Search of human proteins with 30061556

Search of human proteins with 30061556

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
         (446 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]       896   0.0  
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       391   e-109
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]             342   4e-94
gi|5902108 SRY-box 21 [Homo sapiens]                                  181   2e-45
gi|4759162 SRY-box 14 [Homo sapiens]                                  165   7e-41
gi|5902106 SRY-box 15 [Homo sapiens]                                  146   4e-35
gi|4507225 sex determining region Y [Homo sapiens]                    139   5e-33
gi|11967991 SRY-box 17 [Homo sapiens]                                 133   4e-31
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        128   1e-29
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      126   5e-29
gi|8924248 SRY-box 18 [Homo sapiens]                                  124   2e-28
gi|4507161 SRY-box 11 [Homo sapiens]                                  123   3e-28
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]       120   2e-27
gi|13899269 SRY-box 7 [Homo sapiens]                                  119   6e-27
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]       115   1e-25
gi|4557853 transcription factor SOX9 [Homo sapiens]                   110   2e-24
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   104   1e-22
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   104   1e-22
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   104   1e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...    99   8e-21
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...    99   1e-20
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...    99   1e-20
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...    99   1e-20
gi|41406089 SRY-box 13 [Homo sapiens]                                  98   1e-20
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    84   3e-16
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    84   3e-16
gi|112421108 capicua homolog [Homo sapiens]                            82   1e-15
gi|122937319 even-skipped homeobox 2 [Homo sapiens]                    69   9e-12
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]    63   5e-10
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]    63   6e-10

>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score =  896 bits (2316), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 1   MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGA 60
           MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGA
Sbjct: 1   MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGLFTVAAPAPGA 60

Query: 61  PSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSG 120
           PSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSG
Sbjct: 61  PSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSG 120

Query: 121 GGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLL 180
           GGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLL
Sbjct: 121 GGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLL 180

Query: 181 TDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAA 240
           TDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAA
Sbjct: 181 TDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAA 240

Query: 241 AAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMH 300
           AAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMH
Sbjct: 241 AAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMH 300

Query: 301 RYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAA 360
           RYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAA
Sbjct: 301 RYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAA 360

Query: 361 AAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPG 420
           AAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPG
Sbjct: 361 AAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPG 420

Query: 421 GRLHGVHQHYQGAGTAVNGTVPLTHI 446
           GRLHGVHQHYQGAGTAVNGTVPLTHI
Sbjct: 421 GRLHGVHQHYQGAGTAVNGTVPLTHI 446


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  391 bits (1005), Expect = e-109
 Identities = 228/389 (58%), Positives = 260/389 (66%), Gaps = 53/389 (13%)

Query: 102 APGGAGKSSANAAGGANSGGGSSGGASGGGGG---TDQDRVKRPMNAFMVWSRGQRRKMA 158
           +PGGA ++  N +G A +GGG  GG  GGGGG    +QDRVKRPMNAFMVWSRGQRRKMA
Sbjct: 12  SPGGA-QAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMA 70

Query: 159 LENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLL 218
            ENPKMHNSEISKRLGA+WK++++AEKRPFIDEAKRLRA+HMKE+PDYKYRPRRKTKTLL
Sbjct: 71  QENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLL 130

Query: 219 KKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDT--------YTHVNGWANG 270
           KKDKYSL  GLL  GA    AA A           VGQRL++        Y HVNGWANG
Sbjct: 131 KKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQRLESPGGAAGGGYAHVNGWANG 190

Query: 271 AY-----------SLVQE-QLGYAQPPSM--SSPPPPPALP-------------PMHRYD 303
           AY           +++QE QL Y Q P    + P   PA P             PMHRYD
Sbjct: 191 AYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYD 250

Query: 304 MAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG---QQPATAAAAAA 360
           M  LQYSP+    +Q YM     +A+ SGYGG+   A AAAAAA G   Q  A AAAAAA
Sbjct: 251 MGALQYSPI--SNSQGYM-----SASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAA 303

Query: 361 AAAAM-SLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLP--PGGDAADAASP 417
           AAA+  +LG +GS+VKSEPS  PPA A HS+  C GDLR+MISMYLP   GGD A AA+ 
Sbjct: 304 AAASSGALGALGSLVKSEPSGSPPAPA-HSRAPCPGDLREMISMYLPAGEGGDPAAAAAA 362

Query: 418 LPGGRLHGVHQHYQGAGTAVNGTVPLTHI 446
               RLH + QHYQGAG  VNGTVPLTHI
Sbjct: 363 AAQSRLHSLPQHYQGAGAGVNGTVPLTHI 391


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score =  342 bits (877), Expect = 4e-94
 Identities = 194/377 (51%), Positives = 241/377 (63%), Gaps = 66/377 (17%)

Query: 76  MYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTD 135
           MY+++ETELK P           GP    G G            GG S+  A+GG     
Sbjct: 1   MYNMMETELKPP-----------GPQQTSGGG------------GGNSTAAAAGGNQKNS 37

Query: 136 QDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRL 195
            DRVKRPMNAFMVWSRGQRRKMA ENPKMHNSEISKRLGA+WKLL++ EKRPFIDEAKRL
Sbjct: 38  PDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRL 97

Query: 196 RAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVG 255
           RA+HMKE+PDYKYRPRRKTKTL+KKDKY+LP GLL PG  + A+     A   +   GV 
Sbjct: 98  RALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGA---GVN 154

Query: 256 QRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPP 315
           QR+D+Y H+NGW+NG+YS++Q+QLGY Q P +++      + PMHRYD++ LQY+ M   
Sbjct: 155 QRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNA-HGAAQMQPMHRYDVSALQYNSM--T 211

Query: 316 GAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVK 375
            +Q+YMN                  +   + +Y QQ             M+LG MGSVVK
Sbjct: 212 SSQTYMN-----------------GSPTYSMSYSQQ---------GTPGMALGSMGSVVK 245

Query: 376 SEPSSPPPAI--ASHSQRAC-LGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQG 432
           SE SS PP +  +SHS+  C  GDLRDMISMYL PG +  + A+P    RLH + QHYQ 
Sbjct: 246 SEASSSPPVVTSSSHSRAPCQAGDLRDMISMYL-PGAEVPEPAAP---SRLH-MSQHYQS 300

Query: 433 A---GTAVNGTVPLTHI 446
               GTA+NGT+PL+H+
Sbjct: 301 GPVPGTAINGTLPLSHM 317


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score =  181 bits (458), Expect = 2e-45
 Identities = 112/227 (49%), Positives = 139/227 (61%), Gaps = 15/227 (6%)

Query: 137 DRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLR 196
           D VKRPMNAFMVWSR QRRKMA ENPKMHNSEISKRLGA+WKLLT++EKRPFIDEAKRLR
Sbjct: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65

Query: 197 AVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQ 256
           A+HMKE+PDYKYRPRRK KTLLKKDK++ P      G A A   A  A A   +  G G 
Sbjct: 66  AMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGL 125

Query: 257 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPG 316
             ++       A  A +    ++ + Q  + ++     A         AG  YS ++  G
Sbjct: 126 VPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAA--------AGSPYS-LLDLG 176

Query: 317 AQSYMNVAAAAAAASG--YGGMAPSATAAAAAAYGQQPATAAAAAAA 361
           ++    +A  ++++SG  Y       TA A A +G   A AAAAAAA
Sbjct: 177 SK----MAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAA 219



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 39/120 (32%), Positives = 48/120 (40%), Gaps = 27/120 (22%)

Query: 324 AAAAAAASGYGGMAP----------SATAAAAAAYGQQPATAAAAAAAAAA--------- 364
           A A   A   GG+ P          +A AAAAAA    P +AAAAAAAAAA         
Sbjct: 113 AGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSL 172

Query: 365 MSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLH 424
           + LG   + + S  S  P A +     A  G      +        AA AA+   GG  H
Sbjct: 173 LDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAA--------AAAAAAAAAGGHTH 224



 Score = 30.0 bits (66), Expect = 4.4
 Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 16/98 (16%)

Query: 223 YSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYA 282
           Y+   G    GA A   AAAAAAAAA++  G      T++H +              GY 
Sbjct: 191 YASSLGYPTAGAGAFHGAAAAAAAAAAAAGG-----HTHSHPS----------PGNPGYM 235

Query: 283 QPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSY 320
            P + S+ P P   PP+    + G+   P + P   +Y
Sbjct: 236 IPCNCSAWPSPGLQPPLAYILLPGMG-KPQLDPYPAAY 272


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  165 bits (418), Expect = 7e-41
 Identities = 84/126 (66%), Positives = 94/126 (74%), Gaps = 11/126 (8%)

Query: 137 DRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLR 196
           D +KRPMNAFMVWSRGQRRKMA ENPKMHNSEISKRLGA+WKLL++AEKRP+IDEAKRLR
Sbjct: 6   DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65

Query: 197 AVHMKEYPDYKYRPRRKTKTLLKKDKYSLP-----------SGLLPPGAAAAAAAAAAAA 245
           A HMKE+PDYKYRPRRK K LLKKD+Y  P           +  LP GA+    +A   A
Sbjct: 66  AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKA 125

Query: 246 AAASSP 251
            A   P
Sbjct: 126 RAFLPP 131


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score =  146 bits (368), Expect = 4e-35
 Identities = 91/224 (40%), Positives = 116/224 (51%), Gaps = 20/224 (8%)

Query: 110 SANAAGGANSGGGSSGGASGGG--GGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNS 167
           +A AA  ++SG     GA      G    ++VKRPMNAFMVWS  QRR+MA +NPKMHNS
Sbjct: 18  AATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNS 77

Query: 168 EISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPS 227
           EISKRLGA WKLL + EKRPF++EAKRLRA H+++YPDYKYRPRRK K+           
Sbjct: 78  EISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS----------- 126

Query: 228 GLLPPGAAAAAAAAAAAAAAASSPV-GVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPS 286
                GA  +         A+  P+ G G      +   G+   +YS       Y     
Sbjct: 127 ----SGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGSYGSSHC 182

Query: 287 MSSPPPPPALPPMHRYDMAGL--QYSPMMPPGAQSYMNVAAAAA 328
               P P +LP         L   Y+  +PPG+ +  N   A A
Sbjct: 183 KLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGA 226


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score =  139 bits (350), Expect = 5e-33
 Identities = 75/159 (47%), Positives = 98/159 (61%), Gaps = 20/159 (12%)

Query: 133 GTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEA 192
           G  QDRVKRPMNAF+VWSR QRRKMALENP+M NSEISK+LG  WK+LT+AEK PF  EA
Sbjct: 54  GNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEA 113

Query: 193 KRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPV 252
           ++L+A+H ++YP+YKYRPRRK K L K         LLP   A+   +            
Sbjct: 114 QKLQAMHREKYPNYKYRPRRKAKMLPKN------CSLLPADPASVLCSEV---------- 157

Query: 253 GVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPP 291
               +LD   + +      +S ++ QLG+  P + +S P
Sbjct: 158 ----QLDNRLYRDDCTKATHSRMEHQLGHLPPINAASSP 192


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  133 bits (334), Expect = 4e-31
 Identities = 99/301 (32%), Positives = 138/301 (45%), Gaps = 38/301 (12%)

Query: 91  PTQAAGTGG-PAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVW 149
           P   AG G  P A   +        G A +  G+  GA+G   G  + R++RPMNAFMVW
Sbjct: 21  PAVMAGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKG--ESRIRRPMNAFMVW 78

Query: 150 SRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYR 209
           ++ +R+++A +NP +HN+E+SK LG  WK LT AEKRPF++EA+RLR  HM+++P+YKYR
Sbjct: 79  AKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYR 138

Query: 210 PRRKTKT-LLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTY------- 261
           PRR+ +   LK+ +     GL  P AAA        A       G+G +           
Sbjct: 139 PRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMD-----GLGLQFPEQGFPAGPP 193

Query: 262 ---THVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMP---P 315
               H+ G      SL         PP    P P P   P+   D     ++  MP   P
Sbjct: 194 LLPPHMGGHYRDCQSL-------GAPPLDGYPLPTPDTSPLDGVDPDPAFFAAPMPGDCP 246

Query: 316 GAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSL----GPMG 371
            A +Y     + A  S Y G             G +PA  +     A   +L    G MG
Sbjct: 247 AAGTY-----SYAQVSDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMG 301

Query: 372 S 372
           S
Sbjct: 302 S 302


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  128 bits (321), Expect = 1e-29
 Identities = 114/366 (31%), Positives = 148/366 (40%), Gaps = 61/366 (16%)

Query: 106 AGKSSANAAG---GANSGGGSSGGASGGGGGTDQD-------RVKRPMNAFMVWSRGQRR 155
           AG+SS + AG   G  S       AS GG   D          +KRPMNAFMVWS+ +RR
Sbjct: 16  AGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERR 75

Query: 156 KMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTK 215
           K+  ++P MHN+EISKRLG  WKLL D++K PFI EA+RLR  HM +YPDYKYRPR+K K
Sbjct: 76  KIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVK 135

Query: 216 TLLKKDKYSLPSGLLP-------------------PGAAAAAAAAAAAAAAASSPVGVGQ 256
           +       S  +   P                    G ++ A      A+   +     Q
Sbjct: 136 SGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQ 195

Query: 257 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPG 316
           +    + V G A G  S    +L  A            A         A  Q       G
Sbjct: 196 KKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA------SFAAEQ------AG 243

Query: 317 AQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAA------------AA 364
           A + + + AAA   S Y    PSA+A+A++A     A AA     A              
Sbjct: 244 AAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLG 303

Query: 365 MSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLH 424
            S  P+G V      S P  +       C  D         P     + AAS    GR  
Sbjct: 304 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPD--------APSLSGRSSAASSPAAGRSP 355

Query: 425 GVHQHY 430
             H+ Y
Sbjct: 356 ADHRGY 361



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 62/282 (21%), Positives = 106/282 (37%), Gaps = 43/282 (15%)

Query: 93  QAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRG 152
           +  G+GG    GG G  S+NA GG        GG + GGG   +   K+   + +    G
Sbjct: 157 KVGGSGGGGHGGGGGGGSSNAGGG--------GGGASGGGANSKPAQKKSCGSKVAGGAG 208

Query: 153 QRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRR 212
                     K H   I    G   K    A      ++A     + +    D+      
Sbjct: 209 GGVS------KPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADH------ 256

Query: 213 KTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAY 272
                     +SL     P  +A+A++AA+A+AA A+    + ++     ++ G   G  
Sbjct: 257 ----------HSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG-GLGTS 305

Query: 273 SLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMP--PGAQSYMNVAAAAAAA 330
           S     +G    PS           P+  Y+  G   SP  P   G  S  +  AA  + 
Sbjct: 306 SSPVGGVGAGADPS----------DPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSP 355

Query: 331 SGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGS 372
           + + G A    A+ A +     A+++A++ ++++ S G   S
Sbjct: 356 ADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSS 397



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 11/63 (17%)

Query: 89  GTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGS-----------SGGASGGGGGTDQD 137
           G     +G GG    GG G S+A   GG  SGGG+           S  A G GGG  + 
Sbjct: 155 GDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKP 214

Query: 138 RVK 140
             K
Sbjct: 215 HAK 217



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 15/43 (34%), Positives = 18/43 (41%)

Query: 91  PTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGG 133
           P +   +G   +   A  SS     G   GG   GG  GGGGG
Sbjct: 130 PRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGG 172


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  126 bits (316), Expect = 5e-29
 Identities = 105/337 (31%), Positives = 141/337 (41%), Gaps = 71/337 (21%)

Query: 93  QAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRG 152
           +A   GGP  PG               G    G    G   T    +KRPMNAFMVWS+ 
Sbjct: 8   RAKRDGGPPPPG--------------PGPAEEGAREPGWCKTPSGHIKRPMNAFMVWSQH 53

Query: 153 QRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRR 212
           +RRK+  + P MHN+EISKRLG  W+LL D+EK PF+ EA+RLR  HM +YPDYKYRPR+
Sbjct: 54  ERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRK 113

Query: 213 KTKTLLKKDKYSLPSG-----LLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGW 267
           K+K    K +   P G      L PG             AA  P+G              
Sbjct: 114 KSKGAPAKARPRPPGGSGGGSRLKPG---PQLPGRGGRRAAGGPLG-------------- 156

Query: 268 ANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAA 327
                       G A  P          L  +   +  G +   M+P G ++    A  A
Sbjct: 157 ------------GGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAG-RAARGQAERA 203

Query: 328 AAASGYGGMAPSATA---------------AAAAAYGQQPATAAAAAAAAAAMSL--GPM 370
              SG G  A +A +               AAAA  G++   A+   +      L  GP 
Sbjct: 204 QGPSGEGAAAAAAASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPA 263

Query: 371 G---SVVKSEPSSPPPAIASHSQ--RACLGDLRDMIS 402
           G   S +  +P   PP+  SH +    C  ++ +MI+
Sbjct: 264 GLDCSALDRDPDLQPPSGTSHFEFPDYCTPEVTEMIA 300


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  124 bits (311), Expect = 2e-28
 Identities = 74/206 (35%), Positives = 107/206 (51%), Gaps = 15/206 (7%)

Query: 56  PAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAG 115
           P  GA   P        AP   +  +T  +     P   A    PA+P    +S   +  
Sbjct: 6   PGYGAQDDPPARRDCAWAPGHGAAADT--RGLAAGPAALAAPAAPASPPSPQRSPPRSPE 63

Query: 116 GANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGA 175
               G   +G   G     D+ R++RPMNAFMVW++ +R+++A +NP +HN+ +SK LG 
Sbjct: 64  PGRYGLSPAG--RGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGK 121

Query: 176 DWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAA 235
            WK L  AEKRPF++EA+RLR  H++++P+YKYRPRRK +    +    L  GLL PG A
Sbjct: 122 AWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQA---RKARRLEPGLLLPGLA 178

Query: 236 A--------AAAAAAAAAAAASSPVG 253
                     AA+ +A A     P+G
Sbjct: 179 PPQPPPEPFPAASGSARAFRELPPLG 204


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  123 bits (309), Expect = 3e-28
 Identities = 101/316 (31%), Positives = 138/316 (43%), Gaps = 85/316 (26%)

Query: 134 TDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAK 193
           T    +KRPMNAFMVWS+ +RRK+  ++P MHN+EISKRLG  WK+L D+EK PFI EA+
Sbjct: 44  TASGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAE 103

Query: 194 RLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPP--------GAAAAAAAAAA-- 243
           RLR  HM +YPDYKYRPR+K     K D  + PS    P        G +A   A  A  
Sbjct: 104 RLRLKHMADYPDYKYRPRKKP----KMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKT 159

Query: 244 ------------AAAAASSPVGVGQRL---------DTYT----HVNGWANGAYSLV--- 275
                       A AAA +  G G+           D Y      V+G   G        
Sbjct: 160 SKGSSKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGGAGKTVKC 219

Query: 276 --------------QEQLGYAQPPSMSSPPP-------PPALPP---MHRYDMAGLQYSP 311
                         + QL   Q P      P       PP   P   + RY++A +  SP
Sbjct: 220 VFLDEDDDDDDDDDELQLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVAKVPASP 279

Query: 312 MM------PPGAQSYMNVAAAAAAASGYGGM-------------APSATAAAAAAYGQQP 352
            +      P GA  Y  V A A + +G G                P A  A + A  +  
Sbjct: 280 TLSSSAESPEGASLYDEVRAGATSGAGGGSRLYYSFKNITKQHPPPLAQPALSPASSRSV 339

Query: 353 ATAAAAAAAAAAMSLG 368
           +T++++++ +++ S G
Sbjct: 340 STSSSSSSGSSSGSSG 355



 Score = 32.3 bits (72), Expect = 0.89
 Identities = 24/59 (40%), Positives = 27/59 (45%), Gaps = 14/59 (23%)

Query: 94  AAGTGGPAAPGGA-------------GKSSANAAGGANSGGGSSGGASGGGGGTDQDRV 139
           AAG GG +A GGA             GK  A AA GA +G G +   SG  GG   D V
Sbjct: 142 AAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKA-AQSGDYGGAGDDYV 199



 Score = 29.6 bits (65), Expect = 5.8
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 8/69 (11%)

Query: 311 PMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYG--------QQPATAAAAAAAA 362
           P M P A+   + +   +AA G GG A      A  + G        + PA A A A A 
Sbjct: 124 PKMDPSAKPSASQSPEKSAAGGGGGSAGGGAGGAKTSKGSSKKCGKLKAPAAAGAKAGAG 183

Query: 363 AAMSLGPMG 371
            A   G  G
Sbjct: 184 KAAQSGDYG 192


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score =  120 bits (302), Expect = 2e-27
 Identities = 87/278 (31%), Positives = 130/278 (46%), Gaps = 32/278 (11%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G    +  VKRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LL +++KRPFI+
Sbjct: 96  GASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIE 155

Query: 191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASS 250
           EA+RLR  H K++PDYKY+PRR+      + +   P G    G  AA  A   +A     
Sbjct: 156 EAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHR 215

Query: 251 PVGVGQRLD--TYTHVNGWANG-----AYSLVQEQLGYAQPP----SMSSPPPP------ 293
             G G  +      H +G ++G          + Q G A P     SM     P      
Sbjct: 216 HPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGN 275

Query: 294 --------PALPPMHRYDMAGL-QYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAA 344
                     +  M  +D+A L QY P  P G   ++    ++ +A+GYG  +  A A+ 
Sbjct: 276 VDIGEISHEVMSNMETFDVAELDQYLP--PNGHPGHV----SSYSAAGYGLGSALAVASG 329

Query: 345 AAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPP 382
            +A+  +P   A    +   +          + P  PP
Sbjct: 330 HSAWISKPPGVALPTVSPPGVDAKAQVKTETAGPQGPP 367


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  119 bits (298), Expect = 6e-27
 Identities = 105/344 (30%), Positives = 147/344 (42%), Gaps = 81/344 (23%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G    + R++RPMNAFMVW++ +R+++A++NP +HN+E+SK LG  WK LT ++KRP++D
Sbjct: 37  GDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVD 96

Query: 191 EAKRLRAVHMKEYPDYKYRPRRKTK--------------TLLKKDKYSLPS--------- 227
           EA+RLR  HM++YP+YKYRPRRK +              + L +D+ +LP          
Sbjct: 97  EAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGAL 156

Query: 228 ------GLLPPGAAAAAAAAA-AAAAAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLG 280
                 G   PG A  +         A     G    +DTY +                G
Sbjct: 157 GEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPY----------------G 200

Query: 281 YAQPPSM-------------SSPPPPPALPPMHRYDMAGLQYSPMMPPGAQ--SYMNVAA 325
              PP M             SSP       P     + G  YSP   P     S+   + 
Sbjct: 201 LPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSL 260

Query: 326 AAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPP-- 383
           A   + G   M+P      + AY   PAT     +   A  LG +         SPPP  
Sbjct: 261 ALGQSPGVSMMSPVPGCPPSPAY-YSPATYHPLHSNLQA-HLGQL---------SPPPEH 309

Query: 384 ----AIASHSQRACLGDL-RDMISMYL--PPGGDAADAASPLPG 420
               A+   SQ   LGD+ R+    YL  P   D+A  A  L G
Sbjct: 310 PGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSG 353


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score =  115 bits (287), Expect = 1e-25
 Identities = 58/117 (49%), Positives = 78/117 (66%), Gaps = 3/117 (2%)

Query: 129 GGGGGT--DQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKR 186
           GGGGG    +  VKRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LL+++EKR
Sbjct: 90  GGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKR 149

Query: 187 PFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLP-PGAAAAAAAAA 242
           PF++EA+RLR  H K++PDYKY+PRR+             + L P PG  A   A A
Sbjct: 150 PFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEA 206


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score =  110 bits (276), Expect = 2e-24
 Identities = 47/83 (56%), Positives = 66/83 (79%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G   ++  VKRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LL ++EKRPF++
Sbjct: 97  GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156

Query: 191 EAKRLRAVHMKEYPDYKYRPRRK 213
           EA+RLR  H K++PDYKY+PRR+
Sbjct: 157 EAERLRVQHKKDHPDYKYQPRRR 179


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  104 bits (260), Expect = 1e-22
 Identities = 50/114 (43%), Positives = 72/114 (63%), Gaps = 3/114 (2%)

Query: 112 NAAGGANSGGGSSGGA---SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSE 168
           N +G ++   G S         G G+++  +KRPMNAFMVW++ +RRK+    P MHNS 
Sbjct: 140 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 199

Query: 169 ISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           ISK LG+ WK +T+ EK+P+ +E  RL   H+++YPDYKY+PR K   L+   K
Sbjct: 200 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 253


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  104 bits (260), Expect = 1e-22
 Identities = 50/114 (43%), Positives = 72/114 (63%), Gaps = 3/114 (2%)

Query: 112 NAAGGANSGGGSSGGA---SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSE 168
           N +G ++   G S         G G+++  +KRPMNAFMVW++ +RRK+    P MHNS 
Sbjct: 513 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 572

Query: 169 ISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           ISK LG+ WK +T+ EK+P+ +E  RL   H+++YPDYKY+PR K   L+   K
Sbjct: 573 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 626


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  104 bits (260), Expect = 1e-22
 Identities = 50/114 (43%), Positives = 72/114 (63%), Gaps = 3/114 (2%)

Query: 112 NAAGGANSGGGSSGGA---SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSE 168
           N +G ++   G S         G G+++  +KRPMNAFMVW++ +RRK+    P MHNS 
Sbjct: 526 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 585

Query: 169 ISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           ISK LG+ WK +T+ EK+P+ +E  RL   H+++YPDYKY+PR K   L+   K
Sbjct: 586 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 639


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score = 99.0 bits (245), Expect = 8e-21
 Identities = 48/131 (36%), Positives = 74/131 (56%)

Query: 92  TQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSR 151
           T  +   G   PG    +    A G  +   +       G  + +  +KRPMNAFMVW++
Sbjct: 554 TGKSNEDGKLGPGVIDLTRPEDAEGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAK 613

Query: 152 GQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPR 211
            +RRK+    P MHNS ISK LG+ WK +++ EK+P+ +E  RL  +H+++YP+YKY+PR
Sbjct: 614 DERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPR 673

Query: 212 RKTKTLLKKDK 222
            K   ++   K
Sbjct: 674 PKRTCIVDGKK 684


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 42/92 (45%), Positives = 64/92 (69%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G  + +  +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +++ EK+P+ +
Sbjct: 626 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 685

Query: 191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           E  RL  +H+++YP+YKY+PR K   ++   K
Sbjct: 686 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 717


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 42/92 (45%), Positives = 64/92 (69%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G  + +  +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +++ EK+P+ +
Sbjct: 586 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 645

Query: 191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           E  RL  +H+++YP+YKY+PR K   ++   K
Sbjct: 646 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 677


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 42/92 (45%), Positives = 64/92 (69%)

Query: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
           G  + +  +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +++ EK+P+ +
Sbjct: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648

Query: 191 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
           E  RL  +H+++YP+YKY+PR K   ++   K
Sbjct: 649 EQARLSKIHLEKYPNYKYKPRPKRTCIVDGKK 680


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 42/85 (49%), Positives = 61/85 (71%)

Query: 135 DQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKR 194
           +   +KRPMNAFMVW++ +RRK+    P MHNS ISK LG+ WK +T+ EK+P+ +E  R
Sbjct: 420 NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQAR 479

Query: 195 LRAVHMKEYPDYKYRPRRKTKTLLK 219
           L   H+++YPDYKY+PR K   +++
Sbjct: 480 LSRQHLEKYPDYKYKPRPKRTCIVE 504


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 35/73 (47%), Positives = 54/73 (73%)

Query: 139 VKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAV 198
           VKRPMNAFMVW+R  R  +A  NP  +N+EIS +LG +W  L++ +K+P+ DEA++++  
Sbjct: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396

Query: 199 HMKEYPDYKYRPR 211
           H +E+P + Y+PR
Sbjct: 397 HREEFPGWVYQPR 409



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 26/146 (17%)

Query: 283 QPPSMSSP--PPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSA 340
           +PP    P  P PP LP     +      + M PP +   ++ AA+A  AS  G      
Sbjct: 7   EPPPQPRPLRPAPPPLP----VEGTSFWAAAMEPPPSSPTLSAAASATLASSCG------ 56

Query: 341 TAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDM 400
               A A G QP       A    + + P   ++  +P +     A+ S +A L   R  
Sbjct: 57  ---EAVASGLQP-------AVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPD 106

Query: 401 ISMYLPPGGDAADAASPLPGGRLHGV 426
           + +  PP   A+D A+  P   LH V
Sbjct: 107 LRLLQPP--TASDGATSRP--ELHPV 128


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 35/73 (47%), Positives = 54/73 (73%)

Query: 139 VKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAV 198
           VKRPMNAFMVW+R  R  +A  NP  +N+EIS +LG +W  L++ +K+P+ DEA++++  
Sbjct: 337 VKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKEK 396

Query: 199 HMKEYPDYKYRPR 211
           H +E+P + Y+PR
Sbjct: 397 HREEFPGWVYQPR 409



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 39/146 (26%), Positives = 58/146 (39%), Gaps = 26/146 (17%)

Query: 283 QPPSMSSP--PPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSA 340
           +PP    P  P PP LP     +      + M PP +   ++ AA+A  AS  G      
Sbjct: 7   EPPPQPRPLRPAPPPLP----VEGTSFWAAAMEPPPSSPTLSAAASATLASSCG------ 56

Query: 341 TAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDLRDM 400
               A A G QP       A    + + P   ++  +P +     A+ S +A L   R  
Sbjct: 57  ---EAVASGLQP-------AVRRLLQVKPEQVLLLPQPQAQNEEAAASSAQARLLQFRPD 106

Query: 401 ISMYLPPGGDAADAASPLPGGRLHGV 426
           + +  PP   A+D A+  P   LH V
Sbjct: 107 LRLLQPP--TASDGATSRP--ELHPV 128


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 94/392 (23%), Positives = 141/392 (35%), Gaps = 54/392 (13%)

Query: 29  PFPPDSLAH-RPP----SSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETE 83
           P    ++AH RPP    S+ P    G     +P PG P P   +      P      E E
Sbjct: 74  PAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPT---TEEE 130

Query: 84  LKNPVGTPTQAAGTGG----------------PAAPGGAGKSSANAAGGANSGGGSSGGA 127
              P G P   + T                  P  PG     S +A            G 
Sbjct: 131 ASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGR 190

Query: 128 SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRP 187
           S      ++D ++RPMNAFM++S+  R  +   +P   N  +SK LG  W  L   EK+ 
Sbjct: 191 SPNK--REKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQK 248

Query: 188 FIDEAKRLRAVHMKEYPDYKY--RPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAA 245
           + D A +++  H K +PD+K+  + R+K+ +  K     L  G       + +    AAA
Sbjct: 249 YHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAA 308

Query: 246 AAASSPVGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMA 305
              SS + +     T    +  A G+ S   E+L     P  + P           +  +
Sbjct: 309 PGVSSEL-LSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARP---------RAFSHS 358

Query: 306 GLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAM 365
           G+         +Q+   +    +  + Y G  PS    A       P  A     A AA 
Sbjct: 359 GVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPG-----PFAAPGEGGALAAT 413

Query: 366 SLGPMGSVVKSEPSSPPPAIASHSQRACLGDL 397
              P+            P  AS SQRA   D+
Sbjct: 414 GRPPL-----------LPTRASRSQRAASEDM 434



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 94/416 (22%), Positives = 127/416 (30%), Gaps = 110/416 (26%)

Query: 3   PVRENSSGARSPRVPADLARSILISLPFPPDSLAH-RPPSSAPTESQGLFTVAAPAPGA- 60
           P+R    GA  P  P+   R     LP  P +    RP S    E  G   +AAP  G  
Sbjct: 570 PLRPPPPGAGGPATPSKATRF----LPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGG 625

Query: 61  ----------------------PSPPA-TLAHLLPAPAMYSLLETELKNPV----GTPTQ 93
                                 PS PA +LA+  PA  +     T + N V     TP  
Sbjct: 626 NILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVP 685

Query: 94  AAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQ 153
            A    P +  G  ++S N   GA +  G+     GG           P+   +V+S   
Sbjct: 686 IASKPFPTS--GRAEASPNDTAGARTEMGTGSRVPGGS----------PLGVSLVYS--D 731

Query: 154 RRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRK 213
           ++  A  +P  H       LG   K                               P   
Sbjct: 732 KKSAAATSPAPH-LVAGPLLGTVGKA------------------------------PATV 760

Query: 214 TKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWANGAYS 273
           T  L+    Y  P+   PP     A  A      A S  G G             NG   
Sbjct: 761 TNLLVGTPGYGAPA---PPAVQFIAQGAPGGGTTAGSGAGAGSG----------PNGPVP 807

Query: 274 LVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGY 333
           L     G  QP ++                  G+     + P     + VA A A A G 
Sbjct: 808 L-----GILQPGALGKA--------------GGITQVQYILPTLPQQLQVAPAPAPAPGT 848

Query: 334 GGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHS 389
              APS  A   +     P   +      AA +  P   +++S PS+PPP   S S
Sbjct: 849 KAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVS 904



 Score = 29.3 bits (64), Expect = 7.6
 Identities = 28/98 (28%), Positives = 41/98 (41%), Gaps = 12/98 (12%)

Query: 31   PPDSLAHRPPSSAPTESQGLFT-VAAPAPGAPSP---------PATLAHLLPAPAM-YSL 79
            P   L  +P   AP      +T  A  +P  P P         P T+A   P+ +  + +
Sbjct: 1219 PESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRV 1278

Query: 80   LETELKNPVGTPTQAAGTGGPA-APGGAGKSSANAAGG 116
                L+N    PT  +    PA APGG+ +SS+  A G
Sbjct: 1279 PGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAG 1316



 Score = 28.9 bits (63), Expect = 9.9
 Identities = 50/226 (22%), Positives = 73/226 (32%), Gaps = 35/226 (15%)

Query: 228 GLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYT------HVNGWANGAYSLVQEQLGY 281
           GL PPG +  AA           P G G  L T           G      S     L Y
Sbjct: 608 GLEPPGPSVIAAP----------PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAY 657

Query: 282 AQPPSMSSPPPPPALPPMHR---YDMAGLQYSPMMPPG-AQSYMNVAAAAAAASGYGGMA 337
             P +  S P    +  + R        +   P    G A++  N  A A    G G   
Sbjct: 658 GAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRV 717

Query: 338 PSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPPAIASHSQRACLGDL 397
           P  +    +       +AAA + A   ++   +G+V K+  +     + +    A     
Sbjct: 718 PGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPA 777

Query: 398 RDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNGTVPL 443
              I+   P GG  A + +               GAG+  NG VPL
Sbjct: 778 VQFIAQGAPGGGTTAGSGA---------------GAGSGPNGPVPL 808



 Score = 28.9 bits (63), Expect = 9.9
 Identities = 20/75 (26%), Positives = 29/75 (38%), Gaps = 15/75 (20%)

Query: 29  PFPPDSLAHRPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPV 88
           P P   +    PS+ P ++Q +  V AP PG        A LLP   +          P+
Sbjct: 882 PTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGS------AQLLPGKVLV---------PL 926

Query: 89  GTPTQAAGTGGPAAP 103
             P+ +   GG   P
Sbjct: 927 AAPSMSVRGGGAGQP 941


>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
          Length = 476

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 114/400 (28%), Positives = 158/400 (39%), Gaps = 77/400 (19%)

Query: 13  SPRVPADLARSILISLP----FPPDSLAHRPPSSAPTESQGLFTVAAPA---PGAPSPPA 65
           SPR+P+    S L  LP    F  D+L +   + + +      + AA +   PG  S  A
Sbjct: 50  SPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGSESTVSSEISSAAESRKKPGHYSEAA 109

Query: 66  TLAHL----------LPAPAMYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAG 115
             A +          L +P      + +  N  G     +  G   +  G+G  S +  G
Sbjct: 110 AEADMSSDVEVGCSALRSPGGLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLH--G 167

Query: 116 GANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMA-LENPKMHNSEISK--- 171
           G+   GGS G A+ GG G+  D+V+R   AF       R ++A LE      + +S+   
Sbjct: 168 GS---GGSGGSAALGGSGSGADQVRRYRTAFT------REQIARLEKEFYRENYVSRPRR 218

Query: 172 -RLGADWKLLTDAEK-----RPFIDEAKRLRAV--HMKEYPDYKYRPRRKTKT--LLKKD 221
             L A   L     K     R   D+ +RL     H  +   Y Y       T  L    
Sbjct: 219 CELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPADPSFYTYMMTHAAATGSLPYPF 278

Query: 222 KYSLPSGLLPP---GAAAAAAAAAAAAAAASSPVGVGQR-LDTYTHVNGWANGAYSLVQE 277
              +P    P     AAAAAAAA+ AAAAASSP     R LDT+                
Sbjct: 279 HSHVPLHYYPHVGVTAAAAAAAASGAAAAASSPFATSIRPLDTFR--------------- 323

Query: 278 QLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYG--- 334
                   ++S P   P L    R+   GL  +P    G  S  + AAAAAAA+      
Sbjct: 324 --------ALSHPYSRPELLCSFRHP--GLYQAPAAAAGLNSAASAAAAAAAAAAAASSA 373

Query: 335 ---GMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMG 371
              G  PS  +A  +      + +AAAAAAAAA +LG  G
Sbjct: 374 AAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRG 413



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/132 (28%), Positives = 50/132 (37%), Gaps = 5/132 (3%)

Query: 34  SLAHRPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQ 93
           S  H     AP  + GL + A+ A  A +  A  +    A A  S             +Q
Sbjct: 337 SFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQ 396

Query: 94  AAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGGTD---QDRVKRPMNAFMVWS 150
           +A     AA    G  S    GG   GGG  GG +G GGG+D        R  + F+ +S
Sbjct: 397 SAAAAAAAAAAALG--SRGGGGGGGGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFLPYS 454

Query: 151 RGQRRKMALENP 162
                K A+  P
Sbjct: 455 AAVLSKTAVSPP 466



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 28/96 (29%), Positives = 36/96 (37%)

Query: 38  RPPSSAPTESQGLFTVAAPAPGAPSPPATLAHLLPAPAMYSLLETELKNPVGTPTQAAGT 97
           RP         GL+   A A G  S  +  A    A A  S        P G     +  
Sbjct: 331 RPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCL 390

Query: 98  GGPAAPGGAGKSSANAAGGANSGGGSSGGASGGGGG 133
              ++   A  ++A AA   + GGG  GG  GGGGG
Sbjct: 391 SCHSSQSAAAAAAAAAAALGSRGGGGGGGGGGGGGG 426


>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
          Length = 596

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 95/423 (22%), Positives = 158/423 (37%), Gaps = 82/423 (19%)

Query: 10  GARSPRVPADL-ARSILISLPFPPDSLAHRPPSSA-------------PTESQGLFTVAA 55
           G   P +PAD+  ++ +   P PPD   + P S               P + Q ++ +  
Sbjct: 191 GNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITT 250

Query: 56  -----PAPGAPSPPATLAHLLP--APAMYSLLETELKNP-VGTPTQAAGTGGPAAPGGAG 107
                P P A +  A+++   P   P  ++L  T + +P + TPT               
Sbjct: 251 GGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQ------------ 298

Query: 108 KSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNS 167
           +SS +  G  +S   S    S       +  +K+P+NAFM++ +  R K+  E     ++
Sbjct: 299 ESSQSDVGSLHS---SKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESA 355

Query: 168 EISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPS 227
            I++ LG  W  L+  E+  + + A++ R +HM+ YP +  R     K   K+DK    +
Sbjct: 356 AINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGET 415

Query: 228 G-----LLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWA------NGAYSLVQ 276
                  L P  +       +A     +  G+ Q+       N W             +Q
Sbjct: 416 NEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQ-------NNWCGPCRRKKKCVRYIQ 468

Query: 277 EQLGYAQPPS-----MSSPPPPPAL---PPMHRYDMA-------------GLQYSPMMPP 315
            +     PPS     + SPPP P L   PP                     L +  MMPP
Sbjct: 469 GEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPP 528

Query: 316 GAQSYMNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVK 375
                +  A   A+A    G      AA       QPA  +++ A  +  SL    S+  
Sbjct: 529 PPALLLAEATHKASALCPNGALDLPPAAL------QPAAPSSSIAQPSTSSLHSHSSLAG 582

Query: 376 SEP 378
           ++P
Sbjct: 583 TQP 585


>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
          Length = 579

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 96/418 (22%), Positives = 156/418 (37%), Gaps = 89/418 (21%)

Query: 10  GARSPRVPADL-ARSILISLPFPPDSLAHRPPSSA-------------PTESQGLFTVAA 55
           G   P +PAD+  ++ +   P PPD   + P S               P + Q ++ +  
Sbjct: 191 GNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITT 250

Query: 56  -----PAPGAPSPPATLAHLLP--APAMYSLLETELKNP-VGTPTQAAGTGGPAAPGGAG 107
                P P A +  A+++   P   P  ++L  T + +P + TPT               
Sbjct: 251 GGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQ------------ 298

Query: 108 KSSANAAGGANSGGGSSGGASGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNS 167
           +SS +  G  +S   S    S       +  +K+P+NAFM++ +  R K+  E     ++
Sbjct: 299 ESSQSDVGSLHS---SKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESA 355

Query: 168 EISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPS 227
            I++ LG  W  L+  E+  + + A++ R +HM+ YP +  R     K   K+DK     
Sbjct: 356 AINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDK----- 410

Query: 228 GLLPPGAAAAAAAAAAAAAAASSPVGVGQRLDTYTHVNGWA------NGAYSLVQEQLGY 281
               PG     +A     A      G+ Q+       N W             +Q +   
Sbjct: 411 ---QPGETNDLSAPKKCRAR----FGLDQQ-------NNWCGPCRRKKKCVRYIQGEGSC 456

Query: 282 AQPPS-----MSSPPPPPAL---PPMHRYDMA-------------GLQYSPMMPPGAQSY 320
             PPS     + SPPP P L   PP                     L +  MMPP     
Sbjct: 457 LSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALL 516

Query: 321 MNVAAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEP 378
           +  A   A+A    G      AA       QPA  +++ A  +  SL    S+  ++P
Sbjct: 517 LAEATHKASALCPNGALDLPPAAL------QPAAPSSSIAQPSTSSLHSHSSLAGTQP 568


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,964,734
Number of Sequences: 37866
Number of extensions: 1480183
Number of successful extensions: 37217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 727
Number of HSP's successfully gapped in prelim test: 1103
Number of HSP's that attempted gapping in prelim test: 14797
Number of HSP's gapped (non-prelim): 14456
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.