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Search of human proteins with 30179903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 941 0.0
gi|4557853 transcription factor SOX9 [Homo sapiens] 385 e-107
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 361 e-100
gi|11967991 SRY-box 17 [Homo sapiens] 136 3e-32
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 129 4e-30
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 128 9e-30
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 124 2e-28
gi|5902106 SRY-box 15 [Homo sapiens] 122 5e-28
gi|5902108 SRY-box 21 [Homo sapiens] 122 5e-28
gi|8924248 SRY-box 18 [Homo sapiens] 122 9e-28
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 120 2e-27
gi|4759162 SRY-box 14 [Homo sapiens] 120 2e-27
gi|4507161 SRY-box 11 [Homo sapiens] 119 4e-27
gi|13899269 SRY-box 7 [Homo sapiens] 117 2e-26
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 115 1e-25
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 99 6e-21
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 99 6e-21
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 99 6e-21
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 98 2e-20
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 98 2e-20
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 98 2e-20
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 98 2e-20
gi|41406089 SRY-box 13 [Homo sapiens] 96 5e-20
gi|4507225 sex determining region Y [Homo sapiens] 95 1e-19
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 84 2e-16
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 84 2e-16
gi|112421108 capicua homolog [Homo sapiens] 67 3e-11
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 60 5e-09
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 60 5e-09
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 59 9e-09
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 941 bits (2433), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAA 60
MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAA
Sbjct: 1 MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDPAEAA 60
Query: 61 DERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKL 120
DERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKL
Sbjct: 61 DERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKL 120
Query: 121 ADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK 180
ADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK
Sbjct: 121 ADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK 180
Query: 181 AGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGA 240
AGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGA
Sbjct: 181 AGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGA 240
Query: 241 KPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPG 300
KPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPG
Sbjct: 241 KPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPG 300
Query: 301 QAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGS 360
QAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGS
Sbjct: 301 QAYGGAYFHAGASPVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGS 360
Query: 361 CSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLL 420
CSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLL
Sbjct: 361 CSGQSSATPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPRRPYASPLL 420
Query: 421 NGLALPPAHSPTSHWDQPVYTTLTRP 446
NGLALPPAHSPTSHWDQPVYTTLTRP
Sbjct: 421 NGLALPPAHSPTSHWDQPVYTTLTRP 446
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 385 bits (990), Expect = e-107
Identities = 237/495 (47%), Positives = 288/495 (58%), Gaps = 73/495 (14%)
Query: 19 ASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDP---AEAADERFPACIRDAVSQV 75
A S + EDS PS +GS+ +G+P E+ +++FP CIR+AVSQV
Sbjct: 21 APSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQV 80
Query: 76 LKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT 135
LKGYDW+LVPMPVR G K KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT
Sbjct: 81 LKGYDWTLVPMPVRVNGSS--KNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT 138
Query: 136 LGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPH 195
LGKLWRLL+ESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS K G ++++ E H
Sbjct: 139 LGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATE-QTH 197
Query: 196 PGGGAVYKA--------EAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELKLE 247
A++KA +G+ + H G+H+GQ+ GPPTPPTTPKT++Q K +LK E
Sbjct: 198 ISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQP--GKADLKRE 255
Query: 248 GRRPVDSGRQ-NIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGG--PAPPEPGQ-AY 303
GR + GRQ IDF +VDI ELSS+V+ ++ FDV+EFDQYLP G P GQ Y
Sbjct: 256 GRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTY 315
Query: 304 GGAY-------FHAGASPVWAHKS---------------APSASASPTETGPPRP----- 336
G+Y A A VW K AP A P P +P
Sbjct: 316 TGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQ 375
Query: 337 --------------------HIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPF 376
HIKTEQ SP HY +Q + SP + S + + P
Sbjct: 376 QPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPI 435
Query: 377 AGSQGDYGDLQ-ASSYYGAYPGYAPGLYQYPCFHSP-RRPYASPLLNGL---ALPPAHSP 431
SQ DY D Q +SSYY G GLY + +P +RP +P+ + ++P HSP
Sbjct: 436 TRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSP 495
Query: 432 TSHWDQPVYTTLTRP 446
HW+QPVYT LTRP
Sbjct: 496 -QHWEQPVYTQLTRP 509
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 361 bits (926), Expect = e-100
Identities = 230/478 (48%), Positives = 274/478 (57%), Gaps = 71/478 (14%)
Query: 10 QPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGA-----RGDPAEAADERF 64
+P C G+A S+ P G GL RA G EA D++F
Sbjct: 19 EPRCLSPGSAPSLG---------PDGGGGGSGL-RASPGPGELGKVKKEQQDGEADDDKF 68
Query: 65 PACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQY 124
P CIR+AVSQVL GYDW+LVPMPVR G A K+KPHVKRPMNAFMVWAQAARRKLADQY
Sbjct: 69 PVCIREAVSQVLSGYDWTLVPMPVRVNG--ASKSKPHVKRPMNAFMVWAQAARRKLADQY 126
Query: 125 PHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHS 184
PHLHNAELSKTLGKLWRLL+ES+KRPF+EEAERLR+QHKKDHPDYKYQPRRRK+ KA
Sbjct: 127 PHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQG 186
Query: 185 DSD-SGAELGPHPGGGAVYKA--EAGLGDGHHHGD-----------HTGQTHGPPTPPTT 230
+++ G E GG A +A ++ D H G+ +GQ+HGPPTPPTT
Sbjct: 187 EAECPGGE--AEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTT 244
Query: 231 PKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLP 290
PKTELQ A P K +GR + G+ +IDF NVDI E+S EVM M+ FDV E DQYLP
Sbjct: 245 PKTELQSGKADP--KRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETFDVAELDQYLP 302
Query: 291 LGG-----PAPPEPGQAYGGAYFHAGASPVWAHKSAPSASASPTETGP---PRPHIKTE- 341
G + G G A A W K P A PT + P + +KTE
Sbjct: 303 PNGHPGHVSSYSAAGYGLGSALAVASGHSAWISK--PPGVALPTVSPPGVDAKAQVKTET 360
Query: 342 --QPSPGHYGDQPRGS---------PDYGSCSGQSSATPAAPAGPFAGSQGDYGDLQASS 390
P HY DQP S P YG SA P+ + Q DY D Q S
Sbjct: 361 AGPQGPPHYTDQPSTSQIAYTSLSLPHYG------SAFPS-----ISRPQFDYSDHQPSG 409
Query: 391 YYGAYPGYAPGLYQYPCFHSP-RRPYASPLLN-GLALPPAHSPTSHWDQPVYTTLTRP 446
Y + G A GLY + P +RP + + + + P +HSPT HW+QPVYTTL+RP
Sbjct: 410 PYYGHSGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPT-HWEQPVYTTLSRP 466
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 136 bits (343), Expect = 3e-32
Identities = 98/252 (38%), Positives = 124/252 (49%), Gaps = 30/252 (11%)
Query: 91 GGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRP 150
G G K + ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L+ +EKRP
Sbjct: 57 GAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRP 116
Query: 151 FVEEAERLRVQHKKDHPDYKYQPRRRKSAKA----------GHSDSDSGAELGPHPGGGA 200
FVEEAERLRVQH +DHP+YKY+PRRRK K G ++ + A LGP GG
Sbjct: 117 FVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAA-LGPE--GGR 173
Query: 201 VYKAEAGLGDGHHHGDHTGQTHGPPTPPT---TPKTELQQAGAKPELKLEGRRPVDSGRQ 257
V A GLG G GPP P + Q GA P L+G
Sbjct: 174 V--AMDGLG---LQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPP---LDGYPLPTPDTS 225
Query: 258 NIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWA 317
+D + D + ++ + G A + + Q GP P G H P A
Sbjct: 226 PLDGVDPDPAFFAAPMPGDCPAAGTYSYAQVSDYAGPPEPPAGP------MHPRLGPEPA 279
Query: 318 HKSAPSASASPT 329
S P A P+
Sbjct: 280 GPSIPGLLAPPS 291
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 129 bits (325), Expect = 4e-30
Identities = 107/331 (32%), Positives = 147/331 (44%), Gaps = 61/331 (18%)
Query: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
H+KRPMNAFMVW+Q RRK+ +Q P +HNAE+SK LGK W+LL +S+K PF+ EAERLR+
Sbjct: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
Query: 161 QHKKDHPDYKYQPRRRKSAKAGHSDSDSGAEL----------------GPHPGGGAVYKA 204
+H D+PDYKY+P RK K+G+++S S A G H GGG +
Sbjct: 118 KHMADYPDYKYRP--RKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSS 175
Query: 205 EAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNV 264
AG G G G G + P + +++ K + + G +
Sbjct: 176 NAGGGGG---GASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAA 232
Query: 265 DISELSSEVMGTMDAFDVHEFDQYLPLGGPAPPEPGQAYGGAYFHAGASPVWAHKSAPSA 324
+ ++E G LPLG A + Y A AS SA SA
Sbjct: 233 AAASFAAEQAGAA---------ALLPLGAAA--DHHSLYKARTPSASASA----SSAASA 277
Query: 325 SASPTETGPPRPHIKTEQ----------PSP--------------GHYGDQPRG-SPDYG 359
SA+ G K ++ SP G Y ++ G SPD
Sbjct: 278 SAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAP 337
Query: 360 SCSGQSSATPAAPAGPFAGSQGDYGDLQASS 390
S SG+SSA + AG Y L+A+S
Sbjct: 338 SLSGRSSAASSPAAGRSPADHRGYASLRAAS 368
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 128 bits (322), Expect = 9e-30
Identities = 62/124 (50%), Positives = 81/124 (65%), Gaps = 2/124 (1%)
Query: 90 GGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKR 149
GGGGGA + VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+++SE+EKR
Sbjct: 39 GGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKR 98
Query: 150 PFVEEAERLRVQHKKDHPDYKYQPRRRKSA--KAGHSDSDSGAELGPHPGGGAVYKAEAG 207
PF++EA+RLR H K+HPDYKY+PRR+ K G GGGA G
Sbjct: 99 PFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVG 158
Query: 208 LGDG 211
+G G
Sbjct: 159 VGVG 162
Score = 29.6 bits (65), Expect = 5.8
Identities = 27/102 (26%), Positives = 33/102 (32%), Gaps = 28/102 (27%)
Query: 299 PGQAYGGAYFHA-----GASPVWAHKSAPSAS---------------------ASPTETG 332
PG A GG Y H GA P +A +A+ A P
Sbjct: 173 PGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPH 232
Query: 333 PPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAG 374
P PH P P H D G+ Y S A+P+G
Sbjct: 233 PHHPHAHPHNPQPMHRYDM--GALQYSPISNSQGYMSASPSG 272
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 124 bits (310), Expect = 2e-28
Identities = 65/120 (54%), Positives = 81/120 (67%), Gaps = 9/120 (7%)
Query: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
H+KRPMNAFMVW+Q RRK+ DQ+P +HNAE+SK LG+ W+LL +SEK PFV EAERLR+
Sbjct: 39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98
Query: 161 QHKKDHPDYKYQPRRRKS---AKA-----GHSDSDSGAELGPH-PGGGAVYKAEAGLGDG 211
+H D+PDYKY+PR++ AKA G S S + GP PG G A LG G
Sbjct: 99 KHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPLGGG 158
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 122 bits (307), Expect = 5e-28
Identities = 81/204 (39%), Positives = 103/204 (50%), Gaps = 37/204 (18%)
Query: 102 VKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQ 161
VKRPMNAFMVW+ A RR++A Q P +HN+E+SK LG W+LL E EKRPFVEEA+RLR +
Sbjct: 49 VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108
Query: 162 HKKDHPDYKYQPRRR-KSAKAGHSDSDSG----AELGPHPGGG-AVYKAEAGLGDGHHHG 215
H +D+PDYKY+PRR+ KS+ AG S G A GP G G A + G G
Sbjct: 109 HLRDYPDYKYRPRRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFG------ 162
Query: 216 DHTGQTHGPPTPPTTPKTELQQAGAKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMG 275
PP+ L + KLE P + + L E++
Sbjct: 163 ---------YRPPSYSTAYLPGSYGSSHCKLEAPSPCSLPQSD--------PRLQGELLP 205
Query: 276 TMDAFDVHEFDQYLPLGGPAPPEP 299
T + YLP G P P P
Sbjct: 206 T--------YTHYLPPGSPTPYNP 221
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 122 bits (307), Expect = 5e-28
Identities = 62/124 (50%), Positives = 78/124 (62%), Gaps = 19/124 (15%)
Query: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
K HVKRPMNAFMVW++A RRK+A + P +HN+E+SK LG W+LL+ESEKRPF++EA+
Sbjct: 3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAK 62
Query: 157 RLRVQHKKDHPDYKYQPRRRKS-------------------AKAGHSDSDSGAELGPHPG 197
RLR H K+HPDYKY+PRR+ A A H +GA L G
Sbjct: 63 RLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAG 122
Query: 198 GGAV 201
GG V
Sbjct: 123 GGLV 126
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 122 bits (305), Expect = 9e-28
Identities = 71/153 (46%), Positives = 90/153 (58%), Gaps = 4/153 (2%)
Query: 31 DAPPSP---AGSEGLGRAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMP 87
D PP+ A + G G A G A G PA A PA + + +
Sbjct: 12 DDPPARRDCAWAPGHGAAADTRGLAAG-PAALAAPAAPASPPSPQRSPPRSPEPGRYGLS 70
Query: 88 VRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESE 147
G G + ++RPMNAFMVWA+ R++LA Q P LHNA LSK LGK W+ L+ +E
Sbjct: 71 PAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAE 130
Query: 148 KRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAK 180
KRPFVEEAERLRVQH +DHP+YKY+PRR+K A+
Sbjct: 131 KRPFVEEAERLRVQHLRDHPNYKYRPRRKKQAR 163
Score = 28.9 bits (63), Expect = 9.9
Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 303 YGGAYFHAGASPVWAHKSAPSASASPT--ETGPPRPHIKTEQPSPGHYGDQPRG 354
+G A G + A +AP+A ASP + PPR P PG YG P G
Sbjct: 26 HGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPR------SPEPGRYGLSPAG 73
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 120 bits (302), Expect = 2e-27
Identities = 65/138 (47%), Positives = 84/138 (60%), Gaps = 14/138 (10%)
Query: 85 PMPVRGGGGGALKAKP----------HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSK 134
P GGGGG A VKRPMNAFMVW++ RRK+A + P +HN+E+SK
Sbjct: 14 PQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISK 73
Query: 135 TLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSAKAGHSDSDSGAELG 193
LG W+LLSE+EKRPF++EA+RLR H K+HPDYKY+PRR+ K+ + G L
Sbjct: 74 RLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLA 133
Query: 194 PHPGGGAVYKAEAGLGDG 211
P GG + G+G G
Sbjct: 134 P---GGNSMASGVGVGAG 148
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 120 bits (302), Expect = 2e-27
Identities = 50/80 (62%), Positives = 67/80 (83%)
Query: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
K H+KRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LLSE+EKRP+++EA+
Sbjct: 3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAK 62
Query: 157 RLRVQHKKDHPDYKYQPRRR 176
RLR QH K+HPDYKY+PRR+
Sbjct: 63 RLRAQHMKEHPDYKYRPRRK 82
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 119 bits (299), Expect = 4e-27
Identities = 64/149 (42%), Positives = 84/149 (56%), Gaps = 27/149 (18%)
Query: 98 AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157
A H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAER
Sbjct: 45 ASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAER 104
Query: 158 LRVQHKKDHPDYKYQPRRR----------------KSAKAGHSDSDSGAELGPHPGGGAV 201
LR++H D+PDYKY+PR++ KSA G S G G G+
Sbjct: 105 LRLKHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSS 164
Query: 202 YK-----------AEAGLGDGHHHGDHTG 219
K A+AG G GD+ G
Sbjct: 165 KKCGKLKAPAAAGAKAGAGKAAQSGDYGG 193
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 117 bits (293), Expect = 2e-26
Identities = 52/83 (62%), Positives = 70/83 (84%)
Query: 98 AKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAER 157
++ ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L+ S+KRP+V+EAER
Sbjct: 41 SESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAER 100
Query: 158 LRVQHKKDHPDYKYQPRRRKSAK 180
LR+QH +D+P+YKY+PRR+K AK
Sbjct: 101 LRLQHMQDYPNYKYRPRRKKQAK 123
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 115 bits (287), Expect = 1e-25
Identities = 58/117 (49%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Query: 90 GGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKR 149
GGGGG + VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL+++EKR
Sbjct: 129 GGGGGT--DQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKR 186
Query: 150 PFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEA 206
PF++EA+RLR H K++PDYKY+PRR+ + L P PG A A A
Sbjct: 187 PFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLP-PGAAAAAAAAA 242
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 99.4 bits (246), Expect = 6e-21
Identities = 40/80 (50%), Positives = 59/80 (73%)
Query: 99 KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERL 158
+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL
Sbjct: 167 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARL 226
Query: 159 RVQHKKDHPDYKYQPRRRKS 178
QH + +PDYKY+PR +++
Sbjct: 227 SKQHLEKYPDYKYKPRPKRT 246
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 99.4 bits (246), Expect = 6e-21
Identities = 40/80 (50%), Positives = 59/80 (73%)
Query: 99 KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERL 158
+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL
Sbjct: 540 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARL 599
Query: 159 RVQHKKDHPDYKYQPRRRKS 178
QH + +PDYKY+PR +++
Sbjct: 600 SKQHLEKYPDYKYKPRPKRT 619
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 99.4 bits (246), Expect = 6e-21
Identities = 40/80 (50%), Positives = 59/80 (73%)
Query: 99 KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERL 158
+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL
Sbjct: 553 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARL 612
Query: 159 RVQHKKDHPDYKYQPRRRKS 178
QH + +PDYKY+PR +++
Sbjct: 613 SKQHLEKYPDYKYKPRPKRT 632
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 97.8 bits (242), Expect = 2e-20
Identities = 40/85 (47%), Positives = 60/85 (70%)
Query: 94 GALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVE 153
G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ +S EK+P+ E
Sbjct: 626 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 685
Query: 154 EAERLRVQHKKDHPDYKYQPRRRKS 178
E RL H + +P+YKY+PR +++
Sbjct: 686 EQARLSKIHLEKYPNYKYKPRPKRT 710
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 97.8 bits (242), Expect = 2e-20
Identities = 40/85 (47%), Positives = 60/85 (70%)
Query: 94 GALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVE 153
G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ +S EK+P+ E
Sbjct: 586 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 645
Query: 154 EAERLRVQHKKDHPDYKYQPRRRKS 178
E RL H + +P+YKY+PR +++
Sbjct: 646 EQARLSKIHLEKYPNYKYKPRPKRT 670
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 97.8 bits (242), Expect = 2e-20
Identities = 40/85 (47%), Positives = 60/85 (70%)
Query: 94 GALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVE 153
G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ +S EK+P+ E
Sbjct: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
Query: 154 EAERLRVQHKKDHPDYKYQPRRRKS 178
E RL H + +P+YKY+PR +++
Sbjct: 649 EQARLSKIHLEKYPNYKYKPRPKRT 673
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 97.8 bits (242), Expect = 2e-20
Identities = 40/85 (47%), Positives = 60/85 (70%)
Query: 94 GALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVE 153
G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ +S EK+P+ E
Sbjct: 593 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 652
Query: 154 EAERLRVQHKKDHPDYKYQPRRRKS 178
E RL H + +P+YKY+PR +++
Sbjct: 653 EQARLSKIHLEKYPNYKYKPRPKRT 677
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 96.3 bits (238), Expect = 5e-20
Identities = 39/78 (50%), Positives = 57/78 (73%)
Query: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
H+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL
Sbjct: 423 HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSR 482
Query: 161 QHKKDHPDYKYQPRRRKS 178
QH + +PDYKY+PR +++
Sbjct: 483 QHLEKYPDYKYKPRPKRT 500
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 95.1 bits (235), Expect = 1e-19
Identities = 39/75 (52%), Positives = 61/75 (81%)
Query: 102 VKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQ 161
VKRPMNAF+VW++ RRK+A + P + N+E+SK LG W++L+E+EK PF +EA++L+
Sbjct: 60 VKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAM 119
Query: 162 HKKDHPDYKYQPRRR 176
H++ +P+YKY+PRR+
Sbjct: 120 HREKYPNYKYRPRRK 134
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 84.3 bits (207), Expect = 2e-16
Identities = 38/77 (49%), Positives = 54/77 (70%)
Query: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
HVKRPMNAFMVWA+ R LA P +NAE+S LG W LSE +K+P+ +EA++++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 161 QHKKDHPDYKYQPRRRK 177
+H+++ P + YQPR K
Sbjct: 396 KHREEFPGWVYQPRPGK 412
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 84.3 bits (207), Expect = 2e-16
Identities = 38/77 (49%), Positives = 54/77 (70%)
Query: 101 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRV 160
HVKRPMNAFMVWA+ R LA P +NAE+S LG W LSE +K+P+ +EA++++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 161 QHKKDHPDYKYQPRRRK 177
+H+++ P + YQPR K
Sbjct: 396 KHREEFPGWVYQPRPGK 412
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 67.4 bits (163), Expect = 3e-11
Identities = 83/350 (23%), Positives = 128/350 (36%), Gaps = 72/350 (20%)
Query: 27 DSDSDAPPSPAG--SEGLGRAGVAVGGARGDPAEAA---------DERFPACIRDAVSQV 75
+S PP P G G G A G P E D+ F + + +
Sbjct: 104 ESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLP 163
Query: 76 L---KGYDWSLVPMPV-------RGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYP 125
L K SL +P + G + K H++RPMNAFM++++ R + ++P
Sbjct: 164 LPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHP 223
Query: 126 HLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSD 185
+ N +SK LG+ W L EK+ + + A +++ H K HPD+K+ + RK
Sbjct: 224 NQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKK------- 276
Query: 186 SDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELK 245
S +E P GL GH + +EL A+ L
Sbjct: 277 --SSSEAKP---------TSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLS 325
Query: 246 LEGRRP------------------------VDSGRQNIDFSNVD---ISELSSEVMGTMD 278
+ + P SG ++D VD + EL+ V G
Sbjct: 326 SDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPAS 385
Query: 279 AFDVHEFDQYLPLGGPAP-PEPGQAYGGAYFHAGASPVWAHKSAPSASAS 327
QY G P P PG+ GGA G P+ +++ S A+
Sbjct: 386 YSGPKPSTQY---GAPGPFAAPGE--GGALAATGRPPLLPTRASRSQRAA 430
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 59.7 bits (143), Expect = 5e-09
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
K KPH+K+P+NAFM++ + R K+ + +A +++ LG+ W LS E+ + E A
Sbjct: 322 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 381
Query: 157 RLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEA 206
+ R H + +P + + K K D G G A YK +A
Sbjct: 382 KERQLHMQLYPGWSARDNYGKKKKR-KRDKQPGETNGEKKSAFATYKVKA 430
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 59.7 bits (143), Expect = 5e-09
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
K KPH+K+P+NAFM++ + R K+ + +A +++ LG+ W LS E+ + E A
Sbjct: 369 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 428
Query: 157 RLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEA 206
+ R H + +P + + K K D G G A YK +A
Sbjct: 429 KERQLHMQLYPGWSARDNYGKKKKR-KRDKQPGETNGEKKSAFATYKVKA 477
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 58.9 bits (141), Expect = 9e-09
Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 6/104 (5%)
Query: 97 KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156
K KPH+K+P+NAFM++ + R K+ + +A +++ LG+ W LS E+ + E A
Sbjct: 322 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 381
Query: 157 RLRVQHKKDHP------DYKYQPRRRKSAKAGHSDSDSGAELGP 194
+ R H + +P +Y + +R++ + G ++ S L P
Sbjct: 382 KERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNP 425
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,735,127
Number of Sequences: 37866
Number of extensions: 1473048
Number of successful extensions: 8175
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 476
Number of HSP's that attempted gapping in prelim test: 7029
Number of HSP's gapped (non-prelim): 1613
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.