
Sbjct: 546  S---EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLV--------VSSEASTTSTTP 594

Query: 1196 EPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLL 1255
              S T+ +  +E  S     EG    +S  S+  T  +    S  L+      T S + +
Sbjct: 595  ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654

Query: 1256 QQS-----SSPFRGHPTQSPGYSYRTTALRPGNPPSHG---------SSESSLSSTSYSS 1301
              +     S+      T + G S  T+    G+ P            SSE+S  ST+   
Sbjct: 655  DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714

Query: 1302 PAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP-------SSAASPTLQGPSD 1354
             + PV+T + A  + T    +S P S  S GS  P  S P       SS AS     P D
Sbjct: 715  TSTPVTTSTEASSSPTTADGASMPTSTPSEGST-PLTSMPVSKTLLTSSEASTLSTTPLD 773

Query: 1355 SP---TSDSVSQSSTGTLSSTSFPQNSRS-------SLPSDLRTISLPSAGQSAVYQASR 1404
            +    T+ + +  S  T   TS P ++ S       S+P  +  ++ P A   +      
Sbjct: 774  TSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS 833

Query: 1405 VSAVSNS 1411
             S V+ S
Sbjct: 834  NSPVTTS 840



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 67/255 (26%), Positives = 98/255 (38%), Gaps = 22/255 (8%)

Query: 1144 SPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG-----GSIPKVLRSSVRVAQKGEPS 1198
            SP+ S GTS     P E  +    +P S   +         + P    + V  + +   S
Sbjct: 3145 SPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSS 3204

Query: 1199 PTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQS 1258
             T E   +   S P++G  P T     +        S  S   +  ++P T S    + S
Sbjct: 3205 TTAEGT-SIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST---EAS 3260

Query: 1259 SSPFRGH----PTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPF 1314
            SSP        PT +P          P +  +  SSE+S  ST+ +  + PV+T S A  
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320

Query: 1315 TGTPGYFSSQPHSGNSTGS----NLPRRSCP--SSAASPTLQGPSDSPTSDSVSQS---S 1365
            +      +S P S  S GS    N+   + P  SS AS     P D+ T  + S     S
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 1366 TGTLSSTSFPQNSRS 1380
              T   TS P +S S
Sbjct: 3381 PTTAEGTSIPTSSPS 3395



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 76/311 (24%), Positives = 114/311 (36%), Gaps = 41/311 (13%)

Query: 1099 AGQGSSN----SVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSS 1154
            AG+GS+      VS T     + S+  T       F  S S  S     SP+  + T+  
Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASS----SPATLQVTTMR 3567

Query: 1155 HCRPQENISSRWMVPTSVERLREGG----SIPKVLRSS-VRVAQKGEPSPTWESNITEKD 1209
               P E  SS   +  S   +        S P V RS+ V  + +   +PT    IT   
Sbjct: 3568 MSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPM 3627

Query: 1210 SDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQS 1269
            S P++   P T+    +   T+      S   +   +P   S    Q SSSP     T  
Sbjct: 3628 STPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITST---QVSSSPVTPEGTTM 3684

Query: 1270 PGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGN 1329
            P ++           PS GS+  +           PVST  +   T + G   S P    
Sbjct: 3685 PIWT-----------PSEGSTPLTTM---------PVSTTRV---TSSEGSTLSTPSVVT 3721

Query: 1330 STGSNLPRRSCPSSAA--SPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLR 1387
            ST       +  SSA   S T+        S   +     T   T FP++S  S+PS   
Sbjct: 3722 STPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781

Query: 1388 TISLPSAGQSA 1398
            ++S+ +A + +
Sbjct: 3782 SMSMTTASEGS 3792



 Score = 40.0 bits (92), Expect = 0.016
 Identities = 44/201 (21%), Positives = 79/201 (39%), Gaps = 10/201 (4%)

Query: 1207 EKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTES-----QSLLQQSSSP 1261
            +  S P   EGP   +SA S G+T  +    S  L+      T S      ++   +S+ 
Sbjct: 252  QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTE 311

Query: 1262 FRGHPTQSPGYSYRTTALRPGNPPSHGSSESSL---SSTSYSSPAHPVSTDSLAPFTGTP 1318
                PT + G S  T+    G+ P   +  S++   +S   +    PV T +L   +  P
Sbjct: 312  ASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEP 371

Query: 1319 GYFSSQPHSGNSTGSNLPRRSCP--SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQ 1376
                +   + +   S L   S P  +   S  L   S++ T+ ++   S   +++ S   
Sbjct: 372  SSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEAS 431

Query: 1377 NSRSSLPSDLRTISLPSAGQS 1397
            +S ++        S PS G +
Sbjct: 432  SSPTTAEDTSIATSTPSEGST 452



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 57/215 (26%), Positives = 89/215 (41%), Gaps = 26/215 (12%)

Query: 1189 VRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPR 1248
            V  + +G  SPT     +   S P++   P  L+S L     V      +      D+ R
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMPISTPSEVSTP--LTSILVSTVPVAGSEASTLSTTPVDT-R 2956

Query: 1249 TESQSLLQQSSSPFRGH----PTQSPGYSYRT--TALRPGNPPSHGSSESSLSSTSYSSP 1302
            T   +  + SSSP        P  +PG   RT  T++     P   S  S+LS T  +  
Sbjct: 2957 TPVTTSAEASSSPTTAEGTSMPISTPG-ERRTPLTSMSVSTMPVASSEASTLSRTP-ADT 3014

Query: 1303 AHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVS 1362
            + PV+T + A         SS P +   TG  +   S PS  ++P    P  S T  ++ 
Sbjct: 3015 STPVTTSTEA---------SSSPTTAEGTGIPI---STPSEGSTPLTSIPV-STTPVAIP 3061

Query: 1363 QSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQS 1397
            ++S  TLS+T    NS     +++ +   P+ G S
Sbjct: 3062 EAS--TLSTTPVDSNSPVVTSTEVSSSPTPAEGTS 3094


>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
          Length = 1352

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 106/387 (27%), Positives = 154/387 (39%), Gaps = 37/387 (9%)

Query: 1054 PSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGG-------DSAQSKSKSAGAGQGSSNS 1106
            P++  +    ++ SL    +  +   E S   GG        S Q +S S+ +   S  +
Sbjct: 798  PASVTSAASSRRTSLASLSESVEMTGERSEDDGGFSTRPFVRSVQRQSLSSRSSVTSPLA 857

Query: 1107 VSDTGAHGVQGSSARTP--SSPHKKFS---PSHSSMSHLEAVSPSDSRGTSSSHCRPQEN 1161
            V++         SA+    S+   +FS   P HSS S LE +  +     S S      N
Sbjct: 858  VNENCMRPSWSLSAKLQMRSNSPSRFSGDSPIHSSASTLEKIGEAADDKVSISCFGSLRN 917

Query: 1162 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSD---PADGEGP 1218
            +SS +  P+     RE  ++ +   + +    K E S T   N +  D+     A G+  
Sbjct: 918  LSSSYQEPSDSHSRREHKAVGRAPLAVMEGVFKDE-SDTRRLNSSVVDTQSKHSAQGDRL 976

Query: 1219 ETLSSALSKGATV----YSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSY 1274
              LS        +     S S  S  + +  +P +   SL ++  S  +  P+ S G S 
Sbjct: 977  PPLSGPFDNNNQIAYVDQSDSVDSSPVKEVKAP-SHPGSLAKKPESTTKRSPS-SKGTSE 1034

Query: 1275 RTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSN 1334
               +LR G  P+  S ESSLSSTS SSP  PV   SL P        SS   SG  +   
Sbjct: 1035 PEKSLRKGR-PALASQESSLSSTSPSSPL-PVKV-SLKPSRSRSKADSSSRGSGRHSS-- 1089

Query: 1335 LPRRSCPSSAASPTLQGPSDSPTSDSVSQSS--TGTLSSTSFPQNS----RSSLP---SD 1385
             P  + P   +SP  Q    SP+      +S  T T SSTS  + S    RS  P   S 
Sbjct: 1090 -PAPAQPKKESSPKSQDSVSSPSPQKQKSASALTYTASSTSAKKASGPATRSPFPPGKSR 1148

Query: 1386 LRTISLPSAGQSAVYQASRVSAVSNSQ 1412
                SL   G      + R SA S S+
Sbjct: 1149 TSDHSLSREGSRQSLGSDRASATSTSK 1175



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 82/310 (26%), Positives = 118/310 (38%), Gaps = 38/310 (12%)

Query: 1055 SAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDS----AQSKSKSAGAGQGSSNS---- 1106
            S   + P   KVSL   R R + A  +S G G  S    AQ K +S+   Q S +S    
Sbjct: 1055 STSPSSPLPVKVSLKPSRSRSK-ADSSSRGSGRHSSPAPAQPKKESSPKSQDSVSSPSPQ 1113

Query: 1107 -----------VSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSH 1155
                        S T A    G + R+P  P K  +  HS        S    R +++S 
Sbjct: 1114 KQKSASALTYTASSTSAKKASGPATRSPFPPGKSRTSDHSLSREGSRQSLGSDRASATST 1173

Query: 1156 CRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADG 1215
             +P    S R     S  R  EG    K +RSS  +A    PS + +S + ++DS   D 
Sbjct: 1174 SKPN---SPR----VSQARAGEGRGAGKHVRSS-SMASLRSPSTSIKSGL-KRDSKSED- 1223

Query: 1216 EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQS--SSPFRGH-PTQSPGY 1272
            +G     SAL +  T  S       LL   +  +  +S+ + +      RGH P  S   
Sbjct: 1224 KGLSFFKSALRQKETRRSTDLGKTALLSKKAGGSSVKSVCKNTGDDEAERGHQPPASQQP 1283

Query: 1273 SYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTG 1332
            +  TT           S++ SL S   S  +     DS  P   +PG   S   S     
Sbjct: 1284 NANTTGKEQLVTKDPASAKHSLLSARKSKSS---QLDSGVP--SSPGGRQSAEKSSKKLS 1338

Query: 1333 SNLPRRSCPS 1342
            S++   + PS
Sbjct: 1339 SSMQTSARPS 1348


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 56/250 (22%), Positives = 109/250 (43%), Gaps = 40/250 (16%)

Query: 422 ELPLLPPPPSLPTIGAETRRR-KARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHE 480
           +L +L   PS   I    R + + R KELE EQ+ E  +E    + ++  ++  +  + E
Sbjct: 491 KLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550

Query: 481 EVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSN 540
           +    E++ ++EKE+ ++ Q+      +  ++++ E        LEK +++ ++ +E   
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC------ELEKEREKLEEKIEPRE 604

Query: 541 SDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEK 600
            ++E        P+ E+ ++E       NS +    P       V TR+ S   +  A  
Sbjct: 605 PNLE--------PMVEKQESE-------NSCNKEEEP-------VFTRQDSNRSEKEATP 642

Query: 601 LVPKPPPAKPSRPRP-----------KSRISRYRTSSAQRLKRQKQANAQQAELSQAALE 649
           +V +  P   S+PRP           KS   R++    Q  ++Q Q   QQ  L Q    
Sbjct: 643 VVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPS 702

Query: 650 EGGSNSLVTP 659
           +  S+++  P
Sbjct: 703 QPSSSTVPPP 712



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 80/419 (19%), Positives = 147/419 (35%), Gaps = 40/419 (9%)

Query: 473  VTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRR 532
            V +  DH EV   E+      ++   +  +    +R ++              E+R+K+ 
Sbjct: 1657 VVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQD--------------EERRKKE 1702

Query: 533  DQPLE---QSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRR 589
            +Q ++   + N++ +  + TS+ P     K      +  +S S   + S P  +  +T  
Sbjct: 1703 EQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAP--LPPSTSA 1760

Query: 590  SSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALE 649
            S  A   A       P PA  S P P S ++    S++  +     A    +    A++ 
Sbjct: 1761 SVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVP 1820

Query: 650  EGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLN 709
               S + +T + A +  S+    P+  S  T  S+T      A++  P     L +    
Sbjct: 1821 ASTSAAAITSSSAPA--SAPAPTPILASVSTPASVT----ILASASIPILASALASTSAP 1874

Query: 710  DKAEKQECPVECPLRITTDPTVLAT-TLNMLPGLIHSPLICTTPKHYIRFGSPFIPERRR 768
              A     P    +   T P    T ++ + P    +P    TP          +     
Sbjct: 1875 TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP----------VSAPNP 1924

Query: 769  RPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNEN---SSSSSICKDNA 825
             P  P  T +   K  ++  L+     +   P   R       N     +S  SI    +
Sbjct: 1925 APPAPAQTQAQTHKP-VQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQS 1983

Query: 826  DLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNG 884
                  + W ++      +  + + L P++PP P S S   +  T   S P  E  +NG
Sbjct: 1984 HGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNG 2042



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 15/139 (10%)

Query: 1257 QSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSP-AHPVSTDSLAPFT 1315
            Q SS     P  +   +++  + R     S    E     TS + P A  VS+ +  P T
Sbjct: 2231 QQSSSLTSVPPTTFSLTFKMESARKAWENSPNVREKGSPVTSTAPPIATGVSSSASGPST 2290

Query: 1316 GTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFP 1375
                 FSS         +++P+    S   + +L G     TS   ++S+T     TS P
Sbjct: 2291 ANYNSFSS---------ASMPQIPVASVTPTASLSGAGTYTTSSLSTKSTT-----TSDP 2336

Query: 1376 QNSRSSLPSDLRTISLPSA 1394
             N     P  L+T SLPSA
Sbjct: 2337 PNICKVKPQQLQTSSLPSA 2355



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 13/125 (10%)

Query: 533 DQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGV------- 585
           D   + SNS  E  +    +   E  + +    EVSN+ S+  IP+ P    V       
Sbjct: 336 DDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPS 395

Query: 586 -NTRRSSQAGDIAAEKLVPK--PPPAKPSRP-RPKSRISRYRTSSAQRLKRQKQANAQQA 641
            N  R + +      KL+ +  PPP + + P RP    S+ + +    +   KQ   QQ+
Sbjct: 396 FNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEI--WKQRRRQQS 453

Query: 642 ELSQA 646
           E+S A
Sbjct: 454 EISAA 458



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 48/234 (20%), Positives = 80/234 (34%), Gaps = 31/234 (13%)

Query: 430  PSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEE-VDNPEEK 488
            P    I A   +   +R         +  +E   + S  +P+  +   D +E ++ PEEK
Sbjct: 907  PQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEK 966

Query: 489  PEEE----------KEEVIDDQENLAHSRRTREDRKVEAIMHAFEN--------LEKRKK 530
            P++E           E+V   +       R   +R+ E                L   K+
Sbjct: 967  PKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKE 1026

Query: 531  RRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRS 590
             R+Q  E+     E  T   E  V +  KTE  +            P  PQSV    +  
Sbjct: 1027 EREQRKEKEGEKAEKVT---EKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPE 1083

Query: 591  SQ---AGDIAAEKLVPKPPPAKPSRP------RPKSRISRYRTSSAQRLKRQKQ 635
            ++   + + A     P     KP  P       P  +    +T +A  +K +KQ
Sbjct: 1084 AEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQ 1137



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 72/331 (21%), Positives = 124/331 (37%), Gaps = 34/331 (10%)

Query: 1062 QRKKVSLLEYRKRKQEA----KENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQG 1117
            Q+K++   E RK++++      + +A   G S  SK     A + +      TG    Q 
Sbjct: 1689 QQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQA------TGIQQAQ- 1741

Query: 1118 SSARTPSSPHKKFSPSHSSM--SHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERL 1175
            SSA  P        PS S+   +   A  P+      +S   P   + +  + P      
Sbjct: 1742 SSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP---VPASTLAPVLASTS 1798

Query: 1176 REGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPS 1235
                + P    S+        P+ T  + IT   S PA    P  + +++S  A+V   +
Sbjct: 1799 APVPASPLAPVSASASVSASVPASTSAAAITSS-SAPASAPAPTPILASVSTPASVTILA 1857

Query: 1236 RYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLS 1295
              S  +L          S L  +S+P       SP     T    P + P+     +  S
Sbjct: 1858 SASIPILA---------SALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPAS 1908

Query: 1296 STSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDS 1355
            +++ +    PVS  + AP    P    +Q  +     + L   S  S    P+++ PS +
Sbjct: 1909 ASAPAPAPTPVSAPNPAP----PAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPS-A 1963

Query: 1356 PTSDSVSQSSTGTLSSTSFPQNSRSSLPSDL 1386
             T +     ++G   S   PQ S  +L ++L
Sbjct: 1964 QTPNGTDYVASG--KSIQTPQ-SHGTLTAEL 1991


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 4/136 (2%)

Query: 276  VTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVE 335
            V R   H + L   R++    ++IEY G V+   Q +    ++        +  + +  E
Sbjct: 3833 VYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSK-GIGCYMFRIDDSE 3891

Query: 336  MCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSN 395
            + VDA   GN ARFI  SC PN   R +  DG  H+ I+A+  I +  E+T  + +   +
Sbjct: 3892 V-VDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIED 3950

Query: 396  CNYKVDCACHKGNRNC 411
             + K+ C C  G + C
Sbjct: 3951 ASNKLPCNC--GAKKC 3964


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 100/345 (28%), Positives = 134/345 (38%), Gaps = 53/345 (15%)

Query: 1091 QSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRG 1150
            Q  + + GA   S  S    GA G   S+A   S     FSP +S        SP  S G
Sbjct: 1522 QGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASG----FSPGYSPAWSPTPGSPG-SPG 1576

Query: 1151 TSSSHCRPQENISSRWMVPTS--VERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEK 1208
             SS +        S    PTS   E    GG  P+    S         SP++    T  
Sbjct: 1577 PSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSP--TSP 1634

Query: 1209 DSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFR-GHPT 1267
            +  P       T S + S  +  YSP+  SY      SP + S S    S SP    +  
Sbjct: 1635 NYSPTSPSYSPT-SPSYSPTSPSYSPTSPSY------SPTSPSYSPTSPSYSPTSPSYSP 1687

Query: 1268 QSPGYSYRTTALRPGNP------PSHGSSESSLSSTSYS----SPAHPVSTDSLAP---- 1313
             SP YS  + +  P +P      PS+  +  S S TS S    SP++  ++ S +P    
Sbjct: 1688 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPN 1747

Query: 1314 -------FTGTPGYFSSQPHSGNSTGSNL----PRRSCPSSAASPTLQGPSDSPTSDSVS 1362
                   +T T   +S    S + T  N     P  S  S + SPT   PS SPTS S S
Sbjct: 1748 YSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT--SPSYSPTSPSYS 1805

Query: 1363 --------QSSTGTLSSTSFPQNSRSSLPSDLR-TISLPSAGQSA 1398
                    QS T T SS S+  +S S  P+  + T + PS   S+
Sbjct: 1806 PSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSS 1850



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 94/374 (25%), Positives = 136/374 (36%), Gaps = 39/374 (10%)

Query: 1043 SPGGERACEGVPSAPQNP-------PQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSK 1095
            SPG   A    P +P +P       P         Y       +  S GG    + S S 
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSP 1617

Query: 1096 SAGAGQGSSNSVSDTGAHGVQGSSARTPSSP-HKKFSPSHSSMS-HLEAVSPSDSRGTSS 1153
            ++ +   +S S S T  +    S + +P+SP +   SPS+S  S      SPS S  + S
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1677

Query: 1154 -SHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEP-----SPTWESNITE 1207
             S   P  + +S    PTS        S      S    +    P     SPT  S    
Sbjct: 1678 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1737

Query: 1208 KDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCD---------------SPRTESQ 1252
              S           S   +  +  YSP+  SY     +               SP + S 
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSY 1797

Query: 1253 SLLQQSSSPFRGHPT-QSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSL 1311
            S    S SP     T QSP Y+  + +  P +P    +S     ++   SP+ P  T + 
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS 1857

Query: 1312 APFTGT-PGYFSSQPH---SGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTG 1367
              ++ T P Y  + P    +  +     P+ S  S   SPT   P  +PTS   S +S  
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPT--SPVYTPTSPKYSPTSP- 1914

Query: 1368 TLSSTSFPQNSRSS 1381
            T S TS P+ S +S
Sbjct: 1915 TYSPTS-PKYSPTS 1927



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 82/307 (26%), Positives = 122/307 (39%), Gaps = 22/307 (7%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSP-HKKFSPSHSSMS-HLEAVSPS 1146
            ++ S S ++ +   +S S S T       S + +P+SP +   SPS+S  S      SPS
Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1712

Query: 1147 DSRGTSS-SHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEP-SPTWESN 1204
             S  + S S   P  + +S    PTS        +      +    +    P SP++   
Sbjct: 1713 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSP- 1771

Query: 1205 ITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRG 1264
             T  +  P       T S + S  +  YSP+  SY      SPR   QS     SSP   
Sbjct: 1772 -TSPNYTPTSPNYSPT-SPSYSPTSPSYSPTSPSYSP---SSPRYTPQSPTYTPSSP--S 1824

Query: 1265 HPTQSPGYSYRTTALRPGNPP-SHGSSESSLSSTSYS------SPAHPVSTDSLAPFTGT 1317
            +   SP YS  +    P +P  S  S E + +S  YS      SP  P  + +   ++ T
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884

Query: 1318 PGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQ--GPSDSPTSDSVSQSS-TGTLSSTSF 1374
               +S    + + T       S   S  SPT     P  SPTS + S +S  G+  S + 
Sbjct: 1885 TPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTS 1944

Query: 1375 PQNSRSS 1381
            P  S +S
Sbjct: 1945 PGYSPTS 1951



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 76/304 (25%), Positives = 114/304 (37%), Gaps = 22/304 (7%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSP-HKKFSPSHSSMS-HLEAVSPS 1146
            ++ S S ++ +   +S S S T       S + +P+SP +   SPS+S  S      SPS
Sbjct: 1674 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1733

Query: 1147 DSRGTSS-SHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNI 1205
             S  + S S   P  + +S    PTS        S      +    +    P+    S  
Sbjct: 1734 YSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT 1793

Query: 1206 TEKDSDPADGEGPET-----LSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSS 1260
            +   S  +    P +      S   +  +  YSPS  SY      SP+    S     SS
Sbjct: 1794 SPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPT---SPKYTPTSPSYSPSS 1850

Query: 1261 PFRGHPTQSPGYSYRTTALRPGNP------PSHGSSESSLSSTSYS-SPAHPVSTDSLAP 1313
            P   +   SP YS  +    P +P      P++  +    S TS + SP  PV T +   
Sbjct: 1851 P--EYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPK 1908

Query: 1314 FTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTS 1373
            ++ T   +S      + T       S   S  SPT   P  SPTS + S +S       S
Sbjct: 1909 YSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPT--SPGYSPTSPTYSLTSPAISPDDS 1966

Query: 1374 FPQN 1377
              +N
Sbjct: 1967 DEEN 1970


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 222/1087 (20%), Positives = 375/1087 (34%), Gaps = 209/1087 (19%)

Query: 414  QKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPEKV 473
            QKR+ N T       P   PT  ++T   K+     +  +    SEEN+  Q ++   + 
Sbjct: 145  QKRHCNTTRHS---KPTDKPTGNSKTIDHKS---STDNHEAPPTSEENSSNQGKDPMIRN 198

Query: 474  TVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRD 533
              S D  +      K    K+ +    ++  + R++   +           + ++  +  
Sbjct: 199  QRSVDPAD-STTTHKESAGKKHITPAPKSKINCRKSTTGKST---------VTRKSDKTG 248

Query: 534  QPLEQSNSDVEITTTTSETPV-------GEETK---TEAPESEVSNSVSNVTIPSTPQSV 583
            +PLE+S S ++ T+T+S             +TK   T  PE   + S +      TP+  
Sbjct: 249  RPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE- 307

Query: 584  GVNTRRSSQAGDIAAEKLVPK----------------------------------PPPAK 609
              + +       +A++KL+ K                                  P PA+
Sbjct: 308  --SEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 365

Query: 610  PSRPRPKSRISRYRTSSAQRLK-RQKQANAQQAELSQAALE--EGGSNSLVT-----PTE 661
            P+  R ++       S A+  + R++ AN   A       E  E  +N   T     PTE
Sbjct: 366  PTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTE 425

Query: 662  AGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK-----AEKQE 716
             G   ++ EN   + ++PT      ++ N   S    T+    T + NDK     AE  E
Sbjct: 426  HGE-RTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTE 484

Query: 717  CPVECPL-RITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIP-ERRRRPLLPD 774
                 PL    T P+    T N       +    TTP       SP  P E R       
Sbjct: 485  HGERTPLANENTTPSPAEPTENRERTANEN----TTP-------SPAGPTENRETTANEK 533

Query: 775  GTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKW 834
             T S  +    ++      T  S        Q    +NE ++SSS         +PL   
Sbjct: 534  TTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANE 593

Query: 835  KSRYLMEQNVTKLLRPLSPVTPP----PPNSGSKSP---QLATPGSSHPGEEECRNGYSL 887
             +     +      R  +  T P    P  +G ++P   +  TP  + P E   R     
Sbjct: 594  NTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQR----- 648

Query: 888  MFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPH 947
              +P  +  T S    P +    H +   LA      S      +R    N    +  P 
Sbjct: 649  --TPFANEKTTSSSAEPTE----HEERTPLANENTTPSPAEPTENRERTAN---ENTTPS 699

Query: 948  PSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLV- 1006
            P+ GPT                  N +     +  L  A    N    A+     SP   
Sbjct: 700  PA-GPT-----------------ENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEP 741

Query: 1007 ---GDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLS--RGSLSPGG------ERACEGVPS 1055
               G R P   +    S AE      EHG    L+    +LSP G        A E    
Sbjct: 742  TENGQRTPFANEKTTSSSAE----PTEHGERTPLANENTTLSPAGPTENRERTANEKTTP 797

Query: 1056 APQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGV 1115
             P  P +           R++ A EN+        ++  ++  A + ++ S+++   +G 
Sbjct: 798  FPAEPTE----------NRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENG- 846

Query: 1116 QGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERL 1175
                 RTP +  K  S S     H E  +P  +  T+SS   P EN        T+ E+ 
Sbjct: 847  ----KRTPFANEKTTSSSAEPTEHAER-TPLANENTTSSPAEPTENRER-----TANEKT 896

Query: 1176 REGGSIPKVLRSSVRVAQKGEPSP---------TWESNITEKDSDPADGEG------PET 1220
             +  + P   R S    +K  P P         T   N T   ++P + E        E 
Sbjct: 897  TQFPAEPTENREST-ANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDEN 955

Query: 1221 LSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALR 1280
            L +   +G+    P      +       + + S +  SS       T S   +  +TA  
Sbjct: 956  LQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSS-------TMSVSATASSTASS 1008

Query: 1281 PGNPPSHGSSESSLSSTSY------SSPAHPVSTDSLA----------PFTGTPGYFSSQ 1324
              +  +  S+   +SST+Y      ++ + PV+   LA            T T    +S 
Sbjct: 1009 TASEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSV 1068

Query: 1325 PHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPS 1384
            P + +++GS     +C ++ +  T+   + S   D+   + T  +++ S P ++ +  P+
Sbjct: 1069 PTTASTSGSK-NTTACEATMSETTIAAITAS--EDTTVSTQTSVIAAESVP-HTATKTPT 1124

Query: 1385 DLRTISL 1391
            D  T S+
Sbjct: 1125 DTTTASV 1131



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 202/1027 (19%), Positives = 348/1027 (33%), Gaps = 134/1027 (13%)

Query: 428  PPPSLPTIGAETRRRKARRKE-LEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPE 486
            P P+ PT   E R R A     L   +  E  E   ++ +   P   T + +    +N  
Sbjct: 361  PSPAEPT---ENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTT 417

Query: 487  ---EKPEEEKEEVIDDQ------ENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLE 537
                +P E  E   ++       E   H  RT  +    +     E+ E+     D+   
Sbjct: 418  LFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKT-- 475

Query: 538  QSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIA 597
             ++S  E T     TP+  E  T +P     N        +TP   G    R + A +  
Sbjct: 476  -TSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKT 534

Query: 598  AEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRL---KRQKQANAQQAELSQAALEEGGSN 654
                     P +P+  R  +   +   S A+     +R   AN +    S    E G   
Sbjct: 535  TLS------PVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERT 588

Query: 655  SLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVN--RAASKYPKTKKYLV-------- 704
             L       S     ENR  T ++ T  S      N  R      KT   L         
Sbjct: 589  PLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQR 648

Query: 705  TEWLNDK-----AEKQECPVECPL-RITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRF 758
            T + N+K     AE  E     PL    T P+    T N       +    TTP      
Sbjct: 649  TPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN----TTP------ 698

Query: 759  GSPFIPERRRRPLLPDGT--FSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSS 816
             SP  P   R     + T  F +      ++   E  T + + P E   +  + + + +S
Sbjct: 699  -SPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTS 757

Query: 817  SSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHP 876
            SS+          P +  +   L  +N T     LSP   P  N    + +  TP  + P
Sbjct: 758  SSA---------EPTEHGERTPLANENTT-----LSP-AGPTENRERTANEKTTPFPAEP 802

Query: 877  GEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADRPSL 936
             E   R   +   +P  +  T +   TPL  E       +  + G      N      S 
Sbjct: 803  TENRERTA-NENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSA 861

Query: 937  LNSGHSDLAPHPSLGPTSETGFPSRSGD---GHQTLVRNSDQAFRTEFNLMYAYSPLNAM 993
              + H++  P  +   TS    P+ + +     +T    ++     E       +P  A 
Sbjct: 862  EPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAE 921

Query: 994  PRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKD------LSRGSLSPGGE 1047
            P  +  +  +           +    SPAE         LM D        +GS +   +
Sbjct: 922  PTENREWTAN-----------ENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPK 970

Query: 1048 RACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSV 1107
              C  V S                        E+S      ++ + S SA A   +S++ 
Sbjct: 971  DICATVAST--------------------TGSESSTASEIITSSTMSVSATASSTASSTA 1010

Query: 1108 SD----TGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEA----VSPSDSRGTSSSHCRPQ 1159
            S+    + A  V  ++  T         P  +S+  LE+     + S++  +S+    P 
Sbjct: 1011 SEITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPT 1070

Query: 1160 ENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPE 1219
               +S     T+ E      +I  +  S        + + + ++++   +S P       
Sbjct: 1071 TASTSGSKNTTACEATMSETTIAAITASE-------DTTVSTQTSVIAAESVPHTATKTP 1123

Query: 1220 TLSSALSKGATVYSPSRYS-YQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTA 1278
            T ++  S  ATV   +  S        +P T S+++   S +      T  P   + TT+
Sbjct: 1124 TDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTS 1183

Query: 1279 -LRPGNP-PSHGSSESSLSSTSYSSPAHPV-STDSLAPFTGTPGYFSSQPHSGNSTGSNL 1335
             +  G+  P+  +++S+ ++ S  +    V S  S AP T      +S P + ++TGS  
Sbjct: 1184 KITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSEN 1243

Query: 1336 PRRSCPSSAASPTLQGPSDSPTSDSVSQSSTG-----TLSSTSFPQNSRSSLPSDLRTIS 1390
                  SS  +      S+S T    +++ST      T  +T+    S +++ S    ++
Sbjct: 1244 TGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVT 1303

Query: 1391 LPSAGQS 1397
               +G S
Sbjct: 1304 TTQSGFS 1310



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 77/342 (22%), Positives = 114/342 (33%), Gaps = 52/342 (15%)

Query: 412 PIQKRNPNATELPLLPPPPSLPTIGAETRRRKARRKELEMEQQNEASEENNDQQSQEVPE 471
           P + R   A E   L P    PT   ET          E    + A    N Q++    E
Sbjct: 522 PTENRETTANEKTTLSPVE--PTENRETTAN-------EKTTPSPAEPTENGQRTPFANE 572

Query: 472 KVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTREDRKVEAIMHAFEN------- 524
           K T SS  E  ++ E  P   +       E   +  RT  ++   +     EN       
Sbjct: 573 KTT-SSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLA 631

Query: 525 LEKRKKRRDQPLEQ-----------SNSDVEITTTTSETPVGEETKTEAPESEVSNSVSN 573
            EK      +P E            ++S  E T     TP+  E  T +P     N    
Sbjct: 632 NEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERT 691

Query: 574 VTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQ 633
               +TP   G    R   A +           PA+P+  R ++   +  +S A+  +  
Sbjct: 692 ANENTTPSPAGPTENREMTANEKTTLF------PAEPTENRERTANEKTTSSPAEPTE-- 743

Query: 634 KQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAA 693
              N Q+   +     E  ++S   PTE       GE  PL  ++ T +S  G   NR  
Sbjct: 744 ---NGQRTPFA----NEKTTSSSAEPTE------HGERTPL-ANENTTLSPAGPTENRER 789

Query: 694 SKYPKTKKYLVTEWLNDKAEKQECPVECPLRITT--DPTVLA 733
           +   KT  +      N +    E     P + T   D T LA
Sbjct: 790 TANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLA 831


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 63/267 (23%), Positives = 119/267 (44%), Gaps = 42/267 (15%)

Query: 155  HTPTSITLTVRRTKPKKRKKSPEKGRAA-----PKTKKIKNS-----PSEAQNLDENTTE 204
            HT T++T   R+ +P+   +  + G A      P +KK K+      P  A+ L+   T+
Sbjct: 1468 HTITNLTTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGVDTQ 1527

Query: 205  GWENRIRLWTDQYEEAFTNQYSADVQNALEQHLHSSKEFVGKPTILDTINKTELACNNTV 264
            G                TN+  ++ ++   + L +    +G   I+D+    +L   N +
Sbjct: 1528 G----------------TNRVLSERRSEQRRLLSA----IGTSAIMDS----DLLKLNQL 1563

Query: 265  IGSQMQLQLGRVTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPF 324
               + +L+ GR +R+  H   L A   +A D ++IEY G+ + +   ++    + +    
Sbjct: 1564 KFRKKKLRFGR-SRI--HEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIG 1620

Query: 325  VLFYSKFNGVEMCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAE 384
              +  + +  +  +DA   GN ARFI   CTPN   + +  +    + IY+   I  D E
Sbjct: 1621 SSYLFRVDH-DTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEE 1679

Query: 385  VTIAFDYEYSNCNYKVDCACHKGNRNC 411
            +T  +DY++   + K+ C C  G  +C
Sbjct: 1680 IT--YDYKFPLEDNKIPCLC--GTESC 1702



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 73/298 (24%), Positives = 110/298 (36%), Gaps = 33/298 (11%)

Query: 1086 GGDSAQSKSKSAGAG----QGSSNSVSDTGAH-------GVQGSSARTPSSPHKKFSPSH 1134
            GG +   K + +GA     +    S SDT A+       G  G+   TP S    FS S 
Sbjct: 196  GGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNG--TPCSQDTSFSSSR 253

Query: 1135 SSM-SHLEAVSPSDSRGT--SSSHCRP--QENISSRWMVPTSVERLREGGSIPKVLRSSV 1189
                S     +P  S+GT  +S    P  Q++  S     TS +  R   S       S 
Sbjct: 254  QDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAF--SR 311

Query: 1190 RVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRT 1249
            R       S T  + I    +  A        SS+LS  ++  S S  S Q    D+   
Sbjct: 312  RHFSASSASTTASTAIAATTAATASSSAS---SSSLSSSSSSSSSSSSS-QFRSSDA--- 364

Query: 1250 ESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSS-TSY--SSPAHPV 1306
             +     +S + ++ H +  P  + R     PG P +  ++E    S TSY    P+ P 
Sbjct: 365  -NYPAYYESWNRYQRHTSYPPRRATREEP--PGAPFAENTAERFPPSYTSYLPPEPSRPT 421

Query: 1307 STDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQS 1364
              D   P +  P     +P  G   G   P R    ++  P     S SP  ++ ++S
Sbjct: 422  DQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNES 479



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 41/202 (20%), Positives = 85/202 (42%), Gaps = 25/202 (12%)

Query: 440  RRRKARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDD 499
            +R + R K     +++ A +   ++ SQE       SS+ +E D+ E++ +E++EE +D 
Sbjct: 943  KRDEERGKTQGKHRKSFALDSEGEEASQES------SSEKDEEDDEEDEEDEDREEAVDT 996

Query: 500  QENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETK 559
                     T+++ +V       +  ++      +    ++SD E  +T+        + 
Sbjct: 997  ---------TKKETEVS------DGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSS 1041

Query: 560  TEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRI 619
            + +  S  S+S S+ +  S+ +      R ++        + VP P PA    P P+   
Sbjct: 1042 SSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPE--- 1098

Query: 620  SRYRTSSAQRLKRQKQANAQQA 641
             R   S    L  Q+ + A+ A
Sbjct: 1099 -RVAGSPVTPLPEQEASPARPA 1119



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 44/196 (22%), Positives = 70/196 (35%), Gaps = 27/196 (13%)

Query: 443  KARRKELEMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEE------KPEEEK--- 493
            K +RKE    + +EASEE   + S    E        +E   P        K +EE+   
Sbjct: 894  KVKRKE--PSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKT 951

Query: 494  --------------EEVIDDQENLAHSRRTREDRKVEAIMHAFENLEKRKKRRDQPLEQS 539
                          EE   +  +        ED + E    A +  +K  +  D   E+S
Sbjct: 952  QGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEES 1011

Query: 540  NSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAE 599
            +S  + +        GE   T   ES  S+S S+ +  S+  S   ++  SS   +   E
Sbjct: 1012 DSSSKCSLYADSD--GENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEE 1069

Query: 600  KLVPKPPPAKPSRPRP 615
            +    P  + P R  P
Sbjct: 1070 RPAALPSASPPPREVP 1085



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 87/425 (20%), Positives = 149/425 (35%), Gaps = 45/425 (10%)

Query: 450  EMEQQNEASEENNDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRT 509
            + + +N+++ ++    S       + SS      +  E   E++EE   ++   A    +
Sbjct: 1022 DSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEE---EERPAALPSAS 1078

Query: 510  REDRKVEAIMHAFENLEKRKKRRDQPL----EQSNSDVEITTTTSETPVGEETKT-EAPE 564
               R+V     A   +   ++    P+    EQ  S       T E+P     +  E P 
Sbjct: 1079 PPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPA 1138

Query: 565  SEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVP--KPPPAKPSRPRPKSRISRY 622
               + +      PS+P  +    ++  +    +A ++VP  +PPPA P + +     SR 
Sbjct: 1139 GPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRK 1198

Query: 623  RTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVV 682
                 +R  R    +   A L ++  EE            G L    E  P T  D  V+
Sbjct: 1199 APRGVERTIRNLPLD--HASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVL 1256

Query: 683  S-ITGSHVNRAASKYPKTKKYLVTEWLNDKAEK-----QECPVECPLRITTDPTVLATTL 736
            + +  +   R     P  +    TE  +D+AE+         +E    +   PT  A  L
Sbjct: 1257 ADLALTPARRGLPALPAVEDSEATE-TSDEAERPRPLLSHILLEHNYALAVKPTPPAPAL 1315

Query: 737  NMLPGLIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEEGMTQT 796
               P  + +P           F SP   E    P +        K + ++Q  EEG    
Sbjct: 1316 RP-PEPVPAPAAL--------FSSP-ADEVLEAPEVVVAEAEEPKPQQLQQQREEG---- 1361

Query: 797  SSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPVTP 856
                +E   +   +  E SS SS   D    L        R    ++  +  RP  P  P
Sbjct: 1362 ----EEEGEEEGEEEEEESSDSSSSSDGEGAL--------RRRSLRSHARRRRPPPPPPP 1409

Query: 857  PPPNS 861
            PPP +
Sbjct: 1410 PPPRA 1414



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 42/156 (26%), Positives = 64/156 (41%), Gaps = 20/156 (12%)

Query: 1246 SPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTAL-RPGN--PPSHGSSESSLSS------ 1296
            S + +      +++   R   + +  Y   TTA+  PGN  P S  +S SS         
Sbjct: 201  SEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSF 260

Query: 1297 ---TSYSSPAHPVSTDSLAPFTGTPGYFSSQP-------HSGNSTGSNLPRRSCPSSAAS 1346
               T  SS   P ++    P++    Y SS          S NS      RR   +S+AS
Sbjct: 261  GQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDAFSRRHFSASSAS 320

Query: 1347 PTLQGPSDSPTSDSVSQS-STGTLSSTSFPQNSRSS 1381
             T      + T+ + S S S+ +LSS+S   +S SS
Sbjct: 321  TTASTAIAATTAATASSSASSSSLSSSSSSSSSSSS 356


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 91/342 (26%), Positives = 138/342 (40%), Gaps = 37/342 (10%)

Query: 1106 SVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSD-SRGTSSSHCRPQENISS 1164
            ++S  G+   QG S    S P  K +      +    V PS  S G+ SS   P  +IS+
Sbjct: 248  TLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI--PTTHISA 305

Query: 1165 RWMVPTSVERLREGGSIPKVLRS-----SVRVAQKGEPSPTWESNITEKDSDPADG---- 1215
            R      VE      S P   ++     S   + +GE S T  S+ T   S         
Sbjct: 306  RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 365

Query: 1216 -EGPETLSSALSKGATVYSP-----SRYSYQLLQCDSPRTESQSLL---QQSSSPFRGHP 1266
             E P +  S+    AT + P     S  S +     S +  + +++   + ++S   G  
Sbjct: 366  VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 425

Query: 1267 TQSP--GYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQ 1324
            T SP    S  TTAL PG+  + G SE S  +T +SSP  P +T  L+P + T    S +
Sbjct: 426  TTSPISSGSMETTAL-PGSTTTPGLSERS--TTFHSSPRSPATT--LSPASTTSSGVSEE 480

Query: 1325 PHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPS 1384
              +  S   +    + P S  +P L   S      + S SS G+  +T  P ++ +S PS
Sbjct: 481  STTSRSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTTSGPS 534

Query: 1385 DLRTISLPSAGQS-AVYQASRVSAVSNSQHYP--HRGSGGVH 1423
               T S  S+G +         +A+S  Q     H   G  H
Sbjct: 535  QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 576



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 154/663 (23%), Positives = 236/663 (35%), Gaps = 117/663 (17%)

Query: 789  LEEGMTQTSSVPQETRTQHLYQSNE---NSSSSSICKDNADL--LSPLKKWKSRYLMEQN 843
            +EE  T   S P  T T H   S+    +S  S+I   + D    +P     +     ++
Sbjct: 645  VEESTTYHRS-PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 703

Query: 844  VTKLLRPLSPVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNT 903
             T  + P S      P S +      TPG S    E     YS   SP T+L+ AS  + 
Sbjct: 704  TTSRISPGSTEITTLPGSTT------TPGLS----EASTTFYSSPRSPTTTLSPASMTSL 753

Query: 904  PLQFELCHRKDLD---LAKVGYLDSNTNSCADRPSLLNS---GHSDLAPHPSLGPTSETG 957
             +  E    +       + V    + T   ++  + + S   G ++    P    TS  G
Sbjct: 754  GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHG 813

Query: 958  -----FPSRSGDGHQTL-VRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKP 1011
                 F SR    H TL   +S  +  TE +  +  SP +           + L  +   
Sbjct: 814  EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 873

Query: 1012 LHLDGGYC----SPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVS 1067
                 G      SPA   +S    GL+ + +   LSP        +P +P  P   +K +
Sbjct: 874  FPSSSGSTGTKLSPARSTTS----GLVGESTPSRLSPSSTETTT-LPGSPTTPSLSEKST 928

Query: 1068 LLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGS--------SNSVSD-----TGAHG 1114
                  R  +A  + A         +S ++ +  GS        S + SD     T +H 
Sbjct: 929  TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 988

Query: 1115 VQGSSARTPSSPHKKFSPSHSSMSHLEAVSPS--DSRGTSSSHCRPQENISSRWMVPTSV 1172
             QGS+  T        SP  ++ S L   S +   S G + +   P + I+S  +V  S 
Sbjct: 989  SQGSTEAT-------LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEAST 1040

Query: 1173 ERLREGGSIPKVLR----SSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSAL--- 1225
                  GS+   L     +S  + ++     +W S+     S P     P  +S+     
Sbjct: 1041 PTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSR 1100

Query: 1226 --SKGATVYSPS-----RYSYQLLQCDSPRTESQSLL--QQSSSPFRGHPTQSP--GYSY 1274
              S   T +S S     R         SP     +L   + ++S   G PT SP    S 
Sbjct: 1101 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 1160

Query: 1275 RTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSN 1334
             TTAL PG+  + G SE S  +T YSSP  P +T                          
Sbjct: 1161 ETTAL-PGSTTTAGLSEKS--TTFYSSPRSPDTT-------------------------- 1191

Query: 1335 LPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSA 1394
                    S AS T  G S+  T+   S S  G+  +T+FP ++     S   T S  S 
Sbjct: 1192 -------LSPASTTSSGVSEESTT---SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1241

Query: 1395 GQS 1397
            G +
Sbjct: 1242 GST 1244



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 211/952 (22%), Positives = 322/952 (33%), Gaps = 144/952 (15%)

Query: 535  PLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAG 594
            P   ++S V   +TTS +  G    T  P+S            +TP     +T   S  G
Sbjct: 469  PASTTSSGVSEESTTSRSRPGSTHTTAFPDST-----------TTPGLSRHSTTSHSSPG 517

Query: 595  DIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSN 654
                  L      + PS+    S  S   T +A         +  Q E +      G ++
Sbjct: 518  STDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQ-ESTTFHSNPGSTH 576

Query: 655  SLVTP---TEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDK 711
            + + P   T +G +++S      TGS  T +S         AS      +   T +    
Sbjct: 577  TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS--------PASSTSPGLQGESTAFQTHP 628

Query: 712  AEKQECPVECPLRITTDPTVLATTLNMLPG---LIHSPLICTTPKHYIRFGSPFIPERRR 768
            A     P   P    T P   +TT +  PG     H P   TT  H  +  + F      
Sbjct: 629  ASTHTTP--SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK-STIFHSSPDA 685

Query: 769  RPLLPDGTFSSCKKRW--IKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNAD 826
                P    S+   R       +  G T+ +++P  T T  L +++    SS   +    
Sbjct: 686  SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP--RSPTT 743

Query: 827  LLSPLKKWKSRYLMEQNVTKLLRP---LSPVTPPPPNSGSKSPQLATPGSSHPGEEECRN 883
             LSP     S  + E++ T   +P    S V+P    +   S +  T  SS  G  E   
Sbjct: 744  TLSPASM-TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTE--- 799

Query: 884  GYSLMFSPVTSLTTASRCNTPLQFELCHRKDLDLAKVGYLDSNTNSCADR--------PS 935
              + +F   T  TT+     P  F   H +        + + +T S            P+
Sbjct: 800  --TTVFPHST--TTSVHGEEPTTF---HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852

Query: 936  LLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPR 995
               +G         LG  S T FPS SG     L      A  T   L+   +P    P 
Sbjct: 853  STQTGLPATLTTADLGEESTT-FPSSSGSTGTKL----SPARSTTSGLVGESTPSRLSPS 907

Query: 996  ADGLYR--GSPLVGD---------RKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSP 1044
            +       GSP               P   D    SPA   SS    G+ ++ S     P
Sbjct: 908  STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL-SPATTTSS----GVSEESSTSHSQP 962

Query: 1045 GGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSS 1104
            G        P +       ++ +     +   EA  +       S   +S +  +  G +
Sbjct: 963  GSTHTT-AFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1021

Query: 1105 NSV---SDTGAHGVQGSSARTPSSP---HKKFSPSHSSMSHLEAVS------PSDSRGTS 1152
             +     DT   G+  +S  T SS    H   +P+ S+ + L+  S      PS S  T 
Sbjct: 1022 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1081

Query: 1153 SS--------------HCRPQENISSRWMVP-TSVERLREGGSI------------PKVL 1185
            S               H RP    ++ +    T++ R  E  ++            P   
Sbjct: 1082 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRS 1141

Query: 1186 RSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCD 1245
             +SV V   GEP+    S I+   ++     G  T +    K  T YS  R     L   
Sbjct: 1142 ATSVLV---GEPTT---SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTL--- 1192

Query: 1246 SPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHP 1305
            SP + + S + + S+     P  +   ++  +   PG      +S SS  ST  +     
Sbjct: 1193 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 1252

Query: 1306 VSTDSLAP----FTGTPGYFSSQPHSGNSTGSNLPRRSCP--SSAASPTLQGPSDSPTSD 1359
             +  SL P    F  +PG   +     N+T S L   S P  SS  SP         T+ 
Sbjct: 1253 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP--------HTTL 1304

Query: 1360 SVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
            S + S+T    ST+F      S PS   T+  P    SA  + S  S  S S
Sbjct: 1305 SPAGSTTRQGESTTF-----QSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1351



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 96/394 (24%), Positives = 145/394 (36%), Gaps = 97/394 (24%)

Query: 1075 KQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSV--------------SDTGAHGVQGSSA 1120
            ++    +S+ G  D+A S   +     G  ++                 T + G+  +S 
Sbjct: 535  QESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST 594

Query: 1121 RTPSS---PHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLRE 1177
            R  SS   P    SP+ S+   L+  S +     +S+H  P    ++   V  S    R 
Sbjct: 595  RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 654

Query: 1178 GGSIPKV-LRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSR 1236
             GS P     +S   +   E S  + S      S  A G  P +  S  S G    + SR
Sbjct: 655  PGSTPTTHFPASSTTSGHSEKSTIFHS------SPDASGTTPSSAHSTTS-GRGESTTSR 707

Query: 1237 YSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSS 1296
                                            SPG +  TT   PG+  + G SE+  S+
Sbjct: 708  I-------------------------------SPGSTEITTL--PGSTTTPGLSEA--ST 732

Query: 1297 TSYSSPAHPVSTDSLAPFT----GTPGYFS-SQPHSGNSTGSNLPRRSCPSSAASPTLQG 1351
            T YSSP  P +T S A  T    G     S SQP S +ST S       P+S  +P L  
Sbjct: 733  TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-------PASTTTPGL-- 783

Query: 1352 PSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTI--SLPSAGQSAVYQASRVSA-- 1407
               S  S +V  SS G+  +T FP ++ +S+  +  T   S P++  + ++     ++  
Sbjct: 784  ---SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGL 840

Query: 1408 VSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQTGL 1441
               S  +P                GS   TQTGL
Sbjct: 841  TEESTAFP----------------GSPASTQTGL 858



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 73/320 (22%), Positives = 126/320 (39%), Gaps = 47/320 (14%)

Query: 1102 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN 1161
            GS+ + +  G+    G S ++ +      SP  +++S     S   S  +++SH RP   
Sbjct: 1158 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPD-TTLSPASTTSSGVSEESTTSHSRPGST 1216

Query: 1162 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL 1221
             ++ +   T++         P V + S         SP          S  A   GPE+ 
Sbjct: 1217 HTTAFPGSTTM---------PGVSQESTA----SHSSPGSTDTTLSPGSTTASSLGPEST 1263

Query: 1222 SSALSKGAT---VYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTA 1278
            +   S G+T   +   +  +  LL+  +P   S      + SP      Q    ++++  
Sbjct: 1264 TFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWP 1323

Query: 1279 LRPGN---PPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNL 1335
                    PP+  S+   LS+TS+ SP+           T T  + +S    G S  S  
Sbjct: 1324 SSKDTMPAPPTTTSAFVELSTTSHGSPSS----------TPTTHFSASSTTLGRSEESTT 1373

Query: 1336 PRRSCPSSAASPTLQGPSDSPTSDSVSQS-----STGTLSSTSFPQN---------SRSS 1381
               S  ++A +P+   P+ S TS  V +S     S G+  +  FP++         SR+S
Sbjct: 1374 VHSSPVATATTPS---PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS 1430

Query: 1382 LPSDLRTISLPSAGQSAVYQ 1401
              S   TIS P +  SA+ +
Sbjct: 1431 HSSTTHTISSPPSTTSALVE 1450


>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 89/345 (25%), Positives = 129/345 (37%), Gaps = 21/345 (6%)

Query: 1073 KRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAH--GVQGSSARTPSSPHKKF 1130
            +RK   K++ A     S QS   S+     SS + S       G   +S    SS     
Sbjct: 3    ERKAACKQHRASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISST 62

Query: 1131 SPSHSSMSHLEAVSPSDSRGTSSSHCRPQ--ENISSRWMVPTSVERLREGGSIPKVLRSS 1188
                SS +   + S   S  +S+  C+     + S  W    +    R   S       S
Sbjct: 63   CSCQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCS 122

Query: 1189 VRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPR 1248
             + ++    S + +S+ T   S     +   T S++ S     Y  SR S     C S  
Sbjct: 123  CQSSRTSSTSCSCQSSRT---SSTCSCQTSRTSSTSCS-----YQSSRTS-STCSCQSSG 173

Query: 1249 TESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESS-LSSTSYSSPAHPVS 1307
            T S S   QSS        QS G S  + + +     S  S +SS  SSTS S  +   S
Sbjct: 174  TSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTS 233

Query: 1308 TDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTG 1367
            +      +GT     S   S  S+       SC SS  S T      S TS + S  S+G
Sbjct: 234  STCSCQSSGTSSTSCSWQSSRTSSTC-----SCQSSRTSSTSCSCQSSGTSSTCSCQSSG 288

Query: 1368 TLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ 1412
            T S++   Q+SR+S     +     S   S   Q+SR S+  + Q
Sbjct: 289  TSSTSCSCQSSRTSSTCSCQFSRTSSTSCSC--QSSRTSSTCSCQ 331



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 87/333 (26%), Positives = 128/333 (38%), Gaps = 21/333 (6%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSH-LEAVSPSD 1147
            S QS   S+ +    S+ +S T +    G+S+ + S    + S + S  S    + S S 
Sbjct: 41   SCQSSGTSSTSCNWQSSRISSTCSCQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSW 100

Query: 1148 SRGTSSSHCRPQENISSRWMVPTSVERLREGG-SIPKVLRSSVRVAQKGEPSPTWESNIT 1206
                +SS CR Q + +S         R      S      SS    Q    S T  S  +
Sbjct: 101  QFSRTSSTCRCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQS 160

Query: 1207 EKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHP 1266
             + S     +   T S++ +     +  SR S     C S  T S S   QSS       
Sbjct: 161  SRTSSTCSCQSSGTSSTSCN-----WQSSRTS-STCSCQSSGTSSTSYSCQSSGTSSTCS 214

Query: 1267 TQSPGYSYRTTALRPGNPPSHGSSESS-LSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQP 1325
             QS G S  + + +     S  S +SS  SSTS S  +   S+      + T     S  
Sbjct: 215  CQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTSCSCQ 274

Query: 1326 HSGNST-------GSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNS 1378
             SG S+       G++    SC SS  S T        +S S S  S+ T SST   Q+S
Sbjct: 275  SSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRT-SSTCSCQSS 333

Query: 1379 RSSLPSDLRTISLPSAGQSAVYQASRVSAVSNS 1411
             +S  S +      S+G S+   + R S  S++
Sbjct: 334  GTSSTSCI----CWSSGTSSTSCSGRFSGTSST 362


>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 93/347 (26%), Positives = 130/347 (37%), Gaps = 25/347 (7%)

Query: 1073 KRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSP 1132
            +RK   K++ A     S QS   S+     SS + S         SS  + +S + + S 
Sbjct: 3    ERKAACKQHRASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQ----SSGTSSTSCNWQSSR 58

Query: 1133 SHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVA 1192
            + S+ S         S GTSS+ C  Q + +S      S        S      SS    
Sbjct: 59   TSSTCS-------CQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCC 111

Query: 1193 QKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQ------LLQCDS 1246
            Q    S T  S  + + S  +        SS  S   +  S +  SYQ         C S
Sbjct: 112  QSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQS 171

Query: 1247 PRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESS-LSSTSYSSPAHP 1305
              T S S   QSS        QS G S  + + +     S  S +SS  SSTS S  +  
Sbjct: 172  SGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSG 231

Query: 1306 VSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSS 1365
             S+      +GT     S   S  S+       SC SS  S T      S TS + S  S
Sbjct: 232  TSSTCSCQSSGTSSTSCSWQSSRTSSTC-----SCQSSGTSSTSCSCQSSGTSSTCSCQS 286

Query: 1366 TGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ 1412
            +GT S++   Q+SR+S     +     S   S   Q+SR S+  + Q
Sbjct: 287  SGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSC--QSSRTSSTCSCQ 331



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 78/299 (26%), Positives = 108/299 (36%), Gaps = 25/299 (8%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS---HSSMSHLEAVSP 1145
            S QS   S+ +    S+  S T +    G+S+ + S    + S +    SS +   + S 
Sbjct: 64   SCQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSC 123

Query: 1146 SDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPT---WE 1202
              SR TSS+ C  Q + +S      +        S      SS    Q    S T   W+
Sbjct: 124  QSSR-TSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQ 182

Query: 1203 SNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPF 1262
            S+ T             T  S  S G +             C S  T S S   QSS   
Sbjct: 183  SSRTSSTCSCQSSGTSSTSYSCQSSGTS---------STCSCQSSGTSSTSCSCQSSGTS 233

Query: 1263 RGHPTQSPGYSYRTTALRPGNPPSHGSSESS-LSSTSYSSPAHPVSTDSLAPFTGTPGYF 1321
                 QS G S  + + +     S  S +SS  SSTS S  +   S+      +GT    
Sbjct: 234  STCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTS 293

Query: 1322 SSQPHSGNSTG-------SNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTS 1373
             S   S  S+        ++    SC SS  S T    S   +S S    S+GT SSTS
Sbjct: 294  CSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGTSSTSCICWSSGT-SSTS 351


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 85/314 (27%), Positives = 123/314 (39%), Gaps = 29/314 (9%)

Query: 1124 SSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPK 1183
            S+P   FS S +++ H E  +P  S   +++   P    ++   V  S    R  GS   
Sbjct: 375  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQT 434

Query: 1184 V-LRSSVRVAQKGEPSPTWESNITE-KDSDPADGEGPETLSSALSKGATVYSPSRYSYQL 1241
            +    S   +   E S T+  + T  K S P+        S   S G+T  +  R S  +
Sbjct: 435  MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 494

Query: 1242 --------LQCDSPRTESQSLLQQSSSP--FRGHPTQSP--GYSYRTTALRPGNPPSHGS 1289
                        SP   + ++L   S+P    G  T SP    S  TTAL PG+    G 
Sbjct: 495  SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGL 553

Query: 1290 SESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASP-- 1347
            SE   S+T YSSP  P +T    P + T    S +  + +S   +    + P S   P  
Sbjct: 554  SEK--STTFYSSPRSPDTTH--LPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL 609

Query: 1348 ----TLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLP-SAGQSAVYQA 1402
                T    S  PT  ++S  ST T SS      +  S P    T  LP +   S + +A
Sbjct: 610  SQESTASHSSPGPTDTTLSPGST-TASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 668

Query: 1403 SRVSAVSNSQHYPH 1416
            S    V +S   PH
Sbjct: 669  S--MPVHSSTRSPH 680



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 143/678 (21%), Positives = 237/678 (34%), Gaps = 126/678 (18%)

Query: 797  SSVPQETRT--QHLYQSNENSSSSSICKDNADLLSPLKKWKSRYLMEQNVTKLLRPLSPV 854
            SS P  T       Y S+  S+ ++  +D++ +    ++ K+ +     +   + P    
Sbjct: 462  SSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGST 521

Query: 855  --------TPPPPNSGSKSPQLATPGSSHPG-EEECRNGYSLMFSPVTSLTTASRCNTPL 905
                    TP P +SGS         ++ PG  E+    YS   SP T+   AS  ++ +
Sbjct: 522  PSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGV 581

Query: 906  QFE--LCHRKDLDLAKVGYLDSNTNSCADRPSLLNS---GHSDLAPHP------SLGPTS 954
              E    H +        +  S T     + S  +    G +D    P      SLGP  
Sbjct: 582  SEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEY 641

Query: 955  ETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRA----------------DG 998
             T F SR G    TL+ ++     T   L+ A  P+++  R+                  
Sbjct: 642  TT-FHSRPGSTETTLLPDNT----TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 696

Query: 999  LYRGSPLVGDRKPLH--LDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERA--CEGVP 1054
             +   P   D +P        +  P     S   HG    +    +S     +   E   
Sbjct: 697  TFHSWPSSNDTRPAPPTTTSAFVEP-----STTSHGSPSSIPTTHISARSTTSGLVEEST 751

Query: 1055 SAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVS-----D 1109
            +   +P   + +   E         + ++G G +S  S S +      + ++ S      
Sbjct: 752  TYHSSPGSTQTMHFPE--------SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 803

Query: 1110 TGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVP 1169
            T  H   GS+A T    H   S + S  S  E+++   S+  + +   P  + +S  +  
Sbjct: 804  TSYHSSPGSTATT----HFPDSSTTSGRSE-ESIASHSSQDATGTIVLPARSTNSVLLGE 858

Query: 1170 TSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESN------ITEKDSDPADGEGPETLSS 1223
            ++   +  G      L  S       E S T+ S+           S  + G   E+ +S
Sbjct: 859  STTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 918

Query: 1224 ALSKGAT--------VYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFR-GHPTQSP--GY 1272
                G+T          +P    +      SP +   +LL  S++    G PT SP    
Sbjct: 919  HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSG 978

Query: 1273 SYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTG 1332
            S  TTAL PG+  + G SE S  +T YSSP  P +T                        
Sbjct: 979  STETTAL-PGSTTTAGLSEKS--TTFYSSPRSPDTT------------------------ 1011

Query: 1333 SNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLP 1392
                      S AS T  G S+  T+   S S  G+  +T+FP ++     S   T S  
Sbjct: 1012 ---------LSPASTTSSGVSEESTT---SHSRPGSTHTTAFPGSTTMPGVSQESTASHS 1059

Query: 1393 SAGQSAVYQASRVSAVSN 1410
            S G +    + R +  S+
Sbjct: 1060 SPGSTDTTLSPRSTTASS 1077



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 79/323 (24%), Positives = 134/323 (41%), Gaps = 53/323 (16%)

Query: 1102 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN 1161
            GS+ + +  G+    G S ++ +      SP  +++S     S   S  +++SH RP   
Sbjct: 978  GSTETTALPGSTTTAGLSEKSTTFYSSPRSPD-TTLSPASTTSSGVSEESTTSHSRPGST 1036

Query: 1162 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL 1221
             ++ +   T++         P V + S   A    P  T ++ ++ + S  A   GPE+ 
Sbjct: 1037 HTTAFPGSTTM---------PGVSQEST--ASHSSPGST-DTTLSPR-STTASSLGPEST 1083

Query: 1222 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP 1281
            +     G+T  +        L  D+  T +  LL+ S+      P  S   S RTT    
Sbjct: 1084 TFHSGPGSTETT--------LLPDN--TTASGLLEAST------PVHSSTGSPRTTLSPA 1127

Query: 1282 GNPPSHGSSES--SLSSTSYSSPAHPVSTDSLAPFT----GTPGYFSSQPHSGNST--GS 1333
            G+    G S +  S  S+  + PA P +T +    +    G+P    +   S +ST  G 
Sbjct: 1128 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGR 1187

Query: 1334 NLPRRSCPSSAASP-TLQGPSDSPTSDSVSQS-----STGTLSSTSFPQN---------S 1378
            +    +  SS  +P T   P+ S TS  V +S     S G+  +  FP++         S
Sbjct: 1188 SEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES 1247

Query: 1379 RSSLPSDLRTISLPSAGQSAVYQ 1401
            R+S  S   TIS P +  SA+ +
Sbjct: 1248 RTSHSSTTHTISSPPSTTSALVE 1270



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 178/880 (20%), Positives = 292/880 (33%), Gaps = 138/880 (15%)

Query: 546  TTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKP 605
            +T T   P  + T     ES  S+S +  TI S P +                  LV +P
Sbjct: 759  STQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSA---------------LVEEP 803

Query: 606  PPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAALEEGGSNSLVTPTEAGSL 665
                 S     +      ++++ R +    +++ Q       L    +NS++      S 
Sbjct: 804  TSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSP 863

Query: 666  DSSG--ENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEWLNDKAEKQECPVECPL 723
             SSG  E   L GS  T      S    ++ + P T     +   +  +E+         
Sbjct: 864  ISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEE--------- 914

Query: 724  RITTDPTVLATTLNMLPGLIHS---PLICTTP---KHYIRFGSPFIPERRRRPLLPDGTF 777
                     +TT +  PG  H+   P   TTP   +H     S   P      LLP  T 
Sbjct: 915  ---------STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS--PGSTDTTLLPASTT 963

Query: 778  SSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADLLSPLKKWKSR 837
            +          +  G T+T+++P  T T  L + +    SS    D    LSP     S 
Sbjct: 964  TXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT--LSPASTTSSG 1021

Query: 838  YLMEQNVTKLLRPLSPVTPPPPNSGSKS--PQLATPGSSHPGEEECRNGYSLMFSPVTSL 895
             + E++ T   RP S  T   P S +     Q +T   S PG  +     S   +  +SL
Sbjct: 1022 -VSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD--TTLSPRSTTASSL 1078

Query: 896  TTASRC--NTPLQFELCHRKDLDLAKVGYLDSNT----NSCADRPSLLNSGHS------- 942
               S    + P   E     D   A  G L+++T    ++ + R +L  +G +       
Sbjct: 1079 GPESTTFHSGPGSTETTLLPDNTTAS-GLLEASTPVHSSTGSPRTTLSPAGSTTRQGEST 1137

Query: 943  ---------DLAPHPSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAM 993
                     D  P P   PT+ + F   S   H     +      T F+   A S     
Sbjct: 1138 TFQSWPSSKDTMPAP---PTTTSAFVELSTTSH----GSPSSIPTTHFS---ASSTTFGR 1187

Query: 994  PRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGV 1053
                     SP+     P        SPA   +S    GL+++ +    SPG  +     
Sbjct: 1188 SEESTTVHSSPVAPATTP--------SPARSTTS----GLVEESTAYHSSPGSTQTM--- 1232

Query: 1054 PSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAH 1113
                  P         E  +    +  ++      +  +  +   +   S  S++ T   
Sbjct: 1233 ----HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP 1288

Query: 1114 GVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVE 1173
                +S R+  S     SP  + ++ L A   +  R   S         ++ ++ P S+E
Sbjct: 1289 ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAES---------TTFYISPGSME 1339

Query: 1174 RLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYS 1233
                  +    L +   +      SP    +     S    GE     S A S   T + 
Sbjct: 1340 TTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAF- 1398

Query: 1234 PSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHP-----TQSPGYSYRTTALRPGNPPSHG 1288
                         P + + S L Q S+ F   P     T SPG S  T++        H 
Sbjct: 1399 -------------PASTTTSGLSQESTTFHSKPGSTETTLSPG-SITTSSFAQEFTTPHS 1444

Query: 1289 SSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP------- 1341
               S+LS+ S +S   P  ++    F  +PG   +   S ++T S   ++S P       
Sbjct: 1445 QPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGF 1504

Query: 1342 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSS 1381
            +    P     +D     +   SS+    +T  P  S +S
Sbjct: 1505 THTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTAS 1544



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/368 (22%), Positives = 130/368 (35%), Gaps = 47/368 (12%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            ++  G  + + +  +S G+ Q      S T +   + S+    S+ H K S   ++ +  
Sbjct: 413  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 472

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQK------ 1194
                 S    T ++H R    IS R       E  +   S P  + ++V  A        
Sbjct: 473  HTSYHSSLGSTETTHFRDSSTISGR------SEESKASHSSPDAMATTVLPAGSTPSVLV 526

Query: 1195 GEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSL 1254
            G+ +P   S I+    +     G  T      K  T YS  R S       +  T S   
Sbjct: 527  GDSTP---SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR-SPDTTHLPASMTSSGVS 582

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAP- 1313
             + ++S  R   T +  +   TT   PG      +S SS   T  +      +  SL P 
Sbjct: 583  EESTTSHSRPGSTHTTAFPGSTT--MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE 640

Query: 1314 ---FTGTPGYFSSQPHSGNSTGSNLPRRSCP------------SSAASPTLQGPSDS--- 1355
               F   PG   +     N+T S L   S P            S A S T QG S +   
Sbjct: 641  YTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHS 700

Query: 1356 -PTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAG-------QSAVYQASRVSA 1407
             P+S+    +   T S+   P  +    PS + T  + +         +S  Y +S  S 
Sbjct: 701  WPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGS- 759

Query: 1408 VSNSQHYP 1415
             + + H+P
Sbjct: 760  -TQTMHFP 766



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 25/146 (17%)

Query: 1258 SSSPFRGHPTQSP--GYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFT 1315
            ++S F G P  SP    S  TTAL PG+  + G SE S  +T YSSP  P  T S A  T
Sbjct: 165  ATSVFVGEPKTSPITSASMETTAL-PGSTTTAGLSEKS--TTFYSSPRSPDRTLSPARTT 221

Query: 1316 GT--------------PGYFSSQPHSGNSTG---SNLPRRSCPSSA---ASPTLQGPSDS 1355
             +              P +  + P S    G    +    S P S     SP    PS  
Sbjct: 222  SSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL 281

Query: 1356 PTSDSVSQSSTGTLSSTSFPQNSRSS 1381
                +   SS G   +T  P N+ +S
Sbjct: 282  GPESTTFHSSPGYTKTTRLPDNTTTS 307


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 85/314 (27%), Positives = 123/314 (39%), Gaps = 29/314 (9%)

Query: 1124 SSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPK 1183
            S+P   FS S +++ H E  +P  S   +++   P    ++   V  S    R  GS   
Sbjct: 310  STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQT 369

Query: 1184 V-LRSSVRVAQKGEPSPTWESNITE-KDSDPADGEGPETLSSALSKGATVYSPSRYSYQL 1241
            +    S   +   E S T+  + T  K S P+        S   S G+T  +  R S  +
Sbjct: 370  MHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 429

Query: 1242 --------LQCDSPRTESQSLLQQSSSP--FRGHPTQSP--GYSYRTTALRPGNPPSHGS 1289
                        SP   + ++L   S+P    G  T SP    S  TTAL PG+    G 
Sbjct: 430  SGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGL 488

Query: 1290 SESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASP-- 1347
            SE   S+T YSSP  P +T    P   T    S +  + +S   +    + P S   P  
Sbjct: 489  SEK--STTFYSSPRSPDTTH--LPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGL 544

Query: 1348 ----TLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLP-SAGQSAVYQA 1402
                T    S  PT  ++S  ST T SS      +  S P    T  LP +   S + +A
Sbjct: 545  SQESTASHSSPGPTDTTLSPGST-TASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEA 603

Query: 1403 SRVSAVSNSQHYPH 1416
            S  + V +S   PH
Sbjct: 604  S--TPVHSSTRSPH 615



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 93/396 (23%), Positives = 142/396 (35%), Gaps = 48/396 (12%)

Query: 1074 RKQEAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPS 1133
            R       S GG   SA + S S      S   VS T   G         S+  K F  S
Sbjct: 20   RSSSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITG---------STATKHFLDS 70

Query: 1134 HSSMSHLEAVSPSDSR-GTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVA 1192
             ++  H E  + S S  G + +   P  + +S ++       +         L  S   A
Sbjct: 71   STNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTA 130

Query: 1193 QKGE-----------------PSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPS 1235
               E                 P+ T  S ++EK +      GP T + A     T+   S
Sbjct: 131  GLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGP-THTIAFPDSTTMPGVS 189

Query: 1236 RYSYQLLQCD-------SPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHG 1288
            + S              SP T + S L   S+ F      SPGY+ +TT L P N  + G
Sbjct: 190  QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHS----SPGYT-KTTRL-PDNTTTSG 243

Query: 1289 SSESSLS-STSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASP 1347
              E+S    +S  SP   +S  S     G P  F S P S +++ +     S     ++ 
Sbjct: 244  LLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTT 303

Query: 1348 TLQGPSDSPTSDSVSQSSTGTLSSTSFPQNS----RSSLPSDLRTISLPSAGQSAVYQAS 1403
                PS +PT+   + S+T   S  S P +S     ++ P   R+ +     +S  Y  S
Sbjct: 304  YHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRS 363

Query: 1404 RVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQT 1439
              S  + + H+P   +   H        GS   T++
Sbjct: 364  PGS--TQTMHFPESSTTSGHSEESATFHGSTTHTKS 397



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 81/368 (22%), Positives = 130/368 (35%), Gaps = 47/368 (12%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHL 1140
            ++  G  + + +  +S G+ Q      S T +   + S+    S+ H K S   ++ +  
Sbjct: 348  SATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALA 407

Query: 1141 EAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQK------ 1194
                 S    T ++H R    IS R       E  +   S P  + ++V  A        
Sbjct: 408  HTSYHSSLGSTETTHFRDSSTISGR------SEESKASHSSPDAMATTVLPAGSTPSVLV 461

Query: 1195 GEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSL 1254
            G+ +P   S I+    +     G  T      K  T YS  R S       +  T S   
Sbjct: 462  GDSTP---SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPR-SPDTTHLPARMTSSGVS 517

Query: 1255 LQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAP- 1313
             + ++S  R   T +  +   TT   PG      +S SS   T  +      +  SL P 
Sbjct: 518  EESTTSHSRPGSTHTTAFPGSTT--MPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPE 575

Query: 1314 ---FTGTPGYFSSQPHSGNSTGSNLPRRSCP------------SSAASPTLQGPSDS--- 1355
               F  +PG   +     N+T S L   S P            S A S T QG S +   
Sbjct: 576  YTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHS 635

Query: 1356 -PTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAG-------QSAVYQASRVSA 1407
             P+S     +   T S+   P  +    PS + T  + +         +S  Y +S  S 
Sbjct: 636  WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGS- 694

Query: 1408 VSNSQHYP 1415
             + + H+P
Sbjct: 695  -TQTMHFP 701


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 4/126 (3%)

Query: 286  LRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGN 345
            L AA+DL   T++IEY G ++  +        +++    +  +   N  E  +DA   G 
Sbjct: 5411 LYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINN--EHVIDATLTGG 5468

Query: 346  DARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACH 405
             AR+I  SC PN     +  D    + I +   I K  E+T  + +++ +  +K+ C C 
Sbjct: 5469 PARYINHSCAPNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHC- 5527

Query: 406  KGNRNC 411
             G  NC
Sbjct: 5528 -GAWNC 5532



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 79/338 (23%), Positives = 117/338 (34%), Gaps = 67/338 (19%)

Query: 1121 RTPSSPHKKFSPSHSSM--SHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREG 1178
            R P    ++ S  H++   SH +  S S S  +S  H   Q ++S     P S+ +   G
Sbjct: 4096 RLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ-PGSMTQNLLG 4154

Query: 1179 GSIPKVLRSSVRVA--QKGEPSPTWESN--ITEKDSDPADGEGPETLSSALSKGATVYSP 1234
               P + R        Q  +P P  +S   +      P  G+    L   L+K   +   
Sbjct: 4155 PQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHL 4214

Query: 1235 SRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTAL--------------- 1279
            S    Q LQ        Q  LQQS +  +  P Q PG   +T+ L               
Sbjct: 4215 SPQQQQQLQA----LLMQRQLQQSQAVRQTPPYQEPGT--QTSPLQGLLGCQPQLGGFPG 4268

Query: 1280 -------------RPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPH 1326
                         RP  PP   +   +LS+     P HP    S       P    S P 
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS-PS 4327

Query: 1327 SGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSST-----------------GTL 1369
            S   T + LP    P+   +P  QGP+  P    VS ++                    L
Sbjct: 4328 SQLPTEAQLP----PTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383

Query: 1370 SSTSFPQNSRSSLPSDLRTIS---LPSAGQSAVYQASR 1404
            + T  P+ S S +P  L  ++   +P A Q ++ Q  R
Sbjct: 4384 AETQKPEQS-SLVPGHLDQVNGQVVPEASQLSIKQEPR 4420



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 4/95 (4%)

Query: 1281 PGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSC 1340
            PG+ P  G +  SL+S    SP   +  + LAP T    Y   +  +G   GS    +  
Sbjct: 1131 PGSQPEPGQTPGSLASELKGSPV-LLDPEELAPVTPMEVYPECKQTAGQ--GSPCEEQEE 1187

Query: 1341 PSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFP 1375
            P +  +PT      S   + +S  S G  +S SFP
Sbjct: 1188 PRAPVAPTPPTLIKSDIVNEISNLSQGD-ASASFP 1221


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)

Query: 276  VTRVQKHRKILRAARDLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVE 335
            V R   H + L   R++    ++IEY G +++R         F        +  + +  +
Sbjct: 2579 VYRSAIHGRGLFCKRNIDAGEMVIEYSG-IVIRSVLTDKREKFYDGKGIGCYMFRMDDFD 2637

Query: 336  MCVDARTFGNDARFIRRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSN 395
            + VDA   GN ARFI  SC PN   R +  +G  H+ I+A+  I +  E+T  + +   +
Sbjct: 2638 V-VDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIED 2696

Query: 396  CNYKVDCACHKGNRNC 411
             + K+ C C  G + C
Sbjct: 2697 ASNKLPCNC--GAKRC 2710



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 66/286 (23%), Positives = 97/286 (33%), Gaps = 43/286 (15%)

Query: 411 CPIQKRNPNATELPLLPPPP-------SLPTIGAETRRRKARRKELEMEQ--QNEASEEN 461
           CP      +   LP  PPPP       S P +   T  RK  R  L   Q  + EA+   
Sbjct: 429 CPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAG 488

Query: 462 NDQQSQEVPEKVTVSSDHEEVDNPEEKPEEEK-----EEVIDDQENLAHSRRTREDRKVE 516
            +  S   P   T +    E D+P   P+         + I    +   SR  +  R+  
Sbjct: 489 PEGTSPPTPTPSTATGGPPE-DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRR-- 545

Query: 517 AIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTI 576
                F + +  K     P +   S V     T+  PV +E       + V +     T 
Sbjct: 546 -----FMDEDPPK-----PPKVEVSPVLRPPITTSPPVPQEP------APVPSPPRAPTP 589

Query: 577 PSTPQSVGVNTR---RSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQ 633
           PSTP  +    R   R       +  + +P PPPA P  P P    +   +S    L R 
Sbjct: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRA 649

Query: 634 KQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDP 679
            Q    +A L           S++TP   G+ ++     P     P
Sbjct: 650 PQFTPSEAHLKI-------YESVLTPPPLGAPEAPEPEPPPADDSP 688


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 84/328 (25%), Positives = 122/328 (37%), Gaps = 45/328 (13%)

Query: 1118 SSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLRE 1177
            S  RTP        PS +S + + + +      +++S  R     S     P    R   
Sbjct: 174  SLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPP----RASP 229

Query: 1178 GGSIPKVLRS-----SVRVAQKGEPSPTW---ESNITEKDSDPADGEGPETLSSALSKGA 1229
             GS P+   S     ++ +      SPT     +++T+ DS  +    P   S+A   G 
Sbjct: 230  TGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTG- 288

Query: 1230 TVYSPSRYSYQLLQCDS------PRTESQSLLQQSS------------SPFRGHPTQSPG 1271
               +PSR S  +    +      PR     +L ++S            +P R   T++P 
Sbjct: 289  ---TPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPS 345

Query: 1272 YSYRT---TALRPGNPPSHGS---SESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFS--S 1323
             +  T   +   P   PS  S   S S+ S T  SS A P  T   A  TGTP   S   
Sbjct: 346  RASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTR 405

Query: 1324 QPHSGNSTGSNLPRRSCPS--SAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSS 1381
            +P   + TG  L R S     S ASPT   P  SPT      S TGT S  S      ++
Sbjct: 406  KPPRASPTGM-LSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTA 464

Query: 1382 LPSDLRTISLPSAGQSAVYQASRVSAVS 1409
             P+   + + P+   S        S  S
Sbjct: 465  SPTGSPSTASPTGSPSTASPTGSPSRAS 492



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 69/261 (26%), Positives = 98/261 (37%), Gaps = 28/261 (10%)

Query: 1116 QGSSARTPSSPHKKFSPSHSSMSHLEAV-SPSDSRGTSSSHCRPQENISSRWMVPTSVER 1174
            + S   TP       +PS +S +  ++  SP+ S  T+S    P     +      S+ R
Sbjct: 436  RASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTR 495

Query: 1175 LREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSP 1234
                 S+ K+  ++         SPTW    T   + P           + S+ A   +P
Sbjct: 496  TPSRASLTKMESTASITRTPSRASPTW----TPSTASPTGSPSTALAMGSPSRAALTRTP 551

Query: 1235 SRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSS--ES 1292
            SR S         RT S++ L   ++P R   T++P     +T L    PPS   +   S
Sbjct: 552  SRASLT-------RTPSRASL---TTPSRASLTRTP-----STVLLTRMPPSASPTGMPS 596

Query: 1293 SLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGP 1352
              S T   S A     DS A  T TP   S       ++ +  P R      ASPT   P
Sbjct: 597  RTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPR------ASPTGTPP 650

Query: 1353 SDSPTSDSVSQSSTGTLSSTS 1373
              SPT      S TGT S  S
Sbjct: 651  RASPTGTPPRASPTGTPSRAS 671



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 96/403 (23%), Positives = 148/403 (36%), Gaps = 61/403 (15%)

Query: 1033 LMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQS 1092
            + + LSR S +    RA      +P   P R  +S++            ++  G  S  S
Sbjct: 211  ITRTLSRASPTGTPPRA------SPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTS 264

Query: 1093 KSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS-MSHLEAVSPSDSRGT 1151
             +K       S+ S++ T +     S   TPS      +PS +S M  L   SP+     
Sbjct: 265  LTK-----MDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSR 319

Query: 1152 SSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSD 1211
            +S          ++     S+ R     SI    R+  R +  G+PS T     T   + 
Sbjct: 320  TSL---------TKMDSTASISRTPPRASIT---RTPSRASPTGKPS-TASPTGTPSRAS 366

Query: 1212 PADGEGPETLSSALSKGATVYSPSRYS------YQLLQCDSPRTESQSLLQQSS------ 1259
            P       +L+   S  +   +P R S         L    PR     +L ++S      
Sbjct: 367  PTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDS 426

Query: 1260 ------SPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSP------AHPVS 1307
                  +P R  PT +P  +  T      +P    S+ S   S S +SP      A P  
Sbjct: 427  TASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTG 486

Query: 1308 TDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPS---SAASPT--------LQGPSDSP 1356
            + S A  T TP   S       ++ +  P R+ P+   S ASPT        +  PS + 
Sbjct: 487  SPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAA 546

Query: 1357 TSDSVSQSS-TGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSA 1398
             + + S++S T T S  S    SR+SL     T+ L     SA
Sbjct: 547  LTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSA 589



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 72/304 (23%), Positives = 118/304 (38%), Gaps = 11/304 (3%)

Query: 1089 SAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDS 1148
            ++ +++ S  +  G+ +  S TG      S   TPS      +P  +S+    +++    
Sbjct: 11   ASPTRTPSTASLTGTPSRASLTGTPST-ASLMGTPSRASLTGTPPRASLKGTTSMASLMV 69

Query: 1149 RGTSSSHCRPQEN-ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITE 1207
              + +S  R Q + + +R     S++R+    S  + L  +  + +    S T   +   
Sbjct: 70   SPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRAS 129

Query: 1208 KDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPT 1267
              + P+      +LS   S  A +  PSR S       +  T + S    + +P R  PT
Sbjct: 130  LTTTPSRA----SLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPT 185

Query: 1268 QSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHS 1327
              P    RT+     +  S    +S+ S T   S A P  T   A  TG+P   S     
Sbjct: 186  GMPS---RTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMP 242

Query: 1328 GNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLR 1387
              +     P R+ P+   S T     DS  S + + S   T S T  P  SR+SL     
Sbjct: 243  STALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTP--SRASLSMTPS 300

Query: 1388 TISL 1391
            T SL
Sbjct: 301  TASL 304



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 82/379 (21%), Positives = 129/379 (34%), Gaps = 20/379 (5%)

Query: 536 LEQSNSDVEITTTTSE-----TPVGEETKTEAPESEVSNSVSNVTIPSTP---QSVGVNT 587
           L + +S   IT T S      TP         P + +S   S   +  TP      G+ +
Sbjct: 202 LTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLS 261

Query: 588 RRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAELSQAA 647
           R S    D  A        P+  S     SR S   T S   L R     +    LS+ +
Sbjct: 262 RTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTS 321

Query: 648 LEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVSITGSHVNRAASKYPKTKKYLVTEW 707
           L +  S + ++ T   +  +   +R      P+  S TG+    + +  P T        
Sbjct: 322 LTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTAS---LTG 378

Query: 708 LNDKAEKQECPVECPLRITTDPTVLATTLNMLPGLIHSPLICTTPKHYIRFGSPFIPERR 767
           L+  A     P   P R +   T    +L   P    SP    +     +  S   P R 
Sbjct: 379 LSSTAS----PTGTPPRASPTGTPSTASLTRKPPRA-SPTGMLSRTSITKMDSTASPTRT 433

Query: 768 RRPLLPDGTFSSCKKRWIKQALEEGMTQTSSVPQETRTQHLYQSNENSSSSSICKDNADL 827
                P GT                 TQ+++ P  + +      + +++S +     A L
Sbjct: 434 PPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASL 493

Query: 828 L-SPLKKWKSRYLMEQNVTKLLRPLSPVTPPPPNS--GSKSPQLATPGSSHPGEEECRNG 884
             +P +   ++     ++T+     SP   P   S  GS S  LA    S        + 
Sbjct: 494 TRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSR 553

Query: 885 YSLMFSPV-TSLTTASRCN 902
            SL  +P   SLTT SR +
Sbjct: 554 ASLTRTPSRASLTTPSRAS 572


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 93/375 (24%), Positives = 139/375 (37%), Gaps = 48/375 (12%)

Query: 1091 QSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRG 1150
            Q +++SA  G   +  +   G  G  G   +  +  + + SP      H +   P  S+ 
Sbjct: 435  QGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQ 488

Query: 1151 TSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGE-PSPTWESNITEKD 1209
              S     Q +   +   P S     +    P   + S    Q+   P P+ +S   +  
Sbjct: 489  PPSQTPHAQPSYQQQ---PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545

Query: 1210 SDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQS 1269
                    P+  S    +     +PS  S Q      P+ +SQ   Q + S  R  P Q 
Sbjct: 546  QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY---PQPQSQQSQQTAYSQQRFPPPQE 602

Query: 1270 PGYSYRTTALRPGNPPSHGSSE--------------SSLSSTSYSSPAHPVSTD-SLAPF 1314
               S  +   +  + PS  SS+              SSL   S S    P+ T+ +L+P 
Sbjct: 603  --LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660

Query: 1315 TGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSD--SVSQSSTGTLSST 1372
              T G  SSQ    N   S     + P     P ++GPS SP     SV+QS +G LS  
Sbjct: 661  VSTSGISSSQGEQSNPAQSPFSPHTSPHL---PGIRGPSPSPVGSPASVAQSRSGPLSPA 717

Query: 1373 SFPQNSRSSLPSDLRTISL--PSAGQSAVYQASRVSAVSNSQ----HYPHRGSGGVHQYR 1426
            + P N     P   ++ S+  PS  QS++ Q  R     N Q      P  GS       
Sbjct: 718  AVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ-DRGYMQRNPQMPQYSSPQPGSA------ 770

Query: 1427 LQPLQGSGVKTQTGL 1441
            L P Q SG +  TG+
Sbjct: 771  LSPRQPSGGQIHTGM 785



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 470  PEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTR--EDRKVEAIMHAFENLEK 527
            P  +    + EE+  P+ + EEE+EEV+++ E +A S + +   +   E ++  F+ L  
Sbjct: 1756 PAPMEGGEEEEELLGPKLE-EEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPV 1814

Query: 528  RKKRRDQPLEQSNSD 542
            +  +++ P     SD
Sbjct: 1815 KIVQKNDPFVVDCSD 1829


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 93/375 (24%), Positives = 139/375 (37%), Gaps = 48/375 (12%)

Query: 1091 QSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRG 1150
            Q +++SA  G   +  +   G  G  G   +  +  + + SP      H +   P  S+ 
Sbjct: 435  QGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSP------HPQQQQPPYSQQ 488

Query: 1151 TSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGE-PSPTWESNITEKD 1209
              S     Q +   +   P S     +    P   + S    Q+   P P+ +S   +  
Sbjct: 489  PPSQTPHAQPSYQQQ---PQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHP 545

Query: 1210 SDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQS 1269
                    P+  S    +     +PS  S Q      P+ +SQ   Q + S  R  P Q 
Sbjct: 546  QSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAY---PQPQSQQSQQTAYSQQRFPPPQE 602

Query: 1270 PGYSYRTTALRPGNPPSHGSSE--------------SSLSSTSYSSPAHPVSTD-SLAPF 1314
               S  +   +  + PS  SS+              SSL   S S    P+ T+ +L+P 
Sbjct: 603  --LSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPG 660

Query: 1315 TGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSD--SVSQSSTGTLSST 1372
              T G  SSQ    N   S     + P     P ++GPS SP     SV+QS +G LS  
Sbjct: 661  VSTSGISSSQGEQSNPAQSPFSPHTSPHL---PGIRGPSPSPVGSPASVAQSRSGPLSPA 717

Query: 1373 SFPQNSRSSLPSDLRTISL--PSAGQSAVYQASRVSAVSNSQ----HYPHRGSGGVHQYR 1426
            + P N     P   ++ S+  PS  QS++ Q  R     N Q      P  GS       
Sbjct: 718  AVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQ-DRGYMQRNPQMPQYSSPQPGSA------ 770

Query: 1427 LQPLQGSGVKTQTGL 1441
            L P Q SG +  TG+
Sbjct: 771  LSPRQPSGGQIHTGM 785



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 470  PEKVTVSSDHEEVDNPEEKPEEEKEEVIDDQENLAHSRRTR--EDRKVEAIMHAFENLEK 527
            P  +    + EE+  P+ + EEE+EEV+++ E +A S + +   +   E ++  F+ L  
Sbjct: 1539 PAPMEGGEEEEELLGPKLE-EEEEEEVVENDEEIAFSGKDKPASENSEEKLISKFDKLPV 1597

Query: 528  RKKRRDQPLEQSNSD 542
            +  +++ P     SD
Sbjct: 1598 KIVQKNDPFVVDCSD 1612


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 112/452 (24%), Positives = 158/452 (34%), Gaps = 63/452 (13%)

Query: 948  PSLGPTSETGFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVG 1007
            P  GPT   G  SR+           ++A   +     +  P+++  RA G  R  PL  
Sbjct: 75   PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPL-- 129

Query: 1008 DRKPLHLDG------GYCSPAEGFSSRYEHGLMKDLSR---GSLSPGGERACEGV----- 1053
             +K L +        G  + A   S+    G  +D S    G+ SP   R          
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSA-LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 1054 -----PSAPQNPPQ---RKKVSLLEYRKRKQEA----KENSAGGGGDSAQSKSKSAGAGQ 1101
                 PSA   PP    RK VS        + +    +  SAGGG     S+S S+ A  
Sbjct: 189  LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 1102 GSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQEN 1161
             SS + S   A G       TP +P     P    +  L     +  R  ++    P  +
Sbjct: 249  LSSPARSGPSARG-------TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 1162 ISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETL 1221
                   P++  + +   ++P    SS    Q   P P            P     P +L
Sbjct: 302  SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL----------APPSPSAPPSL 351

Query: 1222 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP 1281
             +  S  AT   PS+ +  L       T S  L     SP    P Q+P       AL P
Sbjct: 352  QTLPSPPAT--PPSQATTSLGSPTLQATHS-FLPSPPLSPLATPPPQAPP----ALALPP 404

Query: 1282 GNPPSHGSSESSLSSTSYSSPAHP--VSTDSL-APFTGTPG----YFSSQPHSGNSTGSN 1334
               P    +   LS  +  SP  P  ++   L APF+  P        S P S   + S 
Sbjct: 405  LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 464

Query: 1335 LPRRSCPSSAASPTLQGPSDSPTSDSVSQSST 1366
             P    P S A+P LQ P   P S  +S S+T
Sbjct: 465  TPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 45/167 (26%), Positives = 69/167 (41%), Gaps = 19/167 (11%)

Query: 1263 RGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPG--- 1319
            R  PT+S G S R  A RP   P+ G  E +  + + +SP  PVS+   A  T  PG   
Sbjct: 76   RAGPTRSAGTSSRNPASRP---PASGRGERAPPAKN-TSPG-PVSSPGRASGTTRPGPLG 130

Query: 1320 ----YFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFP 1375
                  S++        +  P+RS  S+ A     GP+    S ++++ S    +    P
Sbjct: 131  QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190

Query: 1376 QNSRSSLPSDLRTISLPSAG-QSAVYQASRVSAVSNSQHYPHRGSGG 1421
            + + S+ P        P+ G + +V  AS  S    S     R S G
Sbjct: 191  RPAPSARPRP------PTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 78/352 (22%), Positives = 119/352 (33%), Gaps = 45/352 (12%)

Query: 1054 PSAPQNPPQRKKVSLLEYRKR----KQEAKENSAGGGGDSAQSKSKSAG----AGQGSSN 1105
            P +P+ PP     +L          ++   E + G GG +    +  AG    AG  S N
Sbjct: 30   PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89

Query: 1106 SVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSR 1165
              S   A    G   R P  P K  SP            P  S G +S   RP   +  +
Sbjct: 90   PASRPPA---SGRGERAP--PAKNTSPG-----------PVSSPGRASGTTRPGP-LGQK 132

Query: 1166 WMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSAL 1225
             +  ++ E +  G +     RS++    + + S                G  P T S A+
Sbjct: 133  GLRISAEETVARGKATEAPKRSALSAGARRDTS----------------GPTPGTPSPAM 176

Query: 1226 SKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPP 1285
            ++ +          +      PR  ++   +  SS    H T  P  + R      G   
Sbjct: 177  ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQ 235

Query: 1286 SHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAA 1345
               S   S S+T  SSPA   S  S       P +  SQP          P+ + P   A
Sbjct: 236  RPASRSLSSSATPLSSPAR--SGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDA 292

Query: 1346 SPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQS 1397
            +P L   S SP +     ++  + +  + P    SS  +      LP A  S
Sbjct: 293  APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS 344



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 11/149 (7%)

Query: 532 RDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSS 591
           R  PL Q    +    T +     E  K  A  +      S  T P TP       RRS 
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-PGTPSPA--MARRSR 181

Query: 592 QAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSA-QRLKRQKQANAQQAELSQAALEE 650
            AG    E  +P+P P+  +RPRP +   R   SSA +    +    A++   +   L+ 
Sbjct: 182 AAG---TEVGLPRPAPS--ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236

Query: 651 GGSNSLVTPTEAGSLDSSGENRPLTGSDP 679
             S SL   + A  L S   + P     P
Sbjct: 237 PASRSL--SSSATPLSSPARSGPSARGTP 263


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 95/364 (26%), Positives = 134/364 (36%), Gaps = 58/364 (15%)

Query: 1087 GDSAQSKS-KSAGAGQGSSNS-VSDTGAHGVQGSSARTPSSPHK-KFSPSHSSMSHLEAV 1143
            GD  + K+ K    G G+SNS +S  G     G  +RTPS+  K K  P     +  E  
Sbjct: 961  GDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGK 1020

Query: 1144 SPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWES 1203
            SPS S     S  RP       +  PTS    +  GS     RS         P P    
Sbjct: 1021 SPSHS-----SSNRP-------FTPPTSTGGSKSPGSAG---RSQTPPGVATPPIPK--- 1062

Query: 1204 NITEKDSDPADGEGPETLSSALSKGAT-VYSPSRYSYQLLQCDSPRTESQSLLQQSSSPF 1262
                             ++  + KG   V  PS +S          T S S+    S   
Sbjct: 1063 -----------------ITIQIPKGTVMVGKPSSHSQY--------TSSGSVSSSGSKSH 1097

Query: 1263 RGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDS--LAPFTGTPGY 1320
              H + S   S  +T+ +  +  S GSS S LSS+ YSS     S+ S   +   G PG 
Sbjct: 1098 HSHSSSSS--SSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGS 1155

Query: 1321 FSSQPH--SGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNS 1378
                 H  S  S+ + +  +  PSS  +P+L  P+ SP S S     +  L+S   P   
Sbjct: 1156 SPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISP-SHSRPPGGSDKLAS---PMKP 1211

Query: 1379 RSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQ 1438
                P   +  S  S+G    +  S  S+ S  +     GS G    +  P   S   + 
Sbjct: 1212 VPGTPPSSKAKSPISSGSGGSHM-SGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASS 1270

Query: 1439 TGLS 1442
            +  S
Sbjct: 1271 SSFS 1274



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 113/495 (22%), Positives = 177/495 (35%), Gaps = 78/495 (15%)

Query: 957  GFPSRSGDGHQTLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDG 1016
            G P   GD  +T  + ++QA   +F+++       A+  AD +   S   G + PL   G
Sbjct: 907  GVPMLGGDNGETKFKGNNQADTVDFSIISVAG--KALAPADLMEHHS---GSQGPLLTTG 961

Query: 1017 GYCSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQ 1076
                         + G  K   R     G   +    P     P +R +    + + + +
Sbjct: 962  -------------DLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDK 1008

Query: 1077 EAKENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSS 1136
              K   A       + KS S  +        + TG     GS+ R+ + P     P    
Sbjct: 1009 PPKRKKA-----DTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPP---- 1059

Query: 1137 MSHLEAVSPSDSRGTSSSHCRPQENISSRWMV--PTSVERLREGGSIPKVLRSSVRVAQK 1194
               +  ++    +GT               MV  P+S  +    GS+      S      
Sbjct: 1060 ---IPKITIQIPKGTV--------------MVGKPSSHSQYTSSGSVSS--SGSKSHHSH 1100

Query: 1195 GEPSPTWESNITEKDSDPADGEGPETLSSAL--SKGATVYSPSRYSYQLLQCDSPRTESQ 1252
               S +  S   +  S  ++G     LSS++  S+G++  S S+ S            SQ
Sbjct: 1101 SSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS------------SQ 1148

Query: 1253 SLLQQSSSPFRGHPTQSPGYSYRTTALRP-GNPPSHGSSESSLSSTSYSSPAHPVSTDSL 1311
            S  +  SSP   H   S   S   T ++P G P S  +   S  + S S    P  +D L
Sbjct: 1149 SGGKPGSSPITKHGLSSGSSS---TKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKL 1205

Query: 1312 A----PFTGT-PGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSST 1366
            A    P  GT P   +  P S  S GS++   S  S   S +  G S S +  +   S++
Sbjct: 1206 ASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNS 1265

Query: 1367 GTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQH-YPHRGSGGVHQY 1425
             T SS+SF  +  S   S  +  S      S   + S  + +   +H     G GG    
Sbjct: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGE--- 1322

Query: 1426 RLQPLQGS-GVKTQT 1439
               PL G  GV T +
Sbjct: 1323 --DPLDGQMGVSTNS 1335



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 114/511 (22%), Positives = 176/511 (34%), Gaps = 75/511 (14%)

Query: 853  PVTPPPPNSGSKSPQLATPGSSHPGEEECRNGYSLMFSPVTSLTTASRCNTPLQFELCHR 912
            P TPP    GSKSP  A    + PG         +   P+  +T      T +       
Sbjct: 1030 PFTPPTSTGGSKSPGSAGRSQTPPG---------VATPPIPKITIQIPKGTVM------- 1073

Query: 913  KDLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQTLVRN 972
                + K       T+S +   S   S HS  +   S   TS     S+S     + + +
Sbjct: 1074 ----VGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSS 1129

Query: 973  SDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGGYCSPAEGFSSRYEHG 1032
            S          MY+              +GS      K     GG      G S   +HG
Sbjct: 1130 S----------MYSS-------------QGSSGSSQSKNSSQSGG----KPGSSPITKHG 1162

Query: 1033 LMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGG----GGD 1088
            L    S   + P      +G PS+  NP    K ++     R     +  A       G 
Sbjct: 1163 LSSGSSSTKMKP------QGKPSSLMNP-SLSKPNISPSHSRPPGGSDKLASPMKPVPGT 1215

Query: 1089 SAQSKSKSA-GAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSD 1147
               SK+KS   +G G S+    + + G++ SS    S    + +P  SS S   + S   
Sbjct: 1216 PPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPP-SSNSCTASSSSFS 1274

Query: 1148 SRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNI-T 1206
            S G+S S  + Q   SS+   P+  ++      I K+    V     GE     +  + T
Sbjct: 1275 SSGSSMSSSQNQHG-SSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVST 1333

Query: 1207 EKDSDPADGEGPETLSSALSKGATVYSP---SRYSYQLLQCDSPRTESQSLLQQSSSPFR 1263
               S P   +    +S    +G    S    S+ S      DS +  S+S    S+   +
Sbjct: 1334 NSSSHPMSSK--HNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAK 1391

Query: 1264 ----GHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSP----AHPVSTDSLAPFT 1315
                 H   SP    + T  +PG     G      SS +Y SP    + P         +
Sbjct: 1392 IIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHS 1451

Query: 1316 GTPGYFSSQPHSGNSTGSNLPRRSCPSSAAS 1346
             +P Y      S + +GS++  +S  +S +S
Sbjct: 1452 KSPAYTPQNLDSESESGSSIAEKSYQNSPSS 1482



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 78/369 (21%), Positives = 122/369 (33%), Gaps = 44/369 (11%)

Query: 1038 SRGSLSPGGERA-----CEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQS 1092
            S GS+S  G ++          SA  +   +   S      +   +  +S G  G S   
Sbjct: 1085 SSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSK 1144

Query: 1093 KSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSHLEAVSPSDSR--G 1150
             S  +G   GSS        HG+   S+ T   P  K S   +       +SPS SR  G
Sbjct: 1145 NSSQSGGKPGSSPITK----HGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPG 1200

Query: 1151 TSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDS 1210
             S     P + +        +   +  G     +  +S     K         ++++K  
Sbjct: 1201 GSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQK-- 1258

Query: 1211 DPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSP-RTESQSLLQQSSSPFRGHPTQS 1269
             P         SS+ S   +  S S+  +   +  SP R +  SL         G  T  
Sbjct: 1259 TPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSG 1318

Query: 1270 PGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGN 1329
            PG          G  P  G    S +S+S     HP+S+             S     G 
Sbjct: 1319 PG----------GEDPLDGQMGVSTNSSS-----HPMSSKH---------NMSGGEFQGK 1354

Query: 1330 STGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTI 1389
               S+  +    +S +S      S   TS+S +  STG         +  S  PS    +
Sbjct: 1355 REKSDKDKSKVSTSGSSV----DSSKKTSESKNVGSTGVAKIIISKHDGGS--PSIKAKV 1408

Query: 1390 SLPSAGQSA 1398
            +L   G+S+
Sbjct: 1409 TLQKPGESS 1417



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 14/30 (46%), Positives = 18/30 (60%)

Query: 846  KLLRPLSPVTPPPPNSGSKSPQLATPGSSH 875
            KL  P+ PV   PP+S +KSP  +  G SH
Sbjct: 1204 KLASPMKPVPGTPPSSKAKSPISSGSGGSH 1233


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 83/303 (27%), Positives = 117/303 (38%), Gaps = 54/303 (17%)

Query: 1144 SPSDSRGTSSSHCRPQENISSRWMVPTSVE-----------RLREGGSIPKV-------L 1185
            SP  +  T +S   PQ+  +S    P S+             L   G  P V       L
Sbjct: 430  SPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSL 489

Query: 1186 RSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCD 1245
            +SS  V   GEP P++ S      S  A G GP T S           PS+ S       
Sbjct: 490  KSSATVT--GEP-PSYSSG--SDSSKAAPGPGPSTFSFV--------PPSKASLAPTPAA 536

Query: 1246 SPRTESQSLLQQSSSPFRG--HPTQSPGYSYRTTALRPGNPPSHGSSESSLSST-SYSSP 1302
            SP   S +     SS F+     T  P  S    A++P  PPS  + + +LS   + ++ 
Sbjct: 537  SPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAAT 596

Query: 1303 AHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVS 1362
            + PVS+   AP           P S  S+ S  P  S P S  +P    PS  P   SV 
Sbjct: 597  STPVSSSQSAP-----------PMSPFSSASK-PAASGPLSHPTPLSAPPSSVPLKSSVL 644

Query: 1363 QSSTGTLSSTSFPQNSRSSLPSDLR---TISLPSAGQSAVYQASRVSAVSNSQHYPHRGS 1419
             S +G  +     Q S S +PS ++    I+ P+A   +    S   AV+  Q +  + S
Sbjct: 645  PSPSGRSA-----QGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDS 699

Query: 1420 GGV 1422
              V
Sbjct: 700  DPV 702



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 70/326 (21%), Positives = 127/326 (38%), Gaps = 30/326 (9%)

Query: 1118 SSARTPSSPHKKFSPSHSSMSHLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLRE 1177
            SSA TPS P      +  + S      P DS  ++S+    +E  S++  +P +  +  +
Sbjct: 1478 SSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQ--LPQAPPQTSD 1535

Query: 1178 GGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRY 1237
                  VL +   V+  G  + +        ++ PA    P+  + A+   ++   P + 
Sbjct: 1536 SVKKEPVL-AQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQT 1594

Query: 1238 SYQLLQCDSPRTESQSLLQQSSSPFRGHPTQ--SPGYSYRTTALRP--------GNPPSH 1287
            +       S        ++ SS+P     T   +PG S    A             PP+ 
Sbjct: 1595 AVTAAAISS---AGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAA 1651

Query: 1288 GSSE--SSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPS--- 1342
             SS   + L++ + ++P+       +A  T  P  F  Q  S  ST +  P+ S      
Sbjct: 1652 SSSSAFNQLTNNTATAPSATPVFGQVAAST-APSLFGQQTGSTASTAAATPQVSSSGFSS 1710

Query: 1343 ---SAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPS-DLRTISLPSAGQSA 1398
                  +P + G +    +    QS++   S  SF Q   SS+P+      S P++   +
Sbjct: 1711 PAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGS 1770

Query: 1399 VYQASRVSAVSNS----QHYPHRGSG 1420
            V+ A+  ++ S+S    Q  P+ G G
Sbjct: 1771 VFGAASSTSSSSSFSFGQSSPNTGGG 1796



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 4/142 (2%)

Query: 1268 QSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHS 1327
            +SPG +  T            S+ ++ +S   SSPA P++T SL P  G P  FS    S
Sbjct: 429  KSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSS 488

Query: 1328 GNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLR 1387
              S+ +        SS +  +   P   P++ S    S  +L+    P  + S +     
Sbjct: 489  LKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLA----PTPAASPVAPSAA 544

Query: 1388 TISLPSAGQSAVYQASRVSAVS 1409
            + S  S+G     +++ V +VS
Sbjct: 545  SFSFGSSGFKPTLESTPVPSVS 566



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 45/163 (27%), Positives = 69/163 (42%), Gaps = 14/163 (8%)

Query: 1247 PRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP-------GNPPSHGSSESSLSSTSY 1299
            P   S S   Q ++     P+ +P +     +  P       G+  S  ++   +SS+ +
Sbjct: 1649 PAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGF 1708

Query: 1300 SSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDS-PTS 1358
            SSPA   +   +   T T G  S    S +S  S     S P  ++ P    P+ S PTS
Sbjct: 1709 SSPAFGTTAPGVFGQT-TFGQASVFGQSASSAASVFSF-SQPGFSSVPAFGQPASSTPTS 1766

Query: 1359 DSVS----QSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQS 1397
             S S     SST + SS SF Q+S ++        + P+ GQS
Sbjct: 1767 TSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQS 1809



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 91/371 (24%), Positives = 130/371 (35%), Gaps = 63/371 (16%)

Query: 1041 SLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEAKENSAGGGGDSAQSKSKSAGAG 1100
            SL P G     G  S+        K+         + A  ++    G  ++  S S    
Sbjct: 1171 SLKPSGPTPASGQLSSGDKASGTAKI---------ETAVTSTPSASGQFSKPFSFSPSGT 1221

Query: 1101 QGSSNSVSDTGAHGVQGSSARTPSSPHKK----FSPSHSSMSHLEAVSPSD--SRGTSSS 1154
              +   ++ T +     +   TPS+        FS    S    EA+  S   S  TS+S
Sbjct: 1222 GFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSAS 1281

Query: 1155 HCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPAD 1214
            +  P E  +S                      SS  VA    PS T  S  + K   P  
Sbjct: 1282 NTTPGEPAAS----------------------SSRPVA----PSGTALSTTSSKLETPPS 1315

Query: 1215 GEGPETLSSALSKGATVYSPSRYSY-QLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYS 1273
              G     S+L+ G T+ S S     Q      P  ++ S    S+ P +     S G++
Sbjct: 1316 KLGELLFPSSLA-GETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPS-GFN 1373

Query: 1274 YRTTAL--RPGNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTP----GYFSSQPHS 1327
            +    +  +   PP      SS ++TS + PA   ST S A F   P    G        
Sbjct: 1374 FTAPPVLGKHTEPPV----TSSATTTSVAPPA-ATSTSSTAVFGSLPVTSAGSSGVISFG 1428

Query: 1328 GNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLR 1387
            G S  +     S  S   + T+   +  PT+         T   TSFP  S  SL S   
Sbjct: 1429 GTSLSAGKTSFSFGSQQTNSTVPPSAPPPTT-------AATPLPTSFPTLSFGSLLSSAT 1481

Query: 1388 TISLP-SAGQS 1397
            T SLP SAG+S
Sbjct: 1482 TPSLPMSAGRS 1492



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 49/183 (26%)

Query: 537  EQSNSDVEITT---TTSETPVGEETKTEAPESEVSNSVSNVTIPSTPQSVGVNTRRSSQA 593
            +Q+NS V  +    TT+ TP+     T  P     + +S+ T PS P S G +T  ++ +
Sbjct: 1444 QQTNSTVPPSAPPPTTAATPL----PTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSS 1499

Query: 594  GDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKRQKQANAQQAE----------- 642
                          A P +P      S    S+A  L+ Q+ A   QA            
Sbjct: 1500 --------------ALPEKPGD----SEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEP 1541

Query: 643  -LSQAALEEGG----SNSLV------TPTEAGSLDSSGENRPLTG--SDPTVVSITGSHV 689
             L+Q A+   G    S SLV      TP   G  D+  E  P     S P   ++T + +
Sbjct: 1542 VLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI 1601

Query: 690  NRA 692
            + A
Sbjct: 1602 SSA 1604


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 83/367 (22%), Positives = 142/367 (38%), Gaps = 35/367 (9%)

Query: 1080 ENSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSSPHKKFSPSHSSMSH 1139
            E+S    G S  + S+S+    G+S + +   +    G+S  T S      S + ++ + 
Sbjct: 109  ESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATN- 167

Query: 1140 LEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSP 1199
              + S + S G S++       +SSR    T+ E             S  R    G  + 
Sbjct: 168  --SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTA 225

Query: 1200 TWESNIT----------EKDSDPADGEGPETLS--SALSKGATVYSPSRYSYQLLQCDSP 1247
            T   + T           + S P+ G G  T S  S  S GA   + S  S  +    S 
Sbjct: 226  TNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESS-TVSSGIST 284

Query: 1248 RTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHG------SSESSLSSTSYSS 1301
             T S+S    S +    +   S   S   TA    +  +        +SESS +S+  S+
Sbjct: 285  VTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAST 344

Query: 1302 PAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCPSSAA-------SPTLQGPSD 1354
              +  S+ + +  +      SS   SG ST +N    +  S A+       S T  G S 
Sbjct: 345  ATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGAST 404

Query: 1355 SPTSDSVSQSS-----TGTLSS-TSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAV 1408
            +  S+S + SS     T + SS TS   N+ ++  S + +    +A  + ++  S  ++ 
Sbjct: 405  ATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAST 464

Query: 1409 SNSQHYP 1415
            + S+  P
Sbjct: 465  AVSEAKP 471



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 86/351 (24%), Positives = 129/351 (36%), Gaps = 33/351 (9%)

Query: 1081 NSAGGGGDSAQSKSKSAGAGQGSSNSVSDTGAHGVQGSSARTPSS-----PHKKFSPSHS 1135
            ++A   G S  S   S     GSS  V+  G   V  S   T SS      + +FS   S
Sbjct: 43   STATNSGSSVTSSGVSTATISGSS--VTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSS 100

Query: 1136 SMS-----HLEAVSPSDSRGTSSSHCRPQENISSRWMVPTSVERLREGGSIPKVLRSSVR 1190
             +S          S   S  T+S    P    S+      S       G+       S  
Sbjct: 101  GISIATNSESSTTSSGASTATNSESSTPSSGAST---ATNSDSSTTSSGASTATNSDSST 157

Query: 1191 VAQKGEPSPTWESNITEKDSDPADGEGPETLSSALSKGATVYSPSRYSYQLLQCDSP-RT 1249
             + +   +   ES+ T   +  A      T+SS  S      S +  S      +S  RT
Sbjct: 158  TSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRT 217

Query: 1250 ESQSLLQQSSSPFRGHPTQSPGYSYRTTALRPGNPPSHGSSESSLSSTSYSSPAHPVSTD 1309
             S      ++S      T S G S  T +         G++ +S SST+ S      +++
Sbjct: 218  TSNGAGTATNSE---SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSE 274

Query: 1310 SLAPFTG---TPGYFSSQPHSGNSTGSNLPRRSCPSSAASPTLQGPSDSPTSDSVSQSST 1366
            S    +G        SS P SG +T +N    +  S A + T    SDS T+ S + ++T
Sbjct: 275  SSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTAT---NSDSSTTSSGASTAT 331

Query: 1367 GTLSST-----SFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQ 1412
             + SST     S   NS SS  S   + +  S   +    +S  S  +NS+
Sbjct: 332  NSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT---SSGTSTATNSE 379



 Score = 34.7 bits (78), Expect = 0.68
 Identities = 40/222 (18%), Positives = 80/222 (36%), Gaps = 4/222 (1%)

Query: 1222 SSALSKGATVYSPSRYSYQLLQCDSPRTESQSLLQQSSSPFRGHPTQSPGYSYRTTALRP 1281
            SS  S G ++ + S +        +      S +    S      + +      T     
Sbjct: 65   SSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSE 124

Query: 1282 GNPPSHGSSESSLSSTSYSSPAHPVSTDSLAPFTGTPGYFSSQPHSGNSTGSNLPRRSCP 1341
             + PS G+S ++ S +S +S     +T+S +  T +    ++   S  ++       +  
Sbjct: 125  SSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184

Query: 1342 SSAASPTLQGPSDSPTSDSVSQSSTGTLSSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQ 1401
            SS  S      ++S +S + S +ST T S +    N   +  +   + +   A  +   +
Sbjct: 185  SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244

Query: 1402 ASRVSA----VSNSQHYPHRGSGGVHQYRLQPLQGSGVKTQT 1439
            +S  S+     +NS+        G           SG+ T T
Sbjct: 245  SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT 286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.125    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,731,756
Number of Sequences: 37866
Number of extensions: 3418859
Number of successful extensions: 29490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 277
Number of HSP's successfully gapped in prelim test: 1161
Number of HSP's that attempted gapping in prelim test: 19504
Number of HSP's gapped (non-prelim): 8365
length of query: 1442
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1327
effective length of database: 13,892,928
effective search space: 18435915456
effective search space used: 18435915456
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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