Guide to the Human Genome
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Search of human proteins with 30089980

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30089980 chordin [Homo sapiens]
         (955 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30089980 chordin [Homo sapiens]                                   2006   0.0  
gi|40353769 chordin-like 2 [Homo sapiens]                             107   4e-23
gi|108773804 Fraser syndrome 1 [Homo sapiens]                         107   7e-23
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]    97   5e-20
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]    96   1e-19
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]    86   2e-16
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]                85   4e-16
gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]         78   3e-14
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]         74   5e-13
gi|37693519 BMP-binding endothelial regulator precursor protein ...    74   5e-13
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]          74   6e-13
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]         74   6e-13
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]             56   1e-07
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]             56   1e-07
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                  56   1e-07
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]               55   3e-07
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]               55   3e-07
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]     55   3e-07
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]               55   3e-07
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]       55   3e-07
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]     54   5e-07
gi|109150416 peroxidasin [Homo sapiens]                                51   5e-06
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa...    51   5e-06
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]         49   2e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      47   9e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    47   1e-04
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   47   1e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      46   1e-04
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       45   2e-04
gi|122937446 von Willebrand factor C domain-containing protein 2...    45   3e-04

>gi|30089980 chordin [Homo sapiens]
          Length = 955

 Score = 2006 bits (5197), Expect = 0.0
 Identities = 955/955 (100%), Positives = 955/955 (100%)

Query: 1   MPSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVRGAAGCTFGGKVYAL 60
           MPSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVRGAAGCTFGGKVYAL
Sbjct: 1   MPSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVRGAAGCTFGGKVYAL 60

Query: 61  DETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGH 120
           DETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGH
Sbjct: 61  DETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGH 120

Query: 121 CCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDGHTDFVALLTGPR 180
           CCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDGHTDFVALLTGPR
Sbjct: 121 CCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDGHTDFVALLTGPR 180

Query: 181 SQAVARARVSLLRSSLRFSISYRRLDRPTRIRFSDSNGSVLFEHPAAPTQDGLVCGVWRA 240
           SQAVARARVSLLRSSLRFSISYRRLDRPTRIRFSDSNGSVLFEHPAAPTQDGLVCGVWRA
Sbjct: 181 SQAVARARVSLLRSSLRFSISYRRLDRPTRIRFSDSNGSVLFEHPAAPTQDGLVCGVWRA 240

Query: 241 VPRLSLRLLRAEQLHVALVTLTHPSGEVWGPLIRHRALAAETFSAILTLEGPPQQGVGGI 300
           VPRLSLRLLRAEQLHVALVTLTHPSGEVWGPLIRHRALAAETFSAILTLEGPPQQGVGGI
Sbjct: 241 VPRLSLRLLRAEQLHVALVTLTHPSGEVWGPLIRHRALAAETFSAILTLEGPPQQGVGGI 300

Query: 301 TLLTLSDTEDSLHFLLLFRGLLEPRSGGLTQVPLRLQILHQGQLLRELQANVSAQEPGFA 360
           TLLTLSDTEDSLHFLLLFRGLLEPRSGGLTQVPLRLQILHQGQLLRELQANVSAQEPGFA
Sbjct: 301 TLLTLSDTEDSLHFLLLFRGLLEPRSGGLTQVPLRLQILHQGQLLRELQANVSAQEPGFA 360

Query: 361 EVLPNLTVQEMDWLVLGELQMALEWAGRPGLRISGHIAARKSCDVLQSVLCGADALIPVQ 420
           EVLPNLTVQEMDWLVLGELQMALEWAGRPGLRISGHIAARKSCDVLQSVLCGADALIPVQ
Sbjct: 361 EVLPNLTVQEMDWLVLGELQMALEWAGRPGLRISGHIAARKSCDVLQSVLCGADALIPVQ 420

Query: 421 TGAAGSASLTLLGNGSLIYQVQVVGTSSEVVAMTLETKPQRRDQRTVLCHMAGLQPGGHT 480
           TGAAGSASLTLLGNGSLIYQVQVVGTSSEVVAMTLETKPQRRDQRTVLCHMAGLQPGGHT
Sbjct: 421 TGAAGSASLTLLGNGSLIYQVQVVGTSSEVVAMTLETKPQRRDQRTVLCHMAGLQPGGHT 480

Query: 481 AVGICPGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVAALPYCGHSARHDTLPVPLAG 540
           AVGICPGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVAALPYCGHSARHDTLPVPLAG
Sbjct: 481 AVGICPGLGARGAHMLLQNELFLNVGTKDFPDGELRGHVAALPYCGHSARHDTLPVPLAG 540

Query: 541 ALVLPPVKSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGTPGPRRLLK 600
           ALVLPPVKSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGTPGPRRLLK
Sbjct: 541 ALVLPPVKSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGTPGPRRLLK 600

Query: 601 GFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHIANQCEVGGLRLEA 660
           GFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHIANQCEVGGLRLEA
Sbjct: 601 GFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHIANQCEVGGLRLEA 660

Query: 661 AGAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAP 720
           AGAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAP
Sbjct: 661 AGAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAP 720

Query: 721 NYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDP 780
           NYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDP
Sbjct: 721 NYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDP 780

Query: 781 GEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVR 840
           GEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVR
Sbjct: 781 GEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVR 840

Query: 841 VNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITC 900
           VNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITC
Sbjct: 841 VNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITC 900

Query: 901 RCGAGVPHCERDDCSLPLSCGSGKESRCCSRCTAHRRPAPETRTDPELEKEAEGS 955
           RCGAGVPHCERDDCSLPLSCGSGKESRCCSRCTAHRRPAPETRTDPELEKEAEGS
Sbjct: 901 RCGAGVPHCERDDCSLPLSCGSGKESRCCSRCTAHRRPAPETRTDPELEKEAEGS 955


>gi|40353769 chordin-like 2 [Homo sapiens]
          Length = 451

 Score =  107 bits (268), Expect = 4e-23
 Identities = 80/314 (25%), Positives = 109/314 (34%), Gaps = 83/314 (26%)

Query: 698 RPRDPNTCFFEGQQRPHGARWAPNYDP----LCSLCTCQRRT-VICDPVVCPPPSCPHPV 752
           R R    C F G++   G  W P  +P     C  CTC     V C  + CPP  CP PV
Sbjct: 26  RARPDMFCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPV 85

Query: 753 QAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCA 812
             P QCCP C E      L      R P + C  +G           H + P     +C 
Sbjct: 86  TEPQQCCPKCVEPHTPSGL------RAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCV 139

Query: 813 VCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC---------------PVGSGAH 857
           +C+C    G+++C    CP   C  P+ + P  CC+ C                +    H
Sbjct: 140 LCSCT--EGQIYCGLTTCPEPGCPAPLPL-PDSCCQACKDEASEQSDEEDSVQSLHGVRH 196

Query: 858 PQLGDPMQAD-----GP--------------------------------------RGCRF 874
           PQ  DP  +D     GP                                      + C  
Sbjct: 197 PQ--DPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVH 254

Query: 875 AGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGKE--SRCCSRC 932
            G+ +   + WHP+   FG + CI C C  G   C+R  C     C   ++   +CC  C
Sbjct: 255 GGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCKIC 314

Query: 933 TAHRRPAPETRTDP 946
                  PE + DP
Sbjct: 315 -------PEDKADP 321



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 61/227 (26%), Positives = 79/227 (34%), Gaps = 74/227 (32%)

Query: 690 PAKPGGPGRPRDPNTCFFEGQQRPHGARWA-----PNYDP-LCSLCTCQRRTVICDPVVC 743
           P  P G   P  P +C   G    HG  ++     P+  P  C LC+C    + C    C
Sbjct: 98  PHTPSGLRAP--PKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCTEGQIYCGLTTC 155

Query: 744 PPPSCPHPVQAPDQCCPVC--------PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAA 795
           P P CP P+  PD CC  C         E+  V+ L G+   +DP   C  D  R  R  
Sbjct: 156 PEPGCPAPLPLPDSCCQACKDEASEQSDEEDSVQSLHGVRHPQDP---CSSDAGRK-RGP 211

Query: 796 GTR--------------------------------------------------WHPVVPP 805
           GT                                                   WHP    
Sbjct: 212 GTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKACVHGGKTYSHGEVWHPAFRA 271

Query: 806 FGLIKCAVCTCKGGTGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
           FG + C +CTC+ G  +  C++V CP    C  P +V    CCK CP
Sbjct: 272 FGPLPCILCTCEDGRQD--CQRVTCPTEYPCRHPEKV-AGKCCKICP 315



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 39/130 (30%), Positives = 58/130 (44%), Gaps = 22/130 (16%)

Query: 2   PSLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVRGAAGCTFGGKVYALD 61
           P  PAP      L  +    RP +GAG     + ++ + +         C  GGK Y+  
Sbjct: 211 PGTPAPTGLSAPLSFIPRHFRP-KGAGSTTVKIVLKEKHKK-------ACVHGGKTYSHG 262

Query: 62  ETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP-ACGQPRQLPGH 120
           E WHP     FG + C+LC CE           GR  C+ +   CPT   C  P ++ G 
Sbjct: 263 EVWHPAF-RAFGPLPCILCTCE----------DGRQDCQRVT--CPTEYPCRHPEKVAGK 309

Query: 121 CCQTCPQERS 130
           CC+ CP++++
Sbjct: 310 CCKICPEDKA 319



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 33/89 (37%), Positives = 40/89 (44%), Gaps = 17/89 (19%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F GK Y+  E+WHP L EP G+M C+ C C              VSC  +   CP   
Sbjct: 33  CLFHGKRYSPGESWHPYL-EPQGLMYCLRCTCSE---------GAHVSCYRL--HCPPVH 80

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGL 139
           C QP   P  CC  C +  +     PSGL
Sbjct: 81  CPQPVTEPQQCCPKCVEPHT-----PSGL 104



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 39/124 (31%), Positives = 50/124 (40%), Gaps = 24/124 (19%)

Query: 665 GVRALGAPDTASAAPPVVPGLPA----LAPA-------KPGGPG--------RPRDPNTC 705
           GVR    P ++ A     PG PA     AP        +P G G        + +    C
Sbjct: 193 GVRHPQDPCSSDAGRKRGPGTPAPTGLSAPLSFIPRHFRPKGAGSTTVKIVLKEKHKKAC 252

Query: 706 FFEGQQRPHGARWAPNY---DPL-CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCCP 760
              G+   HG  W P +    PL C LCTC+     C  V CP    C HP +   +CC 
Sbjct: 253 VHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQDCQRVTCPTEYPCRHPEKVAGKCCK 312

Query: 761 VCPE 764
           +CPE
Sbjct: 313 ICPE 316



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 19/94 (20%)

Query: 76  RCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERS-SSER 134
           +CVLC+C            G++ C      CP P C  P  LP  CCQ C  E S  S+ 
Sbjct: 137 QCVLCSCTE----------GQIYCG--LTTCPEPGCPAPLPLPDSCCQACKDEASEQSDE 184

Query: 135 QPSGLSFEYPRDPEHRSYSDRGEPGAEERARGDG 168
           + S  S    R P+    SD G      R RG G
Sbjct: 185 EDSVQSLHGVRHPQDPCSSDAG------RKRGPG 212


>gi|108773804 Fraser syndrome 1 [Homo sapiens]
          Length = 4011

 Score =  107 bits (266), Expect = 7e-23
 Identities = 78/246 (31%), Positives = 93/246 (37%), Gaps = 66/246 (26%)

Query: 700 RDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQA---PD 756
           R P +C  E +   HG  WA +    CS+C+C    V C P  CPP SC H   A     
Sbjct: 90  RTPGSCHHEKKIHEHGTEWASSP---CSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEG 146

Query: 757 QCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTC 816
            CCPVC          G P S    EG  F     WR              L +CA C C
Sbjct: 147 SCCPVCVGL-------GKPCSY---EGHVFQDGEDWR--------------LSRCAKCLC 182

Query: 817 KGGTGEVHCEKVQCPRLACAQP---VRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCR 873
           + G  +  C   QC  L C Q    VRV P  CC QC                   R C 
Sbjct: 183 RNGVAQ--CFTAQCQPLFCNQDETVVRV-PGKCCPQC-----------------SARSCS 222

Query: 874 FAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG-----KESRC 928
            AGQ +   + W        E +C TC C  G   C +  C LPL CG G     +  +C
Sbjct: 223 AAGQVYEHGEQW-------SENACTTCICDRGEVRCHKQAC-LPLRCGKGQSRARRHGQC 274

Query: 929 CSRCTA 934
           C  C +
Sbjct: 275 CEECVS 280



 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 68/241 (28%), Positives = 86/241 (35%), Gaps = 61/241 (25%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQ-----APDQCC 759
           C ++         W P+    C  C C    VIC P VC  P C          A +QCC
Sbjct: 28  CVYQDSLLADATIWKPDS---CQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCC 84

Query: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
           P C               R PG  C+   ++     GT W           C+VC+C   
Sbjct: 85  PECV-------------LRTPG-SCHH--EKKIHEHGTEW-------ASSPCSVCSC--N 119

Query: 820 TGEVHCEKVQCPRLACA-QPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQW 878
            GEV C    CP L+C  Q +   P   C  CPV  G    LG P        C + G  
Sbjct: 120 HGEVRCTPQPCPPLSCGHQELAFIPEGSC--CPVCVG----LGKP--------CSYEGHV 165

Query: 879 FPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK-----ESRCCSRCT 933
           F + + W  S        C  C C  GV  C    C  PL C   +       +CC +C+
Sbjct: 166 FQDGEDWRLS-------RCAKCLCRNGVAQCFTAQCQ-PLFCNQDETVVRVPGKCCPQCS 217

Query: 934 A 934
           A
Sbjct: 218 A 218



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 57/246 (23%), Positives = 85/246 (34%), Gaps = 62/246 (25%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSC---PHPVQAPDQCCP 760
           +C   GQ   HG +W+ N    C+ C C R  V C    C P  C       +   QCC 
Sbjct: 220 SCSAAGQVYEHGEQWSEN---ACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCE 276

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDG-----DRSWRAAGTRWHPVVPPFGLIKCAVCT 815
            C                 P   C +DG     D  W+ +               C  C 
Sbjct: 277 ECVS---------------PAGSCSYDGVVRYQDEMWKGSA--------------CEFCM 307

Query: 816 CKGGTGEVHCEKVQCPRLACAQPVRVNPTD--CCKQCPVGSG--AHPQLGDPMQADGPRG 871
           C  G  +V C+  +C ++ CA+   +   D  CC +C   +G   + + G+ M ++    
Sbjct: 308 CDHG--QVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEV 365

Query: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS---GKESRC 928
            R      PE + W        +  C  C C      C    C  P   G+     + +C
Sbjct: 366 KR-----IPEGEKWE-------DGPCKVCECRGAQVTCYEPSCP-PCPVGTLALEVKGQC 412

Query: 929 CSRCTA 934
           C  CT+
Sbjct: 413 CPDCTS 418


>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
          Length = 1503

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 76/255 (29%), Positives = 99/255 (38%), Gaps = 68/255 (26%)

Query: 690 PAKPGGPGRPRDPNT--------CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPV 741
           P +P G   P  P+         C + G     G       DP CSLCTCQ  ++ C   
Sbjct: 755 PCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKK 814

Query: 742 VCPPPSCPHPVQAPDQC-CPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWH 800
            CPP  CPHP  +P  C CPVC           L + R+  +G  F+G            
Sbjct: 815 PCPPALCPHP--SPGPCFCPVCHS--------CLSQGREHQDGEEFEG------------ 852

Query: 801 PVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQL 860
               P G   C  C C+   G+V C ++QCP L C   V      CC +C          
Sbjct: 853 ----PAG--SCEWCRCQ--AGQVSCVRLQCPPLPCKLQV-TERGSCCPRC---------- 893

Query: 861 GDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSC 920
                    RGC   G+  PE   W   VPP  + +C +C C  GV  C R  C    SC
Sbjct: 894 ---------RGCLAHGEEHPEGSRW---VPP--DSACSSCVCHEGVVTCARIQCI--SSC 937

Query: 921 GSGKES--RCCSRCT 933
              ++    CC +C+
Sbjct: 938 AQPRQGPHDCCPQCS 952



 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 85/301 (28%), Positives = 106/301 (35%), Gaps = 83/301 (27%)

Query: 651 CEVGGLRLEAAGAEGVR--ALGAPDTASAAPPVVPGL--------PALAPAKPGGPGRPR 700
           CE+ G       AEGV+    G P TA      VP          P   P +P G   P 
Sbjct: 366 CELDGEEF----AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP- 420

Query: 701 DPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCP 760
             ++C +  Q   +G  +     P C  C CQ  TV C  V CPP +C  P   P QCCP
Sbjct: 421 SCDSCTYHSQVYANGQNFTDADSP-CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 479

Query: 761 VCP----EKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTC 816
            CP    E++   D       RDP                              C  C C
Sbjct: 480 RCPDCILEEEVFVDGESFSHPRDP------------------------------CQECRC 509

Query: 817 KGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAG 876
           +   G  HC+   CPR  CA P+   P  CC                   +   GC F G
Sbjct: 510 Q--EGHAHCQPRPCPRAPCAHPL---PGTCC------------------PNDCSGCAFGG 546

Query: 877 QWFPESQSW-HPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG--KESRCCSRCT 933
           + +P    + HPS P      C  CRC +G   C    C +PL C         CC +C 
Sbjct: 547 KEYPSGADFPHPSDP------CRLCRCLSGNVQCLARRC-VPLPCPEPVLLPGECCPQCP 599

Query: 934 A 934
           A
Sbjct: 600 A 600



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 77/258 (29%), Positives = 92/258 (35%), Gaps = 55/258 (21%)

Query: 675 ASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRR 734
           A   P   P  P   P    G   P D + C F G++ P GA +    DP C LC C   
Sbjct: 514 AHCQPRPCPRAPCAHPLP--GTCCPNDCSGCAFGGKEYPSGADFPHPSDP-CRLCRCLSG 570

Query: 735 TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRA 794
            V C    C P  CP PV  P +CCP CP         G PR   PG            A
Sbjct: 571 NVQCLARRCVPLPCPEPVLLPGECCPQCPAP------AGCPR---PG------------A 609

Query: 795 AGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGS 854
           A  R      P G   C  C C  G+  V C+++ CP   CA P R  P  CC  C    
Sbjct: 610 AHARHQEYFSPPG-DPCRRCLCLDGS--VSCQRLPCPPAPCAHP-RQGP--CCPSCD--- 660

Query: 855 GAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC 914
                           GC + G+ F   + +     P    +C  C C  G   CE   C
Sbjct: 661 ----------------GCLYQGKEFASGERF-----PSPTAACHLCLCWEGSVSCEPKAC 699

Query: 915 SLPLSCGSGKESRCCSRC 932
           + P  C       CC  C
Sbjct: 700 A-PALCPFPARGDCCPDC 716



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 59/229 (25%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           CF  G++   G       DP CS C C   +V C+P+ CPP  C HP + P QCCPVC  
Sbjct: 252 CFLNGREHRSGEPVGSG-DP-CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC-- 307

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
                            +GC + G +       R    +   GL  C  C+C+   GEV 
Sbjct: 308 -----------------DGCEYQGHQYQSQETFR----LQERGL--CVRCSCQ--AGEVS 342

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQS 884
           CE+ +CP   CA P         + CP                    C   G+ F E   
Sbjct: 343 CEEQECPVTPCALPASGR-----QLCP-------------------ACELDGEEFAEGVQ 378

Query: 885 WHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRC 932
           W P   P     C  C C  GVP C    C   P    +     CC  C
Sbjct: 379 WEPDGRP-----CTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 422



 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 74/264 (28%), Positives = 97/264 (36%), Gaps = 67/264 (25%)

Query: 686 PALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPP 745
           PAL P    G   P D + C + G+       +    +P C+LCTC    V C    C P
Sbjct: 701 PALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREP-CNLCTCLGGFVTCGRRPCEP 758

Query: 746 PSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPP 805
           P C HP+     CCP C                   +GC + G  +  A+G      + P
Sbjct: 759 PGCSHPLIPSGHCCPTC-------------------QGCRYHGVTT--ASGETLPDPLDP 797

Query: 806 FGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDC----CKQCPVGSGAHPQLG 861
                C++CTC+   G + C+K  CP   C  P   +P  C    C  C +  G   Q G
Sbjct: 798 ----TCSLCTCQ--EGSMRCQKKPCPPALCPHP---SPGPCFCPVCHSC-LSQGREHQDG 847

Query: 862 DPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSC 920
           +  + +GP G                        SC  CRC AG   C R  C  LP   
Sbjct: 848 E--EFEGPAG------------------------SCEWCRCQAGQVSCVRLQCPPLPCKL 881

Query: 921 GSGKESRCCSR---CTAHRRPAPE 941
              +   CC R   C AH    PE
Sbjct: 882 QVTERGSCCPRCRGCLAHGEEHPE 905



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 85/306 (27%), Positives = 104/306 (33%), Gaps = 81/306 (26%)

Query: 683  PGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVV 742
            P LP        G   PR    C   G++ P G+RW P  D  CS C C    V C  + 
Sbjct: 875  PPLPCKLQVTERGSCCPRCRG-CLAHGEEHPEGSRWVPP-DSACSSCVCHEGVVTCARIQ 932

Query: 743  CPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPV 802
            C   SC  P Q P  CCP C       D     R  +PGE                + P 
Sbjct: 933  CIS-SCAQPRQGPHDCCPQC------SDCEHEGRKYEPGES---------------FQPG 970

Query: 803  VPPFGLIKCAVCTCK---GGTGEVHCEKVQCPRLACAQPVRV---NPTDCCKQCP----- 851
              P     C VC C+    G   + C + QCP L    P ++    P  CC  C      
Sbjct: 971  ADP-----CEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSN 1025

Query: 852  -----VGS----------------------GAHPQLGDPM-QADGPRG-----CRFAGQW 878
                 +GS                       A P+L  P+ +   P G     CR   Q 
Sbjct: 1026 CSEGLLGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQS 1085

Query: 879  FPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK-----ESRCCSRCT 933
                     S   +   +C +C C AG   C+   CS PLSCG  K        CC RC 
Sbjct: 1086 CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCS-PLSCGPDKAPALSPGSCCPRCL 1144

Query: 934  AHRRPA 939
               RPA
Sbjct: 1145 P--RPA 1148



 Score = 83.6 bits (205), Expect = 8e-16
 Identities = 72/250 (28%), Positives = 94/250 (37%), Gaps = 56/250 (22%)

Query: 686 PALAPAKP-GGPGR--PRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVV 742
           P    A+P  GPG+  PR P+ C  E +    G  ++   DP C  C CQ     C P  
Sbjct: 463 PPTTCARPQSGPGQCCPRCPD-CILEEEVFVDGESFSHPRDP-CQECRCQEGHAHCQPRP 520

Query: 743 CPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPV 802
           CP   C HP+  P  CCP                  +   GC F G + + +     HP 
Sbjct: 521 CPRAPCAHPL--PGTCCP------------------NDCSGCAF-GGKEYPSGADFPHPS 559

Query: 803 VPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGD 862
            P      C +C C   +G V C   +C  L C +PV + P +CC QCP           
Sbjct: 560 DP------CRLCRCL--SGNVQCLARRCVPLPCPEPVLL-PGECCPQCP----------- 599

Query: 863 PMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS 922
                 P GC   G      Q +     P G+  C  C C  G   C+R  C  P  C  
Sbjct: 600 -----APAGCPRPGAAHARHQEY---FSPPGD-PCRRCLCLDGSVSCQRLPCP-PAPCAH 649

Query: 923 GKESRCCSRC 932
            ++  CC  C
Sbjct: 650 PRQGPCCPSC 659



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 60/267 (22%), Positives = 86/267 (32%), Gaps = 77/267 (28%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCP- 763
           C   GQ   +G  ++P+    C+ C C    V C    C   +C      P +CCP+C  
Sbjct: 138 CSQNGQTYGNGETFSPD---ACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCT 194

Query: 764 ------EKQDVRDLPGLP-------------RSRD------------PG------EGCYF 786
                 E       PG P             R R+            PG      +GC+ 
Sbjct: 195 EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFL 254

Query: 787 DGDRSWRAAGTRWHPVVPPFGL-IKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTD 845
           +G         R H    P G    C+ C C    G V CE + CP + C  P ++ P  
Sbjct: 255 NG---------REHRSGEPVGSGDPCSHCRC--ANGSVQCEPLPCPPVPCRHPGKI-PGQ 302

Query: 846 CCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAG 905
           CC  C                    GC + G  +   +++           C+ C C AG
Sbjct: 303 CCPVCD-------------------GCEYQGHQYQSQETFRLQERGL----CVRCSCQAG 339

Query: 906 VPHCERDDCSLPLSCGSGKESRCCSRC 932
              CE  +C +          + C  C
Sbjct: 340 EVSCEEQECPVTPCALPASGRQLCPAC 366



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 47/153 (30%), Positives = 62/153 (40%), Gaps = 32/153 (20%)

Query: 715  GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQ--APDQCCPVCPEKQDVRDLP 772
            G+  AP  DP C  C CQ  T +C    CP  SCP   +   P  CCPVC          
Sbjct: 1032 GSELAPP-DP-CYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVC---------- 1079

Query: 773  GLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPR 832
                 R P + C   G     A+G RW        +  C  C+C  GT  V C+  +C  
Sbjct: 1080 -----RAPTQSCVHQGREV--ASGERW-------TVDTCTSCSCMAGT--VRCQSQRCSP 1123

Query: 833  LACA--QPVRVNPTDCCKQCPVGSGAHPQLGDP 863
            L+C   +   ++P  CC +C     +    GDP
Sbjct: 1124 LSCGPDKAPALSPGSCCPRCLPRPASCMAFGDP 1156



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 18/113 (15%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           CT+  +VYA  + +  D   P     C  C C+           G V+C  +  +CP   
Sbjct: 425 CTYHSQVYANGQNF-TDADSP-----CHACHCQ----------DGTVTCSLV--DCPPTT 466

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEER 163
           C +P+  PG CC  CP      E    G SF +PRDP        G    + R
Sbjct: 467 CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPR 519



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 61/256 (23%), Positives = 74/256 (28%), Gaps = 84/256 (32%)

Query: 699 PRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQC 758
           P  P  C+  G+  P GARW P+    C+ C CQ     C P        PH        
Sbjct: 91  PASPQ-CWGLGRAWPEGARWEPD---ACTACVCQDGAAHCGPQA----HLPH-------- 134

Query: 759 CPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKG 818
           C  C +             +  G G  F  D                     C  C C  
Sbjct: 135 CRGCSQN-----------GQTYGNGETFSPDA--------------------CTTCRCL- 162

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQW 878
            TG V C+   C  L C +     P +CC  C    G+H + G                 
Sbjct: 163 -TGAVQCQGPSCSELNCLESC-TPPGECCPICCTEGGSHWEHG----------------- 203

Query: 879 FPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRCTA--- 934
               Q W     P     C  CRC  G   C + +C SL           CC  C     
Sbjct: 204 ----QEWTTPGDP-----CRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFL 254

Query: 935 ----HRRPAPETRTDP 946
               HR   P    DP
Sbjct: 255 NGREHRSGEPVGSGDP 270



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 23/111 (20%)

Query: 42  PLPVRGAA-----GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGR 96
           P P RG       GC + G+ Y  ++ + PD  EP     C LC C            G 
Sbjct: 705 PFPARGDCCPDCDGCEYLGESYLSNQEF-PDPREP-----CNLCTCLG----------GF 748

Query: 97  VSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
           V+C   +  C  P C  P    GHCC TC   R       SG +   P DP
Sbjct: 749 VTCG--RRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDP 797



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 41/151 (27%), Positives = 53/151 (35%), Gaps = 26/151 (17%)

Query: 798 RWHPVVPPFGLIKCAVCTCKGGTG------------EVHCEKVQCPRLACAQP--VRVNP 843
           +WHP+    G ++ AV   +                E H    QC  L  A P   R  P
Sbjct: 52  QWHPLREWLGRLEAAVMELREQNKDLQTRVRQLESCECHPASPQCWGLGRAWPEGARWEP 111

Query: 844 TDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCG 903
            D C  C    GA    G        RGC   GQ +   +++ P        +C TCRC 
Sbjct: 112 -DACTACVCQDGA-AHCGPQAHLPHCRGCSQNGQTYGNGETFSPD-------ACTTCRCL 162

Query: 904 AGVPHCERDDCSLPLSC--GSGKESRCCSRC 932
            G   C+   CS  L+C         CC  C
Sbjct: 163 TGAVQCQGPSCS-ELNCLESCTPPGECCPIC 192



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 26/130 (20%)

Query: 30  EPPVLPIRSEKEPLPVRG---AAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQ 86
           E PV P       LP  G      C   G+ +A    W PD G P     C  C C+   
Sbjct: 347 ECPVTPCA-----LPASGRQLCPACELDGEEFAEGVQWEPD-GRP-----CTACVCQ--- 392

Query: 87  WGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRD 146
                   G   C  +   CP   C  P Q PG CC +C      S+   +G +F     
Sbjct: 393 -------DGVPKCGAVL--CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADS 443

Query: 147 PEHRSYSDRG 156
           P H  +   G
Sbjct: 444 PCHACHCQDG 453



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 31/134 (23%)

Query: 30  EPPVLPIRSEKEPLP----VRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAP 85
           +P   P      PLP        +GC FGGK Y     + P   +P     C LC C + 
Sbjct: 517 QPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADF-PHPSDP-----CRLCRCLS- 569

Query: 86  QWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPR 145
                    G V C  +   C    C +P  LPG CC  CP         P+G       
Sbjct: 570 ---------GNVQC--LARRCVPLPCPEPVLLPGECCPQCP--------APAGCPRPGAA 610

Query: 146 DPEHRSY-SDRGEP 158
              H+ Y S  G+P
Sbjct: 611 HARHQEYFSPPGDP 624



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 30/116 (25%)

Query: 29  PEPPVLPIRSEKE-PLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQW 87
           PEP +LP     + P P    AGC   G  +A  + +    G+P     C  C C     
Sbjct: 585 PEPVLLPGECCPQCPAP----AGCPRPGAAHARHQEYFSPPGDP-----CRRCLCL---- 631

Query: 88  GRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCP------QERSSSERQPS 137
                  G VSC+ +   CP   C  PRQ  G CC +C       +E +S ER PS
Sbjct: 632 ------DGSVSCQRLP--CPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASGERFPS 677



 Score = 38.1 bits (87), Expect = 0.040
 Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 18/101 (17%)

Query: 51   CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
            C   G+ Y   E++ P      G   C +C CE PQ      GP  + C   + +CP+  
Sbjct: 954  CEHEGRKYEPGESFQP------GADPCEVCICE-PQ----PEGPPSLRCH--RRQCPSLV 1000

Query: 111  CGQPRQL----PGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
               P QL    P HCC TC +  S+      G     P DP
Sbjct: 1001 GCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELA-PPDP 1040



 Score = 37.4 bits (85), Expect = 0.067
 Identities = 28/98 (28%), Positives = 34/98 (34%), Gaps = 22/98 (22%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           GC+  G+ Y   ET+ PD         C  C C            G V C+   P C   
Sbjct: 137 GCSQNGQTYGNGETFSPDA--------CTTCRCLT----------GAVQCQG--PSCSEL 176

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
            C +    PG CC  C  E  S      G  +  P DP
Sbjct: 177 NCLESCTPPGECCPICCTEGGS--HWEHGQEWTTPGDP 212



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 19/98 (19%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           GC   G+ +     W P          C  C C            G V+C  I  +C + 
Sbjct: 895 GCLAHGEEHPEGSRWVPPDSA------CSSCVCHE----------GVVTCARI--QCIS- 935

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
           +C QPRQ P  CC  C        +   G SF+   DP
Sbjct: 936 SCAQPRQGPHDCCPQCSDCEHEGRKYEPGESFQPGADP 973



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 19/58 (32%), Positives = 23/58 (39%), Gaps = 13/58 (22%)

Query: 69  GEPFGVMR-CVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTC 125
           GEP G    C  C C            G V C+ +   CP   C  P ++PG CC  C
Sbjct: 262 GEPVGSGDPCSHCRC----------ANGSVQCEPLP--CPPVPCRHPGKIPGQCCPVC 307



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 22/77 (28%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPE--CPT 108
           CT GG  +   + W    G+P  + RC+                G + C+  +    CP 
Sbjct: 193 CTEGGSHWEHGQEWTTP-GDPCRICRCL---------------EGHIQCRQRECASLCPY 236

Query: 109 PACGQPRQLPGHCCQTC 125
           PA    R LPG CC  C
Sbjct: 237 PA----RPLPGTCCPVC 249



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 29/108 (26%), Positives = 39/108 (36%), Gaps = 32/108 (29%)

Query: 51   CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
            C   G+  A  E W  D         C  C+C A          G V C++    C   +
Sbjct: 1086 CVHQGREVASGERWTVDT--------CTSCSCMA----------GTVRCQS--QRCSPLS 1125

Query: 111  CG---QPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDR 155
            CG    P   PG CC  C        R  S ++F    DP +R++  R
Sbjct: 1126 CGPDKAPALSPGSCCPRC------LPRPASCMAF---GDPHYRTFDGR 1164



 Score = 31.2 bits (69), Expect = 4.8
 Identities = 34/136 (25%), Positives = 45/136 (33%), Gaps = 19/136 (13%)

Query: 3   SLPAPPAPLLLLGLLLLGSRPARGAGPEPPVLPIRSEKEPLPVRGAAGCTFGGKVYALDE 62
           +LP P  P   L     GS   +   P PP L       P        C   G+ +   E
Sbjct: 790 TLPDPLDPTCSLCTCQEGSMRCQKK-PCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGE 848

Query: 63  TWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCC 122
            +    G       C  C C+A          G+VSC  ++ +CP   C       G CC
Sbjct: 849 EFEGPAGS------CEWCRCQA----------GQVSC--VRLQCPPLPCKLQVTERGSCC 890

Query: 123 QTCPQERSSSERQPSG 138
             C    +  E  P G
Sbjct: 891 PRCRGCLAHGEEHPEG 906


>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
          Length = 814

 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 87/306 (28%), Positives = 108/306 (35%), Gaps = 83/306 (27%)

Query: 651 CEVGGLRLEAAGAEGVR--ALGAPDTASAAPPVVPGL--------PALAPAKPGGPGRPR 700
           CE+ G       AEGV+    G P TA      VP          P   P +P G   P 
Sbjct: 424 CELDGEEF----AEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCP- 478

Query: 701 DPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCP 760
             ++C +  Q   +G  +     P C  C CQ  TV C  V CPP +C  P   P QCCP
Sbjct: 479 SCDSCTYHSQVYANGQNFTDADSP-CHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCP 537

Query: 761 VCP----EKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTC 816
            CP    E++   D       RDP                              C  C C
Sbjct: 538 RCPDCILEEEVFVDGESFSHPRDP------------------------------CQECRC 567

Query: 817 KGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAG 876
           +   G  HC+   CPR  CA P+   P  CC                   +   GC F G
Sbjct: 568 Q--EGHAHCQPRPCPRAPCAHPL---PGTCC------------------PNDCSGCAFGG 604

Query: 877 QWFPESQSW-HPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG--KESRCCSRCT 933
           + +P    + HPS P      C  CRC +G   C    C +PL C         CC +C 
Sbjct: 605 KEYPSGADFPHPSDP------CRLCRCLSGNVQCLARRC-VPLPCPEPVLLPGECCPQCP 657

Query: 934 AHRRPA 939
           A   PA
Sbjct: 658 AAPAPA 663



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 77/258 (29%), Positives = 92/258 (35%), Gaps = 52/258 (20%)

Query: 675 ASAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRR 734
           A   P   P  P   P    G   P D + C F G++ P GA +    DP C LC C   
Sbjct: 572 AHCQPRPCPRAPCAHPLP--GTCCPNDCSGCAFGGKEYPSGADFPHPSDP-CRLCRCLSG 628

Query: 735 TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRA 794
            V C    C P  CP PV  P +CCP CP         G PR   PG            A
Sbjct: 629 NVQCLARRCVPLPCPEPVLLPGECCPQCPAAPAP---AGCPR---PG------------A 670

Query: 795 AGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGS 854
           A  R      P G   C  C C  G+  V C+++ CP   CA P R  P  CC  C    
Sbjct: 671 AHARHQEYFSPPG-DPCRRCLCLDGS--VSCQRLPCPPAPCAHP-RQGP--CCPSCD--- 721

Query: 855 GAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC 914
                           GC + G+ F   + +     P    +C  C C  G   CE   C
Sbjct: 722 ----------------GCLYQGKEFASGERF-----PSPTAACHLCLCWEGSVSCEPKAC 760

Query: 915 SLPLSCGSGKESRCCSRC 932
           + P  C       CC  C
Sbjct: 761 A-PALCPFPARGDCCPDC 777



 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 59/229 (25%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           CF  G++   G       DP CS C C   +V C+P+ CPP  C HP + P QCCPVC  
Sbjct: 310 CFLNGREHRSGEPVGSG-DP-CSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC-- 365

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
                            +GC + G +       R    +   GL  C  C+C+   GEV 
Sbjct: 366 -----------------DGCEYQGHQYQSQETFR----LQERGL--CVRCSCQ--AGEVS 400

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQS 884
           CE+ +CP   CA P         + CP                    C   G+ F E   
Sbjct: 401 CEEQECPVTPCALPASGR-----QLCP-------------------ACELDGEEFAEGVQ 436

Query: 885 WHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRC 932
           W P   P     C  C C  GVP C    C   P    +     CC  C
Sbjct: 437 WEPDGRP-----CTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSC 480



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 73/250 (29%), Positives = 95/250 (38%), Gaps = 53/250 (21%)

Query: 686 PALAPAKP-GGPGR--PRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVV 742
           P    A+P  GPG+  PR P+ C  E +    G  ++   DP C  C CQ     C P  
Sbjct: 521 PPTTCARPQSGPGQCCPRCPD-CILEEEVFVDGESFSHPRDP-CQECRCQEGHAHCQPRP 578

Query: 743 CPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPV 802
           CP   C HP+  P  CCP                  +   GC F G + + +     HP 
Sbjct: 579 CPRAPCAHPL--PGTCCP------------------NDCSGCAF-GGKEYPSGADFPHPS 617

Query: 803 VPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGD 862
            P      C +C C   +G V C   +C  L C +PV + P +CC QCP           
Sbjct: 618 DP------CRLCRCL--SGNVQCLARRCVPLPCPEPVLL-PGECCPQCPA---------- 658

Query: 863 PMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS 922
              A  P GC   G      Q +     P G+  C  C C  G   C+R  C  P  C  
Sbjct: 659 ---APAPAGCPRPGAAHARHQEY---FSPPGD-PCRRCLCLDGSVSCQRLPCP-PAPCAH 710

Query: 923 GKESRCCSRC 932
            ++  CC  C
Sbjct: 711 PRQGPCCPSC 720



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 70/282 (24%), Positives = 91/282 (32%), Gaps = 73/282 (25%)

Query: 690 PAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCP 749
           P    G   P     C +EGQ    G  +  + +P C  CTC R  V C  + CPP  CP
Sbjct: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP-CLQCTCLRSRVRCMALKCPPSPCP 235

Query: 750 HPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLI 809
            PV  P  CCP C                   +GC  +G   W   G  W     P    
Sbjct: 236 EPVLRPGHCCPTC-------------------QGC-TEGGSHWE-HGQEWTTPGDP---- 270

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC--------------PVGSG 855
            C +C C    G + C + +C  L C  P R  P  CC  C              PVGSG
Sbjct: 271 -CRICRCL--EGHIQCRQRECASL-CPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSG 326

Query: 856 --------------AHPQLGDPMQADGP-----------RGCRFAGQWFPESQSWHPSVP 890
                           P    P+    P            GC + G  +   +++     
Sbjct: 327 DPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQER 386

Query: 891 PFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGKESRCCSRC 932
                 C+ C C AG   CE  +C +          + C  C
Sbjct: 387 GL----CVRCSCQAGEVSCEEQECPVTPCALPASGRQLCPAC 424



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 62/250 (24%), Positives = 81/250 (32%), Gaps = 67/250 (26%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C   GQ   +G  ++P+    C+ C C   T+ C+   CP   CP     P  CCP C  
Sbjct: 138 CSQNGQTYGNGETFSPD---ACTTCRCLEGTITCNQKPCPRGPCPE----PGACCPHCK- 189

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
                             GC ++G + +    T      P      C  CTC      V 
Sbjct: 190 -----------------PGCDYEG-QLYEEGVTFLSSSNP------CLQCTCL--RSRVR 223

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQS 884
           C  ++CP   C +PV + P  CC  C                   +GC   G  +   Q 
Sbjct: 224 CMALKCPPSPCPEPV-LRPGHCCPTC-------------------QGCTEGGSHWEHGQE 263

Query: 885 WHPSVPPFGEMSCITCRCGAGVPHCERDDC-SLPLSCGSGKESRCCSRCTA-------HR 936
           W     P     C  CRC  G   C + +C SL           CC  C         HR
Sbjct: 264 WTTPGDP-----CRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDGCFLNGREHR 318

Query: 937 RPAPETRTDP 946
              P    DP
Sbjct: 319 SGEPVGSGDP 328



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 18/113 (15%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           CT+  +VYA  + +  D   P     C  C C+           G V+C  +  +CP   
Sbjct: 483 CTYHSQVYANGQNF-TDADSP-----CHACHCQ----------DGTVTCSLV--DCPPTT 524

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEER 163
           C +P+  PG CC  CP      E    G SF +PRDP        G    + R
Sbjct: 525 CARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPR 577



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 26/130 (20%)

Query: 30  EPPVLPIRSEKEPLPVRG---AAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQ 86
           E PV P       LP  G      C   G+ +A    W PD G P     C  C C+   
Sbjct: 405 ECPVTPCA-----LPASGRQLCPACELDGEEFAEGVQWEPD-GRP-----CTACVCQ--- 450

Query: 87  WGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRD 146
                   G   C  +   CP   C  P Q PG CC +C      S+   +G +F     
Sbjct: 451 -------DGVPKCGAVL--CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADS 501

Query: 147 PEHRSYSDRG 156
           P H  +   G
Sbjct: 502 PCHACHCQDG 511



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/115 (30%), Positives = 46/115 (40%), Gaps = 25/115 (21%)

Query: 29  PEPPVLPIRSEKEPLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWG 88
           PEP +LP     +       AGC   G  +A  + +    G+P     C  C C      
Sbjct: 643 PEPVLLPGECCPQCPAAPAPAGCPRPGAAHARHQEYFSPPGDP-----CRRCLCL----- 692

Query: 89  RRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCP------QERSSSERQPS 137
                 G VSC+ +   CP   C  PRQ  G CC +C       +E +S ER PS
Sbjct: 693 -----DGSVSCQRLP--CPPAPCAHPRQ--GPCCPSCDGCLYQGKEFASGERFPS 738



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 24/112 (21%)

Query: 42  PLPVRGAA------GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPG 95
           P P  GA       GC + G++Y    T+            C+ C C             
Sbjct: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP------CLQCTCLR----------S 220

Query: 96  RVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDP 147
           RV C  +K  CP   C +P   PGHCC TC            G  +  P DP
Sbjct: 221 RVRCMALK--CPPSPCPEPVLRPGHCCPTCQGCTEGGSHWEHGQEWTTPGDP 270



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 28/134 (20%)

Query: 30  EPPVLPIRSEKEPLP----VRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAP 85
           +P   P      PLP        +GC FGGK Y     + P   +P     C LC C + 
Sbjct: 575 QPRPCPRAPCAHPLPGTCCPNDCSGCAFGGKEYPSGADF-PHPSDP-----CRLCRCLS- 627

Query: 86  QWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPR 145
                    G V C  +   C    C +P  LPG CC  CP     +   P+G       
Sbjct: 628 ---------GNVQC--LARRCVPLPCPEPVLLPGECCPQCP-----AAPAPAGCPRPGAA 671

Query: 146 DPEHRSY-SDRGEP 158
              H+ Y S  G+P
Sbjct: 672 HARHQEYFSPPGDP 685



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 20/95 (21%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           GC+  G+ Y   ET+ PD         C  C C            G ++C N KP CP  
Sbjct: 137 GCSQNGQTYGNGETFSPD--------ACTTCRCL----------EGTITC-NQKP-CPRG 176

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP 144
            C +P     HC   C  E    E   + LS   P
Sbjct: 177 PCPEPGACCPHCKPGCDYEGQLYEEGVTFLSSSNP 211



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 22/78 (28%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPE--CP 107
           GCT GG  +   + W    G+P  + RC+                G + C+  +    CP
Sbjct: 250 GCTEGGSHWEHGQEWTTP-GDPCRICRCL---------------EGHIQCRQRECASLCP 293

Query: 108 TPACGQPRQLPGHCCQTC 125
            PA    R LPG CC  C
Sbjct: 294 YPA----RPLPGTCCPVC 307



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 19/58 (32%), Positives = 23/58 (39%), Gaps = 13/58 (22%)

Query: 69  GEPFGVMR-CVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQPRQLPGHCCQTC 125
           GEP G    C  C C            G V C+ +   CP   C  P ++PG CC  C
Sbjct: 320 GEPVGSGDPCSHCRC----------ANGSVQCEPLP--CPPVPCRHPGKIPGQCCPVC 365


>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
          Length = 955

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 82/301 (27%), Positives = 108/301 (35%), Gaps = 75/301 (24%)

Query: 679 PPVVPGLPALAPAKPGGPGRPR---DPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRT 735
           P ++ G     P+ P GP  PR    P+ C+  G      +RW    +P CS C C+   
Sbjct: 357 PSLLQGEVMGTPSSPRGPESPRLAAGPSPCWHLGAMHESRSRWT---EPGCSQCWCEDGK 413

Query: 736 VICDPVVCPPPSCPHPVQAPD-QCCPVC-----------------PEKQDVR-------- 769
           V C+ V C   +C HP+ + D  CCP C                 P  ++          
Sbjct: 414 VTCEKVRC-EAACSHPIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNENCTVCVCLAGN 472

Query: 770 ------DLPGLPRSRDPGEG--------CYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCT 815
                 + P  P    P           CYF G   W A G      V   G  +C  C 
Sbjct: 473 VSCISPECPSGPCQTPPQTDCCTCVPVRCYFHG--RWYADG-----AVFSGGGDECTTCV 525

Query: 816 CKGGTGEVHCEKVQCPRLAC-AQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRF 874
           C+   GEV C  + CP LAC  +  R+ P  CC  C   +   P  G  +  +G      
Sbjct: 526 CQ--NGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPT---PSTGCSLDDNGVE---- 576

Query: 875 AGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKESRCCSRCT 933
               FP  Q W P  P      C  C C A G   C+R DC            +CC  C+
Sbjct: 577 ----FPIGQIWSPGDP------CELCICQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCS 626

Query: 934 A 934
           A
Sbjct: 627 A 627



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 64/255 (25%), Positives = 94/255 (36%), Gaps = 56/255 (21%)

Query: 688 LAPAKPGGPGRPRD--------PNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICD 739
           ++P  P GP +           P  C+F G+    GA ++   D  C+ C CQ   V C 
Sbjct: 476 ISPECPSGPCQTPPQTDCCTCVPVRCYFHGRWYADGAVFSGGGDE-CTTCVCQNGEVECS 534

Query: 740 PVVCPPPSCPHPV--QAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGT 797
            + CP  +CP       P QCC  C E               P  GC  D +      G 
Sbjct: 535 FMPCPELACPREEWRLGPGQCCFTCQEP-------------TPSTGCSLDDNGVEFPIGQ 581

Query: 798 RWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAH 857
            W P  P      C +C C+   G V C++  C   +C  P+R+ P  CC  C       
Sbjct: 582 IWSPGDP------CELCICQ-ADGSVSCKRTDCVD-SCPHPIRI-PGQCCPDCSA----- 627

Query: 858 PQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLP 917
                        GC + G+ F  ++++   + P     C++C C  G   C   DC + 
Sbjct: 628 -------------GCTYTGRIFYNNETFPSVLDP-----CLSCICLLGSVACSPVDCPIT 669

Query: 918 LSCGSGKESRCCSRC 932
            +     +  CC  C
Sbjct: 670 CTYPFHPDGECCPVC 684



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 63/234 (26%), Positives = 80/234 (34%), Gaps = 57/234 (24%)

Query: 709 GQQRPHGARWAPNYDPLCSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQD 767
           G + P G  W+P  DP C LC CQ   +V C    C   SCPHP++ P QCCP C     
Sbjct: 574 GVEFPIGQIWSPG-DP-CELCICQADGSVSCKRTDCVD-SCPHPIRIPGQCCPDC----- 625

Query: 768 VRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEK 827
                          GC + G          ++    P  L  C  C C    G V C  
Sbjct: 626 -------------SAGCTYTG-------RIFYNNETFPSVLDPCLSCICL--LGSVACSP 663

Query: 828 VQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHP 887
           V CP + C  P   +  +CC  C                   R C + G+     Q    
Sbjct: 664 VDCP-ITCTYPFHPD-GECCPVC-------------------RDCNYEGRKVANGQ---- 698

Query: 888 SVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGKESRCCSRCTAHRRPAPE 941
            V    +  C  C C  G   CE+  C    +  +     CCS C     P  E
Sbjct: 699 -VFTLDDEPCTRCTCQLGEVSCEKVPCQRACADPALLPGDCCSSCPDSLSPLEE 751



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 24/88 (27%)

Query: 40  KEPLPVRGAAGCTF--GGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRV 97
           +EP P   + GC+    G  + + + W P  G+P     C LC C+A          G V
Sbjct: 560 QEPTP---STGCSLDDNGVEFPIGQIWSP--GDP-----CELCICQAD---------GSV 600

Query: 98  SCKNIKPECPTPACGQPRQLPGHCCQTC 125
           SCK  + +C   +C  P ++PG CC  C
Sbjct: 601 SCK--RTDC-VDSCPHPIRIPGQCCPDC 625



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 19/115 (16%)

Query: 48  AAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECP 107
           +AGCT+ G+++  +ET+ P + +P     C+ C C            G V+C  +  +CP
Sbjct: 626 SAGCTYTGRIFYNNETF-PSVLDP-----CLSCICLL----------GSVACSPV--DCP 667

Query: 108 TPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPGAEE 162
              C  P    G CC  C        +  +G  F    +P  R     GE   E+
Sbjct: 668 I-TCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEPCTRCTCQLGEVSCEK 721



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 32/106 (30%), Positives = 43/106 (40%), Gaps = 22/106 (20%)

Query: 35  PIRSEKEPLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGP 94
           P   + E  PV     C + G+  A  + +  D  EP     C  C C+           
Sbjct: 673 PFHPDGECCPV--CRDCNYEGRKVANGQVFTLD-DEP-----CTRCTCQL---------- 714

Query: 95  GRVSCKNIKPECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLS 140
           G VSC+ +  +    AC  P  LPG CC +CP   S  E +  GLS
Sbjct: 715 GEVSCEKVPCQ---RACADPALLPGDCCSSCPDSLSPLE-EKQGLS 756



 Score = 34.3 bits (77), Expect = 0.57
 Identities = 28/91 (30%), Positives = 33/91 (36%), Gaps = 26/91 (28%)

Query: 42  PLPVR------GAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPG 95
           P+P R         GC   G V A  + + P          C +C C A          G
Sbjct: 428 PIPSRDGGCCPSCTGCFHSGVVRAEGDVFSPPNEN------CTVCVCLA----------G 471

Query: 96  RVSCKNIKPECPTPACGQPRQLPGHCCQTCP 126
            VSC  I PECP+  C  P Q    CC   P
Sbjct: 472 NVSC--ISPECPSGPCQTPPQT--DCCTCVP 498



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 35/125 (28%), Positives = 47/125 (37%), Gaps = 33/125 (26%)

Query: 29  PEPPVLPIRSEKEP-----LPVRGAAGCTFGGKVYALDETWHPDLGEPF--GVMRCVLCA 81
           PE P  P ++  +      +PVR    C F G+       W+ D G  F  G   C  C 
Sbjct: 478 PECPSGPCQTPPQTDCCTCVPVR----CYFHGR-------WYAD-GAVFSGGGDECTTCV 525

Query: 82  CEAPQWGRRTRGPGRVSCKNIKPECPTPACGQP--RQLPGHCCQTCPQERSSSERQPSGL 139
           C+           G V C  +   CP  AC +   R  PG CC TC +   S+       
Sbjct: 526 CQN----------GEVECSFMP--CPELACPREEWRLGPGQCCFTCQEPTPSTGCSLDDN 573

Query: 140 SFEYP 144
             E+P
Sbjct: 574 GVEFP 578


>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
          Length = 1036

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 78/286 (27%), Positives = 106/286 (37%), Gaps = 45/286 (15%)

Query: 662 GAEGVRALGAPDTASAAPPVVPGLPALAPAKPGGPGRPR--DPNTCFFEGQQR-PHGARW 718
           G E    +  P  A   P + PG    + A      +P    P+ C   G +    G  W
Sbjct: 634 GREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETW 693

Query: 719 APNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSR 778
             N D  C+ CTC    V+C+  VCPP  C +P +  D CCP C + Q  R  P L R+ 
Sbjct: 694 --NIDS-CTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTD-QPFR--PSLSRNN 747

Query: 779 DPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQP 838
                C  D    + AA + W P V       C  C C      + C    CP ++C +P
Sbjct: 748 SVPNYCKNDEGDIFLAAES-WKPDV-------CTSCICIDSV--ISCFSESCPSVSCERP 797

Query: 839 VRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRG--CRFAGQWFPESQSWHPSVPPFGEMS 896
           V +    CC  C             ++   P+   C F+G+ + + + W          S
Sbjct: 798 V-LRKGQCCPYC-------------IEDTIPKKVVCHFSGKAYADEERWDLD-------S 836

Query: 897 CITCRCGAGVPHCERDDCSLPLSCGS--GKESRCCSRCTAHRRPAP 940
           C  C C  G   C    C  PL C      E  CC  C     P P
Sbjct: 837 CTHCYCLQGQTLCSTVSCP-PLPCVEPINVEGSCCPMCPEMYVPEP 881



 Score = 80.1 bits (196), Expect = 9e-15
 Identities = 72/265 (27%), Positives = 97/265 (36%), Gaps = 58/265 (21%)

Query: 674 TASAAPPVVPGLPALAPAKPGGPGRPRDPNTCF-FEGQQRPHGARWAPNYDPLCSLCTCQ 732
           +ASA PP++ G                   TC   +G    +   W       C  C C 
Sbjct: 596 SASAGPPILSG-------------------TCLTVDGHHHKNEESWHDG----CRECYCL 632

Query: 733 RRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVR--DLPGLPRSRDPGEGCYFDGDR 790
               +C  + CP P+C +P   P QCCP C +   V+  +L        PG G YF    
Sbjct: 633 NGREMCALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHAPG-GEYFVEGE 691

Query: 791 SWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
           +W               +  C  CTC   +G V CE   CP L C  P R   + CC QC
Sbjct: 692 TW--------------NIDSCTQCTCH--SGRVLCETEVCPPLLCQNPSRTQDS-CCPQC 734

Query: 851 PVGSGAHPQLGDPMQADGPRGCR-FAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHC 909
                  P L        P  C+   G  F  ++SW P V       C +C C   V  C
Sbjct: 735 -TDQPFRPSLS--RNNSVPNYCKNDEGDIFLAAESWKPDV-------CTSCICIDSVISC 784

Query: 910 ERDDCSLPLSCGSG--KESRCCSRC 932
             + C   +SC     ++ +CC  C
Sbjct: 785 FSESCP-SVSCERPVLRKGQCCPYC 808



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 62/230 (26%), Positives = 86/230 (37%), Gaps = 43/230 (18%)

Query: 726 CSLCTCQRRTVICDPVVCPPPSCPHPV----QAPDQC-CPVCPEKQDVRDLPGLPRSRDP 780
           C +C C+ R   C P++C    CP  +       D C C  CPE    +  P L   +D 
Sbjct: 527 CEICECRPRPKKCRPIIC-DKYCPLGLLKNKHGCDICRCKKCPELSCSKICP-LGFQQD- 583

Query: 781 GEGCYFDGDRSWRAAGTRWHPVVPPFGLI--------------KCAVCTCKGGTGEVHCE 826
             GC     R   A+ +   P++    L                C  C C    G   C 
Sbjct: 584 SHGCLICKCR--EASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYCL--NGREMCA 639

Query: 827 KVQCPRLACAQPVRVNPTDCCKQCPVGSGAH-PQLGDPMQADGPRGCRFAGQWFPESQSW 885
            + CP  AC  P  ++P  CC  C        P+L  P     P      G++F E ++W
Sbjct: 640 LITCPVPACGNPT-IHPGQCCPSCADDFVVQKPELSTPSICHAP-----GGEYFVEGETW 693

Query: 886 HPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSC--GSGKESRCCSRCT 933
           +         SC  C C +G   CE + C  PL C   S  +  CC +CT
Sbjct: 694 NID-------SCTQCTCHSGRVLCETEVCP-PLLCQNPSRTQDSCCPQCT 735



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 57/219 (26%), Positives = 74/219 (33%), Gaps = 42/219 (19%)

Query: 726 CSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCY 785
           C  C CQ    IC    C   +C        +CCPVC +       P  P +     GCY
Sbjct: 354 CRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCED-------PVYPFNNP--AGCY 404

Query: 786 FDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTD 845
            +G     A G RW           C  C C    GE HC    C +  C  PV+V P +
Sbjct: 405 ANG--LILAHGDRWRE-------DDCTFCQCV--NGERHCVATVCGQ-TCTNPVKV-PGE 451

Query: 846 CCKQCPVGSGAHPQL--GDPMQADGPRGCRFAGQWFPESQSWHPSVPPF--GEMSCITCR 901
           CC  C       P +   DP        C   G+           +  F      C TC+
Sbjct: 452 CCPVC-----EEPTIITVDPPACGELSNCTLTGK---------DCINGFKRDHNGCRTCQ 497

Query: 902 CGAGVPHC--ERDDCSLPLSCGSGKESRCCSRCTAHRRP 938
           C      C   +  C+L    G   +++ C  C    RP
Sbjct: 498 CINTEELCSERKQGCTLNCPFGFLTDAQNCEICECRPRP 536



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 66/280 (23%), Positives = 97/280 (34%), Gaps = 64/280 (22%)

Query: 701 DPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCP 760
           +P  C+  G    HG RW  +    C+ C C      C   VC   +C +PV+ P +CCP
Sbjct: 399 NPAGCYANGLILAHGDRWREDD---CTFCQCVNGERHCVATVCGQ-TCTNPVKVPGECCP 454

Query: 761 VCPEKQDVR-DLPG---LPRSRDPGEGCY------FDGDRSWRAAGT--------RWHPV 802
           VC E   +  D P    L      G+ C        +G R+ +   T        +   +
Sbjct: 455 VCEEPTIITVDPPACGELSNCTLTGKDCINGFKRDHNGCRTCQCINTEELCSERKQGCTL 514

Query: 803 VPPFGLI----KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDC----CKQCP-VG 853
             PFG +     C +C C+    +  C  + C +  C   +  N   C    CK+CP + 
Sbjct: 515 NCPFGFLTDAQNCEICECRPRPKK--CRPIICDKY-CPLGLLKNKHGCDICRCKKCPELS 571

Query: 854 SGAHPQLGDPMQADGPRGCR-------------------FAGQWFPESQSWHPSVPPFGE 894
                 LG    + G   C+                     G      +SWH        
Sbjct: 572 CSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKNEESWHD------- 624

Query: 895 MSCITCRCGAGVPHCERDDCSLPLSCGSG--KESRCCSRC 932
             C  C C  G   C    C +P +CG+      +CC  C
Sbjct: 625 -GCRECYCLNGREMCALITCPVP-ACGNPTIHPGQCCPSC 662



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/250 (23%), Positives = 75/250 (30%), Gaps = 78/250 (31%)

Query: 726 CSLCTCQR------RTVICDPV---VCPPPSCPHPVQ-APDQCCPVCPEKQDVRDLPGLP 775
           C L  C+       RTV C PV    CPP S    V+   D CC +    + +  L G P
Sbjct: 242 CDLYECKPVFGVDCRTVECPPVQQTACPPDSYETQVRLTADGCCTLPTRCECLSGLCGFP 301

Query: 776 RSR-------------DPGEGC-------------------YFDGDRSWRAAGTRWHPVV 803
                            PG+ C                   Y+DGD              
Sbjct: 302 VCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNVEYYDGDM------------- 348

Query: 804 PPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDP 863
             F +  C  C C+GG     C   QC  + C +   V   +CC  C           DP
Sbjct: 349 --FRMDNCRFCRCQGGVAI--CFTAQCGEINCER-YYVPEGECCPVCE----------DP 393

Query: 864 MQA-DGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGS 922
           +   + P GC   G        W        E  C  C+C  G  HC    C    +   
Sbjct: 394 VYPFNNPAGCYANGLILAHGDRWR-------EDDCTFCQCVNGERHCVATVCGQTCTNPV 446

Query: 923 GKESRCCSRC 932
                CC  C
Sbjct: 447 KVPGECCPVC 456



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 20/77 (25%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F GK YA +E W  D         C  C C            G+  C  +   CP   
Sbjct: 819 CHFSGKAYADEERWDLD--------SCTHCYCLQ----------GQTLCSTVS--CPPLP 858

Query: 111 CGQPRQLPGHCCQTCPQ 127
           C +P  + G CC  CP+
Sbjct: 859 CVEPINVEGSCCPMCPE 875



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 25/85 (29%), Positives = 31/85 (36%), Gaps = 21/85 (24%)

Query: 44  PVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIK 103
           P+      T  G  +  +E+WH           C  C C            GR  C  I 
Sbjct: 602 PILSGTCLTVDGHHHKNEESWHDG---------CRECYCLN----------GREMCALIT 642

Query: 104 PECPTPACGQPRQLPGHCCQTCPQE 128
             CP PACG P   PG CC +C  +
Sbjct: 643 --CPVPACGNPTIHPGQCCPSCADD 665



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 26/103 (25%), Positives = 33/103 (32%), Gaps = 30/103 (29%)

Query: 29  PEPPVLPIRSEKEPLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWG 88
           PE    P+  E    P    AGC   G + A  + W  D         C  C        
Sbjct: 382 PEGECCPV-CEDPVYPFNNPAGCYANGLILAHGDRWRED--------DCTFC-------- 424

Query: 89  RRTRGPGRVSCKNIKPECPTPACGQ----PRQLPGHCCQTCPQ 127
                     C N +  C    CGQ    P ++PG CC  C +
Sbjct: 425 ---------QCVNGERHCVATVCGQTCTNPVKVPGECCPVCEE 458



 Score = 33.5 bits (75), Expect = 0.97
 Identities = 20/75 (26%), Positives = 27/75 (36%), Gaps = 20/75 (26%)

Query: 54  GGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQ 113
           GG+ +   ETW+ D         C  C C +          GRV C+     CP   C  
Sbjct: 683 GGEYFVEGETWNID--------SCTQCTCHS----------GRVLCET--EVCPPLLCQN 722

Query: 114 PRQLPGHCCQTCPQE 128
           P +    CC  C  +
Sbjct: 723 PSRTQDSCCPQCTDQ 737



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 18/74 (24%), Positives = 28/74 (37%), Gaps = 20/74 (27%)

Query: 55  GKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQP 114
           G ++   E+W PD+        C  C C              +SC      CP+ +C +P
Sbjct: 758 GDIFLAAESWKPDV--------CTSCICI----------DSVISC--FSESCPSVSCERP 797

Query: 115 RQLPGHCCQTCPQE 128
               G CC  C ++
Sbjct: 798 VLRKGQCCPYCIED 811


>gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
          Length = 377

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 57/211 (27%), Positives = 75/211 (35%), Gaps = 67/211 (31%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
           C F+ ++   G RW P  +P     C  C C     V+C  V CP   C  PV  P  CC
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96

Query: 760 PVCPEKQDV-----------------------RDLPGLPRSRDPGEGCYFDGDRSWRAA- 795
           P CP   ++                       R     P SR  G    F G RS R A 
Sbjct: 97  PRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRGAL 156

Query: 796 ----------------------------------GTRWHPVVPPFGLIKCAVCTCKGGTG 821
                                             G  WHP +  FG+++C +CTC     
Sbjct: 157 MDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--NVT 214

Query: 822 EVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
           +  C+K+ CP R  C  P +++   CCK CP
Sbjct: 215 KQECKKIHCPNRYPCKYPQKID-GKCCKVCP 244



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 14/118 (11%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F  K Y + E WHP L EP+G++ CV C C            G V C  ++  CP   
Sbjct: 37  CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
           C  P  +P  CC  CP +   S     G  F  P  R+  H  +    +P    +A G
Sbjct: 85  CLSPVHIPHLCCPRCPGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 142



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 17/93 (18%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
           C   GK Y+  E+WHP+L   FG++ CVLC C             +  CK I   CP   
Sbjct: 181 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 227

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFE 142
            C  P+++ G CC+ CP +++   ++  G SF+
Sbjct: 228 PCKYPQKIDGKCCKVCPGKKA---KELPGQSFD 257



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 6/74 (8%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
           C   G+   HG  W PN        C LCTC      C  + CP    C +P +   +CC
Sbjct: 181 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 240

Query: 760 PVCPEKQDVRDLPG 773
            VCP K+  ++LPG
Sbjct: 241 KVCPGKK-AKELPG 253



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 4/64 (6%)

Query: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
           C F  + +   + WHP + P+G + C+ C C   G   C R  C   + C S       C
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95

Query: 929 CSRC 932
           C RC
Sbjct: 96  CPRC 99


>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
          Length = 458

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 13/151 (8%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
           C F+ ++   G RW P  +P     C  C C     V+C  V CP   C  PV  P  CC
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96

Query: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
           P CPE      LP +  ++   + C ++G             +       +C  C+C   
Sbjct: 97  PRCPED----SLPPV-NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC--S 149

Query: 820 TGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
            G V+C    CP+L CA PV V P  CC+ C
Sbjct: 150 EGNVYCGLKTCPKLTCAFPVSV-PDSCCRVC 179



 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 56/213 (26%), Positives = 75/213 (35%), Gaps = 68/213 (31%)

Query: 704 TCFFEGQQRPHGARWAP-----NYDP-LCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQ 757
           +C + G    HG  +       N  P  C+ C+C    V C    CP  +C  PV  PD 
Sbjct: 115 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 174

Query: 758 CCPVC------------------PEKQDVRDLPGL-----PRSRDPGEGCYFDGDRSWRA 794
           CC VC                  P  ++ R          P SR  G    F G RS R 
Sbjct: 175 CCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 234

Query: 795 A-----------------------------------GTRWHPVVPPFGLIKCAVCTCKGG 819
           A                                   G  WHP +  FG+++C +CTC   
Sbjct: 235 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--N 292

Query: 820 TGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
             +  C+K+ CP R  C  P +++   CCK CP
Sbjct: 293 VTKQECKKIHCPNRYPCKYPQKID-GKCCKVCP 324



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 14/84 (16%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
           C   GK Y+  E+WHP+L   FG++ CVLC C             +  CK I   CP   
Sbjct: 261 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 307

Query: 110 ACGQPRQLPGHCCQTCPQERSSSE 133
            C  P+++ G CC+ CP +++  E
Sbjct: 308 PCKYPQKIDGKCCKVCPGKKAKEE 331



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 28/78 (35%), Positives = 37/78 (47%), Gaps = 12/78 (15%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F  K Y + E WHP L EP+G++ CV C C            G V C  ++  CP   
Sbjct: 37  CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84

Query: 111 CGQPRQLPGHCCQTCPQE 128
           C  P  +P  CC  CP++
Sbjct: 85  CLSPVHIPHLCCPRCPED 102



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
           C   G+   HG  W PN        C LCTC      C  + CP    C +P +   +CC
Sbjct: 261 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 320

Query: 760 PVCPEKQDVRDLPG 773
            VCP K+   +LPG
Sbjct: 321 KVCPGKKAKEELPG 334



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)

Query: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
           C F  + +   + WHP + P+G + C+ C C   G   C R  C   + C S       C
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95

Query: 929 CSRCTAHRRP 938
           C RC     P
Sbjct: 96  CPRCPEDSLP 105



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 51  CTFGGKVYALDETWHPD-LGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           C + G  Y   E +  + L +     +C  C+C            G V C  +K  CP  
Sbjct: 116 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE----------GNVYC-GLKT-CPKL 163

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
            C  P  +P  CC+ C  +   S     G  F  P  R+  H  +    +P    +A G
Sbjct: 164 TCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 222


>gi|37693519 BMP-binding endothelial regulator precursor protein
           [Homo sapiens]
          Length = 685

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 62/236 (26%), Positives = 83/236 (35%), Gaps = 50/236 (21%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQ--APDQCCPVC 762
           C FEG Q   G  + P     C+ C+C      C   VCP  SCP  +    P QCCP C
Sbjct: 166 CVFEGVQYQEGEEFQPEGSK-CTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKC 224

Query: 763 PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGE 822
             ++ V DL        P   C F  D     +          F    C  CTC+  T  
Sbjct: 225 LGQRKVFDL--------PFGSCLFRSDVYDNGSS---------FLYDNCTACTCRDST-- 265

Query: 823 VHCEKVQCPRLACAQP--VRVNPTDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFP 880
                V C R  C+ P         CC++C +           +  +  + C+F  + F 
Sbjct: 266 -----VVCKR-KCSHPGGCDQGQEGCCEECLL----------RVPPEDIKVCKFGNKIFQ 309

Query: 881 ESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK---ESRCCSRCT 933
           + + W         ++C  C C  G   C    C    SC  GK      CC  CT
Sbjct: 310 DGEMW-------SSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICT 358



 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 64/230 (27%), Positives = 83/230 (36%), Gaps = 50/230 (21%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C +EG       +W    +P C L  CQ   V    V C    C +P++    CCP CP 
Sbjct: 108 CTYEGNTYNSSFKWQSPAEP-CVLRQCQEGVVTESGVRCVV-HCKNPLEHLGMCCPTCP- 164

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
                             GC F+G +     G  + P        KC  C+C G  G   
Sbjct: 165 ------------------GCVFEGVQ--YQEGEEFQPEGS-----KCTKCSCTG--GRTQ 197

Query: 825 CEKVQCPRLACAQPV-RVNPTDCCKQCPVGSGAHPQLGDPMQADGPRG-CRFAGQWFPES 882
           C +  CP L+C Q +  + P  CC +C         LG     D P G C F    +   
Sbjct: 198 CVREVCPILSCPQHLSHIPPGQCCPKC---------LGQRKVFDLPFGSCLFRSDVYDNG 248

Query: 883 QSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGKESRCCSRC 932
            S       F   +C  C C      C+R  CS P  C  G+E  CC  C
Sbjct: 249 SS-------FLYDNCTACTCRDSTVVCKR-KCSHPGGCDQGQEG-CCEEC 289



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 44/161 (27%), Positives = 62/161 (38%), Gaps = 28/161 (17%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCP 763
           +C F      +G+ +   YD  C+ CTC+  TV+C      P  C    Q  + CC  C 
Sbjct: 237 SCLFRSDVYDNGSSFL--YDN-CTACTCRDSTVVCKRKCSHPGGCD---QGQEGCCEECL 290

Query: 764 EKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEV 823
            +    D+          + C F G++ ++  G  W         I C +C C  G  E 
Sbjct: 291 LRVPPEDI----------KVCKF-GNKIFQ-DGEMW-------SSINCTICACVKGRTE- 330

Query: 824 HCEKVQC-PRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDP 863
            C   QC P  +C Q   +N   CC  C    G     GDP
Sbjct: 331 -CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDP 370



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 20/79 (25%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C FG K++   E W          + C +CAC            GR  C+N K   P  +
Sbjct: 301 CKFGNKIFQDGEMWSS--------INCTICACV----------KGRTECRN-KQCIPISS 341

Query: 111 CGQPRQLPGH-CCQTCPQE 128
           C Q + L    CC  C ++
Sbjct: 342 CPQGKILNRKGCCPICTEK 360



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 32/98 (32%), Positives = 35/98 (35%), Gaps = 30/98 (30%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGR--VSCKNIKPECP 107
           GCT+ G  Y     W     EP     CVL  C   Q G  T    R  V CKN      
Sbjct: 107 GCTYEGNTYNSSFKWQSP-AEP-----CVLRQC---QEGVVTESGVRCVVHCKN------ 151

Query: 108 TPACGQPRQLPGHCCQTCP-------QERSSSERQPSG 138
                 P +  G CC TCP       Q +   E QP G
Sbjct: 152 ------PLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG 183


>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
          Length = 456

 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 56/213 (26%), Positives = 75/213 (35%), Gaps = 68/213 (31%)

Query: 704 TCFFEGQQRPHGARWAP-----NYDP-LCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQ 757
           +C + G    HG  +       N  P  C+ C+C    V C    CP  +C  PV  PD 
Sbjct: 114 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 173

Query: 758 CCPVC------------------PEKQDVRDLPGL-----PRSRDPGEGCYFDGDRSWRA 794
           CC VC                  P  ++ R          P SR  G    F G RS R 
Sbjct: 174 CCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 233

Query: 795 A-----------------------------------GTRWHPVVPPFGLIKCAVCTCKGG 819
           A                                   G  WHP +  FG+++C +CTC   
Sbjct: 234 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--N 291

Query: 820 TGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
             +  C+K+ CP R  C  P +++   CCK CP
Sbjct: 292 VTKQECKKIHCPNRYPCKYPQKID-GKCCKVCP 323



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 46/151 (30%), Positives = 64/151 (42%), Gaps = 14/151 (9%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
           C F+ ++   G RW P  +P     C  C C     V+C  V CP   C  PV  P  CC
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96

Query: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
           P CP+      LP +  ++   + C ++G             +       +C  C+C   
Sbjct: 97  PRCPD-----SLPPV-NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC--S 148

Query: 820 TGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
            G V+C    CP+L CA PV V P  CC+ C
Sbjct: 149 EGNVYCGLKTCPKLTCAFPVSV-PDSCCRVC 178



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 31/93 (33%), Positives = 47/93 (50%), Gaps = 17/93 (18%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
           C   GK Y+  E+WHP+L   FG++ CVLC C             +  CK I   CP   
Sbjct: 260 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 306

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFE 142
            C  P+++ G CC+ CP +++   ++  G SF+
Sbjct: 307 PCKYPQKIDGKCCKVCPGKKA---KELPGQSFD 336



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 12/93 (12%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F  K Y + E WHP L EP+G++ CV C C            G V C  ++  CP   
Sbjct: 37  CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEY 143
           C  P  +P  CC  CP        + +  S EY
Sbjct: 85  CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEY 117



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 6/74 (8%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
           C   G+   HG  W PN        C LCTC      C  + CP    C +P +   +CC
Sbjct: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319

Query: 760 PVCPEKQDVRDLPG 773
            VCP K+  ++LPG
Sbjct: 320 KVCPGKK-AKELPG 332



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 4/81 (4%)

Query: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
           C F  + +   + WHP + P+G + C+ C C   G   C R  C   + C S       C
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95

Query: 929 CSRCTAHRRPAPETRTDPELE 949
           C RC     P     T    E
Sbjct: 96  CPRCPDSLPPVNNKVTSKSCE 116



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 51  CTFGGKVYALDETWHPD-LGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           C + G  Y   E +  + L +     +C  C+C            G V C  +K  CP  
Sbjct: 115 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE----------GNVYC-GLKT-CPKL 162

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
            C  P  +P  CC+ C  +   S     G  F  P  R+  H  +    +P    +A G
Sbjct: 163 TCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 221


>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 457

 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 56/213 (26%), Positives = 75/213 (35%), Gaps = 68/213 (31%)

Query: 704 TCFFEGQQRPHGARWAP-----NYDP-LCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQ 757
           +C + G    HG  +       N  P  C+ C+C    V C    CP  +C  PV  PD 
Sbjct: 114 SCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGNVYCGLKTCPKLTCAFPVSVPDS 173

Query: 758 CCPVC------------------PEKQDVRDLPGL-----PRSRDPGEGCYFDGDRSWRA 794
           CC VC                  P  ++ R          P SR  G    F G RS R 
Sbjct: 174 CCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGGLSRFPGARSHRG 233

Query: 795 A-----------------------------------GTRWHPVVPPFGLIKCAVCTCKGG 819
           A                                   G  WHP +  FG+++C +CTC   
Sbjct: 234 ALMDSQQASGTIVQIVINNKHKHGQVCVSNGKTYSHGESWHPNLRAFGIVECVLCTC--N 291

Query: 820 TGEVHCEKVQCP-RLACAQPVRVNPTDCCKQCP 851
             +  C+K+ CP R  C  P +++   CCK CP
Sbjct: 292 VTKQECKKIHCPNRYPCKYPQKID-GKCCKVCP 323



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 46/151 (30%), Positives = 64/151 (42%), Gaps = 14/151 (9%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCC 759
           C F+ ++   G RW P  +P     C  C C     V+C  V CP   C  PV  P  CC
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIPHLCC 96

Query: 760 PVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGG 819
           P CP+      LP +  ++   + C ++G             +       +C  C+C   
Sbjct: 97  PRCPD-----SLPPV-NNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC--S 148

Query: 820 TGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
            G V+C    CP+L CA PV V P  CC+ C
Sbjct: 149 EGNVYCGLKTCPKLTCAFPVSV-PDSCCRVC 178



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 14/84 (16%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP- 109
           C   GK Y+  E+WHP+L   FG++ CVLC C             +  CK I   CP   
Sbjct: 260 CVSNGKTYSHGESWHPNL-RAFGIVECVLCTCNVT----------KQECKKI--HCPNRY 306

Query: 110 ACGQPRQLPGHCCQTCPQERSSSE 133
            C  P+++ G CC+ CP +++  E
Sbjct: 307 PCKYPQKIDGKCCKVCPGKKAKEE 330



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 12/93 (12%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F  K Y + E WHP L EP+G++ CV C C            G V C  ++  CP   
Sbjct: 37  CMFQDKKYRVGERWHPYL-EPYGLVYCVNCICSEN---------GNVLCSRVR--CPNVH 84

Query: 111 CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEY 143
           C  P  +P  CC  CP        + +  S EY
Sbjct: 85  CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEY 117



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 705 CFFEGQQRPHGARWAPNYDPL----CSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCC 759
           C   G+   HG  W PN        C LCTC      C  + CP    C +P +   +CC
Sbjct: 260 CVSNGKTYSHGESWHPNLRAFGIVECVLCTCNVTKQECKKIHCPNRYPCKYPQKIDGKCC 319

Query: 760 PVCPEKQDVRDLPG 773
            VCP K+   +LPG
Sbjct: 320 KVCPGKKAKEELPG 333



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 4/81 (4%)

Query: 872 CRFAGQWFPESQSWHPSVPPFGEMSCITCRCGA-GVPHCERDDCSLPLSCGSGKE--SRC 928
           C F  + +   + WHP + P+G + C+ C C   G   C R  C   + C S       C
Sbjct: 37  CMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCP-NVHCLSPVHIPHLC 95

Query: 929 CSRCTAHRRPAPETRTDPELE 949
           C RC     P     T    E
Sbjct: 96  CPRCPDSLPPVNNKVTSKSCE 116



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 29/119 (24%), Positives = 43/119 (36%), Gaps = 15/119 (12%)

Query: 51  CTFGGKVYALDETWHPD-LGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           C + G  Y   E +  + L +     +C  C+C            G V C  +K  CP  
Sbjct: 115 CEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSE----------GNVYC-GLKT-CPKL 162

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYP--RDPEHRSYSDRGEPGAEERARG 166
            C  P  +P  CC+ C  +   S     G  F  P  R+  H  +    +P    +A G
Sbjct: 163 TCAFPVSVPDSCCRVCRGDGELSWEHSDGDIFRQPANREARHSYHRSHYDPPPSRQAGG 221


>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
          Length = 763

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 63/246 (25%), Positives = 89/246 (36%), Gaps = 51/246 (20%)

Query: 676 SAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRT 735
           SA   +  G   L P+ P   G       C  EG  + +G  W    D  CS+C+C+   
Sbjct: 564 SACINLAGGFDCLCPSGPSCSG------DCPHEGGLKHNGQVWTLKEDR-CSVCSCKDGK 616

Query: 736 VICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAA 795
           + C    C    C +P  A   CCP C  +   + L         G   Y  GD +W  +
Sbjct: 617 IFCRRTAC---DCQNP-SADLFCCPECDTRVTSQCLD------QNGHKLYRSGD-NWTHS 665

Query: 796 GTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSG 855
                          C  C C    GEV C  + CP L+C +   +   +CC +C     
Sbjct: 666 ---------------CQQCRCL--EGEVDCWPLTCPNLSC-EYTAILEGECCPRCV---- 703

Query: 856 AHPQLGDPMQADGPRGCRFA-GQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC 914
           + P L D +  D  + C  + G        W  +  P     C TC+C  G     R  C
Sbjct: 704 SDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSP-----CTTCKCKNG-----RVCC 753

Query: 915 SLPLSC 920
           S+   C
Sbjct: 754 SVDFEC 759



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 58/184 (31%)

Query: 726 CSLCTCQRRTVICDPVVCPPPSCPH---PVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGE 782
           C  CTC+   V C  + CPP +C     PV    QCC VC  K                 
Sbjct: 292 CRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPK----------------- 334

Query: 783 GCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVN 842
            C + G     A G R         ++  +   C+GG      E   CP L C++   + 
Sbjct: 335 -CIYGG--KVLAEGQR---------ILTKSCRECRGGVLVKITE--MCPPLNCSEKDHIL 380

Query: 843 P-TDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCR 901
           P   CC+ C          G    A+GP+     G+   E ++W+            TC 
Sbjct: 381 PENQCCRVC---------RGHNFCAEGPK----CGE-NSECKNWNTKA---------TCE 417

Query: 902 CGAG 905
           C +G
Sbjct: 418 CKSG 421



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 38/132 (28%)

Query: 811 CAVCTCKGGTGEVHCEKVQCPRLACAQ---PVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  CTCK G   V C ++ CP L C+    PV +    CCK C       P+        
Sbjct: 292 CRNCTCKSGA--VECRRMSCPPLNCSPDSLPVHI-AGQCCKVC------RPK-------- 334

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG---- 923
               C + G+   E Q            SC  CR G  V   E   C  PL+C       
Sbjct: 335 ----CIYGGKVLAEGQR-------ILTKSCRECRGGVLVKITEM--CP-PLNCSEKDHIL 380

Query: 924 KESRCCSRCTAH 935
            E++CC  C  H
Sbjct: 381 PENQCCRVCRGH 392


>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
          Length = 810

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 63/246 (25%), Positives = 89/246 (36%), Gaps = 51/246 (20%)

Query: 676 SAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRT 735
           SA   +  G   L P+ P   G       C  EG  + +G  W    D  CS+C+C+   
Sbjct: 611 SACINLAGGFDCLCPSGPSCSG------DCPHEGGLKHNGQVWTLKEDR-CSVCSCKDGK 663

Query: 736 VICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAA 795
           + C    C    C +P  A   CCP C  +   + L         G   Y  GD +W  +
Sbjct: 664 IFCRRTAC---DCQNP-SADLFCCPECDTRVTSQCLD------QNGHKLYRSGD-NWTHS 712

Query: 796 GTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSG 855
                          C  C C    GEV C  + CP L+C +   +   +CC +C     
Sbjct: 713 ---------------CQQCRCL--EGEVDCWPLTCPNLSC-EYTAILEGECCPRCV---- 750

Query: 856 AHPQLGDPMQADGPRGCRFA-GQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDC 914
           + P L D +  D  + C  + G        W  +  P     C TC+C  G     R  C
Sbjct: 751 SDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSP-----CTTCKCKNG-----RVCC 800

Query: 915 SLPLSC 920
           S+   C
Sbjct: 801 SVDFEC 806



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 46/184 (25%), Positives = 65/184 (35%), Gaps = 58/184 (31%)

Query: 726 CSLCTCQRRTVICDPVVCPPPSCPH---PVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGE 782
           C  CTC+   V C  + CPP +C     PV    QCC VC  K                 
Sbjct: 292 CRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPK----------------- 334

Query: 783 GCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVN 842
            C + G     A G R         ++  +   C+GG      E   CP L C++   + 
Sbjct: 335 -CIYGG--KVLAEGQR---------ILTKSCRECRGGVLVKITE--MCPPLNCSEKDHIL 380

Query: 843 P-TDCCKQCPVGSGAHPQLGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCR 901
           P   CC+ C          G    A+GP+     G+   E ++W+            TC 
Sbjct: 381 PENQCCRVC---------RGHNFCAEGPK----CGE-NSECKNWNTKA---------TCE 417

Query: 902 CGAG 905
           C +G
Sbjct: 418 CKSG 421



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 38/132 (28%)

Query: 811 CAVCTCKGGTGEVHCEKVQCPRLACAQ---PVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  CTCK G   V C ++ CP L C+    PV +    CCK C       P+        
Sbjct: 292 CRNCTCKSGA--VECRRMSCPPLNCSPDSLPVHI-AGQCCKVC------RPK-------- 334

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSG---- 923
               C + G+   E Q            SC  CR G  V   E   C  PL+C       
Sbjct: 335 ----CIYGGKVLAEGQR-------ILTKSCRECRGGVLVKITEM--CP-PLNCSEKDHIL 380

Query: 924 KESRCCSRCTAH 935
            E++CC  C  H
Sbjct: 381 PENQCCRVCRGH 392


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 694 GGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQ 753
           GGP + R+ + C+ +G+       W  +    C+ CTC++   IC  + CPP +C  P  
Sbjct: 309 GGPPKTRNMSACWQDGRFFAENETWVVDS---CTTCTCKKFKTICHQITCPPATCASPSF 365

Query: 754 APDQCCPVCPEKQD 767
              +CCP C    D
Sbjct: 366 VEGECCPSCLHSVD 379



 Score = 37.0 bits (84), Expect = 0.088
 Identities = 22/84 (26%), Positives = 30/84 (35%), Gaps = 20/84 (23%)

Query: 42  PLPVRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKN 101
           P   R  + C   G+ +A +ETW  D         C  C C+            +  C  
Sbjct: 311 PPKTRNMSACWQDGRFFAENETWVVD--------SCTTCTCKK----------FKTICHQ 352

Query: 102 IKPECPTPACGQPRQLPGHCCQTC 125
           I   CP   C  P  + G CC +C
Sbjct: 353 IT--CPPATCASPSFVEGECCPSC 374



 Score = 34.7 bits (78), Expect = 0.44
 Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 10/75 (13%)

Query: 860 LGDPMQADGPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLS 919
           +G P +      C   G++F E+++W          SC TC C      C +  C  P +
Sbjct: 308 IGGPPKTRNMSACWQDGRFFAENETWVVD-------SCTTCTCKKFKTICHQITCP-PAT 359

Query: 920 CGSGK--ESRCCSRC 932
           C S    E  CC  C
Sbjct: 360 CASPSFVEGECCPSC 374



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)

Query: 811 CAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
           C  CTCK    +  C ++ CP   CA P  V   +CC  C
Sbjct: 338 CTTCTCK--KFKTICHQITCPPATCASPSFVE-GECCPSC 374


>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
          Length = 839

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 45/163 (27%), Positives = 65/163 (39%), Gaps = 39/163 (23%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C  +G+ + +G  W    D  CS+C+CQ   V+C  +VC    C +P      CCP C  
Sbjct: 663 CIHDGKVKHNGQIWVLENDR-CSVCSCQNGFVMCRRMVC---DCENPT-VDLFCCPECDP 717

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
           +   + L         GE  Y  GD +W               +  C  C C    GEV 
Sbjct: 718 RLSSQCL------HQNGETLYNSGD-TW---------------VQNCQQCRCL--QGEVD 753

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  + CP + C   + +   +CC +C         + DP QAD
Sbjct: 754 CWPLPCPDVECEFSI-LPENECCPRC---------VTDPCQAD 786



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 36/153 (23%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHP---VQAPDQCCP 760
           TC  +G        W       C  CTC   T+ C+ ++CP P CP          +CC 
Sbjct: 296 TCTMKGTTYREFESWIDG----CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCK 351

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDGDRS--WRAAGTRWHPVVPPFGLIKCAVCTCKG 818
            C   + +    G           YF+G+R+  + ++G              C +  CK 
Sbjct: 352 EC---KSICQFQG---------RTYFEGERNTVYSSSGV-------------CVLYECKD 386

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPT-DCCKQC 850
            T ++  E   CP L C +  ++  +  CCK C
Sbjct: 387 QTMKL-VESSGCPALDCPESHQITLSHSCCKVC 418



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 699 PRDPNTCFFEGQQRPH--GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD 756
           PR  + C  +  +  +  G  W  N    C  C C +  V C P+ CP   C   +   +
Sbjct: 717 PRLSSQCLHQNGETLYNSGDTWVQN----CQQCRCLQGEVDCWPLPCPDVECEFSILPEN 772

Query: 757 QCCPVC---PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAV 813
           +CCP C   P + D           D      F G  SW   GT            +C +
Sbjct: 773 ECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGS-SWIKHGT------------ECTL 819

Query: 814 CTCKGG 819
           C CK G
Sbjct: 820 CQCKNG 825



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 44/145 (30%)

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCP--VGSGAHPQLGDPMQAD 867
           +C+VC+C+ G        V C R+ C          CC +C   + S    Q G+ +   
Sbjct: 682 RCSVCSCQNGF-------VMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNS 734

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK--- 924
           G               +W          +C  CRC  G   C       PL C   +   
Sbjct: 735 G--------------DTW--------VQNCQQCRCLQGEVDC------WPLPCPDVECEF 766

Query: 925 ----ESRCCSRCTAHRRPAPETRTD 945
               E+ CC RC      A   R D
Sbjct: 767 SILPENECCPRCVTDPCQADTIRND 791


>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
          Length = 815

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 45/163 (27%), Positives = 65/163 (39%), Gaps = 39/163 (23%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C  +G+ + +G  W    D  CS+C+CQ   V+C  +VC    C +P      CCP C  
Sbjct: 639 CIHDGKVKHNGQIWVLENDR-CSVCSCQNGFVMCRRMVC---DCENPT-VDLFCCPECDP 693

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
           +   + L         GE  Y  GD +W               +  C  C C    GEV 
Sbjct: 694 RLSSQCL------HQNGETLYNSGD-TW---------------VQNCQQCRCL--QGEVD 729

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  + CP + C   + +   +CC +C         + DP QAD
Sbjct: 730 CWPLPCPDVECEFSI-LPENECCPRC---------VTDPCQAD 762



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 36/153 (23%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHP---VQAPDQCCP 760
           TC  +G        W       C  CTC   T+ C+ ++CP P CP          +CC 
Sbjct: 272 TCTMKGTTYREFESWIDG----CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCK 327

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDGDRS--WRAAGTRWHPVVPPFGLIKCAVCTCKG 818
            C   + +    G           YF+G+R+  + ++G              C +  CK 
Sbjct: 328 EC---KSICQFQG---------RTYFEGERNTVYSSSGV-------------CVLYECKD 362

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPT-DCCKQC 850
            T ++  E   CP L C +  ++  +  CCK C
Sbjct: 363 QTMKL-VESSGCPALDCPESHQITLSHSCCKVC 394



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 699 PRDPNTCFFEGQQRPH--GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD 756
           PR  + C  +  +  +  G  W  N    C  C C +  V C P+ CP   C   +   +
Sbjct: 693 PRLSSQCLHQNGETLYNSGDTWVQN----CQQCRCLQGEVDCWPLPCPDVECEFSILPEN 748

Query: 757 QCCPVC---PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAV 813
           +CCP C   P + D           D      F G  SW   GT            +C +
Sbjct: 749 ECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGS-SWIKHGT------------ECTL 795

Query: 814 CTCKGG 819
           C CK G
Sbjct: 796 CQCKNG 801



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 44/145 (30%)

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCP--VGSGAHPQLGDPMQAD 867
           +C+VC+C+ G        V C R+ C          CC +C   + S    Q G+ +   
Sbjct: 658 RCSVCSCQNGF-------VMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNS 710

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK--- 924
           G               +W          +C  CRC  G   C       PL C   +   
Sbjct: 711 G--------------DTW--------VQNCQQCRCLQGEVDC------WPLPCPDVECEF 742

Query: 925 ----ESRCCSRCTAHRRPAPETRTD 945
               E+ CC RC      A   R D
Sbjct: 743 SILPENECCPRCVTDPCQADTIRND 767


>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 45/163 (27%), Positives = 65/163 (39%), Gaps = 39/163 (23%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C  +G+ + +G  W    D  CS+C+CQ   V+C  +VC    C +P      CCP C  
Sbjct: 640 CIHDGKVKHNGQIWVLENDR-CSVCSCQNGFVMCRRMVC---DCENPT-VDLFCCPECDP 694

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
           +   + L         GE  Y  GD +W               +  C  C C    GEV 
Sbjct: 695 RLSSQCL------HQNGETLYNSGD-TW---------------VQNCQQCRCL--QGEVD 730

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  + CP + C   + +   +CC +C         + DP QAD
Sbjct: 731 CWPLPCPDVECEFSI-LPENECCPRC---------VTDPCQAD 763



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 36/153 (23%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHP---VQAPDQCCP 760
           TC  +G        W       C  CTC   T+ C+ ++CP P CP          +CC 
Sbjct: 273 TCTMKGTTYREFESWIDG----CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCK 328

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDGDRS--WRAAGTRWHPVVPPFGLIKCAVCTCKG 818
            C   + +    G           YF+G+R+  + ++G              C +  CK 
Sbjct: 329 EC---KSICQFQG---------RTYFEGERNTVYSSSGV-------------CVLYECKD 363

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPT-DCCKQC 850
            T ++  E   CP L C +  ++  +  CCK C
Sbjct: 364 QTMKL-VESSGCPALDCPESHQITLSHSCCKVC 395



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 699 PRDPNTCFFEGQQRPH--GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD 756
           PR  + C  +  +  +  G  W  N    C  C C +  V C P+ CP   C   +   +
Sbjct: 694 PRLSSQCLHQNGETLYNSGDTWVQN----CQQCRCLQGEVDCWPLPCPDVECEFSILPEN 749

Query: 757 QCCPVC---PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAV 813
           +CCP C   P + D           D      F G  SW   GT            +C +
Sbjct: 750 ECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGS-SWIKHGT------------ECTL 796

Query: 814 CTCKGG 819
           C CK G
Sbjct: 797 CQCKNG 802



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 44/145 (30%)

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCP--VGSGAHPQLGDPMQAD 867
           +C+VC+C+ G        V C R+ C          CC +C   + S    Q G+ +   
Sbjct: 659 RCSVCSCQNGF-------VMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNS 711

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK--- 924
           G               +W          +C  CRC  G   C       PL C   +   
Sbjct: 712 G--------------DTW--------VQNCQQCRCLQGEVDC------WPLPCPDVECEF 743

Query: 925 ----ESRCCSRCTAHRRPAPETRTD 945
               E+ CC RC      A   R D
Sbjct: 744 SILPENECCPRCVTDPCQADTIRND 768


>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
          Length = 866

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 45/163 (27%), Positives = 65/163 (39%), Gaps = 39/163 (23%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C  +G+ + +G  W    D  CS+C+CQ   V+C  +VC    C +P      CCP C  
Sbjct: 690 CIHDGKVKHNGQIWVLENDR-CSVCSCQNGFVMCRRMVC---DCENPT-VDLFCCPECDP 744

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
           +   + L         GE  Y  GD +W               +  C  C C    GEV 
Sbjct: 745 RLSSQCL------HQNGETLYNSGD-TW---------------VQNCQQCRCL--QGEVD 780

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  + CP + C   + +   +CC +C         + DP QAD
Sbjct: 781 CWPLPCPDVECEFSI-LPENECCPRC---------VTDPCQAD 813



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 36/153 (23%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHP---VQAPDQCCP 760
           TC  +G        W       C  CTC   T+ C+ ++CP P CP          +CC 
Sbjct: 323 TCTMKGTTYREFESWIDG----CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCK 378

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDGDRS--WRAAGTRWHPVVPPFGLIKCAVCTCKG 818
            C   + +    G           YF+G+R+  + ++G              C +  CK 
Sbjct: 379 EC---KSICQFQG---------RTYFEGERNTVYSSSGV-------------CVLYECKD 413

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPT-DCCKQC 850
            T ++  E   CP L C +  ++  +  CCK C
Sbjct: 414 QTMKL-VESSGCPALDCPESHQITLSHSCCKVC 445



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 699 PRDPNTCFFEGQQRPH--GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD 756
           PR  + C  +  +  +  G  W  N    C  C C +  V C P+ CP   C   +   +
Sbjct: 744 PRLSSQCLHQNGETLYNSGDTWVQN----CQQCRCLQGEVDCWPLPCPDVECEFSILPEN 799

Query: 757 QCCPVC---PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAV 813
           +CCP C   P + D           D      F G  SW   GT            +C +
Sbjct: 800 ECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGS-SWIKHGT------------ECTL 846

Query: 814 CTCKGG 819
           C CK G
Sbjct: 847 CQCKNG 852



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 44/145 (30%)

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCP--VGSGAHPQLGDPMQAD 867
           +C+VC+C+ G        V C R+ C          CC +C   + S    Q G+ +   
Sbjct: 709 RCSVCSCQNGF-------VMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNS 761

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK--- 924
           G               +W          +C  CRC  G   C       PL C   +   
Sbjct: 762 G--------------DTW--------VQNCQQCRCLQGEVDC------WPLPCPDVECEF 793

Query: 925 ----ESRCCSRCTAHRRPAPETRTD 945
               E+ CC RC      A   R D
Sbjct: 794 SILPENECCPRCVTDPCQADTIRND 818


>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
          Length = 816

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 45/163 (27%), Positives = 65/163 (39%), Gaps = 39/163 (23%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPE 764
           C  +G+ + +G  W    D  CS+C+CQ   V+C  +VC    C +P      CCP C  
Sbjct: 640 CIHDGKVKHNGQIWVLENDR-CSVCSCQNGFVMCRRMVC---DCENPT-VDLFCCPECDP 694

Query: 765 KQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVH 824
           +   + L         GE  Y  GD +W               +  C  C C    GEV 
Sbjct: 695 RLSSQCL------HQNGETLYNSGD-TW---------------VQNCQQCRCL--QGEVD 730

Query: 825 CEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQAD 867
           C  + CP + C   + +   +CC +C         + DP QAD
Sbjct: 731 CWPLPCPDVECEFSI-LPENECCPRC---------VTDPCQAD 763



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 36/153 (23%)

Query: 704 TCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHP---VQAPDQCCP 760
           TC  +G        W       C  CTC   T+ C+ ++CP P CP          +CC 
Sbjct: 273 TCTMKGTTYREFESWIDG----CKNCTCLNGTIQCETLICPNPDCPLKSALAYVDGKCCK 328

Query: 761 VCPEKQDVRDLPGLPRSRDPGEGCYFDGDRS--WRAAGTRWHPVVPPFGLIKCAVCTCKG 818
            C   + +    G           YF+G+R+  + ++G              C +  CK 
Sbjct: 329 EC---KSICQFQG---------RTYFEGERNTVYSSSGV-------------CVLYECKD 363

Query: 819 GTGEVHCEKVQCPRLACAQPVRVNPT-DCCKQC 850
            T ++  E   CP L C +  ++  +  CCK C
Sbjct: 364 QTMKL-VESSGCPALDCPESHQITLSHSCCKVC 395



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 22/126 (17%)

Query: 699 PRDPNTCFFEGQQRPH--GARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPD 756
           PR  + C  +  +  +  G  W  N    C  C C +  V C P+ CP   C   +   +
Sbjct: 694 PRLSSQCLHQNGETLYNSGDTWVQN----CQQCRCLQGEVDCWPLPCPDVECEFSILPEN 749

Query: 757 QCCPVC---PEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAV 813
           +CCP C   P + D           D      F G  SW   GT            +C +
Sbjct: 750 ECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGS-SWIKHGT------------ECTL 796

Query: 814 CTCKGG 819
           C CK G
Sbjct: 797 CQCKNG 802



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 44/145 (30%)

Query: 810 KCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCP--VGSGAHPQLGDPMQAD 867
           +C+VC+C+ G        V C R+ C          CC +C   + S    Q G+ +   
Sbjct: 659 RCSVCSCQNGF-------VMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQNGETLYNS 711

Query: 868 GPRGCRFAGQWFPESQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLPLSCGSGK--- 924
           G               +W          +C  CRC  G   C       PL C   +   
Sbjct: 712 G--------------DTW--------VQNCQQCRCLQGEVDC------WPLPCPDVECEF 743

Query: 925 ----ESRCCSRCTAHRRPAPETRTD 945
               E+ CC RC      A   R D
Sbjct: 744 SILPENECCPRCVTDPCQADTIRND 768


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 39/124 (31%), Positives = 53/124 (42%), Gaps = 14/124 (11%)

Query: 683 PGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVV 742
           PG+ +     PG  G       C  +G    + A W+P  +P C+ C C    V+CD  +
Sbjct: 87  PGVESSYNVLPGKKGH------CLVKGITMYNKAVWSP--EP-CTTCLCSDGRVLCDETM 137

Query: 743 CPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGCYFDGDRSWRAAGTR-WHP 801
           C P  CP  V    +CCPVC        L G+  + D  E   F GD S +   T   H 
Sbjct: 138 CHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALN-DRNE---FSGDSSEQREPTNLLHK 193

Query: 802 VVPP 805
            +PP
Sbjct: 194 QLPP 197


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 709  GQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQ 766
            G+   +  +W  +    C++C C+   V C    CPP +C  PV  P  CCPVC +K+
Sbjct: 1420 GESHANNTKWKKD---ACTICECKDGQVTCFVEACPPATCAVPVNIPGACCPVCLQKR 1474



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 22/80 (27%), Positives = 33/80 (41%), Gaps = 20/80 (25%)

Query: 54   GGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPACGQ 113
            GG+ +A +  W  D         C +C C+           G+V+C      CP   C  
Sbjct: 1419 GGESHANNTKWKKDA--------CTICECK----------DGQVTC--FVEACPPATCAV 1458

Query: 114  PRQLPGHCCQTCPQERSSSE 133
            P  +PG CC  C Q+R+  +
Sbjct: 1459 PVNIPGACCPVCLQKRAEEK 1478



 Score = 37.0 bits (84), Expect = 0.088
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 811  CAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQC 850
            C +C CK G  +V C    CP   CA PV + P  CC  C
Sbjct: 1434 CTICECKDG--QVTCFVEACPPATCAVPVNI-PGACCPVC 1470


>gi|38348414 von Willebrand factor C domain containing 2 [Homo
           sapiens]
          Length = 325

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 39/141 (27%), Positives = 52/141 (36%), Gaps = 32/141 (22%)

Query: 715 GARWAPNYDPLCSLCTCQRRTVICDPVVCPP--PSCPHPVQAPDQCCPVCPEKQDVRDLP 772
           G ++AP   P    C C     +C    CP   P C H   +  QCCP C E+++     
Sbjct: 166 GEKFAPG--PSACPCLCTEEGPLCAQPECPRLHPRCIHVDTS--QCCPQCKERKNY---- 217

Query: 773 GLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPR 832
                      C F G         + +  +  F +  C  C C+   GEV C    CP+
Sbjct: 218 -----------CEFRG---------KTYQTLEEFVVSPCERCRCEAN-GEVLCTVSACPQ 256

Query: 833 LACAQPVRVNPTDCCKQCPVG 853
             C  PV   P  CC  C  G
Sbjct: 257 TECVDPV-YEPDQCCPICKNG 276



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 27/114 (23%)

Query: 726 CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGC 784
           C  C C+    V+C    CP   C  PV  PDQCCP+C                  G  C
Sbjct: 236 CERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN----------------GPNC 279

Query: 785 YFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEK-VQCPRLACAQ 837
           +         A T   P        +C +C C    G    E+   C R  C Q
Sbjct: 280 F---------AETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQ 324



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 24/75 (32%), Positives = 24/75 (32%), Gaps = 19/75 (25%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C F GK Y           E F V  C  C CEA          G V C      CP   
Sbjct: 218 CEFRGKTY--------QTLEEFVVSPCERCRCEAN---------GEVLCT--VSACPQTE 258

Query: 111 CGQPRQLPGHCCQTC 125
           C  P   P  CC  C
Sbjct: 259 CVDPVYEPDQCCPIC 273


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 73/266 (27%), Positives = 89/266 (33%), Gaps = 73/266 (27%)

Query: 708  EGQQRPHGARWAPNYDPLCSLCTC-QRRTVICDPVVCPPPSCP--------HPVQAPDQC 758
            +G Q      W P++ P C +CTC   R V C    CP    P           Q  DQC
Sbjct: 2261 DGVQHQFLEAWVPDHQP-CQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319

Query: 759  CP----VC-PEKQDVRDLP----GL-PRSRDPGE-----GCYFDGDRSWRAAGTRWHPVV 803
            CP    VC P   D+  +P    GL P   +PGE      C    +   R +     P  
Sbjct: 2320 CPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVS----PPSC 2375

Query: 804  PPFGLIKCAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDP 863
            PP  L       C        C++ +C   AC      N  +    CP+G  A     D 
Sbjct: 2376 PPHRLPTLRKTQC--------CDEYEC---AC------NCVNSTVSCPLGYLASTATND- 2417

Query: 864  MQADGPRGCRFAGQWFPESQSWHPS----VPPFGEMSCITCRC--------GAGVPHCER 911
                   GC       P+    H S    V  F E  C  C C        G  V  C +
Sbjct: 2418 ------CGCT-TTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLRVAQCSQ 2470

Query: 912  DDCSLPLSCGSG-----KESRCCSRC 932
              C    SC SG      E  CC RC
Sbjct: 2471 KPCE--DSCRSGFTYVLHEGECCGRC 2494


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 702 PNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVC-PPPSCPHPVQAPDQCCP 760
           P TC   G +      W P  +P C +C C    V+CD V+C    +CP       +CCP
Sbjct: 37  PITCVQNGLRYHDRDVWKP--EP-CRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCP 93

Query: 761 VCPE 764
           VCP+
Sbjct: 94  VCPD 97



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 811 CAVCTCKGGTGEVHCEKVQCPRLACAQPVRVNPTDCCKQCPVGSGAHPQLGDPMQADGPR 870
           C +C C  G  +V C+ V C          V   +CC  CP GS + P   +    +GP+
Sbjct: 58  CRICVCDNG--KVLCDDVICDETKNCPGAEVPEGECCPVCPDGSES-PTDQETTGVEGPK 114

Query: 871 G 871
           G
Sbjct: 115 G 115


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 700 RDPNTCFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPP-PSCPHPVQAPDQC 758
           ++  +C  +GQ+      W P  +P C +C C   TV+CD ++C     C  P     +C
Sbjct: 29  QEAGSCVQDGQRYNDKDVWKP--EP-CRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC 85

Query: 759 CPVCPEKQDVRDLPGLP----RSRDPGE 782
           CP+CP   D+    G P    +  +PG+
Sbjct: 86  CPICP--TDLATASGQPGPKGQKGEPGD 111



 Score = 35.8 bits (81), Expect = 0.20
 Identities = 36/143 (25%), Positives = 50/143 (34%), Gaps = 24/143 (16%)

Query: 45  VRGAAGCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKP 104
           V+ A  C   G+ Y   + W P   EP     C +C C+           G V C +I  
Sbjct: 28  VQEAGSCVQDGQRYNDKDVWKP---EP-----CRICVCDT----------GTVLCDDIIC 69

Query: 105 ECPTPACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPG----- 159
           E     C  P    G CC  CP + +++  QP     +            +G PG     
Sbjct: 70  E-DVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPA 128

Query: 160 AEERARGDGHTDFVALLTGPRSQ 182
            E+  RGD          GPR +
Sbjct: 129 GEQGPRGDRGDKGEKGAPGPRGR 151



 Score = 33.9 bits (76), Expect = 0.75
 Identities = 35/134 (26%), Positives = 42/134 (31%), Gaps = 21/134 (15%)

Query: 588 GPPGTPGPRRLLKGFYGSEAQGVVKDLEPELLRHLAKGMASLMITTKGSPRGELRGQVHI 647
           GPPG PGP  L   F    A G  +      L  +   M  +       P G        
Sbjct: 165 GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG-------- 216

Query: 648 ANQCEVGGLRLEAAGAEGVRAL-GAPDTASAAPPVVPGLPALAPAKPGGPGRPRDPNTCF 706
                       A G +G +   G P     + P+ P  P   P KPG  G    P    
Sbjct: 217 ------------APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 264

Query: 707 FEGQQRPHGARWAP 720
             G   P GAR  P
Sbjct: 265 ERGPPGPQGARGFP 278


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 18/47 (38%), Positives = 23/47 (48%)

Query: 726  CSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLP 772
            C+ C C+   V C   +CPP  CP P      CCPVC ++    D P
Sbjct: 1414 CTHCICESGQVTCVVEICPPAPCPSPELVKGTCCPVCRDRGMPSDSP 1460



 Score = 31.6 bits (70), Expect = 3.7
 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 21/78 (26%)

Query: 49   AGCT-FGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECP 107
            AGCT   G     +E W  +         C  C CE+          G+V+C  +   CP
Sbjct: 1393 AGCTDVRGVPRKAEERWMKE--------DCTHCICES----------GQVTC--VVEICP 1432

Query: 108  TPACGQPRQLPGHCCQTC 125
               C  P  + G CC  C
Sbjct: 1433 PAPCPSPELVKGTCCPVC 1450


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 20/112 (17%)

Query: 50  GCTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTP 109
           GC+  G+ YA  + W P   EP     C +C C++          G V C +I  +    
Sbjct: 31  GCSHLGQSYADRDVWKP---EP-----CQICVCDS----------GSVLCDDIICDDQEL 72

Query: 110 ACGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPR-DPEHRSYSDR-GEPG 159
            C  P    G CC  CPQ  ++  R P+G   + P+ DP       R G+PG
Sbjct: 73  DCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPG 124



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 5/62 (8%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPP--SCPHPVQAPDQCCPVC 762
           C   GQ       W P  +P C +C C   +V+CD ++C      CP+P     +CC VC
Sbjct: 32  CSHLGQSYADRDVWKP--EP-CQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVC 88

Query: 763 PE 764
           P+
Sbjct: 89  PQ 90


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 4/61 (6%)

Query: 705 CFFEGQQRPHGARWAPNYDPLCSLCTCQRRTVICDPVVCPPP-SCPHPVQAPDQCCPVCP 763
           C   GQ   +   W P     C +C C    ++CD + C     C  PV  P +CCPVC 
Sbjct: 41  CTQNGQMYLNRDIWKP---APCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCS 97

Query: 764 E 764
           +
Sbjct: 98  Q 98



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 13/63 (20%)

Query: 811 CAVCTCKGGTGEVHCEKVQCPR-LACAQPVRVNPTDCCKQCP---------VGSGAHPQL 860
           C +C C  G   + C+K++C   L CA PV   P +CC  C           G G   Q 
Sbjct: 59  CQICVCDNGA--ILCDKIECQDVLDCADPV-TPPGECCPVCSQTPGGGNTNFGRGRKGQK 115

Query: 861 GDP 863
           G+P
Sbjct: 116 GEP 118



 Score = 35.4 bits (80), Expect = 0.26
 Identities = 29/110 (26%), Positives = 39/110 (35%), Gaps = 32/110 (29%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           CT  G++Y   + W P          C +C C+           G + C  I  EC    
Sbjct: 41  CTQNGQMYLNRDIWKP--------APCQICVCDN----------GAILCDKI--ECQDVL 80

Query: 111 -CGQPRQLPGHCCQTCPQERSSSERQPSGLSFEYPRDPEHRSYSDRGEPG 159
            C  P   PG CC  C Q        P G +  + R  +      +GEPG
Sbjct: 81  DCADPVTPPGECCPVCSQ-------TPGGGNTNFGRGRK----GQKGEPG 119



 Score = 30.4 bits (67), Expect = 8.2
 Identities = 43/147 (29%), Positives = 53/147 (36%), Gaps = 14/147 (9%)

Query: 588 GPPGTPGPR--RLLKGFYGSEAQ-------GVVKDLEPE-LLRHLAKGMASLMITTK-GS 636
           GP G PGPR  + + G  G   Q       G      P+ L R  +  MA L   +  GS
Sbjct: 147 GPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGS 206

Query: 637 PRGELRGQVHIANQCEVGGLRLEAAGAEGVRALGAPDTASAAPPVVPGLPALAPAKPG-- 694
             G + G V         GL+ +  GA      G P       P+    P   P KPG  
Sbjct: 207 QVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266

Query: 695 -GPGRPRDPNTCFFEGQQRPHGARWAP 720
             PGR  +P    F G     G   AP
Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAP 293



 Score = 30.4 bits (67), Expect = 8.2
 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 7/58 (12%)

Query: 662 GAEGVRALGAPDTA----SAAPPVVPGLPALAPAKPGGPGRPRDPNTCFFEGQQRPHG 715
           GA+G    G+P T+    SA PP  PG P  +    G  G+P DP    F+G+  P G
Sbjct: 429 GAKG--PTGSPGTSGPPGSAGPPGSPG-PQGSTGPQGIRGQPGDPGVPGFKGEAGPKG 483


>gi|122937446 von Willebrand factor C domain-containing protein
           2-like [Homo sapiens]
          Length = 222

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 28/108 (25%)

Query: 726 CSLCTCQ-RRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGC 784
           C  C C+    V C    C  P C +PV  P+QCCPVC                  G  C
Sbjct: 134 CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKN----------------GPNC 177

Query: 785 YFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGT--GEVHCEKVQC 830
           +         AGT   P      + +C +C C  G       C K +C
Sbjct: 178 F---------AGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 36/143 (25%)

Query: 715 GARWAPNYDPLCSLCTCQRRTVIC--DPVVCPPPSCP--HPVQAPDQCCPVCPEKQDVRD 770
           G R+ P +    S C C     +C  D  VC  P CP  HP     +    CPE ++V++
Sbjct: 64  GERFFPGH----SNCPC-----VCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114

Query: 771 LPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQC 830
                        C + G           + ++  F    C  C C+  + EVHC    C
Sbjct: 115 F------------CEYHGKN---------YKILEEFKPSPCEWCRCEP-SNEVHCVVADC 152

Query: 831 PRLACAQPVRVNPTDCCKQCPVG 853
               C  PV   P  CC  C  G
Sbjct: 153 AVPECVNPV-YEPEQCCPVCKNG 174



 Score = 30.8 bits (68), Expect = 6.3
 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 19/75 (25%)

Query: 51  CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
           C + GK Y + E + P          C  C CE             V C  +  +C  P 
Sbjct: 116 CEYHGKNYKILEEFKPS--------PCEWCRCEPSN---------EVHC--VVADCAVPE 156

Query: 111 CGQPRQLPGHCCQTC 125
           C  P   P  CC  C
Sbjct: 157 CVNPVYEPEQCCPVC 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,267,771
Number of Sequences: 37866
Number of extensions: 2849776
Number of successful extensions: 13349
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 11036
Number of HSP's gapped (non-prelim): 2131
length of query: 955
length of database: 18,247,518
effective HSP length: 112
effective length of query: 843
effective length of database: 14,006,526
effective search space: 11807501418
effective search space used: 11807501418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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