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Search of human proteins with 30023847
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
(397 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 825 0.0
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 776 0.0
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 507 e-144
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 245 6e-65
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 235 6e-62
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 188 8e-48
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 182 5e-46
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 164 1e-40
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 163 2e-40
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 163 2e-40
gi|115387114 islet-1 [Homo sapiens] 161 1e-39
gi|50083287 LIM homeobox 8 [Homo sapiens] 157 1e-38
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 132 5e-31
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 130 2e-30
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 130 2e-30
gi|21361802 LIM domain only 3 [Homo sapiens] 119 4e-27
gi|47778935 LIM domain only 3 [Homo sapiens] 119 4e-27
gi|4505005 LIM domain only 1 [Homo sapiens] 118 8e-27
gi|5803072 LIM domain only 4 [Homo sapiens] 114 1e-25
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 97 3e-20
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 97 3e-20
gi|4505001 LIM domain kinase 1 [Homo sapiens] 94 2e-19
gi|194272196 actin binding LIM protein family, member 2 isoform ... 88 1e-17
gi|194272200 actin binding LIM protein family, member 2 isoform ... 86 4e-17
gi|194272198 actin binding LIM protein family, member 2 isoform ... 86 4e-17
gi|153792514 actin binding LIM protein family, member 2 isoform ... 86 6e-17
gi|194272202 actin binding LIM protein family, member 2 isoform ... 86 6e-17
gi|194272207 actin binding LIM protein family, member 2 isoform ... 85 1e-16
gi|194272204 actin binding LIM protein family, member 2 isoform ... 85 1e-16
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 825 bits (2131), Expect = 0.0
Identities = 397/397 (100%), Positives = 397/397 (100%)
Query: 1 MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD 60
MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD
Sbjct: 1 MLLETGLERDRARPGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSD 60
Query: 61 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV 120
CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV
Sbjct: 61 CHTPLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVV 120
Query: 121 CKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSP 180
CKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSP
Sbjct: 121 CKRQLATGDEFYLMEDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSP 180
Query: 181 KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKS 240
KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKS
Sbjct: 181 KPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKS 240
Query: 241 DKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGL 300
DKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGL
Sbjct: 241 DKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGL 300
Query: 301 AGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRV 360
AGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRV
Sbjct: 301 AGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRV 360
Query: 361 LAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF 397
LAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF
Sbjct: 361 LAGNGPSSDLSTGSSGGYPDFPASPASWLDEVDHAQF 397
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 776 bits (2004), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 26 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 85
REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR
Sbjct: 31 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 90
Query: 86 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY
Sbjct: 91 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 150
Query: 146 ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 205
ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF
Sbjct: 151 ETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 210
Query: 206 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 265
QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE
Sbjct: 211 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 270
Query: 266 MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ 325
MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ
Sbjct: 271 MGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQ 330
Query: 326 SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP 385
SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP
Sbjct: 331 SLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPDFPASP 390
Query: 386 ASWLDEVDHAQF 397
ASWLDEVDHAQF
Sbjct: 391 ASWLDEVDHAQF 402
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 507 bits (1306), Expect = e-144
Identities = 250/377 (66%), Positives = 299/377 (79%), Gaps = 16/377 (4%)
Query: 26 REIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKR 85
++IP CAGC+QHILD+FILK LDRHWHS CLKC+DC LA+RCFSR SVYCK+DFFKR
Sbjct: 25 QQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKR 84
Query: 86 FGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
FGTKC ACQ GIPPTQVVR+AQDFVYHLHCFAC++C RQLATGDEFYLMED RLVCK DY
Sbjct: 85 FGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDY 144
Query: 146 ETAKQR-EAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVW 204
ETAKQ ++EA AKRPRTTITAKQLETLK+AY SPKPARHVREQLSSETGLDMRVVQVW
Sbjct: 145 ETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVW 204
Query: 205 FQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQD-SDAEVSFPDEPSL 263
FQNRRAKEKRLKKDAGR RWGQ+++++KRSRG SK +K+S E SD+E+SF ++ L
Sbjct: 205 FQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQIL 264
Query: 264 AEMGPANGLYGSLGEPTQALGRPSGAL--GNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 321
+E+G N +YG++G+ T G L G+FS++ G + Y++LR GSPYG+P SP
Sbjct: 265 SELGHTNRIYGNVGDVT------GGQLMNGSFSMDGTG----QSYQDLRDGSPYGIPQSP 314
Query: 322 AAPQSLPGPQPLLSSLVYP-DTSLGLVPSGAPGGPPPMRVLAGNGPSSDLSTGSSGGYPD 380
++ SLP PLL+ L Y D++LG++ G +R +AG GP+SD+STGSS GYPD
Sbjct: 315 SSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAG-GPTSDISTGSSVGYPD 373
Query: 381 FPASPASWLDEVDHAQF 397
FP SP SWLDE+DH F
Sbjct: 374 FPTSPGSWLDEMDHPPF 390
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 245 bits (625), Expect = 6e-65
Identities = 157/418 (37%), Positives = 218/418 (52%), Gaps = 81/418 (19%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
CAGC++ ILDRF+L LDR WH KC++C +C T L+E+CFSR +YCK+DFF+RFGTKC
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKC 64
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY----- 145
A C GI P+ +VR+A+ V+HL+CF C+VC +QL+TG+E Y++++++ VCK DY
Sbjct: 65 AGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS 124
Query: 146 ----------------------------------------ETAKQREAEATA----KRPR 161
ETA E + + PR
Sbjct: 125 LKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPR 184
Query: 162 TTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK-DAG 220
TTI AKQLETLK+A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+ A
Sbjct: 185 TTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSAL 244
Query: 221 RQRWGQYFRNMKRSRG-GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEP 279
R +FR+ +R R G + D+ E S + D +N + + G P
Sbjct: 245 GARRHAFFRSPRRMRPLGGRLDE---SEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGPP 301
Query: 280 TQALGRPSGALGNFSLEHGGLAGPEQYRELRPGS-PYG-VPPSPAAPQSLPGPQPLLSSL 337
+QA S A +F G PGS P G + P A P + P+ +
Sbjct: 302 SQA---QSPADSSFLAASG------------PGSTPLGALEPPLAGPHAADNPR-FTDMI 345
Query: 338 VYPDTSLGLVPSGAPGGPPPMRVLAG----NGPSSDLSTGSSGGYPDFPASPASWLDE 391
+PDT PS PG P + + G GPS + GY + P L+E
Sbjct: 346 SHPDT-----PSPEPGLPGTLHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNE 398
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 235 bits (599), Expect = 6e-62
Identities = 153/416 (36%), Positives = 206/416 (49%), Gaps = 108/416 (25%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
CAGC + ILDRF+L LDR WH KC++C +C L E+CFSR +YCK+DFF+ FGTKC
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKC 63
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY----- 145
A C GI P+ +VRRA+ V+HL+CF C++C +QL+TG+E Y++++++ VCK DY
Sbjct: 64 AGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSS 123
Query: 146 ---------------------------------ETAKQREAEA----------TAKR--P 160
E+A + EA AKR P
Sbjct: 124 VAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGP 183
Query: 161 RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK-DA 219
RTTI AKQLETLK+A+ +PKP RH+REQL+ ETGL+MRV+QVWFQNRR+KE+R+K+ A
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSA 243
Query: 220 GRQRWGQYFRNMKRSRG---------------------------GSKSDKDSVQEGQDSD 252
R +FR+ +R R G + D +G S
Sbjct: 244 LGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSS 303
Query: 253 AEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRPSGALGNFSLEHGGLAGPEQYRELRPG 312
+ D P + GP+ G L P PS F+ LA P PG
Sbjct: 304 QAQTPVDLPFVPSSGPSGTPLGGLEHPLPG-HHPSSEAQRFT---DILAHP-------PG 352
Query: 313 SPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGAPGGPPPMRVLAGNGPSS 368
SP+ SLPGP +S+ V+ G PP L+ NG +S
Sbjct: 353 D------SPSPEPSLPGPLHSMSAEVF-------------GPSPPFSSLSVNGGAS 389
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 188 bits (477), Expect = 8e-48
Identities = 97/232 (41%), Positives = 128/232 (55%), Gaps = 36/232 (15%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 89
+C GC + ILDRF+L+ D WH +C++C+ C PL CF R + +YCK D+ K F K
Sbjct: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVK 93
Query: 90 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE--- 146
C C I P + V RAQ VYHL CF C VC+RQL GDEF L E +L+CK DYE
Sbjct: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQLLCKGDYEKER 152
Query: 147 --------------------------------TAKQREAEATAKRPRTTITAKQLETLKS 174
TA++ + KRPRT +T +Q K+
Sbjct: 153 ELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKA 212
Query: 175 AYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQ 226
++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L + +Q+ Q
Sbjct: 213 SFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQ 264
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 182 bits (462), Expect = 5e-46
Identities = 117/332 (35%), Positives = 161/332 (48%), Gaps = 52/332 (15%)
Query: 7 LERDRARPGAAAVCTLGGTREIP---LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHT 63
+E RPG A + L G+ + P +C GC + I DRF+++ + WH +CL+C+ C
Sbjct: 7 MEEHALRPGPATLGVLLGS-DCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQ 65
Query: 64 PLAERCFSRGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKR 123
L C+ R +YCK D+ + F KC+ C I PT+ V RA + VYHL CF C VC+R
Sbjct: 66 ALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCER 125
Query: 124 QLATGDEFYLMEDSRLVCKADYETAKQREAEAT--------------------------- 156
QL GDEF L E +L+CK DYE K + +
Sbjct: 126 QLRKGDEFVLKE-GQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSK 184
Query: 157 -----------AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWF 205
KRPRT +T +Q K+++ S KP R VRE L++ETGL +RVVQVWF
Sbjct: 185 GSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWF 244
Query: 206 QNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAE 265
QN+RAK K+L A R + Q +N +R + S EG + P + +
Sbjct: 245 QNQRAKMKKL---ARRHQQQQEQQNSQRL---GQEVLSSRMEGMMASYTPLAPPQQQIVA 298
Query: 266 MGPANGLYGSLGEPTQALGRPSGALGNFSLEH 297
M YGS +P Q P GN S+ H
Sbjct: 299 M--EQSPYGS-SDPFQQGLTPPQMPGNDSIFH 327
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 164 bits (415), Expect = 1e-40
Identities = 115/342 (33%), Positives = 161/342 (47%), Gaps = 61/342 (17%)
Query: 30 LCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDFFKRF 86
+C GC I D+FIL+ D WH+ CLKC++C L E C F R YCK D+ + F
Sbjct: 26 MCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLF 85
Query: 87 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
G KCA CQ+G + +V RA+D VYH+ CF C VC RQL GDEF L E L+C+AD+
Sbjct: 86 GIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLRE-HELLCRADHG 144
Query: 147 TAKQREAEATAKRP------------------------------------RTTITAKQLE 170
+R A + + P RT + KQL
Sbjct: 145 LLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLH 204
Query: 171 TLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQYFRN 230
TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+ K +Q Q +
Sbjct: 205 TLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK-KSILMKQLQQQQHSD 263
Query: 231 MKRSRG--------GSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPT-Q 281
+G GS ++ +G + + P +L+E L L +P Q
Sbjct: 264 KTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPPWKALSEF----ALQSDLDQPAFQ 319
Query: 282 AL--GRPSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSP 321
L SG+LGN S G +L P +P + PSP
Sbjct: 320 QLVSFSESGSLGNSS----GSDVTSLSSQL-PDTPNSMVPSP 356
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 163 bits (413), Expect = 2e-40
Identities = 86/225 (38%), Positives = 128/225 (56%), Gaps = 28/225 (12%)
Query: 14 PGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFS 71
P AA+ G +C+ C ILDR++LK + WH +CL+CS C T L ++ C+
Sbjct: 85 PSAASSVPSAGKN---ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYI 141
Query: 72 RGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEF 131
+ + ++CK D+F RFGTKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF
Sbjct: 142 KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEF 201
Query: 132 YLMEDSRLVCKADYET----------------------AKQREAEATAKRPRTTITAKQL 169
L+E+ +++C+ Y+T ++Q AKR RT+ TA+QL
Sbjct: 202 GLVEE-KVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQL 260
Query: 170 ETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
+ +++ + P ++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 261 QVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 163 bits (413), Expect = 2e-40
Identities = 86/225 (38%), Positives = 128/225 (56%), Gaps = 28/225 (12%)
Query: 14 PGAAAVCTLGGTREIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFS 71
P AA+ G +C+ C ILDR++LK + WH +CL+CS C T L ++ C+
Sbjct: 85 PSAASSVPSAGKN---ICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYI 141
Query: 72 RGESVYCKDDFFKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEF 131
+ + ++CK D+F RFGTKCA C I + VRRA+ YHL CFAC CKRQL+TG+EF
Sbjct: 142 KNKEIFCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEF 201
Query: 132 YLMEDSRLVCKADYET----------------------AKQREAEATAKRPRTTITAKQL 169
L+E+ +++C+ Y+T ++Q AKR RT+ TA+QL
Sbjct: 202 GLVEE-KVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQL 260
Query: 170 ETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
+ +++ + P ++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 261 QVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 305
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 161 bits (407), Expect = 1e-39
Identities = 87/228 (38%), Positives = 120/228 (52%), Gaps = 40/228 (17%)
Query: 26 REIPLCAGCDQHILDRFILKAL-DRHWHSKCLKCSDCHTPLAERC--FSRGESVYCKDDF 82
R I LC GC I D++IL+ D WH+ CLKC++C+ L E C F R YCK D+
Sbjct: 12 RLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDY 71
Query: 83 FKRFGTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCK 142
+ +G KCA C +G V RA+ VYH+ CF CV C RQL GDEF L ED L C+
Sbjct: 72 IRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDG-LFCR 130
Query: 143 ADYETAKQREAEA--------------------TAKRP----------------RTTITA 166
AD++ ++ A +A++P RT +
Sbjct: 131 ADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
Query: 167 KQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
KQL TL++ Y +P+P ++EQL TGL RV++VWFQN+R K+K+
Sbjct: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 157 bits (398), Expect = 1e-38
Identities = 81/210 (38%), Positives = 120/210 (57%), Gaps = 26/210 (12%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
+C C I+D+++LK D WH +CL CS C T L C+ + + ++CK D+F+R+G
Sbjct: 74 VCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRRYG 133
Query: 88 TKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYET 147
T+C+ C I T VRRA+ VYHL CFAC CKRQL+TG+EF L+E+ +++C+ Y+
Sbjct: 134 TRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEE-KVLCRVHYDC 192
Query: 148 A---KQREAE--------------------ATAKRPRTTITAKQLETLKSAYNTSPKPAR 184
+RE E AKR RT+ TA QL+ +++ + P
Sbjct: 193 MLDNLKREVENGNGISVEGALLTEQDVNHPKPAKRARTSFTADQLQVMQAQFAQDNNPDA 252
Query: 185 HVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
++L+ TGL RV+QVWFQN RA+ K+
Sbjct: 253 QTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 132 bits (332), Expect = 5e-31
Identities = 64/149 (42%), Positives = 86/149 (57%), Gaps = 4/149 (2%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
LCAGC I DR+ L A+D+ WH +CLKC +C L CFS+ S+YCK+D+++RF
Sbjct: 52 LCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFS 111
Query: 88 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
+CA C LGI +++V RA+D VYHL+CF C C + L TGD F M+DS + C+ +E
Sbjct: 112 VQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFG-MKDSLVYCRLHFE 170
Query: 147 TAKQREAEATAKRPRTTITAKQLETLKSA 175
Q E A A KSA
Sbjct: 171 ALLQGEYPAHFNHADVAAAAAAAAAAKSA 199
Score = 52.4 bits (124), Expect = 7e-07
Identities = 27/57 (47%), Positives = 36/57 (63%)
Query: 158 KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214
KR RT+ QL T+KS + + P +QL+ +TGL RV+QVWFQN RAK +R
Sbjct: 267 KRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR 323
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 70 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 129
Query: 88 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 130 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 188
Query: 147 TAKQRE 152
T Q E
Sbjct: 189 TLLQGE 194
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 22/199 (11%)
Query: 31 CAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDDFFKRFG 87
CA C I +++A D +H C CS C+ L + + VYC+ F
Sbjct: 133 CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE---- 188
Query: 88 TKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEFYLMEDS 137
Q PP T++ ++ V K + A G +
Sbjct: 189 ---TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSG 245
Query: 138 RLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETG 195
+AD+ Q+ + KR RT+ QL T+KS + + P +QL+ +TG
Sbjct: 246 CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTG 305
Query: 196 LDMRVVQVWFQNRRAKEKR 214
L RV+QVWFQN RAK +R
Sbjct: 306 LTKRVLQVWFQNARAKFRR 324
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 130 bits (327), Expect = 2e-30
Identities = 60/126 (47%), Positives = 82/126 (65%), Gaps = 4/126 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAER--CFSRGESVYCKDDFFKRFG 87
LCAGC I DR+ L A+D+ WH +CLKC +C L CF++ S+YCK+D+++RF
Sbjct: 61 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFS 120
Query: 88 T-KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
+CA C LGI +++V RA+D VYHL CF C C + L TGD F M+DS + C+A +E
Sbjct: 121 VQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFE 179
Query: 147 TAKQRE 152
T Q E
Sbjct: 180 TLLQGE 185
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 22/199 (11%)
Query: 31 CAGCDQHI-LDRFILKALDRHWHSKCLKCSDCHTPLA--ERCFSRGESVYCKDDFFKRFG 87
CA C I +++A D +H C CS C+ L + + VYC+ F
Sbjct: 124 CARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE---- 179
Query: 88 TKCAACQLGIPP----TQVVRRAQDFVYHLHCFACVVCK------RQLATGDEFYLMEDS 137
Q PP T++ ++ V K + A G +
Sbjct: 180 ---TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSG 236
Query: 138 RLVCKADYETAKQREAEAT--AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETG 195
+AD+ Q+ + KR RT+ QL T+KS + + P +QL+ +TG
Sbjct: 237 CNENEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTG 296
Query: 196 LDMRVVQVWFQNRRAKEKR 214
L RV+QVWFQN RAK +R
Sbjct: 297 LTKRVLQVWFQNARAKFRR 315
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 119 bits (299), Expect = 4e-27
Identities = 55/134 (41%), Positives = 84/134 (62%), Gaps = 6/134 (4%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 88 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQTDY 131
Query: 146 ETAKQREAEATAKR 159
E +E A R
Sbjct: 132 EEGLMKEGYAPQVR 145
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 119 bits (299), Expect = 4e-27
Identities = 55/134 (41%), Positives = 84/134 (62%), Gaps = 6/134 (4%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 88 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQTDY 131
Query: 146 ETAKQREAEATAKR 159
E +E A R
Sbjct: 132 EEGLMKEGYAPQVR 145
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 118 bits (296), Expect = 8e-27
Identities = 53/121 (43%), Positives = 81/121 (66%), Gaps = 6/121 (4%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
CAGC++ I DR++LKALD++WH CLKC+ C L E +++ + C+ D+ + FG
Sbjct: 24 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 83
Query: 88 T--KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
T CAAC IP ++V RA+D VYHL CFAC +C ++ GD+F+L +++ ++C+ DY
Sbjct: 84 TTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFL-KNNMILCQMDY 142
Query: 146 E 146
E
Sbjct: 143 E 143
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 114 bits (286), Expect = 1e-25
Identities = 53/123 (43%), Positives = 75/123 (60%), Gaps = 6/123 (4%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
CAGC I DRF+L A+D +WHS+CLKCS C L + C+++ + C++D+ + FG
Sbjct: 23 CAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFG 82
Query: 88 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
C+AC IP +++V RAQ VYHL CF C C+ +L GD F+ + S L C+ D
Sbjct: 83 NSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGS-LFCEHDR 141
Query: 146 ETA 148
TA
Sbjct: 142 PTA 144
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 88 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 144
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 148
Query: 145 YETAK 149
YE K
Sbjct: 149 YEWTK 153
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 88 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 144
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 148
Query: 145 YETAK 149
YE K
Sbjct: 149 YEWTK 153
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 96.7 bits (239), Expect = 3e-20
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 7/125 (5%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAE---RCFSRGESVYCKDDFFKRFG 87
C GC Q+I DR+ LKA+D++WH CL C C L E R + + C+ D+ + FG
Sbjct: 99 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 158
Query: 88 TK--CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKAD- 144
CA+C I ++ R +D VYHL CF C C++ GD YL+ +S +VC+ D
Sbjct: 159 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDR-YLLINSDIVCEQDI 217
Query: 145 YETAK 149
YE K
Sbjct: 218 YEWTK 222
>gi|4505001 LIM domain kinase 1 [Homo sapiens]
Length = 647
Score = 94.4 bits (233), Expect = 2e-19
Identities = 41/115 (35%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Query: 27 EIPLCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRF 86
E+P+CA C Q I D L+AL+ WH+ C +C DC L+ + + + ++CK D++ R+
Sbjct: 21 ELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARY 80
Query: 87 GTKCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVC 141
G C C I +V A + YH CF C+ C + GD + L+E S+L C
Sbjct: 81 GESCHGCSEQI-TKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYC 134
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 90 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADY 145
CA+C I Q ++ A + +H CF C C L+ Y +D +L CK DY
Sbjct: 25 CASCGQRIYDGQYLQ-ALNADWHADCFRCCDCSASLS---HQYYEKDGQLFCKKDY 76
>gi|194272196 actin binding LIM protein family, member 2 isoform 1
[Homo sapiens]
Length = 645
Score = 88.2 bits (217), Expect = 1e-17
Identities = 75/263 (28%), Positives = 104/263 (39%), Gaps = 25/263 (9%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNR 208
R+A T R + T T+ + A +TS P+R + +L E LD R +
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYRDLAA----- 315
Query: 209 RAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGP 268
+ + D R Y + S G D+ S EG D S + G
Sbjct: 316 -LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCRTSSPSSTGS 370
Query: 269 AN-GLYGSLGEPTQALGRPSGAL 290
+ G Y Q RP+G +
Sbjct: 371 VSLGRYTPTSRSPQHYSRPAGTV 393
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272200 actin binding LIM protein family, member 2 isoform 3
[Homo sapiens]
Length = 572
Score = 86.3 bits (212), Expect = 4e-17
Identities = 75/264 (28%), Positives = 102/264 (38%), Gaps = 25/264 (9%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNR 208
R+A T R + T T+ + A +TS P+R + +L E LD R +
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYRDLAA----- 315
Query: 209 RAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGP 268
+ + D R Y + S G D+ S EG D S + G
Sbjct: 316 -LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCRTSSPSSTGS 370
Query: 269 AN-GLYGSLGEPTQALGRPSGALG 291
+ G Y Q RP G
Sbjct: 371 VSLGRYTPTSRSPQHYSRPGSESG 394
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272198 actin binding LIM protein family, member 2 isoform 2
[Homo sapiens]
Length = 611
Score = 86.3 bits (212), Expect = 4e-17
Identities = 75/264 (28%), Positives = 102/264 (38%), Gaps = 25/264 (9%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNR 208
R+A T R + T T+ + A +TS P+R + +L E LD R +
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYRDLAA----- 315
Query: 209 RAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGP 268
+ + D R Y + S G D+ S EG D S + G
Sbjct: 316 -LPKSKAIYDIDRPDMISYSPYISHSAG----DRQSYGEGDQDDRSYKQCRTSSPSSTGS 370
Query: 269 AN-GLYGSLGEPTQALGRPSGALG 291
+ G Y Q RP G
Sbjct: 371 VSLGRYTPTSRSPQHYSRPGSESG 394
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|153792514 actin binding LIM protein family, member 2 isoform 6
[Homo sapiens]
Length = 521
Score = 85.9 bits (211), Expect = 6e-17
Identities = 78/264 (29%), Positives = 111/264 (42%), Gaps = 29/264 (10%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR--------- 199
R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYRDLAALPKSK 320
Query: 200 -VVQVWFQNRRAKEKRLKKDAG-RQRWG---QYFRNMKRSRGGSKSDKDSVQEGQDSDAE 254
+ + + + + AG RQ +G Q R+ K+ R S S SV G+ +
Sbjct: 321 AIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTS 380
Query: 255 VSFPDEPSLAEMGPANGLYGSLGE 278
S P S ++G GSL +
Sbjct: 381 RS-PQHYSRPAARRSDGEDGSLDQ 403
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272202 actin binding LIM protein family, member 2 isoform 4
[Homo sapiens]
Length = 559
Score = 85.9 bits (211), Expect = 6e-17
Identities = 78/264 (29%), Positives = 111/264 (42%), Gaps = 29/264 (10%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR--------- 199
R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYRDLAALPKSK 320
Query: 200 -VVQVWFQNRRAKEKRLKKDAG-RQRWG---QYFRNMKRSRGGSKSDKDSVQEGQDSDAE 254
+ + + + + AG RQ +G Q R+ K+ R S S SV G+ +
Sbjct: 321 AIYDIDRPDMISYSPYISHSAGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVSLGRYTPTS 380
Query: 255 VSFPDEPSLAEMGPANGLYGSLGE 278
S P S ++G GSL +
Sbjct: 381 RS-PQHYSRPAARRSDGEDGSLDQ 403
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272207 actin binding LIM protein family, member 2 isoform 7
[Homo sapiens]
Length = 470
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/171 (33%), Positives = 77/171 (45%), Gaps = 14/171 (8%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 199
R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
>gi|194272204 actin binding LIM protein family, member 2 isoform 5
[Homo sapiens]
Length = 531
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/171 (33%), Positives = 77/171 (45%), Gaps = 14/171 (8%)
Query: 31 CAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTKC 90
C GC I + L ALD+HWH C KC C L S+ YC+ D+ +FG +C
Sbjct: 153 CGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRC 212
Query: 91 AACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDS--RLVCKADYETA 148
+C+ I T V A + YH C CV C + A G+E YL S C
Sbjct: 213 DSCEKYI--TGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPAC------- 263
Query: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMR 199
R+A T R + T T+ + A +TS P+R + +L E LD R
Sbjct: 264 --RQAARTEDRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEI-LDYR 311
Score = 55.8 bits (133), Expect = 7e-08
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVY-CKDDFFKRFGT 88
LC C ++ +L+ D+++H KC C C LAE F + Y C D+ + +GT
Sbjct: 23 LCNTCG-NVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGT 81
Query: 89 KCAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGD 129
+C +C I V A YH CF C VC+ GD
Sbjct: 82 RCFSCDQFIEGEVV--SALGKTYHPDCFVCAVCRLPFPPGD 120
Score = 35.0 bits (79), Expect = 0.12
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 103 VRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE 146
V R QD +H+ CF C C LA G + + +C DY+
Sbjct: 35 VLRVQDKYFHIKCFVCKACGCDLAEGG--FFVRQGEYICTLDYQ 76
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,577,879
Number of Sequences: 37866
Number of extensions: 1203809
Number of successful extensions: 9316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 412
Number of HSP's successfully gapped in prelim test: 591
Number of HSP's that attempted gapping in prelim test: 6687
Number of HSP's gapped (non-prelim): 2649
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.