Guide to the Human Genome
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Search of human proteins with 30089954

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30089954 H326 [Homo sapiens]
         (597 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30089954 H326 [Homo sapiens]                                      1224   0.0  
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...   845   0.0  
gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]   795   0.0  
gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]        145   8e-35
gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]        145   8e-35
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]         134   3e-31
gi|55741849 WD repeat domain 22 [Homo sapiens]                         99   8e-21
gi|16554629 WD repeat domain 5 [Homo sapiens]                          74   5e-13
gi|16554627 WD repeat domain 5 [Homo sapiens]                          74   5e-13
gi|23199987 WD repeat domain 5B [Homo sapiens]                         66   1e-10
gi|147904340 WD repeat domain 82 [Homo sapiens]                        62   2e-09
gi|19913369 transducin beta-like 3 [Homo sapiens]                      57   5e-08
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ...    57   6e-08
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s...    57   6e-08
gi|7706657 cell division cycle 40 homolog [Homo sapiens]               53   7e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    53   9e-07
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]      52   1e-06
gi|113865883 WD repeat domain 38 [Homo sapiens]                        51   3e-06
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]    51   3e-06
gi|8922301 WD repeat domain 70 [Homo sapiens]                          51   3e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           50   5e-06
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           50   5e-06
gi|5803221 WD repeat-containing protein 3 [Homo sapiens]               49   2e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    48   2e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    48   3e-05
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    47   5e-05
gi|5902034 periodic tryptophan protein 1 [Homo sapiens]                47   5e-05
gi|21735415 centromere protein B [Homo sapiens]                        47   7e-05
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]       47   7e-05
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]     47   7e-05

>gi|30089954 H326 [Homo sapiens]
          Length = 597

 Score = 1224 bits (3166), Expect = 0.0
 Identities = 597/597 (100%), Positives = 597/597 (100%)

Query: 1   MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60
           MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT
Sbjct: 1   MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60

Query: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR
Sbjct: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120

Query: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180
           KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV
Sbjct: 121 KRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFV 180

Query: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240
           QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF
Sbjct: 181 QRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVF 240

Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300
           QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL
Sbjct: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300

Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
           SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD
Sbjct: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360

Query: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420
           QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD
Sbjct: 361 QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSD 420

Query: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480
           GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV
Sbjct: 421 GAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGV 480

Query: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540
           VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF
Sbjct: 481 VNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLF 540

Query: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
           DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS
Sbjct: 541 DSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score =  845 bits (2183), Expect = 0.0
 Identities = 426/632 (67%), Positives = 489/632 (77%), Gaps = 36/632 (5%)

Query: 1   MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD-----DG 55
           MS +  STDG  DL   SL SSPEE SGA    E SS I++  S+LS+++TGD     DG
Sbjct: 1   MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDG 60

Query: 56  G-PNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVH------------------ 96
           G PN  STE+R +D ES+ ED + +S+ED  H+ ++ E+  H                  
Sbjct: 61  GFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120

Query: 97  -----------DRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
                      +  EEEEEEEEEEEEEQPR   Q    N +Q S ++++ALE+WVSSETS
Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETS 180

Query: 146 ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRG 205
           ALPRPRWQ + AL +R+LGS  RFVYEACGAR FVQRFRLQ+ L  H GCVNT+HFNQRG
Sbjct: 181 ALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRG 240

Query: 206 TWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVA 265
           T LAS  DDLKV+VWDWVR++PVL+FESGH +NVFQAKFLPN GDSTLAMCARDGQVRVA
Sbjct: 241 TRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVA 300

Query: 266 ELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVT 325
           EL       NTK VAQH+G +HKLALEPDSP  FL++GEDAVVFTIDLRQDRPASK+VVT
Sbjct: 301 ELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVT 360

Query: 326 KEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSE 385
           +E +KKVGLYTI VNPANT+QFAVGG+DQFVRIYDQRKID+ ENNGVLKKF PHHLVN +
Sbjct: 361 RENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCD 420

Query: 386 SKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGP 445
              NITC+VYSHDGTELLASYND+DIYLFNSSHSDGAQY KR+KGHRNN TVKGVNFYGP
Sbjct: 421 FPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGP 480

Query: 446 KSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
           +SEFVVSGSDCGHIF WEKSSCQIIQF++G + G +NCLEPHP+LPVLA SGLDHDVKIW
Sbjct: 481 RSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIW 540

Query: 506 APTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPG 565
            PTA+A+TELTGLK VIKKNK ERDEDSLH   LFD +MLWFL+ H+ QR  H+ WR   
Sbjct: 541 TPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGE 600

Query: 566 VGATDADSDESPSSSDTSDEEEGPDRVQCMPS 597
               D +SDES S+S+TS EEE  DRVQCMPS
Sbjct: 601 AEFPDEESDESSSTSETS-EEEVQDRVQCMPS 631


>gi|62988359 DDB1 and CUL4 associated factor 8-like 1 [Homo sapiens]
          Length = 600

 Score =  795 bits (2052), Expect = 0.0
 Identities = 410/604 (67%), Positives = 474/604 (78%), Gaps = 11/604 (1%)

Query: 1   MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGD--DGG-P 57
           MS +  ST G  DL   SL SSPEE SG       SS IE+ A++ S    GD  DGG  
Sbjct: 1   MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFL 60

Query: 58  NRTSTESRGTDTESSGEDKDSDSMEDT--GHYSINDENRVHDRSEEEEEEEEE-EEEEQP 114
           N  STE++ TD+ESS ED + +SM +   G+  + +E    +R EEEEE EEE EEEEQP
Sbjct: 61  NDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEET---EREEEEEEMEEEGEEEEQP 117

Query: 115 RRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEAC 174
           R   +    N DQ   D+++ALE+W+SSETSALPR RWQ L ALR+R+LGSSARFVYEAC
Sbjct: 118 RMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEAC 177

Query: 175 GARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESG 234
           GAR FVQRFRLQ+ L  H G V+T+HFNQRGT LAS  DDL+V+VWDWVR++PVL+FESG
Sbjct: 178 GARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESG 237

Query: 235 HKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPD 294
           H  NV QAKF PN GDSTLAMC  DGQVRVAEL     C+NTKRVA+H+G +H+LALEPD
Sbjct: 238 HDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPD 297

Query: 295 SPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQ 354
           SP  FL++GEDAVVFTIDLRQDRPASK+VVT+E +KKVGLYTI +NPAN +QFAVGG DQ
Sbjct: 298 SPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQ 357

Query: 355 FVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLF 414
           FVRIYDQR+ID+ ENNGVLKKF PHHLV  +   NITC+VYSHDGTELLASYNDEDIYLF
Sbjct: 358 FVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLF 417

Query: 415 NSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFME 474
           NSS SDGAQYVKRYKGHRNN T+K VNFYGP+SEFVVSGSDCGH+F WEKSS QIIQFME
Sbjct: 418 NSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFME 477

Query: 475 GDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSL 534
           GD+G +VNCLEPHP+LPVLATSGLD  V+IW PTA+ +TELTGLKDVIKKNK+ERDED+L
Sbjct: 478 GDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNL 537

Query: 535 HQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADS-DESPSSSDTSDEEEGPDRVQ 593
           + TD FD+ ML F + HL QR H   WR+ G    D +  DES S+SDTS EEEG DRVQ
Sbjct: 538 NYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTS-EEEGQDRVQ 596

Query: 594 CMPS 597
           C+PS
Sbjct: 597 CIPS 600


>gi|63252910 IQ motif and WD repeats 1 isoform b [Homo sapiens]
          Length = 860

 Score =  145 bits (367), Expect = 8e-35
 Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%)

Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215
           +R+R LG    +R      G R F+QR +L+  L  H GCVNT+ +N  G ++ SGSDD 
Sbjct: 14  VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73

Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275
           K+V+ +   R+ +    SGH++N+F AKFLP + D  +  C+ DG +    +        
Sbjct: 74  KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133

Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330
             +   H G ++++   P+ P TFLS GED  V   D R      K   TKE  K     
Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188

Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380
             +    ++ + P   +  AVG  D  VRIYD+R +              G++ +F P H
Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248

Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415
           L N   +  +T L YS DG E+L SY+ + IYLF+
Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281



 Score =  105 bits (262), Expect = 1e-22
 Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%)

Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
           YKGHRN+ T +K  NF+G  + FV+SGSDCGHIF+W++ + + +  +E D   VVNCL+P
Sbjct: 713 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 769

Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
           HP  P+LA+SG+D+D+KIW+P  E+      L D +        E++ +   +  S ML 
Sbjct: 770 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 829

Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575
            L  ++H+R  R     R  G G  + + DE
Sbjct: 830 MLASLNHIRADRLEGD-RSEGSGQENENEDE 859


>gi|63252908 IQ motif and WD repeats 1 isoform a [Homo sapiens]
          Length = 880

 Score =  145 bits (367), Expect = 8e-35
 Identities = 92/275 (33%), Positives = 137/275 (49%), Gaps = 24/275 (8%)

Query: 158 LRERELG--SSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDL 215
           +R+R LG    +R      G R F+QR +L+  L  H GCVNT+ +N  G ++ SGSDD 
Sbjct: 14  VRKRSLGLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGCVNTICWNDTGEYILSGSDDT 73

Query: 216 KVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN 275
           K+V+ +   R+ +    SGH++N+F AKFLP + D  +  C+ DG +    +        
Sbjct: 74  KLVISNPYSRKVLTTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGVIFYTNVEQDAETNR 133

Query: 276 TKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEK----- 330
             +   H G ++++   P+ P TFLS GED  V   D R      K   TKE  K     
Sbjct: 134 QCQFTCHYGTTYEIMTVPNDPYTFLSCGEDGTVRWFDTR-----IKTSCTKEDCKDDILI 188

Query: 331 --KVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE--------NNGVLKKFCPHH 380
             +    ++ + P   +  AVG  D  VRIYD+R +              G++ +F P H
Sbjct: 189 NCRRAATSVAICPPIPYYLAVGCSDSSVRIYDRRMLGTRATGNYAGRGTTGMVARFIPSH 248

Query: 381 LVNSESKANITCLVYSHDGTELLASYNDEDIYLFN 415
           L N   +  +T L YS DG E+L SY+ + IYLF+
Sbjct: 249 LNNKSCR--VTSLCYSEDGQEILVSYSSDYIYLFD 281



 Score =  105 bits (262), Expect = 1e-22
 Identities = 60/151 (39%), Positives = 90/151 (59%), Gaps = 7/151 (4%)

Query: 428 YKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
           YKGHRN+ T +K  NF+G  + FV+SGSDCGHIF+W++ + + +  +E D   VVNCL+P
Sbjct: 733 YKGHRNSRTMIKEANFWG--ANFVMSGSDCGHIFIWDRHTAEHLMLLEADNH-VVNCLQP 789

Query: 487 HPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
           HP  P+LA+SG+D+D+KIW+P  E+      L D +        E++ +   +  S ML 
Sbjct: 790 HPFDPILASSGIDYDIKIWSPLEESRIFNRKLADEVITRNELMLEETRNTITVPASFMLR 849

Query: 547 FL--MHHLRQRRHHRRWREPGVGATDADSDE 575
            L  ++H+R  R     R  G G  + + DE
Sbjct: 850 MLASLNHIRADRLEGD-RSEGSGQENENEDE 879


>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
          Length = 676

 Score =  134 bits (336), Expect = 3e-31
 Identities = 91/309 (29%), Positives = 145/309 (46%), Gaps = 47/309 (15%)

Query: 179 FVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSN 238
           F++R  L+  L+GH+GCVN L +N++G  LASGSDD   +VWD +  + +L   +GH +N
Sbjct: 33  FIRRLGLEAELQGHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTAN 92

Query: 239 VFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
           +F  KFLP++GD  L   A D +V V +L+  +          H     ++A  P  P T
Sbjct: 93  IFSVKFLPHAGDRILITGAADSKVHVHDLTVKE---TIHMFGDHTNRVKRIATAPMWPNT 149

Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVV--TKEKEKKVGLYTIYVNPANTHQFAVGGRDQFV 356
           F SA ED ++   DLR++   S++++  T+   + V    + VNP + +  AVG    FV
Sbjct: 150 FWSAAEDGLIRQYDLRENSKHSEVLIDLTEYCGQLVEAKCLTVNPQDNNCLAVGASGPFV 209

Query: 357 RIYDQRKIDENEN---------------------NGVLKKFCPHHL------VNSESKAN 389
           R+YD R I  +                       +G  + +   HL       N+  +  
Sbjct: 210 RLYDIRMIHNHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNNRLRVL 269

Query: 390 I-TCLVYSHDGTELLASYNDEDIYLFN--------------SSHSDGAQYVKRYKGHRNN 434
           + T + +S +GTELL +   E +YLF+                HS G Q  K      +N
Sbjct: 270 VATYVTFSPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSSGVQNGKMSTNGVSN 329

Query: 435 ATVKGVNFY 443
               G++ +
Sbjct: 330 GVSNGLHLH 338



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 38/199 (19%)

Query: 405 SYNDEDIYLFNSSHSDGAQYVKRYKGHRNNAT-VKGVNFYGPKSEFVVSGSDCGHIFLWE 463
           S +++++ L   S+     Y  RY GH N  T +K  NF+G  ++++VSGSD G  F+WE
Sbjct: 510 SISEDEMVLRERSYD----YQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWE 565

Query: 464 KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTG-----L 518
           K +  +++ ++GD+  +VNCL+PHP    LATSG+D  V++W P  E S +LTG     +
Sbjct: 566 KETTNLVRVLQGDE-SIVNCLQPHPSYCFLATSGIDPVVRLWNPRPE-SEDLTGRVVEDM 623

Query: 519 KDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPS 578
           +   + N+R  + D L    L   + +  L                G GA+D        
Sbjct: 624 EGASQANQRRMNADPLEVMLLNMGYRITGL-------------SSGGAGASD-------- 662

Query: 579 SSDTSDEEEGPDRVQCMPS 597
                DE+    +VQC PS
Sbjct: 663 -----DEDSSEGQVQCRPS 676


>gi|55741849 WD repeat domain 22 [Homo sapiens]
          Length = 942

 Score = 99.4 bits (246), Expect = 8e-21
 Identities = 84/334 (25%), Positives = 156/334 (46%), Gaps = 35/334 (10%)

Query: 189 LEGHTGCVNTLHF-NQRGTWLASGSDDLKVVVWDWVR----RQPVLDFESGHKSNVFQAK 243
           L GH GCVN + F N  G WL SG DD +V++W   +    R   +  +  H SN+F   
Sbjct: 49  LLGHFGCVNAIEFSNNGGQWLVSGGDDRRVLLWHMEQAIHSRVKPIQLKGEHHSNIFCLA 108

Query: 244 FLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAG 303
           F  NSG++ +     D QV + ++ +++    T  V  H+ A + L++ P +   F S+ 
Sbjct: 109 F--NSGNTKVFSGGNDEQVILHDVESSE----TLDVFAHEDAVYGLSVSPVNDNIFASSS 162

Query: 304 EDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRK 363
           +D  V   D+R+        +          +++  NP      A     + V ++D RK
Sbjct: 163 DDGRVLIWDIRESPHGEPFCLANYPS---AFHSVMFNPVEPRLLATANSKEGVGLWDIRK 219

Query: 364 IDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQ 423
              +     L ++  +  + S          ++ +GT+LLA        L++  HS    
Sbjct: 220 PQSS-----LLRYGGNLSLQSAMSVR-----FNSNGTQLLALRRRLPPVLYDI-HSRLPV 268

Query: 424 YVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLW----EKSSCQIIQFMEGD--- 476
           +    +G+ N+ T+K   F G + ++++SGSD  ++++W    +  +  I + + G    
Sbjct: 269 FQFDNQGYFNSCTMKSCCFAGDRDQYILSGSDDFNLYMWRIPADPEAGGIGRVVNGAFMV 328

Query: 477 -KG--GVVNCLEPHPHLPVLATSGLDHDVKIWAP 507
            KG   +VN +  +PH  ++ +SG++  +KIW+P
Sbjct: 329 LKGHRSIVNQVRFNPHTYMICSSGVEKIIKIWSP 362


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%)

Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239
           + L+  L GHT  V+++ F+  G WLAS S D  + +W     +    FE   SGHK  +
Sbjct: 35  YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90

Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
               +   S DS L + A D + +++ ++S+ +C K  K                     
Sbjct: 91  SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126

Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347
               G    VF  +     P S L+V+   ++ V ++ +           + +P +   F
Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179

Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406
              G       YD   +I +  +   LK          +    ++ + +S +G  +LA+ 
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233

Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466
            D  + L++ S     + +K Y GH+N       NF     +++VSGS+   +++W   +
Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290

Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505
            +I+Q ++G    V++    HP   ++A++ L++D  +K+W
Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 77/341 (22%), Positives = 147/341 (43%), Gaps = 63/341 (18%)

Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE---SGHKSNV 239
           + L+  L GHT  V+++ F+  G WLAS S D  + +W     +    FE   SGHK  +
Sbjct: 35  YALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGK----FEKTISGHKLGI 90

Query: 240 FQAKFLPNSGDSTLAMCARDGQ-VRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCT 298
               +   S DS L + A D + +++ ++S+ +C K  K                     
Sbjct: 91  SDVAW---SSDSNLLVSASDDKTLKIWDVSSGKCLKTLK--------------------- 126

Query: 299 FLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTI-----------YVNPANTHQF 347
               G    VF  +     P S L+V+   ++ V ++ +           + +P +   F
Sbjct: 127 ----GHSNYVFCCNFN---PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179

Query: 348 AVGGRDQFVRIYDQR-KIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASY 406
              G       YD   +I +  +   LK          +    ++ + +S +G  +LA+ 
Sbjct: 180 NRDGSLIVSSSYDGLCRIWDTASGQCLKTLI------DDDNPPVSFVKFSPNGKYILAAT 233

Query: 407 NDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSS 466
            D  + L++ S     + +K Y GH+N       NF     +++VSGS+   +++W   +
Sbjct: 234 LDNTLKLWDYSKG---KCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQT 290

Query: 467 CQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHD--VKIW 505
            +I+Q ++G    V++    HP   ++A++ L++D  +K+W
Sbjct: 291 KEIVQKLQGHTDVVIS-TACHPTENIIASAALENDKTIKLW 330


>gi|23199987 WD repeat domain 5B [Homo sapiens]
          Length = 330

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 70/328 (21%), Positives = 142/328 (43%), Gaps = 37/328 (11%)

Query: 183 FRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFES---GHKSNV 239
           + L+  L GHT  V+++ F+  G WLAS S D  +++W     +    +E    GH   +
Sbjct: 31  YALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK----YEKTLYGHNLEI 86

Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTF 299
               +  +S  S L   + D  +++ ++ + +C K  K    H          P S    
Sbjct: 87  SDVAW--SSDSSRLVSASDDKTLKLWDVRSGKCLKTLKG---HSNYVFCCNFNPPSNL-I 140

Query: 300 LSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIY 359
           +S   D  V   +++  +    L    +      +  ++ N + +     G  D   RI+
Sbjct: 141 ISGSFDETVKIWEVKTGKCLKTLSAHSDP-----VSAVHFNCSGS-LIVSGSYDGLCRIW 194

Query: 360 DQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHS 419
           D                C   LV+ ++   ++ + +S +G  +L +  D  + L++ S  
Sbjct: 195 DAASGQ-----------CLKTLVDDDNPP-VSFVKFSPNGKYILTATLDNTLKLWDYSRG 242

Query: 420 DGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGG 479
              + +K Y GH+N       NF     +++VSGS+   +++W   + +I+Q ++G    
Sbjct: 243 ---RCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299

Query: 480 VVNCLEPHPHLPVLATSGLDHD--VKIW 505
           V++    HP   ++A++ L++D  +K+W
Sbjct: 300 VISA-ACHPTENLIASAALENDKTIKLW 326


>gi|147904340 WD repeat domain 82 [Homo sapiens]
          Length = 313

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 74/338 (21%), Positives = 131/338 (38%), Gaps = 40/338 (11%)

Query: 180 VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNV 239
           ++ FR+      ++  +N   F+  G  + S SDD  +V++D    +P     S  K  V
Sbjct: 8   LRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYS-KKYGV 66

Query: 240 FQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPC-- 297
              ++   +     +    D  +R   L       + K +    G S ++     SP   
Sbjct: 67  DLIRYTHAANTVVYSSNKIDDTIRYLSLH------DNKYIRYFPGHSKRVVALSMSPVDD 120

Query: 298 TFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ-----FAVGGR 352
           TF+S   D  +   DLR                  GL  +   P  +       FA G  
Sbjct: 121 TFISGSLDKTIRLWDLRSPNCQ-------------GLMHLQGKPVCSFDPEGLIFAAGVN 167

Query: 353 DQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIY 412
            + V++YD R  D+    G    F   +    +     T L +S+DG  +L S N   I 
Sbjct: 168 SEMVKLYDLRSFDK----GPFATFKMQY----DRTCEWTGLKFSNDGKLILISTNGSFIR 219

Query: 413 LFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQF 472
           L ++        +  + G+ N+  V     + P S+F++ GS+ G I +W   S   +  
Sbjct: 220 LIDAFKG---VVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAV 276

Query: 473 MEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAE 510
           ++G   G + CL+ +P     A++    ++  W PT +
Sbjct: 277 LDGKHTGPITCLQFNPKFMTFASA--CSNMAFWLPTID 312


>gi|19913369 transducin beta-like 3 [Homo sapiens]
          Length = 808

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 78/321 (24%), Positives = 119/321 (37%), Gaps = 32/321 (9%)

Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251
           HT  V T+ F+   T LA+G  D  V VWD VR      F  G    V    F P+    
Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFR-GSPGVVHLVAFHPDPTRL 166

Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311
            L   A D  +RV  L    C      +  H  A   LA   D   T LS+G D +    
Sbjct: 167 LLFSSATDAAIRVWSLQDRSC---LAVLTAHYSAVTSLAFSADGH-TMLSSGRDKICIIW 222

Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQ----FAVGGRDQFVRIYDQRKIDEN 367
           DL+  +    + V +  E  V L    V+          F   G    +R+++       
Sbjct: 223 DLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWE------- 275

Query: 368 ENNGVLKKFCPHHLVNSESKA-NITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVK 426
                    C +           +T    +H    +L +  D ++ L+ +      +  K
Sbjct: 276 ----AASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEAR---SLRLQK 328

Query: 427 RYKGHRNNATVKGVNFYGPKSEFVV--SGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCL 484
           ++ G+  +  V  V F GP+   VV  S S C  +F  + S+CQI+         +V  L
Sbjct: 329 QFAGY--SEEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILH----GHTDIVLAL 382

Query: 485 EPHPHLPVLATSGLDHDVKIW 505
           +      + A+   D  V+IW
Sbjct: 383 DVFRKGWLFASCAKDQSVRIW 403



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 1/62 (1%)

Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504
           P  + + +GS      LW    CQ++    G + G+  C++  P   VLAT+  D  +K+
Sbjct: 489 PNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLW-CVQFSPMDQVLATASADGTIKL 547

Query: 505 WA 506
           WA
Sbjct: 548 WA 549


>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
           sapiens]
          Length = 315

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%)

Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253
           G V  + FN  G +  +   D  + +W+ +R   +L   SGH   V  A    +  +S+L
Sbjct: 26  GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82

Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313
                D  V + ++++ Q     ++   H G  + +    ++    LS   D+ +   D 
Sbjct: 83  CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138

Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373
           R  RP     V    E + G+ ++ V+    H+   G  D  VR YD R           
Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182

Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433
                  L +    + ITC  +S DG   L S  D  + L +    D  + +  YKGH+N
Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234

Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493
               K       +   VVS S+ G +F W+     +   +     GVV  L  HP  P L
Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292

Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517
            T+ +   V+ W   A  + +  G
Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223
           G  A  +++    +V V++FR      GH G VNT+ FN+  T + SGS D  +  WD  
Sbjct: 87  GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139

Query: 224 RRQP 227
            R+P
Sbjct: 140 SRRP 143


>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
           sapiens]
          Length = 315

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 78/324 (24%), Positives = 127/324 (39%), Gaps = 34/324 (10%)

Query: 194 GCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTL 253
           G V  + FN  G +  +   D  + +W+ +R   +L   SGH   V  A    +  +S+L
Sbjct: 26  GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGT-LLRTYSGHGYEVLDAA--GSFDNSSL 82

Query: 254 AMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDL 313
                D  V + ++++ Q     ++   H G  + +    ++    LS   D+ +   D 
Sbjct: 83  CSGGGDKAVVLWDVASGQV---VRKFRGHAGKVNTVQFNEEAT-VILSGSIDSSIRCWDC 138

Query: 314 RQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVL 373
           R  RP     V    E + G+ ++ V+    H+   G  D  VR YD R           
Sbjct: 139 RSRRPEP---VQTLDEARDGVSSVKVSD---HEILAGSVDGRVRRYDLRM---------- 182

Query: 374 KKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRN 433
                  L +    + ITC  +S DG   L S  D  + L +    D  + +  YKGH+N
Sbjct: 183 -----GQLFSDYVGSPITCTCFSRDGQCTLVSSLDSTLRLLD---KDTGELLGEYKGHKN 234

Query: 434 NATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVL 493
               K       +   VVS S+ G +F W+     +   +     GVV  L  HP  P L
Sbjct: 235 Q-EYKLDCCLSERDTHVVSCSEDGKVFFWDLVEGALALALPVG-SGVVQSLAYHPTEPCL 292

Query: 494 ATSGLDHDVKIWAPTAEASTELTG 517
            T+ +   V+ W   A  + +  G
Sbjct: 293 LTA-MGGSVQCWREEAYEAEDGAG 315



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 7/64 (10%)

Query: 164 GSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWV 223
           G  A  +++    +V V++FR      GH G VNT+ FN+  T + SGS D  +  WD  
Sbjct: 87  GDKAVVLWDVASGQV-VRKFR------GHAGKVNTVQFNEEATVILSGSIDSSIRCWDCR 139

Query: 224 RRQP 227
            R+P
Sbjct: 140 SRRP 143


>gi|7706657 cell division cycle 40 homolog [Homo sapiens]
          Length = 579

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 92/469 (19%), Positives = 179/469 (38%), Gaps = 50/469 (10%)

Query: 41  VEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE 100
           VE ++ +  LT  + G  +T    +  + ++S  D     +     Y   DE  V   SE
Sbjct: 156 VEEAEKNQGLTVFETGQKKTEKRKKFKENDASNID---GFLGPWAKYV--DEKDVAKPSE 210

Query: 101 EEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRE 160
           EE++E +E   ++ ++  Q +    ++ +    + + D+       +P+           
Sbjct: 211 EEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQ----------- 259

Query: 161 RELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLH-FNQRGTWLASGSDDLKVVV 219
            ++G + R        + ++ + ++ H   GHT  V+ +  F   G  L S S D K+ +
Sbjct: 260 -DVGVNLRSTMPP--EKCYLPKKQI-HVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKL 315

Query: 220 WDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKN-TKR 278
           W+    +  L    GH   V    F  N+  +     A D  +++ +    QC    T R
Sbjct: 316 WEVYGERRCLRTFIGHSKAVRDICF--NTAGTQFLSAAYDRYLKLWDTETGQCISRFTNR 373

Query: 279 VAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIY 338
              +     K   + D    F++   D  +   D+R         + +E ++ +G     
Sbjct: 374 KVPY---CVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGE------IVQEYDRHLGAVNTI 424

Query: 339 VNPANTHQFAVGGRDQFVRIYD-QRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSH 397
           V      +F     D+ +R+++    +D                +   S  ++  +  S 
Sbjct: 425 VFVDENRRFVSTSDDKSLRVWEWDIPVD-------------FKYIAEPSMHSMPAVTLSP 471

Query: 398 DGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCG 457
           +G  L     D  I +F + +       K +KGH        V+F  P   +V+SG   G
Sbjct: 472 NGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDF-SPDMSYVISGDGNG 530

Query: 458 HIFLWE-KSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
            + +W+ K++    +F   DK  +     PH    V+ T G D  +K+W
Sbjct: 531 KLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVI-TCGWDGLIKLW 578


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 24/167 (14%)

Query: 25  EMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDT 84
           E  G  EG +     E+ A D  +   G++G      TES+    E+ GE K+ +   + 
Sbjct: 801 EGKGDNEGEDEG---EIHAEDGEMK--GNEG-----ETESQELSAENHGEAKNDEKGVED 850

Query: 85  GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSET 144
           G  S   ++   +  EEE+EEEEEEEE++     + +    +++  ++E    DW  +  
Sbjct: 851 GGGSDGGDSEEEEEEEEEQEEEEEEEEQEE----EEEEEEEEEEKGNEEPLSLDWPETRQ 906

Query: 145 S--------ALPRPRWQALPALRERELGSSARFVYEACGARVFVQRF 183
                     +  P W  +P +R +E  S   FV+   G+ +++  F
Sbjct: 907 KQAIYLFLLPIVFPLWLTVPDVRRQE--SRKFFVFTFLGSIMWIAMF 951


>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
          Length = 446

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 83/356 (23%), Positives = 140/356 (39%), Gaps = 37/356 (10%)

Query: 24  EEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTE-----SRGTDTESSGEDKDS 78
           EE+   EE        +  A  LS  +  D  G NRT          GT  ES+  ++  
Sbjct: 45  EELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNR-- 102

Query: 79  DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALED 138
             M    H     +    + S+EEEEEE+EE+EE+ + +++              R    
Sbjct: 103 -LMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMV---PHYGGINRVRVS 158

Query: 139 WVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQ----HGLEGHTG 194
           W+  E  A     W     +    L    + V E      F++  + Q        GH G
Sbjct: 159 WLGEEPVA---GVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMG 215

Query: 195 CVNTLHFNQRGTW-LASGSDDLKVVVW------DW-VRRQPVLDFESGHKSNVFQAKFLP 246
               L ++ R T  L +G     + +W       W V ++P +    GH  +V   ++ P
Sbjct: 216 EGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFV----GHTRSVEDLQWSP 271

Query: 247 NSGDSTLAMCARDGQVRVAELSA--TQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE 304
              ++  A C+ D  +R+ ++ A  ++ C  T   A H G  + ++     P   LS G+
Sbjct: 272 TE-NTVFASCSADASIRIWDIRAAPSKACMLTTATA-HDGDVNVISWSRREP-FLLSGGD 328

Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
           D  +   DLRQ +  S +   K+    V   ++  +P ++  FA  G D  +  +D
Sbjct: 329 DGALKIWDLRQFKSGSPVATFKQHVAPV--TSVEWHPQDSGVFAASGADHQITQWD 382



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 7/74 (9%)

Query: 446 KSEFVVSGSDCGHIFLWE----KSSCQIIQFMEGDKGGVVNCLEPHPH-LPVLATSGLDH 500
           +  F++SG D G + +W+    KS   +  F +      V  +E HP    V A SG DH
Sbjct: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQ--HVAPVTSVEWHPQDSGVFAASGADH 376

Query: 501 DVKIWAPTAEASTE 514
            +  W    E   E
Sbjct: 377 QITQWDLAVERDPE 390


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 70/285 (24%), Positives = 122/285 (42%), Gaps = 32/285 (11%)

Query: 192 HTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDS 251
           H G VN+  F+  G  L +GS+D  V  W+  R   +L    GH   V   +F P+    
Sbjct: 20  HGGEVNSSAFSPDGQMLLTGSEDGCVYGWE-TRSGQLLWRLGGHTGPVKFCRFSPDGHLF 78

Query: 252 TLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTI 311
             A C  D  VR+ +++  +C +  K    H+ +   ++  PDS     S G D  V   
Sbjct: 79  ASASC--DCTVRLWDVARAKCLRVLK---GHQRSVETVSFSPDSR-QLASGGWDKRVMLW 132

Query: 312 DLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNG 371
           D++  +    LV  ++  +              +  A G  D  V I+D R +    ++ 
Sbjct: 133 DVQSGQMLRLLVGHRDSIQSSDF------SPTVNCLATGSWDSTVHIWDLRMVTPAVSHQ 186

Query: 372 VLKKFCPHHLVNSESKANITCLVYSHDGTELLASYN-DEDIYLFNSSHSDGAQYVKRYKG 430
            L+             ANI+CL YS  G  LLAS + D+ I+++  + S     + + KG
Sbjct: 187 ALE----------GHSANISCLCYSASG--LLASGSWDKTIHIWKPTTS---SLLIQLKG 231

Query: 431 HRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEG 475
           H     VK + F  P   ++ S      + +W+ ++ + ++ ++G
Sbjct: 232 H--VTWVKSIAF-SPDELWLASAGYSRMVKVWDCNTGKCLETLKG 273



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 9/132 (6%)

Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
           L GHTG V    F+  G   AS S D  V +WD V R   L    GH+ +V    F P+S
Sbjct: 59  LGGHTGPVKFCRFSPDGHLFASASCDCTVRLWD-VARAKCLRVLKGHQRSVETVSFSPDS 117

Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGE-DAV 307
               LA    D +V + ++ + Q     + +  H+ +       P   C  L+ G  D+ 
Sbjct: 118 --RQLASGGWDKRVMLWDVQSGQM---LRLLVGHRDSIQSSDFSPTVNC--LATGSWDST 170

Query: 308 VFTIDLRQDRPA 319
           V   DLR   PA
Sbjct: 171 VHIWDLRMVTPA 182



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 29/95 (30%), Positives = 48/95 (50%), Gaps = 4/95 (4%)

Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232
           C  R++ V R +    L+GH   V T+ F+     LASG  D +V++WD V+   +L   
Sbjct: 85  CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWD-VQSGQMLRLL 143

Query: 233 SGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAEL 267
            GH+ ++  + F P    + LA  + D  V + +L
Sbjct: 144 VGHRDSIQSSDFSPTV--NCLATGSWDSTVHIWDL 176



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNC- 483
           V+R K    +      + + P  + +++GS+ G ++ WE  S Q++  + G  G V  C 
Sbjct: 11  VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCR 70

Query: 484 LEPHPHLPVLATSGLDHDVKIW 505
             P  HL   A++  D  V++W
Sbjct: 71  FSPDGHL--FASASCDCTVRLW 90


>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
          Length = 357

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 67/279 (24%), Positives = 118/279 (42%), Gaps = 32/279 (11%)

Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
           L+GH+G V  LH+N  G+ L S S D  V VWD    + V   + GH S V  + +    
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFV-NSCYPARR 162

Query: 249 GDSTLAMCARDGQVRVAEL---SATQCCKNTKRVAQHKGASHKLALE-PDSPCTFLSAGE 304
           G   +   + DG V++ ++   +A Q  +NT +V         LA+   D+    +S G 
Sbjct: 163 GPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV---------LAVTFNDTSDQIISGGI 213

Query: 305 DAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKI 364
           D  +   DLRQ++      +T          T     +          D  VR++D R  
Sbjct: 214 DNDIKVWDLRQNK------LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPF 267

Query: 365 DENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQY 424
              E      K    ++ N E   N+    +S DG+++ A   D  +Y+++++     + 
Sbjct: 268 APKER---CVKIFQGNVHNFEK--NLLRCSWSPDGSKIAAGSADRFVYVWDTT---SRRI 319

Query: 425 VKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWE 463
           + +  GH    ++  V F+ P    ++S S    +++ E
Sbjct: 320 LYKLPGHA--GSINEVAFH-PDEPIIISASSDKRLYMGE 355



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 63/313 (20%), Positives = 126/313 (40%), Gaps = 28/313 (8%)

Query: 189 LEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
           L GH G V    F+  G+ LAS   D  +++W+            GH   V +  +  N+
Sbjct: 62  LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHY--NT 119

Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308
             S L   + D  V V +    +  K  K       + +     P   CT     +D  V
Sbjct: 120 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCT---GSDDGTV 176

Query: 309 FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENE 368
              D+R      K    +  +    +  +  N   + Q   GG D  ++++D R   +N+
Sbjct: 177 KLWDIR------KKAAIQTFQNTYQVLAVTFND-TSDQIISGGIDNDIKVWDLR---QNK 226

Query: 369 NNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFN-SSHSDGAQYVKR 427
               ++              ++T L  S +G+ LL++  D  + +++    +   + VK 
Sbjct: 227 LTYTMRGHAD----------SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKI 276

Query: 428 YKGHRNNATVKGVN-FYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEP 486
           ++G+ +N     +   + P    + +GS    +++W+ +S +I+  + G  G  +N +  
Sbjct: 277 FQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAF 335

Query: 487 HPHLPVLATSGLD 499
           HP  P++ ++  D
Sbjct: 336 HPDEPIIISASSD 348



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 7/113 (6%)

Query: 393 LVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVS 452
           L Y+ DG+ L ++  D+ + +++S   +  + VKR KGH +          GP  + V +
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDS---ETGERVKRLKGHTSFVNSCYPARRGP--QLVCT 169

Query: 453 GSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
           GSD G + LW+      IQ  +      V  +  +     + + G+D+D+K+W
Sbjct: 170 GSDDGTVKLWDIRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVW 220



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)

Query: 184 RLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWD---WVRRQPVLDFESGHKSNVF 240
           +L + + GH   V  L  +  G++L S + D  V VWD   +  ++  +    G+  N F
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHN-F 284

Query: 241 QAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFL 300
           +   L  S     +  A     R   +  T   +   ++  H G+ +++A  PD P   +
Sbjct: 285 EKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEP-III 343

Query: 301 SAGED 305
           SA  D
Sbjct: 344 SASSD 348


>gi|8922301 WD repeat domain 70 [Homo sapiens]
          Length = 654

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 109/593 (18%), Positives = 207/593 (34%), Gaps = 108/593 (18%)

Query: 18  SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKD 77
           ++  S + +   E+  E +   E+   +  +  T       R  ++S   DT SS  ++ 
Sbjct: 50  AVERSRKTLEAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQS 109

Query: 78  SDSMEDT------------GHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
           SDS +D                +  +E+ +        EEEEE EEE+     +    ++
Sbjct: 110 SDSSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEEENPVHK 169

Query: 126 DQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRL 185
             DS +                                                     L
Sbjct: 170 IPDSHE---------------------------------------------------ITL 178

Query: 186 QHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLD-FESGHKSNVFQAKF 244
           +HG    T  V+ L  +  G  L +G  D  V  WD+         F S       Q K 
Sbjct: 179 KHG----TKTVSALGLDPSGARLVTGGYDYDVKFWDFAGMDASFKAFRSLQPCECHQIKS 234

Query: 245 LP--NSGDSTLAMCARDGQVRVAE---LSATQCCKNTKRVAQ------HKGASHKLALEP 293
           L   N+GD  L +     Q +V +       +C K  + +        H    H  +  P
Sbjct: 235 LQYSNTGDMILVVSG-SSQAKVIDRDGFEVMECIKGDQYIVDMANTKGHTAMLHTGSWHP 293

Query: 294 DSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRD 353
                F++   DA V T ++   +    +   +  + K  + T      + +  A   ++
Sbjct: 294 KIKGEFMTCSNDATVRTWEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQN 353

Query: 354 QFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYL 413
             ++I+D+       N  V  KF  H+    +S  + +C+ +S+DG  L +   D+ + L
Sbjct: 354 GSIQIWDR-------NLTVHPKF--HYKQAHDSGTDTSCVTFSYDGNVLASRGGDDSLKL 404

Query: 414 FNSSHSDGAQYVKRYKGHRNNATVKGVN--FYGPKSEFVVSGSD------CGHIFLWEKS 465
           +     D  Q+ K         T+  +    + P  + +V+G+        G +  +E+ 
Sbjct: 405 W-----DIRQFNKPLFSASGLPTMFPMTDCCFSPDDKLIVTGTSIQRGCGSGKLVFFERR 459

Query: 466 SCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLK-DVIKK 524
           + Q +  ++     VV CL  HP L  +     +   K++    + +    G K  V+K 
Sbjct: 460 TFQRVYEIDITDASVVRCLW-HPKLNQIMVGTGNGLAKVY---YDPNKSQRGAKLCVVKT 515

Query: 525 NKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESP 577
            ++ +  ++L Q  +   H L  +    RQR   ++  +  +    +   E P
Sbjct: 516 QRKAKQAETLTQDYIITPHAL-PMFREPRQRSTRKQLEKDRLDPLKSHKPEPP 567


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 15  ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73
           A+ S  SS EE++  E G +  +G          S + D+ G N T  E  G + +    
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212

Query: 74  EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132
           E+ + D+ ED       +E    +  EEEEEEEEEEE EQ  R   +K    D D+  +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%)

Query: 25  EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81
           E  G E  R  S   +    +++    G D   G    +  +   T+ E  G ++D +  
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212

Query: 82  EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135
           E+    +  DE    D  EEEEEEEEEEEEE+       Q +R  +++ +  D R+
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%)

Query: 59  RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110
           R S  S+ +  E + E+  SD       S ++ G+ + N+E  V +  EE+EE EE+ EE
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221

Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143
           +E+     + +    +++  ++E   E++   E
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 38/119 (31%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 15  ANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE-SSG 73
           A+ S  SS EE++  E G +  +G          S + D+ G N T  E  G + +    
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGS---------SGSSDEQG-NNTENEEEGVEEDVEED 212

Query: 74  EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDD 132
           E+ + D+ ED       +E    +  EEEEEEEEEEE EQ  R   +K    D D+  +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER--DQKEEGNDYDTRSE 269



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 5/116 (4%)

Query: 25  EMSGAEEGRETSSGIEVEASDLSLSLTGDD---GGPNRTSTESRGTDTESSGEDKDSDSM 81
           E  G E  R  S   +    +++    G D   G    +  +   T+ E  G ++D +  
Sbjct: 153 ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED 212

Query: 82  EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR--VQRKRANRDQDSSDDERA 135
           E+    +  DE    D  EEEEEEEEEEEEE+       Q +R  +++ +  D R+
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 24/93 (25%), Positives = 47/93 (50%), Gaps = 8/93 (8%)

Query: 59  RTSTESRGTDTESSGEDKDSD-------SMEDTGHYSINDENRVHDRSEEEEE-EEEEEE 110
           R S  S+ +  E + E+  SD       S ++ G+ + N+E  V +  EE+EE EE+ EE
Sbjct: 162 RASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEE 221

Query: 111 EEQPRRRVQRKRANRDQDSSDDERALEDWVSSE 143
           +E+     + +    +++  ++E   E++   E
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254


>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
          Length = 943

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
           GH   + TL ++Q G  LASGS D  ++VWD +    +   + GHK  + QA FL     
Sbjct: 105 GHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLK-GHKDAITQALFLREK-- 161

Query: 251 STLAMCARDGQVRVAELSATQCCK 274
           + L    +D  V+  +L    C K
Sbjct: 162 NLLVTSGKDTMVKWWDLDTQHCFK 185



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 68/325 (20%), Positives = 131/325 (40%), Gaps = 35/325 (10%)

Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
           GH   V TL F+     + S + D  + +W+    Q +      +    F   F+P  GD
Sbjct: 413 GHRSDVRTLSFSSDNIAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSF---FVP--GD 466

Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV-- 308
             + +  + G++++ +L++    +    +  H GA   ++L PD    F++ G D  V  
Sbjct: 467 RQVVIGTKTGKLQLYDLASGNLLET---IDAHDGALWSMSLSPDQR-GFVTGGADKSVKF 522

Query: 309 --FTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPA-NTHQFAVGGRDQFVRIYDQRKID 365
             F +   ++    +L V + +  ++    + V+ + N    AV   D  V+I+    +D
Sbjct: 523 WDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIF---YVD 579

Query: 366 ENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYV 425
                  LK F   +      K  + C+  SHDG  +     D ++ ++     D  + +
Sbjct: 580 ------TLKFFLSLY----GHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSL 629

Query: 426 KRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLE 485
                  ++ +V  + F  PKS    +      I  W+    + IQ +EG    +  CL 
Sbjct: 630 -----FAHDDSVMYLQFV-PKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIW-CLA 682

Query: 486 PHPHLPVLATSGLDHDVKIWAPTAE 510
             P    + +S  D  +++W  T E
Sbjct: 683 VSPSGDYVVSSSHDKSLRLWERTRE 707



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 7/119 (5%)

Query: 387 KANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPK 446
           K  +TCL  S DG  L   Y D  I +F+    +G      + GH+   T    +  G +
Sbjct: 65  KQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGN---VTFNGHKAAITTLKYDQLGGR 121

Query: 447 SEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW 505
              + SGS    I +W+  +   +  ++G K  +   L       +L TSG D  VK W
Sbjct: 122 ---LASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLR-EKNLLVTSGKDTMVKWW 176



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 440 VNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLD 499
           V   G K  +V   + C H+F+W+    + I  ++G K   V CL P P    LA    D
Sbjct: 29  VTLRGEKGRYVAVPA-CEHVFIWDLRKGEKILILQGLK-QEVTCLCPSPDGLHLAVGYED 86

Query: 500 HDVKIWA-PTAEASTELTGLKDVIKKNKRER 529
             ++I++  + E +    G K  I   K ++
Sbjct: 87  GSIRIFSLLSGEGNVTFNGHKAAITTLKYDQ 117



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 14/82 (17%)

Query: 174 CGARVF-VQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFE 232
           C  ++F V   +    L GH   V  +  +  G  +A+GS D  V +W        LDF 
Sbjct: 571 CTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWG-------LDFG 623

Query: 233 SGHKS------NVFQAKFLPNS 248
             HKS      +V   +F+P S
Sbjct: 624 DCHKSLFAHDDSVMYLQFVPKS 645


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 4/144 (2%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +   +D +N S SS   + S + E  ++S   + ++SD S S   +    +  S
Sbjct: 671 SSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN----SSDS 726

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
             S  +D+  S    DS    D+ + S + ++     S +  +  +  +           
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786

Query: 122 RANRDQDSSDDERALEDWVSSETS 145
            ++   DSSD   + +   SS++S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSS 810



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 28/140 (20%), Positives = 62/140 (44%), Gaps = 5/140 (3%)

Query: 6   SSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESR 65
           S++D     +NG+ ++  ++   ++ G+  S   + ++SD S S    D   + +S  + 
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576

Query: 66  GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
            +D++SS  D    S  D+     +D +   D S+  +  +  +  +    +    ++  
Sbjct: 577 SSDSDSSDSDSSDSSDSDS-----SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 126 DQDSSDDERALEDWVSSETS 145
           D   SD +    D  SS++S
Sbjct: 632 DSSDSDSKSDSSDSNSSDSS 651



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 1/144 (0%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +   +D ++ S SS  +  + ++    + S     +SD S S    DG  + +S
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
             S  +++  S +  DS +  D+   S ++E+     S +     + +  +         
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 122 RANRDQDSSDDERALEDWVSSETS 145
            +N   DSS+   + ++  SS++S
Sbjct: 917 SSN-SSDSSESSNSSDNSNSSDSS 939



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 2/146 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D +N S SS   + S + +   +S S    E+SD S S    D   +  
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167

Query: 61   STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S++S   +D+ +S +  DS    D+   S + ++     S +  +  +  +         
Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227

Query: 120  RKRANRDQDSSDDERALEDWVSSETS 145
               +N   DSSD   + +   SS++S
Sbjct: 1228 SSDSNESSDSSDSSDSSDSSNSSDSS 1253



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/145 (24%), Positives = 64/145 (44%), Gaps = 3/145 (2%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
           SS  S++   +D ++ S SSS  + S + +  ++S S    E+SD S S +  D   +  
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS-SDSDSSDSSD 717

Query: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           S+ S  +D++SS     SDS   +     +D +   D S+  +     +  +        
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
             +N   DS+D   + +   SS +S
Sbjct: 778 DSSN-SSDSNDSSNSSDSSDSSNSS 801



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D +N S SS+  + S + +  ++S S    ++SD S S    D   +  
Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            S++S  +D+  S +  +S    D+ + S + ++     S +  +  +  +          
Sbjct: 1069 SSDS--SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SSE+S
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESS 1151



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 6/149 (4%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           S    S+D  +  +N S S S    S + +  ++ S     +SD S S    D   +  S
Sbjct: 561 SDSSDSSDSDSSDSNSS-SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE-----EEEEEEEEEEEEQPRR 116
           ++S+   ++S  +  DSDS  D+   + +D +   D S+        +  +  +      
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145
                 ++   DSSD   + E   SS++S
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSS 708



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 5/149 (3%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S ++  ++ ++ S SS+  + S + +  ++S   + ++S+ S S    D   +  S
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYS----INDENRVHDRSEEEEEEEEEEEEEQPRRR 117
           ++S  +   S G D DS +  D+ + S     +D +   D S+  +  E     +     
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898

Query: 118 VQRKRANRDQ-DSSDDERALEDWVSSETS 145
                 + D  +SSD   +     SSE+S
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESS 927



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/144 (21%), Positives = 57/144 (39%), Gaps = 2/144 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S     +D +N S SS   + S + +   +S      +SD S S + D    + +S
Sbjct: 926  SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN--SSDSSDSNSSDSSDSSNSS 983

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
              S  +D+  S +  DS +  D+   S + ++     S    +     +           
Sbjct: 984  DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSS 1067



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/144 (22%), Positives = 62/144 (43%), Gaps = 2/144 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D +N S SS+  + S +     + S    ++SD S S    D   +  S
Sbjct: 944  SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
            ++S  + ++SS     SDS   +   + +D +   D S+  +  +  +  +         
Sbjct: 1004 SDSSDS-SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSS 1061

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SSE+S
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESS 1085



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 9/130 (6%)

Query: 3   SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
           S  S +   +D ++ S SS   + S + + +  SS  E ++SD        D   + +S 
Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652

Query: 63  ESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
            S  +D+ +S    DS DS + +   S +D +   D S+  +     E  +         
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD------ 706

Query: 122 RANRDQDSSD 131
             + D DSSD
Sbjct: 707 --SSDSDSSD 714



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 33/145 (22%), Positives = 60/145 (41%), Gaps = 14/145 (9%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60
           SS  S +   +D ++ S SS   + S + +  ++S+  +   +SD S S    D   + +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           S  S  +D+  S    DS    D+   S +D +   D S   +  +  +           
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD----------- 872

Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + E   SS++S
Sbjct: 873 --SSNSSDSSDSSDSNESSNSSDSS 895



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 33/148 (22%), Positives = 62/148 (41%), Gaps = 6/148 (4%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57
            SS  S +   +D +N S SS   + S + +  ++S    S    ++SD S S    D   
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101

Query: 58   NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
            +  S++S  +D+  S +  DS +  D+   S + ++     S +  +  E  +       
Sbjct: 1102 SSDSSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159

Query: 118  VQRKRANRDQDSSDDERALEDWVSSETS 145
                 ++   DSSD   +     SS++S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 32/141 (22%), Positives = 57/141 (40%), Gaps = 6/141 (4%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS----SGIEVEASDLSLSLTGDDGGP 57
            SS  S +   +D +N S SS   E S + +  ++S    S    ++SD S S    D   
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185

Query: 58   NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
            +  S++S  +D+  S +  DS    D+   S + ++     S +  +  E  +       
Sbjct: 1186 SSDSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243

Query: 118  VQRKRANRDQDSSDDERALED 138
                 ++   DSSD   +  D
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSD 1264



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 7/140 (5%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D +N S SS   + S + +  ++S   +  +SD S S    D   +  S
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDS 1222

Query: 62   TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            ++S  +D+  S E  D SDS + +   + +D +   D S+   +  +E + +        
Sbjct: 1223 SDS--SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280

Query: 121  KRANRDQDS--SDDERALED 138
              ++ D DS  SD   +  D
Sbjct: 1281 NGSDSDSDSEGSDSNHSTSD 1300



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 29/144 (20%), Positives = 59/144 (40%), Gaps = 1/144 (0%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           S KG S    +D ++ S SS   + S ++     SS  + ++SD   S + D    + ++
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS-DSDSSDSDSSDSSDSDSSDSSN 600

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
           +      ++SS     SDS +     S ++ +     S+ +  +    +           
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660

Query: 122 RANRDQDSSDDERALEDWVSSETS 145
            ++   DSSD   + +   SS++S
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSS 684



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 4/146 (2%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +   +D ++ S SS   + S + +G ++ S    ++S+ S S    D   +  S
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
           ++S  ++ ESS     SDS   +   S +D +   D S+     +  E            
Sbjct: 880 SDSSDSN-ESSNSSDSSDSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937

Query: 122 RANR--DQDSSDDERALEDWVSSETS 145
            +N     DSSD   + +   SS++S
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSS 963



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 32/144 (22%), Positives = 63/144 (43%), Gaps = 8/144 (5%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  +S+D  +D +N S SS   + S + +  ++S+     +SD S S   D    + +S
Sbjct: 968  SSDSNSSDS-SDSSNSSDSSDSSDSSDSSDSSDSSN-----SSDSSDS--SDSSDSSNSS 1019

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
              S  +D+ +S +  DS    D+   S + ++     S +  +  +  +           
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSS 1103



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/145 (21%), Positives = 61/145 (42%), Gaps = 6/145 (4%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D +N S SS+  + S + +  ++S     ++SD S S    D   +  S
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS-----DSSDSSDSSDSSDSSDSSNS 1057

Query: 62   TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            ++S   +D+  S +  DS    D+   S + ++     S +  +  +  +          
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS +S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSS 1142



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 12/148 (8%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +   +D +N S SS   + S ++    + S    ++SD S S    D   +   
Sbjct: 791 SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850

Query: 62  TES----RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
           ++S    R   + SS     SDS   +     +D N   + S+  +     + +      
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSD--- 907

Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145
                ++   DSSD   + +   SS +S
Sbjct: 908 -----SSNSSDSSDSSNSSDSSESSNSS 930



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/146 (21%), Positives = 62/146 (42%), Gaps = 2/146 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   + S + E  ++S S    ++SD S S    D   +  
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1113

Query: 61   STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S++S  +   S S +  DS    D+ + S + ++     S +  +  +  +         
Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173

Query: 120  RKRANRDQDSSDDERALEDWVSSETS 145
               ++   DSSD   + +   SS++S
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSS 1199



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS+  + S + +  ++S S    ++SD S S    D   +  
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            S++S  +D+  S +  DS +  D+   S + ++     S +  +  +  +          
Sbjct: 1162 SSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1220 SDSSDSSDSSDSNESSDSSDSSDSS 1244



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 4/144 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS+  + S + E  ++S   +  +SD S S   D    + +S
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD--SSDSSDS--SDSSDSSDSS 1175

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
              S  +D+  S +  DS    D+   S + ++     S +  +  +  +        +  
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSS 1259



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%)

Query: 3   SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
           S  S +D ++D ++ + S S +    ++    ++S    ++SD S S +  D   +  S+
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690

Query: 63  ESRGTD--TESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           +S  +   +ESS     SDS       S N  +   D S   +  +     +        
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS-DS 749

Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 750 SNSSDSSDSSDSSNSSDSSDSSDSS 774



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 27/136 (19%), Positives = 54/136 (39%), Gaps = 6/136 (4%)

Query: 2   SSKGSSTDGRTDLANGS------LSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDG 55
           SS  S +   +D ++GS       S S      ++    ++S    ++SD + S    D 
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894

Query: 56  GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115
             +  S++S  +D+ +S +  DS +  D+   S + +N     S    +  +  +     
Sbjct: 895 SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954

Query: 116 RRVQRKRANRDQDSSD 131
                  ++   DSSD
Sbjct: 955 DSSNSSDSSNSSDSSD 970



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 31/147 (21%), Positives = 64/147 (43%), Gaps = 2/147 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   + S + +  ++S S    ++SD S S    D   +  
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212

Query: 61   STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S++S   +D+  S +  DS+   D+   S + ++     S +  +  +   +       Q
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272

Query: 120  RKRANRDQDSSDDERALEDWVSSETSA 146
             K  N + + SD +   E   S+ +++
Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 14/144 (9%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D +N S SS+  + S + +   +S      +SD S S    D   + +S
Sbjct: 920  SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN--SSDSSNSSDSSDSNSSDSS 977

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
              S  +D+  S +  DS    D+ + S  D +   D S+     +     +         
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSS--DSSDSSDSSDSSNSSDSSNSSD--------- 1026

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1027 -SSNSSDSSDSSDSSDSSDSSDSS 1049



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS   + S + +  ++S   +  +SD S S    D   +  S
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSESSDS 1087

Query: 62   TE-SRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            ++ S  +D+  S +  DS    D+   S + ++     S +  +  +  +          
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSS 1172



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 4/144 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS   + S + +  ++S   +  +SD S S    D   +  S
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSNS 1123

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
            ++S  +D+  S +  DS +  D+   S + ++     S +  +  +  +           
Sbjct: 1124 SDS--SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSS 1205



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/144 (21%), Positives = 61/144 (42%), Gaps = 7/144 (4%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D +N S SS   + S + +  ++S     ++SD S S    D   +  S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS-----DSSDSSDSSNSSDSSDSSDS 1132

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
            ++S  +D+ +S +  DS    D+   S + ++     S +  +  +              
Sbjct: 1133 SDS--SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSS 1214



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/145 (20%), Positives = 62/145 (42%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS   + S + +  ++S   +  +SD S S    D   +  S
Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSNSSDSSDSSESSDS 1153

Query: 62   TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            ++S   +D+  S +  DS    D+ + S + ++     S +  +  +  +          
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSS 1238



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/146 (21%), Positives = 61/146 (41%), Gaps = 4/146 (2%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +   +D +N S SS   + S + +  ++S   +   S  S S + D    + +S
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSNDSSNSSDSS 795

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
             S  +D+ +S +  DS    D+   + +D +   D S+     +  +  +         
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS-DSD 854

Query: 122 RANRDQD--SSDDERALEDWVSSETS 145
            +NR     SSD   + +   SS++S
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSS 880



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 8/145 (5%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
           SS  S +   +D +N S SS   + S + +   +S S     +SD S S    D   +  
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808

Query: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           S++S  +    S    DS +  D+     +D +   D S+  +  +  + +     R   
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDS-----SDSSNSSDSSDSSDSSDGSDSDSS--NRSDS 861

Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS+++
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSN 886



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 27/144 (18%), Positives = 55/144 (38%), Gaps = 2/144 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            S+   S+D      +   S S +    ++    + S    ++SD S S   D    + +S
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS--SDSSNSSDSS 1028

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
              S  +D+  S +  DS    D+   S + ++     S +  +  +  +           
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088

Query: 122  RANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS++S
Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSS 1112



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S++   +D ++ S SS   + S + +   +S S    ++SD S S    D   +  
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083

Query: 61   STESRGTDTES-SGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S++S  +   S S +  DS    D+   S + ++     S +  +  +  +         
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 120  RKRANRDQDSSDDERALEDWVSSETS 145
               ++   DSSD   + +   SS++S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSS 1169



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVE-ASDLSLSLTGDDGGPNRT 60
            SS  S +   +D +N S SS   + S +    ++S+  +   +SD S S    D   +  
Sbjct: 988  SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            S++S  +D+ +S +  DS    D+   S + ++     S +  +     +          
Sbjct: 1048 SSDS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   +     SS++S
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSS 1130



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 30/145 (20%), Positives = 61/145 (42%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS+  + S + +  ++S   +  +SD S S    D   +  S
Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSDSSDSSNS 1093

Query: 62   TESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            ++S   +D+  S +  DS    D+   S + ++     S +  +     +          
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSS 1178



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 32/145 (22%), Positives = 60/145 (41%), Gaps = 3/145 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   E S + +   +S S    ++SD S S   D    + +
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS--SDSSDSSDS 1117

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            S  S  +D+  S +  DS    ++   S + E+     S +  +  +  +          
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSS 1202



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 2/146 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   + S + +   +S S    ++SD S S    D   +  
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149

Query: 61   STESR-GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S++S   +D+  S +  DS    D+   S + ++     S +  +  +  +         
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209

Query: 120  RKRANRDQDSSDDERALEDWVSSETS 145
               ++   DSSD   + +   S+E+S
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESS 1235



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 9/153 (5%)

Query: 2    SSKGSSTD--GRTDLANGSLSSSPEEMSGAEEGRETS-------SGIEVEASDLSLSLTG 52
            SS   S+D    +D ++ S SS   E S + +   +S       S    ++S+ S S   
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959

Query: 53   DDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEE 112
             D   +  S++S  +D+  S    DS    D+   S + ++     S +  +  +     
Sbjct: 960  SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019

Query: 113  QPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
                      ++   DSSD   + +   SS++S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/145 (22%), Positives = 59/145 (40%), Gaps = 9/145 (6%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
           SS  S     +D +N S SS   + S + +   +S S    ++SD S S    +   +  
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706

Query: 61  STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
           S++S  +D+  S     SDS + +     +D +   D S+  +     +  +        
Sbjct: 707 SSDSDSSDSSDSSNSNSSDS-DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS------- 758

Query: 121 KRANRDQDSSDDERALEDWVSSETS 145
             ++   DSSD   + +   SS +S
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSS 783



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 33/158 (20%), Positives = 65/158 (41%), Gaps = 15/158 (9%)

Query: 3   SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSL----------T 51
           S  S++   +D +N S SS   + S + +  ++S S    ++SD S S           +
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 52  GDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSE----EEEEEEE 107
            D    + +S  S  +D+ +S +  DS    D+   + +D +   D S+     +  +  
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 108 EEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETS 145
           +  +        R  ++   DSSD   +     SS++S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 31/145 (21%), Positives = 66/145 (45%), Gaps = 6/145 (4%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60
            SS  S++   +D ++ S SS   + S + +  ++S+  +  ++SD S S    +   +  
Sbjct: 1087 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            S+ES  + ++SS     SDS + +     +D +   D S+  +  +  +  +        
Sbjct: 1147 SSESSDS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS----DS 1201

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSS 1226



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 3/132 (2%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   +D ++ S SS   + S + +  ++S+  +  +SD S S    D   +  S
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSDSSDS 1201

Query: 62   TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
            ++S  + ++SS     SDS + +     +D N   D S+  +  +     +         
Sbjct: 1202 SDSSDS-SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260

Query: 122  RANRDQDSSDDE 133
              +   D SD +
Sbjct: 1261 STSDSNDESDSQ 1272



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 31/144 (21%), Positives = 60/144 (41%), Gaps = 10/144 (6%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S++    D +N S SS     S +    ++S     ++SD S S + +    + +S
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS-----DSSDSSDSDSSNSSDSSNSS 830

Query: 62  TESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRK 121
             S  +++  S +  DS    D+   + +D +   D S+  +     +  +         
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS----DSN 886

Query: 122 RANRDQDSSDDERALEDWVSSETS 145
            ++   DSSD   +  D  SS++S
Sbjct: 887 ESSNSSDSSDSSNS-SDSDSSDSS 909



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETS-SGIEVEASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   E S + +  ++S S    ++SD S S        + +
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDE 92
             ++S+  +  ++G D DSDS     ++S +D+
Sbjct: 1270 DSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 8/145 (5%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
            SS  S +   ++ ++ S SS   E S + +  ++S+  + ++SD S S    D   +  S
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923

Query: 62   TESRGTDTESSGEDKD-SDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQR 120
            +ES      +S ++ + SDS   +     +D +   D S   +     +  +        
Sbjct: 924  SES-----SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS--NSSDS 976

Query: 121  KRANRDQDSSDDERALEDWVSSETS 145
              ++   DSSD   + +   SS++S
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSS 1001



 Score = 37.0 bits (84), Expect = 0.052
 Identities = 30/149 (20%), Positives = 61/149 (40%), Gaps = 9/149 (6%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTS 61
           SS  S +D      + + +SS  + S + +  ++S+  +  +SD S S    D   +  S
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDS 761

Query: 62  TESRGT-----DTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRR 116
           + S  +      ++SS     SDS + +     +D +   D S   +  +  +  +    
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821

Query: 117 RVQRKRANRDQDSSDDERALEDWVSSETS 145
                 ++   DSSD   + +   SS++S
Sbjct: 822 --NSSDSSNSSDSSDSSNSSDSSDSSDSS 848



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 31/157 (19%), Positives = 58/157 (36%), Gaps = 12/157 (7%)

Query: 2   SSKGSSTDGRTDLANGSLSSSPEEMSGAEEG----------RETSSGIEVEASDLSLSLT 51
           SS  S +   +D +N S SS   + S ++             ++ S    ++SD S S  
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742

Query: 52  GDDGGPNRTSTESRGTDTESSGED--KDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEE 109
             D   +  S++S  +   S+  D    SDS + +   + +D N   + S+  +     +
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802

Query: 110 EEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSA 146
                        ++ D  +S D     D   S  S+
Sbjct: 803 SSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 24/110 (21%), Positives = 49/110 (44%), Gaps = 1/110 (0%)

Query: 2    SSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLSLSLTGDDGGPNRT 60
            SS  S +   +D ++ S SS   + S + +  ++S   +  E+SD S S    D   +  
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251

Query: 61   STESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEE 110
            S++S  +   +S  + +SDS   +G+ + N  +   D    +      ++
Sbjct: 1252 SSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/154 (20%), Positives = 63/154 (40%), Gaps = 10/154 (6%)

Query: 3    SKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEV-EASDLS-LSLTGDDGGPNRT 60
            S  S++   +D +N S SS   + S + +  ++S+  +  ++SD S  S + D    + +
Sbjct: 968  SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027

Query: 61   STESRGTDTESSGEDKDS-DSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQ 119
            S  S  +D+  S +  DS DS + +   + +D +   D S+  +  +  +  +       
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 120  RKRANR-------DQDSSDDERALEDWVSSETSA 146
               +N        D   S D     D   S  S+
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 34/151 (22%), Positives = 62/151 (41%), Gaps = 9/151 (5%)

Query: 5   GSSTDGRTDLANG--SLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTST 62
           G S  G    ++G  S     + M G +      S    +A+  S + +   G  +  S 
Sbjct: 437 GHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496

Query: 63  ESR--GTDTESSG-EDKDSDSMEDTGHYSI----NDENRVHDRSEEEEEEEEEEEEEQPR 115
           ES+  G  ++S G ED DSDS  DT +       N+ N  +D+S+  + + +  + +   
Sbjct: 497 ESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556

Query: 116 RRVQRKRANRDQDSSDDERALEDWVSSETSA 146
                  ++     S D  +  D  SS++ +
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 31/148 (20%), Positives = 62/148 (41%), Gaps = 26/148 (17%)

Query: 2   SSKGSST---DGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPN 58
           SS+G ++   D   D  NGS      +  GAE+    S+    + ++   +  G++G  +
Sbjct: 486 SSRGDASYNSDESKDNGNGS------DSKGAEDDDSDSTS---DTNNSDSNGNGNNGNDD 536

Query: 59  RTSTES-RGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
              ++S +G    S  +  DS +  D+   S +D +  +  S+ +  + +  +       
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS----- 591

Query: 118 VQRKRANRDQDSSDDERALEDWVSSETS 145
                   D DSSD   + +   SS++S
Sbjct: 592 --------DSDSSDSSNSSDSSDSSDSS 611



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 23/146 (15%), Positives = 57/146 (39%), Gaps = 18/146 (12%)

Query: 1   MSSKGSSTDGRTDLAN------GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDD 54
           ++   +STD   ++        G+ S    +++    G + +        D  L     D
Sbjct: 186 VAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLD--NSD 243

Query: 55  GGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEE----------E 104
           G P+    +    +     ED+++ + +D+ + S   E + H + ++ +          E
Sbjct: 244 GSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKE 303

Query: 105 EEEEEEEEQPRRRVQRKRANRDQDSS 130
             + E +E P   V   + ++ +++S
Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENS 329



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 28/146 (19%), Positives = 56/146 (38%), Gaps = 19/146 (13%)

Query: 17  GSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDK 76
           G   +S +E +G ++    S        D S +   D+   N   ++S+G + + S    
Sbjct: 462 GDDPNSSDESNGNDDANSESDNNSSSRGDASYN--SDESKDNGNGSDSKGAEDDDSDSTS 519

Query: 77  DSDSMEDTGHYSI-NDENRVHDR--------------SEEEEEEEEEEEEEQPRRRVQRK 121
           D+++ +  G+ +  ND+N   D               S    +  +  + +         
Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD 579

Query: 122 RANRDQDSSD--DERALEDWVSSETS 145
             + D DSSD  D  + +   SS++S
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSS 605


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 11/173 (6%)

Query: 1   MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRT 60
           MSS  S   G      G +  + ++   A+ GR+     + + SD       DDG     
Sbjct: 216 MSSDASDASGEE---GGRVPKAKKKAPLAKGGRKKK---KKKGSDDEAFEDSDDGDFEGQ 269

Query: 61  STESRGTDTESSGEDKDSDS---MEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
             +     + SS E+ +S +    ++ G   +++++   + SEEE+  EE++EEE+ ++ 
Sbjct: 270 EVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKA 329

Query: 118 VQRKRANRDQDSSDDERALE--DWVSSETSALPRPRWQALPALRERELGSSAR 168
              +   R +DSS++  + E  D  S  +SAL   + +  P    +  G S+R
Sbjct: 330 PTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSR 382



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 3/97 (3%)

Query: 58  NRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRR 117
           N T      T T    E++     +   H+SI  + R+ D+ ++E   +EEE+E++ RR+
Sbjct: 145 NFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDE---DEEEKEKRGRRK 201

Query: 118 VQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQA 154
               R +  +D  +      D    E   +P+ + +A
Sbjct: 202 ASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKA 238


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 16/110 (14%)

Query: 22  SPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSM 81
           S  E+ G +E  E   G + E  D       D+ G      E    D +  G++ D +  
Sbjct: 158 SDAEVDGVDEEEEDEEGEDEEDED-------DEDGEEEEFDEEDDEDEDVEGDEDDDEVS 210

Query: 82  EDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSD 131
           E+   + ++         EE+E+E+E+EEEE+  +  +RKR   D+   D
Sbjct: 211 EEEEEFGLD---------EEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 56  GPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPR 115
           G +R   E+  +D E  G D++ +  E       +DE+   +  +EE++E+E+ E ++  
Sbjct: 147 GYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD 206

Query: 116 RRVQRKRA-----NRDQDSSDDERALE 137
             V  +         D+D  +DE   E
Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEE 233



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 6/73 (8%)

Query: 66  GTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANR 125
           G D E   E  DSD+  D       DE    +  E+EE+E++E+ EE+       +  + 
Sbjct: 147 GYDREDQ-EAPDSDAEVDGV-----DEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200

Query: 126 DQDSSDDERALED 138
           + D  DDE + E+
Sbjct: 201 EGDEDDDEVSEEE 213


>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
          Length = 501

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 6/130 (4%)

Query: 190 EGHTGCVNTLHFNQR-GTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNS 248
           EGHT  V  L +N+     LAS S D  V++WD    +P     + H   V   +F P  
Sbjct: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311

Query: 249 GDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVV 308
              TL   + D  V + +  +      + R+ +  G   ++     SPC FL++ +D  V
Sbjct: 312 AQ-TLISGSYDKSVALYDCRSPD---ESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFV 367

Query: 309 FTIDLRQDRP 318
           + +D R D+P
Sbjct: 368 YNLDARSDKP 377



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 42/216 (19%)

Query: 301 SAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYD 360
           SA  D  V   D+   +PA+ L V  +K     + T+  +P        G  D+ V +YD
Sbjct: 274 SASADNTVILWDMSLGKPAASLAVHTDK-----VQTLQFHPFEAQTLISGSYDKSVALYD 328

Query: 361 QRKIDENEN----NGVLKK-----FCPHHLVNSESKANITCLVYSHDGTELLASYNDEDI 411
            R  DE+      +G +++     F P H + S         VY+ D      + +D+ I
Sbjct: 329 CRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG----FVYNLD------ARSDKPI 378

Query: 412 YLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQ 471
           +  N+                +N  + G++        +V+ S   ++ +W+    +   
Sbjct: 379 FTLNA----------------HNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSL 422

Query: 472 FMEGD-KGGVVNCLEPHPHLP-VLATSGLDHDVKIW 505
               D K GV+ C    P LP + A  G    +++W
Sbjct: 423 VHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVW 458


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 13/104 (12%)

Query: 41  VEASDLSLSL--TGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDR 98
           VE SD++      G  GGPN T T    T  +S GE+++ +  E+       +E      
Sbjct: 375 VEPSDIAACFREAGFGGGPNATIT----TSLKSEGEEEEEEEEEE-------EEEEGEGE 423

Query: 99  SEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSS 142
            EEEE EEEEEE  +     + +    + D   DE   ED  SS
Sbjct: 424 EEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 15/101 (14%)

Query: 17  GSLSSSPEEMSGAEEGRETSS-GIEVEASDLSLSLTGDDGGPNRTSTESRGTDTE--SSG 73
           G + S  EE    EE  E+SS G+E E     +   G   G      E++         G
Sbjct: 452 GDVDSDEEE----EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507

Query: 74  EDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQP 114
           ED DSDS E+        ++   D  +E+++++EE+ +E P
Sbjct: 508 EDSDSDSEEE--------DDEEEDDEDEDDDDDEEDGDEVP 540


>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
          Length = 1495

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 21/136 (15%)

Query: 54  DGGPNRTSTESRGTDTESSGEDKDSDSMEDT-------GHYSINDENRVHDR---SEEEE 103
           +G  N T+ E  G  T  +  D D +S E T        H++ + + +  +     EEEE
Sbjct: 790 EGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEMIPSDEEEE 849

Query: 104 EEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALREREL 163
           ++EEEEEEE+PR  +  +R + D  +++DE       S +  AL            + EL
Sbjct: 850 DDEEEEEEEEPRLTI-NQREDEDGMANEDELDNTYTGSGDEDALSE---------EDDEL 899

Query: 164 GSSARFV-YEACGARV 178
           G +A++   + CG  V
Sbjct: 900 GEAAKYEDVKECGKHV 915


>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
          Length = 589

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 3/82 (3%)

Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
           GH G V +L F+  G +LAS  +D ++ +WD        +   GH  N+    F P+SG 
Sbjct: 466 GHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELR-GHTDNITSLTFSPDSG- 523

Query: 251 STLAMCARDGQVRVAELSATQC 272
             +A  + D  VRV ++  T C
Sbjct: 524 -LIASASMDNSVRVWDIRNTYC 544



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 13/173 (7%)

Query: 190 EGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSG 249
           +GH   V  L  +    + ASGS D    +W + R  P L   +GH ++V   KF PNS 
Sbjct: 381 QGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP-LRIYAGHLADVDCVKFHPNS- 438

Query: 250 DSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVF 309
            + LA  + D  VR   L + Q   + +    H+G    LA  P+      SAGED  + 
Sbjct: 439 -NYLATGSTDKTVR---LWSAQQGNSVRLFTGHRGPVLSLAFSPNGK-YLASAGEDQRLK 493

Query: 310 TIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQR 362
             DL          + KE        T      ++   A    D  VR++D R
Sbjct: 494 LWDLASG------TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 41/157 (26%), Positives = 66/157 (42%), Gaps = 9/157 (5%)

Query: 191 GHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGD 250
           GH   V+ + F+    +LA+GS D  V +W   +   V  F +GH+  V    F PN   
Sbjct: 424 GHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF-TGHRGPVLSLAFSPNG-- 480

Query: 251 STLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFT 310
             LA    D ++++ +L++    K  +    H      L   PDS     SA  D  V  
Sbjct: 481 KYLASAGEDQRLKLWDLASGTLYKELR---GHTDNITSLTFSPDSG-LIASASMDNSVRV 536

Query: 311 IDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQF 347
            D+R    ++         + VG+YT  ++   + QF
Sbjct: 537 WDIRNTYCSAP--ADGSSSELVGVYTGQMSNVLSVQF 571



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 18/152 (11%)

Query: 396 SHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSD 455
           SHD T  L S+             D    ++ Y GH   A V  V F+ P S ++ +GS 
Sbjct: 403 SHDRTARLWSF-------------DRTYPLRIYAGHL--ADVDCVKFH-PNSNYLATGST 446

Query: 456 CGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIW-APTAEASTE 514
              + LW       ++   G +G V++ L   P+   LA++G D  +K+W   +     E
Sbjct: 447 DKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 505

Query: 515 LTGLKDVIKKNKRERDEDSLHQTDLFDSHMLW 546
           L G  D I       D   +    + +S  +W
Sbjct: 506 LRGHTDNITSLTFSPDSGLIASASMDNSVRVW 537



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 1/71 (1%)

Query: 445 PKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKI 504
           P S +  SGS      LW       ++   G    V +C++ HP+   LAT   D  V++
Sbjct: 394 PYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADV-DCVKFHPNSNYLATGSTDKTVRL 452

Query: 505 WAPTAEASTEL 515
           W+     S  L
Sbjct: 453 WSAQQGNSVRL 463


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,171,101
Number of Sequences: 37866
Number of extensions: 1254478
Number of successful extensions: 27620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 636
Number of HSP's successfully gapped in prelim test: 460
Number of HSP's that attempted gapping in prelim test: 11601
Number of HSP's gapped (non-prelim): 8276
length of query: 597
length of database: 18,247,518
effective HSP length: 108
effective length of query: 489
effective length of database: 14,157,990
effective search space: 6923257110
effective search space used: 6923257110
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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