Guide to the Human Genome
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Search of human proteins with 31563537

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
         (1538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]      3007   0.0  
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]     2782   0.0  
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]     2775   0.0  
gi|57863301 CLIP-associating protein 2 [Homo sapiens]                1982   0.0  
gi|161016767 mucin 21 [Homo sapiens]                                   64   1e-09
gi|93102424 hypothetical protein LOC23116 [Homo sapiens]               62   4e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        59   4e-08
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             56   2e-07
gi|57222563 colonic and hepatic tumor over-expressed protein iso...    54   9e-07
gi|57164942 colonic and hepatic tumor over-expressed protein iso...    54   9e-07
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             54   2e-06
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          53   3e-06
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    52   3e-06
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    52   3e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         52   6e-06
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    51   8e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        50   1e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    50   1e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  49   3e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    49   4e-05
gi|42518068 trans-golgi network protein 2 [Homo sapiens]               49   4e-05
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     47   1e-04
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    47   1e-04
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    47   1e-04
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           47   1e-04
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     46   2e-04
gi|50083281 KIAA1853 protein [Homo sapiens]                            46   2e-04
gi|60097902 filaggrin [Homo sapiens]                                   46   3e-04
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    46   3e-04
gi|51173722 bromodomain and PHD finger-containing protein 1 isof...    46   3e-04

>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
          Length = 1538

 Score = 3007 bits (7795), Expect = 0.0
 Identities = 1538/1538 (100%), Positives = 1538/1538 (100%)

Query: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60
            MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN
Sbjct: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60

Query: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120
            SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD
Sbjct: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120

Query: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180
            QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN
Sbjct: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180

Query: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
            SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN
Sbjct: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240

Query: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300
            FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE
Sbjct: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300

Query: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360
            DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD
Sbjct: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360

Query: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420
            NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN
Sbjct: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420

Query: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480
            SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL
Sbjct: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480

Query: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540
            ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL
Sbjct: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540

Query: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600
            KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS
Sbjct: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600

Query: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR 660
            DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR
Sbjct: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR 660

Query: 661  GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720
            GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI
Sbjct: 661  GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720

Query: 721  PRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQ 780
            PRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQ
Sbjct: 721  PRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQ 780

Query: 781  PGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSY 840
            PGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSY
Sbjct: 781  PGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSY 840

Query: 841  GSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEI 900
            GSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEI
Sbjct: 841  GSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEI 900

Query: 901  FTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQ 960
            FTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQ
Sbjct: 901  FTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQ 960

Query: 961  KALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSET 1020
            KALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSET
Sbjct: 961  KALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSET 1020

Query: 1021 RLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNH 1080
            RLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNH
Sbjct: 1021 RLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNH 1080

Query: 1081 LKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPP 1140
            LKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPP
Sbjct: 1081 LKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPP 1140

Query: 1141 PFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDL 1200
            PFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDL
Sbjct: 1141 PFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDL 1200

Query: 1201 NEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPR 1260
            NEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPR
Sbjct: 1201 NEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPR 1260

Query: 1261 ARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEE 1320
            ARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEE
Sbjct: 1261 ARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEE 1320

Query: 1321 RKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPAR 1380
            RKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPAR
Sbjct: 1321 RKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQPAR 1380

Query: 1381 FKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINL 1440
            FKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINL
Sbjct: 1381 FKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINL 1440

Query: 1441 AAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLK 1500
            AAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLK
Sbjct: 1441 AAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGEDLK 1500

Query: 1501 PHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1538
            PHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
Sbjct: 1501 PHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1538


>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
          Length = 1471

 Score = 2782 bits (7212), Expect = 0.0
 Identities = 1457/1546 (94%), Positives = 1458/1546 (94%), Gaps = 83/1546 (5%)

Query: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60
            MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN
Sbjct: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60

Query: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120
            SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD
Sbjct: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120

Query: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180
            QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN
Sbjct: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180

Query: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
            SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN
Sbjct: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240

Query: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300
            FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE
Sbjct: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300

Query: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360
            DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD
Sbjct: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360

Query: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420
            NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN
Sbjct: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420

Query: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480
            SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL
Sbjct: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480

Query: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540
            ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL
Sbjct: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540

Query: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600
            KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS
Sbjct: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600

Query: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR 660
            DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR
Sbjct: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNR 660

Query: 661  GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720
            GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI
Sbjct: 661  GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720

Query: 721  PRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQ 780
            PRSQGCS                                  R+TSP R    LDRFGLGQ
Sbjct: 721  PRSQGCS----------------------------------RETSPNR--IGLDRFGLGQ 744

Query: 781  PGRIPGSVNAMRVLSTSTDLEAAVADAL--------KKPVRRRYEPYGMYSDDDANSDAS 832
            PGRIPGSVNAMRVLSTSTDLEAAVADAL        KKPVRRRYEPYGMYSDDDANSDAS
Sbjct: 745  PGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSDDDANSDAS 804

Query: 833  SVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRV 892
            SVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRV
Sbjct: 805  SVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRV 864

Query: 893  ELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLL 952
            ELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLL
Sbjct: 865  ELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLL 924

Query: 953  GSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPT 1012
            GSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPT
Sbjct: 925  GSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPT 984

Query: 1013 DFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDG 1072
            DFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDG
Sbjct: 985  DFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDG 1044

Query: 1073 ATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSA 1132
            ATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNC               
Sbjct: 1045 ATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNC--------------- 1089

Query: 1133 DGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKF 1192
                                SH  L    SPSMLDYDTENLNSEEIYSSLRGVTEAIEKF
Sbjct: 1090 --------------------SHGGL----SPSMLDYDTENLNSEEIYSSLRGVTEAIEKF 1125

Query: 1193 SFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQP 1252
            SFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQP
Sbjct: 1126 SFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQP 1185

Query: 1253 PRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELS 1312
            PRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELS
Sbjct: 1186 PRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELS 1245

Query: 1313 NHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLRE 1372
            NHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLRE
Sbjct: 1246 NHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLRE 1305

Query: 1373 ILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQ 1432
            ILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQ
Sbjct: 1306 ILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQ 1365

Query: 1433 TADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIY 1492
            TADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIY
Sbjct: 1366 TADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIY 1425

Query: 1493 SVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1538
            SVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
Sbjct: 1426 SVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1471


>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
          Length = 1479

 Score = 2775 bits (7193), Expect = 0.0
 Identities = 1457/1554 (93%), Positives = 1458/1554 (93%), Gaps = 91/1554 (5%)

Query: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60
            MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN
Sbjct: 1    MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWVN 60

Query: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120
            SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD
Sbjct: 61   SSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMD 120

Query: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180
            QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN
Sbjct: 121  QAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPN 180

Query: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
            SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN
Sbjct: 181  SQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240

Query: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300
            FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE
Sbjct: 241  FDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEE 300

Query: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360
            DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD
Sbjct: 301  DFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAAEYD 360

Query: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420
            NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN
Sbjct: 361  NFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNLIPN 420

Query: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480
            SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL
Sbjct: 421  SAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL 480

Query: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540
            ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL
Sbjct: 481  ERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHL 540

Query: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600
            KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS
Sbjct: 541  KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600

Query: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASL--------GRIRTRRQSSGSATN 652
            DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASL        GRIRTRRQSSGSATN
Sbjct: 601  DIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLDGTTTKAEGRIRTRRQSSGSATN 660

Query: 653  VASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 712
            VASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP
Sbjct: 661  VASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 720

Query: 713  SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
            SSEKRSKIPRSQGCS                                  R+TSP R    
Sbjct: 721  SSEKRSKIPRSQGCS----------------------------------RETSPNR--IG 744

Query: 773  LDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADAL--------KKPVRRRYEPYGMYSD 824
            LDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADAL        KKPVRRRYEPYGMYSD
Sbjct: 745  LDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALLLGDSRSKKKPVRRRYEPYGMYSD 804

Query: 825  DDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLK 884
            DDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLK
Sbjct: 805  DDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLGLQNLLK 864

Query: 885  SQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLL 944
            SQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLL
Sbjct: 865  SQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFVLLTQLL 924

Query: 945  KKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIES 1004
            KKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIES
Sbjct: 925  KKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIES 984

Query: 1005 LARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGA 1064
            LARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGA
Sbjct: 985  LARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGA 1044

Query: 1065 LPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSP 1124
            LPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNC       
Sbjct: 1045 LPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNC------- 1097

Query: 1125 SRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRG 1184
                                        SH  L    SPSMLDYDTENLNSEEIYSSLRG
Sbjct: 1098 ----------------------------SHGGL----SPSMLDYDTENLNSEEIYSSLRG 1125

Query: 1185 VTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNK 1244
            VTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNK
Sbjct: 1126 VTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNK 1185

Query: 1245 TSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLV 1304
            TSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLV
Sbjct: 1186 TSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLV 1245

Query: 1305 ADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRA 1364
            ADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRA
Sbjct: 1246 ADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRA 1305

Query: 1365 LALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCI 1424
            LALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCI
Sbjct: 1306 LALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCI 1365

Query: 1425 KVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKAS 1484
            KVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKAS
Sbjct: 1366 KVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKAS 1425

Query: 1485 VFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1538
            VFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
Sbjct: 1426 VFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS 1479


>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
          Length = 1506

 Score = 1982 bits (5134), Expect = 0.0
 Identities = 1057/1562 (67%), Positives = 1232/1562 (78%), Gaps = 80/1562 (5%)

Query: 1    MEPR-MESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATSWV 59
            MEPR ME   AQV QKDVG RLQVGQEL+ Y       +DLE D   L K VD L T WV
Sbjct: 1    MEPRSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDAL-TGWV 59

Query: 60   NSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIM 119
             SSNY+V L+G++ILSA V RL  RFK+ +  V+ +LIDR+GDAKD VR++ QTL+LK+M
Sbjct: 60   GSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLILKLM 119

Query: 120  DQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDP 179
            DQ A P Y+W+++  GFKHKNFR+REG+CLCLI TLN  GAQ L +SK++PH+C L GD 
Sbjct: 120  DQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILFGDS 179

Query: 180  NSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNMIQSA-ND 238
            NSQVRDAAI ++VEIYRHVGE+VR DL K+G+P +RL +IF KFDEVQ SG MI S   D
Sbjct: 180  NSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSSGGMILSVCKD 239

Query: 239  KNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKEG-AGAV 297
            K+FDDE+SVDGNRPSSA+S      P +  N    + R+ GS+       A+KEG AGAV
Sbjct: 240  KSFDDEESVDGNRPSSAASAFKVPAPKTSGNPA-NSARKPGSAGGPKVGGASKEGGAGAV 298

Query: 298  DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKHDWEQRVNALKKIRSLLLAGAA 357
            DE+DFIKAF DVP +QIYSSR+LEE++NKIREILSDDKHDW+QR NALKKIRSLL+AGAA
Sbjct: 299  DEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAA 358

Query: 358  EYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAIMPTIFNL 417
            +YD FFQHLRLLDGA KLSAKDLRSQVVREACIT+ HLS+VLGNKFDHGAEAI+PT+FNL
Sbjct: 359  QYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDHGAEAIVPTLFNL 418

Query: 418  IPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQT 477
            +PNSAK+MATSG  A+R IIRHTH+PRLIP+ITSNCTSKSV VRRR FEFLDLLLQEWQT
Sbjct: 419  VPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFEFLDLLLQEWQT 478

Query: 478  HSLERHISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQ 537
            HSLERH +VL ETIKKGIHDAD+EAR+EARK Y G  +HF  EAE LY++LE SYQK+LQ
Sbjct: 479  HSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYNSLEPSYQKSLQ 538

Query: 538  SHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTT--SRASTVSTKSVSTTGSL 595
            ++LK+S S+ SLPQSDRSSSSSQESLNRP S+K S    +T   R S  S+K+ S  GSL
Sbjct: 539  TYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAGSSKASSLPGSL 598

Query: 596  QRSRSDIDVNAAASAKSK-VSSSSGTTPFSSAAALPPGSYASL--------------GRI 640
            QRSRSDIDVNAAA AK+   +  S  +    A AL  GSYASL              GR+
Sbjct: 599  QRSRSDIDVNAAAGAKAHHAAGQSVRSGRLGAGALNAGSYASLEDTSDKLDGTASEDGRV 658

Query: 641  RTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGS-GYGG 699
            R +  +  +    A   D+RGRSR K+VSQSQ          GSRS SPG++L +     
Sbjct: 659  RAKLSAPLAGMGNAKA-DSRGRSRTKMVSQSQ---------PGSRSGSPGRVLTTTALST 708

Query: 700  LTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRE 759
            ++ G  R    + S++KRSKIPRSQGCSRE SP+R+ +ARSSRIPRPS+SQGCSR+ SRE
Sbjct: 709  VSSGVQRVLVNSASAQKRSKIPRSQGCSREASPSRLSVARSSRIPRPSVSQGCSREASRE 768

Query: 760  SSRDTSPARGFPPLDR-FGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEP 818
            SSRDTSP R F PL   +G+ Q  R+  SV+AMRVL+T +D+E AVADALKKP RRRYE 
Sbjct: 769  SSRDTSPVRSFQPLGPGYGISQSSRLSSSVSAMRVLNTGSDVEEAVADALKKPARRRYES 828

Query: 819  YGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLLG 878
            YGM+SDDDANSDASS CSERSY SRNG IP Y+RQTEDVAEVLN CASSNWSERKEGLLG
Sbjct: 829  YGMHSDDDANSDASSACSERSYSSRNGSIPTYMRQTEDVAEVLNRCASSNWSERKEGLLG 888

Query: 879  LQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFIIIHKDDLQDWLFV 938
            LQNLLK+QRTLSRVELKRLCEIFTRMFADPH KRVFSMFLETLVDFI +HKDDLQDWLFV
Sbjct: 889  LQNLLKNQRTLSRVELKRLCEIFTRMFADPHGKRVFSMFLETLVDFIQVHKDDLQDWLFV 948

Query: 939  LLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAI 998
            LLTQLLKKMGADLLGSVQAKVQKALDVTR+SFP D QFNILMRF VDQTQTP+LKVKVAI
Sbjct: 949  LLTQLLKKMGADLLGSVQAKVQKALDVTRESFPNDLQFNILMRFTVDQTQTPSLKVKVAI 1008

Query: 999  LKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQIVLISLFELNTPEF 1058
            LKYIE+LA+QMDP DF+NSSETRLAVSR+ITWTTEPKSSDVRKAAQ VLISLFELNTPEF
Sbjct: 1009 LKYIETLAKQMDPGDFINSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEF 1068

Query: 1059 TMLLGALPKTFQDGATKLLHNHLKNSSNTSVGSPSNTIGRTPSRHTSSRTSPLTSPTNCS 1118
            TMLLGALPKTFQDGATKLLHNHL+N+ N +  S  + + R   R  ++ +SPLTSPTN S
Sbjct: 1069 TMLLGALPKTFQDGATKLLHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTNTS 1128

Query: 1119 HGGLSPSRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRSYSPSMLDYDTENLNSEEI 1178
                                                   + + SPS  DYDTEN+NSE+I
Sbjct: 1129 ---------------------------------------QNTLSPSAFDYDTENMNSEDI 1149

Query: 1179 YSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKEC-DIVSRDGGAASPATEGRGGSEVEGG 1237
            YSSLRGVTEAI+ FSFRSQED+NEP+KRD KK+  D +    G + P     GG   +  
Sbjct: 1150 YSSLRGVTEAIQNFSFRSQEDMNEPLKRDSKKDDGDSMCGGPGMSDPRA---GGDATDSS 1206

Query: 1238 RTALDNKTSLLNTQPPRAFPGPRARDYNPYPYSDAINTYDKTALKEAVFDDDMEQLRD-V 1296
            +TALDNK SLL++ P  +   PR+RDYNPY YSD+I+ ++K+ALKEA+FDDD +Q  D +
Sbjct: 1207 QTALDNKASLLHSMPTHS--SPRSRDYNPYNYSDSISPFNKSALKEAMFDDDADQFPDDL 1264

Query: 1297 PIDHSDLVADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLG 1356
             +DHSDLVA+LLKELSNHNERVEERK AL EL+K+T+E+S  VW+EHFKTILLLLLETLG
Sbjct: 1265 SLDHSDLVAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLG 1324

Query: 1357 DKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLAS 1416
            DK+ +IRALAL+VLREILR+QPARFKNYAELT+MKTLEAHKD HKEVVR+AEEAAS LA+
Sbjct: 1325 DKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAEEAASVLAT 1384

Query: 1417 SIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNT 1476
            SI PEQCIKVLCPIIQTADYPINLAAIKMQTKV+ER++KE+L  LL +I+PGL+QGYDN+
Sbjct: 1385 SISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGLIQGYDNS 1444

Query: 1477 ESSVRKASVFCLVAIYSVIGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVST 1536
            ESSVRKA VFCLVA+++VIG++LKPHL+QLTGSKMKLLNLYIKRAQT +  +  ++DVS 
Sbjct: 1445 ESSVRKACVFCLVAVHAVIGDELKPHLSQLTGSKMKLLNLYIKRAQTGSGGADPTTDVSG 1504

Query: 1537 HS 1538
             S
Sbjct: 1505 QS 1506


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 62/254 (24%), Positives = 107/254 (42%), Gaps = 20/254 (7%)

Query: 529 ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKS 588
           ESS   +  S   NS+S      +  +++S   + +   S   +   STTS  ++ +T S
Sbjct: 109 ESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNS 168

Query: 589 VSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSG 648
            S+T S   S +    ++  S+++  +++S ++  SS A     S A+    RT    +G
Sbjct: 169 ESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGA-----STATNSESRTTSNGAG 223

Query: 649 SATNVASTPDNRGRSRAKVVSQSQRSRSANPA----------GAGSRSSSPGKLLGSGYG 698
           +ATN  S+  + G S A     S  S  A  A          GAG+ ++S    + SG  
Sbjct: 224 TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283

Query: 699 GLTGGSSRGP-----PVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS 753
            +T   S  P       T S    +    +   + ++S    G + ++     + S G S
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGAS 343

Query: 754 RDTSRESSRDTSPA 767
             T+ ESS  +S A
Sbjct: 344 TATNSESSTTSSGA 357



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 70/289 (24%), Positives = 119/289 (41%), Gaps = 13/289 (4%)

Query: 529 ESSYQKALQSHLKNSDS-IVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTK 587
           ESS   +  S   NS+S   S   S  ++S S+ + N   +A  S + +T+S AST +  
Sbjct: 184 ESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNS 243

Query: 588 SVST----TGSLQRSRSDIDVNAAASAKSKVSS--SSGTTPFSSAAALPPGSYASLGRIR 641
             ST     G+   S S    + A +A +  SS  SSG +  +++ +  P S A+     
Sbjct: 244 ESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNS 303

Query: 642 TRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLT 701
               +S  A    ++  +   S A   + S+ S +++ A   + S S     G+     +
Sbjct: 304 ESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNS 363

Query: 702 GGS--SRGPPVTPSSEKRS-KIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSR 758
           G S  S G     +SE  +     S   + E+S    G + ++     ++S G S  T+ 
Sbjct: 364 GSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNS 423

Query: 759 ESSRDTSPARGFPPLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADA 807
           ESS  +S A         G        G+     + +TS     AV++A
Sbjct: 424 ESSTTSSGAN---TATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEA 469



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 50/229 (21%), Positives = 96/229 (41%), Gaps = 4/229 (1%)

Query: 542 NSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD 601
           N  SIV+  +   +SS    + N   S   S     T+  S+ ++   ST  + + S   
Sbjct: 70  NGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPS 129

Query: 602 IDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRG 661
              + A ++ S  +SS  +T  +S ++      ++     +   SSG++T   ++  +  
Sbjct: 130 SGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGAST-ATNSESSTV 188

Query: 662 RSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP 721
            SRA   + S+ S +++ A   + S S     G+G    +  S+     + ++   S  P
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248

Query: 722 RS---QGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPA 767
            S      + E+S    G   ++     ++S G S  T+ ESS  +S A
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGA 297



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 56/249 (22%), Positives = 101/249 (40%), Gaps = 11/249 (4%)

Query: 527 TLESSYQKALQSHLKNSDSIVSLPQSDRSS--SSSQESLNRPLSAKRSPTGSTTSRASTV 584
           T  S    A  S    + S  S   +  SS  SS   +     S+  S   ST + + + 
Sbjct: 142 TTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESS 201

Query: 585 STKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRR 644
           +T S ++T +   SR+  +    A+     ++SSG +  +++ +  P S A      T  
Sbjct: 202 TTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTA---TNS 258

Query: 645 QSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANP-AGAGSRSSSPGKLLGSGYGGLTGG 703
           +SS +++   +  ++   + +  +S    S S+ P +GA + ++S      SG    T  
Sbjct: 259 ESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNS 318

Query: 704 -----SSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSR 758
                SS     T S    +    S   + E+S    G + ++     + S G S  T+ 
Sbjct: 319 DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNS 378

Query: 759 ESSRDTSPA 767
           ESS  +S A
Sbjct: 379 ESSTVSSGA 387


>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
          Length = 1720

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 24/227 (10%)

Query: 14  QKDVGKRLQVGQELIDYFSDKQKSADLEHDQTMLDKLVD--GLATSWVNSSNYKVVLLGM 71
           Q+D   R Q  +EL      KQ         T    LV    L  + ++ SN+KVV   +
Sbjct: 362 QEDYKNRTQAVEEL------KQVLGKFNPSSTPHSSLVGFISLLYNLLDDSNFKVVHGTL 415

Query: 72  DILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAANPQYVWDR 131
           ++L  LV RL ++ +  +G V+ + +  L D K  ++++   + LK+M +   PQ V   
Sbjct: 416 EVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKE-VGPQQVLCL 474

Query: 132 MLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNSQVRDAAINSL 191
           +L   KHK+ R RE +    I +L    ++   L K+   +   L D   +VR AA+ + 
Sbjct: 475 LLEHLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAF 534

Query: 192 VEIYRHVGERVRADLSKKGLPQSRLNVIFTKFD--EVQKSGNMIQSA 236
             +   +G               + +++F   D  E+Q +G+ + +A
Sbjct: 535 AVLASSMG-------------SGKTSILFKAVDTVELQDNGDGVMNA 568


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 72/261 (27%), Positives = 104/261 (39%), Gaps = 38/261 (14%)

Query: 538 SHLKNSDSIVSLPQSD---RSSSSSQESLNRPLSAKRSPT----GSTTSRASTVSTKSVS 590
           SH + S S  S  +S    +   S   + +R +   RSP     G + SR  T    S S
Sbjct: 449 SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508

Query: 591 TTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSA 650
            +   +RSRS     A    +S+     G    S +   P  S +   + R R +S+   
Sbjct: 509 RSPQWRRSRS-----AQRWGRSRSPQRRGR---SRSPQRPGWSRSRNTQRRGRSRSARRG 560

Query: 651 TNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRG--- 707
            + + +P  RGRSR++  ++  RSRS  PA   SRS +P +           G SR    
Sbjct: 561 RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTP 620

Query: 708 ------------------PPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMS 749
                              P   S   RS+ P  +G SR  +P R G +R SR P     
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSR-SRTPARRSG 679

Query: 750 QGCSRDTSRES-SRDTSPARG 769
           +  SR  +R   SR  +P RG
Sbjct: 680 RSRSRTPARRGRSRSRTPRRG 700



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/248 (29%), Positives = 105/248 (42%), Gaps = 36/248 (14%)

Query: 537  QSHLKNSDSIVSLPQSDRSSS---SSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTG 593
            +S   +S    +LPQ+ R  S   SS E  N+ L+ +R  +GS +S    V  K+V+ T 
Sbjct: 1477 RSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS----VDQKTVARTP 1532

Query: 594  SLQRSRS----DIDVNAAASAKSKVSSSSGTTPFSSAAALPP-------GS---YASLGR 639
              QRSRS    ++DV  +AS + +  S S ++P S A    P       GS     S  R
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQER--SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590

Query: 640  IRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSAN-----PAGAGSRSSSPGKLLG 694
            +  RR  SGS+  V   P  R   RA+  S S     A      P  + S SSS G+   
Sbjct: 1591 LSPRRSRSGSSPEVKDKP--RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648

Query: 695  SGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIG------LARSSRIPRPSM 748
                  T  S   PP + ++ + S+          T P R        L R +R+ R S 
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR 1708

Query: 749  SQGCSRDT 756
            S   S +T
Sbjct: 1709 SASSSPET 1716



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 58/212 (27%), Positives = 91/212 (42%), Gaps = 9/212 (4%)

Query: 562 SLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTT 621
           S  R  S  RSP     SR+ T + +  S + +  R RS         ++S+  +  G +
Sbjct: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615

Query: 622 PFSSAAALPPGSYASLGR-IRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPA 680
              + A     + + + R  R+R  +  S  + + TP  RGRSR++  ++  RSRS  PA
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA 675

Query: 681 --GAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETS----PNR 734
                SRS +P +   S       G SR   +       S+ P+ +G S  +S     +R
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735

Query: 735 IGLARSSRIPRPSMSQGCSRDTSRESSRDTSP 766
               RS     P M +  SR +SR S   +SP
Sbjct: 736 TSQRRSRSNSSPEMKK--SRISSRRSRSLSSP 765



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 66/234 (28%), Positives = 103/234 (44%), Gaps = 30/234 (12%)

Query: 550  PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVS------TKSVSTTGSLQRSRSDID 603
            P   RSS SS E   +   ++RS + S++    + +      + SVS+    ++SRS   
Sbjct: 1685 PPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR 1744

Query: 604  VNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIR------TRRQSSGSATNVASTP 657
              +A+S ++K +S  G +P    +  P G   S  R R      TRR+    ++   S  
Sbjct: 1745 RRSASSPRTKTTSRRGRSP----SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800

Query: 658  DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGG-LTGGSSRGPPVTPSSEK 716
              R RSR++V  + +        G+G  S SP +   S        G SR P   P+S K
Sbjct: 1801 RQRSRSRSRVTRRRR-------GGSGYHSRSPARQESSRTSSRRRRGRSRTP---PTSRK 1850

Query: 717  RSKIPRSQGCSRETSPNRIGLA--RSSRIPRPSMSQGCSRDTSRESSRDTSPAR 768
            RS+  R+     + S +R   A  R SR   P +S+  SR  +   SR  S +R
Sbjct: 1851 RSR-SRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 65/224 (29%), Positives = 95/224 (42%), Gaps = 29/224 (12%)

Query: 554  RSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSK 613
            RSSSSS  S           + S++S +S+ S+ S S + S     S + V    + K +
Sbjct: 2531 RSSSSSSSS-----------SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK-R 2578

Query: 614  VSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQR 673
            V S +     +     PP    +    R RR SS S+++ +S+  +   S +   S S  
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAK---RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635

Query: 674  SRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR----SQGCSRE 729
            S S++ + + S S SP K    G   L   +S  P   P  E+RS+ PR    S   SR 
Sbjct: 2636 SSSSSSSSSSSSSPSPAK---PGPQALPKPAS--PKKPPPGERRSRSPRKPIDSLRDSRS 2690

Query: 730  TSPNRIGLARSSRIPRP-----SMSQGCSRDTSRESSRDTSPAR 768
             S + +   R S  P P     S S+  SR   R  SR  S  R
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 60/231 (25%), Positives = 91/231 (39%), Gaps = 27/231 (11%)

Query: 550 PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVS--TTGSLQRSRSDIDVNAA 607
           P  +RSS+  +     PL A+R          + +S + V+  +  S  R RS       
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP----PK 407

Query: 608 ASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKV 667
           +  K   SSSS ++P S          +S         + GS   ++S+P ++ RS  + 
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGR- 466

Query: 668 VSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR----- 722
            ++  +S S  P+    RS SP             G SR    T     RS+ P+     
Sbjct: 467 -AKRDKSHSHTPSRRMGRSRSPAT--------AKRGRSRSRTPTKRGHSRSRSPQWRRSR 517

Query: 723 -SQGCSRETSPNRIGLARSSRIP-----RPSMSQGCSRDTSRESSRDTSPA 767
            +Q   R  SP R G +RS + P     R +  +G SR   R  S   SPA
Sbjct: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPA 568



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 65/246 (26%), Positives = 92/246 (37%), Gaps = 59/246 (23%)

Query: 554 RSSSSSQESLNRPLSAKRSPTGSTT----SRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
           RS SSS+       S +RS + S+     SR S+  ++S+S+  S  +SR  + +  + S
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR--LSLRRSLS 780

Query: 610 AKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVAS--TPDNRGRSRAKV 667
             S        TP                    RR  SGS+   A   TP  R RS +  
Sbjct: 781 GSSPCPKQKSQTP-------------------PRRSRSGSSQPKAKSRTPPRRSRSSS-- 819

Query: 668 VSQSQRSRSANPAGAGSRSSSPGKLLGSG----YGGLTGGSSRGPPVT----------PS 713
            S   + +S  P+     SSSP   + SG     G +T   +    VT          P 
Sbjct: 820 -SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878

Query: 714 SEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS-----------RDTSRESSR 762
            E +S+ P    CS  + P      +SS  PR S S+  S           R  S   S 
Sbjct: 879 PELKSRTPSRHSCSGSSPPR----VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934

Query: 763 DTSPAR 768
             SP+R
Sbjct: 935 SPSPSR 940



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 66/249 (26%), Positives = 104/249 (41%), Gaps = 19/249 (7%)

Query: 529 ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKS 588
           +SS +K    H   S+S     +S  +  S ++S ++     RS T +  SR +  ST +
Sbjct: 211 KSSKKK---KHRSESESKKRKHRSP-TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266

Query: 589 VSTTGS-LQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGS--YASLGRIRTRRQ 645
            S + S   RSRS      +A+AK+  ++ +G +P  ++     G   ++  G   T+R 
Sbjct: 267 DSASSSDTSRSRS-----RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321

Query: 646 SS-GSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGS 704
           SS  +AT   S+P        K  S ++ S S   +  G    +P  LL   +GG     
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381

Query: 705 SRGP----PVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRES 760
           +  P    PV P SE      RS   S E  P     +  S  P P  ++     +S   
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ--SSSSESSPPSPQPTKVSRHASSSPE 439

Query: 761 SRDTSPARG 769
           S   +PA G
Sbjct: 440 SPKPAPAPG 448



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 62/227 (27%), Positives = 87/227 (38%), Gaps = 16/227 (7%)

Query: 553  DRSSSSSQESLNRPLSAKRSPT------GSTTSRASTVSTKSVSTTGSLQRSRSDIDVNA 606
            DRS SS   S  R  S  RS        GS     S    +S  T+   +R RS     +
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848

Query: 607  AASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAK 666
               ++S+ S +      S A+        S   + +RR+S    + V+     R RSR  
Sbjct: 1849 RKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR---RRSRSRTS 1905

Query: 667  VVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGL----TGGSSRGPPVTPSSEKRSKIPR 722
            V  +  RSR++  +   SRS +P                   SR PPVT    +    P 
Sbjct: 1906 VTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965

Query: 723  SQGCSR-ETSP--NRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSP 766
            ++  SR  TSP   R   +R+S + R       S  T R S   TSP
Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSP 2012



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 61/240 (25%), Positives = 89/240 (37%), Gaps = 45/240 (18%)

Query: 530  SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAK------------------- 570
            SS   +  S   +S S  S   S  SSSS  E  + P+  +                   
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592

Query: 571  -RSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAAL 629
             R P  +   R    S+ S S++ S   S S    ++++S+ S  SSSS ++  SS +  
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652

Query: 630  PPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSP 689
             PG  A       ++   G         + R RS  K +   + SRS + +    R  SP
Sbjct: 2653 KPGPQALPKPASPKKPPPG---------ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703

Query: 690  -----GKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIP 744
                  +   S   G   G  RG   +PS ++R          RET   R    RSSR P
Sbjct: 2704 QPSPRDQQSSSSERGSRRG-QRGDSRSPSHKRR----------RETPSPRPMRHRSSRSP 2752



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 58/209 (27%), Positives = 77/209 (36%), Gaps = 29/209 (13%)

Query: 550  PQSDRSSSSSQESLNRPLSAKR-SPTGSTTSRAST---VSTKSVSTTGSLQRSRSDIDVN 605
            P + R S S    + R  S  R SP     SR+ T      +S S T  + R RS     
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRA 665
             A   +S+  S +   P   + +  P +     R RT R + G  +   S P  R RS +
Sbjct: 2024 PAIRRRSR--SRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS 2081

Query: 666  KVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQ- 724
               S S RSRSA P    + S                  SR PPV  +S + S   R   
Sbjct: 2082 G--SSSDRSRSATPPATRNHS-----------------GSRTPPVALNSSRMSCFSRPSM 2122

Query: 725  ---GCSRETSPNRIGLARSSRIPRPSMSQ 750
                  R  SP  +    SSR P   + Q
Sbjct: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQ 2151



 Score = 38.9 bits (89), Expect = 0.039
 Identities = 74/320 (23%), Positives = 113/320 (35%), Gaps = 48/320 (15%)

Query: 533  QKALQSHLKNSDSIVSLPQSDRSSSSS--QESLNRPLSAKRSPTGS---TTSRASTVSTK 587
            + A  S  +  D     P  DR  SS   +++L  P   +RS  GS   T  + S + T 
Sbjct: 1174 EDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTP-PRERSGAGSSPETKEQNSALPTS 1232

Query: 588  SVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSS 647
            S          +S+       S  S       T+ F S+  +      SL   +++ Q+S
Sbjct: 1233 SQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQAS 1292

Query: 648  GSATNVASTPDNRG----RSRAKVVSQSQRSRSANPAGAGSRSSSP-GKLLGSGYGGLTG 702
              A  V S   + G        K +S S    ++  +    R+S P G  + +G+     
Sbjct: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352

Query: 703  GSSRGP-----PVTPSSEKRSKIPRSQG-CSRETSPNRIGLA------------------ 738
                GP        PS + + +  RS G  S E SP+ +  A                  
Sbjct: 1353 EDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPR 1412

Query: 739  -----RSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQPGR--IPGSVNAM 791
                 RSS    P M  G  R  SR S   +SP        R G G P R  + GS   M
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL------RDGSGTPSRHSLSGSSPGM 1466

Query: 792  RVLSTSTDLEAAVADALKKP 811
            + +  +     +  D+  +P
Sbjct: 1467 KDIPRTPSRGRSECDSSPEP 1486



 Score = 38.5 bits (88), Expect = 0.051
 Identities = 64/271 (23%), Positives = 90/271 (33%), Gaps = 26/271 (9%)

Query: 550  PQSDRSSSSSQESLNRPLSA--KRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAA 607
            P++   S SS E       A  +RS +GS++         S ST  S +           
Sbjct: 1612 PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG 1671

Query: 608  ASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKV 667
            + +  +  + S T P                    RR+SS S+  +        RSR+  
Sbjct: 1672 SRSSPEPKTKSRTPP--------------------RRRSSRSSPELTRKARLSRRSRSAS 1711

Query: 668  VSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCS 727
             S   RSR+          SSP     S        +S     T S   RS  P+ +G  
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQ 1771

Query: 728  RETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQPGRIPGS 787
            R  S +R      +R  R     G S+ TSR   R  S +R      R G G   R P  
Sbjct: 1772 RSRSRSR---REKTRTTRRRDRSGSSQSTSRRRQRSRSRSR-VTRRRRGGSGYHSRSPAR 1827

Query: 788  VNAMRVLSTSTDLEAAVADALKKPVRRRYEP 818
              + R  S      +      +K  R R  P
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 40/150 (26%), Positives = 60/150 (40%), Gaps = 6/150 (4%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAA 608
            LP+   S SSS ++  +P +  R     + S    V  ++     SL  S+S        
Sbjct: 964  LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGP-SLSGSKSPCPQEK-- 1020

Query: 609  SAKSKVSSSSGTTPFSSA--AALPPG-SYASLGRIRTRRQSSGSATNVASTPDNRGRSRA 665
            S  S V S  G+    +   ++ PPG SY  +  ++ + QS  S  + + T     R   
Sbjct: 1021 SKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSH 1080

Query: 666  KVVSQSQRSRSANPAGAGSRSSSPGKLLGS 695
                  Q     +P G  SRSSSP   L S
Sbjct: 1081 SESPSLQSKSQTSPKGGRSRSSSPVTELAS 1110


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 91/358 (25%), Positives = 137/358 (38%), Gaps = 48/358 (13%)

Query: 526 HTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGST----TSRA 581
           H+  SS+  +L SH  +S S   L    R       S     S   SP+G +      R 
Sbjct: 255 HSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRN 314

Query: 582 STVSTKSVSTTGSLQRSRSDIDVNAAAS--AKSKVSSSSGTTPFSSAAALPPGSYAS--- 636
                +S +  G    + S  D  ++ S   + K ++++ T P     +  P S  S   
Sbjct: 315 GGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQG 374

Query: 637 --------LGRIRTRRQSSGSATNVASTPDNRGRSRAKVV-----SQS-QRSRSANPAGA 682
                    GR R RR+    + + AS P  RGR R +       S+S  R+RS++ +G+
Sbjct: 375 RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS 434

Query: 683 GSRSSSPGKLLGS--GYGGLTGGSSRGPP--------VTPSSEKRSKIPRSQGCSRETSP 732
           G  +  PG   GS  G+GG    +   PP         +P +  R   P  +  SR   P
Sbjct: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP 494

Query: 733 NRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPL--DRFGLGQPGRIPGSVNA 790
           +    + SSR P  S S+   +      SR  SP +   PL  D+ G G+          
Sbjct: 495 HPRSWS-SSRSPSKSRSRSAEK-RPHSPSRSPSPKK---PLSRDKDGEGRARHSEAEATR 549

Query: 791 MRVLSTS--------TDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSY 840
            R  S S         D  + +        R+R  PY   S   ++S  SS  S RS+
Sbjct: 550 ARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSH 607



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 57/207 (27%), Positives = 75/207 (36%), Gaps = 70/207 (33%)

Query: 641 RTRRQSSGSATNVASTP---DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGY 697
           R+ R SSGS+ + + +    D+R  SR     + +  ++ +   +GSRS SP    GSG+
Sbjct: 251 RSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG--GSGW 308

Query: 698 G---------------GLTGGSSRGPPVTPSSE-------------------KRSKIPRS 723
           G               G   GS+  PP  PSS                    K S  PRS
Sbjct: 309 GSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRS 368

Query: 724 QGCSRETSPNRIGLA----------------------RSSRIPRPSMSQGCSRDTSR-ES 760
              S+       G A                      R  R PRP+  +G SR  SR  S
Sbjct: 369 APSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARS 428

Query: 761 SRDTSPARGFPPLDRFGLGQPGRIPGS 787
           S D+   RG P         PG  PGS
Sbjct: 429 SSDSGSGRGAP--------GPGPEPGS 447


>gi|57222563 colonic and hepatic tumor over-expressed protein
           isoform b [Homo sapiens]
          Length = 1972

 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 99/541 (18%), Positives = 197/541 (36%), Gaps = 58/541 (10%)

Query: 53  GLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQ 112
           GL   +V  SN  V L G++     V       K   G V+  ++ ++ +   +  ++  
Sbjct: 51  GLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTT-GEVVSGVVSKVFNQPKAKAKELG 109

Query: 113 TLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHI 172
             +  +  +    + V + +L G  +KN +        L   L+  G++ + L  I+  +
Sbjct: 110 IEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVL 169

Query: 173 CNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNM 232
             L       VRD A    VEIYR + + +R  L                          
Sbjct: 170 PKLFESREKAVRDEAKLIAVEIYRWIRDALRPPLQN------------------------ 205

Query: 233 IQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKE 292
           I S   K  ++E                K P S+ R      +++   + L  + SA  +
Sbjct: 206 INSVQLKELEEE--------------WVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGD 251

Query: 293 GAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSD--DKHDWEQRVNALKKIRS 350
             G  D+ D      +VP +  Y   +  E ++K+ +   D  +   W++R  AL+ +  
Sbjct: 252 AEGGGDDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEV 305

Query: 351 LLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAI 410
           L+     E  ++   ++ L    K+  KD    +V  A   L  L+  L  KF   A  +
Sbjct: 306 LIKNPKLEAGDYADLVKALK---KVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHV 362

Query: 411 MPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDL 470
           +PTI          +  +   A+  I   T +  +   + +   +K+  ++++   F+  
Sbjct: 363 VPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIAR 422

Query: 471 LLQEWQTHSLERH-ISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLE 529
             +     +L +  +      + K I+D+  E R  A   +    +      E   +   
Sbjct: 423 SFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAA---FEALGTALKVVGEKAVNPFL 479

Query: 530 SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSV 589
           +   K     +K     V L    ++  ++ +   +PL  + + +G+    A    TK +
Sbjct: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGA----AGDKDTKDI 535

Query: 590 S 590
           S
Sbjct: 536 S 536



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 48/208 (23%), Positives = 94/208 (45%), Gaps = 28/208 (13%)

Query: 20   RLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATS-------------WVN----SS 62
            + Q+   +  +  D+   +D +H    L  +VD L +              W+      +
Sbjct: 1197 KTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDT 1256

Query: 63   NYKVVLLGMDILSALVTRLQDR----FKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
            N  V++  ++ L  L T L +      + +  + +P L+ ++G+ KD +R+ D   +L  
Sbjct: 1257 NTSVLMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRK-DVRAILNR 1315

Query: 119  MDQAANPQYVWDRMLGGFKHKNFRTREGICL----CLIATLNASGAQTLTLSKIVPHICN 174
            M        ++  ++ G K KN + R   CL    CL+ +   +  Q  T  K +  I  
Sbjct: 1316 MCLVYPASKMFPFIMEGTKSKNSKQRAE-CLEELGCLVESYGMNVCQP-TPGKALKEIAV 1373

Query: 175  LLGDPNSQVRDAAINSLVEIYRHVGERV 202
             +GD ++ VR+AA+N++V +Y   G++V
Sbjct: 1374 HIGDRDNAVRNAALNTIVTVYNVHGDQV 1401



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 6/246 (2%)

Query: 62  SNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQ 121
           +N++V+ + + I+ AL+ +  +  K     VL  L+D++GD K     ++   +  I + 
Sbjct: 653 TNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEA--MTAIAEA 709

Query: 122 AANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNS 181
              P      +   F  KN + +      L   +   G   L +   + ++   L   N 
Sbjct: 710 CMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNP 769

Query: 182 QVRDAAINSLVEIYRHVGERVRADL-SKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
            VR AAI  L  +Y +VG  +R     +K    S+++  F K             +    
Sbjct: 770 AVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHST 829

Query: 241 FDDEDSVDGNRPSSASSTSSKAPPSSR--RNVGMGTTRRLGSSTLGSKSSAAKEGAGAVD 298
              ++  DG+ P   S+      P +     +      ++G      +     E AG ++
Sbjct: 830 SGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIIN 889

Query: 299 EEDFIK 304
           +  FI+
Sbjct: 890 DAKFIQ 895



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 34/284 (11%)

Query: 50  LVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVRE 109
           LV  L       +N  +V L    L+ L   L+ +F    G V+P+++++  + K  V +
Sbjct: 320 LVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQ 379

Query: 110 QDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIV 169
             Q  +  I       Q + + +L    +KN   ++   L +  +     A TL  S + 
Sbjct: 380 ALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLK 438

Query: 170 PHICNLL---GDPNSQVRDAAINSLVEIYRHVGERV----RADLSKKGLPQSRLNVIFTK 222
           P    LL    D   +VRDAA  +L    + VGE+      AD+ K  L + +      +
Sbjct: 439 PFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVE 498

Query: 223 FDEVQKSGNMIQSANDKNF-------------DDEDSVDGNRP-----SSASSTSSKAPP 264
               +K+G    +A+ K F              D+D+ D + P       A +  +  PP
Sbjct: 499 LIHGKKAG---LAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP 555

Query: 265 SSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDD 308
              +    G     G+   G+K+    E    V+ E  I+  ++
Sbjct: 556 KKGKPAAPG-----GAGNTGTKNKKGLETKEIVEPELSIEVCEE 594



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 105/566 (18%), Positives = 196/566 (34%), Gaps = 39/566 (6%)

Query: 59   VNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
            +N SN  +V   ++IL  L   +    K  +  +   +I  LGD+K++VR      +   
Sbjct: 909  LNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAW 968

Query: 119  MDQAANPQYVWDRMLGG-FKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLG 177
             +Q    +++    L    K +N   R+ +   L   L    +    L   VPH+ + L 
Sbjct: 969  AEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLE 1028

Query: 178  DPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIF----------------T 221
            D N  VR  A ++L     H+G    A  + K  P S+  V+                 T
Sbjct: 1029 DRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPT 1088

Query: 222  KFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPP-SSRRNVGMGTTRRLGS 280
            K       G+        +   ED +  +         +KAP  SS+     G  +++ S
Sbjct: 1089 KATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQG--KKMPS 1146

Query: 281  STLGSKSSAAKEGAGAV----DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKH 336
             T   K    K G   +     +E  +K    + V++   +   +E I +++  +S    
Sbjct: 1147 KT-SLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVA 1205

Query: 337  DWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAK-------DLRSQVVREAC 389
             W Q        +    A A   D+       + G   L  K       D  + V+ +A 
Sbjct: 1206 KWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKAL 1265

Query: 390  ITLGHLSSVLGNKFDH----GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRL 445
              L  L ++L  +  H     A + +P +   +     ++       +  +       ++
Sbjct: 1266 EYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKM 1325

Query: 446  IPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIE 505
             P I     SK+   R  C E L  L++ +  +  +       + I   I D D+  R  
Sbjct: 1326 FPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNA 1385

Query: 506  ARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNS---DSIVSLPQSDRSSSSSQES 562
            A       ++    +   L   L       L+  +K S    S   + Q +     +Q  
Sbjct: 1386 ALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNI 1445

Query: 563  LNRPLSAKRSPTGSTTSRASTVSTKS 588
             +     ++ P    +S+ +   + S
Sbjct: 1446 SSNANMLRKGPAEDMSSKLNQARSMS 1471



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 54/246 (21%), Positives = 98/246 (39%), Gaps = 21/246 (8%)

Query: 1271 DAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLK 1330
            D +   D   L EAV     E L  +P D  D +           ++ +ERK AL  +  
Sbjct: 260  DEVPQIDAYELLEAV-----EILSKLPKDFYDKI---------EAKKWQERKEALESVEV 305

Query: 1331 ITREDSLGVWEEHFKTILLLLLETLG-DKDHSIRALALRVLREILRNQPARFKNYAELTI 1389
            + +   L   +  +  ++  L + +G D +  + ALA + L  +      +F  YA   +
Sbjct: 306  LIKNPKLEAGD--YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVV 363

Query: 1390 MKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKV 1449
               LE  K+   +VV+A +EA   +  +   +   + +  ++   +  I         + 
Sbjct: 364  PTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARS 423

Query: 1450 VERIAKESL-LQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGED-LKPHLAQLT 1507
                   +L   LL      LL+  +++   VR A+   L     V+GE  + P LA + 
Sbjct: 424  FRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV- 482

Query: 1508 GSKMKL 1513
              K+KL
Sbjct: 483  -DKLKL 487


>gi|57164942 colonic and hepatic tumor over-expressed protein
           isoform a [Homo sapiens]
          Length = 2032

 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 99/541 (18%), Positives = 197/541 (36%), Gaps = 58/541 (10%)

Query: 53  GLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQ 112
           GL   +V  SN  V L G++     V       K   G V+  ++ ++ +   +  ++  
Sbjct: 51  GLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTT-GEVVSGVVSKVFNQPKAKAKELG 109

Query: 113 TLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHI 172
             +  +  +    + V + +L G  +KN +        L   L+  G++ + L  I+  +
Sbjct: 110 IEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVL 169

Query: 173 CNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNM 232
             L       VRD A    VEIYR + + +R  L                          
Sbjct: 170 PKLFESREKAVRDEAKLIAVEIYRWIRDALRPPLQN------------------------ 205

Query: 233 IQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKE 292
           I S   K  ++E                K P S+ R      +++   + L  + SA  +
Sbjct: 206 INSVQLKELEEE--------------WVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGD 251

Query: 293 GAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSD--DKHDWEQRVNALKKIRS 350
             G  D+ D      +VP +  Y   +  E ++K+ +   D  +   W++R  AL+ +  
Sbjct: 252 AEGGGDDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEV 305

Query: 351 LLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAI 410
           L+     E  ++   ++ L    K+  KD    +V  A   L  L+  L  KF   A  +
Sbjct: 306 LIKNPKLEAGDYADLVKALK---KVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHV 362

Query: 411 MPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDL 470
           +PTI          +  +   A+  I   T +  +   + +   +K+  ++++   F+  
Sbjct: 363 VPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIAR 422

Query: 471 LLQEWQTHSLERH-ISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLE 529
             +     +L +  +      + K I+D+  E R  A   +    +      E   +   
Sbjct: 423 SFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAA---FEALGTALKVVGEKAVNPFL 479

Query: 530 SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSV 589
           +   K     +K     V L    ++  ++ +   +PL  + + +G+    A    TK +
Sbjct: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGA----AGDKDTKDI 535

Query: 590 S 590
           S
Sbjct: 536 S 536



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 48/208 (23%), Positives = 94/208 (45%), Gaps = 28/208 (13%)

Query: 20   RLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATS-------------WVN----SS 62
            + Q+   +  +  D+   +D +H    L  +VD L +              W+      +
Sbjct: 1197 KTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDT 1256

Query: 63   NYKVVLLGMDILSALVTRLQDR----FKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
            N  V++  ++ L  L T L +      + +  + +P L+ ++G+ KD +R+ D   +L  
Sbjct: 1257 NTSVLMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRK-DVRAILNR 1315

Query: 119  MDQAANPQYVWDRMLGGFKHKNFRTREGICL----CLIATLNASGAQTLTLSKIVPHICN 174
            M        ++  ++ G K KN + R   CL    CL+ +   +  Q  T  K +  I  
Sbjct: 1316 MCLVYPASKMFPFIMEGTKSKNSKQRAE-CLEELGCLVESYGMNVCQP-TPGKALKEIAV 1373

Query: 175  LLGDPNSQVRDAAINSLVEIYRHVGERV 202
             +GD ++ VR+AA+N++V +Y   G++V
Sbjct: 1374 HIGDRDNAVRNAALNTIVTVYNVHGDQV 1401



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 6/246 (2%)

Query: 62  SNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQ 121
           +N++V+ + + I+ AL+ +  +  K     VL  L+D++GD K     ++   +  I + 
Sbjct: 653 TNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEA--MTAIAEA 709

Query: 122 AANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNS 181
              P      +   F  KN + +      L   +   G   L +   + ++   L   N 
Sbjct: 710 CMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNP 769

Query: 182 QVRDAAINSLVEIYRHVGERVRADL-SKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
            VR AAI  L  +Y +VG  +R     +K    S+++  F K             +    
Sbjct: 770 AVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHST 829

Query: 241 FDDEDSVDGNRPSSASSTSSKAPPSSR--RNVGMGTTRRLGSSTLGSKSSAAKEGAGAVD 298
              ++  DG+ P   S+      P +     +      ++G      +     E AG ++
Sbjct: 830 SGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIIN 889

Query: 299 EEDFIK 304
           +  FI+
Sbjct: 890 DAKFIQ 895



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 34/284 (11%)

Query: 50  LVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVRE 109
           LV  L       +N  +V L    L+ L   L+ +F    G V+P+++++  + K  V +
Sbjct: 320 LVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQ 379

Query: 110 QDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIV 169
             Q  +  I       Q + + +L    +KN   ++   L +  +     A TL  S + 
Sbjct: 380 ALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLK 438

Query: 170 PHICNLL---GDPNSQVRDAAINSLVEIYRHVGERV----RADLSKKGLPQSRLNVIFTK 222
           P    LL    D   +VRDAA  +L    + VGE+      AD+ K  L + +      +
Sbjct: 439 PFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVE 498

Query: 223 FDEVQKSGNMIQSANDKNF-------------DDEDSVDGNRP-----SSASSTSSKAPP 264
               +K+G    +A+ K F              D+D+ D + P       A +  +  PP
Sbjct: 499 LIHGKKAG---LAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP 555

Query: 265 SSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDD 308
              +    G     G+   G+K+    E    V+ E  I+  ++
Sbjct: 556 KKGKPAAPG-----GAGNTGTKNKKGLETKEIVEPELSIEVCEE 594



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 105/566 (18%), Positives = 196/566 (34%), Gaps = 39/566 (6%)

Query: 59   VNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
            +N SN  +V   ++IL  L   +    K  +  +   +I  LGD+K++VR      +   
Sbjct: 909  LNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAW 968

Query: 119  MDQAANPQYVWDRMLGG-FKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLG 177
             +Q    +++    L    K +N   R+ +   L   L    +    L   VPH+ + L 
Sbjct: 969  AEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLE 1028

Query: 178  DPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIF----------------T 221
            D N  VR  A ++L     H+G    A  + K  P S+  V+                 T
Sbjct: 1029 DRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPT 1088

Query: 222  KFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPP-SSRRNVGMGTTRRLGS 280
            K       G+        +   ED +  +         +KAP  SS+     G  +++ S
Sbjct: 1089 KATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQG--KKMPS 1146

Query: 281  STLGSKSSAAKEGAGAV----DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKH 336
             T   K    K G   +     +E  +K    + V++   +   +E I +++  +S    
Sbjct: 1147 KT-SLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVA 1205

Query: 337  DWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAK-------DLRSQVVREAC 389
             W Q        +    A A   D+       + G   L  K       D  + V+ +A 
Sbjct: 1206 KWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKAL 1265

Query: 390  ITLGHLSSVLGNKFDH----GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRL 445
              L  L ++L  +  H     A + +P +   +     ++       +  +       ++
Sbjct: 1266 EYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKM 1325

Query: 446  IPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIE 505
             P I     SK+   R  C E L  L++ +  +  +       + I   I D D+  R  
Sbjct: 1326 FPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNA 1385

Query: 506  ARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNS---DSIVSLPQSDRSSSSSQES 562
            A       ++    +   L   L       L+  +K S    S   + Q +     +Q  
Sbjct: 1386 ALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNI 1445

Query: 563  LNRPLSAKRSPTGSTTSRASTVSTKS 588
             +     ++ P    +S+ +   + S
Sbjct: 1446 SSNANMLRKGPAEDMSSKLNQARSMS 1471



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 54/246 (21%), Positives = 98/246 (39%), Gaps = 21/246 (8%)

Query: 1271 DAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLK 1330
            D +   D   L EAV     E L  +P D  D +           ++ +ERK AL  +  
Sbjct: 260  DEVPQIDAYELLEAV-----EILSKLPKDFYDKI---------EAKKWQERKEALESVEV 305

Query: 1331 ITREDSLGVWEEHFKTILLLLLETLG-DKDHSIRALALRVLREILRNQPARFKNYAELTI 1389
            + +   L   +  +  ++  L + +G D +  + ALA + L  +      +F  YA   +
Sbjct: 306  LIKNPKLEAGD--YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVV 363

Query: 1390 MKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKV 1449
               LE  K+   +VV+A +EA   +  +   +   + +  ++   +  I         + 
Sbjct: 364  PTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARS 423

Query: 1450 VERIAKESL-LQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGED-LKPHLAQLT 1507
                   +L   LL      LL+  +++   VR A+   L     V+GE  + P LA + 
Sbjct: 424  FRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV- 482

Query: 1508 GSKMKL 1513
              K+KL
Sbjct: 483  -DKLKL 487


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 65/227 (28%), Positives = 98/227 (43%), Gaps = 20/227 (8%)

Query: 550 PQSDRSSSSSQESL---NRPLSAKRS--PTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV 604
           P S  SS  S+ES    +RP S   +  P  +TT   S  ST S S+ GS   +   +  
Sbjct: 35  PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL--LPA 92

Query: 605 NAAASAKSKVSSSSGTTPFSSAAALPPGSYASL--GRIRTRRQSSGSATNVASTPDNRGR 662
           +   S  S+ S++S ++P S+  AL PGS  +L  G+  T   SS  +T+    PD+   
Sbjct: 93  STTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS--T 150

Query: 663 SRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPP---VTPSSEKRSK 719
           + + +V  S R  S+   G+   + SP      G  G +      P     TPS    + 
Sbjct: 151 TSSGIVEASTRVHSS--TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 208

Query: 720 IPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS-RDTSRESSRDTS 765
            P  +  +   SP   G   ++  P  S + G S + T   SS D S
Sbjct: 209 APVEESTTYHRSP---GSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 252



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 67/278 (24%), Positives = 109/278 (39%), Gaps = 35/278 (12%)

Query: 515 SHFSREAEHLYHTLESSYQKALQSHLKNSDS------IVSLPQSDRSSSSSQESLNRPLS 568
           SH    + H     +S+    L  H   S S         LP S  +S  SQES     S
Sbjct: 50  SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 109

Query: 569 AKRSPT----GSTTSRA-STVSTKSVSTTGSLQRS--RSDIDVNAAASAKSKVSSSSGT- 620
              + T    GSTT+ +    ST   S+ GS   +        +    A ++V SS+G+ 
Sbjct: 110 PGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 169

Query: 621 -TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANP 679
            T  S A++  PG    L    T  Q+  ++T+   +P +   +  +  +   RS  + P
Sbjct: 170 RTTLSPASSTSPG----LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 225

Query: 680 AGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRE--TSPNRIGL 737
                 SS+      S    +   S      TPSS   +    + G S E  TS ++ G 
Sbjct: 226 TTHFPASSTTSG--HSEKSTIFHSSPDASGTTPSSAHST----TSGVSEESSTSHSQPGS 279

Query: 738 ARSSRIPRPSMSQGCSRDT--------SRESSRDTSPA 767
             ++  P  + + G S++         S E++ DT+P+
Sbjct: 280 THTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPS 317



 Score = 34.3 bits (77), Expect = 0.96
 Identities = 41/158 (25%), Positives = 63/158 (39%), Gaps = 9/158 (5%)

Query: 542 NSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD 601
           +S +   L Q   +S SSQ S    L    SP G TT+    VST   S   S   +   
Sbjct: 287 DSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPG-TTAAPVEVSTTYHSRPSSTPTTH-- 343

Query: 602 IDVNAAASAKSKVSSSSGTTPFSSAAALPPGS--YASLGRIRTRRQSSGSATNVASTPDN 659
              ++    +S+ S++  ++P S+     PGS   A L    T   SS  + +   +P +
Sbjct: 344 FSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 403

Query: 660 RGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGY 697
              S     S +  SR     G+   ++ PG     GY
Sbjct: 404 TTSSGVSEESTTSHSR----PGSTHTTAFPGSTTMPGY 437


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 66/240 (27%), Positives = 96/240 (40%), Gaps = 39/240 (16%)

Query: 558 SSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVS-S 616
           SS+ S++   S    PT      AS  STKS +       +RS +    A S  S +S S
Sbjct: 7   SSKPSMSLAPSGSSMPTADPKPPASLKSTKSATP------NRSLVPTKPATSRNSVMSPS 60

Query: 617 SSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQR--- 673
           SS +T  +S    P    +S  R+R++ +   + + V++       S+A  V   QR   
Sbjct: 61  SSKSTKSTSTKRAPSNRPSSRSRVRSKAR---TPSRVSTDTRTSKASKASDVRCHQRRGT 117

Query: 674 -SRSANPAGAGSRSS--SPGKLLGSG----YGGLTG----------------GSSRGPPV 710
            SR   P   GSRSS  SP +    G    +G   G                G S G P 
Sbjct: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177

Query: 711 TPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDT---SRESSRDTSPA 767
           T + E+    PR+        P   G+ RSS +     +  C   T   S+E S + SP+
Sbjct: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPS 237



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 59/232 (25%), Positives = 94/232 (40%), Gaps = 14/232 (6%)

Query: 555 SSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKV 614
           S+ S  +S ++  S +RS +GS     S V + S     S  RSR+   + +     S+ 
Sbjct: 273 STRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQS 332

Query: 615 SSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRS 674
            S S     + +     G   +  R  ++ +S   + + +   D+RG S  +  S   +S
Sbjct: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQS 392

Query: 675 RSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP-RSQGCSRETSPN 733
            S N     SRS SP K            S    P       RS+ P +++ CSR  SP 
Sbjct: 393 GSPNKQRDHSRSRSPNK--------ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPY 444

Query: 734 RIGLARSSRIPRPSMSQGCSR--DTSRESSRDTSPARGFPPLDRFGLGQPGR 783
           +      SR P  +     SR  + +R+ SR  SP++     D   LG P +
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSK---ERDHSQLGSPSK 493



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/280 (25%), Positives = 112/280 (40%), Gaps = 37/280 (13%)

Query: 500 SEARIEARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSS 559
           S AR   RK   G  S   R ++   H+   S  ++       S +    P  +RS S S
Sbjct: 312 SRARSRTRK---GILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHS 368

Query: 560 QESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSG 619
           + S     S +R   GS++ R  +  ++S S       SRS     A   ++S+      
Sbjct: 369 RSS-----SKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSR------ 417

Query: 620 TTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDN-RGRSRAKVVSQSQ---RSR 675
                         Y +  R R+R  +     + + +P   R RSR++  ++++   RSR
Sbjct: 418 ------------SPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSR 465

Query: 676 SANPAGAGSRSSSPGKLLG-SGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRE----T 730
           S N A   SRS SP K    S  G  +         +PS E++ +  RS    R+     
Sbjct: 466 SPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSR 525

Query: 731 SPNRIGLARSSRIPRPSMSQGCSRDTS--RESSRDTSPAR 768
           SP++    R SR P     +  SR  S  RE  +  SP++
Sbjct: 526 SPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK 565



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 16/179 (8%)

Query: 541 KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS 600
           +NS    S  +S +S+S+ +   NRP S  R       S+A T S  S  T  S     S
Sbjct: 53  RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSR-----VRSKARTPSRVSTDTRTSKASKAS 107

Query: 601 DIDVNAAASAKSKVSSSSGTTP---FSSAAALPPGSYASLGRIRTRRQSSGSATNVASTP 657
           D+  +     + + + S G TP    S ++   P   ++ GRIRT     G A+ V +  
Sbjct: 108 DVRCH-----QRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPT 162

Query: 658 DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEK 716
             +  SR K      R R++N   + S+  +  K      GG   G S    VTPS+ K
Sbjct: 163 SQQKGSRGKSYG---RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 77/322 (23%), Positives = 123/322 (38%), Gaps = 46/322 (14%)

Query: 552  SDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV------N 605
            S+++SS SQ  +N   S   SPT +T+S ASTV   S + + S    R  + V      N
Sbjct: 1950 SNQNSSGSQ--VNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSN 2007

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGS----YASLGRIRTRRQSSGSATNVASTPDNRG 661
            A  +  +  +S++ T P ++   +P        +S        Q  G + N  S  D   
Sbjct: 2008 ATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRN--SPLDCGS 2065

Query: 662  RSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP 721
             S  KV S S++   + P    + +  P     SG       + + PP + S E R  + 
Sbjct: 2066 ASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSG-SSSAHSNQQQPPGSVSQEPRPPLQ 2124

Query: 722  RSQGCSRETSPNRIGLARSS-----------RIPRPSMSQGCSRDTSRESS--------R 762
            +SQ    E       LA SS             P P    GC + T +  +         
Sbjct: 2125 QSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHG 2184

Query: 763  DTSPARGFPPLDRFGLG--------QPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRR 814
             T+P +    +    +         +P  +P SV     LST +  + +V  A  KP+  
Sbjct: 2185 TTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPA-NKPIAP 2243

Query: 815  RYE---PYGMYSDDDANSDASS 833
             +    P+G +S    NS  S+
Sbjct: 2244 NFSAPLPFGPFSTLFENSPTSA 2265


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 77/322 (23%), Positives = 123/322 (38%), Gaps = 46/322 (14%)

Query: 552  SDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV------N 605
            S+++SS SQ  +N   S   SPT +T+S ASTV   S + + S    R  + V      N
Sbjct: 1699 SNQNSSGSQ--VNSAGSLTSSPTTTTSSSASTVPGTSTNGSPSSPSVRRQLFVTVVKTSN 1756

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGS----YASLGRIRTRRQSSGSATNVASTPDNRG 661
            A  +  +  +S++ T P ++   +P        +S        Q  G + N  S  D   
Sbjct: 1757 ATTTTVTTTASNNNTAPTNATYPMPTAKEHYPVSSPSSPSPPAQPGGVSRN--SPLDCGS 1814

Query: 662  RSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP 721
             S  KV S S++   + P    + +  P     SG       + + PP + S E R  + 
Sbjct: 1815 ASPNKVASSSEQEAGSPPVVETTNTRPPNSSSSSG-SSSAHSNQQQPPGSVSQEPRPPLQ 1873

Query: 722  RSQGCSRETSPNRIGLARSS-----------RIPRPSMSQGCSRDTSRESS--------R 762
            +SQ    E       LA SS             P P    GC + T +  +         
Sbjct: 1874 QSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYPMPQTPMGCPQPTPKMETPAIRPPPHG 1933

Query: 763  DTSPARGFPPLDRFGLG--------QPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRR 814
             T+P +    +    +         +P  +P SV     LST +  + +V  A  KP+  
Sbjct: 1934 TTAPHKNSASVQNSSVAVLSVNHIKRPHSVPSSVQLPSTLSTQSACQNSVHPA-NKPIAP 1992

Query: 815  RYE---PYGMYSDDDANSDASS 833
             +    P+G +S    NS  S+
Sbjct: 1993 NFSAPLPFGPFSTLFENSPTSA 2014


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 62/218 (28%), Positives = 87/218 (39%), Gaps = 33/218 (15%)

Query: 563 LNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTP 622
           L R +  +R       S +   +    +  G   R +S  +   +  AK   SSSSGT P
Sbjct: 482 LRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQP 541

Query: 623 FSSAAALP------------PGSYASLG---RIRTRRQSSGSATNVASTPDNRG---RSR 664
              A A P            PGS+AS     R R+R +S  +     ST   RG   RSR
Sbjct: 542 APPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSR 601

Query: 665 AKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQ 724
           ++   + +R RSA+P  A S SSS  +    G     GGS +          RS+  +  
Sbjct: 602 SR-EKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKK-----KKKRSRSRGEKRS 655

Query: 725 GCSRETSPNRIGLARSSRIPRPSMSQGC-SRDTSRESS 761
           G   E +P        +  P PS S  C  RD+ R  +
Sbjct: 656 GDGSEKAP--------APAPPPSGSTSCGDRDSRRRGA 685


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 57/260 (21%)

Query: 550 PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
           P  D    S  ES +   S  RSPT     + + +++   S            D  AAA+
Sbjct: 295 PTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGS------------DEEAAAA 342

Query: 610 AKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVS 669
           A +  +++SG T     A   PG  A       RR+SS S+++ +++  +  RS ++  S
Sbjct: 343 AAA--AAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSS 400

Query: 670 QSQ--------------RSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSE 715
           +S+              RSRS + + + SR  S  +  G  + G  GGS  G   + S  
Sbjct: 401 RSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSG--GGSRDGHRYSRSPA 458

Query: 716 KRSKI-PRSQGCSR--------------------------ETSPNRIGLARSSRIPRPSM 748
           +R    PR +  SR                            SP+R      SR   PS 
Sbjct: 459 RRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSP 518

Query: 749 SQGCSRDTSRESSRDTSPAR 768
           SQ  SR  SR  S   SPAR
Sbjct: 519 SQSRSRSRSRSQSPSPSPAR 538


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 71/264 (26%), Positives = 110/264 (41%), Gaps = 24/264 (9%)

Query: 550  PQSDRSSSSSQESL---NRPLSAKRS--PTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV 604
            P S  SS  S+ES    +RP S   +  P  +TT   S  ST S S+ GS   +   +  
Sbjct: 982  PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL--LPA 1039

Query: 605  NAAASAKSKVSSSSGTTPFSSAAALPPGSYASL--GRIRTRRQSSGSATNVASTPDNRGR 662
            +   S  S+ S++S ++  S+  AL PGS  +L  G+  T   S+  +T+    PD+   
Sbjct: 1040 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS--T 1097

Query: 663  SRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPP---VTPSSEKRSK 719
            + + +V  S R  S+   G+   + SP      G  G +      P     TPS    + 
Sbjct: 1098 TSSGIVEASTRVHSS--TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 1155

Query: 720  IPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS-RDTSRESSRD---TSPARGFPPLDR 775
             P  +  +   SP   G   ++  P  S + G S + T   SS D   T+P+        
Sbjct: 1156 APVEESTTYHRSP---GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 1212

Query: 776  FGLGQPGRI-PGSVNAMRVLSTST 798
             G     RI PGS     +  ++T
Sbjct: 1213 RGESTTSRISPGSTEITTLPGSTT 1236



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 61/219 (27%), Positives = 86/219 (39%), Gaps = 36/219 (16%)

Query: 572  SPTGSTTSRASTVSTKSVSTTGSLQRSR-SDIDVNAAASAKSKVSSSSGTTPFSSAAALP 630
            SP  STTS     ST   S+ GS Q     +    +  S +S+ S SS T   SS    P
Sbjct: 1899 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS----P 1954

Query: 631  PGSYASLGRIRTRRQSSGSATNVASTPDN---RGRSRAKVVSQSQR---------SRSAN 678
            P + ++L    T   SS  +T     PD+    GRS     S S +         +RS  
Sbjct: 1955 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 2014

Query: 679  PAGAGSRSSSPGKLLGSGYGGLTG--GSSRGPPVTPSSEKRSKIPR------------SQ 724
                G  ++SP   + SG    T   GS+  P ++  S      PR            S 
Sbjct: 2015 SVLLGESTTSP---ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSS 2071

Query: 725  GCSRE--TSPNRIGLARSSRIPRPSMSQGCSRDTSRESS 761
            G S E  TS +R G   ++  P  + + G SR ++   S
Sbjct: 2072 GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 61/219 (27%), Positives = 85/219 (38%), Gaps = 36/219 (16%)

Query: 572  SPTGSTTSRASTVSTKSVSTTGSLQRSR-SDIDVNAAASAKSKVSSSSGTTPFSSAAALP 630
            SP  STTS     ST   S+ GS Q     + D  +    +S  S SS T   SSA    
Sbjct: 3456 SPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA---- 3511

Query: 631  PGSYASLGRIRTRRQSSGSATNVASTPDN---RGRSRAKVVSQSQR---------SRSAN 678
            P + ++L    T   SS  +T     PD+    GRS     S S +         +RS  
Sbjct: 3512 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571

Query: 679  PAGAGSRSSSPGKLLGSGYGGLTG--GSSRGPPVTPSSEKRSKIPR------------SQ 724
                G  ++SP   + SG    T   GS+  P ++  S      PR            S 
Sbjct: 3572 SVLLGESTTSP---ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSS 3628

Query: 725  GCSRE--TSPNRIGLARSSRIPRPSMSQGCSRDTSRESS 761
            G S E  TS +R G   ++  P  + + G SR ++   S
Sbjct: 3629 GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 3667



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 63/250 (25%), Positives = 92/250 (36%), Gaps = 18/250 (7%)

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQR 597
            S +    P S  +S  S+ES     S   +     P  STTS     ST S  ++GS++ 
Sbjct: 3531 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 3590

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVAS 655
            +   +  +      S+ S++  ++P S A  L P S  S G     T   S   +T+  +
Sbjct: 3591 TA--LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 3648

Query: 656  TPDNR---GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 712
             PD+    G SR    S S    +       S ++S     GS     T  SS G   T 
Sbjct: 3649 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-----GSSQESTTSHSSSGSTDTA 3703

Query: 713  SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
             S   S    S G    T  +  G   ++  P  + S G    ++R  S   SP     P
Sbjct: 3704 LS-PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 3762

Query: 773  LDRFGLGQPG 782
                  G  G
Sbjct: 3763 ASSTSPGLQG 3772



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 9/144 (6%)

Query: 543  SDSIVSLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQR 597
            S    +LP S  ++  S++S       R      SP  +T+S  S  ST S S  GS+  
Sbjct: 4312 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHT 4371

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGS--YASLGRIRTRRQSSGSATNVAS 655
            +      +      S+ S++S ++P S+   L PGS   +SLG   T   SS  +T    
Sbjct: 4372 TA--FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 4429

Query: 656  TPDNRGRSRAKVVSQSQRSRSANP 679
             PDN   S     S    S + +P
Sbjct: 4430 LPDNTTASGLLEASTPVHSSTGSP 4453



 Score = 41.2 bits (95), Expect = 0.008
 Identities = 67/280 (23%), Positives = 105/280 (37%), Gaps = 24/280 (8%)

Query: 515  SHFSREAEHLYHTLESSYQKALQSHLKNSDS------IVSLPQSDRSSSSSQESLNRPLS 568
            SH    + H     +S+    L  H   S S         LP S  +S SSQES     S
Sbjct: 3637 SHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSS 3696

Query: 569  AKRSPT----GSTTSRA-STVSTKSVSTTGSLQRS--RSDIDVNAAASAKSKVSSSSGT- 620
            +  + T    GSTT+ +    ST   S+ GS   +        +    A ++V SS+G+ 
Sbjct: 3697 SGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 3756

Query: 621  -TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANP 679
             T  S A++  PG    L    T  Q+  ++T+   +P +   +  +  +   RS  + P
Sbjct: 3757 RTTLSPASSTSPG----LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 3812

Query: 680  AGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLAR 739
                  SS+      S    +   S      TPSS   +   R +  +   SP   G   
Sbjct: 3813 TTHFPASSTTSG--HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP---GSTE 3867

Query: 740  SSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLG 779
             + +P  + + G S  ++   S   SP     P     LG
Sbjct: 3868 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 3907



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 62/250 (24%), Positives = 92/250 (36%), Gaps = 18/250 (7%)

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQR 597
            S +    P S  +S  S+ES     S   +     P  STTS     ST S  ++GS++ 
Sbjct: 891  STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 950

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVAS 655
            +   +  +      S+ S++  ++P S A  L P S  S G     T  +S   +T+  +
Sbjct: 951  TA--LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA 1008

Query: 656  TPDNR---GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 712
             PD+    G SR    S S    +       S ++S     G      T  SS G   T 
Sbjct: 1009 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-----GPSQESTTSHSSSGSTDTA 1063

Query: 713  SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
             S   S    S G    T  +  G   ++  P  + S G    ++R  S   SP     P
Sbjct: 1064 LS-PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 1122

Query: 773  LDRFGLGQPG 782
                  G  G
Sbjct: 1123 ASSTSPGLQG 1132



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 41/144 (28%), Positives = 60/144 (41%), Gaps = 9/144 (6%)

Query: 543  SDSIVSLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQR 597
            S    +LP S  ++  S++S       R      SP  +T+S  S  ST S S  GS   
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1731

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVAS 655
            +      +      S+ S++S ++P S+   L PGS   +SLG   T   SS  +T    
Sbjct: 1732 TA--FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 1789

Query: 656  TPDNRGRSRAKVVSQSQRSRSANP 679
             PDN   S     S    S + +P
Sbjct: 1790 LPDNTTASGLLEASTPVHSSTGSP 1813



 Score = 40.0 bits (92), Expect = 0.017
 Identities = 62/250 (24%), Positives = 91/250 (36%), Gaps = 18/250 (7%)

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQR 597
            S +    P S  +S  S+ES     S   +     P  STTS     ST S  ++GS++ 
Sbjct: 1974 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 2033

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVAS 655
            +   +  +      S+ S++  ++P S A  L P S  S G     T   S   +T+  +
Sbjct: 2034 TA--LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 2091

Query: 656  TPDNR---GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 712
             PD+    G SR    S S    +       S ++S     G      T  SS G   T 
Sbjct: 2092 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-----GPSQESTTSHSSPGSTDTA 2146

Query: 713  SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
             S   S    S G    T  +  G   ++  P  + S G    ++R  S   SP     P
Sbjct: 2147 LS-PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 2205

Query: 773  LDRFGLGQPG 782
                  G  G
Sbjct: 2206 ASSTSPGLQG 2215



 Score = 38.1 bits (87), Expect = 0.066
 Identities = 44/151 (29%), Positives = 60/151 (39%), Gaps = 8/151 (5%)

Query: 540 LKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSR 599
           L  S +   L +   +  SS  S +R LS  R+ T S  S  ST S      T ++    
Sbjct: 267 LPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART-TSSGVSEKSTTSHSRPGPTHTIAFPD 325

Query: 600 SDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVASTP 657
           S           S+ S++S + P S+   L PG+   +SLG   T   SS   T     P
Sbjct: 326 S-----TTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLP 380

Query: 658 DNRGRSRAKVVSQSQRSRSANPAGAGSRSSS 688
           DN   S     S    S + +P    S SSS
Sbjct: 381 DNTTTSGLLEASTPVHSSTGSPHTTLSPSSS 411



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 75/342 (21%), Positives = 124/342 (36%), Gaps = 77/342 (22%)

Query: 527  TLESSYQKALQSHL-KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT----GSTT--- 578
            T     +++  SH  +++   + LP    +S    ES   P+S+    T    GSTT   
Sbjct: 1985 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 2044

Query: 579  -------------SRASTVSTKSVSTTGSLQRSRSD------------------------ 601
                         S A+T+S  S +++G  + S +                         
Sbjct: 2045 LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH 2104

Query: 602  ---------------IDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASL--GRIRTRR 644
                           +  +   S  S+ S++S ++P S+  AL PGS  +L  G+  T  
Sbjct: 2105 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF 2164

Query: 645  QSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGS 704
             SS  +T+    PD+   + + +V  S R  S+   G+   + SP      G  G +   
Sbjct: 2165 HSSPGSTHTTLFPDS--TTSSGIVEASTRVHSS--TGSPRTTLSPASSTSPGLQGESTAF 2220

Query: 705  SRGPP---VTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS-RDTSRES 760
               P     TPS    +  P  +  +   SP   G   ++  P  S + G S + T   S
Sbjct: 2221 QTHPASTHTTPSPPSTATAPVEESTTYHRSP---GSTPTTHFPASSTTSGHSEKSTIFHS 2277

Query: 761  SRD---TSPARGFPPLDRFGLGQPGRI-PGSVNAMRVLSTST 798
            S D   T+P+         G     RI PGS     +  ++T
Sbjct: 2278 SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 2319



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 9/125 (7%)

Query: 542  NSDSIVSLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQ 596
            +S    +LP S  + S S++S       R   A  SP  +T+S  S  S+ S S  GS  
Sbjct: 2977 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 3036

Query: 597  RSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGS--YASLGRIRTRRQSSGSATNVA 654
             +      +   S  S+  ++S ++  S+ A L PGS   +SLG+  T   SS   T   
Sbjct: 3037 TTA--FPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 3094

Query: 655  STPDN 659
              PD+
Sbjct: 3095 LLPDD 3099



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 9/125 (7%)

Query: 542  NSDSIVSLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQ 596
            +S    +LP S  + S S++S       R   A  SP  +T+S  S  S+ S S  GS  
Sbjct: 4060 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 4119

Query: 597  RSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGS--YASLGRIRTRRQSSGSATNVA 654
             +      +   S  S+  ++S ++  S+ A L PGS   +SLG+  T   SS   T   
Sbjct: 4120 TTA--FPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 4177

Query: 655  STPDN 659
              PD+
Sbjct: 4178 LLPDD 4182



 Score = 36.2 bits (82), Expect = 0.25
 Identities = 56/242 (23%), Positives = 90/242 (37%), Gaps = 14/242 (5%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD---IDVN 605
            LP +  ++   +ES   P S+  + T  + +R++T      ST   L  S ++   +  +
Sbjct: 2454 LPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 2513

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNR--- 660
                + S+ S++  T+P S  A L P +  S G     +   S   +T+  + PD+    
Sbjct: 2514 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTP 2573

Query: 661  GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720
            G SR    S S    +       S ++S     G      T  SS G   T  S   S  
Sbjct: 2574 GLSRHSTTSHSSPGSTDTTLLPASTTTS-----GPSQESTTSHSSPGSTDTALS-PGSTT 2627

Query: 721  PRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQ 780
              S G    T  +  G   ++  P  + S G    ++R  S   SP     P      G 
Sbjct: 2628 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 2687

Query: 781  PG 782
             G
Sbjct: 2688 QG 2689



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 67/283 (23%), Positives = 109/283 (38%), Gaps = 45/283 (15%)

Query: 527  TLESSYQKALQSHL-KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT----GSTT--- 578
            T     +++  SH  +++   + LP    +S    ES   P+S+    T    GSTT   
Sbjct: 902  TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 961

Query: 579  -------------SRASTVSTKSVSTTG-----SLQRSR------SDIDVNAAASAKSKV 614
                         S A+T+S  S +++G     +  RSR      +    +      S+ 
Sbjct: 962  LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 1021

Query: 615  SSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQ 672
            S++S ++P S+   L P S  + G  +  T   SS  +T+ A +P   G + A    Q  
Sbjct: 1022 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP---GSTTALSFGQES 1078

Query: 673  RSRSANPAGAGSRSSSPGKLLGSGY--GGLTGGSSRGPPVTPSSEKRSKIPRSQGCSR-- 728
             +  +NP G+   +  P     SG         SS G P T  S   S  P  QG S   
Sbjct: 1079 TTFHSNP-GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAF 1137

Query: 729  ETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFP 771
            +T P       ++  P  + +      T+   S  ++P   FP
Sbjct: 1138 QTHP---ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 1177



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 54/237 (22%), Positives = 90/237 (37%), Gaps = 15/237 (6%)

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQR 597
            S +    P S  +S  S+ES     S   +     P  STTS     ST S  ++GS++ 
Sbjct: 4614 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 4673

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTP 657
            +   +  +      S+ S++  ++P S+       S  +LGR         S    A+TP
Sbjct: 4674 TA--LPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTP 4731

Query: 658  DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKR 717
                 + + +V +S    S+  +             G      T  SS    ++      
Sbjct: 4732 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791

Query: 718  SKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRD-TSRESSRDTSPARGFPPL 773
            S +   +  S  +SP  I    ++  P  S + G S + T+  SS DT+   G  PL
Sbjct: 4792 SALV-EEPTSYHSSPGSIA---TTHFPESSTTSGRSEESTASHSSPDTN---GITPL 4841



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 51/233 (21%), Positives = 95/233 (40%), Gaps = 22/233 (9%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD---IDVN 605
            LP +  ++   +ES   P S+  + T  + +R++T      ST   L  S ++   +  +
Sbjct: 1371 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 1430

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRS 663
                + S+ S++  T+P S  A L P +  S G     +   S   +T+  + PD+   S
Sbjct: 1431 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 1490

Query: 664  RAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR- 722
                    + + S +  G+   + SPG    S      G  S     +P   + + +P  
Sbjct: 1491 DL----SQEPTTSHSSQGSTEATLSPGSTTASS----LGQQSTTFHSSPGDTETTLLPDD 1542

Query: 723  --SQGCSRETSP--NRIGLARSSRIPRPSMSQGCSRDT----SRESSRDTSPA 767
              + G    ++P  +  G   ++  P  S S G   ++    S  SS DT+P+
Sbjct: 1543 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 1595



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 51/233 (21%), Positives = 95/233 (40%), Gaps = 22/233 (9%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD---IDVN 605
            LP +  ++   +ES   P S+  + T  + +R++T      ST   L  S ++   +  +
Sbjct: 2928 LPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 2987

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRS 663
                + S+ S++  T+P S  A L P +  S G     +   S   +T+  + PD+   S
Sbjct: 2988 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 3047

Query: 664  RAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR- 722
                    + + S +  G+   + SPG    S      G  S     +P   + + +P  
Sbjct: 3048 GL----SQEPTASHSSQGSTEATLSPGSTTASS----LGQQSTTFHSSPGDTETTLLPDD 3099

Query: 723  --SQGCSRETSP--NRIGLARSSRIPRPSMSQGCSRDT----SRESSRDTSPA 767
              + G    ++P  +  G   ++  P  S S G   ++    S  SS DT+P+
Sbjct: 3100 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 3152



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 51/233 (21%), Positives = 95/233 (40%), Gaps = 22/233 (9%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD---IDVN 605
            LP +  ++   +ES   P S+  + T  + +R++T      ST   L  S ++   +  +
Sbjct: 4011 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 4070

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRS 663
                + S+ S++  T+P S  A L P +  S G     +   S   +T+  + PD+   S
Sbjct: 4071 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 4130

Query: 664  RAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR- 722
                    + + S +  G+   + SPG    S      G  S     +P   + + +P  
Sbjct: 4131 GL----SQEPTTSHSSQGSTEATLSPGSTTASS----LGQQSTTFHSSPGDTETTLLPDD 4182

Query: 723  --SQGCSRETSP--NRIGLARSSRIPRPSMSQGCSRDT----SRESSRDTSPA 767
              + G    ++P  +  G   ++  P  S S G   ++    S  SS DT+P+
Sbjct: 4183 TITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPS 4235



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 74/311 (23%), Positives = 111/311 (35%), Gaps = 31/311 (9%)

Query: 548 SLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDI 602
           +LP S      S++S       R       P   T+S  S  ST S S  GS   +    
Sbjct: 622 ALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA--F 679

Query: 603 DVNAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVASTPDNR 660
             +      S+ S++S ++P  +   L PGS   +SLG   T   S   +T     PDN 
Sbjct: 680 PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNT 739

Query: 661 GRS----RAKVVSQSQRS--RSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSS 714
             S     +  V  S RS   + +PAG+ +R           +   +   +R  P T +S
Sbjct: 740 TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTF----HSWPSSKDTRPAPPTTTS 795

Query: 715 EKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLD 774
                   S G     SP+ I     S   R + S      T+  SS  ++    FP  D
Sbjct: 796 AFVEPSTTSHG-----SPSSIPTTHIS--ARSTTSGLVEESTTYHSSPGSTQTMHFPESD 848

Query: 775 -RFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASS 833
              G G+      S     + S  +   A V    ++P      P    +    +S  +S
Sbjct: 849 TTSGRGEESTTSHSSTTHTISSAPSTTSALV----EEPTSYHSSPGSTATTHFPDSSTTS 904

Query: 834 VCSERSYGSRN 844
             SE S  S +
Sbjct: 905 GRSEESTASHS 915



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 69/313 (22%), Positives = 117/313 (37%), Gaps = 64/313 (20%)

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLS------AKRSPTGSTTSRA--STVSTKSVSTTGS 594
            +  +V      R S SS E+   P S      +++S T  T+ R+  +T+S  + +++G 
Sbjct: 2488 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 2547

Query: 595  LQRSRSD---------------------------------------IDVNAAASAKSKVS 615
             + S +                                        +  +   S  S+ S
Sbjct: 2548 SEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 2607

Query: 616  SSSGTTPFSSAAALPPGSYASL--GRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQR 673
            ++S ++P S+  AL PGS  +L  G+  T   SS  +T+    PD+   + + +V  S R
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS--TTSSGIVEASTR 2665

Query: 674  SRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPP---VTPSSEKRSKIPRSQGCSRET 730
              S+   G+   + SP      G  G +      P     TPS    +  P  +  +   
Sbjct: 2666 VHSS--TGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHR 2723

Query: 731  SPNRIGLARSSRIPRPSMSQGCS-RDTSRESSRD---TSPARGFPPLDRFGLGQPGRI-P 785
            SP   G   ++  P  S + G S + T   SS D   T+P+         G     RI P
Sbjct: 2724 SP---GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISP 2780

Query: 786  GSVNAMRVLSTST 798
            GS     +  ++T
Sbjct: 2781 GSTEITTLPGSTT 2793



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 53/222 (23%), Positives = 85/222 (38%), Gaps = 22/222 (9%)

Query: 527  TLESSYQKALQSHL-KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVS 585
            T     +++  SH  +++   + LP    +S    ES   P+S+    T +     +T  
Sbjct: 3542 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 3601

Query: 586  TKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTT---PFSSAAALPPGSYAS--LGRI 640
                STT           ++ A++  S VS  S T+   P S+     P S  +  L R 
Sbjct: 3602 LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH 3661

Query: 641  RTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYG-- 698
             T   SS  +T+    P +   S     S  + + S + +G+   + SPG      +G  
Sbjct: 3662 STTSHSSPGSTDTTLLPASTTTSG----SSQESTTSHSSSGSTDTALSPGSTTALSFGQE 3717

Query: 699  GLTGGSSRG-------PPVTPSS---EKRSKIPRSQGCSRET 730
              T  SS G       P  T SS   E  +++  S G  R T
Sbjct: 3718 STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 3759



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 46/173 (26%), Positives = 65/173 (37%), Gaps = 22/173 (12%)

Query: 572  SPTGSTTSRASTVSTKSVSTTGSLQRSR-SDIDVNAAASAKSKVSSSSGTTPFSSAAALP 630
            SP  STTS     ST   S+ GS Q     + +  +    +S  S SS T   SSA    
Sbjct: 4539 SPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSA---- 4594

Query: 631  PGSYASLGRIRTRRQSSGSATNVASTPDN---RGRSRAKVVSQSQR---------SRSAN 678
            P + ++L    T   SS  +T     PD+    GRS     S S +         +RS  
Sbjct: 4595 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 4654

Query: 679  PAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETS 731
                G  ++SP        G +   +  G   TP   ++S    S   S  T+
Sbjct: 4655 SVLLGESTTSP-----ISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT 4702



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 47/191 (24%), Positives = 78/191 (40%), Gaps = 19/191 (9%)

Query: 550  PQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV 604
            P+S  +S  S+ES     S   +     P   TTS     ST    + GS++ + +    
Sbjct: 4814 PESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTAT 4873

Query: 605  NAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVASTPDNRGR 662
                SAKS +  SS  +P  +   L P S   +S+    T   S   +T+  + P +   
Sbjct: 4874 TPGLSAKSTILYSSSRSPDQT---LSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTT 4930

Query: 663  SRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGG--LTGGSSRGPPVTPSSEKRSKI 720
            S    +SQ   +  + P G+   + SPG +  S +     T  S  G  ++  S   + +
Sbjct: 4931 SG---LSQESTTFHSKP-GSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTV 4986

Query: 721  PRSQGCSRETS 731
            P   G S E++
Sbjct: 4987 P---GLSEEST 4994



 Score = 33.5 bits (75), Expect = 1.6
 Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 14/165 (8%)

Query: 550  PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
            P S  +S  S++S     S   S T + +S  ST S +  STT  +    ++I     ++
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGT-TPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 2792

Query: 610  AKSKVSSSSGT---TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAK 666
                +S +S T   +P S    L P S  SLG      +S+ S +   ST      +   
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLG---VGEESTTSRSQPGSTHSTVSPASTT 2849

Query: 667  VVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVT 711
                S+ S +         SSSPG    + +   T  S RG   T
Sbjct: 2850 TPGLSEESTTV-------YSSSPGSTETTVFPRSTTTSVRGEEPT 2887



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 550  PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
            P S  +S  S++S     S   S T + +S  ST S +  STT  +    ++I     ++
Sbjct: 1177 PASSTTSGHSEKSTIFHSSPDASGT-TPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 1235

Query: 610  AKSKVSSSSGT---TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAK 666
                +S +S T   +P S    L P S  SLG      +S+ S +   ST      +   
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLG---VGEESTTSRSQPGSTHSTVSPASTT 1292

Query: 667  VVSQSQRSRSANPAGAGSRSSS 688
                S+ S +   +  GS  ++
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETT 1314



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 550  PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
            P S  +S  S++S     S   S T + +S  ST S +  STT  +    ++I     ++
Sbjct: 2260 PASSTTSGHSEKSTIFHSSPDASGT-TPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 2318

Query: 610  AKSKVSSSSGT---TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAK 666
                +S +S T   +P S    L P S  SLG      +S+ S +   ST      +   
Sbjct: 2319 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLG---VGEESTTSRSQPGSTHSTVSPASTT 2375

Query: 667  VVSQSQRSRSANPAGAGSRSSS 688
                S+ S +   +  GS  ++
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETT 2397



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 45/216 (20%), Positives = 83/216 (38%), Gaps = 7/216 (3%)

Query: 553  DRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVN--AAASA 610
            D +++S     + P+ +      +T S A + + +  STT     +  D         SA
Sbjct: 4432 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 4491

Query: 611  KSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQ 670
              ++S++S  +P S+       S  +LGR         S    A+TP     + + +V +
Sbjct: 4492 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 4551

Query: 671  SQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRET 730
            S    S+  +             G G    T  SS    ++ +    S +   +  S  +
Sbjct: 4552 STTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALV-EEPTSYHS 4610

Query: 731  SPNRIGLARSSRIPRPSMSQGCSRD-TSRESSRDTS 765
            SP   G   ++  P  S + G S + T+  SS+D +
Sbjct: 4611 SP---GSTATTHFPDSSTTSGRSEESTASHSSQDAT 4643



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 56/263 (21%), Positives = 93/263 (35%), Gaps = 18/263 (6%)

Query: 515  SHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT 574
            +HFS  +     TL  S +         +      P    +S    E    P+S+  + T
Sbjct: 3177 THFSASST----TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 3232

Query: 575  GSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTT---PFSSAAALPP 631
             +     +T      STT        D  ++ A++  S VS  S T+   P S+     P
Sbjct: 3233 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 3292

Query: 632  GSYASLG--RIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSP 689
            GS    G  +  T   SS  +T+   +P   G + A  +     +  + P G+   +  P
Sbjct: 3293 GSTTMPGVSQESTASHSSPGSTDTTLSP---GSTTASSLGPESTTFHSGP-GSTETTLLP 3348

Query: 690  GKLLGSGY--GGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPS 747
                 SG         SS G P T  S   S   + +  + ++ PN      ++  P  +
Sbjct: 3349 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNS---KDTTPAPPTT 3405

Query: 748  MSQGCSRDTSRESSRDTSPARGF 770
             S      T+   S  ++P   F
Sbjct: 3406 TSAFVELSTTSHGSPSSTPTTHF 3428



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 45/216 (20%), Positives = 83/216 (38%), Gaps = 7/216 (3%)

Query: 553  DRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVN--AAASA 610
            D +++S     + P+ +      +T S A + + +  STT     +  D         SA
Sbjct: 3349 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSA 3408

Query: 611  KSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQ 670
              ++S++S  +P S+       S  +LGR         S    A+TP     + + +V +
Sbjct: 3409 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 3468

Query: 671  SQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRET 730
            S    S+  +             G G    T  SS    ++ +    S +   +  S  +
Sbjct: 3469 STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV-EEPTSYHS 3527

Query: 731  SPNRIGLARSSRIPRPSMSQGCSRD-TSRESSRDTS 765
            SP   G   ++  P  S + G S + T+  SS+D +
Sbjct: 3528 SP---GSTATTHFPDSSTTSGRSEESTASHSSQDAT 3560



 Score = 32.0 bits (71), Expect = 4.7
 Identities = 56/268 (20%), Positives = 93/268 (34%), Gaps = 28/268 (10%)

Query: 515  SHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT 574
            +HFS  +     TL  S +         +      P    +S    E    P+S+  + T
Sbjct: 4260 THFSASST----TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 4315

Query: 575  GSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSS----------GTTPFS 624
             +     +T      STT        D  ++ A++  S VS  S           TT F 
Sbjct: 4316 TALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFP 4375

Query: 625  SAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGS 684
            S+  +P  S  S     T   SS  +T+   +P   G + A  +     +  ++P G+  
Sbjct: 4376 SSTTMPGVSQES-----TASHSSPGSTDTTLSP---GSTTASSLGPESTTFHSSP-GSTE 4426

Query: 685  RSSSPGKLLGSGY--GGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSR 742
             +  P     SG         SS G P T  S   S   + +  + ++ PN      ++ 
Sbjct: 4427 TTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNS---KDTTP 4483

Query: 743  IPRPSMSQGCSRDTSRESSRDTSPARGF 770
             P  + S      T+   S  ++P   F
Sbjct: 4484 APPTTTSAFVELSTTSHGSPSSTPTTHF 4511



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 21/174 (12%)

Query: 527  TLESSYQKALQSHL-KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT----GSTT--- 578
            T     +++  SH  +++   + LP    +S    ES   P+S+    T    GSTT   
Sbjct: 4625 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 4684

Query: 579  -SRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASL 637
             S  ST    S S+T +   S S   +      +S+ S++  ++P ++A    P    + 
Sbjct: 4685 LSEKSTTFHSSPSSTPTTHFSASSTTLG-----RSEESTTVHSSPVATATTPSPARSTTS 4739

Query: 638  GRIR--TRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSP 689
            G +   T   SS  +T     P++   S      +S+ SR+++ +   + SS P
Sbjct: 4740 GLVEESTAYHSSPGSTQTMHFPESSTAS-----GRSEESRTSHSSTTHTISSPP 4788


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 71/264 (26%), Positives = 110/264 (41%), Gaps = 24/264 (9%)

Query: 550 PQSDRSSSSSQESL---NRPLSAKRS--PTGSTTSRASTVSTKSVSTTGSLQRSRSDIDV 604
           P S  SS  S+ES    +RP S   +  P  +TT   S  ST S S+ GS   +   +  
Sbjct: 469 PASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL--LPA 526

Query: 605 NAAASAKSKVSSSSGTTPFSSAAALPPGSYASL--GRIRTRRQSSGSATNVASTPDNRGR 662
           +   S  S+ S++S ++  S+  AL PGS  +L  G+  T   S+  +T+    PD+   
Sbjct: 527 STTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDS--T 584

Query: 663 SRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPP---VTPSSEKRSK 719
           + + +V  S R  S+   G+   + SP      G  G +      P     TPS    + 
Sbjct: 585 TSSGIVEASTRVHSS--TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 642

Query: 720 IPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS-RDTSRESSRD---TSPARGFPPLDR 775
            P  +  +   SP   G   ++  P  S + G S + T   SS D   T+P+        
Sbjct: 643 APVEESTTYHRSP---GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 699

Query: 776 FGLGQPGRI-PGSVNAMRVLSTST 798
            G     RI PGS     +  ++T
Sbjct: 700 RGESTTSRISPGSTEITTLPGSTT 723



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 62/250 (24%), Positives = 92/250 (36%), Gaps = 18/250 (7%)

Query: 543 SDSIVSLPQSDRSSSSSQESLNRPLSAKRS-----PTGSTTSRASTVSTKSVSTTGSLQR 597
           S +    P S  +S  S+ES     S   +     P  STTS     ST S  ++GS++ 
Sbjct: 378 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 437

Query: 598 SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVAS 655
           +   +  +      S+ S++  ++P S A  L P S  S G     T  +S   +T+  +
Sbjct: 438 TA--LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA 495

Query: 656 TPDNR---GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTP 712
            PD+    G SR    S S    +       S ++S     G      T  SS G   T 
Sbjct: 496 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS-----GPSQESTTSHSSSGSTDTA 550

Query: 713 SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
            S   S    S G    T  +  G   ++  P  + S G    ++R  S   SP     P
Sbjct: 551 LS-PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 609

Query: 773 LDRFGLGQPG 782
                 G  G
Sbjct: 610 ASSTSPGLQG 619



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 41/144 (28%), Positives = 60/144 (41%), Gaps = 9/144 (6%)

Query: 543  SDSIVSLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQR 597
            S    +LP S  ++  S++S       R      SP  +T+S  S  ST S S  GS   
Sbjct: 1159 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1218

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVAS 655
            +      +      S+ S++S ++P S+   L PGS   +SLG   T   SS  +T    
Sbjct: 1219 TA--FPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 1276

Query: 656  TPDNRGRSRAKVVSQSQRSRSANP 679
             PDN   S     S    S + +P
Sbjct: 1277 LPDNTTASGLLEASTPVHSSTGSP 1300



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 67/283 (23%), Positives = 109/283 (38%), Gaps = 45/283 (15%)

Query: 527 TLESSYQKALQSHL-KNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT----GSTT--- 578
           T     +++  SH  +++   + LP    +S    ES   P+S+    T    GSTT   
Sbjct: 389 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 448

Query: 579 -------------SRASTVSTKSVSTTG-----SLQRSR------SDIDVNAAASAKSKV 614
                        S A+T+S  S +++G     +  RSR      +    +      S+ 
Sbjct: 449 LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 508

Query: 615 SSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQ 672
           S++S ++P S+   L P S  + G  +  T   SS  +T+ A +P   G + A    Q  
Sbjct: 509 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP---GSTTALSFGQES 565

Query: 673 RSRSANPAGAGSRSSSPGKLLGSGY--GGLTGGSSRGPPVTPSSEKRSKIPRSQGCSR-- 728
            +  +NP G+   +  P     SG         SS G P T  S   S  P  QG S   
Sbjct: 566 TTFHSNP-GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAF 624

Query: 729 ETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFP 771
           +T P       ++  P  + +      T+   S  ++P   FP
Sbjct: 625 QTHP---ASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 664



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 51/233 (21%), Positives = 95/233 (40%), Gaps = 22/233 (9%)

Query: 549  LPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD---IDVN 605
            LP +  ++   +ES   P S+  + T  + +R++T      ST   L  S ++   +  +
Sbjct: 858  LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 917

Query: 606  AAASAKSKVSSSSGTTPFSSAAALPPGSYASLG--RIRTRRQSSGSATNVASTPDNRGRS 663
                + S+ S++  T+P S  A L P +  S G     +   S   +T+  + PD+   S
Sbjct: 918  PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 977

Query: 664  RAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPR- 722
                    + + S +  G+   + SPG    S      G  S     +P   + + +P  
Sbjct: 978  DL----SQEPTTSHSSQGSTEATLSPGSTTASS----LGQQSTTFHSSPGDTETTLLPDD 1029

Query: 723  --SQGCSRETSP--NRIGLARSSRIPRPSMSQGCSRDT----SRESSRDTSPA 767
              + G    ++P  +  G   ++  P  S S G   ++    S  SS DT+P+
Sbjct: 1030 TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 1082



 Score = 34.7 bits (78), Expect = 0.73
 Identities = 74/311 (23%), Positives = 111/311 (35%), Gaps = 31/311 (9%)

Query: 548 SLPQSDRSSSSSQESLN-----RPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDI 602
           +LP S      S++S       R       P   T+S  S  ST S S  GS   +    
Sbjct: 109 ALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA--F 166

Query: 603 DVNAAASAKSKVSSSSGTTPFSSAAALPPGSY--ASLGRIRTRRQSSGSATNVASTPDNR 660
             +      S+ S++S ++P  +   L PGS   +SLG   T   S   +T     PDN 
Sbjct: 167 PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNT 226

Query: 661 GRS----RAKVVSQSQRS--RSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSS 714
             S     +  V  S RS   + +PAG+ +R           +   +   +R  P T +S
Sbjct: 227 TASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTF----HSWPSSKDTRPAPPTTTS 282

Query: 715 EKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLD 774
                   S G     SP+ I     S   R + S      T+  SS  ++    FP  D
Sbjct: 283 AFVEPSTTSHG-----SPSSIPTTHIS--ARSTTSGLVEESTTYHSSPGSTQTMHFPESD 335

Query: 775 -RFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASS 833
              G G+      S     + S  +   A V    ++P      P    +    +S  +S
Sbjct: 336 TTSGRGEESTTSHSSTTHTISSAPSTTSALV----EEPTSYHSSPGSTATTHFPDSSTTS 391

Query: 834 VCSERSYGSRN 844
             SE S  S +
Sbjct: 392 GRSEESTASHS 402



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 7/142 (4%)

Query: 550 PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
           P S  +S  S++S     S   S T + +S  ST S +  STT  +    ++I     ++
Sbjct: 664 PASSTTSGHSEKSTIFHSSPDASGT-TPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 722

Query: 610 AKSKVSSSSGT---TPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAK 666
               +S +S T   +P S    L P S  SLG      +S+ S +   ST      +   
Sbjct: 723 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLG---VGEESTTSRSQPGSTHSTVSPASTT 779

Query: 667 VVSQSQRSRSANPAGAGSRSSS 688
               S+ S +   +  GS  ++
Sbjct: 780 TPGLSEESTTVYSSSRGSTETT 801



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 49/224 (21%), Positives = 84/224 (37%), Gaps = 10/224 (4%)

Query: 553  DRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDI--DVNAAASA 610
            D +++S     + P+ +      +T S A + + +  STT     S  D         SA
Sbjct: 1279 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSA 1338

Query: 611  KSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQ 670
              ++S++S  +P S+       S  +LGR         S    A+TP     + + +V +
Sbjct: 1339 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEE 1398

Query: 671  SQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRET 730
            S    S+  +             G      T  SS    ++      S +   +  S  +
Sbjct: 1399 STAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV-EEPTSYHS 1457

Query: 731  SPNRIGLARSSRIPRPSMSQGCSRD-TSRESSRDTSPARGFPPL 773
            SP  I    ++  P  S + G S + T+  SS DT+   G  PL
Sbjct: 1458 SPGSIA---TTHFPESSTTSGRSEESTASHSSPDTN---GITPL 1495


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 60/233 (25%), Positives = 90/233 (38%), Gaps = 26/233 (11%)

Query: 527  TLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVST 586
            ++ SS  K+  SH  +S S  S     +SS S   S ++  S+  S  GS+ S  S  S+
Sbjct: 1088 SVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSS 1147

Query: 587  KSVSTTGS-------LQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGR 639
            +S    GS       L    S   +       S ++ S      S + + PPG       
Sbjct: 1148 QSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGG------ 1201

Query: 640  IRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGG 699
                  S   A+ +   P     S+AK    S  S  +  +     SSS G    SG G 
Sbjct: 1202 ------SDKLASPMKPVPGTPPSSKAK----SPISSGSGGSHMSGTSSSSGMKSSSGLGS 1251

Query: 700  LTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARS---SRIPRPSMS 749
                S + PP + S    S    S G S  +S N+ G ++    SR  +PS++
Sbjct: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 62/238 (26%), Positives = 91/238 (38%), Gaps = 20/238 (8%)

Query: 538  SHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQR 597
            S   +S S+ S       S SS  S +   S K   + S  S +S +S+   S+ GS   
Sbjct: 1081 SQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGS--- 1137

Query: 598  SRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTP 657
                     + S++SK SS SG  P SS       S  S       +    S  N + + 
Sbjct: 1138 ---------SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSK 1188

Query: 658  DNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKL-LGSGYGG--LTGGSSRGPPVTPSS 714
             N   S ++    S +  S      G+  SS  K  + SG GG  ++G SS     +   
Sbjct: 1189 PNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSS-----SSGM 1243

Query: 715  EKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPP 772
            +  S +  S   S++T P+      SS     S S   S      SS+  SP+R   P
Sbjct: 1244 KSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKP 1301



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 52/207 (25%), Positives = 82/207 (39%), Gaps = 18/207 (8%)

Query: 575  GSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSY 634
            G  +S +   S+ SVS++GS          +++AS   K+ SS   +  SS++ L    Y
Sbjct: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSK--SEGSSSSKLSSSMY 1132

Query: 635  ASLGRIRT--RRQSSGSATNVASTPDNR-----GRSRAKVVSQSQRSRSANPAGAGSRSS 687
            +S G   +   + SS S     S+P  +     G S  K+  Q + S   NP+ +    S
Sbjct: 1133 SSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNIS 1192

Query: 688  SPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRET---------SPNRIGLA 738
                    G   L       P   PSS+ +S I    G S  +         S + +G +
Sbjct: 1193 PSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSS 1252

Query: 739  RSSRIPRPSMSQGCSRDTSRESSRDTS 765
             S     P  S  C+  +S  SS  +S
Sbjct: 1253 GSLSQKTPPSSNSCTASSSSFSSSGSS 1279



 Score = 32.7 bits (73), Expect = 2.8
 Identities = 36/177 (20%), Positives = 59/177 (33%), Gaps = 27/177 (15%)

Query: 699  GLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIP---------RPSMS 749
            G +  +  GP +     KRS+ P + G S++  P R       + P          P  S
Sbjct: 977  GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTS 1036

Query: 750  QGCSRDTSRESSRDTSPARGFPPLDRFGL---------GQP---------GRIPGSVNAM 791
             G S+         T P    PP+ +  +         G+P         G +  S +  
Sbjct: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1096

Query: 792  RVLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIP 848
                +S+   +A      K  +         S    +S  SS  S+    S++GG P
Sbjct: 1097 HHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 54/224 (24%), Positives = 90/224 (40%), Gaps = 9/224 (4%)

Query: 542 NSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD 601
           +SDS  S   SD S SS  +S +   S+  S + S+ S +S  S  S S+  S     SD
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSD---SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748

Query: 602 IDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRG 661
              ++ +S  S  S+SS ++  S ++     S +S     +    S  ++N + + ++  
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 662 RSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP 721
            S +   S S  S S++ + +   S S      S     + GS         S  RS   
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS------DSSNRSDSS 862

Query: 722 RSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTS 765
            S   S  +  +    +  S     S +   S D+S  S  D+S
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS 906



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 57/237 (24%), Positives = 97/237 (40%), Gaps = 6/237 (2%)

Query: 529 ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKS 588
           +SS  K+  S    SDS  S  +SD S S+S +S +   S+  S   S +S +S  S  S
Sbjct: 618 DSSDSKS-DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD-SSNSSNSSDSSDSSDSS 675

Query: 589 VSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSG 648
            S++ S   + SD   ++ +S  S+ S SS ++   S+ +    +  S     +    S 
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSS 735

Query: 649 SATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGP 708
            ++N + + D+   S +   S S  S +++ +   S SS       S     +  SS   
Sbjct: 736 DSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSS 795

Query: 709 PVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTS 765
             + SS+  +    S       S +    + SS     S S   S  +    S D+S
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDS----SNSSDSSNSSDSSDSSNSSDSSDSSDSS 848



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 53/238 (22%), Positives = 91/238 (38%), Gaps = 1/238 (0%)

Query: 529  ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSP-TGSTTSRASTVSTK 587
            ESS          +SDS  S   +   SS S  S +   S+  S  + S+ S  S+ S+ 
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946

Query: 588  SVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSS 647
            S  ++ S   S S    N++ S+ S  S SS ++  S ++     S +S     +    S
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006

Query: 648  GSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRG 707
              +++ + + ++   S +   S S  S  ++ +   S SS       S     +  SS  
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066

Query: 708  PPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTS 765
               + SS+       S+      S N    + SS     S S   S  +    S ++S
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124



 Score = 40.8 bits (94), Expect = 0.010
 Identities = 40/159 (25%), Positives = 67/159 (42%)

Query: 529  ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKS 588
            ESS      +   +SDS  S   SD S SS     +   ++  S   S +S +S  S  S
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142

Query: 589  VSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSG 648
             S+  S     SD   ++ +S  S  S SS ++  S+++     S +S     +    S 
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202

Query: 649  SATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSS 687
             +++ + + D+   S +   S S  S  +N +   S SS
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241



 Score = 37.7 bits (86), Expect = 0.086
 Identities = 53/227 (23%), Positives = 85/227 (37%), Gaps = 3/227 (1%)

Query: 542 NSDSIVSLPQSDRSSS--SSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGS-LQRS 598
           +SDS  S      SSS   S +S +   S   S   S +S +S  S  S S+  S    S
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622

Query: 599 RSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPD 658
           +SD   + + S+ S   S S  +  S ++     S +S     +    S  +++ +S+ D
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682

Query: 659 NRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRS 718
           +   S +   S S  S  ++ +   S S S      S        SS     + SS    
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742

Query: 719 KIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTS 765
               S   +   S +    + SS     S S   S  ++   S D+S
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789



 Score = 35.0 bits (79), Expect = 0.56
 Identities = 41/162 (25%), Positives = 63/162 (38%), Gaps = 19/162 (11%)

Query: 529  ESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKS 588
            ESS          +SDS  S   SD S SS+    +    +  S   S +S +S  S  S
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1208

Query: 589  VSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSG 648
             S+  S     SD   ++ +S  ++ S SS ++  S ++                  SS 
Sbjct: 1209 DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS--------------NSSDSSD 1254

Query: 649  SATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPG 690
            S+ +  ST D+   S         +S + N  G+ S S S G
Sbjct: 1255 SSDSSDSTSDSNDES-----DSQSKSGNGNNNGSDSDSDSEG 1291


>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
          Length = 437

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 54/229 (23%), Positives = 94/229 (41%), Gaps = 14/229 (6%)

Query: 542 NSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD 601
           ++ ++ + P   +    S +S   P + K SP+ S+    +   T + S  G+  +++ D
Sbjct: 36  SAGNVSTHPSLSQRPGGSTKSHPEPQTPKDSPSKSSAEAQTPEDTPNKS--GAEAKTQKD 93

Query: 602 IDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTP-DNR 660
               + A AK++  S+S +   S A      +  S   ++T + S+G +   A TP D+ 
Sbjct: 94  SSNKSGAEAKTQKGSTSKSG--SEAQTTKDSTSKSHPELQTPKDSTGKSGAEAQTPEDSP 151

Query: 661 GRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKI 720
            RS A+  +Q   S S + + A +    P K    G     G S  G       +    +
Sbjct: 152 NRSGAEAKTQKD-SPSKSGSEAQTTKDVPNKSGADGQTPKDGSSKSG----AEDQTPKDV 206

Query: 721 PRSQGCSRET---SPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSP 766
           P   G  ++T     N+ G      I  PS S G    TS++S     P
Sbjct: 207 PNKSGAEKQTPKDGSNKSGAEEQGPIDGPSKS-GAEEQTSKDSPNKVVP 254


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 63/224 (28%), Positives = 97/224 (43%), Gaps = 13/224 (5%)

Query: 556 SSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRS-DIDVNAAASAKSKV 614
           S S   S +R   +++S + S +S++S   ++S S +GS  RS+S     + + S K K 
Sbjct: 188 SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKS 247

Query: 615 SSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRS 674
            S S     S + +       S  +   + Q++ +     S   +R +S++K  S+SQ  
Sbjct: 248 RSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER 307

Query: 675 R-SANPAGAGSRSSSPGKLL---GSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRET 730
           R      G+ SR  S  K L    S      G  SR    + S +KR    RS+  SR  
Sbjct: 308 RVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSR 367

Query: 731 SPNRIGLARS-SRIPRPSMSQGCSR-----DTSRESSRDTSPAR 768
           S +R    RS  R  +     G S+     DT R  SR  SP+R
Sbjct: 368 SRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR--SPSR 409



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 55/222 (24%), Positives = 83/222 (37%), Gaps = 31/222 (13%)

Query: 553 DRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKS 612
           D+  S  + S +R  S  RS + S  SR S   + S  ++ S  RSRS     + + ++S
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234

Query: 613 KVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQ 672
           +  S S                    R +  +  S S     S   + G+SR+K   Q++
Sbjct: 235 RSQSRS--------------------RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAE 274

Query: 673 RSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQG------C 726
                N      +S SP     S +   +   SR        EKR  + R +        
Sbjct: 275 EKIQNNDNVGKPKSRSP-----SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQ 329

Query: 727 SRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPAR 768
           SR  S ++ G    SR    S  +   R  SRE SR  S +R
Sbjct: 330 SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSR 371


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 72/289 (24%), Positives = 109/289 (37%), Gaps = 41/289 (14%)

Query: 515 SHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT 574
           SH  RE    Y T++S  +++   H K SDS     + D S S +    +  LS  RS T
Sbjct: 200 SHRKRETPKSYKTVDSPKRRSRSPHRKWSDS----SKQDDSPSGASYGQDYDLSPSRSHT 255

Query: 575 GS----------TTSRASTVST--KSVSTTGSLQRSRSDI---DVNAAASAKSKVSSSSG 619
            S          +TSR  +VS   K  S   S  RS S       + +  ++ + SS   
Sbjct: 256 SSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYER 315

Query: 620 TTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANP 679
           +  +S  +  P G   S     ++R  S S      +  +R RS A     S  S+    
Sbjct: 316 SGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRS 375

Query: 680 AGAGSRSS-SPGKL-LGSGYGG-----------------LTGGSSRGPPV-TPSSEKRSK 719
           +     SS SP +L L S  G                  + G  S+G PV  P  E  S 
Sbjct: 376 SSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSV 435

Query: 720 IPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPAR 768
             +  G   +  P  + L +S+  P   +      +T  ++S DT   +
Sbjct: 436 EAKDSGLESKKLPRSVKLEKSA--PDTELVNVTHLNTEVKNSSDTGKVK 482


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 72/289 (24%), Positives = 109/289 (37%), Gaps = 41/289 (14%)

Query: 515 SHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPT 574
           SH  RE    Y T++S  +++   H K SDS     + D S S +    +  LS  RS T
Sbjct: 200 SHRKRETPKSYKTVDSPKRRSRSPHRKWSDS----SKQDDSPSGASYGQDYDLSPSRSHT 255

Query: 575 GS----------TTSRASTVST--KSVSTTGSLQRSRSDI---DVNAAASAKSKVSSSSG 619
            S          +TSR  +VS   K  S   S  RS S       + +  ++ + SS   
Sbjct: 256 SSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYER 315

Query: 620 TTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANP 679
           +  +S  +  P G   S     ++R  S S      +  +R RS A     S  S+    
Sbjct: 316 SGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRS 375

Query: 680 AGAGSRSS-SPGKL-LGSGYGG-----------------LTGGSSRGPPV-TPSSEKRSK 719
           +     SS SP +L L S  G                  + G  S+G PV  P  E  S 
Sbjct: 376 SSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSV 435

Query: 720 IPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPAR 768
             +  G   +  P  + L +S+  P   +      +T  ++S DT   +
Sbjct: 436 EAKDSGLESKKLPRSVKLEKSA--PDTELVNVTHLNTEVKNSSDTGKVK 482


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 20/144 (13%)

Query: 554 RSSSSSQESLNRPLSAKRSPTGSTT-----SRASTVSTKSVSTTGSLQRSRSDIDVNAAA 608
           RS S S+ S +R  S   SP+ S +     SR+S+ S++S S + S +RSRS    + ++
Sbjct: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSS-SSQSRSRSSSRERSRSRGSKSRSS 259

Query: 609 SAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVV 668
           S   + SSS     +SS+++ P  +     R R+R +SS S         +R + R +  
Sbjct: 260 SRSHRGSSSPRKRSYSSSSSSPERN-----RKRSRSRSSSSG--------DRKKRRTRSR 306

Query: 669 SQSQRSRSANPAG-AGSRSSSPGK 691
           S  +R RS++ +  +GSRSSS  K
Sbjct: 307 SPERRHRSSSGSSHSGSRSSSKKK 330



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 639 RIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYG 698
           R R++ +SS S ++  S+  +  RSR+       RSRS + + + SRS S  +      G
Sbjct: 201 RSRSKSRSSHSRSSSRSSSPSSSRSRS-------RSRSRSSSSSQSRSRSSSRERSRSRG 253

Query: 699 GLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARS---------SRIP--RPS 747
             +  SSR    + S  KRS    S    R    +R   + S         SR P  R  
Sbjct: 254 SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHR 313

Query: 748 MSQGCSRDTSRESSR 762
            S G S   SR SS+
Sbjct: 314 SSSGSSHSGSRSSSK 328



 Score = 33.1 bits (74), Expect = 2.1
 Identities = 37/108 (34%), Positives = 48/108 (44%), Gaps = 12/108 (11%)

Query: 662 RSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIP 721
           RSR+K  S+S  SRS+      SRSSSP              SS       SS +RS   
Sbjct: 201 RSRSK--SRSSHSRSS------SRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERS--- 249

Query: 722 RSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARG 769
           RS+G S+  S +R     SS   R   S   S + +R+ SR  S + G
Sbjct: 250 RSRG-SKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296



 Score = 31.6 bits (70), Expect = 6.2
 Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 11/139 (7%)

Query: 635 ASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLG 694
           A L +          +    S   +R +SR+     S  SRS++P+ + SRS S  +   
Sbjct: 178 ADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSS--SRSSSPSSSRSRSRSRSRSSS 235

Query: 695 SGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSR 754
           S     +  SSR    +  S+ RS     +G S   SP +   + SS  P  +  +  SR
Sbjct: 236 SSQ-SRSRSSSRERSRSRGSKSRSSSRSHRGSS---SPRKRSYSSSSSSPERNRKRSRSR 291

Query: 755 -----DTSRESSRDTSPAR 768
                D  +  +R  SP R
Sbjct: 292 SSSSGDRKKRRTRSRSPER 310


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 18/184 (9%)

Query: 553 DRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKS 612
           DR SS S++        K+       SR  + S K  S++ S  RS S         AK 
Sbjct: 739 DRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHS--------KAKH 790

Query: 613 KVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQS- 671
            + S+  T   S + +  P   A     R   +S  +A  V+ +P   G SR +  S+S 
Sbjct: 791 SLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSP---GASRKRTRSRSP 847

Query: 672 ------QRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQG 725
                 +RSRS   + A S+S SP K            S+    V+P   + S   RS+G
Sbjct: 848 HEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRG 907

Query: 726 CSRE 729
            S+E
Sbjct: 908 VSQE 911


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 28/234 (11%)

Query: 566 PLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSS 625
           P +A+ SP    +  +S  ST+S S +      R+      + S  S+  S S +  +SS
Sbjct: 378 PSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSS 437

Query: 626 -AAALPPGSYASLGRIRTRRQSSGSATNVASTPD-------------NRGRSRAKVVSQS 671
            +    P S +S    R+RR  S S  + +   D              R R R +  S  
Sbjct: 438 KSGKRSPPSRSS----RSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPM 493

Query: 672 QRSRSANPAGAGSRSSSPGKLLGSGY--------GGLTGGSSRGPPVTPSSEKRS-KIPR 722
           ++ R  +P+   +R  +  +     Y        G L+  SS     +  S  RS    R
Sbjct: 494 RKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSR 553

Query: 723 SQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRF 776
           S+  SR  S  R   + SSR P P  S+  SR  SR  SR  S +R +   D +
Sbjct: 554 SRSRSRRRSRTRTSSSSSSRSPSPG-SRSRSRSRSRSRSRSRSQSRSYSSADSY 606



 Score = 35.8 bits (81), Expect = 0.33
 Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 26/172 (15%)

Query: 518 SREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGST 577
           SRE +  Y   +S  ++  ++  +      S  +  R  S S     R  SA++ P    
Sbjct: 463 SRERDPKYSEKDSQQRERERARRRRRS--YSPMRKRRRDSPSHLEARRITSARKRPI--P 518

Query: 578 TSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASL 637
             R S  S+ S+S+T S   S S               S S +  +S + +       S 
Sbjct: 519 YYRPSPSSSGSLSSTSSWYSSSS---------------SRSASRSYSRSRS------RSR 557

Query: 638 GRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQ-RSRSANPAGAGSRSSS 688
            R R+R ++S S+++ + +P +R RSR++  S+S+ RS+S + + A S SS+
Sbjct: 558 SRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSST 609


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/305 (24%), Positives = 109/305 (35%), Gaps = 35/305 (11%)

Query: 496  HDADSEARIE-ARKCYWGF------------HSHFSREAEHLYHTLESSYQKALQSHLKN 542
            H  DSE R E A + ++G              SH    A H  H+ ESS Q   +    +
Sbjct: 1603 HSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASH-GHSAESSRQSGTRHAETS 1661

Query: 543  SDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVS-TTGSLQRSRSD 601
            S    +  Q    SS  +   +R   +  S T S T R    S    S   GS     SD
Sbjct: 1662 SGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721

Query: 602  IDVNAAASAKSKVSSSSGTTPF-----------SSAAALPPGSYASLGRIRTRRQSSGSA 650
             + ++  S    VS+     P            S   +   GS+  L ++ T  QS  + 
Sbjct: 1722 SEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSF--LYQVSTHEQSESAH 1779

Query: 651  TNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGL------TGGS 704
                 +   R RSR +    S R  SA+  G  +    PG   G   G        + G 
Sbjct: 1780 GRTGPSTGGRQRSRHEQARDSSR-HSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGH 1838

Query: 705  SRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDT 764
            S       +S++RS + R Q  SR  S       +S    R S S+     +  +SSR +
Sbjct: 1839 SGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHS 1898

Query: 765  SPARG 769
               +G
Sbjct: 1899 QVGQG 1903



 Score = 35.4 bits (80), Expect = 0.43
 Identities = 82/346 (23%), Positives = 123/346 (35%), Gaps = 44/346 (12%)

Query: 537  QSHLKNSD--SIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGS 594
            + H + SD  S+    Q      S QES       +   +GS   + ST   +S S  G 
Sbjct: 1075 EGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVST-HEQSESAHGR 1133

Query: 595  LQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVA 654
             + S      +    A+     S+      +  A P       G  R  RQ S    +V 
Sbjct: 1134 TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHP-------GSRRGGRQGSHHEQSVD 1186

Query: 655  STPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVT-PS 713
             +  + G   +   SQ +   S   +G+ S S    K   SG G    GS      +   
Sbjct: 1187 RS-GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWAD 1245

Query: 714  SEKRSKIPRSQGCSRETSPNR-IGLARSSRIPRPS-----MSQGCSRD---TSRESSRDT 764
            S + S++ + Q     TS ++   +++ S   R S     +S   SR+   +SRE SRD 
Sbjct: 1246 SSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDG 1305

Query: 765  SPARGFPPLDRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRRRYEP---YGM 821
            S   GF   DR   G       S ++ R   T     ++   A+    + R  P   +G 
Sbjct: 1306 SRHPGFHQEDRASHGH------SADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGS 1359

Query: 822  YSDDDANSDASSVCSERSYGSRNGGIPHYLRQTEDVAEVLNHCASS 867
                 A+S            SR+ GI H  RQ         H  SS
Sbjct: 1360 RHQQSADS------------SRHSGIGH--RQASSAVRDSGHRGSS 1391



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 73/326 (22%), Positives = 117/326 (35%), Gaps = 44/326 (13%)

Query: 489 ETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLES------SYQKALQSHLKN 542
           E  ++G++D ++  R+  +    G  + +    +  Y T +S       Y+++  S  K+
Sbjct: 208 EDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKS 267

Query: 543 SDSI----------VSLPQS------------DRSSSS-SQESLNRPLSAKRSPTGSTTS 579
           S  +          V L +S            DR S   S++S     SA R+  GS   
Sbjct: 268 SSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWE 327

Query: 580 RASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFS-SAAALPPGSYASLG 638
           ++   S    S            D +  +  +   +SS G T  S   A   PG     G
Sbjct: 328 QSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSG 387

Query: 639 RIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAG---AGSRSSSPGKLLGS 695
             ++   S  SAT        RG++ + V  +  R  S + A      S +S    + G 
Sbjct: 388 HQQSADSSRHSAT-------GRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGH 440

Query: 696 GYGGLTGGSSRGPPVTPSSEK--RSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQGCS 753
           G  GL   S +      S E+  RS     Q  + E   +  G   +S   R       +
Sbjct: 441 GKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQA 500

Query: 754 RDTSRESS--RDTSPARGFPPLDRFG 777
           RD+SR S+        RG P   R G
Sbjct: 501 RDSSRHSASQEGQDTIRGHPGSSRGG 526



 Score = 32.0 bits (71), Expect = 4.7
 Identities = 86/359 (23%), Positives = 132/359 (36%), Gaps = 75/359 (20%)

Query: 514  HSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSP 573
            HS  S      +HT  SS+ +A+ SH +   S       +R  S  Q+S           
Sbjct: 1321 HSADSSRQSGTHHTESSSHGQAVSSHEQARSS-----PGERHGSRHQQS----------- 1364

Query: 574  TGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPPGS 633
              + +SR S +        G  Q S +  D     S+ S+V++S G +  S        S
Sbjct: 1365 --ADSSRHSGI--------GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQ-----S 1409

Query: 634  YASLGRIRTRRQS-SGSATNVASTPDNRGRSRAKVVSQSQRSRSAN----PAGAG----- 683
             ++ G+    +QS   SA   +     R RS    VS  ++S S +    P+  G     
Sbjct: 1410 VSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSR 1469

Query: 684  ---SRSSSPGKLLGSGYGGLTG--GSSRGPPVTPSSEKRSKIPRSQGC----SRETSPNR 734
               +R+SS       G   + G  GSSRG      S     + RS       S  T   R
Sbjct: 1470 HEQARNSSRHSASQDGQDTIRGHPGSSRGG--RQGSYHEQSVDRSGHSGYHHSHTTPQGR 1527

Query: 735  IGLARSSRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFG------LGQPGRIPGSV 788
               +     PR +  Q  + + S + SR  S +R   P  R G      +GQ G   GS 
Sbjct: 1528 SDASHGQSGPRSASRQTRNEEQSGDGSRH-SGSRHHEPSTRAGSSRHSQVGQ-GESAGSK 1585

Query: 789  NAMR---VLSTSTDLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRN 844
             + R    +S   D E    D+ ++            S+  + +   S   +  +GSRN
Sbjct: 1586 TSRRQGSSVSQDRDSEGHSEDSERR------------SESASRNHYGSAREQSRHGSRN 1632



 Score = 31.2 bits (69), Expect = 8.1
 Identities = 62/287 (21%), Positives = 101/287 (35%), Gaps = 21/287 (7%)

Query: 496  HDADSEARIEARKCYWGFHSHFSREA------EHLYHTLESSYQKALQSHLKNSDSIVSL 549
            H  DS+ +  +     G H    +E+      E   H+    YQ +     ++S      
Sbjct: 2698 HSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG- 2756

Query: 550  PQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAAS 609
            P +     S  E          S  G  T R    S++     G  Q    +  V+++  
Sbjct: 2757 PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSR-----GGRQGYHHEHSVDSSGH 2811

Query: 610  AKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQS------SGSATNVASTPDNRGRS 663
            + S  S ++     S A+    GS ++    R   QS      SGS  + AST  +  R 
Sbjct: 2812 SGSHHSHTTSQGR-SDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRH 2870

Query: 664  RAKVVSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKR--SKIP 721
               V  QS+ SR +   G+     S  +         +G +SR    +   + R  S+ P
Sbjct: 2871 SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP 2930

Query: 722  RSQGCSRETSPNRIGLARSSRIPRPSMSQGCSRDTSRESSRDTSPAR 768
            RS    R    +    +R S       S G    +S E +R ++  R
Sbjct: 2931 RSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGER 2977


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 68/281 (24%), Positives = 109/281 (38%), Gaps = 34/281 (12%)

Query: 545 SIVSLPQSDRSSSSSQESLNRPLS---AKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSD 601
           S  SL + D ++S S+      ++   ++ SPTG  ++ + T +    S TGS       
Sbjct: 318 SRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGS------- 370

Query: 602 IDVNAAASAKSKVSSSSGTTPFSSAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRG 661
               A+ +  S  +S +GT P +S    P  S ASL R   R   +G  +  + T  +  
Sbjct: 371 -PSTASLTGLSSTASPTGTPPRASPTGTP--STASLTRKPPRASPTGMLSRTSITKMDST 427

Query: 662 RSRAKV---VSQSQRSRSANPAGAGSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRS 718
            S  +     S +     A+P G  SR+S  G             S+  P  +PS+   +
Sbjct: 428 ASPTRTPPRASPTGTPPRASPTGTPSRASPTGT-----------QSTASPTGSPSTASPT 476

Query: 719 KIPRSQGCSRETSPNRIGLARS-SRIPRPSMSQGCS-RDTSRESSRDTSPARGFP---PL 773
             P +   S   SP+R  L R+ SR     M    S   T   +S   +P+   P   P 
Sbjct: 477 GSPST--ASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPS 534

Query: 774 DRFGLGQPGRIPGSVNAMRVLSTSTDLEAAVADALKKPVRR 814
               +G P R   +    R   T T   A++    +  + R
Sbjct: 535 TALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTR 575



 Score = 39.7 bits (91), Expect = 0.023
 Identities = 51/204 (25%), Positives = 82/204 (40%), Gaps = 30/204 (14%)

Query: 572 SPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAALPP 631
           SPTGS ++ + T S  + S TGS  R+      + A+  K + ++S   TP  ++    P
Sbjct: 465 SPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTP 524

Query: 632 GSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSSPGK 691
            + +  G   T   + GS +  A T   R  SRA +     R+    P+ A S + +P  
Sbjct: 525 STASPTGSPST-ALAMGSPSRAALT---RTPSRASLTRTPSRASLTTPSRA-SLTRTPST 579

Query: 692 LLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRPSMSQG 751
           +L           +R PP    +          G    TSP   G+  S+ + +   +  
Sbjct: 580 VL----------LTRMPPSASPT----------GMPSRTSPT--GMPSSALLTKMDSTAS 617

Query: 752 CSRDTSRESSRDTSP---ARGFPP 772
            +R   R S  +T P     G PP
Sbjct: 618 ITRTPPRASPTETPPRASPTGTPP 641



 Score = 36.6 bits (83), Expect = 0.19
 Identities = 40/147 (27%), Positives = 61/147 (41%), Gaps = 23/147 (15%)

Query: 550 PQSDRSSSSSQESLNRPLSAKRSPTG-----STTSRASTVSTKSVSTTGSLQRSRSDIDV 604
           P++  + + S  SL R    + SPTG     S T   ST S   + +T S+ R+ S    
Sbjct: 162 PRASLTMTPSTASLTRT-PPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSR--- 217

Query: 605 NAAASAKSKVSSSSGTTPFSSAAALPPGSYASL---GRIRTRRQSSGSATNVAS-TPDNR 660
                     +S +GT P +S    PP +  S+     +  R     S T + S T   +
Sbjct: 218 ----------ASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTK 267

Query: 661 GRSRAKVVSQSQRSRSANPAGAGSRSS 687
             S A +     R  +A+P G  SR+S
Sbjct: 268 MDSTASITRTPSRPSTASPTGTPSRAS 294



 Score = 32.3 bits (72), Expect = 3.6
 Identities = 53/215 (24%), Positives = 75/215 (34%), Gaps = 26/215 (12%)

Query: 1055 TPEFTMLLGALPKTFQDGA-TKLLHNHLKNSSNTSVGSPSNTIGRTPSRH---------- 1103
            TP    L+  LP+    G  ++     + ++++ S   P  +I RTPSR           
Sbjct: 298  TPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTAS 357

Query: 1104 ---TSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPPPFSQPNSIPTAPSHKALRRS 1160
               T SR SP  SP+  S  GLS +     S  G     PP + P   P+  S       
Sbjct: 358  PTGTPSRASPTGSPSTASLTGLSSTA----SPTG----TPPRASPTGTPSTASLTRKPPR 409

Query: 1161 YSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPIKRDGKKECDIVSRDGG 1220
             SP+ +   T     +   S  R    A    +         P +          S  G 
Sbjct: 410  ASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTG- 468

Query: 1221 AASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRA 1255
              SP+T    GS      T   ++ SL  T P RA
Sbjct: 469  --SPSTASPTGSPSTASPTGSPSRASLTRT-PSRA 500


>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
           2 [Homo sapiens]
          Length = 1214

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 63/264 (23%), Positives = 93/264 (35%), Gaps = 47/264 (17%)

Query: 514 HSHFSREAEHLYHTLESSYQKAL-----QSHLKNSDSIVSLPQSDRSSSSSQESLNRPLS 568
           HS    EA H  HT +++ ++ L     Q HL   + +  L +     ++S++S+ R   
Sbjct: 751 HSLAGDEATH--HTEDAAEEERLVLLENQKHLPVEEQLKLLLERLDEVNASKQSVGRSRR 808

Query: 569 AKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFSSAAA 628
           AK      T  R      +     G  +   S               S    TP  +A  
Sbjct: 809 AKMIKKEMTALRRKLAHQRETGRDGPERHGPS---------------SRGSLTPHPAACD 853

Query: 629 LPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGAGSRSSS 688
               + ++     ++  S G   N++STP +    R  V+   +  ++A P     R   
Sbjct: 854 KDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNPKTAGPP---KRPGR 910

Query: 689 PGKLLGSGYGGLTGGSSRGPPVTP--SSEKRSKIPRSQGCSRETSPNRIGLARSSRIPRP 746
           P K   S      GGS  GPP  P  SS ++ K  RS                    PRP
Sbjct: 911 PPKNRESQMTPSHGGSPVGPPQLPIMSSLRQRKRGRS--------------------PRP 950

Query: 747 SMSQGCSRDTSRESSRDTSPARGF 770
           S S     D S E      PA GF
Sbjct: 951 SSSSDSDSDKSTEDPPMDLPANGF 974


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,400,379
Number of Sequences: 37866
Number of extensions: 2560563
Number of successful extensions: 12548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 440
Number of HSP's that attempted gapping in prelim test: 10123
Number of HSP's gapped (non-prelim): 2224
length of query: 1538
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1423
effective length of database: 13,892,928
effective search space: 19769636544
effective search space used: 19769636544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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