Search of human proteins with 31559815

Search of human proteins with 31559815

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31559815 keratin 26 [Homo sapiens]
         (468 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31559815 keratin 26 [Homo sapiens]                                 926   0.0  
gi|153945736 keratin 27 [Homo sapiens]                                635   0.0  
gi|31559829 keratin 25 [Homo sapiens]                                 610   e-174
gi|114431246 keratin 25D [Homo sapiens]                               608   e-174
gi|192807292 keratin 24 [Homo sapiens]                                418   e-117
gi|195972866 keratin 10 [Homo sapiens]                                416   e-116
gi|4557699 keratin 12 [Homo sapiens]                                  395   e-110
gi|24430192 keratin 16 [Homo sapiens]                                 386   e-107
gi|15431310 keratin 14 [Homo sapiens]                                 378   e-105
gi|24430190 keratin 15 [Homo sapiens]                                 376   e-104
gi|131412228 keratin 13 isoform b [Homo sapiens]                      367   e-102
gi|131412225 keratin 13 isoform a [Homo sapiens]                      367   e-101
gi|4557701 keratin 17 [Homo sapiens]                                  365   e-101
gi|24234699 keratin 19 [Homo sapiens]                                 348   5e-96
gi|55956899 keratin 9 [Homo sapiens]                                  317   1e-86
gi|4504927 keratin 36 [Homo sapiens]                                  298   7e-81
gi|27894337 keratin 20 [Homo sapiens]                                 290   1e-78
gi|94538345 keratin 35 [Homo sapiens]                                 286   2e-77
gi|116488398 keratin 32 [Homo sapiens]                                271   1e-72
gi|27894339 keratin 23 [Homo sapiens]                                 269   5e-72
gi|14917117 keratin 33A [Homo sapiens]                                267   1e-71
gi|14917115 keratin 31 [Homo sapiens]                                 267   2e-71
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  263   3e-70
gi|10337581 type I hair keratin 3B [Homo sapiens]                     263   3e-70
gi|40354195 keratin 18 [Homo sapiens]                                 259   5e-69
gi|4557888 keratin 18 [Homo sapiens]                                  259   5e-69
gi|14917119 keratin 34 [Homo sapiens]                                 258   1e-68
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  248   6e-66
gi|55770882 keratin 37 [Homo sapiens]                                 242   5e-64
gi|15431318 keratin 38 [Homo sapiens]                                 239   5e-63

>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  926 bits (2394), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 1   MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSG 60
           MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSG
Sbjct: 1   MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSG 60

Query: 61  GGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYE 120
           GGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYE
Sbjct: 61  GGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYE 120

Query: 121 KCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180
           KCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL
Sbjct: 121 KCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180

Query: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240
           ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV
Sbjct: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240

Query: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300
           NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR
Sbjct: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300

Query: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360
           NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR
Sbjct: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360

Query: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDS 420
           TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDS
Sbjct: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDS 420

Query: 421 TEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP 468
           TEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP
Sbjct: 421 TEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPSKAP 468


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  635 bits (1638), Expect = 0.0
 Identities = 339/469 (72%), Positives = 374/469 (79%), Gaps = 14/469 (2%)

Query: 1   MSFRLSGGSRRI--CSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCN 58
           MS R S  SRR+  C  TGS RLS GG GF AGN C   G  S FSC   G SS G +  
Sbjct: 1   MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGY-- 58

Query: 59  SGGGLGSGA--CAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIK 116
            GGGLG G+  CA F GNEH LLSGNEKVTMQNLNDRLASYL++V ALEEANADLEQKIK
Sbjct: 59  -GGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIK 117

Query: 117 GRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKY 176
           G YEK  PGS R  DHDYSRYF +I++LK QI SAT  NA +VLQNDNARLTADDFRLK+
Sbjct: 118 GWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKF 177

Query: 177 ENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTA 236
           ENELALH SVEAD +GLRRVLDELTLC TDLEIQ ETLSEEL YLKK+HEEEM+ LQ  A
Sbjct: 178 ENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAA 237

Query: 237 GGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAA 296
           GGNVNVEMNA PGVDLTVLLNNMRAEYE LAEQNR+DAEAWFNE+SA+LQQQISD  GA 
Sbjct: 238 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGAT 297

Query: 297 TAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQL 356
           T+ARNEL E+KR LQTLEIELQSL+A KHS ECSL ETE NYC QL QIQ QIG +EEQL
Sbjct: 298 TSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 357

Query: 357 QQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQ 416
            Q+RTETEGQKLEYEQLLD+K+ LEKEI+ YC L+DGE+     +C KSKGY     GNQ
Sbjct: 358 HQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED----GSCSKSKGYG--GPGNQ 411

Query: 417 AKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVPS 465
            KDS++ TIVKTVVEE+D  G +LS RVH+VEEKS+K++N   EQRV S
Sbjct: 412 TKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKSTKVNNKN-EQRVSS 459


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  610 bits (1572), Expect = e-174
 Identities = 323/453 (71%), Positives = 359/453 (79%), Gaps = 8/453 (1%)

Query: 1   MSFRLSGGSRRICSR--TGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCN 58
           MS RLS  SRR C R  TGS RL GGGT F  GN C  SG  S FS    G SSGG   N
Sbjct: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGG---N 57

Query: 59  SGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGR 118
           +GGG     CAGF  NE  LLSGNEKVTMQNLNDRLASYLD VHALEEANADLEQKIKG 
Sbjct: 58  TGGG---NPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGW 114

Query: 119 YEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYEN 178
           YEK  PGS R  DHDYSRYF +I+DLK QI ++T  NA+ VLQ DNARLTADDFRLKYEN
Sbjct: 115 YEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYEN 174

Query: 179 ELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGG 238
           ELALH SVEAD +GLRRVLDE+TLC TDLEIQ ETLSEE+TYLKK+H+EEM+VLQ  AGG
Sbjct: 175 ELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGG 234

Query: 239 NVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATA 298
           NVNVEMNA PGVDLTVLLNNMRAEYE LAEQNR+DAEAWFNE+SA+LQQQIS+  GA T+
Sbjct: 235 NVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTS 294

Query: 299 ARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQ 358
           ARNELTE+KR LQTLEIELQSL+A KHS ECSL ETE NYC QL QIQ QIG +EEQL Q
Sbjct: 295 ARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQ 354

Query: 359 IRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK 418
           +RTETEGQKLEYEQLLD+K+ LEKEI+ YC L+ G++   KS  YKSK Y   N G+Q K
Sbjct: 355 VRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK 414

Query: 419 DSTEETIVKTVVEELDQIGNLLSLRVHSVEEKS 451
           D  +  +VK V+EE+DQ   +L+ R+HS+EEKS
Sbjct: 415 DPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  608 bits (1569), Expect = e-174
 Identities = 316/467 (67%), Positives = 368/467 (78%), Gaps = 7/467 (1%)

Query: 1   MSFRLSGGSRRICSRTGSG--RLSGGGTGFVAGNVCVGSGARSSFSCTLEG-ISSGGSFC 57
           MS + S GSR +C R+G+G  R   GG GF   + C GS A S FSC L G + S     
Sbjct: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60

Query: 58  NSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKG 117
           ++GG LG+ AC GF G+E  LLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG
Sbjct: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120

Query: 118 RYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYE 177
            YEK  PGS R  DHDYSRY   IEDLK +I S+T  NA+++LQ DNARL ADDFRLKYE
Sbjct: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180

Query: 178 NELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAG 237
           NEL LH +VEAD +GLRRVLDELTLC TD E+Q E+LSEE+TYLKK+HEEEM+ LQ  AG
Sbjct: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240

Query: 238 GNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAAT 297
           GNVNVEMNA PGVDL VLLNNMRAEYE LAEQNRKDAEAWFNE+SA+LQQQIS   GAAT
Sbjct: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300

Query: 298 AARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQ 357
            AR++LTE++R LQTLEI+LQSLMA KHS ECSL ETE NYC QL QIQ QIG +EEQL 
Sbjct: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360

Query: 358 QIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQA 417
           Q+RTETEGQKLEYE LLDVK+ LEKEI+ YC L+DG+     ++C KSKG+   + GN +
Sbjct: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGD----GNSCSKSKGFGSGSPGNSS 416

Query: 418 KDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSKISNITVEQRVP 464
           KD ++ T+VKTVVEELDQ G +LS R+HS+EEK+SK++N   EQRVP
Sbjct: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKTSKMTNGKTEQRVP 463


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  418 bits (1075), Expect = e-117
 Identities = 248/468 (52%), Positives = 309/468 (66%), Gaps = 28/468 (5%)

Query: 7   GGSRRICSRTGS-GRLSGGGTGFVAGNVCVG-SG-ARSSFSCTLEGISSG--GSFCNSGG 61
           GG    CS  G  G  SG GTGF  G+   G SG  R S  C     SSG  G F + GG
Sbjct: 65  GGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGG 124

Query: 62  GLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121
           G+G G   G       L SG EK TMQNLNDRLA+YLD V ALEEAN DLE KIK  Y+K
Sbjct: 125 GMGGGVGDG------GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDK 178

Query: 122 CEPGSSREHD-HDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180
             PGS       DYS+Y+S+IEDL+ QI +AT+ NA I+L  DNARL ADDFRLKYENEL
Sbjct: 179 YGPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENEL 238

Query: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240
            L  SVEAD +GLR+VLD+LT+  +DLE+Q E+ +EEL YL+K+HEEEM+ +Q ++GG V
Sbjct: 239 CLRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEV 298

Query: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300
            VEMNA PG DLT LLN+MRA+YE+LAEQNR++AE  FN++SA+LQ QIS   GAAT+A+
Sbjct: 299 TVEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAK 358

Query: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360
           NE+TELKR LQ LEIELQS +A+K S E +LA+TE  Y  QL +IQ QI  +EE++ QI 
Sbjct: 359 NEITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIW 418

Query: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGN----- 415
            ET+ Q  EY+QLLD+K  LE EI+ Y  LLDGE   S    +  +    VN G+     
Sbjct: 419 GETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVS 478

Query: 416 ----------QAKDSTEETIVKTVVEELDQIGNLLSLRVHSVEEKSSK 453
                     Q +DS++  + KT+VEEL   G ++S +V S+ E   K
Sbjct: 479 GDSRSGSCSGQGRDSSKTRVTKTIVEELVD-GKVVSSQVSSISEVKVK 525


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  416 bits (1070), Expect = e-116
 Identities = 240/406 (59%), Positives = 281/406 (69%), Gaps = 19/406 (4%)

Query: 6   SGGSRRICSRTGS--GRLSGG--GTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNS-- 59
           SGGS    S  G   G  SGG  G G   G    GS   SSF  +  G   GGSF     
Sbjct: 53  SGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSF 112

Query: 60  -----------GGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEAN 108
                      GGG G G   GF G +  LLSGNEKVTMQNLNDRLASYLD V ALEE+N
Sbjct: 113 GGGSFGGGGFGGGGFGGGFGGGF-GGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESN 171

Query: 109 ADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLT 168
            +LE KIK  YEK    S +    DYS+Y+  I+DLK QI + T  NA+I+LQ DNARL 
Sbjct: 172 YELEGKIKEWYEK-HGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLA 230

Query: 169 ADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEE 228
           ADDFRLKYENE+AL  SVEAD +GLRRVLDELTL   DLE+Q E+L+EEL YLKK+HEEE
Sbjct: 231 ADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEE 290

Query: 229 MEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQ 288
           M+ L+  + G+VNVEMNA PGVDLT LLNNMR++YE LAEQNRKDAEAWFNE+S  L  +
Sbjct: 291 MKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTE 350

Query: 289 ISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQ 348
           I ++    ++ ++E+TEL+RN+Q LEIELQS +A+K S E SLAETEG YC QL QIQ Q
Sbjct: 351 IDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQ 410

Query: 349 IGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGE 394
           I  +EEQLQQIR ETE Q  EY+QLLD+KI LE EI  Y +LL+GE
Sbjct: 411 ISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456



 Score = 32.3 bits (72), Expect = 0.95
 Identities = 21/54 (38%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 17  GSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
           G G   GGG G   G+   G G  SS   +  G   GG   +SGGG G G+  G
Sbjct: 455 GEGSSGGGGRG--GGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGG 506



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 11/80 (13%)

Query: 1  MSFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTL-----EGISSGGS 55
          MS R S       SR+G G    GG G   G   V S   SS   +L      G  SGGS
Sbjct: 1  MSVRYSSSKHYSSSRSGGG----GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56

Query: 56 FC--NSGGGLGSGACAGFLG 73
          F   +SGGG   G+  G+ G
Sbjct: 57 FSRGSSGGGCFGGSSGGYGG 76



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 17  GSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
           G G  SGG  G  +G    G G+         G SSGG   +SGGG G G+ +G
Sbjct: 514 GGGSSSGGHGGSSSGGY--GGGSSGGGGGGYGGGSSGGG-SSSGGGYGGGSSSG 564



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 7/74 (9%)

Query: 6   SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSF--CNSGGGL 63
           SGG  R     G G   GG  G  +G    G G       +  G   GGS    +SGGG 
Sbjct: 459 SGGGGR-----GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513

Query: 64  GSGACAGFLGNEHS 77
           G G+ +G  G   S
Sbjct: 514 GGGSSSGGHGGSSS 527



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 7   GGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSG 66
           GGS       G G  SGGG G   G+    SG  SS      G SSGG   +S GG G G
Sbjct: 480 GGSSGGGHGGGHGGSSGGGYG--GGS----SGGGSSGGGYGGGSSSGGHGGSSSGGYGGG 533

Query: 67  ACAG 70
           +  G
Sbjct: 534 SSGG 537



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 8/56 (14%)

Query: 17  GSGRLSGG--GTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
           G G   GG  G G+  G+   G G  SS      G   GGS    GGG G G+  G
Sbjct: 500 GGGSSGGGSSGGGYGGGSSSGGHGGSSS------GGYGGGSSGGGGGGYGGGSSGG 549


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  395 bits (1016), Expect = e-110
 Identities = 223/446 (50%), Positives = 299/446 (67%), Gaps = 10/446 (2%)

Query: 7   GGSRRICSRTGSGRLSGGGTGF-VAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGS 65
           GG     S  GS    GGG+G  +AG +  G G        L G S GG     GG  G 
Sbjct: 54  GGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR------ALGGGSFGGLGMGFGGSPGG 107

Query: 66  GACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPG 125
           G+     GN+  LLSG+EK TMQNLNDRLASYLD V ALEEAN +LE KI+  YE    G
Sbjct: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167

Query: 126 SSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHS 185
           ++     DYS+Y+ +IEDL+ +I SA+I NA ++LQ DNARL A+DFR+KYENELAL   
Sbjct: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227

Query: 186 VEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMN 245
           VEAD +GLRRVLDELTL  TDLE+Q E+L+EEL Y+KK+HE+E++  +    G V+VEM+
Sbjct: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287

Query: 246 ATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTE 305
           A PGVDLT LLN+MRA+YE +AEQNRKDAEAWF E+S  L+++IS +     ++++E+T+
Sbjct: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347

Query: 306 LKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEG 365
           L+R  Q LEIELQS +A+K S E SLAE EG+YC QL Q+Q  I  +E QL Q+R + E 
Sbjct: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407

Query: 366 QKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKS--KSTCYKSKGYRPVNSGNQAKDSTEE 423
           Q +++++LL+VK  LE EI+ Y  LLDGE +    + + + +       S + +KD T+ 
Sbjct: 408 QNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKT 467

Query: 424 TIVKTVVEELDQIGNLLSLRVHSVEE 449
             +KTVV+E+   G ++S +V  +EE
Sbjct: 468 RKIKTVVQEMVN-GEVVSSQVQEIEE 492


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  386 bits (992), Expect = e-107
 Identities = 220/409 (53%), Positives = 272/409 (66%), Gaps = 10/409 (2%)

Query: 5   LSGGSRRICSRTGSG-----RLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNS 59
           L+GGS R  S  G G     R S GG   + G    G  + SSF     G   GG     
Sbjct: 35  LAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGF 94

Query: 60  GGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRY 119
           GGGLG+G   GF G +  LL G+EKVTMQNLNDRLASYLD V ALEEANADLE KI+  Y
Sbjct: 95  GGGLGAGFGGGFAGGD-GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWY 153

Query: 120 EKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENE 179
           ++  P   +    DYS YF  IEDL+ +I +ATI NA  +LQ DNARL ADDFR KYE+E
Sbjct: 154 QRQRPSEIK----DYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHE 209

Query: 180 LALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGN 239
           LAL  +VEAD +GLRRVLDELTL  TDLE+Q E L EEL YL+K+HEEEM  L+   GG+
Sbjct: 210 LALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD 269

Query: 240 VNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAA 299
           VNVEM+A PGVDL+ +LN MR +YE +AE+NR+DAE WF  ++  L ++++ +     ++
Sbjct: 270 VNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSS 329

Query: 300 RNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQI 359
           R+E+TEL+R LQ LEIELQS +++K S E SL ET+G YC QL QIQ  IG +EEQL Q+
Sbjct: 330 RSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQL 389

Query: 360 RTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGY 408
           R E E Q  EY+ LLDVK  LE+EI  Y  LL+GE+    S     + Y
Sbjct: 390 RCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSY 438


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  378 bits (971), Expect = e-105
 Identities = 217/408 (53%), Positives = 272/408 (66%), Gaps = 16/408 (3%)

Query: 5   LSGGSRRICSRTGSG------RLSGGGTGFVAGNVCVG-SGARSSFSCTLEGISSGGSFC 57
           L+GGS R  S  G G      R S GG   + G    G S + SSF     G   GG   
Sbjct: 35  LAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGL-- 92

Query: 58  NSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKG 117
             G GLG G   GF G +  LL G+EKVTMQNLNDRLASYLD V ALEEANADLE KI+ 
Sbjct: 93  --GAGLGGGFGGGFAGGD-GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRD 149

Query: 118 RYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYE 177
            Y++  P   +    DYS YF  IEDL+ +I +AT+ NA+++LQ DNARL ADDFR KYE
Sbjct: 150 WYQRQRPAEIK----DYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYE 205

Query: 178 NELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAG 237
            EL L  SVEAD +GLRRVLDELTL   DLE+Q E+L EEL YLKK+HEEEM  L+   G
Sbjct: 206 TELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVG 265

Query: 238 GNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAAT 297
           G+VNVEM+A PGVDL+ +LN MR +YE +AE+NRKDAE WF  ++  L ++++ +     
Sbjct: 266 GDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQ 325

Query: 298 AARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQ 357
           + ++E++EL+R +Q LEIELQS +++K S E SL ET+G YC QL QIQ+ IG +EEQL 
Sbjct: 326 SGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLA 385

Query: 358 QIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKS 405
           Q+R E E Q  EY+ LLDVK  LE+EI  Y  LL+GE+    S+ + S
Sbjct: 386 QLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  376 bits (966), Expect = e-104
 Identities = 218/427 (51%), Positives = 275/427 (64%), Gaps = 22/427 (5%)

Query: 7   GGSRRICSRTGSGRLSGGGTGFVAG-NVC-VGSGARSSFSCTLEGISSGGSFCNSGGGLG 64
           GGSR I + +     SG G G+  G  VC  G GA S F         GG F   GGG+G
Sbjct: 39  GGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVF---------GGGF---GGGVG 86

Query: 65  SGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEP 124
            G   GF G +  LLSGNEK+TMQNLNDRLASYLD V ALEEANADLE KI   Y+K  P
Sbjct: 87  GGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTP 146

Query: 125 GSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHH 184
            S    + DYS+YF  IE+L+ +I + TI N+ ++L+ DNARL ADDFRLKYENELAL  
Sbjct: 147 TSP---ECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQ 203

Query: 185 SVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEM 244
            VEAD +GLRRVLDELTL  TDLE+Q E L+EEL YLKK+HEEEM+       G VNVEM
Sbjct: 204 GVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEM 263

Query: 245 NATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELT 304
           +A PGVDLT +L  MR +YE +AE+NR+D EAWF  ++  L ++++ +      ++ E+T
Sbjct: 264 DAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEIT 323

Query: 305 ELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETE 364
           +L+R +Q LEIELQS +++K   E SLAETE  Y  QLQQIQ  IG +E QL ++R E E
Sbjct: 324 DLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEME 383

Query: 365 GQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEET 424
            Q  EY+ LLD+K  LE+EI  Y +LL+G++ K         G R  +SG     S    
Sbjct: 384 AQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI-----GIREASSGGGGSSSNFHI 438

Query: 425 IVKTVVE 431
            V+  V+
Sbjct: 439 NVEESVD 445


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  367 bits (943), Expect = e-102
 Identities = 207/398 (52%), Positives = 267/398 (67%), Gaps = 9/398 (2%)

Query: 7   GGSRRICSRTGSGRLSGGGTGFVAGNVCVG--SGARSSFSCTLEGISSGGSFCNSGGGLG 64
           GG R + S   +  +SGG  G   G V  G   GA S F     G   GG     GGG G
Sbjct: 24  GGGRGV-STCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFG 82

Query: 65  SGACAGFL---GNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121
            G   GF+     +  LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+  + K
Sbjct: 83  GGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLK 142

Query: 122 CEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELA 181
             P S    + DYS Y+  IE+L+ +I +ATI N  ++L+ DNARL ADDFRLKYENELA
Sbjct: 143 QSPASP---ERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199

Query: 182 LHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVN 241
           L  SVEAD +GLRRVLDELTL  TDLE+Q E+L+EEL Y+KK+HEEEM+       G VN
Sbjct: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVN 259

Query: 242 VEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301
           VEM+ATPG+DLT +L  MR +YE +AE+NR+DAE WF+ +SA L +++S +      ++ 
Sbjct: 260 VEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKT 319

Query: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRT 361
           E+TEL+R LQ LEIELQS +++K   E ++AETE  Y  QLQQIQ  I  +E QL ++R+
Sbjct: 320 EITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRS 379

Query: 362 ETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSK 399
           E E Q  EY+ LLD+K  LE+EI  Y +LL+G++ K +
Sbjct: 380 EMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKKR 417


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  367 bits (941), Expect = e-101
 Identities = 207/396 (52%), Positives = 266/396 (67%), Gaps = 9/396 (2%)

Query: 7   GGSRRICSRTGSGRLSGGGTGFVAGNVCVG--SGARSSFSCTLEGISSGGSFCNSGGGLG 64
           GG R + S   +  +SGG  G   G V  G   GA S F     G   GG     GGG G
Sbjct: 24  GGGRGV-STCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFG 82

Query: 65  SGACAGFL---GNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121
            G   GF+     +  LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+  + K
Sbjct: 83  GGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLK 142

Query: 122 CEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELA 181
             P S    + DYS Y+  IE+L+ +I +ATI N  ++L+ DNARL ADDFRLKYENELA
Sbjct: 143 QSPASP---ERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199

Query: 182 LHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVN 241
           L  SVEAD +GLRRVLDELTL  TDLE+Q E+L+EEL Y+KK+HEEEM+       G VN
Sbjct: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVN 259

Query: 242 VEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301
           VEM+ATPG+DLT +L  MR +YE +AE+NR+DAE WF+ +SA L +++S +      ++ 
Sbjct: 260 VEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKT 319

Query: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRT 361
           E+TEL+R LQ LEIELQS +++K   E ++AETE  Y  QLQQIQ  I  +E QL ++R+
Sbjct: 320 EITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRS 379

Query: 362 ETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
           E E Q  EY+ LLD+K  LE+EI  Y +LL+G++ K
Sbjct: 380 EMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  365 bits (936), Expect = e-101
 Identities = 221/440 (50%), Positives = 282/440 (64%), Gaps = 36/440 (8%)

Query: 5   LSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFC-NSGGGL 63
           L GGS R      S RLSGG     AG+  +GS        TL G S    +   SGGG 
Sbjct: 20  LGGGSSRT-----SCRLSGG---LGAGSCRLGSAG--GLGSTLGGSSYSSCYSFGSGGGY 69

Query: 64  GSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCE 123
           GS       G    LL+G EK TMQNLNDRLASYLD V ALEEAN +LE KI+  Y++  
Sbjct: 70  GSS-----FGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124

Query: 124 PGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALH 183
           PG +R    DYS+Y+  IE+L+ +I +AT+ NA+I+LQ DNARL ADDFR K+E E AL 
Sbjct: 125 PGPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180

Query: 184 HSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVE 243
            SVEAD +GLRRVLDELTL   DLE+Q E L EEL YLKK+HEEEM  L+   GG +NVE
Sbjct: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240

Query: 244 MNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNEL 303
           M+A PGVDL+ +LN MR +YE +AE+NRKDAE WF  ++  L ++++ +     + ++E+
Sbjct: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300

Query: 304 TELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTET 363
           +EL+R +Q LEIELQS +++K S E +LAETE  YC QL QIQ  IG +EEQL Q+R E 
Sbjct: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360

Query: 364 EGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEE 423
           E Q  EY+ LLDVK  LE+EI  Y  LL+GE+  +  T YK             K+    
Sbjct: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGED--AHLTQYK-------------KEPVTT 405

Query: 424 TIVKTVVEELDQIGNLLSLR 443
             V+T+VEE+ Q G ++S R
Sbjct: 406 RQVRTIVEEV-QDGKVISSR 424


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  348 bits (894), Expect = 5e-96
 Identities = 196/394 (49%), Positives = 257/394 (65%), Gaps = 10/394 (2%)

Query: 2   SFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGG 61
           S+R S  +       G     G G  F A ++  GSG R         +SS     +S  
Sbjct: 5   SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGV------SVSSARFVSSSSS 58

Query: 62  GLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121
           G   G   G L     LL+GNEK+TMQNLNDRLASYLD V ALE AN +LE KI+  Y+K
Sbjct: 59  GAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQK 118

Query: 122 CEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELA 181
             PG SR    DYS Y++ I+DL+ +I  ATI N+ IVLQ DNARL ADDFR K+E E A
Sbjct: 119 QGPGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQA 174

Query: 182 LHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVN 241
           L  SVEAD +GLRRVLDELTL  TDLE+Q E L EEL YLKK+HEEE+  L+   GG V+
Sbjct: 175 LRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVS 234

Query: 242 VEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301
           VE+++ PG DL  +L++MR++YE +AEQNRKDAEAWF  R+  L ++++ H      +R+
Sbjct: 235 VEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRS 294

Query: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRT 361
           E+T+L+R LQ LEIELQS +++K + E +LAETE  +  QL  IQ  I  +E QL  +R 
Sbjct: 295 EVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRA 354

Query: 362 ETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEE 395
           ++E Q  EY++L+D+K  LE+EI  Y +LL+G+E
Sbjct: 355 DSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  317 bits (813), Expect = 1e-86
 Identities = 186/417 (44%), Positives = 249/417 (59%), Gaps = 25/417 (5%)

Query: 7   GGSRRICSRTGSGRLS-----GGGTGFVAGNVC--VGSGARSSFSCTLEGISSGGSFCN- 58
           GGS R+C R G G        G G GF A ++    G G+R     +  G SS G F   
Sbjct: 55  GGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGG 114

Query: 59  ----SGGGLGSGACAGFLG----------NEHSLLSGNEKVTMQNLNDRLASYLDHVHAL 104
               SGGG G G  +GF G           +  +L+ NEK TMQ LN RLASYLD V AL
Sbjct: 115 FGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQAL 174

Query: 105 EEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDN 164
           EEAN DLE KI+  Y+K  P + +++   YS Y++ I+DLK QI   T+ N   +L  DN
Sbjct: 175 EEANNDLENKIQDWYDKKGPAAIQKN---YSPYYNTIDDLKDQIVDLTVGNNKTLLDIDN 231

Query: 165 ARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKS 224
            R+T DDFR+K+E E  L   V+AD +GLR+VLD LT+  +DLE+Q ETL EEL  LKK+
Sbjct: 232 TRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKN 291

Query: 225 HEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSAT 284
           H+EEM  L     G+VNVE+N  PG DLT  LN+MR EYE L  +NRKD E  +  +   
Sbjct: 292 HKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQ 351

Query: 285 LQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQ 344
           ++ ++S       ++  E+T+L+  +Q LEIELQS ++ K + E SL +T+  YC QLQ 
Sbjct: 352 IEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQM 411

Query: 345 IQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKST 401
           IQ+QI  +E Q+  +R E E Q  EY  LL +K+ LEKEI+ Y NLL+G +   +S+
Sbjct: 412 IQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQEDFESS 468



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 26/58 (44%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 14  SRTGSGRLSGGGTGFVAGNVC-VGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAG 70
           SR GSG   GGG+G   G+    G G+    S    G  SGGS  N GGG GSG  +G
Sbjct: 512 SRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSG 569



 Score = 35.8 bits (81), Expect = 0.086
 Identities = 31/79 (39%), Positives = 33/79 (41%), Gaps = 4/79 (5%)

Query: 6   SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISS--GGSFCNSGGGL 63
           SGGS    SR GSG   GGG     G    GSG+R     +  G S   GGS    GGG 
Sbjct: 481 SGGSYGRGSRGGSGGSYGGGGS--GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGS 538

Query: 64  GSGACAGFLGNEHSLLSGN 82
           G G   G  G       GN
Sbjct: 539 GGGHSGGSGGGHSGGSGGN 557



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 6/66 (9%)

Query: 5   LSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLG 64
           L GG     S +G+G++  GG G   G+   G G+R     +  G  SGG +   GGG G
Sbjct: 458 LEGGQEDFES-SGAGKIGLGGRGGSGGS--YGRGSRGGSGGSYGGGGSGGGY---GGGSG 511

Query: 65  SGACAG 70
           S   +G
Sbjct: 512 SRGGSG 517



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)

Query: 18  SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
           SG   GG +G   GN   GSG+         G   GGS    G G   G  +GF G    
Sbjct: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSG----GGYGGGSGSRGGSGGSHGGGSGFGGESGG 598

Query: 78  LLSGNEKVT 86
              G E+ +
Sbjct: 599 SYGGGEEAS 607



 Score = 29.3 bits (64), Expect = 8.0
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 10/54 (18%)

Query: 14  SRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGA 67
           SR GSG   GGG+GF       G  +  S+    E   SGG +   GGG G  +
Sbjct: 578 SRGGSGGSHGGGSGF-------GGESGGSYGGGEEASGSGGGY---GGGSGKSS 621


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  298 bits (763), Expect = 7e-81
 Identities = 179/394 (45%), Positives = 233/394 (59%), Gaps = 14/394 (3%)

Query: 6   SGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGS 65
           +GG  R+ S    G          AG +       S     L G S   S C++ G +GS
Sbjct: 22  AGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPG-SYLSSECHTSGFVGS 80

Query: 66  GA--CAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCE 123
           G   C G         +G+EK TMQ LNDRLA+YL+ V  LE  NA+LE +I+  YE   
Sbjct: 81  GGWFCEGSF-------NGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQI 133

Query: 124 PGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALH 183
           P        DY  YF  IED +++I      NA +VLQ DNA+L ADDFR KYE EL+L 
Sbjct: 134 PYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLR 189

Query: 184 HSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVE 243
             VEAD +GLRR+LDELTLC  DLE Q E+L EEL  LKK+HEEE+ VL+   G  +NVE
Sbjct: 190 QLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVE 249

Query: 244 MNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNEL 303
           ++A P VDL  +L +MR +YE L E NR+D EAWFN ++  L QQ+          + E+
Sbjct: 250 VDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEI 309

Query: 304 TELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTET 363
            EL+R +  LEIELQ+  ++++S E +LAETE  Y +QL Q+Q  I  +E QL +IR + 
Sbjct: 310 IELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDL 369

Query: 364 EGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
           E Q  EY+ LLDVK  LE EI  Y +LL+GE+ K
Sbjct: 370 ERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCK 403


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  290 bits (743), Expect = 1e-78
 Identities = 170/372 (45%), Positives = 238/372 (63%), Gaps = 14/372 (3%)

Query: 78  LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
           L  GNEK+ MQNLNDRLASYL+ V  LE++N+ LE +IK  YE   P + R    DYS Y
Sbjct: 65  LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGR----DYSAY 120

Query: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
           +  IE+L+ QI  A + NA  VLQ DNA+L A+DFRLKYE E  +  +VEAD  GL +V 
Sbjct: 121 YRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVF 180

Query: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
           D+LTL  TDLEIQ E L+++L  LKK H+EE++ L    G  VNVE++A PG++L V++N
Sbjct: 181 DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMN 240

Query: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
            MR +YE +A++N ++A+  F  ++A LQQQ++ +         +LTEL+R  Q+LEIEL
Sbjct: 241 EMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIEL 300

Query: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
           QS +++K S E +L ET+  Y +QL  +Q  +  +E QL QIR+  E Q  EY  LLD+K
Sbjct: 301 QSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIK 360

Query: 378 IFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIG 437
             LE+EI  Y  LL+GE+   K+T Y+        S  + +D  +   +KTVV+E+   G
Sbjct: 361 TRLEQEIATYRRLLEGED--VKTTEYQL-------STLEERDIKKTRKIKTVVQEVVD-G 410

Query: 438 NLLSLRVHSVEE 449
            ++S  V  VEE
Sbjct: 411 KVVSSEVKEVEE 422


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  286 bits (733), Expect = 2e-77
 Identities = 171/397 (43%), Positives = 236/397 (59%), Gaps = 16/397 (4%)

Query: 6   SGGSRRICSRTGSGR-----LSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSG 60
           SGGS R+ +   S       LS     F A +V +G  +  + SC        G F  S 
Sbjct: 22  SGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSY 81

Query: 61  GGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYE 120
            G G     G+ G    +L+GNEK TMQ+LNDRLA YL+ V  LE+ NA LE +I+   E
Sbjct: 82  SGGG-----GWFGE--GILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCE 134

Query: 121 KCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENEL 180
           +  P        DY  YF  IE+L+++   +   NA +V++ DNA+L ADDFR KYE E+
Sbjct: 135 QQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEV 190

Query: 181 ALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNV 240
           +L   VE+D +GLRR+LD+LTLC +DLE Q E+L EEL  LKK+HEEE+  L+   G  +
Sbjct: 191 SLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRL 250

Query: 241 NVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAAR 300
           NVE++A P VDL  +L  MR +YE L E NR+DAE W + +S  L QQ+        + +
Sbjct: 251 NVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQ 310

Query: 301 NELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIR 360
            E+ EL+R +  LEIELQ+  +++ + E +LAETE  Y +QL Q+Q  I  +E QL +IR
Sbjct: 311 AEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIR 370

Query: 361 TETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
            + E Q  EY+ LLDV+  LE EI+ Y  LL+ E+ K
Sbjct: 371 ADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSK 407


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  271 bits (692), Expect = 1e-72
 Identities = 152/343 (44%), Positives = 213/343 (62%), Gaps = 5/343 (1%)

Query: 55  SFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQK 114
           S C +  G+      G   +E +  +GNEK TMQ LNDRLASYL  V  LE+ NA+LE +
Sbjct: 69  SSCQAASGISGSMGPGSWYSEGAF-NGNEKETMQFLNDRLASYLTRVRQLEQENAELESR 127

Query: 115 IKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRL 174
           I    ++           DY  +F  IE+L+++I      NA +V+  DNA+L ADDFR 
Sbjct: 128 I----QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRA 183

Query: 175 KYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQY 234
           KYE ELA+   VEAD +GLRR+LD+LTLC  DLE Q E+L EEL  LKK+HEEE+  L+ 
Sbjct: 184 KYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRC 243

Query: 235 TAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEG 294
             G  +N+E++A P VDLT +L  MR +YE + E NR+D E WFN +   L QQ++    
Sbjct: 244 QLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSE 303

Query: 295 AATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEE 354
                ++++ +L+R + TLEIELQ+  +++ S E +L E+E  Y +QL Q+Q  I  +E 
Sbjct: 304 QLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEA 363

Query: 355 QLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
           QL +IR + E Q  EY+ LLDV+  LE EI+ Y +LL+ E+ K
Sbjct: 364 QLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCK 406


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  269 bits (687), Expect = 5e-72
 Identities = 172/420 (40%), Positives = 237/420 (56%), Gaps = 29/420 (6%)

Query: 14  SRTGSGRLSGGGTGFV-------AGNVCVGSG-ARSSFSCTLEGISSGGSFCNSGGGLGS 65
           S+T S    G G G+        A  V  G+G AR S S T             GG  GS
Sbjct: 8   SQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPP------PGGSWGS 61

Query: 66  GACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPG 125
           G  +  LG       GN K TMQNLNDRLASYL+ V ALEEAN  LE +I   +++ +PG
Sbjct: 62  GRSSPLLG-------GNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPG 114

Query: 126 SSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHS 185
           S +    DYS+Y   I  L+ QI    + NA I+L  DNAR+  DDF LKYENE +    
Sbjct: 115 SKK----DYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKD 170

Query: 186 VEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMN 245
           +E +  GLRR LD LT+ TTDLE + E + +EL  +KK HE+EME     +  NVNV+++
Sbjct: 171 LEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVD 230

Query: 246 ATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTE 305
             P  DL  +L +MR EYE + ++  +D + W+ E+SA + Q+ +       + + ++ E
Sbjct: 231 TGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAAS-PATVQSRQGDIHE 289

Query: 306 LKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEG 365
           LKR  Q LEI+LQ+  + K + E  L+ET+  Y  +LQ +Q+ I   EE+L Q+R E E 
Sbjct: 290 LKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELER 349

Query: 366 QKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETI 425
           Q  EY+ LL +K  LEKEI  Y  LL+GE   S+ T  +SK    V++  + K  T+ETI
Sbjct: 350 QNNEYQVLLGIKTHLEKEITTYRRLLEGE---SEGTREESKSSMKVSATPKIKAITQETI 406


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  267 bits (683), Expect = 1e-71
 Identities = 159/374 (42%), Positives = 224/374 (59%), Gaps = 22/374 (5%)

Query: 41  SSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDH 100
           S   CTL G       CN    + +  C  F        +G+EK TMQ LNDRLASYL+ 
Sbjct: 25  SCHGCTLPGA------CNIPANVSN--CNWFCEGS---FNGSEKETMQFLNDRLASYLEK 73

Query: 101 VHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVL 160
           V  LE  NA+LE  I+ R ++ EP         Y  YF  IE+L+++I  +   NA +V+
Sbjct: 74  VRQLERDNAELENLIRERSQQQEPLVCAS----YQSYFKTIEELQQKILCSKSENARLVV 129

Query: 161 QNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTY 220
           Q DNA+L +DDFR KYE EL+L   VE+D +GLRR+LDELTLC +DLE Q E+L EEL  
Sbjct: 130 QIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLC 189

Query: 221 LKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNE 280
           LK++HE+E+  L+   G  +NVE++A P VDL  +LN  R++YE L E NR++ E WF  
Sbjct: 190 LKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFAT 249

Query: 281 RSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCN 340
           ++  L +Q+        + + E+ EL+R +  LEIELQ+   ++ S E +L E+E  Y +
Sbjct: 250 QTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSS 309

Query: 341 QLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK--- 397
           QL Q+Q  I  +E QL +IR++ E Q  EY+ LLDV+  LE EI+ Y +LL+ E+ K   
Sbjct: 310 QLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPS 369

Query: 398 ----SKSTCYKSKG 407
               + + C KS G
Sbjct: 370 NPCATTNACDKSTG 383


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  267 bits (682), Expect = 2e-71
 Identities = 155/355 (43%), Positives = 216/355 (60%), Gaps = 15/355 (4%)

Query: 41  SSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDH 100
           S  SCTL G       CN    + +  C  F        +G+EK TMQ LNDRLASYL+ 
Sbjct: 25  SCHSCTLPGA------CNIPANVSN--CNWFCEGS---FNGSEKETMQFLNDRLASYLEK 73

Query: 101 VHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVL 160
           V  LE  NA+LE  I+ R ++ EP         Y  YF  IE+L+++I      NA +V+
Sbjct: 74  VRQLERDNAELENLIRERSQQQEPLLCPS----YQSYFKTIEELQQKILCTKSENARLVV 129

Query: 161 QNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTY 220
           Q DNA+L ADDFR KY+ EL+L   VE+D +GLRR+LDELTLC +DLE Q E+L EEL  
Sbjct: 130 QIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLC 189

Query: 221 LKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNE 280
           LK +HE+E+  L+   G  +NVE++A P VDL  +LN  R++YE L E NR++ E WF  
Sbjct: 190 LKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTT 249

Query: 281 RSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCN 340
           ++  L +Q+        + + E+ EL+R +  LEIELQ+   ++ S E +L E+E  Y +
Sbjct: 250 QTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSS 309

Query: 341 QLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEE 395
           QL Q+Q  I  +E QL +IR++ E Q  EY+ LLDV+  LE EI+ Y +LL+ E+
Sbjct: 310 QLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESED 364


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  263 bits (671), Expect = 3e-70
 Identities = 158/382 (41%), Positives = 222/382 (58%), Gaps = 16/382 (4%)

Query: 37  SGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLAS 96
           S +R    C L    +G   CNS   +G+ A       E  + + NEK TMQ LNDRLAS
Sbjct: 50  SRSRGLTGCLLPCYFTGS--CNSPCLVGNCAWC-----EDGVFTSNEKETMQFLNDRLAS 102

Query: 97  YLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNA 156
           YL+ V +LEE NA+LE +I+   E+CE         DY RYF+ IEDL+++I      N+
Sbjct: 103 YLEKVRSLEETNAELESRIQ---EQCEQDIPMVCP-DYQRYFNTIEDLQQKILCTKAENS 158

Query: 157 SIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSE 216
            + +Q DN +L  DDF+ KYE+EL+L   +EAD S L  +L+ELTLC +DLE   E+L E
Sbjct: 159 RLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKE 218

Query: 217 ELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEA 276
           +L  LKK+HEEE+ +L+   G  ++VE++  P +DL  +L+ MR + E +   NR++AE 
Sbjct: 219 DLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEE 278

Query: 277 WFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEG 336
           W   ++  L QQ           + E+ ELKR    LEIELQ+  ++  S EC++AETE 
Sbjct: 279 WLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEA 338

Query: 337 NYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEER 396
            Y +QL QIQ  I  +E QL +IR + E Q  EY+ LLDVK  LE EI+ Y  LLD E+ 
Sbjct: 339 QYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDS 398

Query: 397 K-----SKSTCYKSKGYRPVNS 413
           +       +TC  S    P ++
Sbjct: 399 RLSCSPCSTTCTSSNTCEPCSA 420


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  263 bits (671), Expect = 3e-70
 Identities = 145/321 (45%), Positives = 206/321 (64%), Gaps = 4/321 (1%)

Query: 80  SGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFS 139
           +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+ R ++ EP         Y  YF 
Sbjct: 53  NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQSYFK 108

Query: 140 VIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDE 199
            IE+L+++I  +   NA +V+Q DNA+L ADDFR KY+ E +L   VE+D + LRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168

Query: 200 LTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNM 259
           LTLC +DLE Q E+L EEL  LK++HE+E+  L+   G  +NVE++A P VDL  +LN  
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228

Query: 260 RAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQS 319
           R +YE L E NR++ E WF  ++  L +Q+        + + E+ EL+R +  LEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 320 LMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIF 379
              +++S E +L E+E  Y +QL Q+Q  I  +E QL +IR++ E Q  EY+ LLDV+  
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 380 LEKEIDIYCNLLDGEERKSKS 400
           LE EI+ Y +LL+ E+ K  S
Sbjct: 349 LECEINTYRSLLESEDCKLPS 369


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  259 bits (661), Expect = 5e-69
 Identities = 157/364 (43%), Positives = 219/364 (60%), Gaps = 19/364 (5%)

Query: 36  GSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSG--NEKVTMQNLNDR 93
           GSG+R S S +       GS     GGL +G   G  G     + G  NEK TMQ+LNDR
Sbjct: 41  GSGSRISVSRSTSFRGGMGS-----GGLATGIAGGLAG-----MGGIQNEKETMQSLNDR 90

Query: 94  LASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATI 153
           LASYLD V +LE  N  LE KI+   EK  P        D+S YF +IEDL+ QI + T+
Sbjct: 91  LASYLDRVRSLETENRRLESKIREHLEKKGP-----QVRDWSHYFKIIEDLRAQIFANTV 145

Query: 154 CNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCET 213
            NA IVLQ DNARL ADDFR+KYE ELA+  SVE D  GLR+V+D+  +    LE + E 
Sbjct: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205

Query: 214 LSEELTYLKKSHEEEMEVLQ-YTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRK 272
           L EEL ++KK+HEEE++ LQ   A   + VE++A    DL  ++ ++RA+Y++LA +NR+
Sbjct: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265

Query: 273 DAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLA 332
           + + +++++       ++       AA   LTEL+R +Q+LEI+L S+  +K S E SL 
Sbjct: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325

Query: 333 ETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLL- 391
           E E  Y  Q++Q+   +  +E +L Q R E + Q  EYE LL++K+ LE EI  Y  LL 
Sbjct: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385

Query: 392 DGEE 395
           DGE+
Sbjct: 386 DGED 389


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  259 bits (661), Expect = 5e-69
 Identities = 157/364 (43%), Positives = 219/364 (60%), Gaps = 19/364 (5%)

Query: 36  GSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSG--NEKVTMQNLNDR 93
           GSG+R S S +       GS     GGL +G   G  G     + G  NEK TMQ+LNDR
Sbjct: 41  GSGSRISVSRSTSFRGGMGS-----GGLATGIAGGLAG-----MGGIQNEKETMQSLNDR 90

Query: 94  LASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATI 153
           LASYLD V +LE  N  LE KI+   EK  P        D+S YF +IEDL+ QI + T+
Sbjct: 91  LASYLDRVRSLETENRRLESKIREHLEKKGP-----QVRDWSHYFKIIEDLRAQIFANTV 145

Query: 154 CNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCET 213
            NA IVLQ DNARL ADDFR+KYE ELA+  SVE D  GLR+V+D+  +    LE + E 
Sbjct: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205

Query: 214 LSEELTYLKKSHEEEMEVLQ-YTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRK 272
           L EEL ++KK+HEEE++ LQ   A   + VE++A    DL  ++ ++RA+Y++LA +NR+
Sbjct: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265

Query: 273 DAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLA 332
           + + +++++       ++       AA   LTEL+R +Q+LEI+L S+  +K S E SL 
Sbjct: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325

Query: 333 ETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLL- 391
           E E  Y  Q++Q+   +  +E +L Q R E + Q  EYE LL++K+ LE EI  Y  LL 
Sbjct: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385

Query: 392 DGEE 395
           DGE+
Sbjct: 386 DGED 389


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  258 bits (658), Expect = 1e-68
 Identities = 143/318 (44%), Positives = 204/318 (64%), Gaps = 4/318 (1%)

Query: 80  SGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFS 139
           +G+EK TMQ LNDRLASYL+ V  LE  NA+LE+ I+ R ++ EP         Y  YF 
Sbjct: 95  NGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS----YQSYFK 150

Query: 140 VIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDE 199
            IE+L+++I  A   NA +V+  DNA+L +DDFR KY+ E +L   VE+D + +RR+LDE
Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210

Query: 200 LTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNM 259
           LTLC +DLE Q E+L EEL  LKK+HEEE+  L+   G  +NVE++  P VDL  +LN  
Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270

Query: 260 RAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQS 319
           R++YE L E NR++ E WF  ++  L +Q+        + + E+ EL+R +  LEIELQ+
Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330

Query: 320 LMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIF 379
              ++ S E +L E+E +Y +QL Q+Q  I  +E QL +IR + E Q  EY+ LLDV+  
Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390

Query: 380 LEKEIDIYCNLLDGEERK 397
           LE EI+ Y +LL+ E+ K
Sbjct: 391 LECEINTYRSLLESEDCK 408


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  248 bits (634), Expect = 6e-66
 Identities = 142/325 (43%), Positives = 193/325 (59%), Gaps = 6/325 (1%)

Query: 79  LSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYF 138
           ++ NEK TMQ LN+RLA+YL  V  LE  NA+LE KI+    K  P        DY  Y+
Sbjct: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147

Query: 139 SVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLD 198
           + IE+L+++I      N+ +V Q DN +LTADD R KYE E++L   VE+D +GL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 199 ELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNN 258
            LTL   DLE Q ++L EEL  LK +H+EE+  LQ   G  +++E+ A P  DL  +L  
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 259 MRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQ 318
           MR +YE + E NRKD E WFN +   L QQ+          + E+ EL+R++ TLE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 319 SLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKI 378
           +   ++ S EC L ETE  Y   L QIQ  I  +E QL +IR   E Q  EYE LLDVK 
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 379 FLEKEIDIYCNLLDGEERKSKSTCY 403
            LE EI  Y +LL+  +   K  CY
Sbjct: 388 RLECEITTYRSLLESSD--GKRPCY 410


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  242 bits (618), Expect = 5e-64
 Identities = 149/405 (36%), Positives = 223/405 (55%), Gaps = 24/405 (5%)

Query: 18  SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
           + R+  G T     ++C+   + ++  C L G       C+  G +G   C  +  N   
Sbjct: 52  ANRVRVGSTPLGRPSLCLPPTSHTA--CPLPGT------CHIPGNIG--ICGAYGKNT-- 99

Query: 78  LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
            L+G+EK TM+ LNDRLA+YL+ V  LE+ NA+LE  +  R  KC   +      DY  Y
Sbjct: 100 -LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLER-SKCHESTVCP---DYQSY 154

Query: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
           F  IE+L+++I  +   NA +++Q DNA+L ADDFR+K E+E +LH  VEAD  G +++L
Sbjct: 155 FRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLL 214

Query: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
           D+ TL   DLE Q E+L EE   LK +HE+E+++L+   G    +E++  P +DL  +L 
Sbjct: 215 DDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLG 274

Query: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
            MRA+YE + E N +D E WF  +S  +  Q           ++E+ EL+  +  LE+E 
Sbjct: 275 EMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVER 334

Query: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
           Q+   +K   + SL E E  Y  +L Q+Q  I  +EEQL +IR + E Q  EY+ LLDVK
Sbjct: 335 QAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVK 394

Query: 378 IFLEKEIDIYCNLLDGEERK-------SKSTCYKSKGYRPVNSGN 415
             LE EI  Y NLL+ E+ K       + ++C       PV  G+
Sbjct: 395 ARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGS 439


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  239 bits (609), Expect = 5e-63
 Identities = 144/380 (37%), Positives = 214/380 (56%), Gaps = 17/380 (4%)

Query: 18  SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
           + R+  G T     ++C+     ++  C L G       C+  G +G     G      +
Sbjct: 52  ANRVRVGSTPLGRPSLCLPPTCHTA--CPLPGT------CHIPGNIGICGAYG-----EN 98

Query: 78  LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
            L+G+EK TMQ LNDRLA+YL+ V  LE+ NA+LE  +  R  KC   +      DY  Y
Sbjct: 99  TLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLER-SKCHESTVCP---DYQSY 154

Query: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
           F  IE+L+++I  +   NA +++Q DNA+L ADDFR+K E+E +L   VEAD  G +++L
Sbjct: 155 FHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLL 214

Query: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
           D+ TL   DLE Q E+L EE   LK +HE+E+++L+   G  + +E++  P +DL  +L 
Sbjct: 215 DDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLG 274

Query: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
            MRA+YE + E NR+D E WF  +S  +  Q           ++E+ EL+  +  LE+E 
Sbjct: 275 EMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVER 334

Query: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
           Q+   +K   + SL E E  +  +L Q+Q  I  +EEQL +IR + E Q  EY+ LLDVK
Sbjct: 335 QAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVK 394

Query: 378 IFLEKEIDIYCNLLDGEERK 397
             LE EI  Y NLL+ E+ K
Sbjct: 395 TRLENEIATYRNLLESEDCK 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,652,413
Number of Sequences: 37866
Number of extensions: 759366
Number of successful extensions: 4971
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 374
Number of HSP's that attempted gapping in prelim test: 3362
Number of HSP's gapped (non-prelim): 1434
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.