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Search of human proteins with 30089954
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30089954 H326 [Homo sapiens]
(597 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30089954 H326 [Homo sapiens] 1224 0.0
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 845 0.0
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens] 795 0.0
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens] 145 8e-35
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens] 145 8e-35
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 134 3e-31
gi|55741849 WD repeat domain 22 [Homo sapiens] 99 8e-21
gi|16554629 WD repeat domain 5 [Homo sapiens] 74 5e-13
gi|16554627 WD repeat domain 5 [Homo sapiens] 74 5e-13
gi|23199987 WD repeat domain 5B [Homo sapiens] 66 1e-10
gi|147904340 WD repeat domain 82 [Homo sapiens] 62 2e-09
gi|19913369 transducin beta-like 3 [Homo sapiens] 57 5e-08
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 57 6e-08
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 57 6e-08
gi|7706657 cell division cycle 40 homolog [Homo sapiens] 53 7e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 53 9e-07
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 52 1e-06
gi|113865883 WD repeat domain 38 [Homo sapiens] 51 3e-06
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 51 3e-06
gi|8922301 WD repeat domain 70 [Homo sapiens] 51 3e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 50 5e-06
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 50 5e-06
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 49 2e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 48 2e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 48 3e-05
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 47 5e-05
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 47 5e-05
gi|21735415 centromere protein B [Homo sapiens] 47 7e-05
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 47 7e-05
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 47 7e-05
>gi|30089954 H326 [Homo sapiens]
Length = 597
Score = 1224 bits (3166), Expect = 0.0
Identities = 597/597 (100%), Positives = 597/597 (100%)
Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60
MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT
Sbjct: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR
Sbjct: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
Query: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180
KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV
Sbjct: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180
Query: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240
QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF
Sbjct: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240
Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300
QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL
Sbjct: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300
Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD
Sbjct: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
Query: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420
QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD
Sbjct: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420
Query: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480
GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV
Sbjct: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480
Query: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540
VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF
Sbjct: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540
Query: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS
Sbjct: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 845 bits (2183), Expect = 0.0
Identities = 426/632 (67%), Positives = 489/632 (77%), Gaps = 36/632 (5%)
Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD-----DG 55
MS + STDG DL SL SSPEE SGA E SS I++ S+LS+++TGD DG
Sbjct: 1 MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60
Query: 56 G-PNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVH------------------ 96
G PN STE+R +D ES+ ED + +S+ED H+ ++ E+ H
Sbjct: 61 GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
Query: 97 -----------DRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
+ EEEEEEEEEEEEEQPR Q N +Q S ++++ALE+WVSSETS
Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180
Query: 146 ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRG 205
ALPRPRWQ + AL +R+LGS RFVYEACGAR FVQRFRLQ+ L H GCVNT+HFNQRG
Sbjct: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240
Query: 206 TWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVA 265
T LAS DDLKV+VWDWVR++PVL+FESGH +NVFQAKFLPN GDSTLAMCARDGQVRVA
Sbjct: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300
Query: 266 ELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVT 325
EL NTK VAQH+G +HKLALEPDSP FL++GEDAVVFTIDLRQDRPASK+VVT
Sbjct: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360
Query: 326 KEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSE 385
+E +KKVGLYTI VNPANT+QFAVGG+DQFVRIYDQRKID+ ENNGVLKKF PHHLVN +
Sbjct: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420
Query: 386 SKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGP 445
NITC+VYSHDGTELLASYND+DIYLFNSSHSDGAQY KR+KGHRNN TVKGVNFYGP
Sbjct: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480
Query: 446 KSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
+SEFVVSGSDCGHIF WEKSSCQIIQF++G + G +NCLEPHP+LPVLA SGLDHDVKIW
Sbjct: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540
Query: 506 APTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPG 565
PTA+A+TELTGLK VIKKNK ERDEDSLH LFD +MLWFL+ H+ QR H+ WR
Sbjct: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600
Query: 566 VGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
D +SDES S+S+TS EEE DRVQCMPS
Sbjct: 601 AEFPDEESDESSSTSETS-EEEVQDRVQCMPS 631
>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
Length = 600
Score = 795 bits (2052), Expect = 0.0
Identities = 410/604 (67%), Positives = 474/604 (78%), Gaps = 11/604 (1%)
Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD--DGG-P 57
MS + ST G DL SL SSPEE SG SS IE+ A++ S GD DGG
Sbjct: 1 MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60
Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDT--GHYSINDENRVHDRSEEEEEEEEE-EEEEQP 114
N STE++ TD+ESS ED + +SM + G+ + +E +R EEEEE EEE EEEEQP
Sbjct: 61 NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEET---EREEEEEEMEEEGEEEEQP 117
Query: 115 RRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEAC 174
R + N DQ D+++ALE+W+SSETSALPR RWQ L ALR+R+LGSSARFVYEAC
Sbjct: 118 RMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEAC 177
Query: 175 GARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESG 234
GAR FVQRFRLQ+ L H G V+T+HFNQRGT LAS DDL+V+VWDWVR++PVL+FESG
Sbjct: 178 GARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESG 237
Query: 235 HKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPD 294
H NV QAKF PN GDSTLAMC DGQVRVAEL C+NTKRVA+H+G +H+LALEPD
Sbjct: 238 HDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPD 297
Query: 295 SPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQ 354
SP FL++GEDAVVFTIDLRQDRPASK+VVT+E +KKVGLYTI +NPAN +QFAVGG DQ
Sbjct: 298 SPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQ 357
Query: 355 FVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLF 414
FVRIYDQR+ID+ ENNGVLKKF PHHLV + NITC+VYSHDGTELLASYNDEDIYLF
Sbjct: 358 FVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLF 417
Query: 415 NSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFME 474
NSS SDGAQYVKRYKGHRNN T+K VNFYGP+SEFVVSGSDCGH+F WEKSS QIIQFME
Sbjct: 418 NSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFME 477
Query: 475 GDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSL 534
GD+G +VNCLEPHP+LPVLATSGLD V+IW PTA+ +TELTGLKDVIKKNK+ERDED+L
Sbjct: 478 GDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNL 537
Query: 535 HQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADS-DESPSSSDTSDEEEGPDRVQ 593
+ TD FD+ ML F + HL QR H WR+ G D + DES S+SDTS EEEG DRVQ
Sbjct: 538 NYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTS-EEEGQDRVQ 596
Query: 594 CMPS 597
C+PS
Sbjct: 597 CIPS 600
>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
Length = 860
Score = 145 bits (367), Expect = 8e-35
Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%)
Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215
+R+R LG +R G R F+QR +L+ L H GCVNT+ +N G ++ SGSDD
Sbjct: 14 VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73
Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275
K+V+ + R+ + SGH++N+F AKFLP + D + C+ DG + +
Sbjct: 74 KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133
Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330
+ H G ++++ P+ P TFLS GED V D R K TKE K
Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188
Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380
+ ++ + P + AVG D VRIYD+R + G++ +F P H
Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248
Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415
L N + +T L YS DG E+L SY+ + IYLF+
Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 105 bits (262), Expect = 1e-22
Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%)
Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
YKGHRN+ T +K NF+G + FV+SGSDCGHIF+W++ + + + +E D VVNCL+P
Sbjct: 713 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 769
Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
HP P+LA+SG+D+D+KIW+P E+ L D + E++ + + S ML
Sbjct: 770 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 829
Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575
L ++H+R R R G G + + DE
Sbjct: 830 MLASLNHIRADRLEGD-RSEGSGQENENEDE 859
>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
Length = 880
Score = 145 bits (367), Expect = 8e-35
Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%)
Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215
+R+R LG +R G R F+QR +L+ L H GCVNT+ +N G ++ SGSDD
Sbjct: 14 VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73
Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275
K+V+ + R+ + SGH++N+F AKFLP + D + C+ DG + +
Sbjct: 74 KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133
Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330
+ H G ++++ P+ P TFLS GED V D R K TKE K
Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188
Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380
+ ++ + P + AVG D VRIYD+R + G++ +F P H
Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248
Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415
L N + +T L YS DG E+L SY+ + IYLF+
Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281
Score = 105 bits (262), Expect = 1e-22
Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%)
Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
YKGHRN+ T +K NF+G + FV+SGSDCGHIF+W++ + + + +E D VVNCL+P
Sbjct: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789
Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
HP P+LA+SG+D+D+KIW+P E+ L D + E++ + + S ML
Sbjct: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849
Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575
L ++H+R R R G G + + DE
Sbjct: 850 MLASLNHIRADRLEGD-RSEGSGQENENEDE 879
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 134 bits (336), Expect = 3e-31
Identities = 91/309 (29%), Positives = 145/309 (46%), Gaps = 47/309 (15%)
Query: 179 FVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSN 238
F++R L+ L+GH+GCVN L +N++G LASGSDD +VWD + + +L +GH +N
Sbjct: 33 FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92
Query: 239 VFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
+F KFLP++GD L A D +V V +L+ + H ++A P P T
Sbjct: 93 IFSVKFLPHAGDRILITGAADSKVHVHDLTVKE---TIHMFGDHTNRVKRIATAPMWPNT 149
Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVV--TKEKEKKVGLYTIYVNPANTHQFAVGGRDQFV 356
F SA ED ++ DLR++ S++++ T+ + V + VNP + + AVG FV
Sbjct: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209
Query: 357 RIYDQRKIDENEN---------------------NGVLKKFCPHHL------VNSESKAN 389
R+YD R I + +G + + HL N+ +
Sbjct: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269
Query: 390 I-TCLVYSHDGTELLASYNDEDIYLFN--------------SSHSDGAQYVKRYKGHRNN 434
+ T + +S +GTELL + E +YLF+ HS G Q K +N
Sbjct: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329
Query: 435 ATVKGVNFY 443
G++ +
Sbjct: 330 GVSNGLHLH 338
Score = 95.5 bits (236), Expect = 1e-19
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 38/199 (19%)
Query: 405 SYNDEDIYLFNSSHSDGAQYVKRYKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWE 463
S +++++ L S+ Y RY GH N T +K NF+G ++++VSGSD G F+WE
Sbjct: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565
Query: 464 KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTG-----L 518
K + +++ ++GD+ +VNCL+PHP LATSG+D V++W P E S +LTG +
Sbjct: 566 KETTNLVRVLQGDE-SIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDM 623
Query: 519 KDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPS 578
+ + N+R + D L L + + L G GA+D
Sbjct: 624 EGASQANQRRMNADPLEVMLLNMGYRITGL-------------SSGGAGASD-------- 662
Query: 579 SSDTSDEEEGPDRVQCMPS 597
DE+ +VQC PS
Sbjct: 663 -----DEDSSEGQVQCRPS 676
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 99.4 bits (246), Expect = 8e-21
Identities = 84/334 (25%), Positives = 156/334 (46%), Gaps = 35/334 (10%)
Query: 189 LEGHTGCVNTLHF-NQRGTWLASGSDDLKVVVWDWVR----RQPVLDFESGHKSNVFQAK 243
L GH GCVN + F N G WL SG DD +V++W + R + + H SN+F
Sbjct: 49 LLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLA 108
Query: 244 FLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAG 303
F NSG++ + D QV + ++ +++ T V H+ A + L++ P + F S+
Sbjct: 109 F--NSGNTKVFSGGNDEQVILHDVESSE----TLDVFAHEDAVYGLSVSPVNDNIFASSS 162
Query: 304 EDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRK 363
+D V D+R+ + +++ NP A + V ++D RK
Sbjct: 163 DDGRVLIWDIRESPHGEPFCLANYPS---AFHSVMFNPVEPRLLATANSKEGVGLWDIRK 219
Query: 364 IDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQ 423
+ L ++ + + S ++ +GT+LLA L++ HS
Sbjct: 220 PQSS-----LLRYGGNLSLQSAMSVR-----FNSNGTQLLALRRRLPPVLYDI-HSRLPV 268
Query: 424 YVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLW----EKSSCQIIQFMEGD--- 476
+ +G+ N+ T+K F G + ++++SGSD ++++W + + I + + G
Sbjct: 269 FQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMV 328
Query: 477 -KG--GVVNCLEPHPHLPVLATSGLDHDVKIWAP 507
KG +VN + +PH ++ +SG++ +KIW+P
Sbjct: 329 LKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSP 362
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 73.6 bits (179), Expect = 5e-13
Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%)
Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239
+ L+ L GHT V+++ F+ G WLAS S D + +W + FE SGHK +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90
Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
+ S DS L + A D + +++ ++S+ +C K K
Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126
Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347
G VF + P S L+V+ ++ V ++ + + +P + F
Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406
G YD +I + + LK + ++ + +S +G +LA+
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233
Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466
D + L++ S + +K Y GH+N NF +++VSGS+ +++W +
Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290
Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505
+I+Q ++G V++ HP ++A++ L++D +K+W
Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 73.6 bits (179), Expect = 5e-13
Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%)
Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239
+ L+ L GHT V+++ F+ G WLAS S D + +W + FE SGHK +
Sbjct: 35 YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90
Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
+ S DS L + A D + +++ ++S+ +C K K
Sbjct: 91 SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126
Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347
G VF + P S L+V+ ++ V ++ + + +P + F
Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406
G YD +I + + LK + ++ + +S +G +LA+
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233
Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466
D + L++ S + +K Y GH+N NF +++VSGS+ +++W +
Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290
Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505
+I+Q ++G V++ HP ++A++ L++D +K+W
Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 65.9 bits (159), Expect = 1e-10
Identities = 70/328 (21%), Positives = 142/328 (43%), Gaps = 37/328 (11%)
Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFES---GHKSNV 239
+ L+ L GHT V+++ F+ G WLAS S D +++W + +E GH +
Sbjct: 31 YALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK----YEKTLYGHNLEI 86
Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTF 299
+ +S S L + D +++ ++ + +C K K H P S
Sbjct: 87 SDVAW--SSDSSRLVSASDDKTLKLWDVRSGKCLKTLKG---HSNYVFCCNFNPPSNL-I 140
Query: 300 LSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIY 359
+S D V +++ + L + + ++ N + + G D RI+
Sbjct: 141 ISGSFDETVKIWEVKTGKCLKTLSAHSDP-----VSAVHFNCSGS-LIVSGSYDGLCRIW 194
Query: 360 DQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHS 419
D C LV+ ++ ++ + +S +G +L + D + L++ S
Sbjct: 195 DAASGQ-----------CLKTLVDDDNPP-VSFVKFSPNGKYILTATLDNTLKLWDYSRG 242
Query: 420 DGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGG 479
+ +K Y GH+N NF +++VSGS+ +++W + +I+Q ++G
Sbjct: 243 ---RCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299
Query: 480 VVNCLEPHPHLPVLATSGLDHD--VKIW 505
V++ HP ++A++ L++D +K+W
Sbjct: 300 VISA-ACHPTENLIASAALENDKTIKLW 326
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 61.6 bits (148), Expect = 2e-09
Identities = 74/338 (21%), Positives = 131/338 (38%), Gaps = 40/338 (11%)
Query: 180 VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNV 239
++ FR+ ++ +N F+ G + S SDD +V++D +P S K V
Sbjct: 8 LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYS-KKYGV 66
Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPC-- 297
++ + + D +R L + K + G S ++ SP
Sbjct: 67 DLIRYTHAANTVVYSSNKIDDTIRYLSLH------DNKYIRYFPGHSKRVVALSMSPVDD 120
Query: 298 TFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ-----FAVGGR 352
TF+S D + DLR GL + P + FA G
Sbjct: 121 TFISGSLDKTIRLWDLRSPNCQ-------------GLMHLQGKPVCSFDPEGLIFAAGVN 167
Query: 353 DQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIY 412
+ V++YD R D+ G F + + T L +S+DG +L S N I
Sbjct: 168 SEMVKLYDLRSFDK----GPFATFKMQY----DRTCEWTGLKFSNDGKLILISTNGSFIR 219
Query: 413 LFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQF 472
L ++ + + G+ N+ V + P S+F++ GS+ G I +W S +
Sbjct: 220 LIDAFKG---VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAV 276
Query: 473 MEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAE 510
++G G + CL+ +P A++ ++ W PT +
Sbjct: 277 LDGKHTGPITCLQFNPKFMTFASA--CSNMAFWLPTID 312
>gi|19913369 transducin beta-like 3 [Homo sapiens]
Length = 808
Score = 57.0 bits (136), Expect = 5e-08
Identities = 78/321 (24%), Positives = 119/321 (37%), Gaps = 32/321 (9%)
Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251
HT V T+ F+ T LA+G D V VWD VR F G V F P+
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFR-GSPGVVHLVAFHPDPTRL 166
Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311
L A D +RV L C + H A LA D T LS+G D +
Sbjct: 167 LLFSSATDAAIRVWSLQDRSC---LAVLTAHYSAVTSLAFSADGH-TMLSSGRDKICIIW 222
Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ----FAVGGRDQFVRIYDQRKIDEN 367
DL+ + + V + E V L V+ F G +R+++
Sbjct: 223 DLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWE------- 275
Query: 368 ENNGVLKKFCPHHLVNSESKA-NITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVK 426
C + +T +H +L + D ++ L+ + + K
Sbjct: 276 ----AASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEAR---SLRLQK 328
Query: 427 RYKGHRNNATVKGVNFYGPKSEFVV--SGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCL 484
++ G+ + V V F GP+ VV S S C +F + S+CQI+ +V L
Sbjct: 329 QFAGY--SEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH----GHTDIVLAL 382
Query: 485 EPHPHLPVLATSGLDHDVKIW 505
+ + A+ D V+IW
Sbjct: 383 DVFRKGWLFASCAKDQSVRIW 403
Score = 37.0 bits (84), Expect = 0.052
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504
P + + +GS LW CQ++ G + G+ C++ P VLAT+ D +K+
Sbjct: 489 PNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLW-CVQFSPMDQVLATASADGTIKL 547
Query: 505 WA 506
WA
Sbjct: 548 WA 549
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%)
Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253
G V + FN G + + D + +W+ +R +L SGH V A + +S+L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82
Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313
D V + ++++ Q ++ H G + + ++ LS D+ + D
Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138
Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373
R RP V E + G+ ++ V+ H+ G D VR YD R
Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182
Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433
L + + ITC +S DG L S D + L + D + + YKGH+N
Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234
Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493
K + VVS S+ G +F W+ + + GVV L HP P L
Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292
Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517
T+ + V+ W A + + G
Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%)
Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223
G A +++ +V V++FR GH G VNT+ FN+ T + SGS D + WD
Sbjct: 87 GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139
Query: 224 RRQP 227
R+P
Sbjct: 140 SRRP 143
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 56.6 bits (135), Expect = 6e-08
Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%)
Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253
G V + FN G + + D + +W+ +R +L SGH V A + +S+L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82
Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313
D V + ++++ Q ++ H G + + ++ LS D+ + D
Sbjct: 83 CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138
Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373
R RP V E + G+ ++ V+ H+ G D VR YD R
Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182
Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433
L + + ITC +S DG L S D + L + D + + YKGH+N
Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234
Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493
K + VVS S+ G +F W+ + + GVV L HP P L
Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292
Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517
T+ + V+ W A + + G
Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315
Score = 40.4 bits (93), Expect = 0.005
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%)
Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223
G A +++ +V V++FR GH G VNT+ FN+ T + SGS D + WD
Sbjct: 87 GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139
Query: 224 RRQP 227
R+P
Sbjct: 140 SRRP 143
>gi|7706657 cell division cycle 40 homolog [Homo sapiens]
Length = 579
Score = 53.1 bits (126), Expect = 7e-07
Identities = 92/469 (19%), Positives = 179/469 (38%), Gaps = 50/469 (10%)
Query: 41 VEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE 100
VE ++ + LT + G +T + + ++S D + Y DE V SE
Sbjct: 156 VEEAEKNQGLTVFETGQKKTEKRKKFKENDASNID---GFLGPWAKYV--DEKDVAKPSE 210
Query: 101 EEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRE 160
EE++E +E ++ ++ Q + ++ + + + D+ +P+
Sbjct: 211 EEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQ----------- 259
Query: 161 RELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLH-FNQRGTWLASGSDDLKVVV 219
++G + R + ++ + ++ H GHT V+ + F G L S S D K+ +
Sbjct: 260 -DVGVNLRSTMPP--EKCYLPKKQI-HVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKL 315
Query: 220 WDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN-TKR 278
W+ + L GH V F N+ + A D +++ + QC T R
Sbjct: 316 WEVYGERRCLRTFIGHSKAVRDICF--NTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR 373
Query: 279 VAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIY 338
+ K + D F++ D + D+R + +E ++ +G
Sbjct: 374 KVPY---CVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGE------IVQEYDRHLGAVNTI 424
Query: 339 VNPANTHQFAVGGRDQFVRIYD-QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSH 397
V +F D+ +R+++ +D + S ++ + S
Sbjct: 425 VFVDENRRFVSTSDDKSLRVWEWDIPVD-------------FKYIAEPSMHSMPAVTLSP 471
Query: 398 DGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCG 457
+G L D I +F + + K +KGH V+F P +V+SG G
Sbjct: 472 NGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDF-SPDMSYVISGDGNG 530
Query: 458 HIFLWE-KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
+ +W+ K++ +F DK + PH V+ T G D +K+W
Sbjct: 531 KLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVI-TCGWDGLIKLW 578
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 52.8 bits (125), Expect = 9e-07
Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 24/167 (14%)
Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDT 84
E G EG + E+ A D + G++G TES+ E+ GE K+ + +
Sbjct: 801 EGKGDNEGEDEG---EIHAEDGEMK--GNEG-----ETESQELSAENHGEAKNDEKGVED 850
Query: 85 GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSET 144
G S ++ + EEE+EEEEEEEE++ + + +++ ++E DW +
Sbjct: 851 GGGSDGGDSEEEEEEEEEQEEEEEEEEQEE----EEEEEEEEEEKGNEEPLSLDWPETRQ 906
Query: 145 S--------ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRF 183
+ P W +P +R +E S FV+ G+ +++ F
Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQE--SRKFFVFTFLGSIMWIAMF 951
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 52.4 bits (124), Expect = 1e-06
Identities = 83/356 (23%), Positives = 140/356 (39%), Gaps = 37/356 (10%)
Query: 24 EEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE-----SRGTDTESSGEDKDS 78
EE+ EE + A LS + D G NRT GT ES+ ++
Sbjct: 45 EELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNR-- 102
Query: 79 DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALED 138
M H + + S+EEEEEE+EE+EE+ + +++ R
Sbjct: 103 -LMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMV---PHYGGINRVRVS 158
Query: 139 WVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQ----HGLEGHTG 194
W+ E A W + L + V E F++ + Q GH G
Sbjct: 159 WLGEEPVA---GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMG 215
Query: 195 CVNTLHFNQRGTW-LASGSDDLKVVVW------DW-VRRQPVLDFESGHKSNVFQAKFLP 246
L ++ R T L +G + +W W V ++P + GH +V ++ P
Sbjct: 216 EGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFV----GHTRSVEDLQWSP 271
Query: 247 NSGDSTLAMCARDGQVRVAELSA--TQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE 304
++ A C+ D +R+ ++ A ++ C T A H G + ++ P LS G+
Sbjct: 272 TE-NTVFASCSADASIRIWDIRAAPSKACMLTTATA-HDGDVNVISWSRREP-FLLSGGD 328
Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
D + DLRQ + S + K+ V ++ +P ++ FA G D + +D
Sbjct: 329 DGALKIWDLRQFKSGSPVATFKQHVAPV--TSVEWHPQDSGVFAASGADHQITQWD 382
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 446 KSEFVVSGSDCGHIFLWE----KSSCQIIQFMEGDKGGVVNCLEPHPH-LPVLATSGLDH 500
+ F++SG D G + +W+ KS + F + V +E HP V A SG DH
Sbjct: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQ--HVAPVTSVEWHPQDSGVFAASGADH 376
Query: 501 DVKIWAPTAEASTE 514
+ W E E
Sbjct: 377 QITQWDLAVERDPE 390
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 50.8 bits (120), Expect = 3e-06
Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 32/285 (11%)
Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251
H G VN+ F+ G L +GS+D V W+ R +L GH V +F P+
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWE-TRSGQLLWRLGGHTGPVKFCRFSPDGHLF 78
Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311
A C D VR+ +++ +C + K H+ + ++ PDS S G D V
Sbjct: 79 ASASC--DCTVRLWDVARAKCLRVLK---GHQRSVETVSFSPDSR-QLASGGWDKRVMLW 132
Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNG 371
D++ + LV ++ + + A G D V I+D R + ++
Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDF------SPTVNCLATGSWDSTVHIWDLRMVTPAVSHQ 186
Query: 372 VLKKFCPHHLVNSESKANITCLVYSHDGTELLASYN-DEDIYLFNSSHSDGAQYVKRYKG 430
L+ ANI+CL YS G LLAS + D+ I+++ + S + + KG
Sbjct: 187 ALE----------GHSANISCLCYSASG--LLASGSWDKTIHIWKPTTS---SLLIQLKG 231
Query: 431 HRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEG 475
H VK + F P ++ S + +W+ ++ + ++ ++G
Sbjct: 232 H--VTWVKSIAF-SPDELWLASAGYSRMVKVWDCNTGKCLETLKG 273
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
L GHTG V F+ G AS S D V +WD V R L GH+ +V F P+S
Sbjct: 59 LGGHTGPVKFCRFSPDGHLFASASCDCTVRLWD-VARAKCLRVLKGHQRSVETVSFSPDS 117
Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE-DAV 307
LA D +V + ++ + Q + + H+ + P C L+ G D+
Sbjct: 118 --RQLASGGWDKRVMLWDVQSGQM---LRLLVGHRDSIQSSDFSPTVNC--LATGSWDST 170
Query: 308 VFTIDLRQDRPA 319
V DLR PA
Sbjct: 171 VHIWDLRMVTPA 182
Score = 38.9 bits (89), Expect = 0.014
Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232
C R++ V R + L+GH V T+ F+ LASG D +V++WD V+ +L
Sbjct: 85 CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD-VQSGQMLRLL 143
Query: 233 SGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAEL 267
GH+ ++ + F P + LA + D V + +L
Sbjct: 144 VGHRDSIQSSDFSPTV--NCLATGSWDSTVHIWDL 176
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNC- 483
V+R K + + + P + +++GS+ G ++ WE S Q++ + G G V C
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70
Query: 484 LEPHPHLPVLATSGLDHDVKIW 505
P HL A++ D V++W
Sbjct: 71 FSPDGHL--FASASCDCTVRLW 90
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 50.8 bits (120), Expect = 3e-06
Identities = 67/279 (24%), Positives = 118/279 (42%), Gaps = 32/279 (11%)
Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
L+GH+G V LH+N G+ L S S D V VWD + V + GH S V + +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFV-NSCYPARR 162
Query: 249 GDSTLAMCARDGQVRVAEL---SATQCCKNTKRVAQHKGASHKLALE-PDSPCTFLSAGE 304
G + + DG V++ ++ +A Q +NT +V LA+ D+ +S G
Sbjct: 163 GPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV---------LAVTFNDTSDQIISGGI 213
Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKI 364
D + DLRQ++ +T T + D VR++D R
Sbjct: 214 DNDIKVWDLRQNK------LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPF 267
Query: 365 DENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQY 424
E K ++ N E N+ +S DG+++ A D +Y+++++ +
Sbjct: 268 APKER---CVKIFQGNVHNFEK--NLLRCSWSPDGSKIAAGSADRFVYVWDTT---SRRI 319
Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWE 463
+ + GH ++ V F+ P ++S S +++ E
Sbjct: 320 LYKLPGHA--GSINEVAFH-PDEPIIISASSDKRLYMGE 355
Score = 50.1 bits (118), Expect = 6e-06
Identities = 63/313 (20%), Positives = 126/313 (40%), Gaps = 28/313 (8%)
Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
L GH G V F+ G+ LAS D +++W+ GH V + + N+
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHY--NT 119
Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308
S L + D V V + + K K + + P CT +D V
Sbjct: 120 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCT---GSDDGTV 176
Query: 309 FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE 368
D+R K + + + + N + Q GG D ++++D R +N+
Sbjct: 177 KLWDIR------KKAAIQTFQNTYQVLAVTFND-TSDQIISGGIDNDIKVWDLR---QNK 226
Query: 369 NNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFN-SSHSDGAQYVKR 427
++ ++T L S +G+ LL++ D + +++ + + VK
Sbjct: 227 LTYTMRGHAD----------SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 276
Query: 428 YKGHRNNATVKGVN-FYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
++G+ +N + + P + +GS +++W+ +S +I+ + G G +N +
Sbjct: 277 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAF 335
Query: 487 HPHLPVLATSGLD 499
HP P++ ++ D
Sbjct: 336 HPDEPIIISASSD 348
Score = 39.7 bits (91), Expect = 0.008
Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Query: 393 LVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVS 452
L Y+ DG+ L ++ D+ + +++S + + VKR KGH + GP + V +
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDS---ETGERVKRLKGHTSFVNSCYPARRGP--QLVCT 169
Query: 453 GSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
GSD G + LW+ IQ + V + + + + G+D+D+K+W
Sbjct: 170 GSDDGTVKLWDIRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVW 220
Score = 35.0 bits (79), Expect = 0.20
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 184 RLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWD---WVRRQPVLDFESGHKSNVF 240
+L + + GH V L + G++L S + D V VWD + ++ + G+ N F
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHN-F 284
Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300
+ L S + A R + T + ++ H G+ +++A PD P +
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEP-III 343
Query: 301 SAGED 305
SA D
Sbjct: 344 SASSD 348
>gi|8922301 WD repeat domain 70 [Homo sapiens]
Length = 654
Score = 50.8 bits (120), Expect = 3e-06
Identities = 109/593 (18%), Positives = 207/593 (34%), Gaps = 108/593 (18%)
Query: 18 SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKD 77
++ S + + E+ E + E+ + + T R ++S DT SS ++
Sbjct: 50 AVERSRKTLEAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQS 109
Query: 78 SDSMEDT------------GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
SDS +D + +E+ + EEEEE EEE+ + ++
Sbjct: 110 SDSSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHK 169
Query: 126 DQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRL 185
DS + L
Sbjct: 170 IPDSHE---------------------------------------------------ITL 178
Query: 186 QHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLD-FESGHKSNVFQAKF 244
+HG T V+ L + G L +G D V WD+ F S Q K
Sbjct: 179 KHG----TKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234
Query: 245 LP--NSGDSTLAMCARDGQVRVAE---LSATQCCKNTKRVAQ------HKGASHKLALEP 293
L N+GD L + Q +V + +C K + + H H + P
Sbjct: 235 LQYSNTGDMILVVSG-SSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHP 293
Query: 294 DSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRD 353
F++ DA V T ++ + + + + K + T + + A ++
Sbjct: 294 KIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353
Query: 354 QFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYL 413
++I+D+ N V KF H+ +S + +C+ +S+DG L + D+ + L
Sbjct: 354 GSIQIWDR-------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKL 404
Query: 414 FNSSHSDGAQYVKRYKGHRNNATVKGVN--FYGPKSEFVVSGSD------CGHIFLWEKS 465
+ D Q+ K T+ + + P + +V+G+ G + +E+
Sbjct: 405 W-----DIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459
Query: 466 SCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLK-DVIKK 524
+ Q + ++ VV CL HP L + + K++ + + G K V+K
Sbjct: 460 TFQRVYEIDITDASVVRCLW-HPKLNQIMVGTGNGLAKVY---YDPNKSQRGAKLCVVKT 515
Query: 525 NKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESP 577
++ + ++L Q + H L + RQR ++ + + + E P
Sbjct: 516 QRKAKQAETLTQDYIITPHAL-PMFREPRQRSTRKQLEKDRLDPLKSHKPEPP 567
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 15 ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73
A+ S SS EE++ E G + +G S + D+ G N T E G + +
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212
Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132
E+ + D+ ED +E + EEEEEEEEEEE EQ R +K D D+ +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269
Score = 50.1 bits (118), Expect = 6e-06
Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81
E G E R S + +++ G D G + + T+ E G ++D +
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135
E+ + DE D EEEEEEEEEEEEE+ Q +R +++ + D R+
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Score = 39.3 bits (90), Expect = 0.010
Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 59 RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110
R S S+ + E + E+ SD S ++ G+ + N+E V + EE+EE EE+ EE
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221
Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143
+E+ + + +++ ++E E++ E
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%)
Query: 15 ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73
A+ S SS EE++ E G + +G S + D+ G N T E G + +
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212
Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132
E+ + D+ ED +E + EEEEEEEEEEE EQ R +K D D+ +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269
Score = 50.1 bits (118), Expect = 6e-06
Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 25 EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81
E G E R S + +++ G D G + + T+ E G ++D +
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212
Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135
E+ + DE D EEEEEEEEEEEEE+ Q +R +++ + D R+
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Score = 39.3 bits (90), Expect = 0.010
Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%)
Query: 59 RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110
R S S+ + E + E+ SD S ++ G+ + N+E V + EE+EE EE+ EE
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221
Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143
+E+ + + +++ ++E E++ E
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
GH + TL ++Q G LASGS D ++VWD + + + GHK + QA FL
Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLK-GHKDAITQALFLREK-- 161
Query: 251 STLAMCARDGQVRVAELSATQCCK 274
+ L +D V+ +L C K
Sbjct: 162 NLLVTSGKDTMVKWWDLDTQHCFK 185
Score = 40.4 bits (93), Expect = 0.005
Identities = 68/325 (20%), Positives = 131/325 (40%), Gaps = 35/325 (10%)
Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
GH V TL F+ + S + D + +W+ Q + + F F+P GD
Sbjct: 413 GHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSF---FVP--GD 466
Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV-- 308
+ + + G++++ +L++ + + H GA ++L PD F++ G D V
Sbjct: 467 RQVVIGTKTGKLQLYDLASGNLLET---IDAHDGALWSMSLSPDQR-GFVTGGADKSVKF 522
Query: 309 --FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPA-NTHQFAVGGRDQFVRIYDQRKID 365
F + ++ +L V + + ++ + V+ + N AV D V+I+ +D
Sbjct: 523 WDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIF---YVD 579
Query: 366 ENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYV 425
LK F + K + C+ SHDG + D ++ ++ D + +
Sbjct: 580 ------TLKFFLSLY----GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSL 629
Query: 426 KRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLE 485
++ +V + F PKS + I W+ + IQ +EG + CL
Sbjct: 630 -----FAHDDSVMYLQFV-PKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIW-CLA 682
Query: 486 PHPHLPVLATSGLDHDVKIWAPTAE 510
P + +S D +++W T E
Sbjct: 683 VSPSGDYVVSSSHDKSLRLWERTRE 707
Score = 40.0 bits (92), Expect = 0.006
Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 7/119 (5%)
Query: 387 KANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPK 446
K +TCL S DG L Y D I +F+ +G + GH+ T + G +
Sbjct: 65 KQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGN---VTFNGHKAAITTLKYDQLGGR 121
Query: 447 SEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
+ SGS I +W+ + + ++G K + L +L TSG D VK W
Sbjct: 122 ---LASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLR-EKNLLVTSGKDTMVKWW 176
Score = 30.4 bits (67), Expect = 4.8
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 440 VNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLD 499
V G K +V + C H+F+W+ + I ++G K V CL P P LA D
Sbjct: 29 VTLRGEKGRYVAVPA-CEHVFIWDLRKGEKILILQGLK-QEVTCLCPSPDGLHLAVGYED 86
Query: 500 HDVKIWA-PTAEASTELTGLKDVIKKNKRER 529
++I++ + E + G K I K ++
Sbjct: 87 GSIRIFSLLSGEGNVTFNGHKAAITTLKYDQ 117
Score = 30.0 bits (66), Expect = 6.3
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 14/82 (17%)
Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232
C ++F V + L GH V + + G +A+GS D V +W LDF
Sbjct: 571 CTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWG-------LDFG 623
Query: 233 SGHKS------NVFQAKFLPNS 248
HKS +V +F+P S
Sbjct: 624 DCHKSLFAHDDSVMYLQFVPKS 645
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 48.1 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 4/144 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS + S + E ++S + ++SD S S + + S
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN----SSDS 726
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ S DS D+ + S + ++ S + + + +
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSS 810
Score = 47.0 bits (110), Expect = 5e-05
Identities = 28/140 (20%), Positives = 62/140 (44%), Gaps = 5/140 (3%)
Query: 6 SSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESR 65
S++D +NG+ ++ ++ ++ G+ S + ++SD S S D + +S +
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 66 GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
+D++SS D S D+ +D + D S+ + + + + + ++
Sbjct: 577 SSDSDSSDSDSSDSSDSDS-----SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 126 DQDSSDDERALEDWVSSETS 145
D SD + D SS++S
Sbjct: 632 DSSDSDSKSDSSDSNSSDSS 651
Score = 46.2 bits (108), Expect = 9e-05
Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + + ++ + S +SD S S DG + +S
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +++ S + DS + D+ S ++E+ S + + + +
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
+N DSS+ + ++ SS++S
Sbjct: 917 SSN-SSDSSESSNSSDNSNSSDSS 939
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 2/146 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D +N S SS + S + + +S S E+SD S S D +
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167
Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S++S +D+ +S + DS D+ S + ++ S + + + +
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227
Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145
+N DSSD + + SS++S
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSS 1253
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S++ +D ++ S SSS + S + + ++S S E+SD S S + D +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS-SDSDSSDSSD 717
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S+ S +D++SS SDS + +D + D S+ + + +
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
+N DS+D + + SS +S
Sbjct: 778 DSSN-SSDSNDSSNSSDSSDSSNSS 801
Score = 45.4 bits (106), Expect = 1e-04
Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D +N S SS+ + S + + ++S S ++SD S S D +
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S++S +D+ S + +S D+ + S + ++ S + + + +
Sbjct: 1069 SSDS--SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SSE+S
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESS 1151
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 6/149 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
S S+D + +N S S S S + + ++ S +SD S S D + S
Sbjct: 561 SDSSDSSDSDSSDSNSS-SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE-----EEEEEEEEEEEEQPRR 116
++S+ ++S + DSDS D+ + +D + D S+ + + +
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + E SS++S
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 5/149 (3%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S ++ ++ ++ S SS+ + S + + ++S + ++S+ S S D + S
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYS----INDENRVHDRSEEEEEEEEEEEEEQPRRR 117
++S + S G D DS + D+ + S +D + D S+ + E +
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 118 VQRKRANRDQ-DSSDDERALEDWVSSETS 145
+ D +SSD + SSE+S
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESS 927
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/144 (21%), Positives = 57/144 (39%), Gaps = 2/144 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S +D +N S SS + S + + +S +SD S S + D + +S
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN--SSDSSDSNSSDSSDSSNSS 983
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ S + DS + D+ S + ++ S + +
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSS 1067
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/144 (22%), Positives = 62/144 (43%), Gaps = 2/144 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS+ + S + + S ++SD S S D + S
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
++S + ++SS SDS + + +D + D S+ + + + +
Sbjct: 1004 SDSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSS 1061
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SSE+S
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESS 1085
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 9/130 (6%)
Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
S S + +D ++ S SS + S + + + SS E ++SD D + +S
Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 63 ESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ +S DS DS + + S +D + D S+ + E +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD------ 706
Query: 122 RANRDQDSSD 131
+ D DSSD
Sbjct: 707 --SSDSDSSD 714
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 14/145 (9%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS + S + + ++S+ + +SD S S D + +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S S +D+ S DS D+ S +D + D S + + +
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD----------- 872
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + E SS++S
Sbjct: 873 --SSNSSDSSDSSDSNESSNSSDSS 895
Score = 43.1 bits (100), Expect = 7e-04
Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 6/148 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57
SS S + +D +N S SS + S + + ++S S ++SD S S D
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
+ S++S +D+ S + DS + D+ S + ++ S + + E +
Sbjct: 1102 SSDSSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + SS++S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187
Score = 43.1 bits (100), Expect = 7e-04
Identities = 32/141 (22%), Positives = 57/141 (40%), Gaps = 6/141 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57
SS S + +D +N S SS E S + + ++S S ++SD S S D
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
+ S++S +D+ S + DS D+ S + ++ S + + E +
Sbjct: 1186 SSDSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 118 VQRKRANRDQDSSDDERALED 138
++ DSSD + D
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSD 1264
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS + S + + ++S + +SD S S D + S
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDS 1222
Query: 62 TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
++S +D+ S E D SDS + + + +D + D S+ + +E + +
Sbjct: 1223 SDS--SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280
Query: 121 KRANRDQDS--SDDERALED 138
++ D DS SD + D
Sbjct: 1281 NGSDSDSDSEGSDSNHSTSD 1300
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/144 (20%), Positives = 59/144 (40%), Gaps = 1/144 (0%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
S KG S +D ++ S SS + S ++ SS + ++SD S + D + ++
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS-DSDSSDSDSSDSSDSDSSDSSN 600
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
+ ++SS SDS + S ++ + S+ + + +
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSS 684
Score = 42.7 bits (99), Expect = 0.001
Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 4/146 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + S + +G ++ S ++S+ S S D + S
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
++S ++ ESS SDS + S +D + D S+ + E
Sbjct: 880 SDSSDSN-ESSNSSDSSDSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 122 RANR--DQDSSDDERALEDWVSSETS 145
+N DSSD + + SS++S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSS 963
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/144 (22%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS +S+D +D +N S SS + S + + ++S+ +SD S S D + +S
Sbjct: 968 SSDSNSSDS-SDSSNSSDSSDSSDSSDSSDSSDSSN-----SSDSSDS--SDSSDSSNSS 1019
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ +S + DS D+ S + ++ S + + + +
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSS 1103
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/145 (21%), Positives = 61/145 (42%), Gaps = 6/145 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS+ + S + + ++S ++SD S S D + S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS-----DSSDSSDSSDSSDSSDSSNS 1057
Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
++S +D+ S + DS D+ S + ++ S + + + +
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS +S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSS 1142
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 12/148 (8%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS + S ++ + S ++SD S S D +
Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850
Query: 62 TES----RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
++S R + SS SDS + +D N + S+ + + +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD--- 907
Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS +S
Sbjct: 908 -----SSNSSDSSDSSNSSDSSESSNSS 930
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 2/146 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS + S + E ++S S ++SD S S D +
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113
Query: 61 STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S++S + S S + DS D+ + S + ++ S + + + +
Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173
Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSS 1199
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS+ + S + + ++S S ++SD S S D +
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S++S +D+ S + DS + D+ S + ++ S + + + +
Sbjct: 1162 SSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSS 1244
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 4/144 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS+ + S + E ++S + +SD S S D + +S
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD--SSDSSDS--SDSSDSSDSS 1175
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ S + DS D+ S + ++ S + + + + +
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSS 1259
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%)
Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
S S +D ++D ++ + S S + ++ ++S ++SD S S + D + S+
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690
Query: 63 ESRGTD--TESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
+S + +ESS SDS S N + D S + + +
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS-DS 749
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSS 774
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/136 (19%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 2 SSKGSSTDGRTDLANGS------LSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDG 55
SS S + +D ++GS S S ++ ++S ++SD + S D
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894
Query: 56 GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115
+ S++S +D+ +S + DS + D+ S + +N S + + +
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954
Query: 116 RRVQRKRANRDQDSSD 131
++ DSSD
Sbjct: 955 DSSNSSDSSNSSDSSD 970
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 2/147 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS + S + + ++S S ++SD S S D +
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212
Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S++S +D+ S + DS+ D+ S + ++ S + + + + Q
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Query: 120 RKRANRDQDSSDDERALEDWVSSETSA 146
K N + + SD + E S+ +++
Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 14/144 (9%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS+ + S + + +S +SD S S D + +S
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN--SSDSSNSSDSSDSNSSDSS 977
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ S + DS D+ + S D + D S+ + +
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSS--DSSDSSDSSDSSNSSDSSNSSD--------- 1026
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1027 -SSNSSDSSDSSDSSDSSDSSDSS 1049
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + S + + ++S + +SD S S D + S
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDS 1087
Query: 62 TE-SRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
++ S +D+ S + DS D+ S + ++ S + + + +
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSS 1172
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 4/144 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + S + + ++S + +SD S S D + S
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSNS 1123
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
++S +D+ S + DS + D+ S + ++ S + + + +
Sbjct: 1124 SDS--SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSS 1205
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/144 (21%), Positives = 61/144 (42%), Gaps = 7/144 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS + S + + ++S ++SD S S D + S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS-----DSSDSSDSSNSSDSSDSSDS 1132
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
++S +D+ +S + DS D+ S + ++ S + + +
Sbjct: 1133 SDS--SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSS 1214
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/145 (20%), Positives = 62/145 (42%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + S + + ++S + +SD S S D + S
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDSSDSSESSDS 1153
Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
++S +D+ S + DS D+ + S + ++ S + + + +
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSS 1238
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/146 (21%), Positives = 61/146 (41%), Gaps = 4/146 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D +N S SS + S + + ++S + S S S + D + +S
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSS 795
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ +S + DS D+ + +D + D S+ + + +
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS-DSD 854
Query: 122 RANRDQD--SSDDERALEDWVSSETS 145
+NR SSD + + SS++S
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSS 880
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D +N S SS + S + + +S S +SD S S D +
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S++S + S DS + D+ +D + D S+ + + + + R
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDS-----SDSSNSSDSSDSSDSSDGSDSDSS--NRSDS 861
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS+++
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSN 886
Score = 40.8 bits (94), Expect = 0.004
Identities = 27/144 (18%), Positives = 55/144 (38%), Gaps = 2/144 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
S+ S+D + S S + ++ + S ++SD S S D + +S
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS--SDSSNSSDSS 1028
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +D+ S + DS D+ S + ++ S + + + +
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSS 1112
Score = 40.8 bits (94), Expect = 0.004
Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S++ +D ++ S SS + S + + +S S ++SD S S D +
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083
Query: 61 STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S++S + S S + DS D+ S + ++ S + + + +
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSS 1169
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60
SS S + +D +N S SS + S + ++S+ + +SD S S D +
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S++S +D+ +S + DS D+ S + ++ S + + +
Sbjct: 1048 SSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + SS++S
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSS 1130
Score = 40.4 bits (93), Expect = 0.005
Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS+ + S + + ++S + +SD S S D + S
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSDSSDSSNS 1093
Query: 62 TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
++S +D+ S + DS D+ S + ++ S + + +
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSS 1178
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 3/145 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS E S + + +S S ++SD S S D + +
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS--SDSSDSSDS 1117
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S S +D+ S + DS ++ S + E+ S + + + +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSS 1202
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS + S + + +S S ++SD S S D +
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Query: 61 STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S++S +D+ S + DS D+ S + ++ S + + + +
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Query: 120 RKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + S+E+S
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESS 1235
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 9/153 (5%)
Query: 2 SSKGSSTD--GRTDLANGSLSSSPEEMSGAEEGRETS-------SGIEVEASDLSLSLTG 52
SS S+D +D ++ S SS E S + + +S S ++S+ S S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 53 DDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEE 112
D + S++S +D+ S DS D+ S + ++ S + + +
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 113 QPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 9/145 (6%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S +D +N S SS + S + + +S S ++SD S S + +
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S++S +D+ S SDS + + +D + D S+ + + +
Sbjct: 707 SSDSDSSDSSDSSNSNSSDS-DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS------- 758
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS +S
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSS 783
Score = 38.9 bits (89), Expect = 0.014
Identities = 33/158 (20%), Positives = 65/158 (41%), Gaps = 15/158 (9%)
Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSL----------T 51
S S++ +D +N S SS + S + + ++S S ++SD S S +
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 52 GDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE----EEEEEEE 107
D + +S S +D+ +S + DS D+ + +D + D S+ + +
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 108 EEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
+ + R ++ DSSD + SS++S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883
Score = 38.9 bits (89), Expect = 0.014
Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 6/145 (4%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60
SS S++ +D ++ S SS + S + + ++S+ + ++SD S S + +
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
S+ES + ++SS SDS + + +D + D S+ + + + +
Sbjct: 1147 SSESSDS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DS 1201
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSS 1226
Score = 38.9 bits (89), Expect = 0.014
Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 3/132 (2%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + +D ++ S SS + S + + ++S+ + +SD S S D + S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDS 1201
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
++S + ++SS SDS + + +D N D S+ + + +
Sbjct: 1202 SDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Query: 122 RANRDQDSSDDE 133
+ D SD +
Sbjct: 1261 STSDSNDESDSQ 1272
Score = 38.5 bits (88), Expect = 0.018
Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 10/144 (6%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S++ D +N S SS S + ++S ++SD S S + + + +S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS-----DSSDSSDSDSSNSSDSSNSS 830
Query: 62 TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
S +++ S + DS D+ + +D + D S+ + + +
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS----DSN 886
Query: 122 RANRDQDSSDDERALEDWVSSETS 145
++ DSSD + D SS++S
Sbjct: 887 ESSNSSDSSDSSNS-SDSDSSDSS 909
Score = 38.1 bits (87), Expect = 0.023
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS E S + + ++S S ++SD S S + +
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDE 92
++S+ + ++G D DSDS ++S +D+
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 37.4 bits (85), Expect = 0.040
Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S + ++ ++ S SS E S + + ++S+ + ++SD S S D + S
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923
Query: 62 TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
+ES +S ++ + SDS + +D + D S + + +
Sbjct: 924 SES-----SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS--NSSDS 976
Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSS 1001
Score = 37.0 bits (84), Expect = 0.052
Identities = 30/149 (20%), Positives = 61/149 (40%), Gaps = 9/149 (6%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
SS S +D + + +SS + S + + ++S+ + +SD S S D + S
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDS 761
Query: 62 TESRGT-----DTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRR 116
+ S + ++SS SDS + + +D + D S + + + +
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145
++ DSSD + + SS++S
Sbjct: 822 --NSSDSSNSSDSSDSSNSSDSSDSSDSS 848
Score = 36.6 bits (83), Expect = 0.067
Identities = 31/157 (19%), Positives = 58/157 (36%), Gaps = 12/157 (7%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEG----------RETSSGIEVEASDLSLSLT 51
SS S + +D +N S SS + S ++ ++ S ++SD S S
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 52 GDDGGPNRTSTESRGTDTESSGED--KDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEE 109
D + S++S + S+ D SDS + + + +D N + S+ + +
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 110 EEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSA 146
++ D +S D D S S+
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/110 (21%), Positives = 49/110 (44%), Gaps = 1/110 (0%)
Query: 2 SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60
SS S + +D ++ S SS + S + + ++S + E+SD S S D +
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251
Query: 61 STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEE 110
S++S + +S + +SDS +G+ + N + D + ++
Sbjct: 1252 SSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 35.4 bits (80), Expect = 0.15
Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 10/154 (6%)
Query: 3 SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLS-LSLTGDDGGPNRT 60
S S++ +D +N S SS + S + + ++S+ + ++SD S S + D + +
Sbjct: 968 SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027
Query: 61 STESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
S S +D+ S + DS DS + + + +D + D S+ + + + +
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 120 RKRANR-------DQDSSDDERALEDWVSSETSA 146
+N D S D D S S+
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Score = 35.0 bits (79), Expect = 0.20
Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 9/151 (5%)
Query: 5 GSSTDGRTDLANG--SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
G S G ++G S + M G + S +A+ S + + G + S
Sbjct: 437 GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496
Query: 63 ESR--GTDTESSG-EDKDSDSMEDTGHYSI----NDENRVHDRSEEEEEEEEEEEEEQPR 115
ES+ G ++S G ED DSDS DT + N+ N +D+S+ + + + + +
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556
Query: 116 RRVQRKRANRDQDSSDDERALEDWVSSETSA 146
++ S D + D SS++ +
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587
Score = 33.5 bits (75), Expect = 0.57
Identities = 31/148 (20%), Positives = 62/148 (41%), Gaps = 26/148 (17%)
Query: 2 SSKGSST---DGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPN 58
SS+G ++ D D NGS + GAE+ S+ + ++ + G++G +
Sbjct: 486 SSRGDASYNSDESKDNGNGS------DSKGAEDDDSDSTS---DTNNSDSNGNGNNGNDD 536
Query: 59 RTSTES-RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
++S +G S + DS + D+ S +D + + S+ + + + +
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS----- 591
Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145
D DSSD + + SS++S
Sbjct: 592 --------DSDSSDSSNSSDSSDSSDSS 611
Score = 31.2 bits (69), Expect = 2.8
Identities = 23/146 (15%), Positives = 57/146 (39%), Gaps = 18/146 (12%)
Query: 1 MSSKGSSTDGRTDLAN------GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDD 54
++ +STD ++ G+ S +++ G + + D L D
Sbjct: 186 VAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLD--NSD 243
Query: 55 GGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEE----------E 104
G P+ + + ED+++ + +D+ + S E + H + ++ + E
Sbjct: 244 GSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKE 303
Query: 105 EEEEEEEEQPRRRVQRKRANRDQDSS 130
+ E +E P V + ++ +++S
Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENS 329
Score = 29.6 bits (65), Expect = 8.2
Identities = 28/146 (19%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 17 GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDK 76
G +S +E +G ++ S D S + D+ N ++S+G + + S
Sbjct: 462 GDDPNSSDESNGNDDANSESDNNSSSRGDASYN--SDESKDNGNGSDSKGAEDDDSDSTS 519
Query: 77 DSDSMEDTGHYSI-NDENRVHDR--------------SEEEEEEEEEEEEEQPRRRVQRK 121
D+++ + G+ + ND+N D S + + + +
Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579
Query: 122 RANRDQDSSD--DERALEDWVSSETS 145
+ D DSSD D + + SS++S
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSS 605
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 11/173 (6%)
Query: 1 MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60
MSS S G G + + ++ A+ GR+ + + SD DDG
Sbjct: 216 MSSDASDASGEE---GGRVPKAKKKAPLAKGGRKKK---KKKGSDDEAFEDSDDGDFEGQ 269
Query: 61 STESRGTDTESSGEDKDSDS---MEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
+ + SS E+ +S + ++ G +++++ + SEEE+ EE++EEE+ ++
Sbjct: 270 EVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKA 329
Query: 118 VQRKRANRDQDSSDDERALE--DWVSSETSALPRPRWQALPALRERELGSSAR 168
+ R +DSS++ + E D S +SAL + + P + G S+R
Sbjct: 330 PTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSR 382
Score = 34.7 bits (78), Expect = 0.26
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 3/97 (3%)
Query: 58 NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
N T T T E++ + H+SI + R+ D+ ++E +EEE+E++ RR+
Sbjct: 145 NFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDE---DEEEKEKRGRRK 201
Query: 118 VQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQA 154
R + +D + D E +P+ + +A
Sbjct: 202 ASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKA 238
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 47.0 bits (110), Expect = 5e-05
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 16/110 (14%)
Query: 22 SPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSM 81
S E+ G +E E G + E D D+ G E D + G++ D +
Sbjct: 158 SDAEVDGVDEEEEDEEGEDEEDED-------DEDGEEEEFDEEDDEDEDVEGDEDDDEVS 210
Query: 82 EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSD 131
E+ + ++ EE+E+E+E+EEEE+ + +RKR D+ D
Sbjct: 211 EEEEEFGLD---------EEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 37.4 bits (85), Expect = 0.040
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 56 GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115
G +R E+ +D E G D++ + E +DE+ + +EE++E+E+ E ++
Sbjct: 147 GYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD 206
Query: 116 RRVQRKRA-----NRDQDSSDDERALE 137
V + D+D +DE E
Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEE 233
Score = 30.8 bits (68), Expect = 3.7
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 66 GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
G D E E DSD+ D DE + E+EE+E++E+ EE+ + +
Sbjct: 147 GYDREDQ-EAPDSDAEVDGV-----DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200
Query: 126 DQDSSDDERALED 138
+ D DDE + E+
Sbjct: 201 EGDEDDDEVSEEE 213
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 6/130 (4%)
Query: 190 EGHTGCVNTLHFNQR-GTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
EGHT V L +N+ LAS S D V++WD +P + H V +F P
Sbjct: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311
Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308
TL + D V + + + + R+ + G ++ SPC FL++ +D V
Sbjct: 312 AQ-TLISGSYDKSVALYDCRSPD---ESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFV 367
Query: 309 FTIDLRQDRP 318
+ +D R D+P
Sbjct: 368 YNLDARSDKP 377
Score = 35.8 bits (81), Expect = 0.11
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 42/216 (19%)
Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
SA D V D+ +PA+ L V +K + T+ +P G D+ V +YD
Sbjct: 274 SASADNTVILWDMSLGKPAASLAVHTDK-----VQTLQFHPFEAQTLISGSYDKSVALYD 328
Query: 361 QRKIDENEN----NGVLKK-----FCPHHLVNSESKANITCLVYSHDGTELLASYNDEDI 411
R DE+ +G +++ F P H + S VY+ D + +D+ I
Sbjct: 329 CRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG----FVYNLD------ARSDKPI 378
Query: 412 YLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQ 471
+ N+ +N + G++ +V+ S ++ +W+ +
Sbjct: 379 FTLNA----------------HNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSL 422
Query: 472 FMEGD-KGGVVNCLEPHPHLP-VLATSGLDHDVKIW 505
D K GV+ C P LP + A G +++W
Sbjct: 423 VHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVW 458
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 46.6 bits (109), Expect = 7e-05
Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Query: 41 VEASDLSLSL--TGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDR 98
VE SD++ G GGPN T T T +S GE+++ + E+ +E
Sbjct: 375 VEPSDIAACFREAGFGGGPNATIT----TSLKSEGEEEEEEEEEE-------EEEEGEGE 423
Query: 99 SEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSS 142
EEEE EEEEEE + + + + D DE ED SS
Sbjct: 424 EEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467
Score = 34.7 bits (78), Expect = 0.26
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 15/101 (14%)
Query: 17 GSLSSSPEEMSGAEEGRETSS-GIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE--SSG 73
G + S EE EE E+SS G+E E + G G E++ G
Sbjct: 452 GDVDSDEEE----EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507
Query: 74 EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQP 114
ED DSDS E+ ++ D +E+++++EE+ +E P
Sbjct: 508 EDSDSDSEEE--------DDEEEDDEDEDDDDDEEDGDEVP 540
>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
Length = 1495
Score = 46.6 bits (109), Expect = 7e-05
Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 21/136 (15%)
Query: 54 DGGPNRTSTESRGTDTESSGEDKDSDSMEDT-------GHYSINDENRVHDR---SEEEE 103
+G N T+ E G T + D D +S E T H++ + + + + EEEE
Sbjct: 790 EGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEMIPSDEEEE 849
Query: 104 EEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALREREL 163
++EEEEEEE+PR + +R + D +++DE S + AL + EL
Sbjct: 850 DDEEEEEEEEPRLTI-NQREDEDGMANEDELDNTYTGSGDEDALSE---------EDDEL 899
Query: 164 GSSARFV-YEACGARV 178
G +A++ + CG V
Sbjct: 900 GEAAKYEDVKECGKHV 915
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 46.6 bits (109), Expect = 7e-05
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
GH G V +L F+ G +LAS +D ++ +WD + GH N+ F P+SG
Sbjct: 466 GHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELR-GHTDNITSLTFSPDSG- 523
Query: 251 STLAMCARDGQVRVAELSATQC 272
+A + D VRV ++ T C
Sbjct: 524 -LIASASMDNSVRVWDIRNTYC 544
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 13/173 (7%)
Query: 190 EGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSG 249
+GH V L + + ASGS D +W + R P L +GH ++V KF PNS
Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP-LRIYAGHLADVDCVKFHPNS- 438
Query: 250 DSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVF 309
+ LA + D VR L + Q + + H+G LA P+ SAGED +
Sbjct: 439 -NYLATGSTDKTVR---LWSAQQGNSVRLFTGHRGPVLSLAFSPNGK-YLASAGEDQRLK 493
Query: 310 TIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQR 362
DL + KE T ++ A D VR++D R
Sbjct: 494 LWDLASG------TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540
Score = 39.7 bits (91), Expect = 0.008
Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 9/157 (5%)
Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
GH V+ + F+ +LA+GS D V +W + V F +GH+ V F PN
Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF-TGHRGPVLSLAFSPNG-- 480
Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFT 310
LA D ++++ +L++ K + H L PDS SA D V
Sbjct: 481 KYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSG-LIASASMDNSVRV 536
Query: 311 IDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQF 347
D+R ++ + VG+YT ++ + QF
Sbjct: 537 WDIRNTYCSAP--ADGSSSELVGVYTGQMSNVLSVQF 571
Score = 37.4 bits (85), Expect = 0.040
Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 18/152 (11%)
Query: 396 SHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSD 455
SHD T L S+ D ++ Y GH A V V F+ P S ++ +GS
Sbjct: 403 SHDRTARLWSF-------------DRTYPLRIYAGHL--ADVDCVKFH-PNSNYLATGST 446
Query: 456 CGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW-APTAEASTE 514
+ LW ++ G +G V++ L P+ LA++G D +K+W + E
Sbjct: 447 DKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 505
Query: 515 LTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
L G D I D + + +S +W
Sbjct: 506 LRGHTDNITSLTFSPDSGLIASASMDNSVRVW 537
Score = 30.4 bits (67), Expect = 4.8
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504
P S + SGS LW ++ G V +C++ HP+ LAT D V++
Sbjct: 394 PYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV-DCVKFHPNSNYLATGSTDKTVRL 452
Query: 505 WAPTAEASTEL 515
W+ S L
Sbjct: 453 WSAQQGNSVRL 463
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,171,101
Number of Sequences: 37866
Number of extensions: 1254478
Number of successful extensions: 27620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 636
Number of HSP's successfully gapped in prelim test: 460
Number of HSP's that attempted gapping in prelim test: 11601
Number of HSP's gapped (non-prelim): 8276
length of query: 597
length of database: 18,247,518
effective HSP length: 108
effective length of query: 489
effective length of database: 14,157,990
effective search space: 6923257110
effective search space used: 6923257110
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.