BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|30089954 H326 [Homo sapiens] (597 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|30089954 H326 [Homo sapiens] 1224 0.0 gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 845 0.0 gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] 795 0.0 gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 145 8e-35 gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 145 8e-35 gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 134 3e-31 gi|55741849 WD repeat domain 22 [Homo sapiens] 99 8e-21 gi|16554629 WD repeat domain 5 [Homo sapiens] 74 5e-13 gi|16554627 WD repeat domain 5 [Homo sapiens] 74 5e-13 gi|23199987 WD repeat domain 5B [Homo sapiens] 66 1e-10 gi|147904340 WD repeat domain 82 [Homo sapiens] 62 2e-09 gi|19913369 transducin beta-like 3 [Homo sapiens] 57 5e-08 gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 57 6e-08 gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 57 6e-08 gi|7706657 cell division cycle 40 homolog [Homo sapiens] 53 7e-07 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 53 9e-07 gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 52 1e-06 gi|113865883 WD repeat domain 38 [Homo sapiens] 51 3e-06 gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 51 3e-06 gi|8922301 WD repeat domain 70 [Homo sapiens] 51 3e-06 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 50 5e-06 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 50 5e-06 gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 49 2e-05 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 48 2e-05 gi|156104891 general transcription factor IIF, polypeptide 1, 74... 48 3e-05 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 47 5e-05 gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 47 5e-05 gi|21735415 centromere protein B [Homo sapiens] 47 7e-05 gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 47 7e-05 gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 47 7e-05 >gi|30089954 H326 [Homo sapiens] Length = 597 Score = 1224 bits (3166), Expect = 0.0 Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT Sbjct: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR Sbjct: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 Query: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV Sbjct: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180 Query: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF Sbjct: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240 Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL Sbjct: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300 Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD Sbjct: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360 Query: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD Sbjct: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420 Query: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV Sbjct: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480 Query: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF Sbjct: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540 Query: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS Sbjct: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597 >gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapiens] Length = 631 Score = 845 bits (2183), Expect = 0.0 Identities = 426/632 (67%), Positives = 489/632 (77%), Gaps = 36/632 (5%) Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD-----DG 55 MS + STDG DL SL SSPEE SGA E SS I++ S+LS+++TGD DG Sbjct: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60 Query: 56 G-PNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVH------------------ 96 G PN STE+R +D ES+ ED + +S+ED H+ ++ E+ H Sbjct: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120 Query: 97 -----------DRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145 + EEEEEEEEEEEEEQPR Q N +Q S ++++ALE+WVSSETS Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180 Query: 146 ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRG 205 ALPRPRWQ + AL +R+LGS RFVYEACGAR FVQRFRLQ+ L H GCVNT+HFNQRG Sbjct: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240 Query: 206 TWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVA 265 T LAS DDLKV+VWDWVR++PVL+FESGH +NVFQAKFLPN GDSTLAMCARDGQVRVA Sbjct: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300 Query: 266 ELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVT 325 EL NTK VAQH+G +HKLALEPDSP FL++GEDAVVFTIDLRQDRPASK+VVT Sbjct: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360 Query: 326 KEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSE 385 +E +KKVGLYTI VNPANT+QFAVGG+DQFVRIYDQRKID+ ENNGVLKKF PHHLVN + Sbjct: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420 Query: 386 SKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGP 445 NITC+VYSHDGTELLASYND+DIYLFNSSHSDGAQY KR+KGHRNN TVKGVNFYGP Sbjct: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480 Query: 446 KSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505 +SEFVVSGSDCGHIF WEKSSCQIIQF++G + G +NCLEPHP+LPVLA SGLDHDVKIW Sbjct: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540 Query: 506 APTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPG 565 PTA+A+TELTGLK VIKKNK ERDEDSLH LFD +MLWFL+ H+ QR H+ WR Sbjct: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600 Query: 566 VGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597 D +SDES S+S+TS EEE DRVQCMPS Sbjct: 601 AEFPDEESDESSSTSETS-EEEVQDRVQCMPS 631 >gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] Length = 600 Score = 795 bits (2052), Expect = 0.0 Identities = 410/604 (67%), Positives = 474/604 (78%), Gaps = 11/604 (1%) Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD--DGG-P 57 MS + ST G DL SL SSPEE SG SS IE+ A++ S GD DGG Sbjct: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60 Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDT--GHYSINDENRVHDRSEEEEEEEEE-EEEEQP 114 N STE++ TD+ESS ED + +SM + G+ + +E +R EEEEE EEE EEEEQP Sbjct: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEET---EREEEEEEMEEEGEEEEQP 117 Query: 115 RRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEAC 174 R + N DQ D+++ALE+W+SSETSALPR RWQ L ALR+R+LGSSARFVYEAC Sbjct: 118 RMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEAC 177 Query: 175 GARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESG 234 GAR FVQRFRLQ+ L H G V+T+HFNQRGT LAS DDL+V+VWDWVR++PVL+FESG Sbjct: 178 GARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESG 237 Query: 235 HKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPD 294 H NV QAKF PN GDSTLAMC DGQVRVAEL C+NTKRVA+H+G +H+LALEPD Sbjct: 238 HDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPD 297 Query: 295 SPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQ 354 SP FL++GEDAVVFTIDLRQDRPASK+VVT+E +KKVGLYTI +NPAN +QFAVGG DQ Sbjct: 298 SPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQ 357 Query: 355 FVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLF 414 FVRIYDQR+ID+ ENNGVLKKF PHHLV + NITC+VYSHDGTELLASYNDEDIYLF Sbjct: 358 FVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLF 417 Query: 415 NSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFME 474 NSS SDGAQYVKRYKGHRNN T+K VNFYGP+SEFVVSGSDCGH+F WEKSS QIIQFME Sbjct: 418 NSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFME 477 Query: 475 GDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSL 534 GD+G +VNCLEPHP+LPVLATSGLD V+IW PTA+ +TELTGLKDVIKKNK+ERDED+L Sbjct: 478 GDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNL 537 Query: 535 HQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADS-DESPSSSDTSDEEEGPDRVQ 593 + TD FD+ ML F + HL QR H WR+ G D + DES S+SDTS EEEG DRVQ Sbjct: 538 NYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTS-EEEGQDRVQ 596 Query: 594 CMPS 597 C+PS Sbjct: 597 CIPS 600 >gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] Length = 860 Score = 145 bits (367), Expect = 8e-35 Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%) Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215 +R+R LG +R G R F+QR +L+ L H GCVNT+ +N G ++ SGSDD Sbjct: 14 VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73 Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275 K+V+ + R+ + SGH++N+F AKFLP + D + C+ DG + + Sbjct: 74 KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133 Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330 + H G ++++ P+ P TFLS GED V D R K TKE K Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188 Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380 + ++ + P + AVG D VRIYD+R + G++ +F P H Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248 Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415 L N + +T L YS DG E+L SY+ + IYLF+ Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281 Score = 105 bits (262), Expect = 1e-22 Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%) Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486 YKGHRN+ T +K NF+G + FV+SGSDCGHIF+W++ + + + +E D VVNCL+P Sbjct: 713 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 769 Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546 HP P+LA+SG+D+D+KIW+P E+ L D + E++ + + S ML Sbjct: 770 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 829 Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575 L ++H+R R R G G + + DE Sbjct: 830 MLASLNHIRADRLEGD-RSEGSGQENENEDE 859 >gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] Length = 880 Score = 145 bits (367), Expect = 8e-35 Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%) Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215 +R+R LG +R G R F+QR +L+ L H GCVNT+ +N G ++ SGSDD Sbjct: 14 VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73 Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275 K+V+ + R+ + SGH++N+F AKFLP + D + C+ DG + + Sbjct: 74 KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133 Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330 + H G ++++ P+ P TFLS GED V D R K TKE K Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188 Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380 + ++ + P + AVG D VRIYD+R + G++ +F P H Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248 Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415 L N + +T L YS DG E+L SY+ + IYLF+ Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281 Score = 105 bits (262), Expect = 1e-22 Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%) Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486 YKGHRN+ T +K NF+G + FV+SGSDCGHIF+W++ + + + +E D VVNCL+P Sbjct: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789 Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546 HP P+LA+SG+D+D+KIW+P E+ L D + E++ + + S ML Sbjct: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849 Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575 L ++H+R R R G G + + DE Sbjct: 850 MLASLNHIRADRLEGD-RSEGSGQENENEDE 879 >gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] Length = 676 Score = 134 bits (336), Expect = 3e-31 Identities = 91/309 (29%), Positives = 145/309 (46%), Gaps = 47/309 (15%) Query: 179 FVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSN 238 F++R L+ L+GH+GCVN L +N++G LASGSDD +VWD + + +L +GH +N Sbjct: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92 Query: 239 VFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298 +F KFLP++GD L A D +V V +L+ + H ++A P P T Sbjct: 93 IFSVKFLPHAGDRILITGAADSKVHVHDLTVKE---TIHMFGDHTNRVKRIATAPMWPNT 149 Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVV--TKEKEKKVGLYTIYVNPANTHQFAVGGRDQFV 356 F SA ED ++ DLR++ S++++ T+ + V + VNP + + AVG FV Sbjct: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209 Query: 357 RIYDQRKIDENEN---------------------NGVLKKFCPHHL------VNSESKAN 389 R+YD R I + +G + + HL N+ + Sbjct: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269 Query: 390 I-TCLVYSHDGTELLASYNDEDIYLFN--------------SSHSDGAQYVKRYKGHRNN 434 + T + +S +GTELL + E +YLF+ HS G Q K +N Sbjct: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329 Query: 435 ATVKGVNFY 443 G++ + Sbjct: 330 GVSNGLHLH 338 Score = 95.5 bits (236), Expect = 1e-19 Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 38/199 (19%) Query: 405 SYNDEDIYLFNSSHSDGAQYVKRYKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWE 463 S +++++ L S+ Y RY GH N T +K NF+G ++++VSGSD G F+WE Sbjct: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565 Query: 464 KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTG-----L 518 K + +++ ++GD+ +VNCL+PHP LATSG+D V++W P E S +LTG + Sbjct: 566 KETTNLVRVLQGDE-SIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDM 623 Query: 519 KDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPS 578 + + N+R + D L L + + L G GA+D Sbjct: 624 EGASQANQRRMNADPLEVMLLNMGYRITGL-------------SSGGAGASD-------- 662 Query: 579 SSDTSDEEEGPDRVQCMPS 597 DE+ +VQC PS Sbjct: 663 -----DEDSSEGQVQCRPS 676 >gi|55741849 WD repeat domain 22 [Homo sapiens] Length = 942 Score = 99.4 bits (246), Expect = 8e-21 Identities = 84/334 (25%), Positives = 156/334 (46%), Gaps = 35/334 (10%) Query: 189 LEGHTGCVNTLHF-NQRGTWLASGSDDLKVVVWDWVR----RQPVLDFESGHKSNVFQAK 243 L GH GCVN + F N G WL SG DD +V++W + R + + H SN+F Sbjct: 49 LLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLA 108 Query: 244 FLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAG 303 F NSG++ + D QV + ++ +++ T V H+ A + L++ P + F S+ Sbjct: 109 F--NSGNTKVFSGGNDEQVILHDVESSE----TLDVFAHEDAVYGLSVSPVNDNIFASSS 162 Query: 304 EDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRK 363 +D V D+R+ + +++ NP A + V ++D RK Sbjct: 163 DDGRVLIWDIRESPHGEPFCLANYPS---AFHSVMFNPVEPRLLATANSKEGVGLWDIRK 219 Query: 364 IDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQ 423 + L ++ + + S ++ +GT+LLA L++ HS Sbjct: 220 PQSS-----LLRYGGNLSLQSAMSVR-----FNSNGTQLLALRRRLPPVLYDI-HSRLPV 268 Query: 424 YVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLW----EKSSCQIIQFMEGD--- 476 + +G+ N+ T+K F G + ++++SGSD ++++W + + I + + G Sbjct: 269 FQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMV 328 Query: 477 -KG--GVVNCLEPHPHLPVLATSGLDHDVKIWAP 507 KG +VN + +PH ++ +SG++ +KIW+P Sbjct: 329 LKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSP 362 >gi|16554629 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 73.6 bits (179), Expect = 5e-13 Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%) Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239 + L+ L GHT V+++ F+ G WLAS S D + +W + FE SGHK + Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90 Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298 + S DS L + A D + +++ ++S+ +C K K Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126 Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347 G VF + P S L+V+ ++ V ++ + + +P + F Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179 Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406 G YD +I + + LK + ++ + +S +G +LA+ Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233 Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466 D + L++ S + +K Y GH+N NF +++VSGS+ +++W + Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290 Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505 +I+Q ++G V++ HP ++A++ L++D +K+W Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330 >gi|16554627 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 73.6 bits (179), Expect = 5e-13 Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%) Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239 + L+ L GHT V+++ F+ G WLAS S D + +W + FE SGHK + Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90 Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298 + S DS L + A D + +++ ++S+ +C K K Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126 Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347 G VF + P S L+V+ ++ V ++ + + +P + F Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179 Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406 G YD +I + + LK + ++ + +S +G +LA+ Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233 Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466 D + L++ S + +K Y GH+N NF +++VSGS+ +++W + Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290 Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505 +I+Q ++G V++ HP ++A++ L++D +K+W Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330 >gi|23199987 WD repeat domain 5B [Homo sapiens] Length = 330 Score = 65.9 bits (159), Expect = 1e-10 Identities = 70/328 (21%), Positives = 142/328 (43%), Gaps = 37/328 (11%) Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFES---GHKSNV 239 + L+ L GHT V+++ F+ G WLAS S D +++W + +E GH + Sbjct: 31 YALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK----YEKTLYGHNLEI 86 Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTF 299 + +S S L + D +++ ++ + +C K K H P S Sbjct: 87 SDVAW--SSDSSRLVSASDDKTLKLWDVRSGKCLKTLKG---HSNYVFCCNFNPPSNL-I 140 Query: 300 LSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIY 359 +S D V +++ + L + + ++ N + + G D RI+ Sbjct: 141 ISGSFDETVKIWEVKTGKCLKTLSAHSDP-----VSAVHFNCSGS-LIVSGSYDGLCRIW 194 Query: 360 DQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHS 419 D C LV+ ++ ++ + +S +G +L + D + L++ S Sbjct: 195 DAASGQ-----------CLKTLVDDDNPP-VSFVKFSPNGKYILTATLDNTLKLWDYSRG 242 Query: 420 DGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGG 479 + +K Y GH+N NF +++VSGS+ +++W + +I+Q ++G Sbjct: 243 ---RCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299 Query: 480 VVNCLEPHPHLPVLATSGLDHD--VKIW 505 V++ HP ++A++ L++D +K+W Sbjct: 300 VISA-ACHPTENLIASAALENDKTIKLW 326 >gi|147904340 WD repeat domain 82 [Homo sapiens] Length = 313 Score = 61.6 bits (148), Expect = 2e-09 Identities = 74/338 (21%), Positives = 131/338 (38%), Gaps = 40/338 (11%) Query: 180 VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNV 239 ++ FR+ ++ +N F+ G + S SDD +V++D +P S K V Sbjct: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYS-KKYGV 66 Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPC-- 297 ++ + + D +R L + K + G S ++ SP Sbjct: 67 DLIRYTHAANTVVYSSNKIDDTIRYLSLH------DNKYIRYFPGHSKRVVALSMSPVDD 120 Query: 298 TFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ-----FAVGGR 352 TF+S D + DLR GL + P + FA G Sbjct: 121 TFISGSLDKTIRLWDLRSPNCQ-------------GLMHLQGKPVCSFDPEGLIFAAGVN 167 Query: 353 DQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIY 412 + V++YD R D+ G F + + T L +S+DG +L S N I Sbjct: 168 SEMVKLYDLRSFDK----GPFATFKMQY----DRTCEWTGLKFSNDGKLILISTNGSFIR 219 Query: 413 LFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQF 472 L ++ + + G+ N+ V + P S+F++ GS+ G I +W S + Sbjct: 220 LIDAFKG---VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAV 276 Query: 473 MEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAE 510 ++G G + CL+ +P A++ ++ W PT + Sbjct: 277 LDGKHTGPITCLQFNPKFMTFASA--CSNMAFWLPTID 312 >gi|19913369 transducin beta-like 3 [Homo sapiens] Length = 808 Score = 57.0 bits (136), Expect = 5e-08 Identities = 78/321 (24%), Positives = 119/321 (37%), Gaps = 32/321 (9%) Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251 HT V T+ F+ T LA+G D V VWD VR F G V F P+ Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFR-GSPGVVHLVAFHPDPTRL 166 Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311 L A D +RV L C + H A LA D T LS+G D + Sbjct: 167 LLFSSATDAAIRVWSLQDRSC---LAVLTAHYSAVTSLAFSADGH-TMLSSGRDKICIIW 222 Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ----FAVGGRDQFVRIYDQRKIDEN 367 DL+ + + V + E V L V+ F G +R+++ Sbjct: 223 DLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWE------- 275 Query: 368 ENNGVLKKFCPHHLVNSESKA-NITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVK 426 C + +T +H +L + D ++ L+ + + K Sbjct: 276 ----AASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEAR---SLRLQK 328 Query: 427 RYKGHRNNATVKGVNFYGPKSEFVV--SGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCL 484 ++ G+ + V V F GP+ VV S S C +F + S+CQI+ +V L Sbjct: 329 QFAGY--SEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH----GHTDIVLAL 382 Query: 485 EPHPHLPVLATSGLDHDVKIW 505 + + A+ D V+IW Sbjct: 383 DVFRKGWLFASCAKDQSVRIW 403 Score = 37.0 bits (84), Expect = 0.052 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%) Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504 P + + +GS LW CQ++ G + G+ C++ P VLAT+ D +K+ Sbjct: 489 PNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLW-CVQFSPMDQVLATASADGTIKL 547 Query: 505 WA 506 WA Sbjct: 548 WA 549 >gi|153791298 mitogen-activated protein kinase organizer 1 [Homo sapiens] Length = 315 Score = 56.6 bits (135), Expect = 6e-08 Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%) Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253 G V + FN G + + D + +W+ +R +L SGH V A + +S+L Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82 Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313 D V + ++++ Q ++ H G + + ++ LS D+ + D Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138 Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373 R RP V E + G+ ++ V+ H+ G D VR YD R Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182 Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433 L + + ITC +S DG L S D + L + D + + YKGH+N Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234 Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493 K + VVS S+ G +F W+ + + GVV L HP P L Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292 Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517 T+ + V+ W A + + G Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%) Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223 G A +++ +V V++FR GH G VNT+ FN+ T + SGS D + WD Sbjct: 87 GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139 Query: 224 RRQP 227 R+P Sbjct: 140 SRRP 143 >gi|14150114 mitogen-activated protein kinase organizer 1 [Homo sapiens] Length = 315 Score = 56.6 bits (135), Expect = 6e-08 Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%) Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253 G V + FN G + + D + +W+ +R +L SGH V A + +S+L Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82 Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313 D V + ++++ Q ++ H G + + ++ LS D+ + D Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138 Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373 R RP V E + G+ ++ V+ H+ G D VR YD R Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182 Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433 L + + ITC +S DG L S D + L + D + + YKGH+N Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234 Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493 K + VVS S+ G +F W+ + + GVV L HP P L Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292 Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517 T+ + V+ W A + + G Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315 Score = 40.4 bits (93), Expect = 0.005 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%) Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223 G A +++ +V V++FR GH G VNT+ FN+ T + SGS D + WD Sbjct: 87 GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139 Query: 224 RRQP 227 R+P Sbjct: 140 SRRP 143 >gi|7706657 cell division cycle 40 homolog [Homo sapiens] Length = 579 Score = 53.1 bits (126), Expect = 7e-07 Identities = 92/469 (19%), Positives = 179/469 (38%), Gaps = 50/469 (10%) Query: 41 VEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE 100 VE ++ + LT + G +T + + ++S D + Y DE V SE Sbjct: 156 VEEAEKNQGLTVFETGQKKTEKRKKFKENDASNID---GFLGPWAKYV--DEKDVAKPSE 210 Query: 101 EEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRE 160 EE++E +E ++ ++ Q + ++ + + + D+ +P+ Sbjct: 211 EEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQ----------- 259 Query: 161 RELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLH-FNQRGTWLASGSDDLKVVV 219 ++G + R + ++ + ++ H GHT V+ + F G L S S D K+ + Sbjct: 260 -DVGVNLRSTMPP--EKCYLPKKQI-HVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKL 315 Query: 220 WDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN-TKR 278 W+ + L GH V F N+ + A D +++ + QC T R Sbjct: 316 WEVYGERRCLRTFIGHSKAVRDICF--NTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR 373 Query: 279 VAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIY 338 + K + D F++ D + D+R + +E ++ +G Sbjct: 374 KVPY---CVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGE------IVQEYDRHLGAVNTI 424 Query: 339 VNPANTHQFAVGGRDQFVRIYD-QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSH 397 V +F D+ +R+++ +D + S ++ + S Sbjct: 425 VFVDENRRFVSTSDDKSLRVWEWDIPVD-------------FKYIAEPSMHSMPAVTLSP 471 Query: 398 DGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCG 457 +G L D I +F + + K +KGH V+F P +V+SG G Sbjct: 472 NGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDF-SPDMSYVISGDGNG 530 Query: 458 HIFLWE-KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505 + +W+ K++ +F DK + PH V+ T G D +K+W Sbjct: 531 KLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVI-TCGWDGLIKLW 578 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 52.8 bits (125), Expect = 9e-07 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 24/167 (14%) Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDT 84 E G EG + E+ A D + G++G TES+ E+ GE K+ + + Sbjct: 801 EGKGDNEGEDEG---EIHAEDGEMK--GNEG-----ETESQELSAENHGEAKNDEKGVED 850 Query: 85 GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSET 144 G S ++ + EEE+EEEEEEEE++ + + +++ ++E DW + Sbjct: 851 GGGSDGGDSEEEEEEEEEQEEEEEEEEQEE----EEEEEEEEEEKGNEEPLSLDWPETRQ 906 Query: 145 S--------ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRF 183 + P W +P +R +E S FV+ G+ +++ F Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQE--SRKFFVFTFLGSIMWIAMF 951 >gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] Length = 446 Score = 52.4 bits (124), Expect = 1e-06 Identities = 83/356 (23%), Positives = 140/356 (39%), Gaps = 37/356 (10%) Query: 24 EEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE-----SRGTDTESSGEDKDS 78 EE+ EE + A LS + D G NRT GT ES+ ++ Sbjct: 45 EELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNR-- 102 Query: 79 DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALED 138 M H + + S+EEEEEE+EE+EE+ + +++ R Sbjct: 103 -LMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMV---PHYGGINRVRVS 158 Query: 139 WVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQ----HGLEGHTG 194 W+ E A W + L + V E F++ + Q GH G Sbjct: 159 WLGEEPVA---GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMG 215 Query: 195 CVNTLHFNQRGTW-LASGSDDLKVVVW------DW-VRRQPVLDFESGHKSNVFQAKFLP 246 L ++ R T L +G + +W W V ++P + GH +V ++ P Sbjct: 216 EGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFV----GHTRSVEDLQWSP 271 Query: 247 NSGDSTLAMCARDGQVRVAELSA--TQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE 304 ++ A C+ D +R+ ++ A ++ C T A H G + ++ P LS G+ Sbjct: 272 TE-NTVFASCSADASIRIWDIRAAPSKACMLTTATA-HDGDVNVISWSRREP-FLLSGGD 328 Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360 D + DLRQ + S + K+ V ++ +P ++ FA G D + +D Sbjct: 329 DGALKIWDLRQFKSGSPVATFKQHVAPV--TSVEWHPQDSGVFAASGADHQITQWD 382 Score = 31.2 bits (69), Expect = 2.8 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 7/74 (9%) Query: 446 KSEFVVSGSDCGHIFLWE----KSSCQIIQFMEGDKGGVVNCLEPHPH-LPVLATSGLDH 500 + F++SG D G + +W+ KS + F + V +E HP V A SG DH Sbjct: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQ--HVAPVTSVEWHPQDSGVFAASGADH 376 Query: 501 DVKIWAPTAEASTE 514 + W E E Sbjct: 377 QITQWDLAVERDPE 390 >gi|113865883 WD repeat domain 38 [Homo sapiens] Length = 314 Score = 50.8 bits (120), Expect = 3e-06 Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 32/285 (11%) Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251 H G VN+ F+ G L +GS+D V W+ R +L GH V +F P+ Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWE-TRSGQLLWRLGGHTGPVKFCRFSPDGHLF 78 Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311 A C D VR+ +++ +C + K H+ + ++ PDS S G D V Sbjct: 79 ASASC--DCTVRLWDVARAKCLRVLK---GHQRSVETVSFSPDSR-QLASGGWDKRVMLW 132 Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNG 371 D++ + LV ++ + + A G D V I+D R + ++ Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDF------SPTVNCLATGSWDSTVHIWDLRMVTPAVSHQ 186 Query: 372 VLKKFCPHHLVNSESKANITCLVYSHDGTELLASYN-DEDIYLFNSSHSDGAQYVKRYKG 430 L+ ANI+CL YS G LLAS + D+ I+++ + S + + KG Sbjct: 187 ALE----------GHSANISCLCYSASG--LLASGSWDKTIHIWKPTTS---SLLIQLKG 231 Query: 431 HRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEG 475 H VK + F P ++ S + +W+ ++ + ++ ++G Sbjct: 232 H--VTWVKSIAF-SPDELWLASAGYSRMVKVWDCNTGKCLETLKG 273 Score = 41.6 bits (96), Expect = 0.002 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%) Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248 L GHTG V F+ G AS S D V +WD V R L GH+ +V F P+S Sbjct: 59 LGGHTGPVKFCRFSPDGHLFASASCDCTVRLWD-VARAKCLRVLKGHQRSVETVSFSPDS 117 Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE-DAV 307 LA D +V + ++ + Q + + H+ + P C L+ G D+ Sbjct: 118 --RQLASGGWDKRVMLWDVQSGQM---LRLLVGHRDSIQSSDFSPTVNC--LATGSWDST 170 Query: 308 VFTIDLRQDRPA 319 V DLR PA Sbjct: 171 VHIWDLRMVTPA 182 Score = 38.9 bits (89), Expect = 0.014 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%) Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232 C R++ V R + L+GH V T+ F+ LASG D +V++WD V+ +L Sbjct: 85 CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD-VQSGQMLRLL 143 Query: 233 SGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAEL 267 GH+ ++ + F P + LA + D V + +L Sbjct: 144 VGHRDSIQSSDFSPTV--NCLATGSWDSTVHIWDL 176 Score = 35.8 bits (81), Expect = 0.11 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNC- 483 V+R K + + + P + +++GS+ G ++ WE S Q++ + G G V C Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70 Query: 484 LEPHPHLPVLATSGLDHDVKIW 505 P HL A++ D V++W Sbjct: 71 FSPDGHL--FASASCDCTVRLW 90 >gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] Length = 357 Score = 50.8 bits (120), Expect = 3e-06 Identities = 67/279 (24%), Positives = 118/279 (42%), Gaps = 32/279 (11%) Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248 L+GH+G V LH+N G+ L S S D V VWD + V + GH S V + + Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFV-NSCYPARR 162 Query: 249 GDSTLAMCARDGQVRVAEL---SATQCCKNTKRVAQHKGASHKLALE-PDSPCTFLSAGE 304 G + + DG V++ ++ +A Q +NT +V LA+ D+ +S G Sbjct: 163 GPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV---------LAVTFNDTSDQIISGGI 213 Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKI 364 D + DLRQ++ +T T + D VR++D R Sbjct: 214 DNDIKVWDLRQNK------LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPF 267 Query: 365 DENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQY 424 E K ++ N E N+ +S DG+++ A D +Y+++++ + Sbjct: 268 APKER---CVKIFQGNVHNFEK--NLLRCSWSPDGSKIAAGSADRFVYVWDTT---SRRI 319 Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWE 463 + + GH ++ V F+ P ++S S +++ E Sbjct: 320 LYKLPGHA--GSINEVAFH-PDEPIIISASSDKRLYMGE 355 Score = 50.1 bits (118), Expect = 6e-06 Identities = 63/313 (20%), Positives = 126/313 (40%), Gaps = 28/313 (8%) Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248 L GH G V F+ G+ LAS D +++W+ GH V + + N+ Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHY--NT 119 Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308 S L + D V V + + K K + + P CT +D V Sbjct: 120 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCT---GSDDGTV 176 Query: 309 FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE 368 D+R K + + + + N + Q GG D ++++D R +N+ Sbjct: 177 KLWDIR------KKAAIQTFQNTYQVLAVTFND-TSDQIISGGIDNDIKVWDLR---QNK 226 Query: 369 NNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFN-SSHSDGAQYVKR 427 ++ ++T L S +G+ LL++ D + +++ + + VK Sbjct: 227 LTYTMRGHAD----------SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 276 Query: 428 YKGHRNNATVKGVN-FYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486 ++G+ +N + + P + +GS +++W+ +S +I+ + G G +N + Sbjct: 277 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAF 335 Query: 487 HPHLPVLATSGLD 499 HP P++ ++ D Sbjct: 336 HPDEPIIISASSD 348 Score = 39.7 bits (91), Expect = 0.008 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 7/113 (6%) Query: 393 LVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVS 452 L Y+ DG+ L ++ D+ + +++S + + VKR KGH + GP + V + Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDS---ETGERVKRLKGHTSFVNSCYPARRGP--QLVCT 169 Query: 453 GSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505 GSD G + LW+ IQ + V + + + + G+D+D+K+W Sbjct: 170 GSDDGTVKLWDIRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVW 220 Score = 35.0 bits (79), Expect = 0.20 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%) Query: 184 RLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWD---WVRRQPVLDFESGHKSNVF 240 +L + + GH V L + G++L S + D V VWD + ++ + G+ N F Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHN-F 284 Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300 + L S + A R + T + ++ H G+ +++A PD P + Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEP-III 343 Query: 301 SAGED 305 SA D Sbjct: 344 SASSD 348 >gi|8922301 WD repeat domain 70 [Homo sapiens] Length = 654 Score = 50.8 bits (120), Expect = 3e-06 Identities = 109/593 (18%), Positives = 207/593 (34%), Gaps = 108/593 (18%) Query: 18 SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKD 77 ++ S + + E+ E + E+ + + T R ++S DT SS ++ Sbjct: 50 AVERSRKTLEAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQS 109 Query: 78 SDSMEDT------------GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125 SDS +D + +E+ + EEEEE EEE+ + ++ Sbjct: 110 SDSSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHK 169 Query: 126 DQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRL 185 DS + L Sbjct: 170 IPDSHE---------------------------------------------------ITL 178 Query: 186 QHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLD-FESGHKSNVFQAKF 244 +HG T V+ L + G L +G D V WD+ F S Q K Sbjct: 179 KHG----TKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234 Query: 245 LP--NSGDSTLAMCARDGQVRVAE---LSATQCCKNTKRVAQ------HKGASHKLALEP 293 L N+GD L + Q +V + +C K + + H H + P Sbjct: 235 LQYSNTGDMILVVSG-SSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHP 293 Query: 294 DSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRD 353 F++ DA V T ++ + + + + K + T + + A ++ Sbjct: 294 KIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353 Query: 354 QFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYL 413 ++I+D+ N V KF H+ +S + +C+ +S+DG L + D+ + L Sbjct: 354 GSIQIWDR-------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKL 404 Query: 414 FNSSHSDGAQYVKRYKGHRNNATVKGVN--FYGPKSEFVVSGSD------CGHIFLWEKS 465 + D Q+ K T+ + + P + +V+G+ G + +E+ Sbjct: 405 W-----DIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459 Query: 466 SCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLK-DVIKK 524 + Q + ++ VV CL HP L + + K++ + + G K V+K Sbjct: 460 TFQRVYEIDITDASVVRCLW-HPKLNQIMVGTGNGLAKVY---YDPNKSQRGAKLCVVKT 515 Query: 525 NKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESP 577 ++ + ++L Q + H L + RQR ++ + + + E P Sbjct: 516 QRKAKQAETLTQDYIITPHAL-PMFREPRQRSTRKQLEKDRLDPLKSHKPEPP 567 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 15 ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73 A+ S SS EE++ E G + +G S + D+ G N T E G + + Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212 Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132 E+ + D+ ED +E + EEEEEEEEEEE EQ R +K D D+ + Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81 E G E R S + +++ G D G + + T+ E G ++D + Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212 Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135 E+ + DE D EEEEEEEEEEEEE+ Q +R +++ + D R+ Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Score = 39.3 bits (90), Expect = 0.010 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%) Query: 59 RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110 R S S+ + E + E+ SD S ++ G+ + N+E V + EE+EE EE+ EE Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221 Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143 +E+ + + +++ ++E E++ E Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 50.4 bits (119), Expect = 5e-06 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 15 ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73 A+ S SS EE++ E G + +G S + D+ G N T E G + + Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212 Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132 E+ + D+ ED +E + EEEEEEEEEEE EQ R +K D D+ + Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269 Score = 50.1 bits (118), Expect = 6e-06 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81 E G E R S + +++ G D G + + T+ E G ++D + Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212 Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135 E+ + DE D EEEEEEEEEEEEE+ Q +R +++ + D R+ Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Score = 39.3 bits (90), Expect = 0.010 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%) Query: 59 RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110 R S S+ + E + E+ SD S ++ G+ + N+E V + EE+EE EE+ EE Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221 Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143 +E+ + + +++ ++E E++ E Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254 >gi|5803221 WD repeat-containing protein 3 [Homo sapiens] Length = 943 Score = 48.5 bits (114), Expect = 2e-05 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250 GH + TL ++Q G LASGS D ++VWD + + + GHK + QA FL Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLK-GHKDAITQALFLREK-- 161 Query: 251 STLAMCARDGQVRVAELSATQCCK 274 + L +D V+ +L C K Sbjct: 162 NLLVTSGKDTMVKWWDLDTQHCFK 185 Score = 40.4 bits (93), Expect = 0.005 Identities = 68/325 (20%), Positives = 131/325 (40%), Gaps = 35/325 (10%) Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250 GH V TL F+ + S + D + +W+ Q + + F F+P GD Sbjct: 413 GHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSF---FVP--GD 466 Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV-- 308 + + + G++++ +L++ + + H GA ++L PD F++ G D V Sbjct: 467 RQVVIGTKTGKLQLYDLASGNLLET---IDAHDGALWSMSLSPDQR-GFVTGGADKSVKF 522 Query: 309 --FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPA-NTHQFAVGGRDQFVRIYDQRKID 365 F + ++ +L V + + ++ + V+ + N AV D V+I+ +D Sbjct: 523 WDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIF---YVD 579 Query: 366 ENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYV 425 LK F + K + C+ SHDG + D ++ ++ D + + Sbjct: 580 ------TLKFFLSLY----GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSL 629 Query: 426 KRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLE 485 ++ +V + F PKS + I W+ + IQ +EG + CL Sbjct: 630 -----FAHDDSVMYLQFV-PKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIW-CLA 682 Query: 486 PHPHLPVLATSGLDHDVKIWAPTAE 510 P + +S D +++W T E Sbjct: 683 VSPSGDYVVSSSHDKSLRLWERTRE 707 Score = 40.0 bits (92), Expect = 0.006 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 7/119 (5%) Query: 387 KANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPK 446 K +TCL S DG L Y D I +F+ +G + GH+ T + G + Sbjct: 65 KQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGN---VTFNGHKAAITTLKYDQLGGR 121 Query: 447 SEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505 + SGS I +W+ + + ++G K + L +L TSG D VK W Sbjct: 122 ---LASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLR-EKNLLVTSGKDTMVKWW 176 Score = 30.4 bits (67), Expect = 4.8 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 440 VNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLD 499 V G K +V + C H+F+W+ + I ++G K V CL P P LA D Sbjct: 29 VTLRGEKGRYVAVPA-CEHVFIWDLRKGEKILILQGLK-QEVTCLCPSPDGLHLAVGYED 86 Query: 500 HDVKIWA-PTAEASTELTGLKDVIKKNKRER 529 ++I++ + E + G K I K ++ Sbjct: 87 GSIRIFSLLSGEGNVTFNGHKAAITTLKYDQ 117 Score = 30.0 bits (66), Expect = 6.3 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232 C ++F V + L GH V + + G +A+GS D V +W LDF Sbjct: 571 CTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWG-------LDFG 623 Query: 233 SGHKS------NVFQAKFLPNS 248 HKS +V +F+P S Sbjct: 624 DCHKSLFAHDDSVMYLQFVPKS 645 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 4/144 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS + S + E ++S + ++SD S S + + S Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN----SSDS 726 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ S DS D+ + S + ++ S + + + + Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSS 810 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/140 (20%), Positives = 62/140 (44%), Gaps = 5/140 (3%) Query: 6 SSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESR 65 S++D +NG+ ++ ++ ++ G+ S + ++SD S S D + +S + Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576 Query: 66 GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125 +D++SS D S D+ +D + D S+ + + + + + ++ Sbjct: 577 SSDSDSSDSDSSDSSDSDS-----SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631 Query: 126 DQDSSDDERALEDWVSSETS 145 D SD + D SS++S Sbjct: 632 DSSDSDSKSDSSDSNSSDSS 651 Score = 46.2 bits (108), Expect = 9e-05 Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 1/144 (0%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + + ++ + S +SD S S DG + +S Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +++ S + DS + D+ S ++E+ S + + + + Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 +N DSS+ + ++ SS++S Sbjct: 917 SSN-SSDSSESSNSSDNSNSSDSS 939 Score = 45.8 bits (107), Expect = 1e-04 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 2/146 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D +N S SS + S + + +S S E+SD S S D + Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167 Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S++S +D+ +S + DS D+ S + ++ S + + + + Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227 Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145 +N DSSD + + SS++S Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSS 1253 Score = 45.4 bits (106), Expect = 1e-04 Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S++ +D ++ S SSS + S + + ++S S E+SD S S + D + Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS-SDSDSSDSSD 717 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S+ S +D++SS SDS + +D + D S+ + + + Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 +N DS+D + + SS +S Sbjct: 778 DSSN-SSDSNDSSNSSDSSDSSNSS 801 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D +N S SS+ + S + + ++S S ++SD S S D + Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S++S +D+ S + +S D+ + S + ++ S + + + + Sbjct: 1069 SSDS--SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SSE+S Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESS 1151 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 6/149 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 S S+D + +N S S S S + + ++ S +SD S S D + S Sbjct: 561 SDSSDSSDSDSSDSNSS-SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE-----EEEEEEEEEEEEQPRR 116 ++S+ ++S + DSDS D+ + +D + D S+ + + + Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679 Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + E SS++S Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSS 708 Score = 45.1 bits (105), Expect = 2e-04 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 5/149 (3%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S ++ ++ ++ S SS+ + S + + ++S + ++S+ S S D + S Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYS----INDENRVHDRSEEEEEEEEEEEEEQPRRR 117 ++S + S G D DS + D+ + S +D + D S+ + E + Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898 Query: 118 VQRKRANRDQ-DSSDDERALEDWVSSETS 145 + D +SSD + SSE+S Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESS 927 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/144 (21%), Positives = 57/144 (39%), Gaps = 2/144 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S +D +N S SS + S + + +S +SD S S + D + +S Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN--SSDSSDSNSSDSSDSSNSS 983 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ S + DS + D+ S + ++ S + + Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSS 1067 Score = 44.3 bits (103), Expect = 3e-04 Identities = 33/144 (22%), Positives = 62/144 (43%), Gaps = 2/144 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS+ + S + + S ++SD S S D + S Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 ++S + ++SS SDS + + +D + D S+ + + + + Sbjct: 1004 SDSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSS 1061 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SSE+S Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESS 1085 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 9/130 (6%) Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62 S S + +D ++ S SS + S + + + SS E ++SD D + +S Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652 Query: 63 ESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ +S DS DS + + S +D + D S+ + E + Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD------ 706 Query: 122 RANRDQDSSD 131 + D DSSD Sbjct: 707 --SSDSDSSD 714 Score = 43.5 bits (101), Expect = 6e-04 Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 14/145 (9%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS + S + + ++S+ + +SD S S D + + Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S S +D+ S DS D+ S +D + D S + + + Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD----------- 872 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + E SS++S Sbjct: 873 --SSNSSDSSDSSDSNESSNSSDSS 895 Score = 43.1 bits (100), Expect = 7e-04 Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 6/148 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57 SS S + +D +N S SS + S + + ++S S ++SD S S D Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101 Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 + S++S +D+ S + DS + D+ S + ++ S + + E + Sbjct: 1102 SSDSSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159 Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + SS++S Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187 Score = 43.1 bits (100), Expect = 7e-04 Identities = 32/141 (22%), Positives = 57/141 (40%), Gaps = 6/141 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57 SS S + +D +N S SS E S + + ++S S ++SD S S D Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185 Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 + S++S +D+ S + DS D+ S + ++ S + + E + Sbjct: 1186 SSDSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243 Query: 118 VQRKRANRDQDSSDDERALED 138 ++ DSSD + D Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSD 1264 Score = 43.1 bits (100), Expect = 7e-04 Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 7/140 (5%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS + S + + ++S + +SD S S D + S Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDS 1222 Query: 62 TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 ++S +D+ S E D SDS + + + +D + D S+ + +E + + Sbjct: 1223 SDS--SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280 Query: 121 KRANRDQDS--SDDERALED 138 ++ D DS SD + D Sbjct: 1281 NGSDSDSDSEGSDSNHSTSD 1300 Score = 42.7 bits (99), Expect = 0.001 Identities = 29/144 (20%), Positives = 59/144 (40%), Gaps = 1/144 (0%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 S KG S +D ++ S SS + S ++ SS + ++SD S + D + ++ Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS-DSDSSDSDSSDSSDSDSSDSSN 600 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 + ++SS SDS + S ++ + S+ + + + Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSS 684 Score = 42.7 bits (99), Expect = 0.001 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 4/146 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + S + +G ++ S ++S+ S S D + S Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 ++S ++ ESS SDS + S +D + D S+ + E Sbjct: 880 SDSSDSN-ESSNSSDSSDSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937 Query: 122 RANR--DQDSSDDERALEDWVSSETS 145 +N DSSD + + SS++S Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSS 963 Score = 42.7 bits (99), Expect = 0.001 Identities = 32/144 (22%), Positives = 63/144 (43%), Gaps = 8/144 (5%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS +S+D +D +N S SS + S + + ++S+ +SD S S D + +S Sbjct: 968 SSDSNSSDS-SDSSNSSDSSDSSDSSDSSDSSDSSN-----SSDSSDS--SDSSDSSNSS 1019 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ +S + DS D+ S + ++ S + + + + Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSS 1103 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/145 (21%), Positives = 61/145 (42%), Gaps = 6/145 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS+ + S + + ++S ++SD S S D + S Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS-----DSSDSSDSSDSSDSSDSSNS 1057 Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 ++S +D+ S + DS D+ S + ++ S + + + + Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS +S Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSS 1142 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 12/148 (8%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS + S ++ + S ++SD S S D + Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850 Query: 62 TES----RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 ++S R + SS SDS + +D N + S+ + + + Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD--- 907 Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS +S Sbjct: 908 -----SSNSSDSSDSSNSSDSSESSNSS 930 Score = 42.4 bits (98), Expect = 0.001 Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 2/146 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS + S + E ++S S ++SD S S D + Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113 Query: 61 STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S++S + S S + DS D+ + S + ++ S + + + + Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173 Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSS 1199 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS+ + S + + ++S S ++SD S S D + Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S++S +D+ S + DS + D+ S + ++ S + + + + Sbjct: 1162 SSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSS 1244 Score = 42.4 bits (98), Expect = 0.001 Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 4/144 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS+ + S + E ++S + +SD S S D + +S Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD--SSDSSDS--SDSSDSSDSS 1175 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ S + DS D+ S + ++ S + + + + + Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSS 1259 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%) Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62 S S +D ++D ++ + S S + ++ ++S ++SD S S + D + S+ Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690 Query: 63 ESRGTD--TESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 +S + +ESS SDS S N + D S + + + Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS-DS 749 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSS 774 Score = 42.0 bits (97), Expect = 0.002 Identities = 27/136 (19%), Positives = 54/136 (39%), Gaps = 6/136 (4%) Query: 2 SSKGSSTDGRTDLANGS------LSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDG 55 SS S + +D ++GS S S ++ ++S ++SD + S D Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894 Query: 56 GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115 + S++S +D+ +S + DS + D+ S + +N S + + + Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954 Query: 116 RRVQRKRANRDQDSSD 131 ++ DSSD Sbjct: 955 DSSNSSDSSNSSDSSD 970 Score = 42.0 bits (97), Expect = 0.002 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 2/147 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS + S + + ++S S ++SD S S D + Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212 Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S++S +D+ S + DS+ D+ S + ++ S + + + + Q Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272 Query: 120 RKRANRDQDSSDDERALEDWVSSETSA 146 K N + + SD + E S+ +++ Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDSNHSTS 1299 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 14/144 (9%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS+ + S + + +S +SD S S D + +S Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN--SSDSSNSSDSSDSNSSDSS 977 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ S + DS D+ + S D + D S+ + + Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSS--DSSDSSDSSDSSNSSDSSNSSD--------- 1026 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1027 -SSNSSDSSDSSDSSDSSDSSDSS 1049 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + S + + ++S + +SD S S D + S Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDS 1087 Query: 62 TE-SRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 ++ S +D+ S + DS D+ S + ++ S + + + + Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSS 1172 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 4/144 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + S + + ++S + +SD S S D + S Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSNS 1123 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 ++S +D+ S + DS + D+ S + ++ S + + + + Sbjct: 1124 SDS--SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSS 1205 Score = 41.2 bits (95), Expect = 0.003 Identities = 31/144 (21%), Positives = 61/144 (42%), Gaps = 7/144 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS + S + + ++S ++SD S S D + S Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS-----DSSDSSDSSNSSDSSDSSDS 1132 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 ++S +D+ +S + DS D+ S + ++ S + + + Sbjct: 1133 SDS--SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSS 1214 Score = 41.2 bits (95), Expect = 0.003 Identities = 30/145 (20%), Positives = 62/145 (42%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + S + + ++S + +SD S S D + S Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDSSDSSESSDS 1153 Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 ++S +D+ S + DS D+ + S + ++ S + + + + Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSS 1238 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/146 (21%), Positives = 61/146 (41%), Gaps = 4/146 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D +N S SS + S + + ++S + S S S + D + +S Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSS 795 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ +S + DS D+ + +D + D S+ + + + Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS-DSD 854 Query: 122 RANRDQD--SSDDERALEDWVSSETS 145 +NR SSD + + SS++S Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSS 880 Score = 40.8 bits (94), Expect = 0.004 Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D +N S SS + S + + +S S +SD S S D + Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S++S + S DS + D+ +D + D S+ + + + + R Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDS-----SDSSNSSDSSDSSDSSDGSDSDSS--NRSDS 861 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS+++ Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSN 886 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/144 (18%), Positives = 55/144 (38%), Gaps = 2/144 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 S+ S+D + S S + ++ + S ++SD S S D + +S Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS--SDSSNSSDSS 1028 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +D+ S + DS D+ S + ++ S + + + + Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSS 1112 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S++ +D ++ S SS + S + + +S S ++SD S S D + Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083 Query: 61 STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S++S + S S + DS D+ S + ++ S + + + + Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSS 1169 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60 SS S + +D +N S SS + S + ++S+ + +SD S S D + Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S++S +D+ +S + DS D+ S + ++ S + + + Sbjct: 1048 SSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + SS++S Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSS 1130 Score = 40.4 bits (93), Expect = 0.005 Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS+ + S + + ++S + +SD S S D + S Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSDSSDSSNS 1093 Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 ++S +D+ S + DS D+ S + ++ S + + + Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSS 1178 Score = 40.4 bits (93), Expect = 0.005 Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 3/145 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS E S + + +S S ++SD S S D + + Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS--SDSSDSSDS 1117 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S S +D+ S + DS ++ S + E+ S + + + + Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSS 1202 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS + S + + +S S ++SD S S D + Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149 Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S++S +D+ S + DS D+ S + ++ S + + + + Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209 Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + S+E+S Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESS 1235 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 9/153 (5%) Query: 2 SSKGSSTD--GRTDLANGSLSSSPEEMSGAEEGRETS-------SGIEVEASDLSLSLTG 52 SS S+D +D ++ S SS E S + + +S S ++S+ S S Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959 Query: 53 DDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEE 112 D + S++S +D+ S DS D+ S + ++ S + + + Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019 Query: 113 QPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Score = 39.7 bits (91), Expect = 0.008 Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 9/145 (6%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S +D +N S SS + S + + +S S ++SD S S + + Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S++S +D+ S SDS + + +D + D S+ + + + Sbjct: 707 SSDSDSSDSSDSSNSNSSDS-DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS------- 758 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS +S Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSS 783 Score = 38.9 bits (89), Expect = 0.014 Identities = 33/158 (20%), Positives = 65/158 (41%), Gaps = 15/158 (9%) Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSL----------T 51 S S++ +D +N S SS + S + + ++S S ++SD S S + Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785 Query: 52 GDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE----EEEEEEE 107 D + +S S +D+ +S + DS D+ + +D + D S+ + + Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845 Query: 108 EEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145 + + R ++ DSSD + SS++S Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883 Score = 38.9 bits (89), Expect = 0.014 Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 6/145 (4%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60 SS S++ +D ++ S SS + S + + ++S+ + ++SD S S + + Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 S+ES + ++SS SDS + + +D + D S+ + + + + Sbjct: 1147 SSESSDS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DS 1201 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSS 1226 Score = 38.9 bits (89), Expect = 0.014 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 3/132 (2%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + +D ++ S SS + S + + ++S+ + +SD S S D + S Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDS 1201 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 ++S + ++SS SDS + + +D N D S+ + + + Sbjct: 1202 SDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260 Query: 122 RANRDQDSSDDE 133 + D SD + Sbjct: 1261 STSDSNDESDSQ 1272 Score = 38.5 bits (88), Expect = 0.018 Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 10/144 (6%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S++ D +N S SS S + ++S ++SD S S + + + +S Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS-----DSSDSSDSDSSNSSDSSNSS 830 Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121 S +++ S + DS D+ + +D + D S+ + + + Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS----DSN 886 Query: 122 RANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + D SS++S Sbjct: 887 ESSNSSDSSDSSNS-SDSDSSDSS 909 Score = 38.1 bits (87), Expect = 0.023 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 1/92 (1%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS E S + + ++S S ++SD S S + + Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDE 92 ++S+ + ++G D DSDS ++S +D+ Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 37.4 bits (85), Expect = 0.040 Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 8/145 (5%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S + ++ ++ S SS E S + + ++S+ + ++SD S S D + S Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923 Query: 62 TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120 +ES +S ++ + SDS + +D + D S + + + Sbjct: 924 SES-----SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS--NSSDS 976 Query: 121 KRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSS 1001 Score = 37.0 bits (84), Expect = 0.052 Identities = 30/149 (20%), Positives = 61/149 (40%), Gaps = 9/149 (6%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61 SS S +D + + +SS + S + + ++S+ + +SD S S D + S Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDS 761 Query: 62 TESRGT-----DTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRR 116 + S + ++SS SDS + + +D + D S + + + + Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821 Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145 ++ DSSD + + SS++S Sbjct: 822 --NSSDSSNSSDSSDSSNSSDSSDSSDSS 848 Score = 36.6 bits (83), Expect = 0.067 Identities = 31/157 (19%), Positives = 58/157 (36%), Gaps = 12/157 (7%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEG----------RETSSGIEVEASDLSLSLT 51 SS S + +D +N S SS + S ++ ++ S ++SD S S Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742 Query: 52 GDDGGPNRTSTESRGTDTESSGED--KDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEE 109 D + S++S + S+ D SDS + + + +D N + S+ + + Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802 Query: 110 EEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSA 146 ++ D +S D D S S+ Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839 Score = 35.8 bits (81), Expect = 0.11 Identities = 24/110 (21%), Positives = 49/110 (44%), Gaps = 1/110 (0%) Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60 SS S + +D ++ S SS + S + + ++S + E+SD S S D + Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251 Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEE 110 S++S + +S + +SDS +G+ + N + D + ++ Sbjct: 1252 SSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 35.4 bits (80), Expect = 0.15 Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 10/154 (6%) Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLS-LSLTGDDGGPNRT 60 S S++ +D +N S SS + S + + ++S+ + ++SD S S + D + + Sbjct: 968 SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027 Query: 61 STESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119 S S +D+ S + DS DS + + + +D + D S+ + + + + Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087 Query: 120 RKRANR-------DQDSSDDERALEDWVSSETSA 146 +N D S D D S S+ Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121 Score = 35.0 bits (79), Expect = 0.20 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 9/151 (5%) Query: 5 GSSTDGRTDLANG--SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62 G S G ++G S + M G + S +A+ S + + G + S Sbjct: 437 GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496 Query: 63 ESR--GTDTESSG-EDKDSDSMEDTGHYSI----NDENRVHDRSEEEEEEEEEEEEEQPR 115 ES+ G ++S G ED DSDS DT + N+ N +D+S+ + + + + + Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556 Query: 116 RRVQRKRANRDQDSSDDERALEDWVSSETSA 146 ++ S D + D SS++ + Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587 Score = 33.5 bits (75), Expect = 0.57 Identities = 31/148 (20%), Positives = 62/148 (41%), Gaps = 26/148 (17%) Query: 2 SSKGSST---DGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPN 58 SS+G ++ D D NGS + GAE+ S+ + ++ + G++G + Sbjct: 486 SSRGDASYNSDESKDNGNGS------DSKGAEDDDSDSTS---DTNNSDSNGNGNNGNDD 536 Query: 59 RTSTES-RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 ++S +G S + DS + D+ S +D + + S+ + + + + Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS----- 591 Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145 D DSSD + + SS++S Sbjct: 592 --------DSDSSDSSNSSDSSDSSDSS 611 Score = 31.2 bits (69), Expect = 2.8 Identities = 23/146 (15%), Positives = 57/146 (39%), Gaps = 18/146 (12%) Query: 1 MSSKGSSTDGRTDLAN------GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDD 54 ++ +STD ++ G+ S +++ G + + D L D Sbjct: 186 VAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLD--NSD 243 Query: 55 GGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEE----------E 104 G P+ + + ED+++ + +D+ + S E + H + ++ + E Sbjct: 244 GSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKE 303 Query: 105 EEEEEEEEQPRRRVQRKRANRDQDSS 130 + E +E P V + ++ +++S Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENS 329 Score = 29.6 bits (65), Expect = 8.2 Identities = 28/146 (19%), Positives = 56/146 (38%), Gaps = 19/146 (13%) Query: 17 GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDK 76 G +S +E +G ++ S D S + D+ N ++S+G + + S Sbjct: 462 GDDPNSSDESNGNDDANSESDNNSSSRGDASYN--SDESKDNGNGSDSKGAEDDDSDSTS 519 Query: 77 DSDSMEDTGHYSI-NDENRVHDR--------------SEEEEEEEEEEEEEQPRRRVQRK 121 D+++ + G+ + ND+N D S + + + + Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579 Query: 122 RANRDQDSSD--DERALEDWVSSETS 145 + D DSSD D + + SS++S Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSS 605 >gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa [Homo sapiens] Length = 517 Score = 47.8 bits (112), Expect = 3e-05 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 11/173 (6%) Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60 MSS S G G + + ++ A+ GR+ + + SD DDG Sbjct: 216 MSSDASDASGEE---GGRVPKAKKKAPLAKGGRKKK---KKKGSDDEAFEDSDDGDFEGQ 269 Query: 61 STESRGTDTESSGEDKDSDS---MEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 + + SS E+ +S + ++ G +++++ + SEEE+ EE++EEE+ ++ Sbjct: 270 EVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKA 329 Query: 118 VQRKRANRDQDSSDDERALE--DWVSSETSALPRPRWQALPALRERELGSSAR 168 + R +DSS++ + E D S +SAL + + P + G S+R Sbjct: 330 PTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSR 382 Score = 34.7 bits (78), Expect = 0.26 Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 3/97 (3%) Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117 N T T T E++ + H+SI + R+ D+ ++E +EEE+E++ RR+ Sbjct: 145 NFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDE---DEEEKEKRGRRK 201 Query: 118 VQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQA 154 R + +D + D E +P+ + +A Sbjct: 202 ASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKA 238 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 47.0 bits (110), Expect = 5e-05 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 16/110 (14%) Query: 22 SPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSM 81 S E+ G +E E G + E D D+ G E D + G++ D + Sbjct: 158 SDAEVDGVDEEEEDEEGEDEEDED-------DEDGEEEEFDEEDDEDEDVEGDEDDDEVS 210 Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSD 131 E+ + ++ EE+E+E+E+EEEE+ + +RKR D+ D Sbjct: 211 EEEEEFGLD---------EEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251 Score = 37.4 bits (85), Expect = 0.040 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%) Query: 56 GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115 G +R E+ +D E G D++ + E +DE+ + +EE++E+E+ E ++ Sbjct: 147 GYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD 206 Query: 116 RRVQRKRA-----NRDQDSSDDERALE 137 V + D+D +DE E Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEE 233 Score = 30.8 bits (68), Expect = 3.7 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 6/73 (8%) Query: 66 GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125 G D E E DSD+ D DE + E+EE+E++E+ EE+ + + Sbjct: 147 GYDREDQ-EAPDSDAEVDGV-----DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200 Query: 126 DQDSSDDERALED 138 + D DDE + E+ Sbjct: 201 EGDEDDDEVSEEE 213 >gi|5902034 periodic tryptophan protein 1 [Homo sapiens] Length = 501 Score = 47.0 bits (110), Expect = 5e-05 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 6/130 (4%) Query: 190 EGHTGCVNTLHFNQR-GTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248 EGHT V L +N+ LAS S D V++WD +P + H V +F P Sbjct: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311 Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308 TL + D V + + + + R+ + G ++ SPC FL++ +D V Sbjct: 312 AQ-TLISGSYDKSVALYDCRSPD---ESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFV 367 Query: 309 FTIDLRQDRP 318 + +D R D+P Sbjct: 368 YNLDARSDKP 377 Score = 35.8 bits (81), Expect = 0.11 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 42/216 (19%) Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360 SA D V D+ +PA+ L V +K + T+ +P G D+ V +YD Sbjct: 274 SASADNTVILWDMSLGKPAASLAVHTDK-----VQTLQFHPFEAQTLISGSYDKSVALYD 328 Query: 361 QRKIDENEN----NGVLKK-----FCPHHLVNSESKANITCLVYSHDGTELLASYNDEDI 411 R DE+ +G +++ F P H + S VY+ D + +D+ I Sbjct: 329 CRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG----FVYNLD------ARSDKPI 378 Query: 412 YLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQ 471 + N+ +N + G++ +V+ S ++ +W+ + Sbjct: 379 FTLNA----------------HNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSL 422 Query: 472 FMEGD-KGGVVNCLEPHPHLP-VLATSGLDHDVKIW 505 D K GV+ C P LP + A G +++W Sbjct: 423 VHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVW 458 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 46.6 bits (109), Expect = 7e-05 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 13/104 (12%) Query: 41 VEASDLSLSL--TGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDR 98 VE SD++ G GGPN T T T +S GE+++ + E+ +E Sbjct: 375 VEPSDIAACFREAGFGGGPNATIT----TSLKSEGEEEEEEEEEE-------EEEEGEGE 423 Query: 99 SEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSS 142 EEEE EEEEEE + + + + D DE ED SS Sbjct: 424 EEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467 Score = 34.7 bits (78), Expect = 0.26 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 15/101 (14%) Query: 17 GSLSSSPEEMSGAEEGRETSS-GIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE--SSG 73 G + S EE EE E+SS G+E E + G G E++ G Sbjct: 452 GDVDSDEEE----EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507 Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQP 114 ED DSDS E+ ++ D +E+++++EE+ +E P Sbjct: 508 EDSDSDSEEE--------DDEEEDDEDEDDDDDEEDGDEVP 540 >gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] Length = 1495 Score = 46.6 bits (109), Expect = 7e-05 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 21/136 (15%) Query: 54 DGGPNRTSTESRGTDTESSGEDKDSDSMEDT-------GHYSINDENRVHDR---SEEEE 103 +G N T+ E G T + D D +S E T H++ + + + + EEEE Sbjct: 790 EGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEMIPSDEEEE 849 Query: 104 EEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALREREL 163 ++EEEEEEE+PR + +R + D +++DE S + AL + EL Sbjct: 850 DDEEEEEEEEPRLTI-NQREDEDGMANEDELDNTYTGSGDEDALSE---------EDDEL 899 Query: 164 GSSARFV-YEACGARV 178 G +A++ + CG V Sbjct: 900 GEAAKYEDVKECGKHV 915 >gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] Length = 589 Score = 46.6 bits (109), Expect = 7e-05 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%) Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250 GH G V +L F+ G +LAS +D ++ +WD + GH N+ F P+SG Sbjct: 466 GHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELR-GHTDNITSLTFSPDSG- 523 Query: 251 STLAMCARDGQVRVAELSATQC 272 +A + D VRV ++ T C Sbjct: 524 -LIASASMDNSVRVWDIRNTYC 544 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 13/173 (7%) Query: 190 EGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSG 249 +GH V L + + ASGS D +W + R P L +GH ++V KF PNS Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP-LRIYAGHLADVDCVKFHPNS- 438 Query: 250 DSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVF 309 + LA + D VR L + Q + + H+G LA P+ SAGED + Sbjct: 439 -NYLATGSTDKTVR---LWSAQQGNSVRLFTGHRGPVLSLAFSPNGK-YLASAGEDQRLK 493 Query: 310 TIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQR 362 DL + KE T ++ A D VR++D R Sbjct: 494 LWDLASG------TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540 Score = 39.7 bits (91), Expect = 0.008 Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 9/157 (5%) Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250 GH V+ + F+ +LA+GS D V +W + V F +GH+ V F PN Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF-TGHRGPVLSLAFSPNG-- 480 Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFT 310 LA D ++++ +L++ K + H L PDS SA D V Sbjct: 481 KYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSG-LIASASMDNSVRV 536 Query: 311 IDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQF 347 D+R ++ + VG+YT ++ + QF Sbjct: 537 WDIRNTYCSAP--ADGSSSELVGVYTGQMSNVLSVQF 571 Score = 37.4 bits (85), Expect = 0.040 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 18/152 (11%) Query: 396 SHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSD 455 SHD T L S+ D ++ Y GH A V V F+ P S ++ +GS Sbjct: 403 SHDRTARLWSF-------------DRTYPLRIYAGHL--ADVDCVKFH-PNSNYLATGST 446 Query: 456 CGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW-APTAEASTE 514 + LW ++ G +G V++ L P+ LA++G D +K+W + E Sbjct: 447 DKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 505 Query: 515 LTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546 L G D I D + + +S +W Sbjct: 506 LRGHTDNITSLTFSPDSGLIASASMDNSVRVW 537 Score = 30.4 bits (67), Expect = 4.8 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 1/71 (1%) Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504 P S + SGS LW ++ G V +C++ HP+ LAT D V++ Sbjct: 394 PYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV-DCVKFHPNSNYLATGSTDKTVRL 452 Query: 505 WAPTAEASTEL 515 W+ S L Sbjct: 453 WSAQQGNSVRL 463 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,171,101 Number of Sequences: 37866 Number of extensions: 1254478 Number of successful extensions: 27620 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 636 Number of HSP's successfully gapped in prelim test: 460 Number of HSP's that attempted gapping in prelim test: 11601 Number of HSP's gapped (non-prelim): 8276 length of query: 597 length of database: 18,247,518 effective HSP length: 108 effective length of query: 489 effective length of database: 14,157,990 effective search space: 6923257110 effective search space used: 6923257110 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.