Search of human proteins with 31652259

Search of human proteins with 31652259

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31652259 melanoma ubiquitous mutated protein [Homo sapiens]
         (711 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31652259 melanoma ubiquitous mutated protein [Homo sapiens]       1436   0.0  
gi|24432077 melanoma associated antigen (mutated) 1-like 1 [Homo...   463   e-130
gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]           337   2e-92
gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]           337   2e-92
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]           337   2e-92
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]           337   2e-92
gi|146134388 YLP motif containing 1 [Homo sapiens]                     50   6e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  49   2e-05
gi|168229174 RNA binding motif protein 27 [Homo sapiens]               48   4e-05
gi|33286446 opioid growth factor receptor [Homo sapiens]               46   1e-04
gi|153792074 proline rich 12 [Homo sapiens]                            46   1e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   45   2e-04
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    44   4e-04
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    44   4e-04
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    44   4e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   4e-04
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        44   4e-04
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       44   4e-04
gi|55741677 SET domain containing 1A [Homo sapiens]                    44   5e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        44   5e-04
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    43   9e-04
gi|195963410 MEF2 activating motif and SAP domain containing tra...    42   0.002
gi|32698970 MEF2 activating motif and SAP domain containing tran...    42   0.002
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    42   0.002
gi|226371735 iroquois homeobox 3 [Homo sapiens]                        42   0.002
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     42   0.002
gi|78499633 phospholipase C, eta 2 [Homo sapiens]                      42   0.002
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              42   0.002
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       41   0.003
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa...    41   0.003

>gi|31652259 melanoma ubiquitous mutated protein [Homo sapiens]
          Length = 711

 Score = 1436 bits (3717), Expect = 0.0
 Identities = 711/711 (100%), Positives = 711/711 (100%)

Query: 1   MMADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEIL 60
           MMADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEIL
Sbjct: 1   MMADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEIL 60

Query: 61  EKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSL 120
           EKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSL
Sbjct: 61  EKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSL 120

Query: 121 RGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKG 180
           RGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKG
Sbjct: 121 RGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKG 180

Query: 181 LRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDT 240
           LRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDT
Sbjct: 181 LRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDT 240

Query: 241 ERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPA 300
           ERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPA
Sbjct: 241 ERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPA 300

Query: 301 KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRC 360
           KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRC
Sbjct: 301 KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRC 360

Query: 361 LPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKH 420
           LPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKH
Sbjct: 361 LPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKH 420

Query: 421 KKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQARE 480
           KKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQARE
Sbjct: 421 KKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQARE 480

Query: 481 DFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKG 540
           DFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKG
Sbjct: 481 DFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKG 540

Query: 541 SPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPS 600
           SPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPS
Sbjct: 541 SPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPS 600

Query: 601 RWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVL 660
           RWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVL
Sbjct: 601 RWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVL 660

Query: 661 LPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR 711
           LPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR
Sbjct: 661 LPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR 711


>gi|24432077 melanoma associated antigen (mutated) 1-like 1 [Homo
           sapiens]
          Length = 637

 Score =  463 bits (1191), Expect = e-130
 Identities = 285/678 (42%), Positives = 394/678 (58%), Gaps = 66/678 (9%)

Query: 4   DAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKS 63
           +++YVLC W+ +LWPAKVL+R+ TS+ +KR+K + L VQILSL+EKIK+ STE +IL KS
Sbjct: 2   ESEYVLCDWKDQLWPAKVLSRSETSSNSKRKKAFSLEVQILSLDEKIKLDSTETKILNKS 61

Query: 64  QIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGK 123
           QIEAIA+SL  Q+E  A P EE AY RSL+VAL +L+E +  SQ S++         +  
Sbjct: 62  QIEAIAASLGLQSEDSAPPTEETAYGRSLKVALGILNERTNLSQASTSDEEEITMLSQNV 121

Query: 124 PMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRK 183
           P +   SP          GD+ G         C+  S  S  +   D            K
Sbjct: 122 PQKQSDSP-PHKKYRKDEGDLPGCLEERENSACLLASSESDDSLYDD------------K 168

Query: 184 SENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERD 243
           S+ P     +P          S +  K           S Q +S C    SLSED+ E++
Sbjct: 169 SQAPTMVDTIP----------SEVETK-----------SLQNSSWCETFPSLSEDNDEKE 207

Query: 244 MGSKGGSWAAPSLPSGVREDDPCANAEGHDPGL-PLGS--LTAPPAPE------------ 288
             +K    A  S+ S V+E+  C   E   P L PL S  L  P A +            
Sbjct: 208 NKNKIDISAVMSVHSAVKEESACVKDEKFAPPLSPLSSDMLIMPKALKEESEDTCLETLA 267

Query: 289 -PSACS-------EPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTP 340
            PS CS       +PGE P+   P LD SQ  P+++ E  AA       PG   RE    
Sbjct: 268 VPSECSAFSENIEDPGEGPS--NPCLDTSQNQPSMESEMGAAAC-----PGSCSRECEVS 320

Query: 341 RSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEES-MGSNSMRSILEEDEEDEEPP 399
            S +      SH  + + R     D ++LE+E Q+S++S + S    S+L++DEEDEE P
Sbjct: 321 FSASNPVWDYSHLMS-SERNFQRLDFEELEEEGQASDKSLLPSRINLSLLDDDEEDEELP 379

Query: 400 RVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVS 459
           R +L++E   FE GM+VW K++KYPFWPAV+KS+R++++KASVL++E +MN + KG  V+
Sbjct: 380 RFILHYETHPFETGMIVWFKYQKYPFWPAVIKSIRRKERKASVLFVEANMNSEKKGIRVN 439

Query: 460 LKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISY 519
            + LK FDCKEKQ L+++ARED+++ I WC+SLI DYRVR+GCGSF GS LEYYAADISY
Sbjct: 440 FRRLKKFDCKEKQMLVDKAREDYSESIDWCISLICDYRVRIGCGSFTGSLLEYYAADISY 499

Query: 520 PVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEY 579
           PVRK  +QD    K P+L      EP+      ++   +K+LPDR +AARDRAN+ LV++
Sbjct: 500 PVRKETKQDTFRNKFPKLHNEDAREPMAVTSQTKKMSFQKILPDRMKAARDRANKNLVDF 559

Query: 580 IVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQE 639
           IV AKG E+HL AI+   K SRWL++FL+++++  C+ETY EDE QLD VVKYLQ V  +
Sbjct: 560 IVNAKGTENHLLAIVNGTKGSRWLKSFLNANRFTPCIETYFEDEDQLDEVVKYLQEVCNQ 619

Query: 640 VGAKVLQRTNGDRIRFIL 657
           +   +      D+I+FIL
Sbjct: 620 IDQIMPTWIKDDKIKFIL 637


>gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score =  337 bits (865), Expect = 2e-92
 Identities = 199/490 (40%), Positives = 286/490 (58%), Gaps = 26/490 (5%)

Query: 224  QKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTA 283
            Q    C +  +LS    E+    +  +    SLP  V E+          PGL   +  A
Sbjct: 1584 QSPRACQDSLTLSRHVCEKKGKKRANASTLMSLPPTVTEEGASL-----PPGL---TSPA 1635

Query: 284  PPA-PEPSACSEPGECPA---KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVT 339
            PPA  E +  S P +  A   +  P     Q P     +P  AG A S G     R+   
Sbjct: 1636 PPALKEETQDSRPKKALAASPESSPFSGNIQDPGEGAWKPGWAGMAASSGS----RQHRL 1691

Query: 340  PRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED-EEDEEP 398
            P S+ RL        A+  R  P PD Q+  +  Q+  ++  +N + +I     ++D +P
Sbjct: 1692 P-SSLRL--------ANRKRKRPGPDFQRRPQGPQTPGDAKLANPVTTIQRAGGKQDGQP 1742

Query: 399  PRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTV 458
            P +    EP   E G +VW K + +PFWPAVVKSV   DK A VL +E +++   +G  V
Sbjct: 1743 PSLAFPQEPHPIERGTMVWFKFQDHPFWPAVVKSVSNTDKTARVLLLEANLHHGKRGIQV 1802

Query: 459  SLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADIS 518
             L+ LKH DCKEK+ LL +A++ + Q + WC SLI+ YR  L  GSF GSFL+YYAADIS
Sbjct: 1803 PLRRLKHLDCKEKEKLLKRAQKAYKQSVNWCFSLISHYREGLVRGSFRGSFLDYYAADIS 1862

Query: 519  YPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVE 578
            YP+R++IQ+  L    P+++ G  E+      LG ++PC+K+LPDR RA+ DR NQKLV+
Sbjct: 1863 YPIRRAIQEGDLQIDFPKVNYGDLEDWEEETSLGGKRPCKKILPDRMRASWDRDNQKLVD 1922

Query: 579  YIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQ 638
            +IV+ KGA+ HL  IL+ RK SRWL  FL   + + C+ETYLED+ QL++V K+LQ +Y+
Sbjct: 1923 FIVRRKGADPHLLDILQGRKQSRWLTAFLKPHRDLHCIETYLEDDDQLEVVAKHLQEIYK 1982

Query: 639  EVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIF 698
            ++    L     D++ F+L+VLLPEA+IC I+A+D +DYK AEEKY++GP + YREKE+F
Sbjct: 1983 QIDKARLTLIRDDKVNFVLEVLLPEAMICTIAALDGLDYKAAEEKYLRGPPVHYREKELF 2042

Query: 699  DNQLLEERNR 708
            D  +L++  R
Sbjct: 2043 DRNILKKARR 2052



 Score =  113 bits (282), Expect = 7e-25
 Identities = 75/189 (39%), Positives = 102/189 (53%), Gaps = 31/189 (16%)

Query: 4   DAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKS 63
           D++YVLC W+ RLWPAKVL    TS K K  K   L VQIL+++EKIKVKST+V+   K 
Sbjct: 2   DSEYVLCSWKGRLWPAKVLCTRGTSPKTKPEKAISLEVQILAVDEKIKVKSTDVKTPTKF 61

Query: 64  QIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGK 123
           ++E IA+S A+Q ++ A   E++ YR +LRVAL++L E       ++ G GR       K
Sbjct: 62  EMEDIAASAAAQTKLGAPLREKMGYRGTLRVALEILKE------RTNLGGGR-------K 108

Query: 124 PMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRK 183
           P E                  L S+ P +    V +  +SS   E D  CK D ++ L K
Sbjct: 109 PHE------------------LESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGK 150

Query: 184 SENPRGPLV 192
            ENP  P V
Sbjct: 151 RENPSSPTV 159


>gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score =  337 bits (865), Expect = 2e-92
 Identities = 199/490 (40%), Positives = 286/490 (58%), Gaps = 26/490 (5%)

Query: 224  QKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTA 283
            Q    C +  +LS    E+    +  +    SLP  V E+          PGL   +  A
Sbjct: 1584 QSPRACQDSLTLSRHVCEKKGKKRANASTLMSLPPTVTEEGASL-----PPGL---TSPA 1635

Query: 284  PPA-PEPSACSEPGECPA---KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVT 339
            PPA  E +  S P +  A   +  P     Q P     +P  AG A S G     R+   
Sbjct: 1636 PPALKEETQDSRPKKALAASPESSPFSGNIQDPGEGAWKPGWAGMAASSGS----RQHRL 1691

Query: 340  PRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED-EEDEEP 398
            P S+ RL        A+  R  P PD Q+  +  Q+  ++  +N + +I     ++D +P
Sbjct: 1692 P-SSLRL--------ANRKRKRPGPDFQRRPQGPQTPGDAKLANPVTTIQRAGGKQDGQP 1742

Query: 399  PRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTV 458
            P +    EP   E G +VW K + +PFWPAVVKSV   DK A VL +E +++   +G  V
Sbjct: 1743 PSLAFPQEPHPIERGTMVWFKFQDHPFWPAVVKSVSNTDKTARVLLLEANLHHGKRGIQV 1802

Query: 459  SLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADIS 518
             L+ LKH DCKEK+ LL +A++ + Q + WC SLI+ YR  L  GSF GSFL+YYAADIS
Sbjct: 1803 PLRRLKHLDCKEKEKLLKRAQKAYKQSVNWCFSLISHYREGLVRGSFRGSFLDYYAADIS 1862

Query: 519  YPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVE 578
            YP+R++IQ+  L    P+++ G  E+      LG ++PC+K+LPDR RA+ DR NQKLV+
Sbjct: 1863 YPIRRAIQEGDLQIDFPKVNYGDLEDWEEETSLGGKRPCKKILPDRMRASWDRDNQKLVD 1922

Query: 579  YIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQ 638
            +IV+ KGA+ HL  IL+ RK SRWL  FL   + + C+ETYLED+ QL++V K+LQ +Y+
Sbjct: 1923 FIVRRKGADPHLLDILQGRKQSRWLTAFLKPHRDLHCIETYLEDDDQLEVVAKHLQEIYK 1982

Query: 639  EVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIF 698
            ++    L     D++ F+L+VLLPEA+IC I+A+D +DYK AEEKY++GP + YREKE+F
Sbjct: 1983 QIDKARLTLIRDDKVNFVLEVLLPEAMICTIAALDGLDYKAAEEKYLRGPPVHYREKELF 2042

Query: 699  DNQLLEERNR 708
            D  +L++  R
Sbjct: 2043 DRNILKKARR 2052



 Score =  113 bits (282), Expect = 7e-25
 Identities = 75/189 (39%), Positives = 102/189 (53%), Gaps = 31/189 (16%)

Query: 4   DAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKS 63
           D++YVLC W+ RLWPAKVL    TS K K  K   L VQIL+++EKIKVKST+V+   K 
Sbjct: 2   DSEYVLCSWKGRLWPAKVLCTRGTSPKTKPEKAISLEVQILAVDEKIKVKSTDVKTPTKF 61

Query: 64  QIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGK 123
           ++E IA+S A+Q ++ A   E++ YR +LRVAL++L E       ++ G GR       K
Sbjct: 62  EMEDIAASAAAQTKLGAPLREKMGYRGTLRVALEILKE------RTNLGGGR-------K 108

Query: 124 PMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRK 183
           P E                  L S+ P +    V +  +SS   E D  CK D ++ L K
Sbjct: 109 PHE------------------LESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGK 150

Query: 184 SENPRGPLV 192
            ENP  P V
Sbjct: 151 RENPSSPTV 159


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score =  337 bits (865), Expect = 2e-92
 Identities = 199/490 (40%), Positives = 286/490 (58%), Gaps = 26/490 (5%)

Query: 224  QKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTA 283
            Q    C +  +LS    E+    +  +    SLP  V E+          PGL   +  A
Sbjct: 1457 QSPRACQDSLTLSRHVCEKKGKKRANASTLMSLPPTVTEEGASL-----PPGL---TSPA 1508

Query: 284  PPA-PEPSACSEPGECPA---KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVT 339
            PPA  E +  S P +  A   +  P     Q P     +P  AG A S G     R+   
Sbjct: 1509 PPALKEETQDSRPKKALAASPESSPFSGNIQDPGEGAWKPGWAGMAASSGS----RQHRL 1564

Query: 340  PRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED-EEDEEP 398
            P S+ RL        A+  R  P PD Q+  +  Q+  ++  +N + +I     ++D +P
Sbjct: 1565 P-SSLRL--------ANRKRKRPGPDFQRRPQGPQTPGDAKLANPVTTIQRAGGKQDGQP 1615

Query: 399  PRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTV 458
            P +    EP   E G +VW K + +PFWPAVVKSV   DK A VL +E +++   +G  V
Sbjct: 1616 PSLAFPQEPHPIERGTMVWFKFQDHPFWPAVVKSVSNTDKTARVLLLEANLHHGKRGIQV 1675

Query: 459  SLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADIS 518
             L+ LKH DCKEK+ LL +A++ + Q + WC SLI+ YR  L  GSF GSFL+YYAADIS
Sbjct: 1676 PLRRLKHLDCKEKEKLLKRAQKAYKQSVNWCFSLISHYREGLVRGSFRGSFLDYYAADIS 1735

Query: 519  YPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVE 578
            YP+R++IQ+  L    P+++ G  E+      LG ++PC+K+LPDR RA+ DR NQKLV+
Sbjct: 1736 YPIRRAIQEGDLQIDFPKVNYGDLEDWEEETSLGGKRPCKKILPDRMRASWDRDNQKLVD 1795

Query: 579  YIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQ 638
            +IV+ KGA+ HL  IL+ RK SRWL  FL   + + C+ETYLED+ QL++V K+LQ +Y+
Sbjct: 1796 FIVRRKGADPHLLDILQGRKQSRWLTAFLKPHRDLHCIETYLEDDDQLEVVAKHLQEIYK 1855

Query: 639  EVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIF 698
            ++    L     D++ F+L+VLLPEA+IC I+A+D +DYK AEEKY++GP + YREKE+F
Sbjct: 1856 QIDKARLTLIRDDKVNFVLEVLLPEAMICTIAALDGLDYKAAEEKYLRGPPVHYREKELF 1915

Query: 699  DNQLLEERNR 708
            D  +L++  R
Sbjct: 1916 DRNILKKARR 1925



 Score =  113 bits (282), Expect = 7e-25
 Identities = 75/189 (39%), Positives = 102/189 (53%), Gaps = 31/189 (16%)

Query: 4   DAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKS 63
           D++YVLC W+ RLWPAKVL    TS K K  K   L VQIL+++EKIKVKST+V+   K 
Sbjct: 2   DSEYVLCSWKGRLWPAKVLCTRGTSPKTKPEKAISLEVQILAVDEKIKVKSTDVKTPTKF 61

Query: 64  QIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGK 123
           ++E IA+S A+Q ++ A   E++ YR +LRVAL++L E       ++ G GR       K
Sbjct: 62  EMEDIAASAAAQTKLGAPLREKMGYRGTLRVALEILKE------RTNLGGGR-------K 108

Query: 124 PMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRK 183
           P E                  L S+ P +    V +  +SS   E D  CK D ++ L K
Sbjct: 109 PHE------------------LESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGK 150

Query: 184 SENPRGPLV 192
            ENP  P V
Sbjct: 151 RENPSSPTV 159


>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2028

 Score =  337 bits (864), Expect = 2e-92
 Identities = 199/492 (40%), Positives = 286/492 (58%), Gaps = 30/492 (6%)

Query: 224  QKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTA 283
            Q    C +  +LS    E+    +  +    SLP  V E+            LP G LT+
Sbjct: 1551 QSPRACQDSLTLSRHVCEKKGKKRANASTLMSLPPTVTEEGA---------SLPPG-LTS 1600

Query: 284  PPAP---EPSACSEPGECPA---KKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRES 337
            P  P   E +  S P +  A   +  P     Q P     +P  AG A S G     R+ 
Sbjct: 1601 PAPPTLKEETQDSRPKKALAASPESSPFSGNIQDPGEGAWKPGWAGMAASSGS----RQH 1656

Query: 338  VTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED-EEDE 396
              P S+ RL        A+  R  P PD Q+  +  Q+  ++  +N + +I     ++D 
Sbjct: 1657 RLP-SSLRL--------ANRKRKRPGPDFQRRPQGPQTPGDAKLANPVTTIQRAGGKQDG 1707

Query: 397  EPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGF 456
            +PP +    EP   E G +VW K + +PFWPAVVKSV   DK A VL +E +++   +G 
Sbjct: 1708 QPPSLAFPQEPHPIERGTMVWFKFQDHPFWPAVVKSVSNTDKTARVLLLEANLHHGKRGI 1767

Query: 457  TVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAAD 516
             V L+ LKH DCKEK+ LL +A++ + Q + WC SLI+ YR  L  GSF GSFL+YYAAD
Sbjct: 1768 QVPLRRLKHLDCKEKEKLLKRAQKAYKQSVNWCFSLISHYREGLVRGSFRGSFLDYYAAD 1827

Query: 517  ISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKL 576
            ISYP+R++IQ+  L    P+++ G  E+      LG ++PC+K+LPDR RA+ DR NQKL
Sbjct: 1828 ISYPIRRAIQEGDLQIDFPKVNYGDLEDWEEETSLGGKRPCKKILPDRMRASWDRDNQKL 1887

Query: 577  VEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGV 636
            V++IV+ KGA+ HL  IL+ RK SRWL  FL   + + C+ETYLED+ QL++V K+LQ +
Sbjct: 1888 VDFIVRRKGADPHLLDILQGRKQSRWLTAFLKPHRDLHCIETYLEDDDQLEVVAKHLQEI 1947

Query: 637  YQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKE 696
            Y+++    L     D++ F+L+VLLPEA+IC I+A+D +DYK AEEKY++GP + YREKE
Sbjct: 1948 YKQIDKARLTLIRDDKVNFVLEVLLPEAMICTIAALDGLDYKAAEEKYLRGPPVHYREKE 2007

Query: 697  IFDNQLLEERNR 708
            +FD  +L++  R
Sbjct: 2008 LFDRNILKKARR 2019



 Score =  113 bits (282), Expect = 7e-25
 Identities = 75/189 (39%), Positives = 102/189 (53%), Gaps = 31/189 (16%)

Query: 4   DAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKS 63
           D++YVLC W+ RLWPAKVL    TS K K  K   L VQIL+++EKIKVKST+V+   K 
Sbjct: 2   DSEYVLCSWKGRLWPAKVLCTRGTSPKTKPEKAISLEVQILAVDEKIKVKSTDVKTPTKF 61

Query: 64  QIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGK 123
           ++E IA+S A+Q ++ A   E++ YR +LRVAL++L E       ++ G GR       K
Sbjct: 62  EMEDIAASAAAQTKLGAPLREKMGYRGTLRVALEILKE------RTNLGGGR-------K 108

Query: 124 PMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRK 183
           P E                  L S+ P +    V +  +SS   E D  CK D ++ L K
Sbjct: 109 PHE------------------LESTTPSQLSQKVPEKPASSVPREDDWRCKGDLRRSLGK 150

Query: 184 SENPRGPLV 192
            ENP  P V
Sbjct: 151 RENPSSPTV 159


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 13/113 (11%)

Query: 254 PSLPSGVREDDPCANAEGHDPGLP--LGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQR 311
           PSLP+ V             PG+P  L S   PP   P + S  G  P    P L  +  
Sbjct: 567 PSLPTSVPP-----------PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615

Query: 312 PPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCP 364
           PP + L P+++   P   P PG  + + P+ TA   PP S + +      P P
Sbjct: 616 PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 1/91 (1%)

Query: 274 PGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPG 333
           P +P   +  P    P     P   P    P L  +  PP +   P+   + P+  P PG
Sbjct: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP-PPVMPPSLPTSVPPPG 577

Query: 334 PRESVTPRSTARLGPPPSHASADATRCLPCP 364
              S++      + PPPS +SA     LP P
Sbjct: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPP 608



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 7/126 (5%)

Query: 274 PGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPG 333
           PGL    L +PP   P     PG      +  +   Q PP+      +    P   P P 
Sbjct: 136 PGLVPMELESPPESPPVP---PGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSP- 191

Query: 334 PRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDE 393
              S +P S + L P PS++S+ ++       SQ      Q+S         +S L    
Sbjct: 192 ---SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP 248

Query: 394 EDEEPP 399
               PP
Sbjct: 249 PPSAPP 254



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 7/83 (8%)

Query: 274 PGLPLGSLTAPPAPE--PSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGP- 330
           P LP  SL  P  P   P+    PG  P    P L  S  PP +     +AG  P   P 
Sbjct: 536 PVLP-PSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPP 594

Query: 331 ---GPGPRESVTPRSTARLGPPP 350
                GP   + P S +   PPP
Sbjct: 595 SLSSAGPPPVLPPPSLSSTAPPP 617


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 11/140 (7%)

Query: 252  AAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQR 311
            A   LPSG     P  +     P     +L  PP   PS  + P + P+   P L    +
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPA----ALAKPPGTPPSLGASPAKPPSPGAPALHVPAK 1341

Query: 312  PPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEK 371
            PP       AA AAP     P P E  +P  +AR        SA     L   + +  ++
Sbjct: 1342 PPRAAAAAAAAAAAP-----PAPPEGASPGDSAR--QKLEETSACLAAALQAVEEKIRQE 1394

Query: 372  ECQSSEESMGSNSMRSILEE 391
            + Q   +S    S  SIL++
Sbjct: 1395 DAQGPRDSAAEKSTGSILDD 1414



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 7/81 (8%)

Query: 277  PLGSLTAPPAPEPSACSEPGE-CPAKKR-----PRLDGSQRPPAVQLEPMAAGAA-PSPG 329
            P+  L   P P       PG   P  KR     P +     PP    +P+ A A  PS  
Sbjct: 1235 PVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGS 1294

Query: 330  PGPGPRESVTPRSTARLGPPP 350
             GP P  S   +  A L  PP
Sbjct: 1295 AGPSPAPSPARQPPAALAKPP 1315



 Score = 30.0 bits (66), Expect = 7.7
 Identities = 28/104 (26%), Positives = 33/104 (31%), Gaps = 4/104 (3%)

Query: 254 PSLPSGVREDDPCANAEGHDPGLPLGSLTAPPA--PEPSACSEPGECPAKKRPRLDGSQR 311
           P  P+  R   P A    H P      +   P   P       P   P     R      
Sbjct: 777 PQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVL 836

Query: 312 PPAVQLE--PMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHA 353
           P  V+ E  P A G AP P P   P   + P + A  G P   A
Sbjct: 837 PQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRA 880


>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
          Length = 1060

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 39/147 (26%), Positives = 56/147 (38%), Gaps = 22/147 (14%)

Query: 264 DPCANAEGHDP----GLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEP 319
           D C    G+DP     + L S+   P P P     P                PP + + P
Sbjct: 292 DLCQFDHGNDPLVVDEVALPSMIPFPPPPPGLPPPP----------------PPGMLMPP 335

Query: 320 MAA-GAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEE 378
           M   G  P PGPGPGP     P  + RL  P  H     +  LP P     +    +S +
Sbjct: 336 MPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPITQSSLINSRD 395

Query: 379 SMGSNSMRSILEEDEEDEEP-PRVLLY 404
             G++++ ++         P P+ LLY
Sbjct: 396 QPGTSAVPNLASVGTRLPPPLPQNLLY 422


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 51/167 (30%), Positives = 61/167 (36%), Gaps = 21/167 (12%)

Query: 176 DHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSL 235
           D  +  RK +   G     A GGAQ             LA     +   KA    NG   
Sbjct: 453 DKVRKRRKVDEGAGDSAAVASGGAQ----------TLALAGSPAPSGHPKAGHSENGV-- 500

Query: 236 SEDDTERDMGSKGGSWAAPS-----LPSGVREDDPCANAEGHDPG-LPLGSLTAPPAPEP 289
            E+DTE   G K G+  +PS      P+G   D+P A +    PG  P G     PA  P
Sbjct: 501 -EEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEP-AESPSETPGPRPAGPAGDEPAESP 558

Query: 290 SACSEPGEC-PAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPR 335
           S    P    PA   P    S+ P      P     A SP   PGPR
Sbjct: 559 SETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/141 (27%), Positives = 52/141 (36%), Gaps = 12/141 (8%)

Query: 265  PCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGA 324
            P AN+ G  P  PL     PP P P+   +P   P    P+      PP V   P +   
Sbjct: 1440 PSANSNG-TPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP 1498

Query: 325  APSPGPGPGPRES---VTPRSTARLGPPPSHASADA--------TRCLPCPDSQKLEKEC 373
             P P P P    S     P + A L  PP   +A +        TR L     Q+    C
Sbjct: 1499 PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVC 1558

Query: 374  QSSEESMGSNSMRSILEEDEE 394
              ++E  G +    I  E +E
Sbjct: 1559 GETDEEAGESGGEGIFRERDE 1579



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 7/89 (7%)

Query: 262  EDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMA 321
            +D P A  +  D   P G   AP A  P     P   P       +G+  PP ++ +P  
Sbjct: 1406 DDPPLAGPK--DTSTPDGPPLAPAAAVPG----PPPLPGLPSANSNGTPEPPLLEEKPPP 1459

Query: 322  AGAAPSPGPGPGPRESVTPRSTARLGPPP 350
                P+P P P P     P   A   PPP
Sbjct: 1460 T-PPPAPTPQPQPPPPPPPPQPALPSPPP 1487


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 55/188 (29%), Positives = 71/188 (37%), Gaps = 45/188 (23%)

Query: 257  PSGVREDDPCAN---AEGHDPGLPLGSLTAP---PAPEPSACSEPGEC-PAKKRPRLDGS 309
            PS      PC +   +EG  P LP+    AP   P P PSA S P +  PA   P+ D +
Sbjct: 1037 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGP-PSAQSSPIDAQPATPLPQKDPA 1095

Query: 310  QR------PPAVQLEPMAAGAAPSPGPGPGPRESVTPR-----------STAR------- 345
            Q       PP   + P    A P   P P  R   +P+           STAR       
Sbjct: 1096 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1155

Query: 346  --LGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED----EEDEEPP 399
              +  P SHA A A R  P       E + ++SE S GS  +   L+       +   PP
Sbjct: 1156 GVISAPQSHARASAGRLTP-------ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208

Query: 400  RVLLYHEP 407
                  EP
Sbjct: 1209 PAQRLQEP 1216



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 34/132 (25%), Positives = 46/132 (34%), Gaps = 36/132 (27%)

Query: 254  PSLPSGVREDDPCANAEGHDP-GLPLGSLTAPP------APEPSACSEPGECPAKKRPRL 306
            P  PSG  +  P A   G  P G      T PP      AP+  A +  G    + + + 
Sbjct: 1121 PPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKT 1180

Query: 307  DGSQR----------------------PPAVQL-EPMAAGAAPSPGPGPGPRESVTPRST 343
              + +                      PPA +L EP+   AAP P  GP P     P+  
Sbjct: 1181 SETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQ-- 1238

Query: 344  ARLGPPPSHASA 355
                PPP   S+
Sbjct: 1239 ----PPPRSRSS 1246


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 32/126 (25%), Positives = 44/126 (34%), Gaps = 11/126 (8%)

Query: 253 APSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRP 312
           +P L       D    A    P +P+ +  + P P P     P   PA           P
Sbjct: 105 SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA-----------P 153

Query: 313 PAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKE 372
            A  +    A A  +P P P P  +  P   A   P P+ A A A    P PD+   E  
Sbjct: 154 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 213

Query: 373 CQSSEE 378
            Q + +
Sbjct: 214 EQGANQ 219


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 32/126 (25%), Positives = 44/126 (34%), Gaps = 11/126 (8%)

Query: 253 APSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRP 312
           +P L       D    A    P +P+ +  + P P P     P   PA           P
Sbjct: 105 SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA-----------P 153

Query: 313 PAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKE 372
            A  +    A A  +P P P P  +  P   A   P P+ A A A    P PD+   E  
Sbjct: 154 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 213

Query: 373 CQSSEE 378
            Q + +
Sbjct: 214 EQGANQ 219


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 32/126 (25%), Positives = 44/126 (34%), Gaps = 11/126 (8%)

Query: 253 APSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRP 312
           +P L       D    A    P +P+ +  + P P P     P   PA           P
Sbjct: 116 SPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPA-----------P 164

Query: 313 PAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKE 372
            A  +    A A  +P P P P  +  P   A   P P+ A A A    P PD+   E  
Sbjct: 165 VAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESA 224

Query: 373 CQSSEE 378
            Q + +
Sbjct: 225 EQGANQ 230


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/122 (31%), Positives = 51/122 (41%), Gaps = 10/122 (8%)

Query: 252 AAPSLPSGVREDDPCANAEGHDPGLPL-GSLTAPPAPEPSACSEPGEC-------PAKKR 303
           AA +L + V    P A A G  P  P  G+  A P P P+  + PG         P+ +R
Sbjct: 54  AAGALGNHVVSGSP-AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR 112

Query: 304 PRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGP-PPSHASADATRCLP 362
           P +     PPA +L P   G+A S  P P           A  GP  P+  +A A R  P
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172

Query: 363 CP 364
            P
Sbjct: 173 GP 174



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 11/95 (11%)

Query: 265 PCANAEGHDPGLPLGSLTA----PPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPM 320
           P A A    P  P  +  A    PP P P+  + P   PA   P    +  PPA      
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP-PTAAPAVPPPAAAQNGG 307

Query: 321 AAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASA 355
           +AGAAP+P P  G    V+ +      P P  A+A
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQ------PGPGAAAA 336



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 5/60 (8%)

Query: 310 QRPPAVQLEPMAAGAAPSPGPGPGPRESVT-----PRSTARLGPPPSHASADATRCLPCP 364
           Q PP V      A AAPSP   P P          P + A L  PP H +   T     P
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 8/77 (10%)

Query: 285 PAPEPSACSEPGECP---AKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPG-----PRE 336
           P P+P+A     + P       P    +  PPA       A A P P P P      P  
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGH 286

Query: 337 SVTPRSTARLGPPPSHA 353
              P + A   PPP+ A
Sbjct: 287 PAGPPTAAPAVPPPAAA 303



 Score = 30.4 bits (67), Expect = 5.9
 Identities = 15/45 (33%), Positives = 18/45 (40%)

Query: 315 VQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATR 359
           +Q  P    AAP     P P  +  P + A   PPP  A A   R
Sbjct: 238 IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLAR 282


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 72/350 (20%), Positives = 122/350 (34%), Gaps = 33/350 (9%)

Query: 25  TATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLE 84
           TA   + ++ +E  L      L+ + ++K+   +I+EK   +A+   L  ++    +  E
Sbjct: 312 TALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEK---DAMIKVLQQRSRKEPSKTE 368

Query: 85  ELAYRRSLRVALDVLSEGSIWSQESSAGTG-------RADRSLRGKPMEHVSSPCDSNSS 137
           +L+  R  +  + + + GS     SS  TG       R D+S +G            +  
Sbjct: 369 QLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKG------------SLG 416

Query: 138 SLPRGDVLGSSRPHRRRPCVQQS-LSSSFTCEKDPECKVDHKKGLRKSENPR-GPLVLPA 195
            L  GD      P    P    + L S+ +     +C    ++G   ++     P+ +PA
Sbjct: 417 ILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPA 476

Query: 196 G-GGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAP 254
               A   +         T         A  A+     ++     T     +     AA 
Sbjct: 477 PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAG 536

Query: 255 SLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPA 314
            +P+        A A        +    A PAP P+    P   PA  +     +  P  
Sbjct: 537 QIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQ-----ASAPAQ 591

Query: 315 VQLEPMAAGAAPSPGPGPGP--RESVTPRSTARLGPPPSHASADATRCLP 362
            Q    A   AP+P P P P   ++  P S A  GP P   S  +  C P
Sbjct: 592 TQAPTSAPAVAPTPAPTPTPAVAQAEVPASPA-TGPGPHRLSIPSLTCNP 640


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 72/350 (20%), Positives = 122/350 (34%), Gaps = 33/350 (9%)

Query: 25   TATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLE 84
            TA   + ++ +E  L      L+ + ++K+   +I+EK   +A+   L  ++    +  E
Sbjct: 721  TALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEK---DAMIKVLQQRSRKEPSKTE 777

Query: 85   ELAYRRSLRVALDVLSEGSIWSQESSAGTG-------RADRSLRGKPMEHVSSPCDSNSS 137
            +L+  R  +  + + + GS     SS  TG       R D+S +G            +  
Sbjct: 778  QLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKG------------SLG 825

Query: 138  SLPRGDVLGSSRPHRRRPCVQQS-LSSSFTCEKDPECKVDHKKGLRKSENPR-GPLVLPA 195
             L  GD      P    P    + L S+ +     +C    ++G   ++     P+ +PA
Sbjct: 826  ILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPA 885

Query: 196  G-GGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAP 254
                A   +         T         A  A+     ++     T     +     AA 
Sbjct: 886  PVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAG 945

Query: 255  SLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPA 314
             +P+        A A        +    A PAP P+    P   PA  +     +  P  
Sbjct: 946  QIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQ-----ASAPAQ 1000

Query: 315  VQLEPMAAGAAPSPGPGPGP--RESVTPRSTARLGPPPSHASADATRCLP 362
             Q    A   AP+P P P P   ++  P S A  GP P   S  +  C P
Sbjct: 1001 TQAPTSAPAVAPTPAPTPTPAVAQAEVPASPA-TGPGPHRLSIPSLTCNP 1049


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 59/238 (24%), Positives = 78/238 (32%), Gaps = 18/238 (7%)

Query: 141  RGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPEC-KVDHKKGLRKSENPRGPLVLPAGGGA 199
            RG   G  R         +  S   + EKD E  + D +   R+              G 
Sbjct: 948  RGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGE 1007

Query: 200  QDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSG 259
             +ES S    K    A   G N +   S   + SS S   +     S   S +  S    
Sbjct: 1008 DEESDSS--SKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065

Query: 260  VREDDPCANAEGHDPG----LPLGSLTAPPAPEPSACSEPGECPAKK----RPRLDGSQR 311
              E+ P A      P     +P  +    P PE  A S     P ++    RP     + 
Sbjct: 1066 EEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEES 1125

Query: 312  PPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSH----ASADATRCLPCPD 365
            PP+  L P    A P   P P PR    P S   L PPP       S  A   +P P+
Sbjct: 1126 PPSAPLRPPEPPAGP---PAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPE 1180



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 19/113 (16%)

Query: 252  AAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDG-SQ 310
            A+P+ P+G  E+ P        P  PL     PPA  P+    P E P+   P L    +
Sbjct: 1113 ASPARPAGPTEESP--------PSAPLRP-PEPPAGPPAPAPRPDERPSSPIPLLPPPKK 1163

Query: 311  RPPAVQLEPMAAGAAPSPGPG-------PGPRESVTPRSTARL--GPPPSHAS 354
            R   V    +    AP P P        PGP     PR   R     P  HAS
Sbjct: 1164 RRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHAS 1216



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 36/128 (28%), Positives = 46/128 (35%), Gaps = 10/128 (7%)

Query: 274 PGLPLGSLTA---PPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGP 330
           PG P    TA   PP+       EP   P  +  R   S+ PP    EP   G    P P
Sbjct: 393 PGAPFAENTAERFPPSYTSYLPPEPSR-PTDQDYRPPASEAPPPEPPEPGGGGGGGGPSP 451

Query: 331 -GPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSIL 389
                R S  P S AR G P    + ++      P +Q    + +         S  S L
Sbjct: 452 EREEVRTSPRPASPARSGSPAPETTNESV-----PFAQHSSLDSRIEMLLKEQRSKFSFL 506

Query: 390 EEDEEDEE 397
             D E+EE
Sbjct: 507 ASDTEEEE 514



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 35/132 (26%), Positives = 48/132 (36%), Gaps = 28/132 (21%)

Query: 233 SSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPE---- 288
           +S +E++ E      G       +PSG           GH P  P      PPAP     
Sbjct: 507 ASDTEEEEENSSMVLGARDTGSEVPSG----------SGHGPCTP------PPAPANFED 550

Query: 289 --PSACSEPGECPAKKRPRLDG-SQRPPAVQLEPMAAG---AAPSPGPGPGPRESVTPRS 342
             P+   EPG    ++ P+ +G +Q  P    + M         SP P P P +   P  
Sbjct: 551 VAPTGSGEPGA--TRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPP 608

Query: 343 TARLGPPPSHAS 354
                PPP  AS
Sbjct: 609 PPPPPPPPYLAS 620



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 42/175 (24%), Positives = 53/175 (30%), Gaps = 20/175 (11%)

Query: 254  PSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPE----------------PSACSEPGE 297
            PS P+   EDDP    E  +PG P    T PP  +                 S   E  +
Sbjct: 914  PSTPAEEDEDDPEQEKEAGEPGRP---GTKPPKRDEERGKTQGKHRKSFALDSEGEEASQ 970

Query: 298  CPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADA 357
              + ++   D  +       E              G  E     S   L    S    D+
Sbjct: 971  ESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL-YADSDGENDS 1029

Query: 358  TRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEV 412
            T       S        SS  S  S+S      EDEE+EE P  L    P   EV
Sbjct: 1030 TSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREV 1084


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 65/263 (24%), Positives = 86/263 (32%), Gaps = 45/263 (17%)

Query: 140  PRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGA 199
            PR   +  SRP  R P     L S      +P   +  K+   K   P+  L        
Sbjct: 1042 PRRHAMPGSRPRSRIPV----LLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLV---- 1093

Query: 200  QDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGS----KGGSWAAPS 255
             ++   R+  +  + AS       ++AS  L+G+   ED    +  +    K G  AA  
Sbjct: 1094 MEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATR 1153

Query: 256  ----------LPSGVREDDPCANAEGHDPGL------------PLGSLTAP---PAPEPS 290
                      +P  V    P + + G  P L            P GS TA    P   P 
Sbjct: 1154 SRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAADLRPKQPPG 1213

Query: 291  ACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAP-----SPGPGPGPRESVTPRSTAR 345
                PG   A  RP    S R PA       A A+P     S    P P     P     
Sbjct: 1214 RGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPP 1273

Query: 346  LGPPPSHASADATRCLPCPDSQK 368
             G PP+ A  D T   P P   K
Sbjct: 1274 RGVPPARAQPDGT---PSPGGSK 1293


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 36/135 (26%), Positives = 53/135 (39%), Gaps = 11/135 (8%)

Query: 274 PGLPLGSL---TAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGP 330
           P LPL +    + PP P PS    P  CP+   PR     R       P    A P P P
Sbjct: 321 PQLPLNAAPPSSVPPVP-PSEALPPPACPSAPAPRRSIISR--LFGTSPATEAAPPPPEP 377

Query: 331 GPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKL-----EKECQSSEESMGSNSM 385
            P      T +S     P      +      P  D +K+     +++  S  E++G N M
Sbjct: 378 VPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPM 437

Query: 386 RSILEEDEEDEEPPR 400
            +  ++D + E+ PR
Sbjct: 438 VAGFQDDVDLEDQPR 452



 Score = 37.0 bits (84), Expect = 0.063
 Identities = 48/207 (23%), Positives = 70/207 (33%), Gaps = 53/207 (25%)

Query: 232 GSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSL---------- 281
           G+  ++ D++ D  + GG+     + +G ++D    +     P LP G +          
Sbjct: 417 GAKAAQQDSDSDGEALGGN----PMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSE 472

Query: 282 --------TAPPAPEPSACSEP----GECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPG 329
                   T  PAP P  CSEP       PA K          P     P    A P PG
Sbjct: 473 EEAEVAAPTKGPAPAPQQCSEPETKWSSIPASK----------PRRGTAPTRTAAPPWPG 522

Query: 330 -----PGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNS 384
                 GP  R S  P +    G     +S+++    P               ES GS++
Sbjct: 523 GVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDT 582

Query: 385 MR------------SILEEDEEDEEPP 399
            R             + +EDE   EPP
Sbjct: 583 QRRADDFPVRDDPSDVTDEDEGPAEPP 609


>gi|195963410 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 22/142 (15%)

Query: 283 APPA--PEPSACSEPGECP-------AKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPG 333
           APP   P+P     P   P       A    R  GS +P A    P    AA +PG  P 
Sbjct: 206 APPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 265

Query: 334 PRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSS---EESMGSNSMRSILE 390
           P  +  P +   L P     SA  T          LE+E Q +    + + +  +  ILE
Sbjct: 266 PTPTPAPAAAPALTPSSGPGSAALT----------LEEELQEAIRRAQLLPNRGIDDILE 315

Query: 391 EDEEDEEPPRVLLYHEPRSFEV 412
           +  E ++P   +    P SF+V
Sbjct: 316 DQVEPDDPLPPIPLDFPGSFDV 337


>gi|32698970 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 2 [Homo sapiens]
          Length = 312

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 22/142 (15%)

Query: 283 APPA--PEPSACSEPGECP-------AKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPG 333
           APP   P+P     P   P       A    R  GS +P A    P    AA +PG  P 
Sbjct: 103 APPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRAADTPGTAPA 162

Query: 334 PRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSS---EESMGSNSMRSILE 390
           P  +  P +   L P     SA  T          LE+E Q +    + + +  +  ILE
Sbjct: 163 PTPTPAPAAAPALTPSSGPGSAALT----------LEEELQEAIRRAQLLPNRGIDDILE 212

Query: 391 EDEEDEEPPRVLLYHEPRSFEV 412
           +  E ++P   +    P SF+V
Sbjct: 213 DQVEPDDPLPPIPLDFPGSFDV 234


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/125 (32%), Positives = 47/125 (37%), Gaps = 17/125 (13%)

Query: 274 PGLPLGSLTA-PPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGP 332
           P  P G  TA PP P   A  EP E PA   P       PP            P PGP  
Sbjct: 810 PIAPTGPPTASPPVP---AKEEPEELPAAPGPLPPPPPPPP------------PVPGPVT 854

Query: 333 GPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEED 392
            P   + P  T   G PP+    D T        ++ E+E +  EE           EE+
Sbjct: 855 LPPPQLVPEGTPGGGGPPA-LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913

Query: 393 EEDEE 397
           EEDEE
Sbjct: 914 EEDEE 918



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 30/79 (37%), Positives = 35/79 (44%), Gaps = 15/79 (18%)

Query: 274 PGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPM-AAGAAPSPGPGP 332
           P  P+G     PAP P     P E P+  R        PP     PM + G+ PS GP P
Sbjct: 637 PLQPMGPTCPTPAPVP-----PPEAPSPFRA-------PPFHPPGPMPSVGSMPSAGPMP 684

Query: 333 --GPRESVTPRSTARLGPP 349
             GP  S  P  +AR GPP
Sbjct: 685 SAGPMPSAGPVPSARPGPP 703


>gi|226371735 iroquois homeobox 3 [Homo sapiens]
          Length = 501

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 39/121 (32%), Positives = 47/121 (38%), Gaps = 30/121 (24%)

Query: 252 AAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQ- 310
           A+PSLPS     DPCA A       P  +L  P     +  +   + P +  P   GS  
Sbjct: 320 ASPSLPSPPVSLDPCAPAPA-----PASALQKPKIWSLAETATSPDNPRRSPPGAGGSPP 374

Query: 311 ----RPPAVQLEPMAAGAA------------------PSPGPGPGPRESVTPRSTARLGP 348
                P A+QL P AA AA                  P PGP PGPR  + P S     P
Sbjct: 375 GAAVAPSALQLSPAAAAAAAHRLVSAPLGKFPAWTNRPFPGPPPGPR--LHPLSLLGSAP 432

Query: 349 P 349
           P
Sbjct: 433 P 433


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 38/131 (29%), Positives = 45/131 (34%), Gaps = 19/131 (14%)

Query: 252 AAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECP-----AKKRPRL 306
           A P  P       P A A    P  P      PP P P A + P   P     A   P  
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTP----APPPPPAPVAAAAPARAPRAAAAAATAPPS 161

Query: 307 DG-------SQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTAR---LGPPPSHASAD 356
            G       +QR   +   P A  A P+  P  GPR +  P   AR   L PPP   +  
Sbjct: 162 PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221

Query: 357 ATRCLPCPDSQ 367
             +  P P  Q
Sbjct: 222 QQQQPPPPQPQ 232


>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
          Length = 1416

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/123 (30%), Positives = 48/123 (39%), Gaps = 11/123 (8%)

Query: 247  KGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGE-CPAKKRPR 305
            K G    P L  G R+      A+   P  P       PAPE  A   PG   P   RP 
Sbjct: 938  KPGRRGFPELVLGTRDTGSKGVADDVVPPGP------GPAPEAPAQEGPGSGSPRDTRPL 991

Query: 306  LDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPD 365
                  PP   LE +A   AP PGP   P  +  P S+++ G PP      A    P  D
Sbjct: 992  STQRPLPPLCSLETIAEEPAPGPGP---PPPAAVPTSSSQ-GRPPYPTGPGANVASPLED 1047

Query: 366  SQK 368
            +++
Sbjct: 1048 TEE 1050


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 62/233 (26%), Positives = 79/233 (33%), Gaps = 30/233 (12%)

Query: 189 GPLVLPAGGGAQDESGSRIHHKNWTLASKRG---GNSAQKASLCLNGSSLSEDDTERDMG 245
           G  VLP G   Q     R  +       + G   GN     SL L+     E   E    
Sbjct: 73  GHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQR 132

Query: 246 SKGGSWAAPSLPSGVREDDPCANAEGHDPGLP-----LGSLTAPPAPEPSACSEPGECPA 300
            +         PS  +   P   A G  P +P     L     PP  EP         PA
Sbjct: 133 LRSDPGPPTETPS--QRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLEPIPPPPSRPLPA 190

Query: 301 KKR------PRLDGSQRPPAV-------QLEPM-AAGAAPSPGPGPGPRESVTPRSTARL 346
             R      PR + S    AV       + EP+  A   P PGP PGP E V        
Sbjct: 191 DPRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASDRPVPGPSPGPPEPVMLPQPTSQ 250

Query: 347 GPPPSHASADATRCL----PCP-DSQKL-EKECQSSEESMGSNSMRSILEEDE 393
            P P     +A+RCL    P P D +K+  ++      S  SNS  +    D+
Sbjct: 251 PPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDD 303


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 70/301 (23%), Positives = 111/301 (36%), Gaps = 53/301 (17%)

Query: 106  SQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLG-SSRPHRRRPCVQQS---- 160
            SQ+   G  ++  S  G  +       DS   +   G + G ++R H RR    +S    
Sbjct: 1124 SQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQER 1183

Query: 161  --------LSSSFTCEKDPECKVD---HKKGLRKSENPRGPLVLPAGGGAQDESGSRIHH 209
                    L+   T +K  EC+++   HK    K +           G A DE  + +  
Sbjct: 1184 ASRPRLTILNVCNTGDKMVECQLETHNHKMVTFKFD---------LDGDAPDEIATYMVE 1234

Query: 210  KNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGS----WAAPSLPSGVREDDP 265
             ++ L ++R     Q   +      +  +DT+ D GS  G+     +   L +G      
Sbjct: 1235 HDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQS 1294

Query: 266  CANAEGHDPGL-----------PLGSLTAPPAPEPSA----CSEPGECPAKKRP---RLD 307
             ANA  +   +           P+    AP APE S      S P E      P   +L 
Sbjct: 1295 QANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLS 1354

Query: 308  GSQRPPAVQLEPMAAGAAPSPGPG--PGPRESVTPRSTARLGPPPSHASADATRCLPCPD 365
              ++P  +  + + + A PS  PG  P P    +P  TA     P   +A AT  +P P 
Sbjct: 1355 SKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTAL----PQDGAAPATSTMPEPA 1410

Query: 366  S 366
            S
Sbjct: 1411 S 1411



 Score = 34.7 bits (78), Expect = 0.31
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)

Query: 284 PPAPEPSAC-SEPGE--CPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRE 336
           P AP P+A  ++PG    PA   P   G+Q P     +P+AA    +P P  GPRE
Sbjct: 93  PAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGP---DPIAAAVETAPAPDGGPRE 145



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 22/107 (20%)

Query: 255 SLPSGVREDDPCANAEGHDPGLPLGSLTAPPA--------PEPSACSEPG-ECPAKKRPR 305
           SLPS      P A      PGLP+GS+ AP          P+P+    P    P+   P 
Sbjct: 665 SLPSLGAYQQPTAA-----PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT 719

Query: 306 LDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSH 352
             G   PP  Q  P+   A P+P P     + + P+    L P P H
Sbjct: 720 GPGQPAPPGQQPPPL---AQPTPLP-----QVLAPQPVVPLQPVPPH 758


>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
           sapiens]
          Length = 402

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 39/150 (26%), Positives = 53/150 (35%), Gaps = 5/150 (3%)

Query: 242 RDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPE-PSACSEPGECPA 300
           R  G++ G    P  P       P        P  P      P +PE P   + P E   
Sbjct: 11  RCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVPAAPRYLPPLPASPETPERAAGPSEPLG 70

Query: 301 KKRPRLDGSQR--PPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADAT 358
           +  PR  G+    PP + L+P     A +   G GPR  +   + A+ GP  S A A   
Sbjct: 71  EVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRR-LPEAAAAKGGPGESEAGAGGE 129

Query: 359 R-CLPCPDSQKLEKECQSSEESMGSNSMRS 387
           R      D  +    C S   S G    R+
Sbjct: 130 RERRGAGDQPETRSVCSSRSSSSGGGDQRA 159


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,660,624
Number of Sequences: 37866
Number of extensions: 1800709
Number of successful extensions: 12257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 812
Number of HSP's that attempted gapping in prelim test: 9398
Number of HSP's gapped (non-prelim): 2953
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.