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Search of human proteins with 122937251
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
(1682 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 3510 0.0
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 711 0.0
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap... 697 0.0
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap... 577 e-164
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap... 207 5e-53
gi|163965366 nascent polypeptide-associated complex alpha subuni... 150 8e-36
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 139 2e-32
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 133 2e-30
gi|160707881 formin 2 [Homo sapiens] 129 2e-29
gi|55750053 atrophin-1 [Homo sapiens] 129 2e-29
gi|55750041 atrophin-1 [Homo sapiens] 129 2e-29
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 126 2e-28
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 120 1e-26
gi|47132519 Ras association and pleckstrin homology domains 1 is... 120 1e-26
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 119 3e-26
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 119 3e-26
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 119 3e-26
gi|116284392 mucin 2 precursor [Homo sapiens] 113 2e-24
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 112 4e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 112 4e-24
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 112 4e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 112 4e-24
gi|150170670 piccolo isoform 2 [Homo sapiens] 111 5e-24
gi|150378539 piccolo isoform 1 [Homo sapiens] 111 5e-24
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 110 9e-24
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 108 4e-23
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 105 3e-22
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 102 4e-21
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 102 4e-21
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 101 5e-21
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 3510 bits (9102), Expect = 0.0
Identities = 1682/1682 (100%), Positives = 1682/1682 (100%)
Query: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL
Sbjct: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE
Sbjct: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
Query: 121 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 180
HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL
Sbjct: 121 HDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLL 180
Query: 181 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 240
HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL
Sbjct: 181 HLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 240
Query: 241 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300
PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP
Sbjct: 241 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300
Query: 301 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL
Sbjct: 301 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
Query: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP
Sbjct: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
Query: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480
GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP
Sbjct: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480
Query: 481 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 540
PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS
Sbjct: 481 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 540
Query: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600
HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV
Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600
Query: 601 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 660
PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV
Sbjct: 601 PLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGV 660
Query: 661 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 720
GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA
Sbjct: 661 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 720
Query: 721 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP
Sbjct: 721 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
Query: 781 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 840
LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG
Sbjct: 781 LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPG 840
Query: 841 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 900
PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP
Sbjct: 841 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 900
Query: 901 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 960
PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE
Sbjct: 901 PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE 960
Query: 961 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 1020
EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN
Sbjct: 961 EAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGN 1020
Query: 1021 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1080
LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG
Sbjct: 1021 LDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPG 1080
Query: 1081 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1140
PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA
Sbjct: 1081 PPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAA 1140
Query: 1141 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1200
DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV
Sbjct: 1141 DVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPV 1200
Query: 1201 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1260
LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT
Sbjct: 1201 LLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLT 1260
Query: 1261 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1320
GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP
Sbjct: 1261 GTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDP 1320
Query: 1321 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1380
KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM
Sbjct: 1321 KNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYM 1380
Query: 1381 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1440
KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI
Sbjct: 1381 KVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPI 1440
Query: 1441 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1500
LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY
Sbjct: 1441 LDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERY 1500
Query: 1501 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1560
EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK
Sbjct: 1501 EWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKK 1560
Query: 1561 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1620
IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE
Sbjct: 1561 IAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLE 1620
Query: 1621 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1680
QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST
Sbjct: 1621 QYRTEELAQAYDAFTLVRARRARGQRRRALGQAAGTGFGSPAAPFPEPPPAFSPQAPAST 1680
Query: 1681 SR 1682
SR
Sbjct: 1681 SR 1682
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 711 bits (1834), Expect = 0.0
Identities = 333/506 (65%), Positives = 409/506 (80%), Gaps = 2/506 (0%)
Query: 1133 LTISHCAADVVRASRNAKVKGKFRESYL-SPAQSVKPKINTEEKLPREKLNPPTPSIYLE 1191
++I +A+V++A RN G S L +P + LP++KLNPPTPSIYLE
Sbjct: 887 VSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLE 946
Query: 1192 SKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQ 1251
+KRDAF P L QFCT+P NP+TVIRGLAG+L+L+LGLFSTKTLVEA+ EH VEVRTQ+ Q
Sbjct: 947 NKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQ 1006
Query: 1252 PSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTG 1311
P+DENWD TGT++IW CES+RSHTTIAKYAQYQASSFQESL+EE E + DS +
Sbjct: 1007 PADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSEST 1066
Query: 1312 TPPSSAPDPKN-HHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTI 1370
+ +S K IKFGTNIDLSD K+WK QL EL KLPAF+RV S GN+LSHVGHTI
Sbjct: 1067 SSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTI 1126
Query: 1371 LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGV 1430
LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWF V E YW ++ FC+++ +
Sbjct: 1127 LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNL 1186
Query: 1431 DYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTA 1490
++L GSWWP L+DLY +N+PVYRF+QRPGDLVWINAGTVHWVQA GWCNNIAWNVGPLTA
Sbjct: 1187 NFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTA 1246
Query: 1491 YQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQ 1550
QY+LA+ERYEWN++++VKSIVPM+H+SWN+AR +K+SDP LF+MIK+CLL+++K CQ
Sbjct: 1247 CQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTL 1306
Query: 1551 RESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRS 1610
RE+L+ AGK+I + GR K+EPA+YC+ C+VEVF++LFVT+E+ SR TY+VHC+ CAR+ S
Sbjct: 1307 REALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTS 1366
Query: 1611 AGLQGVVVLEQYRTEELAQAYDAFTL 1636
L+ VVLEQY+ E+L Q YD FTL
Sbjct: 1367 GNLENFVVLEQYKMEDLMQVYDQFTL 1392
Score = 66.6 bits (161), Expect = 2e-10
Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 9/181 (4%)
Query: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
MH VD G +A +E++A+ L S P +W GRC +SIG+ A +
Sbjct: 252 MHHTVDLLGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 305
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
S + + + +++L + A+ + W LG LYES
Sbjct: 306 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 365
Query: 121 HDSEEATRCYHSALRYGG--SFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWN 178
+ ++A +CY +A R + + L RI LQ AQL N GS Q++ K+LP +E+ W+
Sbjct: 366 NQPQDAIKCYLNATRSKSCSNTSALAARIKYLQ-AQLCNLPQGSLQNKTKLLPSIEEAWS 424
Query: 179 L 179
L
Sbjct: 425 L 425
Score = 33.5 bits (75), Expect = 1.8
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 18/138 (13%)
Query: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLR-----GVEPNPGIPGA 422
++ D+SV+ + ++A PS TT S +S +S ++GL G+E +
Sbjct: 809 TKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
Query: 423 D-----HYQTPALEVSHHGRLGPSAHSSRKPF--LGAPAATPHLSL-----PPGPSSPPP 470
D H +P + S + PS+ K LG + L PP P S P
Sbjct: 869 DLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPY 928
Query: 471 PPCPR-LLRPPPPPAWLK 487
PP P+ L PP P +L+
Sbjct: 929 PPLPKDKLNPPTPSIYLE 946
>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sapiens]
Length = 1347
Score = 697 bits (1800), Expect = 0.0
Identities = 342/589 (58%), Positives = 427/589 (72%), Gaps = 9/589 (1%)
Query: 1056 PAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKI----RLIKVE 1111
PA + AS P P P + + + SL+ P L L K +
Sbjct: 752 PAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNS-PHSGLHTVNGEGLGKSQ 810
Query: 1112 SGDKETFIASEVEERRLRMADLTISHC--AADVVRASRNAKVKGKFRESYL-SPAQSVKP 1168
S K + + +++S C + +V++A RN G L +P
Sbjct: 811 SSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRP 870
Query: 1169 KINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGL 1228
+ LP++KLNPPTPSIYLE+KRDAF P L QFCT+P+NP+TVIRGLAG+L+L+LGL
Sbjct: 871 PTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL 930
Query: 1229 FSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSF 1288
FSTKTLVEA+ EH VEVRTQ+ QP+DENWD TGT++IW CES+RSHTTIAKYAQYQASSF
Sbjct: 931 FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSF 990
Query: 1289 QESLQEEKESEDEESEEPDSTTGTPPSSAPDPKN-HHIIKFGTNIDLSDAKRWKPQLQEL 1347
QESL+EE E + + D+ + + +S K IKFGTNIDLSD K+WK QL EL
Sbjct: 991 QESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFKTIKFGTNIDLSDNKKWKLQLHEL 1050
Query: 1348 LKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1407
KLPAF RV S GN+L+HVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD
Sbjct: 1051 TKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1110
Query: 1408 CEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAG 1467
CEWF V E YW ++ FC+++ +++L SWWP L+DLY +N+PVYRF+QRPGDLVWINAG
Sbjct: 1111 CEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAG 1170
Query: 1468 TVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKI 1527
TVHWVQA GWCNNIAWNVGPLTA QY+LA+ERYEWN++K+VKS VPM+H+SWN+AR +K+
Sbjct: 1171 TVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLKSVKSPVPMVHLSWNMARNIKV 1230
Query: 1528 SDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILF 1587
SDP LF+MIK+CLL+ +K Q RE+LV AGK++ + GR DEPA+YC+ C+VEVFN+LF
Sbjct: 1231 SDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLF 1290
Query: 1588 VTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTL 1636
VT+E+ ++ TY+VHC CAR+ S L+ VVLEQY+ E+L Q YD FTL
Sbjct: 1291 VTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTL 1339
Score = 46.2 bits (108), Expect = 3e-04
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
Query: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
MH +D G +A +E++A+ L S P +W GRC +SIG+ A +
Sbjct: 249 MHHNMDLVGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 302
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
S + + + +++L + A+ + W LG LYES
Sbjct: 303 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 362
Query: 121 HDSEEATRCYHSALRYG--GSFAELGPRIGRLQQ-AQLWNFHTGSCQHRAKVLPPLEQVW 177
+ ++A +CY +A R + + L RI LQ + WN H P++QV+
Sbjct: 363 NQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHH------PVQQVY 416
Query: 178 NLL-------HLEHKR 186
+L HLE R
Sbjct: 417 SLCLTPQKLQHLEQLR 432
>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sapiens]
Length = 1240
Score = 577 bits (1487), Expect = e-164
Identities = 287/490 (58%), Positives = 352/490 (71%), Gaps = 9/490 (1%)
Query: 1056 PAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKI----RLIKVE 1111
PA + AS P P P + + + SL+ P L L K +
Sbjct: 752 PAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNS-PHSGLHTVNGEGLGKSQ 810
Query: 1112 SGDKETFIASEVEERRLRMADLTISHC--AADVVRASRNAKVKGKFRESYL-SPAQSVKP 1168
S K + + +++S C + +V++A RN G L +P
Sbjct: 811 SSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRP 870
Query: 1169 KINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGL 1228
+ LP++KLNPPTPSIYLE+KRDAF P L QFCT+P+NP+TVIRGLAG+L+L+LGL
Sbjct: 871 PTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL 930
Query: 1229 FSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSF 1288
FSTKTLVEA+ EH VEVRTQ+ QP+DENWD TGT++IW CES+RSHTTIAKYAQYQASSF
Sbjct: 931 FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSF 990
Query: 1289 QESLQEEKESEDEESEEPDSTTGTPPSSAPDPKN-HHIIKFGTNIDLSDAKRWKPQLQEL 1347
QESL+EE E + + D+ + + +S K IKFGTNIDLSD K+WK QL EL
Sbjct: 991 QESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFKTIKFGTNIDLSDNKKWKLQLHEL 1050
Query: 1348 LKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1407
KLPAF RV S GN+L+HVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD
Sbjct: 1051 TKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1110
Query: 1408 CEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAG 1467
CEWF V E YW ++ FC+++ +++L SWWP L+DLY +N+PVYRF+QRPGDLVWINAG
Sbjct: 1111 CEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAG 1170
Query: 1468 TVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKI 1527
TVHWVQA GWCNNIAWNVGPLTA QY+LA+ERYEWN++K+VKS VPM+H+SWN+AR +K+
Sbjct: 1171 TVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLKSVKSPVPMVHLSWNMARNIKV 1230
Query: 1528 SDPDLFKMIK 1537
SDP LF+MIK
Sbjct: 1231 SDPKLFEMIK 1240
Score = 46.2 bits (108), Expect = 3e-04
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
Query: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
MH +D G +A +E++A+ L S P +W GRC +SIG+ A +
Sbjct: 249 MHHNMDLVGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 302
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
S + + + +++L + A+ + W LG LYES
Sbjct: 303 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 362
Query: 121 HDSEEATRCYHSALRYG--GSFAELGPRIGRLQQ-AQLWNFHTGSCQHRAKVLPPLEQVW 177
+ ++A +CY +A R + + L RI LQ + WN H P++QV+
Sbjct: 363 NQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHH------PVQQVY 416
Query: 178 NLL-------HLEHKR 186
+L HLE R
Sbjct: 417 SLCLTPQKLQHLEQLR 432
>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sapiens]
Length = 1079
Score = 207 bits (528), Expect = 5e-53
Identities = 121/258 (46%), Positives = 156/258 (60%), Gaps = 8/258 (3%)
Query: 1056 PAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKI----RLIKVE 1111
PA + AS P P P + + + SL+ P L L K +
Sbjct: 752 PAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNS-PHSGLHTVNGEGLGKSQ 810
Query: 1112 SGDKETFIASEVEERRLRMADLTISHC--AADVVRASRNAKVKGKFRESYL-SPAQSVKP 1168
S K + + +++S C + +V++A RN G L +P
Sbjct: 811 SSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRP 870
Query: 1169 KINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGL 1228
+ LP++KLNPPTPSIYLE+KRDAF P L QFCT+P+NP+TVIRGLAG+L+L+LGL
Sbjct: 871 PTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL 930
Query: 1229 FSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSF 1288
FSTKTLVEA+ EH VEVRTQ+ QP+DENWD TGT++IW CES+RSHTTIAKYAQYQASSF
Sbjct: 931 FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSF 990
Query: 1289 QESLQEEKESEDEESEEP 1306
QESL+ + D S +P
Sbjct: 991 QESLRAGMQWCDLSSLQP 1008
Score = 46.2 bits (108), Expect = 3e-04
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
Query: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
MH +D G +A +E++A+ L S P +W GRC +SIG+ A +
Sbjct: 249 MHHNMDLVGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 302
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
S + + + +++L + A+ + W LG LYES
Sbjct: 303 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 362
Query: 121 HDSEEATRCYHSALRYG--GSFAELGPRIGRLQQ-AQLWNFHTGSCQHRAKVLPPLEQVW 177
+ ++A +CY +A R + + L RI LQ + WN H P++QV+
Sbjct: 363 NQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHH------PVQQVY 416
Query: 178 NLL-------HLEHKR 186
+L HLE R
Sbjct: 417 SLCLTPQKLQHLEQLR 432
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 150 bits (380), Expect = 8e-36
Identities = 232/959 (24%), Positives = 304/959 (31%), Gaps = 151/959 (15%)
Query: 196 PVKRAAEPPVVQ-PVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPP 254
P K P VV P P + P+ ++ + + T P G+P P P P
Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940
Query: 255 PPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYP 314
PP PP P G AT P W P + PP P
Sbjct: 941 TPPAATPPSPKGGPATPSP---------------KWAPTPPAATPPS------------P 973
Query: 315 YPAPAYTAHPPGHRLVPAA-PPGP--GPRPPGAESHGCLPATRPPGSDLRESRVQRSRMD 371
PA T P G PAA PP P GP P + PA PP S
Sbjct: 974 KGGPA-TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP-SPKGSPAATPFPKG 1031
Query: 372 SSVSPAAT-------TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
+S PAAT A P P P P T S + L+G P
Sbjct: 1032 ASTPPAATPPSPKGSPAATP-LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPA 484
PA S G P A + P G A PH P P++ PP P L PPP A
Sbjct: 1091 KGGPATP-SPKGAPMPPAATPPSP-KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 485 WLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPP 544
PA G + G P PA P P +G L P+ + T + TPP
Sbjct: 1149 -PTTPAATPPSPKGGLATPPPKG--APTTPAATP-PSPKGGLATPSPK-GAPTTPAATPP 1203
Query: 545 TP----PTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600
+P TP+ + + + SP G ++ P P P PPSP P PP
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK--GAPTTPAATPPSPKGGPATPPPK 1261
Query: 601 PLTLALPPAPPSSCHQNTSGSFRRPE---SPRPRVSFPKTPEVGPG-PPPGPLSKAPQPV 656
P PP++ + G P +P P V P +P+ GP PP P
Sbjct: 1262 G-----APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 657 PPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKE-----EE 711
PP P P PTP P LP + KE
Sbjct: 1317 PPSPKGSPGTPPP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 712 QQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT------TAPAVAVTTTTTTT------T 759
H+ G A PP + ++ SP T+P APA VT T T
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
Query: 760 TTTATQEEEKKPP--------PALPP---PPPLAKFPPPSQPQPPPP-----------PP 797
T KK P PA P P L PPS +PP P P
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494
Query: 798 PSPASL-LKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856
+PA + +L +V+ + A S+R P+ T + AT P + P
Sbjct: 1495 ATPAPMGAPTLPAVIPSSP---KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 857 AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP--LSLPPARSESEVL 914
A P P + + + A P P T P P L +PPA +
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
E + + T P+ A PA GT P + + + S +CK
Sbjct: 1612 EAPTPP----------AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKM 1661
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKS 1034
P+ + K P ++ + I +
Sbjct: 1662 G-------------------ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK 1702
Query: 1035 RPDLGGASKAKPPTAPAPPS-----APAPSAQPTP-------PSASVPGKKAREEAPGP 1081
P +S PP P P + P + P P S + GK A GP
Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761
Score = 118 bits (295), Expect = 6e-26
Identities = 232/1000 (23%), Positives = 330/1000 (33%), Gaps = 169/1000 (16%)
Query: 249 PPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGL--WSTLHGDAWGPER---KGSAPPERQ 303
P +P P P PP A +PP G+ S L A P+ + S
Sbjct: 728 PEIPKSVPSPSLPP------AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATA 781
Query: 304 EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
+ +L + P+P + P + P GP P P + S L E+
Sbjct: 782 SSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS--PVSPVEASFLPEN 839
Query: 364 RVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGAD 423
+ S S SPA T ++P+ PP G T S+ + S G+ P P
Sbjct: 840 SL--SFQGSKDSPATT-----HSPT-PPSPKGAPTPSAVTPLSPKGV--TLPPKETP--- 886
Query: 424 HYQTPALEVSHHGRLGPSAHSSRK-PFLGAPAATPHLS-LPPGPSSPPPPPCPRLLRPPP 481
TP++ + GP+ + ++ P L +++P + P P P P P+ PP
Sbjct: 887 ---TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943
Query: 482 ---PPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQ 538
PP+ GPA T P PP PP+ + T
Sbjct: 944 AATPPSPKGGPA-----------------TPSPKWAPTPPAAT------PPSPKGGPATP 980
Query: 539 DSHTPPTPPTPTTSSSNSNSGSHS--SSPAGPVSFPPPPYLARSIDPLPRPPS--PAQNP 594
PTPP T S + S +P P PP P + + P P+ S PA P
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 595 QDPPLVPLTLALP---PAPPSSCHQNTSGSFRRPE---SPRPRVSFPKTPEVGPGPPPGP 648
P P LP P P++ + G P +P P + P +P+ GP P
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP--- 1097
Query: 649 LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRK 708
S P+PP +G P + PA P G
Sbjct: 1098 -SPKGAPMPPAATPPSPKG----GLATPPHKGAPTTPAATPPSPKG-------------- 1138
Query: 709 EEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTT----TAT 764
G+A PP P +P P+ T P TT T + AT
Sbjct: 1139 ---------GLATPPPKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 765 QEEEKKP-PPALPPPPP---LAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRG 820
+ P PA PP P LA P P P PPSP L + + +G
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP--KGAP----T 1242
Query: 821 TGAAVSTRPGPLPTTQYSPGPPSGATALPPT----SAAPSAQGSPQPSASSSSQFSTSGG 876
T AA P P T G P+ A PP+ A P +G+P P+ + S GG
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP--SPKGG 1300
Query: 877 PWARERRAGEEPVPGPMTPTQPPPPLSLPP---ARSESEVLEEISRACETLVERVGRSAT 933
P + P P TP P PP A + V + TL S
Sbjct: 1301 PATSPPKGA--PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358
Query: 934 DPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDS 993
P P S E PPA GG A S KR
Sbjct: 1359 GPTTP--------SSKEGPTPPAATPSHKGGPAMTPPSPKR------------------G 1392
Query: 994 VGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGR-EKSRPDLGGASKAKPPTAPAP 1052
+G + A +P + + + + + + P + S K P AP
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452
Query: 1053 ---PSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIK 1109
P+ P+ PT P+ + P K E P P V+ + K + P + +
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPK---EPPAPKQVATSSSPKKAPATPAPMGAPTLPAV- 1508
Query: 1110 VESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKGKFRESYLSPAQSVKPK 1169
+ S KE + + RR A S+ +E+ + PA +V P
Sbjct: 1509 IPSSPKE--VPATPSSRR--------DPIAPTATLLSKKTPATLAPKEALIPPAMTV-PS 1557
Query: 1170 INTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPR 1209
+P K P TPS S A +P + P+
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Score = 112 bits (279), Expect = 4e-24
Identities = 202/813 (24%), Positives = 273/813 (33%), Gaps = 137/813 (16%)
Query: 194 GPPVKRAAEPP-----VVQPVPPAALSGPSGEEGLSPGGKRR---RGCNSEQTGLPP--- 242
G P AA PP + P P A + P+ GG +G + PP
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 243 GLPLPPPPLPPPPPPPPPPPPPLPGLATSP------PFQLTKPGLWSTLHGDAWGPERKG 296
G P PPP P PP PP GLAT P P +T P S G A P +
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP---SPKGGPATSPPKGA 1309
Query: 297 SAPPERQ--EQRHSLPHPYPYPAPAYTA----HPPGHRLVPAAPP----GP-------GP 339
PP + S P P AP A P G +PA P GP GP
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369
Query: 340 RPPGAE-SHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTT 398
PP A SH PA PP S R + + D + SPA +P +P + P P T
Sbjct: 1370 TPPAATPSHKGGPAMTPP-SPKRGPAIPSPKGDPT-SPAV----IPLSPKKAPATPVTRE 1423
Query: 399 SSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPH 458
+++ S +G P + + PA G PS S P L PA TP
Sbjct: 1424 GAATPS------KGDLTPPAVTPVSLKKAPATSAPKGGPATPS--SKGDPTL--PAVTPP 1473
Query: 459 LSL-PPGP------SSPPPPPC-PRLLRPPPPPAWLKG-----PACRAARED-----GEI 500
PP P SSP P P + P PA + PA ++R D +
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATL 1533
Query: 501 LEELFFGTEGPPRPAPPP---LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNS- 556
L + T P PP +P + P + + T S +PP T S+
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 557 ------------NSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTL 604
S S +P P PP P + P P+P P PP+ P +L
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSP------EKGPATPAPKGTPTSPPVTPSSL 1647
Query: 605 ALPPAPPSSCHQNTSGSFRRPESPRPRVSFP---KTPEVGPGPPPGPLSKAPQPVPPGVG 661
P P+S + + P P K V P P P+ AP P
Sbjct: 1648 KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK 1707
Query: 662 ELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAP 721
+ A P + P P + + P L + K D S + + H +P
Sbjct: 1708 KSSATSPPIC---PDPSAKNGSKGPLSTVAPAPLLPVQK--DSSKTAKGKDASH----SP 1758
Query: 722 QPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPL 781
+ PL P + +P T A ++ KP A P
Sbjct: 1759 KGPLAPPESKASTPL-----------------------TAAAFEKVLPKPESASVSAAPS 1795
Query: 782 AKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL-PTTQYSPG 840
P P P P PP L S VLE + A PL P S G
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS---KPLAPADEDELLPLIPPEPISGG 1852
Query: 841 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP 900
P + + P + G P P+ S+ Q T + +E VP
Sbjct: 1853 VPFQSVLV--NMPTPKSAGIPVPT-PSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQA 1909
Query: 901 PLSLPPARSESEVLEE-ISRACETLVERVGRSA 932
+ +E+ EE +S+A ++ E+ R A
Sbjct: 1910 TTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKA 1942
Score = 108 bits (270), Expect = 4e-23
Identities = 174/752 (23%), Positives = 249/752 (33%), Gaps = 130/752 (17%)
Query: 192 RGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPP--------- 242
+GGP A PP P PPAA + PS + GL+ +G + PP
Sbjct: 1252 KGGP----ATPPPKGAPTPPAA-TPPSLKGGLAT--PPHKGAPNPAVVTPPSPKGGPATS 1304
Query: 243 ---GLPLPPPPLPPPPP----PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGP--- 292
G P PP PP P PPP P P A +PP P L +T GP
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP-AVTPPSPKGTPTLPATTPSSKGGPTTP 1363
Query: 293 -ERKGSAPPERQEQRHSLP---HPYPYPAPAYTAHPPGHRLVPAA---PPGPGPRPPGAE 345
++G PP P P P PA + P G PA P P P
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS-PKGDPTSPAVIPLSPKKAPATPVTR 1422
Query: 346 SHGCLPA---TRPPG---SDLRESRVQRSRMDSSVSPAA-----TTACVPYAPSRPPGLP 394
P+ PP L+++ + +P++ A P +P PP
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
Query: 395 GTTTSSSSSSSSNT-GLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH--SSRKPFLG 451
TSSS + T G P + + + PA S + P+A S + P
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP--- 1539
Query: 452 APAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGP 511
A A +PP + P P P + P PA P+ + A + + G P
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA---TPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 512 PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSF 571
PP +V + PTPP T
Sbjct: 1597 KELLIPP---------------AVTSPSPKEAPTPPAVT--------------------- 1620
Query: 572 PPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPR 631
PP P + P P+P P PP+ P +L P P+S + + P
Sbjct: 1621 PPSP------EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 632 VSFP---KTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
P K V P P P+ AP P + A P + P P +
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC---PDPSAKNGSKGPLS 1731
Query: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT---------- 738
+ P L + K D S + + H +P+ PL P + +P
Sbjct: 1732 TVAPAPLLPVQK--DSSKTAKGKDASH----SPKGPLAPPESKASTPLTAAAFEKVLPKP 1785
Query: 739 DTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP-PPALPPPPPLAKFPPPSQPQPPPPPP 797
++A + AP+ V+ + T +++ P P L P P + + P P
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP 1845
Query: 798 PSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSA 857
P P S SVL + G V T P T+ + G SG + + S
Sbjct: 1846 PEPISGGVPFQSVLVNMP-TPKSAGIPVPTPSAKQPVTKNNKG--SG-------TESDSD 1895
Query: 858 QGSPQPSASSSSQFSTSGGPWARERRAGEEPV 889
+ P+ S+Q +T A EEPV
Sbjct: 1896 ESVPELEEQDSTQATTQQAQLAAAAEIDEEPV 1927
Score = 80.9 bits (198), Expect = 1e-14
Identities = 143/613 (23%), Positives = 208/613 (33%), Gaps = 99/613 (16%)
Query: 190 AKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPP 249
+ +GGP + E P PPAA G ++P +R P G P P
Sbjct: 1355 SSKGGPTTPSSKE----GPTPPAATPSHKGGPAMTPPSPKR----GPAIPSPKGDPTSPA 1406
Query: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLW--STLHGDAWGPERKGSAPPERQEQ-- 305
+P P P P G AT LT P + S A + G A P +
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 306 --RHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
+ P P PAP A + PA P P GA + LPA P S +E
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPAT-----PAPMGAPT---LPAVIP--SSPKEV 1516
Query: 364 RVQRSRMDSSVSPAAT-------------TACVPYA-----PSRPPGLPGTTTSSSSSSS 405
S ++P AT A +P A P + P +P + ++ SS
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576
Query: 406 SNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGP 465
+ P + + + P S L P A +S P A TP PP P
Sbjct: 1577 -----KEASSPPAVTPSTYKGAP----SPKELLIPPAVTSPSP---KEAPTPPAVTPPSP 1624
Query: 466 SSPPPPPCPR--LLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP------ 517
P P P+ PP P+ LK A ++ + ++G P P
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684
Query: 518 ---PLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSS---SPAGPVSF 571
P P + P + + S T P P P S+ N + G S+ +P PV
Sbjct: 1685 LVAPAPESTPIITAPTRKGPQTKKSSATSP-PICPDPSAKNGSKGPLSTVAPAPLLPVQ- 1742
Query: 572 PPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLA----LPPAPPSSCHQNTSGSFRRPES 627
A+ D P P P+ PLT A + P P S+ +
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS---------AA 1793
Query: 628 PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAE 687
P P VS P + P P P +PP LP+ + + P PL E+
Sbjct: 1794 PSPPVSLP----LAPSPVP--------TLPPKQQFLPSSPGLVLESPSKPLAPADEDELL 1841
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGV-APQPPLKEPFASLQSPFPTDTAPTTTA 746
I P+ ++ + + + AG+ P P K+P T++ +
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTPK---SAGIPVPTPSAKQPVTKNNKGSGTESDSDESV 1898
Query: 747 PAVAVTTTTTTTT 759
P + +T TT
Sbjct: 1899 PELEEQDSTQATT 1911
Score = 63.9 bits (154), Expect = 1e-09
Identities = 167/724 (23%), Positives = 237/724 (32%), Gaps = 146/724 (20%)
Query: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRL-VPAAPPGPGPRPPGAESHGCLPATRPPG 357
P E E + P P P L V AA PGP P C PA P
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPP----CSPA---PQ 54
Query: 358 SDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNP 417
+ Q S S + A+T VP+ P GT ++ + T L + P
Sbjct: 55 QCPLSAANQASPFPSPSTIASTPLEVPF----PQSSSGTALPLGTAPEAPTFLPNLIGPP 110
Query: 418 GIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLL 477
P A +P + + G SA L A PH S+ + PP LL
Sbjct: 111 ISPAALALASPMIAPTLKGTPSSSAP------LALVALAPH-SVQKSSAFPP-----NLL 158
Query: 478 RPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPP----------LPHREGFLG 527
PP A E G ++ P P+ P +P+ +G
Sbjct: 159 TSPPSVA---------VAESGSVIT-----LSAPIAPSEPKTNLNKVPSEVVPNPKGTPS 204
Query: 528 PPA-----------SRFSVGTQDSHTPPTPPTPTTSSSN-------------SNSGSHSS 563
PP S+ + + P T PT T + ++ S S
Sbjct: 205 PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSL 264
Query: 564 SPAGPVSFPPPPYLARSIDPLPRPPSPAQN--PQDPPLVPLTLALPPAPPSSCHQNTSGS 621
S GPVS PP L+ S LP S + P PP P++L AP HQ++ GS
Sbjct: 265 SLKGPVS--PPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAP---LHQSSFGS 319
Query: 622 FRRPESPRPR------------------VSFPKTPEVGPGPPPGPLSKAPQPVPPGVGEL 663
+ P S+P V P PL + VP V
Sbjct: 320 VQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIP-----PLPSRNEVVPATVAAF 374
Query: 664 PARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDES-----IRKEEEQQQHEAG 718
P P + P T + P G N+ S I K +
Sbjct: 375 PVVAPSVDKGPST--------ISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYP 426
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPP 778
+ Q P+ S T T +A TTT T + P + P
Sbjct: 427 LVAQMPV--------SSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPT 478
Query: 779 PPLAKFPPPSQPQPP------------PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
P A P P+ P PP P P L +SVL K+ T +
Sbjct: 479 SPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL--VKF---PTQKDLQ 533
Query: 827 TRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE 886
T P L +SP T PT P Q +P+ S S S S+ P + E +
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKDPT-VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592
Query: 887 EPVPGPMTPTQPPPPLSLP-PARSESEVLEEISRA----CETLVERVGRSATDPADPVDT 941
+ + P+ +P ++ P S + V++ S A L++ + T A P+++
Sbjct: 593 KSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLES 652
Query: 942 AEPA 945
A+PA
Sbjct: 653 ADPA 656
Score = 57.0 bits (136), Expect = 2e-07
Identities = 214/930 (23%), Positives = 298/930 (32%), Gaps = 164/930 (17%)
Query: 234 NSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHG--DAWG 291
+S T LP G P P PP P L L P + TL G +
Sbjct: 85 SSSGTALPLGTAPEAPTFLPNLIGPPISPAALA---------LASPMIAPTLKGTPSSSA 135
Query: 292 PERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPG------------- 338
P + P ++ + P P+ G + +AP P
Sbjct: 136 PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEV 195
Query: 339 -PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTT 397
P P G S C+ +T P + +Q + TT + P + TT
Sbjct: 196 VPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIA-----SPQVKDTT 250
Query: 398 TSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEV--SHHGRLGPSAHSSRKPFLGAPAA 455
SS S N G ++ P A T +L V S GP+ LG+ A
Sbjct: 251 ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLA 310
Query: 456 TPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPP-RP 514
H S +LL P A L P + D G P R
Sbjct: 311 PLHQSSFGSV---------QLLGQTGPSA-LSDPTVKTISVDHSST-----GASYPSQRS 355
Query: 515 APPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPP 574
PPLP R + + F V P P+T SS + S S S + A S P
Sbjct: 356 VIPPLPSRNEVVPATVAAFPVVA-----PSVDKGPSTISSITCSPSGSLNVATSFSLSPT 410
Query: 575 PYLARSIDPLP--RPPSPAQNPQDP----PLV---PLTLALPPAPPSSCHQNTSGSFRRP 625
L P P AQ P PLV P T+A P +F
Sbjct: 411 TSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTT----------TFEVA 460
Query: 626 ESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEP 685
P +S + P P + P P A R+ PP P +P
Sbjct: 461 TCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQV--ATTLRIPVSPPLP------DP 512
Query: 686 AEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTT 745
+ K LP + ++K Q + P PF+ Q+ T PT
Sbjct: 513 EDLKNLPSSV--LVKF----------PTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVL 560
Query: 746 APAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLL- 804
A + + +T+++ P L P LAK +P P P S S L
Sbjct: 561 PLVQAAPKNSPSFQSTSSS------PEIPLSPEATLAK-KSLGEPLPIGKPASSMTSPLG 613
Query: 805 -KSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQP 863
S ASV++ Y G +A GPL + S P+ A A P SA P+ G
Sbjct: 614 VNSSASVIKTDSYA--GPDSA-----GPL--LKSSLITPTVA-AFPLESADPA--GVAPT 661
Query: 864 SASSSSQFSTSGGPWAR---ERRAGEEPVP-GPMT--PTQPPPPLSLPPARSESEVLEEI 917
+A +S ++T+ P+ PV G +T P P + P A S +
Sbjct: 662 TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL 721
Query: 918 SRACETLVERVGRSATDPADPVDTAEPAD------SGTERLLP----PAQAKEEAGGVAA 967
A L + +S P+ P P S T L P P + E G +A
Sbjct: 722 --ATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779
Query: 968 VSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEE 1027
+ S + + + +RP + A P +GNL
Sbjct: 780 TASS--KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP-------IGNLSSPVSP 830
Query: 1028 IQGREKSRPDLG-GASKAKP-----PTAPAPPSAPAPSA---------------QPTPPS 1066
++ L SK P PT P+P AP PSA PTP
Sbjct: 831 VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSV 890
Query: 1067 ASVPGKKAREEAPGPPGVSRADMLKLRSLS 1096
++P K E P P +A L + S S
Sbjct: 891 VNLPFPK---EGPATPAPKQAPALSMTSSS 917
Score = 45.8 bits (107), Expect = 3e-04
Identities = 88/368 (23%), Positives = 125/368 (33%), Gaps = 91/368 (24%)
Query: 642 PGPP-PGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLA-NIM 699
PGP P P S APQ P + P TPLE F + + LP G A
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP 100
Query: 700 KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDT---APTTTAPAVAVTTTTT 756
L I PP+ +L SP T P+++AP V
Sbjct: 101 TFLPNLI---------------GPPISPAALALASPMIAPTLKGTPSSSAPLALV----- 140
Query: 757 TTTTTTATQEEEKKPPPALPPPP---------------PLAKFPP-------PSQPQPPP 794
+ Q+ PP L PP P+A P PS+ P P
Sbjct: 141 -ALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNP 199
Query: 795 PPPPSPASLLKS--------LASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPP---- 842
PSP ++ + +AS+ G V++ P PTT + P
Sbjct: 200 KGTPSPPCIVSTVPYHCVTPMASIQSG-----------VASLPQTTPTTTLAIASPQVKD 248
Query: 843 ---SGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
S P + S +G P A+ S ST P + GP TP P
Sbjct: 249 TTISSVLISPQNPGSLSLKGPVSPPAALS--LSTQSLPVV----TSSQKTAGPNTP--PD 300
Query: 900 PPLSLPPARSESEVLEEISRACETLVERVGRSA-TDPADPVDTAEPADSGT-----ERLL 953
P+SL S L + S L+ + G SA +DP + + + +G ++
Sbjct: 301 FPISL---GSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
Query: 954 PPAQAKEE 961
PP ++ E
Sbjct: 358 PPLPSRNE 365
Score = 31.2 bits (69), Expect = 8.9
Identities = 21/53 (39%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Query: 32 PPHPPPRSAWLPGGRCSASI-GQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTP 83
P PPP+ A P S G P LPA P S G + SK P A TP
Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 139 bits (350), Expect = 2e-32
Identities = 204/759 (26%), Positives = 260/759 (34%), Gaps = 162/759 (21%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPP----- 249
PP K AA P + P+ + L+ PS P G + R P+PPP
Sbjct: 287 PPRKDAA--PALGPLSSSPLATPS------PSGTKAR-------------PVPPPDNAAT 325
Query: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSL 309
PLP PP PP PLP SP SAPP Q +L
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSP------------------------SAPPSLQ----TL 357
Query: 310 PHPYPYPAPAYTAHPPGHRLVPA-APPGPGPRPPGAESHGCL-PATRPPGSDLRESRVQR 367
P P PA + PP P APP PP H P+ + P S L S +Q
Sbjct: 358 PSP---PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414
Query: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
+ S + AT + + +P + + + +S+ + L+ P P +
Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474
Query: 428 PALE-VSHHGRLGP-------SAHSSRKPF---LGAPAATPHLSLPPGPSSPPP----PP 472
PA+ +S + P ++HS + P + P T PP +PP PP
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534
Query: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPL--PHREGFLGPPA 530
L PPP E PP PAP PL P PP
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPH------------LETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 531 SRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPP---PYLARSIDPLPRP 587
+ S+ T PP +P S P P++ PPP P LA + PL P
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGL-------PSPPLSPLATPPPQAPPXLA--LPPLQAP 633
Query: 588 PSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF--PKTPEVGPG-- 643
PSP P PPL PL P AP + F P SP + F P +P V P
Sbjct: 634 PSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 644 PP---PGPLSKAPQPVPPGVGELPARGPRLFDFP--PTPLEDQFEEPAEFKILPDGLANI 698
PP P L+ P VPP P P P P PL P + P +
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA---APPLQVPPSPPASPPM 747
Query: 699 MKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTT 758
R V P PP P + L P P T P A+ + +
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
Query: 759 TTTTATQEEEKKP--PPALPPP--PPLAKFP----PPSQPQPP----PPPPPSPASLLKS 806
P P A PPP PP+ P PPS P P P PP+P
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP------ 861
Query: 807 LASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQ-GSPQPSA 865
G +VS GP T +PGPP PP S +PS+ P +
Sbjct: 862 -------------GPDTSVS---GPRLTLALAPGPP------PPPSRSPSSTLSGPDLAG 899
Query: 866 SSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSL 904
SSS ST E G + P PPP L
Sbjct: 900 HSSSATSTP------EELRGYDSGPEGGAAASPPPDAEL 932
Score = 123 bits (309), Expect = 1e-27
Identities = 226/928 (24%), Positives = 297/928 (32%), Gaps = 137/928 (14%)
Query: 242 PGLPLPPPPLPPPPPPPPPPPP----PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGS 297
PGL P PP P PPPP P G P G+ G A PE
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPR 76
Query: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG 357
A P R S PA A G R PA PGP S G T PG
Sbjct: 77 AGPTRSAGTSSRN-----PASRPPASGRGERAPPAKNTSPGP----VSSPGRASGTTRPG 127
Query: 358 ----SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGL 410
LR E V R + + +A +A S P PGT + + + S G
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGT 185
Query: 411 RGVEPNPGI-----PGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATP---HLSLP 462
P P P + + S H PS + R+P G P LS
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 463 PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHR 522
P S P P P PA P + L+ L PPR P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKG-------LQALRPPQVTPPRKDAAPA--- 295
Query: 523 EGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSP--AGPVSFPPP-PYLAR 579
LGP +S S T P P +++ + SP A P+ PP P
Sbjct: 296 ---LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
Query: 580 SIDPLPRPPSPAQNPQDPPLVPLTLALPPA----PPSSC-HQNTSGSFRRPESPRPRVSF 634
S+ LP PP+ + P + + PP+ PP H TS S + P SP S
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412
Query: 635 PKTPEVG--------------PGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLED 680
T +G P L+ +P P + P P +P
Sbjct: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP--LSLPASPPLQ 470
Query: 681 QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQ----------QHEAGVAPQPPLKEPFA 730
PA + + ++ L S+ Q + ++ +AP P L+ P A
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALS-SLASHSPQAPLSSLIMPPLETQSSLAP-PSLQTPPA 528
Query: 731 SLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQP 790
SL +P P + P+ P + T + TT P P PP PL PP +
Sbjct: 529 SLTTP-PLENLPSLAPPPLQ--TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 791 QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP- 849
PPP +P +L L T + LP Q P PP+ P
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 850 --PTSAAPSAQG--------SPQPSASSSSQFSTSGGPWARERRAGEEPV-PGPMTPTQP 898
P+ AP+A SP PS + FS P PV P P+Q
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP----------PVSPSATPPSQA 695
Query: 899 PPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQA 958
PP L+ PP + A+ P P T P + PP Q
Sbjct: 696 PPSLAAPPLQVPPSP-----------------PASPPMSPSATPPP-QAPPPLAAPPLQV 737
Query: 959 KEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVL 1018
+S S + + P AK + P + L
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797
Query: 1019 GNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAP----APSAQ--PTPPSASVPGK 1072
L G+ P AS P A PP AP AP Q P+PP++
Sbjct: 798 QALPSPPASFPGQAPFSPS---ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 1073 KAREEAPGPPGVSRADMLKLRSLSEGPP 1100
R PGP L L +L+ GPP
Sbjct: 855 PRRPPTPGPDTSVSGPRLTL-ALAPGPP 881
Score = 121 bits (304), Expect = 5e-27
Identities = 241/979 (24%), Positives = 315/979 (32%), Gaps = 199/979 (20%)
Query: 242 PGLPLPPPPLPPPPPPPPPPPPPLP---------GLATSPPFQLTKPGLWSTLHGDAWGP 292
P P P PP P PPPP P G P G+ G A P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-----GGATIP 71
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPA 352
E A P R S PA A G R PA PGP S G
Sbjct: 72 ESAPRAGPTRSAGTSS-----RNPASRPPASGRGERAPPAKNTSPGP----VSSPGRASG 122
Query: 353 TRPPG----SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSS 405
T PG LR E V R + + +A +A S P PGT + + + S
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP--TPGTPSPAMARRS 180
Query: 406 SNTGLRGVEPNPG-----IPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATP--- 457
G P P P + + S H PS + R+P G P
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 458 HLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP 517
LS P S P P P PA P + L+ L PPR
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG-------LQALRPPQVTPPRKDAA 293
Query: 518 PLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSP--AGPVSF-PPP 574
P LGP +S S T P P +++ + SP A P+ PP
Sbjct: 294 PA------LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 575 PYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPA----PPSSC-HQNTSGSFRRPESPR 629
P S+ LP PP+ + P + + PP+ PP H TS S + P SP
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 630 PRVSFPKTPEVG--------------PGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPP 675
S T +G P L+ +P P + P P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP--LSLPA 465
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQ----------QHEAGVAPQPPL 725
+P PA + + ++ L S+ Q + ++ +AP P L
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQAL-SSLASHSPQAPLSSLIMPPLETQSSLAP-PSL 523
Query: 726 KEPFASLQS------------PFPTDTAPTTT---------------APAVAVTTTTTTT 758
+ P ASL + P T +AP TT AP +TT T
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Query: 759 TTTTATQEEEKKP----PP--ALPPPP--PLAKFPPPSQP-------QPPPPPPPSPASL 803
++ AT + P PP LP PP PLA PP + P Q PP PP SP
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 804 LKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP--GPPSGATALPPTSAAPSAQGSP 861
+ S A S P P +SP PP +A PP+ A PS P
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703
Query: 862 ---QPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEIS 918
PS +S S S P P Q PPPL+ PP
Sbjct: 704 LQVPPSPPASPPMSPSATP-----------------PPQAPPPLAAPP------------ 734
Query: 919 RACETLVERVGRSATDPADPVDTAEPADSGTERLL--PPAQAKEEAGGVAAVSGSCKRRQ 976
L A+ P P T P LL PP Q +S K
Sbjct: 735 -----LQVPPSPPASPPMSPSATPPPR---VPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 977 KEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRP 1036
+ ++ P + A P + +L + S ++ P
Sbjct: 787 Q------------APPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQAPP 833
Query: 1037 DLGGASKAKPPTAPAPPSAPAPSAQPTP-PSASVPGKK-AREEAPGPP---------GVS 1085
L PP+ PA P+ AP PTP P SV G + APGPP +S
Sbjct: 834 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893
Query: 1086 RADMLKLRSLSEGPPKELK 1104
D+ S + P+EL+
Sbjct: 894 GPDLAGHSSSATSTPEELR 912
Score = 113 bits (283), Expect = 1e-24
Identities = 234/933 (25%), Positives = 302/933 (32%), Gaps = 204/933 (21%)
Query: 20 GGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAP---LPPSHGSSSGHPSKPYY 76
GG+ A S P P RSA G +PP PP+ +S G S P
Sbjct: 63 GGIGGATIPESAPRAGPTRSA---GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 77 APGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRY 136
A G P PL Q GL + +E R SAL
Sbjct: 120 ASGTTRPGPL------------------GQKGLRISAEETVARGKATEAPKR---SALSA 158
Query: 137 GGSFAELGPRIGRLQQAQLWNFHTGSCQ-------HRAKVLPPLEQVWNLLHLEHKRNYG 189
G GP G A + A+ PP E G
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE--------------G 204
Query: 190 AKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPP 249
++ V A+E +P PAA PS GL R +S T L P
Sbjct: 205 PRKS---VSSASEHSTTEP-SPAARRRPSAGGGLQRPASR--SLSSSATPLSSPARSGPS 258
Query: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKG--SAPPERQEQRH 307
P P P P GL P Q+T P + A GP + P +
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA---PALGPLSSSPLATPSPSGTKAR 315
Query: 308 SLPHPYPYPAPAYTAHPPGHRL---VPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESR 364
+P P P PP L +P APP P PP ++ PAT P
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA-PPSLQTLPSPPATPP--------- 365
Query: 365 VQRSRMDSSVSPAATTACVPYAPSR----PPGLPGTTTSSS-SSSSSNTGLRGVEPNPGI 419
S P+ TT + PS P +P + TS S + S L ++ +
Sbjct: 366 -------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 420 PGADHYQTPALEVSHHG-RLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLR 478
+P L+ +H + P + PA+TP P SPP P L
Sbjct: 419 G------SPTLQATHSFLTMSPRQTQASLTSPSRPASTP-------PDSPPLQ-APLSLP 464
Query: 479 PPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQ 538
PP PA I + P P + PP TQ
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP----LSSLIMPPLE-----TQ 515
Query: 539 DSHTPP---TPPTPTTSSSNSNSGSHSSSPAGPVSFP-------PPPYLARSIDPLPRPP 588
S PP TPP T+ N S + P S P PP A PL PP
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC--PLQAPP 573
Query: 589 SPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGP 648
SP P PP P ++A PP P++P P ++ P + P PP P
Sbjct: 574 SPLTTP--PPETPSSIATPP----------------PQAP-PALASPPLQGL-PSPPLSP 613
Query: 649 LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRK 708
L+ P PP + P + P P+P PA + P LA ++
Sbjct: 614 LATPPPQAPPXLALPPLQAP------PSP-------PASPPLSP--LATPSPQAPNALAV 658
Query: 709 EEEQQQHEAGVAPQPPLKEPFASLQSP--FPTDTAPTTTAPAVAVTTTTTTTTTTTATQE 766
Q P PP++ PF+ SP P+ T P+ P++A
Sbjct: 659 HLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA--------------- 701
Query: 767 EEKKPPPALPPPPPLAKFPPPSQPQPPPP--PPPSPASLLKSLASVLEGQKYCYRGTGAA 824
PP +PP PP + PP S PPP PPP A L+ S A
Sbjct: 702 ----PPLQVPPSPPAS--PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP---MSPSAT 752
Query: 825 VSTRPGPL---PTTQYSPGPPSG---------ATALPPTSAAPSAQGSPQPSASSSSQFS 872
R PL P Q P PP+ PP A P Q P P AS Q
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ-- 810
Query: 873 TSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
P++ P+ P P Q PP L+ P
Sbjct: 811 ---APFSPSASLPMSPLATP--PPQAPPVLAAP 838
Score = 111 bits (277), Expect = 7e-24
Identities = 195/755 (25%), Positives = 250/755 (33%), Gaps = 166/755 (21%)
Query: 3 RAVDPPGARAARE--AFALGGLSCAGAWSSCP------PHPPPRSAWLPGGRCSASIG-Q 53
+A+ PP R+ A ALG LS + + P P PPP +A P A++
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP---LPATLPPS 334
Query: 54 PPLPAPLPPSHGSSSGHPS----------KPYYAPGAPTPRPLHGK--------LESLHG 95
PPL PLP + S S PS P AP + T P+ ++ H
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 96 CVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQL 155
L+ P P L + T L+ SF + PR Q Q
Sbjct: 395 LTSPSLQAPPSPLALSSL----------QATTSLGSPTLQATHSFLTMSPR-----QTQA 439
Query: 156 WNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEP---PVVQPV--- 209
PPL+ +L PP++ + P P+ P+
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSL------------PASPPLQTSLSPAVSPLSSPLTIH 487
Query: 210 PPAALSGPSGEEGLSPGGKRRRGCNSEQTGL-PPGLPLPPPPLPPPP--------PPP-- 258
P ALS + +P Q+ L PP L PP L PP PPP
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 259 -----------PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH 307
PP P P +PP LT P PPE
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTP-------------------PPETPS--- 585
Query: 308 SLPHPYPYPAPAYTAHP----PGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
S+ P P PA + P P L P A P PP A LP + P S
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATP-----PPQAPPXLALPPLQAPPSPPASP 640
Query: 364 RVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGAD 423
+ S +P A + AP PP P S +S P+ P
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL- 699
Query: 424 HYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPP--GPSSPP--PPPCPRLLRP 479
P L+V P S P P A P L+ PP P SPP PP P P
Sbjct: 700 --AAPPLQVPPSPPASPPMSPSATP---PPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Query: 480 PPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQD 539
P P L P + PP P P LP PP + ++ T
Sbjct: 755 PRVPPLLAAPPLQV-----------------PPSP-PASLPMSPLAKPPPQAPPALATPP 796
Query: 540 SHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPP---PYLARSIDPLPRPPSPAQNP-- 594
P+PP + + + S P P++ PPP P LA + L PPSP +P
Sbjct: 797 LQALPSPPASFPGQAPFSPSA--SLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTL 852
Query: 595 QDPPLVP------------LTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGP 642
Q P P LTLAL P PP ++ S + P+ S TPE
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 643 GPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTP 677
G GP A PP EL A P + P P
Sbjct: 913 GYDSGPEGGAAASPPPD-AELAACHPAAWSRGPAP 946
Score = 75.5 bits (184), Expect = 4e-13
Identities = 127/508 (25%), Positives = 171/508 (33%), Gaps = 107/508 (21%)
Query: 451 GAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--PAWLK--GPACRAAREDGEILEELFF 506
GA A TP + PG +P PP P RPPPP PA L+ G A R+
Sbjct: 11 GAAARTP-AARAPGLLTPRPPGSP---RPPPPVTPAALRVLGAAGAVGRK---------- 56
Query: 507 GTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPA 566
PL R G +G T P PT + +S+ N S PA
Sbjct: 57 -----------PLAERAGGIGG-------ATIPESAPRAGPTRSAGTSSRNPASR--PPA 96
Query: 567 GPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPE 626
PP S P+ P + + PL L + + T + E
Sbjct: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-------EETVARGKATE 149
Query: 627 SPRPRVSFPKTPEVGPGPPPGPLSKA--------------PQPVPPGVGELPARGPRLFD 672
+P+ GP PG S A P+P P P GPR
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR--K 207
Query: 673 FPPTPLEDQFEEPA-EFKILPDGLANIMKMLDESIRKEEEQQQHEAGV---------APQ 722
+ E EP+ + P + + S+ A AP
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267
Query: 723 PPLKEPFASLQSPFPTDTAP--TTTAPAVAVTTTTTTTTTTTATQEEEKKPPP---ALPP 777
P + LQ+ P P APA+ +++ T + + + PPP A P
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Query: 778 PPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQY 837
P L PP + P P PP PS L++L S A ++ P TT
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPS-----------PPATPPSQAPPSMTTPP 376
Query: 838 SPGPPSGAT----ALPPTSAAPSAQGSPQPSASSSSQFSTS-GGPWAR--------ERRA 884
PPS T +P + +PS Q P P A SS Q +TS G P + R
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 885 GEEPVPGPMTPTQPPP-------PLSLP 905
+ + P P PP PLSLP
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLP 464
Score = 48.5 bits (114), Expect = 5e-05
Identities = 88/400 (22%), Positives = 130/400 (32%), Gaps = 51/400 (12%)
Query: 717 AGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP 776
AG + PL E + ++AP A T++ + A+ E+ PP
Sbjct: 50 AGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT 109
Query: 777 PPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQ 836
P P++ P + P P L+ A + + + T+
Sbjct: 110 SPGPVSS---PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 837 YSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE----EPVPGP 892
+PG PS A A + AA + G P+P+ S+ + T G P A E EP P
Sbjct: 167 PTPGTPSPAMARR-SRAAGTEVGLPRPAPSARPRPPTEG-PRKSVSSASEHSTTEPSPAA 224
Query: 893 MTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD-PADPVDTAEPADSGTER 951
L P +RS S +S R G SA P P ++P G +
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 952 LLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPK 1011
L PP A+ S P KA+ P
Sbjct: 280 LRPPQVTPPRKDAAPALG-------------------PLSSSPLATPSPSGTKARPVPPP 320
Query: 1012 EKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPS---APAPSAQP---TPP 1065
+ + + + P L PP+ APPS P+P A P PP
Sbjct: 321 DNA----------ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 1066 SASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKI 1105
S + P +A P + L SL + PP L +
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-QAPPSPLAL 409
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 133 bits (334), Expect = 2e-30
Identities = 198/732 (27%), Positives = 248/732 (33%), Gaps = 133/732 (18%)
Query: 242 PGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPE 301
P P P PP P PPPP P + G A RK A
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAAL--------------RVLGAAGAVGRKPLAERA 62
Query: 302 RQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG---- 357
++P P P T+ PP APP P S G T PG
Sbjct: 63 GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 358 SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVE 414
LR E V R + + +A +A S P PGT + + + S G
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGP--TPGTPSPAMARRSRAAGTEVGL 180
Query: 415 PNPG-----IPGADHYQTPALEVSHHGRLGPSAHSSRKPFLG-----------APAATPH 458
P P P + + S H PS + R+P G + +ATP
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP- 239
Query: 459 LSLP--PGPSSPPPPPCPRLLRPPPPPAW--LKGPACRAARED-GEILEELFFGTEGPPR 513
LS P GPS+ P P P P L+ P R+D L L P
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 514 PAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNS--GSHS---SSPAGP 568
P+ PP P PP S+ T S P TPP+ T+S S + +HS S P P
Sbjct: 300 PSAPPSPS-----APP----SLQTLPS-PPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 569 VSFPP---PPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRP 625
++ PP PP LA + PL PPSP P PPL PL P AP + F P
Sbjct: 350 LATPPPQAPPALA--LPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 626 ESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPT--PLEDQFE 683
P P V P +P PP P + P PP + P + P PP P+
Sbjct: 405 --PSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSAT 457
Query: 684 EPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTA 741
P + P LA L K Q P L P AS Q+PF +
Sbjct: 458 PPPQ---APPPLAAPPLQL----AKPPPQAPPALATPPLQALPSPPASFPGQAPF----S 506
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQ---------- 791
P+ + P + T A + P P P + PP P
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 792 ---PPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATAL 848
P PPPPPS +S +S L G G + S P Y GP GA A
Sbjct: 567 ALAPGPPPPPS-----RSPSSTLSGPDL----AGHSSSATSTPEELRGYDSGPEGGAAAS 617
Query: 849 PPTSA--------------AP-----SAQGSPQPSASSSSQFSTSGGPWARERRAGEE-- 887
PP A AP A G+P P ++ S G E E
Sbjct: 618 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 677
Query: 888 PVPGPMTPTQPP 899
P PG + P P
Sbjct: 678 PAPGALDPGPSP 689
Score = 110 bits (276), Expect = 9e-24
Identities = 181/755 (23%), Positives = 250/755 (33%), Gaps = 171/755 (22%)
Query: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH 307
P L P PP P PPPP+ A + G A RK A
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALR-------------VLGAAGAVGRKPLAERAGGIGGA 68
Query: 308 SLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQR 367
++P P P T+ PP APP P S G T PG L + ++
Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP-LGQKGLRI 127
Query: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
S ++ AT A P + S+ + +G P PG P +
Sbjct: 128 SAEETVARGKATEA------------PKRSALSAGARRDTSG-----PTPGTP------S 164
Query: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLP-PGPSSPPPPPCPRLLRPPPPPAWL 486
PA+ A SR AA + LP P PS+ P PP
Sbjct: 165 PAM-----------ARRSR-------AAGTEVGLPRPAPSARPRPPT------------- 193
Query: 487 KGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546
+GP + E P PA P G L PASR S TP +
Sbjct: 194 EGPRKSVSSASEHSTTE--------PSPAARRRPSAGGGLQRPASR---SLSSSATPLSS 242
Query: 547 PTPTTSSSNSN--SGSHSSSPAG--------PVSFPPPPYLARSIDPLPRPPSPAQNPQD 596
P + S+ + +H S P P PP A ++ PL P +P
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302
Query: 597 PPL--VPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQ 654
PP P +L P+PP++ + S P + T P PP PL+ P
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSP-------TLQATHSFLPSPPLSPLATPPP 355
Query: 655 PVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQ 714
PP + P + P P+P PA + P LA ++ Q
Sbjct: 356 QAPPALALPPLQAP------PSP-------PASPPLSP--LATPSPQAPNALAVHLLQAP 400
Query: 715 HEAGVAPQPPLKEPFASLQSP--FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPP 772
P PP++ PF+ SP P+ T P+ P++A PP
Sbjct: 401 FSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA-------------------PP 439
Query: 773 PALPPPPPLAKFPPPSQPQPPP----------------PPPPSPASLLKSLASVLEGQKY 816
+PP PP + PP S PP PPP +P +L L
Sbjct: 440 LQVPPSPPAS--PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 817 CYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGG 876
+ G A + LP + + PP PP AAP Q P P AS + Q
Sbjct: 498 SF--PGQAPFSPSASLPMSPLATPPPQA----PPVLAAPLLQVPPSPPASPTLQ-----A 546
Query: 877 PWARERRAGEEPVPGP-----MTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRS 931
P + V GP + P PPPP P + L S + + E +
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 932 ATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVA 966
+ P + P D+ P A ++ A +A
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 641
Score = 107 bits (266), Expect = 1e-22
Identities = 176/681 (25%), Positives = 232/681 (34%), Gaps = 131/681 (19%)
Query: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258
+A E P + A SG +P R S G GLP P P P
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR--RSRAAGTEVGLPRPA----PSARPR 190
Query: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAP 318
PP P ++++ T+P + A G +R R P +P
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-------GLQRPASRSLSSSATPLSSP 243
Query: 319 AYTAHPPGHRLVPAAPPGPG-PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
A + P R P AP P P+P G L A RPP + S SP
Sbjct: 244 ARSG--PSARGTPRAPAHPSQPKPKG------LQALRPPQVTPPRKDAAPALGPLSSSPL 295
Query: 378 AT-TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHG 436
AT + P +PS PP L + ++ S T G +P L+ +H
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG--------------SPTLQATHSF 341
Query: 437 RLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL--LRPPPPPAWLKGPACRAA 494
P P P A P L+LPP + P PP P L L P P A P A
Sbjct: 342 LPSPPLSPLATP---PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA----PNALAV 394
Query: 495 REDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSS 554
+L+ F +PPP P + PPAS PP P+ T S
Sbjct: 395 ----HLLQAPF---------SPPPSPPVQAPFSPPAS-----------PPVSPSATPPSQ 430
Query: 555 NSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP------ 608
+ S A P+ PP P + + P PP A P P PL LA PP
Sbjct: 431 -----APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQLAKPPPQAPPA 483
Query: 609 --APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP-QPVPPGVGELPA 665
PP + SF P S P +P P P P+ AP VPP P
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 666 -RGPRLFDFPPTPLED-QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQP 723
+ PR PPTP D P L G P P
Sbjct: 544 LQAPRR---PPTPGPDTSVSGPRLTLALAPG-------------------------PPPP 575
Query: 724 PLKEPFASLQSP-FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP------ 776
P + P ++L P ++ T+ P + A+ + + P
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 777 PPPPLAKFPPPSQPQP-PPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT 835
P PPLA P P P PP P A L ++ EG + T A + PGP P T
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET-EGPE---SATPAPGALDPGPSPGT 691
Query: 836 ---QYSPGPPSGATALPPTSA 853
+ + G +GA++ P A
Sbjct: 692 SGGKAAAGAGAGASSRSPKQA 712
Score = 89.7 bits (221), Expect = 2e-17
Identities = 187/707 (26%), Positives = 233/707 (32%), Gaps = 102/707 (14%)
Query: 451 GAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--PAWL-----------KGPACRAARED 497
GA A TP + PG +P PP P RPPPP PA L K A RA
Sbjct: 11 GAAARTP-AARAPGLLTPRPPGSP---RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 498 GEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS---HTPPTPPTPTTSSS 554
G + E GP R + PP R G PPA S G S + T P P
Sbjct: 67 GATIPE-SAPRAGPTRTSRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124
Query: 555 NSNSGSHSSSPAGPVSFPPPPYLAR-----SIDPLPRPPSPAQNPQDPPL---VPLTLAL 606
S + + P L+ + P P PSPA + V L
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 607 P---PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG---PPPGPLSKAPQPVPPGV 660
P P PP+ + + S + P + + P G G P LS + P+
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---- 240
Query: 661 GELPAR-GPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGV 719
PAR GP P P P++ K P GL + + + G
Sbjct: 241 -SSPARSGPSARGTPRAP-----AHPSQPK--PKGL---QALRPPQVTPPRKDAAPALGP 289
Query: 720 APQPPLKEPFASL----QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP---P 772
PL P S +P T P+ A + TT+ + T AT P P
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 773 PALPPP--PPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPG 830
A PPP PP PP Q PP PP SP + S A S P
Sbjct: 350 LATPPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406
Query: 831 PLPTTQYSP--GPPSGATALPPTS-----AAPSAQGSPQPSASSSSQFSTSGGPWARERR 883
P +SP PP +A PP+ AAP Q P P AS S + P A
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 884 AGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAE 943
A P+ P Q PP L+ PP ++ SA+ P P+ T
Sbjct: 467 AA-PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-----FSPSASLPMSPLAT-- 518
Query: 944 PADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSV-GRRPREGR 1002
PP QA Q R SV G R
Sbjct: 519 ----------PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568
Query: 1003 AKAKAKVPKEKSRRVLGNLDLQS---------EEIQGREKSRPDLGGASKAKPPTAPAPP 1053
A P L DL EE++G + S P+ GGA+ + PP A
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPE-GGAAASPPPDAELAA 626
Query: 1054 SAPAP-SAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGP 1099
PA S P PP A A P G AD L +EGP
Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673
Score = 89.4 bits (220), Expect = 3e-17
Identities = 139/532 (26%), Positives = 177/532 (33%), Gaps = 107/532 (20%)
Query: 192 RGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL 251
R GP + P P P G + L P + + P PL PL
Sbjct: 245 RSGPSARGTPRAPAHPSQPK-----PKGLQALRPP----QVTPPRKDAAPALGPLSSSPL 295
Query: 252 PPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPH 311
P P PP P P L T P T P +T G P Q LP
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS-----------PTLQATHSFLPS 344
Query: 312 P-------YPYPAPAYTAHPP--GHRLVPAAPP-----GPGPRPPGAESHGCL------- 350
P P AP A PP PA+PP P P+ P A + L
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 351 --PATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNT 408
P + P S V S S +P + A P PP P + S++ +
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Query: 409 GLRG-----VEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPP 463
L +P P P A TP L+ PS +S F G +P SLP
Sbjct: 465 PLAAPPLQLAKPPPQAPPA--LATPPLQAL------PSPPAS---FPGQAPFSPSASLPM 513
Query: 464 GPSSPPPPPCPRLLR------PPPPPAWLKGPACRAAREDGEILEELFFGTEGP------ 511
P + PPP P +L PP PPA P +A R T GP
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPA---SPTLQAPRRP---------PTPGPDTSVSG 561
Query: 512 PR------PAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSP 565
PR P PPP P R P+S S H+ + TS+ G S
Sbjct: 562 PRLTLALAPGPPPPPSRS-----PSSTLSGPDLAGHS-----SSATSTPEELRGYDSGPE 611
Query: 566 AGPVSFPPPPYLARSIDPL--PRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFR 623
G + PPP + P R P+P + P PL P PP++ + G
Sbjct: 612 GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-----PWPPATGPGSADGLCT 666
Query: 624 RPESPRPRVSFPKTPEVGPGPPPGPL-SKAPQPVPPGVGELPARGPRLFDFP 674
E+ P + P + PGP PG KA G + RL + P
Sbjct: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718
Score = 53.5 bits (127), Expect = 2e-06
Identities = 129/559 (23%), Positives = 179/559 (32%), Gaps = 105/559 (18%)
Query: 585 PRPPSPAQNPQDPPLVPLTLALPPA---------------------PPSSCHQNTSGSFR 623
PRPP + P PP+ P L + A P S+ + + R
Sbjct: 27 PRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84
Query: 624 RPESPRPRVSFP-KTPEVGPGPPPGPLSKAPQPVPPG-------VGELPARGPRLFDFPP 675
P S R + P K GP PG S +P P G E ARG + + P
Sbjct: 85 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG-KATEAPK 143
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
P + M + E + P+PP + P S+ S
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203
Query: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP--PLAKFPPPSQPQPP 793
++ + T +PA + A++ P P P A+ P + P
Sbjct: 204 --SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261
Query: 794 PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA 853
P P K L ++ Q R A GPL ++ + PS A P SA
Sbjct: 262 QPKP-------KGLQALRPPQVTPPRKDAAPAL---GPLSSSPLATPSPS---APPSPSA 308
Query: 854 APSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEV 913
PS Q P P A+ SQ +TS G + P P P++P PPP + PPA
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQA-PPAL----- 361
Query: 914 LEEISRACETLVERVGRSATDPADPVDTAEPA--DSGTERLL---------PPAQAKEEA 962
A L A+ P P+ T P ++ LL PP QA
Sbjct: 362 ------ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 963 GGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLD 1022
VS S + S+ P + A P S
Sbjct: 416 PASPPVSPSATPPSQ------------APPSLAAPPLQVPPSPPASPPMSPSA------- 456
Query: 1023 LQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
+ P A PP A P AP A TPP ++P A PG
Sbjct: 457 -----------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA--SFPGQA 503
Query: 1083 GVSRADMLKLRSLSEGPPK 1101
S + L + L+ PP+
Sbjct: 504 PFSPSASLPMSPLATPPPQ 522
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 129 bits (324), Expect = 2e-29
Identities = 150/501 (29%), Positives = 169/501 (33%), Gaps = 158/501 (31%)
Query: 244 LPLPPPPLP----PPPPPPP---------------PPPPPLPGLATSPPFQLTKPGLWST 284
LP PPPPLP PPPPP P PPPPPLPG A PP L PG
Sbjct: 908 LPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL--PGA--- 962
Query: 285 LHGDAWGPERKGSA-PPERQEQRHSLPHPYPYPAPAYTAHPP-GHRLVPAAPPGPG---P 339
G P G+ PP +P P P P PP +P PP PG P
Sbjct: 963 --GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 340 RPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTS 399
PP G P PG+ + P A +P PP LPG
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGI------------PPPPPLPGAGIP----PPPPLPGA--- 1061
Query: 400 SSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL 459
G+ P P +PGA P L P G P P
Sbjct: 1062 ------------GIPPPPPLPGAGIPPPPPL-----------------PGAGIPPPPP-- 1090
Query: 460 SLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPL 519
PG PPPPP P + PPPPP G P PPPL
Sbjct: 1091 --LPGAGIPPPPPLPGVGIPPPPP------------------------LPGAGIPPPPPL 1124
Query: 520 PHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLAR 579
P + PP PP P +G P V PPPP L
Sbjct: 1125 P------------------GAGIPPPPPLP-------GAGIPPPPPLPRVGIPPPPPLPG 1159
Query: 580 SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPE 639
+ P P PP P PP +P + +PP PP G P P P P P
Sbjct: 1160 AGIP-PPPPLPGAGIPPPPPLP-GVGIPPPPP------LPGVGIPPPPPLPGAGIPPPPP 1211
Query: 640 V-GPGPPPGPLSKAPQPVPPGVG-----ELPARGPRLF-----DFPPTPLEDQFEEPAEF 688
+ G G PP P AP PPG G LP GP L PTP F P
Sbjct: 1212 LPGMGIPPAP---APPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPP-- 1266
Query: 689 KILPDGLANIMKMLDESIRKE 709
LP GL + D+ RK+
Sbjct: 1267 --LPSGLFGLGMNQDKGSRKQ 1285
Score = 121 bits (304), Expect = 5e-27
Identities = 170/623 (27%), Positives = 199/623 (31%), Gaps = 198/623 (31%)
Query: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPE------RQEQRHS---- 308
PPPPP L LWS G + GS PP + HS
Sbjct: 810 PPPPPSL---------------LWSA------GQGQPGSQPPHSISTEFQTSHEHSVSSA 848
Query: 309 ------LPHPYPYPAPAYTAHPPGHRLVPAAPPG-PGPRPPGAESHGCLPATRPPGSDLR 361
+P P P P ++ PG +VP PP PG P LP+T P +
Sbjct: 849 FKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVP------TLPSTAIP----Q 898
Query: 362 ESRVQRSRMDSSVSPAATTACVPYAPSRP-------PGLPGTTTSSSSSSSSNTGLRGVE 414
+Q + M P A +P P P P LPG G+
Sbjct: 899 PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGA---------------GIP 943
Query: 415 PNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCP 474
P P +PGA P L P A P L P LP G PPPPP P
Sbjct: 944 PPPPLPGAAIPPPPPL---------PGAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLP 993
Query: 475 RLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS 534
PPPPP G P PPPLP + PP
Sbjct: 994 GAGIPPPPPL------------------------PGAGIPPPPPLPGAG--IPPPPPLPG 1027
Query: 535 VGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNP 594
G PP PP P +G P PPPP L + P P PP P
Sbjct: 1028 AGI-----PPPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGI 1074
Query: 595 QDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVG----PGPPPGPLS 650
PP +P +PP PP G+ P P P V P P + P PPP P +
Sbjct: 1075 PPPPPLP-GAGIPPPPP------LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGA 1127
Query: 651 KAPQPVP-PGVGELPARG-PRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRK 708
P P P PG G P PR+ PP PL
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG---------------------------- 1159
Query: 709 EEEQQQHEAGVAPQPPLKEPFASLQSPFP---TDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
AG+ P PPL P A + P P P P V +
Sbjct: 1160 --------AGIPPPPPL--PGAGIPPPPPLPGVGIPPPPPLPGVGIPP------------ 1197
Query: 766 EEEKKPPP----ALPPPPPLAKFPPPSQPQPPPPPP----PSPASLLKSLASVLEGQKYC 817
PPP +PPPPPL P P PP PPP P P L S +L
Sbjct: 1198 -----PPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSS 1252
Query: 818 YRGTGAAVSTRPGPLPTTQYSPG 840
T P PLP+ + G
Sbjct: 1253 TLPTPQVCGFLPPPLPSGLFGLG 1275
Score = 121 bits (303), Expect = 7e-27
Identities = 157/529 (29%), Positives = 178/529 (33%), Gaps = 153/529 (28%)
Query: 205 VVQPVPPAAL--SGPSGEEGLSP----------------GGKRRRGCN---------SEQ 237
+ QP PP +L S G+ G P + CN +E
Sbjct: 807 ISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
Query: 238 TGLPPGLPLPPPPLPPPP----PPPP----PPPPPLPGLATSPPFQLTKPGLWSTLHGDA 289
+ PGL + PPP PP P P P P PPPL G PP PG
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG--------- 917
Query: 290 WGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPP-GHRLVPAAPPGPG---PRPPGAE 345
G PP LP P P P PP +P PP PG P PP
Sbjct: 918 -----AGIPPPPPLPGAGILPLP-PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Query: 346 SHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSS 405
G P PG+ + P A +P PP LPG
Sbjct: 972 GAGIPPPPPLPGAGI------------PPPPPLPGAGIP----PPPPLPGA--------- 1006
Query: 406 SNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGP 465
G+ P P +PGA P L P A P L P L PG
Sbjct: 1007 ------GIPPPPPLPGAGIPPPPPL---------PGAGIPPPPPLPGAGIPPPPPL-PGA 1050
Query: 466 SSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPR------PAPPPL 519
PPPPP P PPPPP L G G PP P PPPL
Sbjct: 1051 GIPPPPPLPGAGIPPPPP--LPGA-----------------GIPPPPPLPGAGIPPPPPL 1091
Query: 520 PHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLAR 579
P + PP VG PP PP P +G P PPPP L
Sbjct: 1092 P--GAGIPPPPPLPGVG-----IPPPPPLP-------GAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 580 SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPE 639
+ P P PP P PP +P +PP PP G+ P P P V P P
Sbjct: 1138 AGIP-PPPPLPRVGIPPPPPLP-GAGIPPPPP------LPGAGIPPPPPLPGVGIPPPPP 1189
Query: 640 VGPG---PPPGPLSKA---PQPVPPGVGELPARGPRL----FDFPPTPL 678
+ PG PPP PL A P P PG+G PA P L PP PL
Sbjct: 1190 L-PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPL 1237
Score = 116 bits (290), Expect = 2e-25
Identities = 173/632 (27%), Positives = 201/632 (31%), Gaps = 211/632 (33%)
Query: 335 PGPGPRPPGAES----HGC----------------------------------------- 349
PG P PPGAES C
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQG 823
Query: 350 LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409
P ++PP S E + + SVS A +C PS PP LP T SSSS G
Sbjct: 824 QPGSQPPHSISTEFQTSH---EHSVSSAFKNSC--NIPS-PPPLPCT-----ESSSSMPG 872
Query: 410 LRGV-EPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSP 468
L V P P +PG P+ + P + P P +PP P P
Sbjct: 873 LGMVPPPPPPLPGMTVPTLPSTAIPQ-----PPPLQGTEMLPPPPPPLPGAGIPPPPPLP 927
Query: 469 -----PPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHRE 523
P PP P PPPPP L G A P PPPLP
Sbjct: 928 GAGILPLPPLPGAGIPPPPP--LPGAAI----------------------PPPPPLPGAG 963
Query: 524 GFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP 583
L PP + PP PP P +G P PPPP L + P
Sbjct: 964 IPLPPPLPGAGI-------PPPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIP 1009
Query: 584 LPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG 643
P PP P PP +P +PP PP G+ P P P P P + PG
Sbjct: 1010 -PPPPLPGAGIPPPPPLP-GAGIPPPPP------LPGAGIPPPPPLPGAGIPPPPPL-PG 1060
Query: 644 ---PPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMK 700
PPP PL A P PP LP G PP PL P P L +
Sbjct: 1061 AGIPPPPPLPGAGIPPPP---PLPGAGIP----PPPPLPGAGIPP------PPPLPGV-- 1105
Query: 701 MLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTT 760
G+ P PPL P A + P P A P +
Sbjct: 1106 -----------------GIPPPPPL--PGAGIPPPPPLPGAGIPPPPPL----------- 1135
Query: 761 TTATQEEEKKPPPALPPPPPLAKF----PPPSQPQPPPPPPPSPASLLKSLASVLEGQKY 816
P +PPPPPL + PPP PPPPP P
Sbjct: 1136 ----------PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLP---------------- 1169
Query: 817 CYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGG 876
GA + P PLP P PP +PP P A G P P +
Sbjct: 1170 -----GAGIPP-PPPLPGVGIPPPPPLPGVGIPPPPPLPGA-GIPPPPPLPGMGIPPAPA 1222
Query: 877 PWARERRAGEEPVPGPMTPTQPPP--PLSLPP 906
P P+P P T PPP P+S PP
Sbjct: 1223 P----------PLPPPGTGIPPPPLLPVSGPP 1244
Score = 105 bits (262), Expect = 4e-22
Identities = 139/496 (28%), Positives = 167/496 (33%), Gaps = 123/496 (24%)
Query: 459 LSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPP 518
L+LPP P PPCP P + + + + + T+ +P PPP
Sbjct: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814
Query: 519 LPHREGFLGPPASR----FSVGTQDSH-------------TPPTPPTPTTSSSNSNSGSH 561
G P S+ S Q SH P PP P T SS+S G
Sbjct: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG-- 872
Query: 562 SSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGS 621
G V PPPP ++ LP PQ PPL + PP PP G+
Sbjct: 873 ----LGMVPPPPPPLPGMTVPTLP----STAIPQPPPLQGTEMLPPPPPP------LPGA 918
Query: 622 FRRPESPRPR---VSFPKTPEVG-PGPPPGPLSKAPQPVP-PGVG-ELPARGPRLFDFPP 675
P P P + P P G P PPP P + P P P PG G LP P PP
Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
PL P P L AG+ P PPL P A + P
Sbjct: 979 PPLPGAGIPP------PPPLPG-------------------AGIPPPPPL--PGAGIPPP 1011
Query: 736 FPTDTA---PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPP----ALPPPPPL--AKFPP 786
P A P P + PPP +PPPPPL A PP
Sbjct: 1012 PPLPGAGIPPPPPLPGAGI-----------------PPPPPLPGAGIPPPPPLPGAGIPP 1054
Query: 787 PSQ------PQPP-------PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLP 833
P P PP PPPPP P + + + GA + P PLP
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------PGAGIPP-PPPLP 1103
Query: 834 TTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPM 893
P PP +PP P A P P + P R P+PG
Sbjct: 1104 GVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG--IPPPPPLPRVGIPPPPPLPGAG 1161
Query: 894 TPTQPPPPL---SLPP 906
P PPPPL +PP
Sbjct: 1162 IP--PPPPLPGAGIPP 1175
Score = 72.0 bits (175), Expect = 5e-12
Identities = 68/220 (30%), Positives = 79/220 (35%), Gaps = 63/220 (28%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP------P 248
PP+ A PP P+P A + P G G+PP PLP P
Sbjct: 1056 PPLPGAGIPPP-PPLPGAGIPPPPPLPG---------------AGIPPPPPLPGAGIPPP 1099
Query: 249 PPLP----PPPPPPP----PPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300
PPLP PPPPP P PPPPPLPG PP L G+ PP
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----------------PP 1142
Query: 301 ERQEQRHSLPHPYPYPAPAYTAHPP-GHRLVPAAPPGPG---PRPPGAESHGCLPATRPP 356
R +P P P P PP +P PP PG P PP G P P
Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP 1202
Query: 357 GSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGT 396
G+ + P +P AP+ P PGT
Sbjct: 1203 GAGI------------PPPPPLPGMGIPPAPAPPLPPPGT 1230
Score = 53.9 bits (128), Expect = 1e-06
Identities = 88/359 (24%), Positives = 111/359 (30%), Gaps = 90/359 (25%)
Query: 567 GPVSFPPPPYLARSIDPLP-RPPSPA---QNPQDPPLVPLTLALPPAPPSSCHQNTSGSF 622
G ++ PP +D LP RPP P PQ ++L + P S
Sbjct: 753 GVLTLPP-------VDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISV--------- 796
Query: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQF 682
+ +S +P S + P PPP L A Q P PP + +F
Sbjct: 797 -QLDSHQPTQSISQPP-----PPPSLLWSAGQGQPGSQ-------------PPHSISTEF 837
Query: 683 EEPAEFKILPDGLANIMKMLDESIRK--EEEQQQHEAGVAPQPPLKEPFASLQSPFPTDT 740
+ E + N + E G+ P PP P P T
Sbjct: 838 QTSHEHSV-SSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPP---------PPLPGMT 887
Query: 741 APTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLA-----KFPP-PSQPQPPP 794
PT P+ A+ T P +PPPPPL PP P PPP
Sbjct: 888 VPTL--PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPP 945
Query: 795 PP------PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATAL 848
PP PP P G G + P PLP P PP +
Sbjct: 946 PPLPGAAIPPPPP----------------LPGAGIPL---PPPLPGAGIPPPPPLPGAGI 986
Query: 849 PPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPA 907
PP P A P P +G P P P P+ PPP LP A
Sbjct: 987 PPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039
Score = 43.1 bits (100), Expect = 0.002
Identities = 82/370 (22%), Positives = 120/370 (32%), Gaps = 64/370 (17%)
Query: 141 AELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNL---------LHLEHKRNYGAK 191
A+ G R +++FH+ + Q +L ++Q L L L+ ++
Sbjct: 169 AQDGQRTSSGSDTDIYSFHSATEQE--DLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQL 226
Query: 192 RGGPPVKRAAEPPVVQPVPPAALS------GPSGEEGLSPGGKRRRGCNSEQTGLPPGLP 245
+G + AA P V P P A L GPSG G +PG S + LP L
Sbjct: 227 QGAE--EPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284
Query: 246 LPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPER--- 302
P PP P P P L + P P + +A GP + + P R
Sbjct: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEA-GPGEEAAGAPVRGAG 343
Query: 303 -------QEQRHSLPHPYP---------YPAPAYTAHPPGHRL----VPAAPPGPGPRPP 342
++ P P AP P PAA PG P
Sbjct: 344 DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAP 403
Query: 343 GAESHGCLPATRP----------------PGSDLRESRVQRSRMDSSVSPAATTACVPY- 385
P P P +S + R + S+S + TA
Sbjct: 404 SQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVA 463
Query: 386 APSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSS 445
AP++ G + S S+ T G P + G+ H + G + P+ +
Sbjct: 464 APAKKHRADGGLAAGLSRSADWTEELGAR-TPRVGGSAHLLERGVASDSGGGVSPALAAK 522
Query: 446 RKPFLGAPAA 455
GAPAA
Sbjct: 523 AS---GAPAA 529
Score = 35.8 bits (81), Expect = 0.36
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 20/81 (24%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGL--PLPPPP-- 250
PP+ PP P+P A + P G+ G+PP PLPPP
Sbjct: 1188 PPLPGVGIPPP-PPLPGAGIPPPPPLPGM---------------GIPPAPAPPLPPPGTG 1231
Query: 251 LPPPPPPPPPPPPPLPGLATS 271
+PPPP P PP LP + +S
Sbjct: 1232 IPPPPLLPVSGPPLLPQVGSS 1252
Score = 33.5 bits (75), Expect = 1.8
Identities = 54/232 (23%), Positives = 77/232 (33%), Gaps = 34/232 (14%)
Query: 768 EKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYC---YRGTG-- 822
E + P P P L PS P P SP+S G++ RG G
Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
Query: 823 ------AAVSTRPGPLPTTQYSP-------------------GPPSGATALPPTSAAPSA 857
A P P +++P GP + A A P S APS
Sbjct: 346 DEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQ 405
Query: 858 Q-GSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEE 916
+ P P + +T+ + + P P +P P LS + + V
Sbjct: 406 RCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465
Query: 917 IS--RACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVA 966
RA L + RSA D + + P G+ LL A + GGV+
Sbjct: 466 AKKHRADGGLAAGLSRSA-DWTEELGARTPRVGGSAHLLERGVASDSGGGVS 516
Score = 33.1 bits (74), Expect = 2.3
Identities = 24/59 (40%), Positives = 26/59 (44%), Gaps = 10/59 (16%)
Query: 33 PHPPPRSAWLPGGRCSASIGQPPLPA---PLPPSHGSSSGHPSKPYYAPGAPTPRPLHG 88
P PPP LPG +A PPLP PLPP + P P G P P PL G
Sbjct: 943 PPPPP----LPG---AAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPG 994
Score = 32.0 bits (71), Expect = 5.2
Identities = 18/42 (42%), Positives = 19/42 (45%), Gaps = 16/42 (38%)
Query: 241 PPGLPLPPPPLPPPPPPP----------PPP------PPPLP 266
PPG +PPPPL P PP P P PPPLP
Sbjct: 1227 PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 31.6 bits (70), Expect = 6.8
Identities = 37/130 (28%), Positives = 46/130 (35%), Gaps = 24/130 (18%)
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844
P S QPPPPP SLL S G G S P + T + S
Sbjct: 803 PTQSISQPPPPP-----SLLWSA------------GQGQPGSQPPHSISTEFQTSHEHSV 845
Query: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSL 904
++A + PS P P SSS P P+PG PT P +
Sbjct: 846 SSAFKNSCNIPSPP--PLPCTESSSSM-----PGLGMVPPPPPPLPGMTVPTLPSTAIPQ 898
Query: 905 PPARSESEVL 914
PP +E+L
Sbjct: 899 PPPLQGTEML 908
Score = 31.6 bits (70), Expect = 6.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 5/57 (8%)
Query: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHG 88
PP PP A +P +G PP P PLP + P P G P P PL G
Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPP-PPPLP----GAGIPPPPPLPGAGIPPPPPLPG 1137
Score = 31.2 bits (69), Expect = 8.9
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 5/57 (8%)
Query: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHG 88
PP PP A +P +G PP P PLP + P P G P P PL G
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPP-PPPLP----GAGIPPPPPLPGAGIPPPPPLPG 1181
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 129 bits (324), Expect = 2e-29
Identities = 207/822 (25%), Positives = 284/822 (34%), Gaps = 153/822 (18%)
Query: 224 SPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWS 283
SPG +S P P PPPL PP P PP P P + P +T G +
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 284 TLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPA---YTAHPPGHRLVPAAPPGPGPR 340
+ R APP PHP YP + P G + AA GP
Sbjct: 197 PMEPPT---SRMFQAPPGAPP-----PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 341 ----------PPGAESHGC--LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPS 388
P S G P T+PP + V + S+ PA P P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTP-----VGGGNLPSAPPPANFPHVTPNLPP 303
Query: 389 RPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKP 448
P P +++S+S GL G +P PG H +P G L P P
Sbjct: 304 PPALRP-----LNNASASPPGL-GAQPLPG-----HLPSPHAMGQGMGGLPPGPEKG--P 350
Query: 449 FLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGT 508
L A +PH SLPP SS P PP +R P + A ++ F
Sbjct: 351 TL---APSPH-SLPPASSSAPAPP----MRFPYSSSSSSSAAASSSSSSSSSSASPF--- 399
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P A P PH PP + SV Q PP T S S + P
Sbjct: 400 --PASQALPSYPHSF----PPPTSLSVSNQ-------PPKYTQPSLPSQAVWSQGPP--- 443
Query: 569 VSFPPPPY---LARS-IDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR 624
PPPPY LA S P P PPS + A PP H ++
Sbjct: 444 ---PPPPYGRLLANSNAHPGPFPPSTGAQ---------STAHPPVSTHHHHHQQQQQQQQ 491
Query: 625 PESPRPRVSFPKTPEVGPGPP---PGPLSKA------PQPVPPGVGELPARGPRLFDFPP 675
+ + + GP PP P PL P + P +G L P PP
Sbjct: 492 QQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP 551
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
+ + + P+G + S Q + P + P + P
Sbjct: 552 PHSQVSYSQAG-----PNG-----PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGA---P 598
Query: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
+P PT T + ++T T ++ A + P P PP + P P + P
Sbjct: 599 YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP----PPYGKRAPSPGAYKTATP 654
Query: 796 PPPSPASLLKSLASVLEGQKYCYRGTG----------AAVSTRPGPLPTTQYSPGPPSGA 845
P P S S G YRGT + + PGPLP P PSG
Sbjct: 655 PGYKPGSP----PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP-----PAGPSGL 705
Query: 846 TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
+LPP AAP++ P SA+ Q A E E PVP +P+ PP + +P
Sbjct: 706 PSLPPPPAAPAS--GPPLSATQIKQEP------AEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 906 PARSESEVLEEISRACETLVERVGRSATD--PADPVDTAEPADSGTERLLPPAQ--AKEE 961
S+S ++ + RS P + A+ E++ A+ A+EE
Sbjct: 758 SHASQSA---RFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
Query: 962 AGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRA 1003
+ R++E +KE R + + + +EGRA
Sbjct: 815 KE---------REREREREKEREREKERELERSVKLAQEGRA 847
Score = 92.4 bits (228), Expect = 3e-18
Identities = 168/733 (22%), Positives = 235/733 (32%), Gaps = 144/733 (19%)
Query: 77 APGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRY 136
+P +P + +S G Q R P L+ Q +S EA+ H ++
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTP 191
Query: 137 GGSFAELGPRIGRLQQA---------QLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRN 187
G A + P R+ QA QL+ TG + P K
Sbjct: 192 TGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP-------------KGG 238
Query: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP 247
A G P PP P+ ++ SG SG P G N P P
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSS-SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV 297
Query: 248 PPPLPPPP-------------------------------------PPPP-------PPPP 263
P LPPPP PP P P P
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 264 PLPGLATSPP-----FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPA- 317
LP ++S P F + S + ++P + S PH +P P
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 318 -------PAYT---------------AHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRP 355
P YT PP RL+ + PGP PP S G P
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP---STGAQSTAHP 474
Query: 356 PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP-------GLPGTTTSSSSSSSSNT 408
P S Q+ + + S PP L G ++ + + +
Sbjct: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
Query: 409 GLRGVEPNPGIPGADHYQTPALEVSHH--GRLGPSAHSSRKPFLGAPAATPHLSLPPGPS 466
L + P P PG H P +VS+ G GP SS + ++T S P
Sbjct: 535 SLGSLRPYP--PGPAHLPPPHSQVSYSQAGPNGPPVSSSS----NSSSSTSQGSYPCSHP 588
Query: 467 SPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFL 526
SP P PP P A + + T P P PPP R
Sbjct: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP--PGPPPYGKR---- 642
Query: 527 GPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPR 586
P + T + P +PP+ T + G +S PAGP +F P + ++ P P
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG--TSPPAGPGTFKPG---SPTVGPGPL 697
Query: 587 PPS-PAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPP 645
PP+ P+ P PP + PP + Q + + PESP P P P PP
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP-------PARSPSPP 750
Query: 646 PGPLSKAPQPVPPGVGELPARGPRLFD--FPPTPLEDQFEEPAEFKILPDGLANIMKMLD 703
P + P AR + D F D + P E L A+++
Sbjct: 751 PKVVD------VPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLV---- 800
Query: 704 ESIRKEEEQQQHE 716
E +R+E EQ+ E
Sbjct: 801 EKVRREAEQRARE 813
Score = 63.9 bits (154), Expect = 1e-09
Identities = 111/463 (23%), Positives = 156/463 (33%), Gaps = 132/463 (28%)
Query: 542 TPPTPPTPTTSSSNSNSGSH-SSSPAGPVSFPPPPYLARSIDP---LPRPPSPAQNPQDP 597
T P+ +P + ++S+S S S PA P + PPP S P PR P + P P
Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPARP--YHPPPLFPPSPQPPDSTPRQPEASFEPH-P 187
Query: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPES---PRPRVSFPKTPEVGPGPPPGP------ 648
+ P P PP TS F+ P P P++ T V GPP GP
Sbjct: 188 SVTPTGYHAPMEPP------TSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241
Query: 649 -------------------------LSKAPQPVPP----GVGELPARGPRLF------DF 673
S AP PP G G LP+ P +
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301
Query: 674 PPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQP---------P 724
PP P + P GL + L + Q G+ P P P
Sbjct: 302 PPPPALRPLNNAS---ASPPGLG--AQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356
Query: 725 LKEPFASLQSP-----FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP 779
P AS +P FP ++ +++A A + +++++++ + + P + PPP
Sbjct: 357 HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416
Query: 780 PLA------KFPPPSQP------QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVST 827
L+ K+ PS P Q PPPPPP L S +
Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANS-------------------NA 457
Query: 828 RPGPLPTTQYSPGPPSGATALPPTSA-------APSAQGSPQPSASSSSQFSTSGG---- 876
PGP P P + +TA PP S Q Q Q + G
Sbjct: 458 HPGPFP-----PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 877 ---PWARERRAGEEPVPGPMTPT------QPPPPLSLPPARSE 910
P E + P M+P+ PP P LPP S+
Sbjct: 513 GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQ 555
Score = 55.5 bits (132), Expect = 4e-07
Identities = 121/516 (23%), Positives = 156/516 (30%), Gaps = 114/516 (22%)
Query: 33 PHPPPRSAWLPGGRCSAS---IGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGK 89
P+ PP A P SAS +G PLP LP H G P PT P
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP---- 354
Query: 90 LESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFA------EL 143
S H A PA P + S S ++ SA + S A
Sbjct: 355 --SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 144 GPRIGRLQQAQLWNFHTGSCQHRA---KVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRA 200
P Q + S +A + PP LL N A G P
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-----ANSNAHPGPFPPSTG 467
Query: 201 AEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPP---- 256
A+ PV S ++++ +Q G PPPP P P
Sbjct: 468 AQSTAHPPV-----STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGG 522
Query: 257 ------------------PPPPPPPPLPGLATSPPFQLTKP-GLWSTLHGDAWGPERKGS 297
P PP P LP + + P G + ++ +GS
Sbjct: 523 SSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 298 AP---PERQEQRHSLPHPYPYPAPAYT--------------AHPPGHRLVPAAPPGPGPR 340
P P + P+P+P P P T + P G++ A+PPGP P
Sbjct: 583 YPCSHPSPSQGPQGAPYPFP-PVPTVTTSSATLSTVIATVASSPAGYK--TASPPGPPPY 639
Query: 341 PPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSS 400
A S G PPG Y P PP
Sbjct: 640 GKRAPSPGAYKTATPPG---------------------------YKPGSPP--------- 663
Query: 401 SSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS 460
S + + G RG P P PG +P + GPS S P APA+ P LS
Sbjct: 664 SFRTGTPPGYRGTSP-PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLS 722
Query: 461 L------PPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P P P P P PPP + P+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758
Score = 47.8 bits (112), Expect = 9e-05
Identities = 96/412 (23%), Positives = 133/412 (32%), Gaps = 96/412 (23%)
Query: 22 LSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAP 81
L WS PP PPP L P P PPS G+ S
Sbjct: 432 LPSQAVWSQGPPPPPPYGRLLANSNAH--------PGPFPPSTGAQS------------- 470
Query: 82 TPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFA 141
H + + H Q ++ Q +Q Q + H GGS
Sbjct: 471 ---TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL--EGGSSH 525
Query: 142 ELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYG-AKRGGPPVKRA 200
P L + G A + PP QV +Y A GPPV +
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQV----------SYSQAGPNGPPVSSS 571
Query: 201 AEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP 260
+ S PS +G P G P P PP+P
Sbjct: 572 SNSSSSTSQGSYPCSHPSPSQG------------------PQGAPYPFPPVPTVTTSSAT 613
Query: 261 PPPPLPGLATSPP-FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY-PYPAP 318
+ +A+SP ++ P GP G P + + P Y P P
Sbjct: 614 LSTVIATVASSPAGYKTASPP----------GPPPYGKRAPSPGAYKTATPPGYKPGSPP 663
Query: 319 AY-TAHPPGHR--LVPAAP---------PGPGPRPPGAESHGCLPATRPP------GSDL 360
++ T PPG+R PA P GPGP PP S LP+ PP G L
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG--LPSLPPPPAAPASGPPL 721
Query: 361 RESRVQRSRMDSSVSPAATTACVPYA--PSRPPGLPGTTTSSSSSSSSNTGL 410
+++++ + +P + VP A PS PP + + +S S+ N L
Sbjct: 722 SATQIKQEPAEEYETPESP---VPPARSPSPPPKVVDVPSHASQSARFNKHL 770
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/195 (24%), Positives = 65/195 (33%), Gaps = 15/195 (7%)
Query: 721 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
P+P SL D + +T+ + + + E + L P
Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPA 156
Query: 781 LAKFPPPSQPQPPPPP---PPSPASLLKSLASVLEGQKYC--YRGTGAAVSTRPG-PLPT 834
PPP P P PP P P + + SV + T PG P P
Sbjct: 157 RPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216
Query: 835 TQYSPGPPSGATALPPT----SAAPSAQGSP-----QPSASSSSQFSTSGGPWARERRAG 885
Q PG G + PP A S+ G P P ++ S+SG A +
Sbjct: 217 PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276
Query: 886 EEPVPGPMTPTQPPP 900
PV G P+ PPP
Sbjct: 277 TTPVGGGNLPSAPPP 291
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 129 bits (324), Expect = 2e-29
Identities = 207/822 (25%), Positives = 284/822 (34%), Gaps = 153/822 (18%)
Query: 224 SPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWS 283
SPG +S P P PPPL PP P PP P P + P +T G +
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
Query: 284 TLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPA---YTAHPPGHRLVPAAPPGPGPR 340
+ R APP PHP YP + P G + AA GP
Sbjct: 197 PMEPPT---SRMFQAPPGAPP-----PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 341 ----------PPGAESHGC--LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPS 388
P S G P T+PP + V + S+ PA P P
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTP-----VGGGNLPSAPPPANFPHVTPNLPP 303
Query: 389 RPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKP 448
P P +++S+S GL G +P PG H +P G L P P
Sbjct: 304 PPALRP-----LNNASASPPGL-GAQPLPG-----HLPSPHAMGQGMGGLPPGPEKG--P 350
Query: 449 FLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGT 508
L A +PH SLPP SS P PP +R P + A ++ F
Sbjct: 351 TL---APSPH-SLPPASSSAPAPP----MRFPYSSSSSSSAAASSSSSSSSSSASPF--- 399
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P A P PH PP + SV Q PP T S S + P
Sbjct: 400 --PASQALPSYPHSF----PPPTSLSVSNQ-------PPKYTQPSLPSQAVWSQGPP--- 443
Query: 569 VSFPPPPY---LARS-IDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR 624
PPPPY LA S P P PPS + A PP H ++
Sbjct: 444 ---PPPPYGRLLANSNAHPGPFPPSTGAQ---------STAHPPVSTHHHHHQQQQQQQQ 491
Query: 625 PESPRPRVSFPKTPEVGPGPP---PGPLSKA------PQPVPPGVGELPARGPRLFDFPP 675
+ + + GP PP P PL P + P +G L P PP
Sbjct: 492 QQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP 551
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
+ + + P+G + S Q + P + P + P
Sbjct: 552 PHSQVSYSQAG-----PNG-----PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGA---P 598
Query: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
+P PT T + ++T T ++ A + P P PP + P P + P
Sbjct: 599 YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP----PPYGKRAPSPGAYKTATP 654
Query: 796 PPPSPASLLKSLASVLEGQKYCYRGTG----------AAVSTRPGPLPTTQYSPGPPSGA 845
P P S S G YRGT + + PGPLP P PSG
Sbjct: 655 PGYKPGSP----PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP-----PAGPSGL 705
Query: 846 TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
+LPP AAP++ P SA+ Q A E E PVP +P+ PP + +P
Sbjct: 706 PSLPPPPAAPAS--GPPLSATQIKQEP------AEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 906 PARSESEVLEEISRACETLVERVGRSATD--PADPVDTAEPADSGTERLLPPAQ--AKEE 961
S+S ++ + RS P + A+ E++ A+ A+EE
Sbjct: 758 SHASQSA---RFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
Query: 962 AGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRA 1003
+ R++E +KE R + + + +EGRA
Sbjct: 815 KE---------REREREREKEREREKERELERSVKLAQEGRA 847
Score = 92.4 bits (228), Expect = 3e-18
Identities = 168/733 (22%), Positives = 235/733 (32%), Gaps = 144/733 (19%)
Query: 77 APGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRY 136
+P +P + +S G Q R P L+ Q +S EA+ H ++
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTP 191
Query: 137 GGSFAELGPRIGRLQQA---------QLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRN 187
G A + P R+ QA QL+ TG + P K
Sbjct: 192 TGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP-------------KGG 238
Query: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP 247
A G P PP P+ ++ SG SG P G N P P
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSS-SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV 297
Query: 248 PPPLPPPP-------------------------------------PPPP-------PPPP 263
P LPPPP PP P P P
Sbjct: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 264 PLPGLATSPP-----FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPA- 317
LP ++S P F + S + ++P + S PH +P P
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 318 -------PAYT---------------AHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRP 355
P YT PP RL+ + PGP PP S G P
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP---STGAQSTAHP 474
Query: 356 PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP-------GLPGTTTSSSSSSSSNT 408
P S Q+ + + S PP L G ++ + + +
Sbjct: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
Query: 409 GLRGVEPNPGIPGADHYQTPALEVSHH--GRLGPSAHSSRKPFLGAPAATPHLSLPPGPS 466
L + P P PG H P +VS+ G GP SS + ++T S P
Sbjct: 535 SLGSLRPYP--PGPAHLPPPHSQVSYSQAGPNGPPVSSSS----NSSSSTSQGSYPCSHP 588
Query: 467 SPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFL 526
SP P PP P A + + T P P PPP R
Sbjct: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP--PGPPPYGKR---- 642
Query: 527 GPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPR 586
P + T + P +PP+ T + G +S PAGP +F P + ++ P P
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRG--TSPPAGPGTFKPG---SPTVGPGPL 697
Query: 587 PPS-PAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPP 645
PP+ P+ P PP + PP + Q + + PESP P P P PP
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP-------PARSPSPP 750
Query: 646 PGPLSKAPQPVPPGVGELPARGPRLFD--FPPTPLEDQFEEPAEFKILPDGLANIMKMLD 703
P + P AR + D F D + P E L A+++
Sbjct: 751 PKVVD------VPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLV---- 800
Query: 704 ESIRKEEEQQQHE 716
E +R+E EQ+ E
Sbjct: 801 EKVRREAEQRARE 813
Score = 63.9 bits (154), Expect = 1e-09
Identities = 111/463 (23%), Positives = 156/463 (33%), Gaps = 132/463 (28%)
Query: 542 TPPTPPTPTTSSSNSNSGSH-SSSPAGPVSFPPPPYLARSIDP---LPRPPSPAQNPQDP 597
T P+ +P + ++S+S S S PA P + PPP S P PR P + P P
Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPARP--YHPPPLFPPSPQPPDSTPRQPEASFEPH-P 187
Query: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPES---PRPRVSFPKTPEVGPGPPPGP------ 648
+ P P PP TS F+ P P P++ T V GPP GP
Sbjct: 188 SVTPTGYHAPMEPP------TSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAA 241
Query: 649 -------------------------LSKAPQPVPP----GVGELPARGPRLF------DF 673
S AP PP G G LP+ P +
Sbjct: 242 SSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301
Query: 674 PPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQP---------P 724
PP P + P GL + L + Q G+ P P P
Sbjct: 302 PPPPALRPLNNAS---ASPPGLG--AQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP 356
Query: 725 LKEPFASLQSP-----FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP 779
P AS +P FP ++ +++A A + +++++++ + + P + PPP
Sbjct: 357 HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT 416
Query: 780 PLA------KFPPPSQP------QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVST 827
L+ K+ PS P Q PPPPPP L S +
Sbjct: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANS-------------------NA 457
Query: 828 RPGPLPTTQYSPGPPSGATALPPTSA-------APSAQGSPQPSASSSSQFSTSGG---- 876
PGP P P + +TA PP S Q Q Q + G
Sbjct: 458 HPGPFP-----PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP 512
Query: 877 ---PWARERRAGEEPVPGPMTPT------QPPPPLSLPPARSE 910
P E + P M+P+ PP P LPP S+
Sbjct: 513 GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQ 555
Score = 55.5 bits (132), Expect = 4e-07
Identities = 121/516 (23%), Positives = 156/516 (30%), Gaps = 114/516 (22%)
Query: 33 PHPPPRSAWLPGGRCSAS---IGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGK 89
P+ PP A P SAS +G PLP LP H G P PT P
Sbjct: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP---- 354
Query: 90 LESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFA------EL 143
S H A PA P + S S ++ SA + S A
Sbjct: 355 --SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 144 GPRIGRLQQAQLWNFHTGSCQHRA---KVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRA 200
P Q + S +A + PP LL N A G P
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLL-----ANSNAHPGPFPPSTG 467
Query: 201 AEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPP---- 256
A+ PV S ++++ +Q G PPPP P P
Sbjct: 468 AQSTAHPPV-----STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGG 522
Query: 257 ------------------PPPPPPPPLPGLATSPPFQLTKP-GLWSTLHGDAWGPERKGS 297
P PP P LP + + P G + ++ +GS
Sbjct: 523 SSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 298 AP---PERQEQRHSLPHPYPYPAPAYT--------------AHPPGHRLVPAAPPGPGPR 340
P P + P+P+P P P T + P G++ A+PPGP P
Sbjct: 583 YPCSHPSPSQGPQGAPYPFP-PVPTVTTSSATLSTVIATVASSPAGYK--TASPPGPPPY 639
Query: 341 PPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSS 400
A S G PPG Y P PP
Sbjct: 640 GKRAPSPGAYKTATPPG---------------------------YKPGSPP--------- 663
Query: 401 SSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS 460
S + + G RG P P PG +P + GPS S P APA+ P LS
Sbjct: 664 SFRTGTPPGYRGTSP-PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLS 722
Query: 461 L------PPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P P P P P PPP + P+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758
Score = 47.8 bits (112), Expect = 9e-05
Identities = 96/412 (23%), Positives = 133/412 (32%), Gaps = 96/412 (23%)
Query: 22 LSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAP 81
L WS PP PPP L P P PPS G+ S
Sbjct: 432 LPSQAVWSQGPPPPPPYGRLLANSNAH--------PGPFPPSTGAQS------------- 470
Query: 82 TPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFA 141
H + + H Q ++ Q +Q Q + H GGS
Sbjct: 471 ---TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL--EGGSSH 525
Query: 142 ELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYG-AKRGGPPVKRA 200
P L + G A + PP QV +Y A GPPV +
Sbjct: 526 HAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQV----------SYSQAGPNGPPVSSS 571
Query: 201 AEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP 260
+ S PS +G P G P P PP+P
Sbjct: 572 SNSSSSTSQGSYPCSHPSPSQG------------------PQGAPYPFPPVPTVTTSSAT 613
Query: 261 PPPPLPGLATSPP-FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY-PYPAP 318
+ +A+SP ++ P GP G P + + P Y P P
Sbjct: 614 LSTVIATVASSPAGYKTASPP----------GPPPYGKRAPSPGAYKTATPPGYKPGSPP 663
Query: 319 AY-TAHPPGHR--LVPAAP---------PGPGPRPPGAESHGCLPATRPP------GSDL 360
++ T PPG+R PA P GPGP PP S LP+ PP G L
Sbjct: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG--LPSLPPPPAAPASGPPL 721
Query: 361 RESRVQRSRMDSSVSPAATTACVPYA--PSRPPGLPGTTTSSSSSSSSNTGL 410
+++++ + +P + VP A PS PP + + +S S+ N L
Sbjct: 722 SATQIKQEPAEEYETPESP---VPPARSPSPPPKVVDVPSHASQSARFNKHL 770
Score = 42.0 bits (97), Expect = 0.005
Identities = 47/195 (24%), Positives = 65/195 (33%), Gaps = 15/195 (7%)
Query: 721 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
P+P SL D + +T+ + + + E + L P
Sbjct: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPA 156
Query: 781 LAKFPPPSQPQPPPPP---PPSPASLLKSLASVLEGQKYC--YRGTGAAVSTRPG-PLPT 834
PPP P P PP P P + + SV + T PG P P
Sbjct: 157 RPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216
Query: 835 TQYSPGPPSGATALPPT----SAAPSAQGSP-----QPSASSSSQFSTSGGPWARERRAG 885
Q PG G + PP A S+ G P P ++ S+SG A +
Sbjct: 217 PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276
Query: 886 EEPVPGPMTPTQPPP 900
PV G P+ PPP
Sbjct: 277 TTPVGGGNLPSAPPP 291
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 126 bits (317), Expect = 2e-28
Identities = 207/761 (27%), Positives = 254/761 (33%), Gaps = 152/761 (19%)
Query: 242 PGLPLPPPPLPPPPPPPPPPPPPLP---------GLATSPPFQLTKPGLWSTLHGDAWGP 292
P P P PP P PPPP P G P G+ G A P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-----GGATIP 71
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPA 352
E A P R S PA A G R PA PGP S G
Sbjct: 72 ESAPRAGPTRSAGTSS-----RNPASRPPASGRGERAPPAKNTSPGP----VSSPGRASG 122
Query: 353 TRPPG----SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSS 405
T PG LR E V R + + +A +A S P PGT + + + S
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP--TPGTPSPAMARRS 180
Query: 406 SNTGLRGVEPNPG-----IPGADHYQTPALEVSHHGRLGPSAHSSRKPFLG--------- 451
G P P P + + S H PS + R+P G
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 452 --APAATPHLSLP--PGPSSPPPPPCPRLLRPPPPPAW--LKGPACRAARED-GEILEEL 504
+ +ATP LS P GPS+ P P P P L+ P R+D L L
Sbjct: 241 SLSSSATP-LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 505 FFGTEGPPRP-------APPPL---PHREGF---------LGPPASRFSVGTQDSHTPP- 544
P P APP L PH L PP+ Q +PP
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 545 TPPTPTTSSSNSNS--GSHS---SSPAGPVSFPP---PPYLARSIDPLPRPPSPAQNPQD 596
TPP+ T+S S + +HS S P P++ PP PP LA + PL PPSP P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LPPLQAPPSP---PAS 414
Query: 597 PPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPV 656
PPL PL P AP + F P P P V P +P PP P + P
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPA--SPPVSPSATPPSQA 470
Query: 657 PPGVGELPARGPRLFDFPPT--PLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQ 714
PP + P + P PP P+ P + P LA L K Q
Sbjct: 471 PPSLAAPPLQVP---PSPPASPPMSPSATPPPQ---APPPLAAPPLQL----AKPPPQAP 520
Query: 715 HEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPP 772
P L P AS Q+PF +P+ + P + T A + P
Sbjct: 521 PALATPPLQALPSPPASFPGQAPF----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 773 PALPPPPPLAKFPPPSQPQ-------------PPPPPPPSPASLLKSLASVLEGQKYCYR 819
P P + PP P P PPPPPS +S +S L G
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS-----RSPSSTLSGPDL--- 628
Query: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA--------------AP-----SAQGS 860
G + S P Y GP GA A PP A AP A G+
Sbjct: 629 -AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 687
Query: 861 PQPSASSSSQFSTSGGPWARERRAGEE--PVPGPMTPTQPP 899
P P ++ S G E E P PG + P P
Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 113 bits (283), Expect = 1e-24
Identities = 184/684 (26%), Positives = 239/684 (34%), Gaps = 107/684 (15%)
Query: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258
+A E P + A SG +P R S G GLP P P P
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR--RSRAAGTEVGLPRPA----PSARPR 199
Query: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAP 318
PP P ++++ T+P + A G +R R P +P
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-------GLQRPASRSLSSSATPLSSP 252
Query: 319 AYTAHPPGHRLVPAAPPGPG-PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
A + P R P AP P P+P G L A RPP + S SP
Sbjct: 253 ARSG--PSARGTPRAPAHPSQPKPKG------LQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 378 ATTACVPYAPSR-PPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT----PALEV 432
AT + S+ PP LP T SSS + T L P+P P + QT PA
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS--LQTLPSPPATPP 362
Query: 433 SH-HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPAC 491
S LG + FL +P +P L+ PP P +PP P L PP PPA P
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSP-LATPP-PQAPPALALPPLQAPPSPPA--SPPLS 418
Query: 492 RAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTT 551
A + L P +PPP P + PPAS PP P+ T
Sbjct: 419 PLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPAS-----------PPVSPSATP 466
Query: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP--- 608
S + S A P+ PP P + + P PP A P P PL LA PP
Sbjct: 467 PSQ-----APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQLAKPPPQA 519
Query: 609 -----APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP-QPVPPGVGE 662
PP + SF P S P +P P P P+ AP VPP
Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 579
Query: 663 LPA-RGPRLFDFPPTPLED-QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVA 720
P + PR PPTP D P L G
Sbjct: 580 SPTLQAPRR---PPTPGPDTSVSGPRLTLALAPG-------------------------P 611
Query: 721 PQPPLKEPFASLQSP-FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP--- 776
P PP + P ++L P ++ T+ P + A+ + + P
Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671
Query: 777 ---PPPPLAKFPPPSQPQP-PPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
P PPLA P P P PP P A L ++ EG + T A + PGP
Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET-EGPE---SATPAPGALDPGPS 727
Query: 833 PTT---QYSPGPPSGATALPPTSA 853
P T + + G +GA++ P A
Sbjct: 728 PGTSGGKAAAGAGAGASSRSPKQA 751
Score = 111 bits (278), Expect = 5e-24
Identities = 197/768 (25%), Positives = 256/768 (33%), Gaps = 152/768 (19%)
Query: 242 PGLPLPPPPLPPPPPPPPPPPP----PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGS 297
PGL P PP P PPPP P G P G+ G A PE
Sbjct: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPR 76
Query: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG 357
A P R S PA A G R PA PGP S G T PG
Sbjct: 77 AGPTRSAGTSSRN-----PASRPPASGRGERAPPAKNTSPGP----VSSPGRASGTTRPG 127
Query: 358 ----SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGL 410
LR E V R + + +A +A S P PGT + + + S G
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGT 185
Query: 411 RGVEPNPGI-----PGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATP---HLSLP 462
P P P + + S H PS + R+P G P LS
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 463 PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHR 522
P S P P P PA P + L+ L PPR P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKG-------LQALRPPQVTPPRKDAAPA--- 295
Query: 523 EGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSID 582
LGP +S +P P+P S+ S + + PA P S LA
Sbjct: 296 ---LGPLSS----------SPLATPSP---SAALQSQAPPTLPATPHSSSLTCQLAT--- 336
Query: 583 PLP-RPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVG 641
PLP PPSP+ PP + TL PPA P S + GS + T
Sbjct: 337 PLPLAPPSPSA----PPSLQ-TLPSPPATPPSQATTSLGS----------PTLQATHSFL 381
Query: 642 PGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKM 701
P PP PL+ P PP + P + P P+P PA + P LA
Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAP------PSP-------PASPPLSP--LATPSPQ 426
Query: 702 LDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP--FPTDTAPTTTAPAVAVTTTTTTTT 759
++ Q P PP++ PF+ SP P+ T P+ P++A
Sbjct: 427 APNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA-------- 476
Query: 760 TTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPP----------------PPPPSPASL 803
PP +PP PP + PP S PP PPP +P +L
Sbjct: 477 -----------PPLQVPPSPPAS--PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Query: 804 LKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQP 863
L + G A + LP + + PP PP AAP Q P P
Sbjct: 524 ATPPLQALPSPPASF--PGQAPFSPSASLPMSPLATPPPQA----PPVLAAPLLQVPPSP 577
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGP-----MTPTQPPPPLSLPPARSESEVLEEIS 918
AS + Q P + V GP + P PPPP P + L S
Sbjct: 578 PASPTLQ-----APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 632
Query: 919 RACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVA 966
+ + E + + P + P D+ P A ++ A +A
Sbjct: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA 680
Score = 91.7 bits (226), Expect = 6e-18
Identities = 193/751 (25%), Positives = 241/751 (32%), Gaps = 151/751 (20%)
Query: 451 GAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--PAWLK--GPACRAAREDGEILEELFF 506
GA A TP + PG +P PP P RPPPP PA L+ G A R+ L E
Sbjct: 11 GAAARTP-AARAPGLLTPRPPGSP---RPPPPVTPAALRVLGAAGAVGRKP---LAERAG 63
Query: 507 GTEGP--PRPAPPPLPHREGFLGP--PASRFSVGTQDSHTPP---TPPTPTTSSSNSNS- 558
G G P AP P R PASR + PP T P P +S ++
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 559 ---------------------GSHSSSP-------------AGPVSFPPPPYLARSIDP- 583
G + +P +GP P P +AR
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
Query: 584 -----LPRPPSPAQNPQDPPLVPLT--------LALPPAPPSSCHQNTSGSFRRPES--- 627
LPR P+P+ P+ P P P+P + + G +RP S
Sbjct: 184 GTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 628 --------------PRPRVSFPKTPEVGPGPPPGPLS--KAPQPVPPGVGELPARGPRLF 671
P R P+ P P P L + PQ PP PA GP
Sbjct: 243 SSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--- 298
Query: 672 DFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFAS 731
+PL P A + ++ +A PL P S
Sbjct: 299 -LSSSPL-----------ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
Query: 732 LQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP---PPALPPP--PPLAKFPP 786
T +P T P+ A TT+ + T AT P P A PPP PP PP
Sbjct: 347 APPSLQTLPSPPATPPSQA--TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 787 PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP--GPPSG 844
Q PP PP SP + S A S P P +SP PP
Sbjct: 405 ---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 845 ATALPPTS-----AAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
+A PP+ AAP Q P P AS S + P A A P+ P Q P
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA-PPLQLAKPPPQAP 520
Query: 900 PPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAK 959
P L+ PP ++ SA+ P P+ T PP QA
Sbjct: 521 PALATPPLQALPSPPASFPGQAP-----FSPSASLPMSPLAT------------PPPQAP 563
Query: 960 EEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSV-GRRPREGRAKAKAKVPKEKSRRVL 1018
Q R SV G R A P L
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 1019 GNLDLQS---------EEIQGREKSRPDLGGASKAKPPTAPAPPSAPAP-SAQPTPPSAS 1068
DL EE++G + S P+ GGA+ + PP A PA S P PP A
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYD-SGPE-GGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 1069 VPGKKAREEAPGPPGVSRADMLKLRSLSEGP 1099
A P G AD L +EGP
Sbjct: 682 RGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
Score = 90.9 bits (224), Expect = 9e-18
Identities = 171/681 (25%), Positives = 226/681 (33%), Gaps = 116/681 (17%)
Query: 36 PPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSG-HPSKPYYAPGAPTPRPLHGKLESLH 94
P RSA G R S P P+P ++G P AP A P G +S+
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 95 GCVQALLREPA-----QPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGR 149
+ EP+ +P L A+R S+ S A GP
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGL---------QRPASRSLSSSATPLSSPARSGPSARG 261
Query: 150 LQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPV 209
+A H ++ P Q + R A GP + P+ P
Sbjct: 262 TPRAPA---------HPSQPKPKGLQALRPPQVTPPRKDAAPALGP----LSSSPLATPS 308
Query: 210 PPAALSGPSGEEGLSPGGKRRRGCN-SEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGL 268
P AAL + + C + L P P PP L P PP PP
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 269 ATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHR 328
SP Q T L S P + PP + +LP P+P A PP
Sbjct: 369 LGSPTLQATHSFLPSP-------PLSPLATPPPQAPPALALPPLQAPPSP--PASPP--- 416
Query: 329 LVPAAPPGPGPRPPGAESHGCL---------PATRPPGSDLRESRVQRSRMDSSVSPAAT 379
L P A P P+ P A + L P + P S V S S +P +
Sbjct: 417 LSPLAT--PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 380 TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG-----VEPNPGIPGADHYQTPALEVSH 434
A P PP P + S++ + L +P P P A TP L+
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA--LATPPLQAL- 531
Query: 435 HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLR------PPPPPAWLKG 488
PS +S F G +P SLP P + PPP P +L PP PPA
Sbjct: 532 -----PSPPAS---FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA---S 580
Query: 489 PACRAAREDGEILEELFFGTEGP------PR------PAPPPLPHREGFLGPPASRFSVG 536
P +A R T GP PR P PPP P R P+S S
Sbjct: 581 PTLQAPRRP---------PTPGPDTSVSGPRLTLALAPGPPPPPSRS-----PSSTLSGP 626
Query: 537 TQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPL--PRPPSPAQNP 594
H+ + TS+ G S G + PPP + P R P+P
Sbjct: 627 DLAGHS-----SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 595 QDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPL-SKAP 653
+ P PL P PP++ + G E+ P + P + PGP PG KA
Sbjct: 682 RGAPGAPL-----PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 736
Query: 654 QPVPPGVGELPARGPRLFDFP 674
G + RL + P
Sbjct: 737 AGAGAGASSRSPKQARLGELP 757
Score = 52.0 bits (123), Expect = 5e-06
Identities = 94/364 (25%), Positives = 133/364 (36%), Gaps = 57/364 (15%)
Query: 780 PLAKFPPPSQPQPP----PPPPPSPASLLKSLASVLEGQK-YCYRGTGAAVSTRPGPLPT 834
P A+ P P+PP PPPP +PA+L A+ G+K R G +T P P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 835 TQYSPGPPSGATALPPTSAAP-SAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPM 893
P +G ++ P S P S +G P A + TS GP + RA PGP+
Sbjct: 77 A--GPTRSAGTSSRNPASRPPASGRGERAPPAKN-----TSPGPVSSPGRASGTTRPGPL 129
Query: 894 TPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADP--------------V 939
Q +S + + E R+ + R S P P V
Sbjct: 130 G--QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 940 DTAEPADSGTERLLPPAQAKEEAGGVAAV------SGSCKRRQKEHQKEHRRHRRACKDS 993
PA S R PP + ++ A+ S + +RR R R+ S
Sbjct: 188 GLPRPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 994 ---VGRRPREG-------RAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASK 1043
+ R G RA A PK K + L + R+ + P LG S
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR----PPQVTPPRKDAAPALGPLSS 301
Query: 1044 AKPPTAPAPPSAPAPSAQPT----PPSASVPGKKAREEAPGPPGVSRADMLK-LRSLSEG 1098
+ P P+P +A A PT P S+S+ + A PP S L+ L S
Sbjct: 302 S-PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 1099 PPKE 1102
PP +
Sbjct: 361 PPSQ 364
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 120 bits (301), Expect = 1e-26
Identities = 257/1029 (24%), Positives = 341/1029 (33%), Gaps = 173/1029 (16%)
Query: 7 PPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPG--GRCSASI-GQPPLPA---PL 60
PP + +R G ++ PP PP + +P GR + S G P P PL
Sbjct: 903 PPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPL 962
Query: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLH-GKLESLHGCVQALLREPAQPGLWEQLGQLYES 119
P S +S PS P G+ H G L H A P
Sbjct: 963 PASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPP-----------P 1011
Query: 120 EHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNL 179
+ A + + GGS + PR+ Q L + G P
Sbjct: 1012 QPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS------ 1065
Query: 180 LHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQT- 238
H G GP ++ PP AA+ P+ G+ R+G +QT
Sbjct: 1066 -HHGSAGGGGGSSQGPALRYFQLPP---RAASAAMYVPARS------GRGRKGPLVKQTK 1115
Query: 239 --GLPP-GLPLPPPPLPPPPPPPPPPP----PPLPGLATSPPFQLTKPGLWSTLHGDAWG 291
G P G LPP P P P P PPP P P + P S+ G
Sbjct: 1116 VEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSS------G 1169
Query: 292 PERKGSA----PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESH 347
+GS+ PP + E P+PA P PP P P P A
Sbjct: 1170 RSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSP--------VPPSPSPVPTPASPS 1221
Query: 348 GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN 407
G PAT S + V +R + A + + G + ++
Sbjct: 1222 G--PATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPG 1279
Query: 408 TGLRGVEP-NPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS-LPPGP 465
LR + + G+ A+ Y S G G A S + + G ++ S LPP P
Sbjct: 1280 PRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGS--RAYGGGGGSSAFTSFLPPRP 1337
Query: 466 SSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGF 525
P + L P P RA +E +EG P PPP P +
Sbjct: 1338 LVHPLTG--KALDPASPLGLALAARERALKES----------SEGGGAPQPPPRPPSPRY 1385
Query: 526 LGPPASRFSVGTQDSHTP------PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLAR 579
PP + H P +PP P +G S + P S PP R
Sbjct: 1386 EAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPAS---PPAARR 1442
Query: 580 SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR--PESPRP---RVSF 634
S+ L R P P P + PL L L PP+ H S +R PE P V F
Sbjct: 1443 SL--LHRLP-----PTAPGVGPLLLQLGTEPPAP-HPGVSKPWRSAAPEEPERLPLHVRF 1494
Query: 635 -----PKTP---------EVGPG-PPPGPL-SKAPQPVPPGVGELPARGPRLFDFPPTPL 678
P+ P E GPG PPP P S P P P E G L PP
Sbjct: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASE--ENGLPLLVLPP--- 1549
Query: 679 EDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT 738
PA + DG ++ L + ++ E+ + P PP P +P P
Sbjct: 1550 ------PAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP----DTPAPA 1599
Query: 739 DTAPTTTAPAVAVTTTTTTTTTT----------TATQEEEKKPPPALPPPPPLAKFPPPS 788
P PAVA T +T + T TQ P PP PP P P+
Sbjct: 1600 TPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPA 1659
Query: 789 QPQPPPPPPP----------------------SPASLLKSLASVLEGQKYCYRGTGAAVS 826
PQP P PPP S AS L SL++ G G GA V+
Sbjct: 1660 APQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVA 1719
Query: 827 TRPGPLPT-TQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAG 885
+ P L T Y G G ++ P P PS SGG R
Sbjct: 1720 SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLM---TPSKLRGRALGASGG----LRPGP 1772
Query: 886 EEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPA 945
+ P+TPT P +S+ A ++ + T G A +P P A
Sbjct: 1773 SGGLRDPVTPTS--PTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTA 1830
Query: 946 DSGTERLLP 954
S +LLP
Sbjct: 1831 SSLPRKLLP 1839
Score = 91.3 bits (225), Expect = 7e-18
Identities = 164/667 (24%), Positives = 222/667 (33%), Gaps = 138/667 (20%)
Query: 257 PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSA----PPERQEQRHSLPHP 312
PP P PL G A P L GL A +G PP R+ P P
Sbjct: 1334 PPRPLVHPLTGKALDPASPL---GLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPP 1390
Query: 313 YPYPAPAYTAHPPGHRLVPAAPPGPGPRPPG-----AESHGCLPATRPPGSDLRESRVQR 367
P+ + H P RL A+PP P R G LPA+ P R S + R
Sbjct: 1391 TPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA---RRSLLHR 1447
Query: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
+P + P PG + S++ + + ++ Q
Sbjct: 1448 L---PPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLH----VRFLENCQP 1500
Query: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPP---CPRLLRPPPPPA 484
A S GR PS G P +P S+PP P+SP P L+ PPP P+
Sbjct: 1501 RAPVTS--GRGPPSEDGP-----GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPS 1553
Query: 485 WLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPP 544
EDGE L P PPPL F P +S P
Sbjct: 1554 --------VDVEDGEFLFV---------EPLPPPLEFSNSFEKP----------ESPLTP 1586
Query: 545 TPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTL 604
PP P + +PA P+ PPP +A + L S + D + LT
Sbjct: 1587 GPPHPLPDTP---------APATPLPPVPPPAVAAAPPTLDSTASSLTS-YDSEVATLTQ 1636
Query: 605 ALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664
AP G P P P P P+ GP PPPG S G+ E+
Sbjct: 1637 GASAAP---------GDPHPPGPPAPAAPAPAAPQPGPDPPPGTDS--------GIEEVD 1679
Query: 665 ARGPRLFDFPPTPLEDQFEEPAEFKILPDG-------------LANIMKMLDESIRKEEE 711
+R PLE + +G +A+ ++LD + +
Sbjct: 1680 SRSSS-----DHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDG 1734
Query: 712 QQQHEAGVA--PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK 769
Q + P PP + L+ + P+ + T T+ T +
Sbjct: 1735 QAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT 1794
Query: 770 KPPPAL-----PPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAA 824
AL PP +A P +P+ PP P P+ +SL + L EG
Sbjct: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEG----------- 1843
Query: 825 VSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ----FSTSGG--PW 878
PGP P P G A P SA + + S SS Q S +GG PW
Sbjct: 1844 ----PGP------PPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPW 1893
Query: 879 ARERRAG 885
AR G
Sbjct: 1894 ARGGSGG 1900
Score = 82.8 bits (203), Expect = 3e-15
Identities = 189/785 (24%), Positives = 254/785 (32%), Gaps = 195/785 (24%)
Query: 525 FLGPPASRFS-----VGTQDSHTPPT--PPTP--TTSSSNSNSGSHSSSPAG-------- 567
+L PPA +FS G++D PPT PP P +T S+SG + SP G
Sbjct: 900 YLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSG 959
Query: 568 -------PVSF--PPPP-----YLARSI---DPLP----RPPSPAQNPQDPPLVPLTLAL 606
P SF P PP +S+ PLP PP + PP A
Sbjct: 960 GPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAH 1019
Query: 607 PPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEV------GPGPPPGPLSKAPQPV---P 657
PP PP T GS P+ P PR++ P + GP P PG AP P
Sbjct: 1020 PPHPP---EMETGGS---PDDPPPRLALGPQPSLRGWRGGGPSPTPG----APSPSHHGS 1069
Query: 658 PGVGELPARGP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQH 715
G G ++GP R F PP PA G ++ ++ K E + Q
Sbjct: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPAR-----SGRGRKGPLVKQT--KVEGEPQK 1122
Query: 716 EAGVAPQPPLKEPFASLQSPFPTDTAP----TTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
G+ P P P AS Q P P AP + P + + +T+++ ++ +
Sbjct: 1123 GGGLPPAPSPTSP-ASPQPP-PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAE 1180
Query: 772 PPALP--------------PPPPLAKFPPPSQPQPPPPPPPSPASL--LKSLASVLEGQK 815
PP P P P ++ PP P P P P PA+L + L G
Sbjct: 1181 PPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGA- 1239
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQ-------------GSPQ 862
R G R G G T AAP + P
Sbjct: 1240 -ARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPY 1298
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACE 922
S+ + GG A R G T PP P
Sbjct: 1299 LRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRP--------------------- 1337
Query: 923 TLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKE---- 978
LV + A DPA P+ A A ER L + E GG + E
Sbjct: 1338 -LVHPLTGKALDPASPLGLALAA---RERAL---KESSEGGGAPQPPPRPPSPRYEAPPP 1390
Query: 979 ---HQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
H H H E + P + +RR LG R
Sbjct: 1391 TPHHHSPHAHH-------------EPVLRLWGASPPDPARRELG--------------YR 1423
Query: 1036 PDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGP-PGVSRADMLKLRS 1094
LG K+ P + PA + PT P + E P P PGVS+ RS
Sbjct: 1424 AGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSK----PWRS 1479
Query: 1095 LSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKGK 1154
+ P+ L + + +E+ + S S V S V
Sbjct: 1480 AAPEEPERLPLHVRFLENCQPRAPVTS---------GRGPPSEDGPGVPPPSPRRSV--- 1527
Query: 1155 FRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAF---SPVLLQFCTD---P 1208
P P+ + E LP L PP PS+ +E F P L+F P
Sbjct: 1528 -------PPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
Query: 1209 RNPIT 1213
+P+T
Sbjct: 1581 ESPLT 1585
Score = 80.1 bits (196), Expect = 2e-14
Identities = 174/739 (23%), Positives = 246/739 (33%), Gaps = 149/739 (20%)
Query: 186 RNYGAKRGGPPVKRAAEP-PVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGL 244
R YG G P P+V P+ AL P+ GL+ + R S + G P
Sbjct: 1318 RAYGGGGGSSAFTSFLPPRPLVHPLTGKALD-PASPLGLALAARERALKESSEGGGAP-- 1374
Query: 245 PLPPPPLPPPPPPPPPPPPP---LPGLATSPPFQL-----TKPGLWSTLHGDAWGPERKG 296
PPP PP P PPP P P P +L P + G + K
Sbjct: 1375 --QPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEK- 1431
Query: 297 SAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRP----PGAESHGCLPA 352
S P R SL H P AP G L+ P P P P + P
Sbjct: 1432 SLPASPPAARRSLLHRLPPTAPGV-----GPLLLQLGTEPPAPHPGVSKPWRSAAPEEPE 1486
Query: 353 TRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG 412
P E+ R+ + S P + PS +P + TS +S + GL
Sbjct: 1487 RLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEEN--GLPL 1544
Query: 413 VEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPH-LSLPPGPSSPPPP 471
+ P P D L V ++S KP PH L P P++P PP
Sbjct: 1545 LVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPP 1604
Query: 472 PCPRLLRPPPPPAWLKGPACRAAREDGEI--LEELFFGTEGPPRPAPPPLPH-------R 522
P + PP L A D E+ L + G P P PP P +
Sbjct: 1605 VPPPAVAAAPPT--LDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQ 1662
Query: 523 EGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNS--------------GSHSSSPAGP 568
G PP + + DS + P T SS+++ S G+ + +GP
Sbjct: 1663 PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGP 1722
Query: 569 V-----------------SFPPPPYLARSIDPL--------------PRPPSPAQNPQDP 597
S P PPY + + P P P ++P P
Sbjct: 1723 ELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTP 1782
Query: 598 --PLVPLT---------LALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTP-------- 638
P V +T L PP++ +G E P V P
Sbjct: 1783 TSPTVSVTGAGTDGLLALRACSGPPTA---GVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839
Query: 639 -EVGPGPPPGPLSKAPQPV-PPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILP---- 692
E GPGPPP PL P P+ P L + + L+ A LP
Sbjct: 1840 WEEGPGPPPPPL---PGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARG 1896
Query: 693 ---------DGLANIMKMLDESIRKEEEQQQHEAGVA-----------PQPPLKEPFASL 732
G A+ + S++++ ++ + P+PPL
Sbjct: 1897 GSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPL------- 1949
Query: 733 QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ-----EEEKKPPPALPPPPPLAKFPPP 787
P PT T + TA A T+ + ++++T+T+ E E +PP P P P
Sbjct: 1950 -PPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSP--SLLPA 2006
Query: 788 SQPQPPPPPPPSPASLLKS 806
S+ + P P PS +L S
Sbjct: 2007 SEHKVSPAPRPSSLPILPS 2025
Score = 73.2 bits (178), Expect = 2e-12
Identities = 197/763 (25%), Positives = 245/763 (32%), Gaps = 174/763 (22%)
Query: 3 RAVDPPG----ARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLP- 57
+A+DP A AARE GA P PPPR PP P
Sbjct: 1345 KALDPASPLGLALAARERALKESSEGGGA-----PQPPPR---------------PPSPR 1384
Query: 58 --APLP-PSHGSSSGHPSKPYYAPGAPTPRPLHGKL----------ESLHGCVQALLRE- 103
AP P P H S H GA P P +L +SL A R
Sbjct: 1385 YEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSL 1444
Query: 104 -----PAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNF 158
P PG+ L QL E + + S A P L L N
Sbjct: 1445 LHRLPPTAPGVGPLLLQL------GTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLEN- 1497
Query: 159 HTGSCQHRAKVL----PPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAE----PPVVQPVP 210
CQ RA V PP E + +R+ P RA+E P +V P P
Sbjct: 1498 ----CQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSP---RASEENGLPLLVLPPP 1550
Query: 211 PAALSGPSGE----EGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLP 266
++ GE E L P + ++ L PG P P P P P P PP PPP
Sbjct: 1551 APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPP-- 1608
Query: 267 GLATSPP-FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPP 325
+A +PP T L S A + +AP + PHP PAPA A
Sbjct: 1609 AVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGD--------PHPPGPPAPAAPA--- 1657
Query: 326 GHRLVPAAP-PGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVS--------- 375
PAAP PGP P PPG +S G SD + + SS+S
Sbjct: 1658 -----PAAPQPGPDP-PPGTDS-GIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGG 1710
Query: 376 -----------PAATTACVPYAPSR---------PPGLPGTTTSSSSSSSSNTGLRGVEP 415
P V Y + PP P T S + G+ P
Sbjct: 1711 GGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRP 1770
Query: 416 NP--GIPGADHYQTPALEVSHHGRLG------------------PSAHSSRKPFLGAPAA 455
P G+ +P + V+ G G P A P + P A
Sbjct: 1771 GPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTA 1830
Query: 456 T--PHLSLP--PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTE-- 509
+ P LP GP PPPPP P L P A A I+ EL +
Sbjct: 1831 SSLPRKLLPWEEGPG-PPPPPLPGPLAQP--------QASALATVKASIISELSSKLQQF 1881
Query: 510 GPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPV 569
G A LP G G G DSH P +SS S + +
Sbjct: 1882 GGSSAAGGALPWARGGSG--------GGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLL 1933
Query: 570 SFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCH-----QNTSGSFRR 624
S P P P PP P P A P+ SS Q R
Sbjct: 1934 SKPVSSLFQNWPKP-PLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRP 1992
Query: 625 P---ESPRPRVSFPKTPEVGPGPPPGPLSKAPQ-PVPPGVGEL 663
P +P P + +V P P P L P P+ PG+ ++
Sbjct: 1993 PLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDI 2035
Score = 59.7 bits (143), Expect = 2e-08
Identities = 104/413 (25%), Positives = 125/413 (30%), Gaps = 112/413 (27%)
Query: 325 PGHRLVPA------APPGPG----PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSV 374
P HR P+ PPGPG + GA P PP S D
Sbjct: 864 PHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDD-RPYLAPPAMKFSRSLSVPGSEDIPP 922
Query: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS- 433
P + PY+ P G T S N G G P D P V
Sbjct: 923 PPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGS 982
Query: 434 ------HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLK 487
H G L P+ H PH +PPP P PP PP
Sbjct: 983 REKSLYHSGPLPPAHHH-----------PPH---HHHHHAPPPQPHHHHAHPPHPPEMET 1028
Query: 488 GPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP- 546
G + + PPR A P P G+ G S PTP
Sbjct: 1029 GGS----------------PDDPPPRLALGPQPSLRGWRGGGPS------------PTPG 1060
Query: 547 -PTPTTSSSNSNSGSHSSSPAGPVSFPPP------------------------------P 575
P+P+ S G S PA PP P
Sbjct: 1061 APSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEP 1120
Query: 576 YLARSIDPLPRPPSPAQNPQDPPLV---------PLTLALPPAP-PSSCHQNTSGSFRRP 625
+ P P P SPA +PQ PP V P+ + AP SS +++ GS
Sbjct: 1121 QKGGGLPPAPSPTSPA-SPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEA 1179
Query: 626 ESP-RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPA----RGPRLFDF 673
E P +P P G G P P + A PVPP +P GP DF
Sbjct: 1180 EPPTQPE---PTGGGGGGGSSPSP-APAMSPVPPSPSPVPTPASPSGPATLDF 1228
Score = 45.4 bits (106), Expect = 5e-04
Identities = 116/497 (23%), Positives = 157/497 (31%), Gaps = 86/497 (17%)
Query: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYY----APGAPTPRPLH 87
PP PPP A P S + + + +S P P+ AP AP P
Sbjct: 1603 PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQ 1662
Query: 88 GKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAEL--GP 145
+ G + ++ L + + S + SA GG+ A + GP
Sbjct: 1663 PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGP 1722
Query: 146 RIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPV 205
+ A L G PP + L G R GP PV
Sbjct: 1723 ELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP--SGGLRDPV 1780
Query: 206 VQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPL------PPPPLP------- 252
P +++G +G +GL R C+ T G P+ PP PLP
Sbjct: 1781 TPTSPTVSVTG-AGTDGLLA----LRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPR 1835
Query: 253 ---PPPPPPPPPPPPLPGLATSPP---FQLTKPGLWSTLHGDAW---GPERKGSAPPERQ 303
P P PPPPPLPG P K + S L G G A
Sbjct: 1836 KLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGA----- 1890
Query: 304 EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
+P A G G G HG S L+
Sbjct: 1891 --------------------------LPWARGGSGGG--GDSHHGGASYVPERTSSLQRQ 1922
Query: 364 RV----QRSRMDSSVSPAATTACVPYAPSRPPGL---------PGTTT-SSSSSSSSNTG 409
R+ Q S + VS P P P G PG T+ S+SSSS+S
Sbjct: 1923 RLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRH 1982
Query: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL----SLPPGP 465
L+GVE P +P+L + ++ P+ S P L + P L P G
Sbjct: 1983 LQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGG 2042
Query: 466 SSPPPPPCPRLLRPPPP 482
+ P + PP P
Sbjct: 2043 AGGSADPFAPVFVPPHP 2059
Score = 42.7 bits (99), Expect = 0.003
Identities = 89/429 (20%), Positives = 128/429 (29%), Gaps = 87/429 (20%)
Query: 692 PDGLANIMKMLDESIRKEEEQQQHEAGVAP---QPPLKEPFASLQSPFPTDTAPTTTAPA 748
P GLA++ K + E P +P P L + A P
Sbjct: 841 PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY 900
Query: 749 VAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS-------QPQPPPPPPPSPA 801
+A + + + E+ PP PP PP + P PS P+ P P S
Sbjct: 901 LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG 960
Query: 802 SLLKSLASVLEGQKYCYRGTGAAVST--RPGPLPTTQYSP-------GPP------SGAT 846
L S + +G G+ + GPLP + P PP
Sbjct: 961 PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP 1020
Query: 847 ALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP----- 901
PP + P P + Q S G W R G P PG +P+
Sbjct: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRG--W---RGGGPSPTPGAPSPSHHGSAGGGGG 1075
Query: 902 LSLPPARSESEVLEEISRACETLVERVGRSATDP--ADPVDTAEPADSGTERLLPPAQAK 959
S PA ++ + A + R GR P EP G LPPA +
Sbjct: 1076 SSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGG---LPPAPSP 1132
Query: 960 EEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLG 1019
P + P EK+ +
Sbjct: 1133 TS------------------------------------PASPQPPPAVAAPSEKNSIPIP 1156
Query: 1020 NLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPS---------APAPSAQPTPPSASVP 1070
+ +++ R G +++A+PPT P P +PAP+ P PPS S
Sbjct: 1157 TIIIKAPSTS--SSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV 1214
Query: 1071 GKKAREEAP 1079
A P
Sbjct: 1215 PTPASPSGP 1223
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 120 bits (300), Expect = 1e-26
Identities = 160/644 (24%), Positives = 216/644 (33%), Gaps = 157/644 (24%)
Query: 238 TGLPPGLPLPPPPLPPPPPPPPPPPPPLP------------------------------- 266
T P PLPPPP PPPPPPPPPPPPP P
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQH 679
Query: 267 -GLATSPP------FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPA 319
G PP Q KP + +G P P P P P
Sbjct: 680 SGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ 739
Query: 320 YTAHPPG------HRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRE-SRVQRSRMDS 372
++A PP + APP P P PP +PA PP + + +
Sbjct: 740 FSAPPPPLKIHQVQHITQVAPPTPPPPPP-------IPAPLPPQAPPKPLVTIPAPTSTK 792
Query: 373 SVSPAATTACVP------------------YAPSRPP----GLPGTTTSSSSSSSSNTGL 410
+V+P T A P Y P PP +P T S +
Sbjct: 793 TVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP 852
Query: 411 RGVEPNPGIPGADHYQ------TPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLP-P 463
+ P P + Q PA+E + + P + A S+P P
Sbjct: 853 SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912
Query: 464 GPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHRE 523
P PPPPP L+ PPPPP+ + P PP P P P +
Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAP-------------------PPPPPPTASPTPDKS 953
Query: 524 GFLGPPASRFSVGTQDSHTPPTPPTPTTSSS-NSNSGSHSSSPAGPVSFPPPPYLARSID 582
G G S+ T PPTP +SS S+SG+ P P S+D
Sbjct: 954 GSPGKKTSK----TSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP-----------SVD 998
Query: 583 PLP---RPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSG------------SFRRPE- 626
L PP+ + +P L P P APP N SG S + P
Sbjct: 999 SLVSKFTPPAESGSPSKETLPP-----PAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 627 SPRPR---VSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTP----LE 679
S R + V FP P PPP P ++ P P P P +F +P +
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLP--------PIEIPAVFSGNTSPKVAVVN 1105
Query: 680 DQFEEPAEFKILPDGLANIMKMLDES--IRKEEEQQQHEAGVAPQPPLK-EPFASLQSPF 736
Q ++ ++ + K D + + E +Q A V PQ P + S+Q F
Sbjct: 1106 PQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGF 1165
Query: 737 PTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
D T ++T + ++ + + ALPPPPP
Sbjct: 1166 LADL--NRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPP 1207
Score = 117 bits (294), Expect = 7e-26
Identities = 185/773 (23%), Positives = 264/773 (34%), Gaps = 216/773 (27%)
Query: 270 TSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR-HSLPHPYPYPAPA--------- 319
T P + + S++ +AW ++G+ E + R S+ PY P
Sbjct: 561 TQPAGHVRSQSIVSSVFSEAW---KRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVT 617
Query: 320 -YTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAA 378
YTA P L P PP P P PP P PP + S +P+A
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPPP-------PPPPPP-------------LPSQSAPSA 657
Query: 379 TTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRL 438
+A P + +T + ++S ++G P P
Sbjct: 658 GSAA-------PMFVKYSTITRLQNASQHSGALFKPPTP--------------------- 689
Query: 439 GPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDG 498
P + + + P + +PP PPPPP PPPPP G
Sbjct: 690 ---------PVMQSQSVKPQILVPPNGVVPPPPP------PPPPPT------------PG 722
Query: 499 EILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNS 558
+ +L P P P LP PP V PPTPP P +
Sbjct: 723 SAMAQL------KPAPCAPSLPQFSA-PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP 775
Query: 559 GSHSSSPAGPVSFPPP-------PYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPP 611
+ P V+ P P P + ++ P P PP P Q P P + +PP+PP
Sbjct: 776 ---QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ--PAFPASY-IPPSPP 829
Query: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLF 671
+ P P P + PK PPP PLS PVP V ++ ++ P
Sbjct: 830 T------------PPVPVPPPTLPKQQSFCAKPPPSPLS----PVPSVVKQIASQFPP-- 871
Query: 672 DFPPTP--LEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGV-APQPPLKEP 728
PPTP +E Q +P AN+ +++ + + Q V +P P P
Sbjct: 872 --PPTPPAMESQPLKPVP--------ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP 921
Query: 729 FASLQSPFPTDT---APTTTAPAVAVTTTTTTTT----TTTATQEEEKKPPP-------- 773
+SL P P + AP P A T + + T+ + KKPPP
Sbjct: 922 ESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981
Query: 774 -----ALPPPPP-------LAKFPPPSQPQ-------PPPPPPPSPASLLKS---LASVL 811
A P P ++KF PP++ PPP PP P L S L VL
Sbjct: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 812 EGQKYCYRGTGAAVSTR--------PGPLPTTQYSPGPPSGATALPPTSAAPSAQG---- 859
Q+ C +S R P P + + P PP LPP G
Sbjct: 1042 --QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSP 1099
Query: 860 -----SPQPSASSSSQFSTSGGPWARER---------RAGEEPVPG---PMTPTQPPPPL 902
+PQP S + P +R E+P P PT P L
Sbjct: 1100 KVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSL 1159
Query: 903 SLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPP 955
S+ P L +++R TL + + + AEP + + LPP
Sbjct: 1160 SVQPG-----FLADLNR---TLQRKSITRHGSLSSRMSRAEPTATMDDMALPP 1204
Score = 98.2 bits (243), Expect = 6e-20
Identities = 119/472 (25%), Positives = 162/472 (34%), Gaps = 95/472 (20%)
Query: 540 SHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQN-PQDPP 598
S PP P P + + S P P PPPP P P PP P+Q+ P
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP----PPPPPPPPPLPSQSAPSAGS 659
Query: 599 LVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPP 658
P+ + SG+ +P +P S P++ PP G + P P PP
Sbjct: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV-PPNGVVPPPPPPPPP 718
Query: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
P G + P P + F P L + Q QH
Sbjct: 719 -----PTPGSAMAQLKPAPCAPSLPQ---FSAPPPPL-------------KIHQVQHITQ 757
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPP 778
VAP P P P P P P VT T+T T A + PP PP
Sbjct: 758 VAPPTPPPPP------PIPAPLPPQAP-PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810
Query: 779 PPLAKFP-------PPSQPQPPPP---------------PPPSP----ASLLKSLAS--- 809
PP K P PPS P PP P PPPSP S++K +AS
Sbjct: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870
Query: 810 ------VLEGQKYCYRGTGAAVSTRPG------------PLPTTQYSPGPPSGATALPPT 851
+E Q A + P P+P+ + P PP + PP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 852 SAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSES 911
+P P P ++S SG P ++ + PG P P S + S +
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSP---GKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 912 EVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAG 963
E E + ++LV + T PA+ + S ++ LPP A + G
Sbjct: 988 EHPEPKRPSVDSLVSKF----TPPAE-------SGSPSKETLPPPAAPPKPG 1028
Score = 92.4 bits (228), Expect = 3e-18
Identities = 132/543 (24%), Positives = 194/543 (35%), Gaps = 84/543 (15%)
Query: 704 ESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTA 763
+SI + + G + K S+ P+ + P + P + T TA
Sbjct: 570 QSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIV--------TPYTA 621
Query: 764 TQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEG-QKYCYRGTG 822
+Q P P LPPPPP PPP P PPPPPPP P+ S S KY
Sbjct: 622 SQ-----PSPPLPPPPPP---PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673
Query: 823 AAVSTRPG-----PLPTTQYSPG-------PPSGATALPPTSAAPSAQGS------PQPS 864
S G P P S PP+G PP P GS P P
Sbjct: 674 QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC 733
Query: 865 ASSSSQFSTSGGPW-----------ARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEV 913
A S QFS P A P+P P+ P PP PL PA + ++
Sbjct: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793
Query: 914 LEEI--SRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQ--------AKEEAG 963
+ + A T V + PA P P+ +PP AK
Sbjct: 794 VAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853
Query: 964 GVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGR-AKAKAKVPKEKSRRVLGNLD 1022
++ V K+ + +S +P A K K + ++
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTP---PAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 1023 LQSEEIQGREKSRPDLGGASKAKPPT-APAPPSAPAPSAQPTPPSASVPGKK-AREEAPG 1080
+ S + P+ PP+ PAPP P P+A PTP + PGKK ++ +PG
Sbjct: 911 VPSPDFP---PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPG 967
Query: 1081 ----PPGVSRADMLKLRSLSEGP-PKELKIRLI------KVESG--DKETF--IASEVEE 1125
PP R +K S +E P PK + + ESG KET A+ +
Sbjct: 968 GKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027
Query: 1126 RRLRMADLTISHCAADVVRASRNAKVKGKFRESYLS----PAQSVKPKINTEEKLPREKL 1181
+L ++ + + +++ + G+ ++S + P+ S P E +LP +
Sbjct: 1028 GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPI 1087
Query: 1182 NPP 1184
P
Sbjct: 1088 EIP 1090
Score = 32.0 bits (71), Expect = 5.2
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 3/81 (3%)
Query: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSK---PYYAPGAPTPRPLHG 88
PP PP S P S PP P P SG P K +PG P P
Sbjct: 917 PPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQ 976
Query: 89 KLESLHGCVQALLREPAQPGL 109
+ S+ A EP +P +
Sbjct: 977 RNSSIKSSSGAEHPEPKRPSV 997
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 119 bits (297), Expect = 3e-26
Identities = 250/1021 (24%), Positives = 333/1021 (32%), Gaps = 268/1021 (26%)
Query: 205 VVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL---PPPPPPPPPP 261
++ P PP GP + PGG PP PPPPL PPPPP PP
Sbjct: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPS--------PPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 262 PPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYT 321
PPP+ A SPP L+ P + + P APP P P P PAP
Sbjct: 190 PPPVLE-ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---------PPPVPAPAPPAP 239
Query: 322 A--HPPGHRLVP----------------------AAPPGPGPRPPGA------ESHGCLP 351
A H G RL P A+PP P G+ E H P
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 352 ATR--PPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409
+ PP + +R S + ++ +P APSR P P +S +
Sbjct: 300 RSFKVPPPTPVRTSSIPVQ--EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA 357
Query: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP 469
P P PG PA RLG S + + A TP PP P PP
Sbjct: 358 -----PEPDCPGELKATAPASP-----RLGQSQSQADER-----AGTP----PPAPPLPP 398
Query: 470 PPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPP 529
P P P PPPA P PA PPLP + PP
Sbjct: 399 PAP------PLPPPA-------------------------PPLPPAAPPLPCAQKAAHPP 427
Query: 530 ASRFSVGTQDSHTP-----PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP- 583
A T S +P P PP+P ++S++ S + YL S
Sbjct: 428 AG--FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
Query: 584 --LPRPPSPAQNPQDP-----PLVP-----LTLALPPAPPSSCHQNTSGSFRRPESPRPR 631
L P P PQ P +P L+L PP ++ GS P
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS 545
Query: 632 VSFPKT---PEVGPGPPPGPL---------SKAPQPVPPGVGELPARGPRLF-------- 671
++ P P+ P P + S A + P +G LP + PRL
Sbjct: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK-PRLEGGRICENG 604
Query: 672 ---DFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
D P+ P +LP ML +I + + A P P
Sbjct: 605 ADDDKLSKPVAKNLP-PQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 729 FASL--QSPFPTDTAPTTTAPAV---AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAK 783
A+L +P + PTT A A+ +T TT TTT+ EK PA
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--------- 714
Query: 784 FPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
QP+ P VST P+ G PS
Sbjct: 715 ----GQPEKP---------------------------ASQEVST-----PSQARGEGSPS 738
Query: 844 GATALPPTSAAPSAQGSPQPS----------------ASSSSQFSTSGGPWARERRAGEE 887
AT LP A SA P+ S +S S + + AR AG
Sbjct: 739 EATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG-- 796
Query: 888 PVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADS 947
PG + PP L P S ++ +E+ R PV T E +
Sbjct: 797 --PGEPVEVKEPPGLPAKPPAS-AQPTDELLR-----------------HPV-TGEVVER 835
Query: 948 GTER--LLPPAQAKEEAGGVAAVSGSC----KRRQKEHQKEHRR----HRRACKDS---V 994
G+ LL Q ++ V A G R HQ E H + +S V
Sbjct: 836 GSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV 895
Query: 995 GRRPREGR--AKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPA- 1051
+ P+E + ++P + R+ D + E+ R A A AP+
Sbjct: 896 PKLPKEAEKDSPLTTEIPNKWGPRL--GRDAEGTELSRRHNWTKPEPQAPVAWERVAPSN 953
Query: 1052 -PPSAPAPSAQPTPPSASVPGKKAREE-----APGPPGVSR-----ADMLKLRSLSEGPP 1100
P P P + +PPS S ++ EE P PP S A L+ PP
Sbjct: 954 LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPP 1013
Query: 1101 K 1101
+
Sbjct: 1014 R 1014
Score = 75.5 bits (184), Expect = 4e-13
Identities = 180/807 (22%), Positives = 247/807 (30%), Gaps = 150/807 (18%)
Query: 203 PPVVQPVPPAALSGPS-GEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP- 260
PPV P PPA S + G PGG + + G PP P P
Sbjct: 229 PPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL 288
Query: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAY 320
P P P L F++ P P R S P + ++ AP+
Sbjct: 289 GPNPEPHLTFPRSFKVPPP-----------TPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 321 TAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380
PP + PA+ P R P + G L AT P L +S+ Q + PA
Sbjct: 338 LPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAP-- 394
Query: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGP 440
P P PP P P P +P A A + +H P
Sbjct: 395 ---PLPPPAPPLPP--------------------PAPPLPPAAPPLPCAQKAAH-----P 426
Query: 441 SAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAARED--- 497
A ++ P +PA P P PP P P W R +
Sbjct: 427 PAGFTKTPKSSSPALKP----------KPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476
Query: 498 ---GEILEELFFGTEGPPRPAP--------PPLPHREGFLGPPASRFSVGTQD------- 539
G E+ F P AP P LP +E L PA G +
Sbjct: 477 YLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Query: 540 ---------------SHTPPTPPTPTTSSSNSNSGSHSSSPAGPV------SFPPPPYL- 577
+ P PTP+ + + SS A S PP P L
Sbjct: 537 LTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLE 596
Query: 578 -------ARSIDPLPRPPSPAQNPQDPPLVPLTLALPPA------PPSSCHQNT--SGSF 622
D L +P + PQ L+P T P A PP + + +
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT 656
Query: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQP-VPPGVGELPARGPRLFDFPPTPLEDQ 681
P +P P TP P PL P + LP +L + Q
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 682 FEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP-FASLQSPFPTDT 740
E+PA ++ A E+ R + + A PP P + +
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAF---PPKTSPGGGEVPCLYKPHC 773
Query: 741 APTTTAPAVAVTTTTTTTTTTTATQEE-EKKPPPALPPPPPLAKFPPPSQPQPPPP---- 795
++ + VAV T E E K PP LP PP + P + P
Sbjct: 774 HQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVV 833
Query: 796 PPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL-----------PTTQYSPGPPSG 844
SP +LL LA+ QK G S+ PG L + +S G P+
Sbjct: 834 ERGSPMALL--LAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNS 891
Query: 845 ATALPP-----------TSAAPSAQGSPQPSASSSSQFSTSGG---PWARERRAGEEPVP 890
T +P T+ P+ G + ++ S P + A E P
Sbjct: 892 FTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAP 951
Query: 891 GPMTPTQP-PPPLSLPPARSESEVLEE 916
+ P P S PP+ S EE
Sbjct: 952 SNLPQGHPLPKSFSSPPSPSNKREEEE 978
Score = 58.9 bits (141), Expect = 4e-08
Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 42/360 (11%)
Query: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK 815
T + + TAT + + P L P A+ P P + +S++ G
Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875
Y G RPG P PP G PP + GSP PS S++
Sbjct: 120 RLYSSVG---DLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA------ 170
Query: 876 GPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD- 934
P P P+ PPPP PP VLE +S TL + D
Sbjct: 171 ------------PPPPPLLLEPPPPPSMAPP---PPPVLEALSPP-HTLSSPSIPTPPDF 214
Query: 935 --PADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKD 992
PA P+ P PPA A G + K + R A +
Sbjct: 215 IPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 993 SVGRRPREGRAKAKAKVPK-----EKSRRVLGNLDLQSEEI---QGREKSRPDLGGASKA 1044
S R P E + A P+ +S +V +++ I + +E R + GA+K
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE-EGATKK 333
Query: 1045 KPPTAPAPPS---APAPSAQP-TPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPP 1100
P P PPS PA P P PG + + AP P + ++ PP
Sbjct: 334 APSRLPLPPSFHIRPASQVYPDRAPEPDCPG-ELKATAPASPRLGQSQSQADERAGTPPP 392
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 119 bits (297), Expect = 3e-26
Identities = 250/1021 (24%), Positives = 333/1021 (32%), Gaps = 268/1021 (26%)
Query: 205 VVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL---PPPPPPPPPP 261
++ P PP GP + PGG PP PPPPL PPPPP PP
Sbjct: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPS--------PPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 262 PPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYT 321
PPP+ A SPP L+ P + + P APP P P P PAP
Sbjct: 190 PPPVLE-ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---------PPPVPAPAPPAP 239
Query: 322 A--HPPGHRLVP----------------------AAPPGPGPRPPGA------ESHGCLP 351
A H G RL P A+PP P G+ E H P
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 352 ATR--PPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409
+ PP + +R S + ++ +P APSR P P +S +
Sbjct: 300 RSFKVPPPTPVRTSSIPVQ--EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA 357
Query: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP 469
P P PG PA RLG S + + A TP PP P PP
Sbjct: 358 -----PEPDCPGELKATAPASP-----RLGQSQSQADER-----AGTP----PPAPPLPP 398
Query: 470 PPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPP 529
P P P PPPA P PA PPLP + PP
Sbjct: 399 PAP------PLPPPA-------------------------PPLPPAAPPLPCAQKAAHPP 427
Query: 530 ASRFSVGTQDSHTP-----PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP- 583
A T S +P P PP+P ++S++ S + YL S
Sbjct: 428 AG--FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
Query: 584 --LPRPPSPAQNPQDP-----PLVP-----LTLALPPAPPSSCHQNTSGSFRRPESPRPR 631
L P P PQ P +P L+L PP ++ GS P
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS 545
Query: 632 VSFPKT---PEVGPGPPPGPL---------SKAPQPVPPGVGELPARGPRLF-------- 671
++ P P+ P P + S A + P +G LP + PRL
Sbjct: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK-PRLEGGRICENG 604
Query: 672 ---DFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
D P+ P +LP ML +I + + A P P
Sbjct: 605 ADDDKLSKPVAKNLP-PQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 729 FASL--QSPFPTDTAPTTTAPAV---AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAK 783
A+L +P + PTT A A+ +T TT TTT+ EK PA
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--------- 714
Query: 784 FPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
QP+ P VST P+ G PS
Sbjct: 715 ----GQPEKP---------------------------ASQEVST-----PSQARGEGSPS 738
Query: 844 GATALPPTSAAPSAQGSPQPS----------------ASSSSQFSTSGGPWARERRAGEE 887
AT LP A SA P+ S +S S + + AR AG
Sbjct: 739 EATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG-- 796
Query: 888 PVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADS 947
PG + PP L P S ++ +E+ R PV T E +
Sbjct: 797 --PGEPVEVKEPPGLPAKPPAS-AQPTDELLR-----------------HPV-TGEVVER 835
Query: 948 GTER--LLPPAQAKEEAGGVAAVSGSC----KRRQKEHQKEHRR----HRRACKDS---V 994
G+ LL Q ++ V A G R HQ E H + +S V
Sbjct: 836 GSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV 895
Query: 995 GRRPREGR--AKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPA- 1051
+ P+E + ++P + R+ D + E+ R A A AP+
Sbjct: 896 PKLPKEAEKDSPLTTEIPNKWGPRL--GRDAEGTELSRRHNWTKPEPQAPVAWERVAPSN 953
Query: 1052 -PPSAPAPSAQPTPPSASVPGKKAREE-----APGPPGVSR-----ADMLKLRSLSEGPP 1100
P P P + +PPS S ++ EE P PP S A L+ PP
Sbjct: 954 LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPP 1013
Query: 1101 K 1101
+
Sbjct: 1014 R 1014
Score = 75.5 bits (184), Expect = 4e-13
Identities = 180/807 (22%), Positives = 247/807 (30%), Gaps = 150/807 (18%)
Query: 203 PPVVQPVPPAALSGPS-GEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP- 260
PPV P PPA S + G PGG + + G PP P P
Sbjct: 229 PPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL 288
Query: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAY 320
P P P L F++ P P R S P + ++ AP+
Sbjct: 289 GPNPEPHLTFPRSFKVPPP-----------TPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 321 TAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380
PP + PA+ P R P + G L AT P L +S+ Q + PA
Sbjct: 338 LPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAP-- 394
Query: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGP 440
P P PP P P P +P A A + +H P
Sbjct: 395 ---PLPPPAPPLPP--------------------PAPPLPPAAPPLPCAQKAAH-----P 426
Query: 441 SAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAARED--- 497
A ++ P +PA P P PP P P W R +
Sbjct: 427 PAGFTKTPKSSSPALKP----------KPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476
Query: 498 ---GEILEELFFGTEGPPRPAP--------PPLPHREGFLGPPASRFSVGTQD------- 539
G E+ F P AP P LP +E L PA G +
Sbjct: 477 YLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Query: 540 ---------------SHTPPTPPTPTTSSSNSNSGSHSSSPAGPV------SFPPPPYL- 577
+ P PTP+ + + SS A S PP P L
Sbjct: 537 LTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLE 596
Query: 578 -------ARSIDPLPRPPSPAQNPQDPPLVPLTLALPPA------PPSSCHQNT--SGSF 622
D L +P + PQ L+P T P A PP + + +
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT 656
Query: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQP-VPPGVGELPARGPRLFDFPPTPLEDQ 681
P +P P TP P PL P + LP +L + Q
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 682 FEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP-FASLQSPFPTDT 740
E+PA ++ A E+ R + + A PP P + +
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAF---PPKTSPGGGEVPCLYKPHC 773
Query: 741 APTTTAPAVAVTTTTTTTTTTTATQEE-EKKPPPALPPPPPLAKFPPPSQPQPPPP---- 795
++ + VAV T E E K PP LP PP + P + P
Sbjct: 774 HQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVV 833
Query: 796 PPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL-----------PTTQYSPGPPSG 844
SP +LL LA+ QK G S+ PG L + +S G P+
Sbjct: 834 ERGSPMALL--LAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNS 891
Query: 845 ATALPP-----------TSAAPSAQGSPQPSASSSSQFSTSGG---PWARERRAGEEPVP 890
T +P T+ P+ G + ++ S P + A E P
Sbjct: 892 FTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAP 951
Query: 891 GPMTPTQP-PPPLSLPPARSESEVLEE 916
+ P P S PP+ S EE
Sbjct: 952 SNLPQGHPLPKSFSSPPSPSNKREEEE 978
Score = 58.9 bits (141), Expect = 4e-08
Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 42/360 (11%)
Query: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK 815
T + + TAT + + P L P A+ P P + +S++ G
Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875
Y G RPG P PP G PP + GSP PS S++
Sbjct: 120 RLYSSVG---DLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA------ 170
Query: 876 GPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD- 934
P P P+ PPPP PP VLE +S TL + D
Sbjct: 171 ------------PPPPPLLLEPPPPPSMAPP---PPPVLEALSPP-HTLSSPSIPTPPDF 214
Query: 935 --PADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKD 992
PA P+ P PPA A G + K + R A +
Sbjct: 215 IPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 993 SVGRRPREGRAKAKAKVPK-----EKSRRVLGNLDLQSEEI---QGREKSRPDLGGASKA 1044
S R P E + A P+ +S +V +++ I + +E R + GA+K
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE-EGATKK 333
Query: 1045 KPPTAPAPPS---APAPSAQP-TPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPP 1100
P P PPS PA P P PG + + AP P + ++ PP
Sbjct: 334 APSRLPLPPSFHIRPASQVYPDRAPEPDCPG-ELKATAPASPRLGQSQSQADERAGTPPP 392
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 119 bits (297), Expect = 3e-26
Identities = 250/1021 (24%), Positives = 333/1021 (32%), Gaps = 268/1021 (26%)
Query: 205 VVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL---PPPPPPPPPP 261
++ P PP GP + PGG PP PPPPL PPPPP PP
Sbjct: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPS--------PPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 262 PPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYT 321
PPP+ A SPP L+ P + + P APP P P P PAP
Sbjct: 190 PPPVLE-ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP---------PPPVPAPAPPAP 239
Query: 322 A--HPPGHRLVP----------------------AAPPGPGPRPPGA------ESHGCLP 351
A H G RL P A+PP P G+ E H P
Sbjct: 240 ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFP 299
Query: 352 ATR--PPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409
+ PP + +R S + ++ +P APSR P P +S +
Sbjct: 300 RSFKVPPPTPVRTSSIPVQ--EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA 357
Query: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP 469
P P PG PA RLG S + + A TP PP P PP
Sbjct: 358 -----PEPDCPGELKATAPASP-----RLGQSQSQADER-----AGTP----PPAPPLPP 398
Query: 470 PPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPP 529
P P P PPPA P PA PPLP + PP
Sbjct: 399 PAP------PLPPPA-------------------------PPLPPAAPPLPCAQKAAHPP 427
Query: 530 ASRFSVGTQDSHTP-----PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP- 583
A T S +P P PP+P ++S++ S + YL S
Sbjct: 428 AG--FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
Query: 584 --LPRPPSPAQNPQDP-----PLVP-----LTLALPPAPPSSCHQNTSGSFRRPESPRPR 631
L P P PQ P +P L+L PP ++ GS P
Sbjct: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS 545
Query: 632 VSFPKT---PEVGPGPPPGPL---------SKAPQPVPPGVGELPARGPRLF-------- 671
++ P P+ P P + S A + P +G LP + PRL
Sbjct: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPK-PRLEGGRICENG 604
Query: 672 ---DFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
D P+ P +LP ML +I + + A P P
Sbjct: 605 ADDDKLSKPVAKNLP-PQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 729 FASL--QSPFPTDTAPTTTAPAV---AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAK 783
A+L +P + PTT A A+ +T TT TTT+ EK PA
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPA--------- 714
Query: 784 FPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
QP+ P VST P+ G PS
Sbjct: 715 ----GQPEKP---------------------------ASQEVST-----PSQARGEGSPS 738
Query: 844 GATALPPTSAAPSAQGSPQPS----------------ASSSSQFSTSGGPWARERRAGEE 887
AT LP A SA P+ S +S S + + AR AG
Sbjct: 739 EATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG-- 796
Query: 888 PVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADS 947
PG + PP L P S ++ +E+ R PV T E +
Sbjct: 797 --PGEPVEVKEPPGLPAKPPAS-AQPTDELLR-----------------HPV-TGEVVER 835
Query: 948 GTER--LLPPAQAKEEAGGVAAVSGSC----KRRQKEHQKEHRR----HRRACKDS---V 994
G+ LL Q ++ V A G R HQ E H + +S V
Sbjct: 836 GSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV 895
Query: 995 GRRPREGR--AKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPA- 1051
+ P+E + ++P + R+ D + E+ R A A AP+
Sbjct: 896 PKLPKEAEKDSPLTTEIPNKWGPRL--GRDAEGTELSRRHNWTKPEPQAPVAWERVAPSN 953
Query: 1052 -PPSAPAPSAQPTPPSASVPGKKAREE-----APGPPGVSR-----ADMLKLRSLSEGPP 1100
P P P + +PPS S ++ EE P PP S A L+ PP
Sbjct: 954 LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPP 1013
Query: 1101 K 1101
+
Sbjct: 1014 R 1014
Score = 75.5 bits (184), Expect = 4e-13
Identities = 180/807 (22%), Positives = 247/807 (30%), Gaps = 150/807 (18%)
Query: 203 PPVVQPVPPAALSGPS-GEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP- 260
PPV P PPA S + G PGG + + G PP P P
Sbjct: 229 PPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL 288
Query: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAY 320
P P P L F++ P P R S P + ++ AP+
Sbjct: 289 GPNPEPHLTFPRSFKVPPP-----------TPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 321 TAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380
PP + PA+ P R P + G L AT P L +S+ Q + PA
Sbjct: 338 LPLPPSFHIRPASQVYP-DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAP-- 394
Query: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGP 440
P P PP P P P +P A A + +H P
Sbjct: 395 ---PLPPPAPPLPP--------------------PAPPLPPAAPPLPCAQKAAH-----P 426
Query: 441 SAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAARED--- 497
A ++ P +PA P P PP P P W R +
Sbjct: 427 PAGFTKTPKSSSPALKP----------KPNPPSPENTASSAPVDWRDPSQMEKLRNELAA 476
Query: 498 ---GEILEELFFGTEGPPRPAP--------PPLPHREGFLGPPASRFSVGTQD------- 539
G E+ F P AP P LP +E L PA G +
Sbjct: 477 YLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Query: 540 ---------------SHTPPTPPTPTTSSSNSNSGSHSSSPAGPV------SFPPPPYL- 577
+ P PTP+ + + SS A S PP P L
Sbjct: 537 LTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLE 596
Query: 578 -------ARSIDPLPRPPSPAQNPQDPPLVPLTLALPPA------PPSSCHQNT--SGSF 622
D L +P + PQ L+P T P A PP + + +
Sbjct: 597 GGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT 656
Query: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQP-VPPGVGELPARGPRLFDFPPTPLEDQ 681
P +P P TP P PL P + LP +L + Q
Sbjct: 657 LWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQ 716
Query: 682 FEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP-FASLQSPFPTDT 740
E+PA ++ A E+ R + + A PP P + +
Sbjct: 717 PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAF---PPKTSPGGGEVPCLYKPHC 773
Query: 741 APTTTAPAVAVTTTTTTTTTTTATQEE-EKKPPPALPPPPPLAKFPPPSQPQPPPP---- 795
++ + VAV T E E K PP LP PP + P + P
Sbjct: 774 HQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVV 833
Query: 796 PPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL-----------PTTQYSPGPPSG 844
SP +LL LA+ QK G S+ PG L + +S G P+
Sbjct: 834 ERGSPMALL--LAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNS 891
Query: 845 ATALPP-----------TSAAPSAQGSPQPSASSSSQFSTSGG---PWARERRAGEEPVP 890
T +P T+ P+ G + ++ S P + A E P
Sbjct: 892 FTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAP 951
Query: 891 GPMTPTQP-PPPLSLPPARSESEVLEE 916
+ P P S PP+ S EE
Sbjct: 952 SNLPQGHPLPKSFSSPPSPSNKREEEE 978
Score = 58.9 bits (141), Expect = 4e-08
Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 42/360 (11%)
Query: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK 815
T + + TAT + + P L P A+ P P + +S++ G
Sbjct: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875
Y G RPG P PP G PP + GSP PS S++
Sbjct: 120 RLYSSVG---DLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA------ 170
Query: 876 GPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD- 934
P P P+ PPPP PP VLE +S TL + D
Sbjct: 171 ------------PPPPPLLLEPPPPPSMAPP---PPPVLEALSPP-HTLSSPSIPTPPDF 214
Query: 935 --PADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKD 992
PA P+ P PPA A G + K + R A +
Sbjct: 215 IPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
Query: 993 SVGRRPREGRAKAKAKVPK-----EKSRRVLGNLDLQSEEI---QGREKSRPDLGGASKA 1044
S R P E + A P+ +S +V +++ I + +E R + GA+K
Sbjct: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE-EGATKK 333
Query: 1045 KPPTAPAPPS---APAPSAQP-TPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPP 1100
P P PPS PA P P PG + + AP P + ++ PP
Sbjct: 334 APSRLPLPPSFHIRPASQVYPDRAPEPDCPG-ELKATAPASPRLGQSQSQADERAGTPPP 392
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 113 bits (282), Expect = 2e-24
Identities = 165/722 (22%), Positives = 226/722 (31%), Gaps = 148/722 (20%)
Query: 241 PPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP 300
P P PPP PP P PP T PP P + +T P +PP
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT----TTPPPTTTPSPP 1457
Query: 301 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
P P T PP +PP P PP + P T P
Sbjct: 1458 ISTTTT---------PPPTTTPSPP---TTTPSPPTTTPSPPTTTTTTPPPTTTP----- 1500
Query: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
SP TT P P+ LP TTT S ++++ T P P
Sbjct: 1501 --------------SPPTTTPITP--PASTTTLPPTTTPSPPTTTTTT------PPPTTT 1538
Query: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480
+ TP + P ++ P P+ P + P P++ P PP PP
Sbjct: 1539 PSPPTTTP---------ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589
Query: 481 ------PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS 534
PPP P T P P P P + PP S +
Sbjct: 1590 TITTTTPPPTTTPSPPTT---------------TTTTPPPTTTPSPPTTTPITPPTSTTT 1634
Query: 535 VGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLP--RPPSPAQ 592
+ + TP PPT TT+ +++P+ P + P P + + P P P SP
Sbjct: 1635 L--PPTTTPSPPPTTTTTP------PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPIT 1686
Query: 593 NPQDPPLVPLTLALPPAPPSS-CHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSK 651
PP +T P PSS T+ S SP P +P P PP ++
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746
Query: 652 AP----------QPVPPGVGELPARGPRLFDFPPTPL-------------EDQFEEPAEF 688
P P+PP + P P P TP + F +P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITP-PTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGD 1805
Query: 689 KIL------PDGLANI-----------MKMLDESIRKE-------EEQQQHEAGVAPQP- 723
L P ANI + L +++ + + + Q GV P
Sbjct: 1806 TELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAF 1865
Query: 724 ----PLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP 779
+ + T T TT P TT TTTTT T T P P
Sbjct: 1866 CLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1925
Query: 780 PLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP 839
P P P +P + ++ TG T TT +P
Sbjct: 1926 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-------PTPTGTQTPTTTPITTTTTVTP 1978
Query: 840 GP-PSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQ 897
P P+G T + +P P+ + + +T+ P P P G TPT
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTT 2036
Query: 898 PP 899
P
Sbjct: 2037 TP 2038
Score = 100 bits (248), Expect = 2e-20
Identities = 89/401 (22%), Positives = 132/401 (32%), Gaps = 33/401 (8%)
Query: 508 TEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAG 567
T PP P P P L PP + S T + TPP TP+ + + + +++P+
Sbjct: 1398 TPSPPTTTPSPPPTSTTTL-PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 568 PVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPES 627
P+S P P PSP PP P+PP++ +
Sbjct: 1457 PISTTTTP-------PPTTTPSPPTTTPSPPTTT------PSPPTTT-----------TT 1492
Query: 628 PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAE 687
P + P P P PP + P P P P P P
Sbjct: 1493 TPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1552
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAP 747
LP + P PP + P+ TTT P
Sbjct: 1553 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612
Query: 748 AVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSL 807
T + TTT T PP P PPP PP P PP +P+ + +
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672
Query: 808 ASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQP---S 864
+ + ++T P P TT +P P + ++ T+ PS+ +P P +
Sbjct: 1673 TTPPPTTT-----PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTT 1727
Query: 865 ASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
++ S +T P P+T T PP ++ P
Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768
Score = 99.8 bits (247), Expect = 2e-20
Identities = 106/431 (24%), Positives = 137/431 (31%), Gaps = 77/431 (17%)
Query: 542 TPPTPPT-----PTTSSSNSNSGSHSSSPAGPVSFPPP-----PYLARSIDPLP--RPPS 589
T P+PPT P TS++ + S P + PPP P + + P P P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 590 PAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPL 649
P PP P T PP S T + P + P P P PP
Sbjct: 1457 PISTTTTPP--PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 650 SKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKE 709
+ P P P P P P LP
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP----------------- 1557
Query: 710 EEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK 769
P PP P T T P TT P+ TTT + T TT T
Sbjct: 1558 -------PTTTPSPP----------PTTTTTPPPTTTPSPPTTTTPSPPTITTTT----- 1595
Query: 770 KPPPALPPPPPLAKF---PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
PPP P PP PP + P PP P +P + +L T +
Sbjct: 1596 -PPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654
Query: 827 TRPGPLPTTQYSPGPPSGATALPPTSAAPSA------------QGSPQPSASSSSQFSTS 874
T P P TT +P PP T PP + PS+ +P P+ + SS +T+
Sbjct: 1655 TTPSPPTTT--TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 875 GGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD 934
P + P P P T T P P + P + L + + + S T
Sbjct: 1713 TTP-----SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767
Query: 935 PA-DPVDTAEP 944
P P T P
Sbjct: 1768 PTFSPFSTTTP 1778
Score = 83.2 bits (204), Expect = 2e-15
Identities = 90/358 (25%), Positives = 118/358 (32%), Gaps = 62/358 (17%)
Query: 632 VSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKIL 691
++ P P P PPP + P P P PPT P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP-----PPTTTP---SPPITTTTT 1447
Query: 692 PDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPL---KEPFASLQSPFPTDT-APTTTAP 747
P + + P PP P + +P PT T +P TT P
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 748 AVAVTTTTT----------TTTTTTATQEEEKKPPPALP--PPPPLAKFPPPSQPQPPP- 794
+TTT TTTTTT PP P PP PP + P PPP
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567
Query: 795 ---PPPPS-----PASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP------G 840
PPP+ P + S ++ +T P PTT SP
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627
Query: 841 PPSGATALPPT---SAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQ 897
PP+ T LPPT S P+ +P P+ + S +T+ P P+T T
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP--------------PITTTT 1673
Query: 898 PPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPP 955
PPP + P S + S T+ T P+ P+ T S T PP
Sbjct: 1674 TPPPTTTP----SSPITTTPSPPTTTMT--TPSPTTTPSSPITTTTTPSSTTTPSPPP 1725
Score = 81.6 bits (200), Expect = 6e-15
Identities = 154/729 (21%), Positives = 212/729 (29%), Gaps = 100/729 (13%)
Query: 195 PPVKRAAEPPVVQPVPPAALS---------GPSGEEGLSPGGKRRRGCNSEQTGLPPGLP 245
PP PP P PP + P +P T PP
Sbjct: 1409 PPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTT 1468
Query: 246 LPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305
P PP P PP P PP T PP P + + A + P
Sbjct: 1469 TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT 1528
Query: 306 RHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRV 365
+ P P P+P T PP P PP + P T P
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS--------- 1579
Query: 366 QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHY 425
P TT P + P P TTT S ++++ T P+P
Sbjct: 1580 ---------PPTTTTPSPPTITTTTP--PPTTTPSPPTTTTTTPPPTTTPSPPTT----- 1623
Query: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP----- 480
TP + P ++ P P+ P + P P++ P PP PP
Sbjct: 1624 -TP---------ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 481 -PPPAWLKGPACRAAREDGEILEELFFGTEGPPRP-APPPLPHREGFLGPPASRFSVGTQ 538
PPP T P P P PP + + +
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733
Query: 539 DSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDP- 597
+ TP P T T+ + +SSP PP SI P P P P
Sbjct: 1734 TT-TPSPPTTTMTTLPPTT----TSSPLTTTPLPP------SITPPTFSPFSTTTPTTPC 1782
Query: 598 -PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPV 656
PL T L P +F +P + GPG +A
Sbjct: 1783 VPLCNWTGWLDSGKP---------NFHKPGGDTELIG----DVCGPGWAANISCRATMYP 1829
Query: 657 PPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHE 716
+G+L G + L + E+ P G+ + L+ I + + +
Sbjct: 1830 DVPIGQL---GQTVVCDVSVGLICKNEDQK-----PGGVIPMAFCLNYEINVQCCECVTQ 1881
Query: 717 AGVAPQPPLKEPFASLQSPFPTDT----APTTTAPAVAVTTTTTTTTTTTATQEEEKKPP 772
+ P +P T T PT T TT TTTTT T T
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941
Query: 773 PALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
P P P P P +P + ++ TG T
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-------PTPTGTQTPTTTPIT 1994
Query: 833 PTTQYSPGP-PSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP- 890
TT +P P P+G T + +P P+ + + +T+ P P P
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 2052
Query: 891 GPMTPTQPP 899
G TPT P
Sbjct: 2053 GTQTPTTTP 2061
Score = 80.5 bits (197), Expect = 1e-14
Identities = 107/447 (23%), Positives = 152/447 (34%), Gaps = 85/447 (19%)
Query: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSH 434
SP TT P P+ LP TTT S ++++ T P+P I TP +
Sbjct: 1400 SPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT---TPPPTTTP 1454
Query: 435 HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAA 494
P + ++ P P+ P + P P++ P PP PPP
Sbjct: 1455 SP---PISTTTTPPPTTTPS--PPTTTPSPPTTTPSPPTTTTTTPPPTT----------- 1498
Query: 495 REDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSS 554
T PP P P L PP + S T + TPP TP+ ++
Sbjct: 1499 -------------TPSPPTTTPITPPASTTTL-PPTTTPSPPTTTTTTPPPTTTPSPPTT 1544
Query: 555 NSNSGSHSSSPAGPVSFP-PPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP---PAP 610
+ S++ P + P PPP + P P P PP + T P P+P
Sbjct: 1545 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604
Query: 611 PSSCHQNTSGSFRRPESPRPRVSFPKTPEVG---------PGPPPGPLSKAPQPVPPGVG 661
P++ T+ + +P P + P TP P PPP + P P
Sbjct: 1605 PTT----TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660
Query: 662 ELPARGPRLFDF---PPT-----PLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQ 713
P + PPT P+ P P + +
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST-- 1718
Query: 714 QHEAGVAPQPPLKEPFASLQSPFPTDT--APTTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
P PP ++ +P PT T PTTT + TTT++ TTT
Sbjct: 1719 -----TTPSPPP----TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL-------- 1761
Query: 772 PPALPPPPPLAKFPPPSQPQPPPPPPP 798
PP++ PP F P S P P P
Sbjct: 1762 PPSITPP----TFSPFSTTTPTTPCVP 1784
Score = 76.3 bits (186), Expect = 2e-13
Identities = 125/603 (20%), Positives = 187/603 (31%), Gaps = 45/603 (7%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 3806
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 3807 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3859
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3860 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3919
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 3920 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3974
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3975 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 4026
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 4083
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 4084 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4143
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P PP
Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203
Query: 785 PPPSQ-PQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
P ++ PPP S +S +S L A+ P+T +P S
Sbjct: 4204 APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTS 4263
Query: 844 GA-TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPL 902
G T PP S S G+P ++ +T+G A + TPT P PL
Sbjct: 4264 GGHTLSPPPSTTTSPPGTP-------TRGTTTGSSSAPTPSTVQTTTTSAWTPT--PTPL 4314
Query: 903 SLP 905
S P
Sbjct: 4315 STP 4317
Score = 67.8 bits (164), Expect = 9e-11
Identities = 125/620 (20%), Positives = 189/620 (30%), Gaps = 64/620 (10%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 1966
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 1967 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2019
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2079
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2080 PTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTT 2134
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P+ Q P P+ T P
Sbjct: 2135 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPT 2186
Query: 609 APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSK----APQPVPPGVGELP 664
P+ T+ P + V+ TP P P++ P P P G + P
Sbjct: 2187 PTPTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTP 2241
Query: 665 ARGP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQ 722
P PTP + P I + V P
Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2301
Query: 723 P-----------PLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
P P+ +P PT T TT P + TTT T T T T TQ P
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTP 2360
Query: 772 ----PPALPPPPPLAKFPPPSQP------QPPPPPPPSPASLLKSLASVLEGQKYCYRGT 821
P P P P + P P P P + + + T
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2420
Query: 822 GAAVSTRPGPLPTTQYSPGP-PSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWAR 880
G T TT +P P P+G T + +P P+ + + +T+ P
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITT 2478
Query: 881 ERRAGEEPVP-GPMTPTQPP 899
P P G TPT P
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTP 2498
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2012
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2013 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2065
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2125
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2126 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2180
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2181 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2232
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2289
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 2466
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 2467 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 2521
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2150
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2151 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2203
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2263
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2264 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2318
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2319 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2370
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2427
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 2604
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 2605 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 2659
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2288
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2289 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2341
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2402 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2456
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2457 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2508
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2565
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 2742
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 2743 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 2797
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2426
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2427 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2479
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2539
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2540 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2594
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2595 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2646
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2703
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 2880
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 2881 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 2935
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2564
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2565 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2617
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2677
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2678 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2732
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2733 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2784
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2841
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3018
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3019 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3073
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2702
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2703 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2755
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2816 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 2870
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 2871 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 2922
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 2979
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3156
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3157 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3211
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2840
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2841 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 2893
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2953
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 2954 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3008
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3009 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 3060
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 3117
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3294
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3295 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3349
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 2978
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 2979 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3031
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3091
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 3092 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3146
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3147 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 3198
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 3255
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3432
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3433 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3487
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 3116
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 3117 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3169
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 3230 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3284
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3285 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 3336
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 3393
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3570
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3571 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3625
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 3254
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 3255 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3307
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3308 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 3368 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3422
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3423 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 3474
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 3531
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3708
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3709 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3763
Score = 65.1 bits (157), Expect = 6e-10
Identities = 117/597 (19%), Positives = 180/597 (30%), Gaps = 41/597 (6%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 3392
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 3393 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3445
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 3506 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 3560
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 3561 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 3612
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 3669
Query: 667 GP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP 724
P PTP + P I + V P P
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 725 LKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKF 784
+P T T T T T TTT TTT T P P
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789
Query: 785 PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-PS 843
P P P +P + + + + TG T TT +P P P+
Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPT 3846
Query: 844 GATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 3847 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 3901
Score = 62.0 bits (149), Expect = 5e-09
Identities = 129/629 (20%), Positives = 200/629 (31%), Gaps = 76/629 (12%)
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P P T P + P P P G ++ P T + + + +
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPT 3898
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+P TT V P+ P G TT+ +++++ V P P G T + +
Sbjct: 3899 TTPITTTTTVTPTPT-PTGTQTPTTTPITTTTT------VTPTPTPTGTQTPTTTPITTT 3951
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL-----LRPPPPPAWLKG 488
P+ ++ P T ++ P P+ P + + P P P +
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011
Query: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
P + G P P+ P GTQ T P T
Sbjct: 4012 PTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPITTT 4066
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
T + + + +G+ + + P ++ P P P Q P P+ T P
Sbjct: 4067 TTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVTPT 4118
Query: 609 APPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTPTT 4175
Query: 667 GP----RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQ------QHE 716
P PTP Q P P ES + + +
Sbjct: 4176 TPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTEST 4235
Query: 717 AGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP 776
++ PP E ++ +P T TAPTTT+ ++ +TTT+ T +
Sbjct: 4236 TLLSTLPPAIEMTST--APPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293
Query: 777 PPPPLAKFPPPSQPQPPPPP------------PPSPASLLKSLASVLEGQKYCYRGTGAA 824
P P + S P P P P P+S+L + VL Y G
Sbjct: 4294 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--ICCVLND---TYYAPGEE 4348
Query: 825 VSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQG-SPQPSASSSSQFSTSGGPWARERR 883
V G T Y T + PS +P PS S+ + S P
Sbjct: 4349 VYN--GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTP------ 4400
Query: 884 AGEEPVPGPMTPTQPPPPLSLPPARSESE 912
+P PG T+PP P R E+E
Sbjct: 4401 --SKPTPG----TKPPECPDFDPPRQENE 4423
Score = 57.8 bits (138), Expect = 9e-08
Identities = 147/719 (20%), Positives = 209/719 (29%), Gaps = 88/719 (12%)
Query: 210 PPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPP---GLPLPPPPLPPPPPPPP------- 259
PP ++ PS SP + T LPP PL PLPP PP
Sbjct: 1724 PPTTMTTPSPTTTPSPP-------TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776
Query: 260 -PPPPPLP-----GLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY 313
P P +P G S KPG + L GD GP +
Sbjct: 1777 TPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRA----------- 1825
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES-----RVQRS 368
T +P VP G + C + PG + + +
Sbjct: 1826 -------TMYPD----VPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874
Query: 369 RMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTP 428
+ P T P+ P P TTT++ + + + TG + P TP
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1934
Query: 429 ALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL--LRPPPPPAWL 486
+ G P+ P TP P G +P P + P P P
Sbjct: 1935 ----TPTGTQTPTT----TPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1985
Query: 487 KGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546
+ P + G P P+ P GTQ T P
Sbjct: 1986 QTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTP---TGTQTPTTTPIT 2040
Query: 547 PTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLAL 606
T T + + + +G+ + + P ++ P P P Q P P+ T
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTT-------PITTTTTVTPTPTPTG-TQTPTTTPITTTTTVT 2092
Query: 607 PPAPPSSCHQNTSGSFRRPES--PRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664
P P+ T+ + P P + +TP P ++ P P P G + P
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--PTPTPTGT-QTP 2149
Query: 665 ARGP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQ 722
P PTP + P I + V P
Sbjct: 2150 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2209
Query: 723 PPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLA 782
P +P T T T T T TTT TTT T P P
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269
Query: 783 KFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGP- 841
P P P +P + + + + TG T TT +P P
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPT 2326
Query: 842 PSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPP 899
P+G T + +P P+ + + +T+ P P P G TPT P
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTP 2383
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 112 bits (279), Expect = 4e-24
Identities = 154/652 (23%), Positives = 216/652 (33%), Gaps = 75/652 (11%)
Query: 318 PAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
PA T P P P+ P + P T P + +P
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--PKEPAPTTTKSAPTTPKEPAPT 265
Query: 378 ATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGR 437
T P P P P TT + +++ + EP P P TP
Sbjct: 266 TTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK-------- 315
Query: 438 LGPSAHSSRKPFLGAPAATPHLSLPPGPSSP--PPPPCPRLLRPPPP----PAWLKGPAC 491
P+ + ++P P + P P++P P P P+ P P P K PA
Sbjct: 316 -EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 492 RAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTT 551
+E P PAP PA T+ + T P P+PTT
Sbjct: 375 TTTKEPSPTT---------PKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTT 422
Query: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPP 611
+ + + +P P P P P+ P+P + P P PAP
Sbjct: 423 TKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAP- 476
Query: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPE-VGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670
T+ P +P+ P TPE + P P P P+ + P E P
Sbjct: 477 ------TTPKETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528
Query: 671 FDFPPTPLEDQFEEPAE-FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF 729
P TP P E P A +E G AP LKEP
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPA 587
Query: 730 ASL-QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS 788
+ + P P + APTTT + T TT T K P P P P +
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 789 QP----QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844
P +P P P PA K LA +G + S +P P + +P P
Sbjct: 648 APTTLKEPAPTTPKKPAP--KELAPTTT------KGPTSTTSDKPAPTTPKETAPTTPKE 699
Query: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE-------EPVPGPM--TP 895
P AP+ +P P+ S S +T+ P + E EP P + +P
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759
Query: 896 TQPPPPLSLPPARSESEVLEEISRACETLVERVGRSA--TDPADPVDTAEPA 945
+P P + PA ++ E+ + A + ER R+ T A P T E A
Sbjct: 760 KEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETA 808
Score = 104 bits (259), Expect = 8e-22
Identities = 174/752 (23%), Positives = 243/752 (32%), Gaps = 135/752 (17%)
Query: 337 PGPRPPGAES------HGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP 390
P P+PP + +G T P S + ++V S SP TTA P P
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV-------STSPKITTA----KPINP 126
Query: 391 -PGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPF 449
P LP + +S +S + VE T E + + S +
Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186
Query: 450 LGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGT 508
L A T + P P + P L P P P K PA +E
Sbjct: 187 L---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE------------ 231
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P P + P + T P TP P +++ + + PA
Sbjct: 232 -----PTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 281
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ P P +S P+ P+P + P P PAP + + P
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP---------KEPTPT 328
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
P+ P T E P P P AP+ P + PA P TP +EPA
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--------PTTP-----KEPAP- 374
Query: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPA 748
+ KE +P P KEP +P T +APTTT
Sbjct: 375 ----------------TTTKEP---------SPTTP-KEP-----APTTTKSAPTTTKEP 403
Query: 749 VAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPSQP-QPPPPPPPSPASLLK 805
TT + TT + K+P P P P P K P P+ P +P P P PA
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 806 SLASVLEGQKYCYRGTGAAVSTRPGPL-PTT--QYSPGPPSGATALPPTSAAPSAQGSPQ 862
+ ++ T P L PTT + +P P P AP+ P
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARS---ESEVLEEISR 919
P+ +T P A +E P P TP +P P PA + E+
Sbjct: 524 PTTPEEPAPTT---PKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578
Query: 920 ACETLVERVGRSATDPAD----PVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR 975
A TL E + PA P T EP + ++ P G+
Sbjct: 579 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP-----------TTPKGTAPTT 627
Query: 976 QKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
KE + A G P + A PK+ + + L + +K
Sbjct: 628 PKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPA 685
Query: 1036 PDLGGASKAKPPTAPAP--PSAPAPSAQPTPP 1065
P + P PAP P PAP+ TPP
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 717
Score = 99.4 bits (246), Expect = 3e-20
Identities = 145/589 (24%), Positives = 190/589 (32%), Gaps = 99/589 (16%)
Query: 235 SEQTGLPPGLPLPPPPLPPPPPPPPPPPP--PLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
+E T P L P P P P P P P P S P +P +T
Sbjct: 201 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 260
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGH--RLVPAAPPGPGPRPPG--AESHG 348
E AP +E + P PAP T P + P P P P P A +
Sbjct: 261 E---PAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP----PGLPGTTTSSSSSS 404
PA P + + + +P P AP +P P P TT +
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 405 SSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
++ EP+P P + PA P+ S PA T S P
Sbjct: 375 TTTK-----EPSPTTP-----KEPA----------PTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 465 PSSPPPP----PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP--P 518
P P P P P + P P K PA +E P P P P
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTT-PKKPAPTTPKE---------------PAPTTPKEP 458
Query: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPP---TPTTSSSNSNSGSHSSSPAGPVSFPPPP 575
P P + T T PT P TPTT + + +P P P
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 518
Query: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP 635
P P+P + P P A P++ + + + P P+ P
Sbjct: 519 ---------PEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAPTTPKEPAPTTPKEPAP 564
Query: 636 KTP-EVGPGPPPGPLS---KAPQPVPPGVGELPARGPRLFDFPPT----PLEDQFEEPAE 687
TP E P P G K P P P + P + PT P ++PA
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL-QSPFPTDTAPTTTA 746
P G A +E G AP LKEP + + P P + APTTT
Sbjct: 618 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 674
Query: 747 PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
T+TT+ T +E P P P K P P+ P+ PPP
Sbjct: 675 GP-----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 718
Score = 96.7 bits (239), Expect = 2e-19
Identities = 173/821 (21%), Positives = 259/821 (31%), Gaps = 132/821 (16%)
Query: 191 KRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPP 250
K P ++A +P P S P+ + +P + P P
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-----------------PAP 272
Query: 251 LPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP 310
P P P P P S P +P + P+ P+ P
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-------P 325
Query: 311 HPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
P PA T P P P P P P PA P + + +
Sbjct: 326 TPTTPKEPAPTTKEP----APTTPKEPAPTAPKK------PAPTTP-KEPAPTTPKEPAP 374
Query: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
++ P+ TT P AP+ P TT + +++ + EP+P TP
Sbjct: 375 TTTKEPSPTTPKEP-APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK- 432
Query: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P+ + +KP AP TP P P P P + P P K PA
Sbjct: 433 --------EPAPTTPKKP---AP-TTPKEPAPTTPKEPAPTTTKK-----PAPTTPKEPA 475
Query: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
+E + T P P P + P + T + TP TP P
Sbjct: 476 PTTPKETAPTTPKKL--TPTTPEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPA 531
Query: 551 TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP--- 607
++ + + + PA P P + +P P P P TL P
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 608 ----PAP----PSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGPGPPPGPLSKAPQPVPP 658
PAP P++ + TS + +P P+ + P TP E P P P P+ P
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
+ PA P TP ++PA P LA S ++
Sbjct: 650 TTLKEPA--------PTTP-----KKPA-----PKELAPTTTKGPTSTTSDKPAPTTPKE 691
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVA-VTTTTTTTTTTTATQEEEKKPPPALPP 777
AP P KEP A P T P T P + V+T TTT TT + ++ P
Sbjct: 692 TAPTTP-KEP-APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749
Query: 778 PPPLAKFPPPSQPQPPPPPPP----------------------SPASLLKSLASVLEGQK 815
P P A P +P P P +P + + E
Sbjct: 750 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 809
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSA------------QGSPQP 863
+ T + ++ + +T P T L T+ AP P+
Sbjct: 810 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACET 923
+A + + S + ++P P PT P ++P R + + + T
Sbjct: 870 TAKPKDRATNSKATTPKP----QKPTKAPKKPTSTKKPKTMPRVR-KPKTTPTPRKMTST 924
Query: 924 LVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGG 964
+ E S A T P + +L+ E+AGG
Sbjct: 925 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 965
Score = 85.5 bits (210), Expect = 4e-16
Identities = 133/592 (22%), Positives = 191/592 (32%), Gaps = 78/592 (13%)
Query: 512 PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP--- 568
PRP+ PP + S+ T T T TT+ S G ++ A
Sbjct: 126 PRPSLPPN-------SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 178
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ LA + L +P A+ P L P P + + + + + +P
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGP----ALTTPKEPTPTTPKEPASTTPKEPTP 234
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAP----QPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
S P TP+ P P AP +P P E P+ P P +
Sbjct: 235 TTIKSAPTTPKE---PAPTTTKSAPTTPKEPAPTTTKEPAPTTPK----EPAPTTTKEPA 287
Query: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT---DTA 741
P K P + KE AP P K + + P PT +
Sbjct: 288 PTTTKSAP------------TTPKEP---------APTTPKKPAPTTPKEPAPTTPKEPT 326
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPS---QPQPPPPP 796
PTT T TT KKP P P P P K P P+ +P P P
Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 797 PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP--PTSAA 854
P+P + + + E T +A +T P PTT P P + P P A
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ +T+ P +EP P T P P L P E
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 500
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
+ T E + + + P EPA + T + P KE A
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKS 1034
++ K++ P+ G A K P + + +L + +
Sbjct: 560 KEPAPTTP--------KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 610
Query: 1035 RPDLGGASKAKPPTAPAPPSAPAPSA----QPTPPSASVPGKKAREEAPGPP 1082
D + K TAP P PAP+ PT P + P +E AP P
Sbjct: 611 TCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTP 660
Score = 41.2 bits (95), Expect = 0.009
Identities = 83/425 (19%), Positives = 133/425 (31%), Gaps = 62/425 (14%)
Query: 708 KEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
K+ ++ + + P+PP+ + S F T T+T V+T+ TT
Sbjct: 67 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN- 125
Query: 766 EEEKKPPPALPPPPPLAK---------------------FPPPSQPQPPPPPPPSPASLL 804
P P+LPP +K + + S+
Sbjct: 126 -----PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 180
Query: 805 KSLASVL-EGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-----PSGATALPPT----SAA 854
K+ A L K + T A +T GP TT P P P+ T PT +A
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ + S+ + +E P P TP +P P + PA + ++
Sbjct: 241 PTTPKEPAPTTTKSAPTT------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294
Query: 915 EEISRACETLVERVGR-------SATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAA 967
+ + + T P +P T + T + P KE A
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 354
Query: 968 VSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVP---KEKSRRVLGNLDLQ 1024
++ K+ P+E P KE + +
Sbjct: 355 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 1025 SEEIQGREKSRPDLGGASKAKPPT----APAPPSAPAPSA--QPTPPSASVPGKKA-REE 1077
+E P + P T AP P PAP+ +P P + P +E
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 1078 APGPP 1082
AP P
Sbjct: 475 APTTP 479
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 112 bits (279), Expect = 4e-24
Identities = 154/652 (23%), Positives = 216/652 (33%), Gaps = 75/652 (11%)
Query: 318 PAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
PA T P P P+ P + P T P + +P
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--PKEPAPTTTKSAPTTPKEPAPT 306
Query: 378 ATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGR 437
T P P P P TT + +++ + EP P P TP
Sbjct: 307 TTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK-------- 356
Query: 438 LGPSAHSSRKPFLGAPAATPHLSLPPGPSSP--PPPPCPRLLRPPPP----PAWLKGPAC 491
P+ + ++P P + P P++P P P P+ P P P K PA
Sbjct: 357 -EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 492 RAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTT 551
+E P PAP PA T+ + T P P+PTT
Sbjct: 416 TTTKEPSPTT---------PKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTT 463
Query: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPP 611
+ + + +P P P P P+ P+P + P P PAP
Sbjct: 464 TKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAP- 517
Query: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPE-VGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670
T+ P +P+ P TPE + P P P P+ + P E P
Sbjct: 518 ------TTPKETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569
Query: 671 FDFPPTPLEDQFEEPAE-FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF 729
P TP P E P A +E G AP LKEP
Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPA 628
Query: 730 ASL-QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS 788
+ + P P + APTTT + T TT T K P P P P +
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 789 QP----QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844
P +P P P PA K LA +G + S +P P + +P P
Sbjct: 689 APTTLKEPAPTTPKKPAP--KELAPTTT------KGPTSTTSDKPAPTTPKETAPTTPKE 740
Query: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE-------EPVPGPM--TP 895
P AP+ +P P+ S S +T+ P + E EP P + +P
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800
Query: 896 TQPPPPLSLPPARSESEVLEEISRACETLVERVGRSA--TDPADPVDTAEPA 945
+P P + PA ++ E+ + A + ER R+ T A P T E A
Sbjct: 801 KEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETA 849
Score = 104 bits (259), Expect = 8e-22
Identities = 174/752 (23%), Positives = 243/752 (32%), Gaps = 135/752 (17%)
Query: 337 PGPRPPGAES------HGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP 390
P P+PP + +G T P S + ++V S SP TTA P P
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV-------STSPKITTA----KPINP 167
Query: 391 -PGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPF 449
P LP + +S +S + VE T E + + S +
Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 227
Query: 450 LGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGT 508
L A T + P P + P L P P P K PA +E
Sbjct: 228 L---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE------------ 272
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P P + P + T P TP P +++ + + PA
Sbjct: 273 -----PTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 322
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ P P +S P+ P+P + P P PAP + + P
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP---------KEPTPT 369
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
P+ P T E P P P AP+ P + PA P TP +EPA
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--------PTTP-----KEPAP- 415
Query: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPA 748
+ KE +P P KEP +P T +APTTT
Sbjct: 416 ----------------TTTKEP---------SPTTP-KEP-----APTTTKSAPTTTKEP 444
Query: 749 VAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPSQP-QPPPPPPPSPASLLK 805
TT + TT + K+P P P P P K P P+ P +P P P PA
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 806 SLASVLEGQKYCYRGTGAAVSTRPGPL-PTT--QYSPGPPSGATALPPTSAAPSAQGSPQ 862
+ ++ T P L PTT + +P P P AP+ P
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARS---ESEVLEEISR 919
P+ +T P A +E P P TP +P P PA + E+
Sbjct: 565 PTTPEEPAPTT---PKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 920 ACETLVERVGRSATDPAD----PVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR 975
A TL E + PA P T EP + ++ P G+
Sbjct: 620 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP-----------TTPKGTAPTT 668
Query: 976 QKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
KE + A G P + A PK+ + + L + +K
Sbjct: 669 PKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPA 726
Query: 1036 PDLGGASKAKPPTAPAP--PSAPAPSAQPTPP 1065
P + P PAP P PAP+ TPP
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 758
Score = 99.4 bits (246), Expect = 3e-20
Identities = 145/589 (24%), Positives = 190/589 (32%), Gaps = 99/589 (16%)
Query: 235 SEQTGLPPGLPLPPPPLPPPPPPPPPPPP--PLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
+E T P L P P P P P P P P S P +P +T
Sbjct: 242 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 301
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGH--RLVPAAPPGPGPRPPG--AESHG 348
E AP +E + P PAP T P + P P P P P A +
Sbjct: 302 E---PAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP----PGLPGTTTSSSSSS 404
PA P + + + +P P AP +P P P TT +
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 405 SSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
++ EP+P P + PA P+ S PA T S P
Sbjct: 416 TTTK-----EPSPTTP-----KEPA----------PTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 465 PSSPPPP----PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP--P 518
P P P P P + P P K PA +E P P P P
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTT-PKKPAPTTPKE---------------PAPTTPKEP 499
Query: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPP---TPTTSSSNSNSGSHSSSPAGPVSFPPPP 575
P P + T T PT P TPTT + + +P P P
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP 635
P P+P + P P A P++ + + + P P+ P
Sbjct: 560 ---------PEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAPTTPKEPAPTTPKEPAP 605
Query: 636 KTP-EVGPGPPPGPLS---KAPQPVPPGVGELPARGPRLFDFPPT----PLEDQFEEPAE 687
TP E P P G K P P P + P + PT P ++PA
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL-QSPFPTDTAPTTTA 746
P G A +E G AP LKEP + + P P + APTTT
Sbjct: 659 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 715
Query: 747 PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
T+TT+ T +E P P P K P P+ P+ PPP
Sbjct: 716 GP-----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 759
Score = 96.7 bits (239), Expect = 2e-19
Identities = 173/821 (21%), Positives = 259/821 (31%), Gaps = 132/821 (16%)
Query: 191 KRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPP 250
K P ++A +P P S P+ + +P + P P
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-----------------PAP 313
Query: 251 LPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP 310
P P P P P S P +P + P+ P+ P
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-------P 366
Query: 311 HPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
P PA T P P P P P P PA P + + +
Sbjct: 367 TPTTPKEPAPTTKEP----APTTPKEPAPTAPKK------PAPTTP-KEPAPTTPKEPAP 415
Query: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
++ P+ TT P AP+ P TT + +++ + EP+P TP
Sbjct: 416 TTTKEPSPTTPKEP-APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK- 473
Query: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P+ + +KP AP TP P P P P + P P K PA
Sbjct: 474 --------EPAPTTPKKP---AP-TTPKEPAPTTPKEPAPTTTKK-----PAPTTPKEPA 516
Query: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
+E + T P P P + P + T + TP TP P
Sbjct: 517 PTTPKETAPTTPKKL--TPTTPEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPA 572
Query: 551 TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP--- 607
++ + + + PA P P + +P P P P TL P
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 608 ----PAP----PSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGPGPPPGPLSKAPQPVPP 658
PAP P++ + TS + +P P+ + P TP E P P P P+ P
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
+ PA P TP ++PA P LA S ++
Sbjct: 691 TTLKEPA--------PTTP-----KKPA-----PKELAPTTTKGPTSTTSDKPAPTTPKE 732
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVA-VTTTTTTTTTTTATQEEEKKPPPALPP 777
AP P KEP A P T P T P + V+T TTT TT + ++ P
Sbjct: 733 TAPTTP-KEP-APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790
Query: 778 PPPLAKFPPPSQPQPPPPPPP----------------------SPASLLKSLASVLEGQK 815
P P A P +P P P +P + + E
Sbjct: 791 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 850
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSA------------QGSPQP 863
+ T + ++ + +T P T L T+ AP P+
Sbjct: 851 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACET 923
+A + + S + ++P P PT P ++P R + + + T
Sbjct: 911 TAKPKDRATNSKATTPKP----QKPTKAPKKPTSTKKPKTMPRVR-KPKTTPTPRKMTST 965
Query: 924 LVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGG 964
+ E S A T P + +L+ E+AGG
Sbjct: 966 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1006
Score = 85.5 bits (210), Expect = 4e-16
Identities = 133/592 (22%), Positives = 191/592 (32%), Gaps = 78/592 (13%)
Query: 512 PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP--- 568
PRP+ PP + S+ T T T TT+ S G ++ A
Sbjct: 167 PRPSLPPN-------SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 219
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ LA + L +P A+ P L P P + + + + + +P
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGP----ALTTPKEPTPTTPKEPASTTPKEPTP 275
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAP----QPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
S P TP+ P P AP +P P E P+ P P +
Sbjct: 276 TTIKSAPTTPKE---PAPTTTKSAPTTPKEPAPTTTKEPAPTTPK----EPAPTTTKEPA 328
Query: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT---DTA 741
P K P + KE AP P K + + P PT +
Sbjct: 329 PTTTKSAP------------TTPKEP---------APTTPKKPAPTTPKEPAPTTPKEPT 367
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPS---QPQPPPPP 796
PTT T TT KKP P P P P K P P+ +P P P
Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 797 PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP--PTSAA 854
P+P + + + E T +A +T P PTT P P + P P A
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ +T+ P +EP P T P P L P E
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 541
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
+ T E + + + P EPA + T + P KE A
Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKS 1034
++ K++ P+ G A K P + + +L + +
Sbjct: 601 KEPAPTTP--------KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 651
Query: 1035 RPDLGGASKAKPPTAPAPPSAPAPSA----QPTPPSASVPGKKAREEAPGPP 1082
D + K TAP P PAP+ PT P + P +E AP P
Sbjct: 652 TCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTP 701
Score = 41.2 bits (95), Expect = 0.009
Identities = 83/425 (19%), Positives = 133/425 (31%), Gaps = 62/425 (14%)
Query: 708 KEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
K+ ++ + + P+PP+ + S F T T+T V+T+ TT
Sbjct: 108 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN- 166
Query: 766 EEEKKPPPALPPPPPLAK---------------------FPPPSQPQPPPPPPPSPASLL 804
P P+LPP +K + + S+
Sbjct: 167 -----PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 221
Query: 805 KSLASVL-EGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-----PSGATALPPT----SAA 854
K+ A L K + T A +T GP TT P P P+ T PT +A
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ + S+ + +E P P TP +P P + PA + ++
Sbjct: 282 PTTPKEPAPTTTKSAPTT------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335
Query: 915 EEISRACETLVERVGR-------SATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAA 967
+ + + T P +P T + T + P KE A
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 395
Query: 968 VSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVP---KEKSRRVLGNLDLQ 1024
++ K+ P+E P KE + +
Sbjct: 396 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 1025 SEEIQGREKSRPDLGGASKAKPPT----APAPPSAPAPSA--QPTPPSASVPGKKA-REE 1077
+E P + P T AP P PAP+ +P P + P +E
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 1078 APGPP 1082
AP P
Sbjct: 516 APTTP 520
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 112 bits (279), Expect = 4e-24
Identities = 154/652 (23%), Positives = 216/652 (33%), Gaps = 75/652 (11%)
Query: 318 PAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
PA T P P P+ P + P T P + +P
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--PKEPAPTTTKSAPTTPKEPAPT 358
Query: 378 ATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGR 437
T P P P P TT + +++ + EP P P TP
Sbjct: 359 TTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK-------- 408
Query: 438 LGPSAHSSRKPFLGAPAATPHLSLPPGPSSP--PPPPCPRLLRPPPP----PAWLKGPAC 491
P+ + ++P P + P P++P P P P+ P P P K PA
Sbjct: 409 -EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467
Query: 492 RAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTT 551
+E P PAP PA T+ + T P P+PTT
Sbjct: 468 TTTKEPSPTT---------PKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTT 515
Query: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPP 611
+ + + +P P P P P+ P+P + P P PAP
Sbjct: 516 TKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAP- 569
Query: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPE-VGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670
T+ P +P+ P TPE + P P P P+ + P E P
Sbjct: 570 ------TTPKETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 671 FDFPPTPLEDQFEEPAE-FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF 729
P TP P E P A +E G AP LKEP
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPA 680
Query: 730 ASL-QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS 788
+ + P P + APTTT + T TT T K P P P P +
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 789 QP----QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844
P +P P P PA K LA +G + S +P P + +P P
Sbjct: 741 APTTLKEPAPTTPKKPAP--KELAPTTT------KGPTSTTSDKPAPTTPKETAPTTPKE 792
Query: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE-------EPVPGPM--TP 895
P AP+ +P P+ S S +T+ P + E EP P + +P
Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852
Query: 896 TQPPPPLSLPPARSESEVLEEISRACETLVERVGRSA--TDPADPVDTAEPA 945
+P P + PA ++ E+ + A + ER R+ T A P T E A
Sbjct: 853 KEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETA 901
Score = 104 bits (259), Expect = 8e-22
Identities = 174/752 (23%), Positives = 243/752 (32%), Gaps = 135/752 (17%)
Query: 337 PGPRPPGAES------HGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP 390
P P+PP + +G T P S + ++V S SP TTA P P
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV-------STSPKITTA----KPINP 219
Query: 391 -PGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPF 449
P LP + +S +S + VE T E + + S +
Sbjct: 220 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 279
Query: 450 LGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGT 508
L A T + P P + P L P P P K PA +E
Sbjct: 280 L---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE------------ 324
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P P + P + T P TP P +++ + + PA
Sbjct: 325 -----PTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 374
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ P P +S P+ P+P + P P PAP + + P
Sbjct: 375 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP---------KEPTPT 421
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
P+ P T E P P P AP+ P + PA P TP +EPA
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--------PTTP-----KEPAP- 467
Query: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPA 748
+ KE +P P KEP +P T +APTTT
Sbjct: 468 ----------------TTTKEP---------SPTTP-KEP-----APTTTKSAPTTTKEP 496
Query: 749 VAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPSQP-QPPPPPPPSPASLLK 805
TT + TT + K+P P P P P K P P+ P +P P P PA
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556
Query: 806 SLASVLEGQKYCYRGTGAAVSTRPGPL-PTT--QYSPGPPSGATALPPTSAAPSAQGSPQ 862
+ ++ T P L PTT + +P P P AP+ P
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARS---ESEVLEEISR 919
P+ +T P A +E P P TP +P P PA + E+
Sbjct: 617 PTTPEEPAPTT---PKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671
Query: 920 ACETLVERVGRSATDPAD----PVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR 975
A TL E + PA P T EP + ++ P G+
Sbjct: 672 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP-----------TTPKGTAPTT 720
Query: 976 QKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
KE + A G P + A PK+ + + L + +K
Sbjct: 721 PKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 1036 PDLGGASKAKPPTAPAP--PSAPAPSAQPTPP 1065
P + P PAP P PAP+ TPP
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 810
Score = 99.4 bits (246), Expect = 3e-20
Identities = 145/589 (24%), Positives = 190/589 (32%), Gaps = 99/589 (16%)
Query: 235 SEQTGLPPGLPLPPPPLPPPPPPPPPPPP--PLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
+E T P L P P P P P P P P S P +P +T
Sbjct: 294 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGH--RLVPAAPPGPGPRPPG--AESHG 348
E AP +E + P PAP T P + P P P P P A +
Sbjct: 354 E---PAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP----PGLPGTTTSSSSSS 404
PA P + + + +P P AP +P P P TT +
Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467
Query: 405 SSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
++ EP+P P + PA P+ S PA T S P
Sbjct: 468 TTTK-----EPSPTTP-----KEPA----------PTTTKSAPTTTKEPAPTTTKSAPTT 507
Query: 465 PSSPPPP----PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP--P 518
P P P P P + P P K PA +E P P P P
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTT-PKKPAPTTPKE---------------PAPTTPKEP 551
Query: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPP---TPTTSSSNSNSGSHSSSPAGPVSFPPPP 575
P P + T T PT P TPTT + + +P P P
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 611
Query: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP 635
P P+P + P P A P++ + + + P P+ P
Sbjct: 612 ---------PEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAPTTPKEPAPTTPKEPAP 657
Query: 636 KTP-EVGPGPPPGPLS---KAPQPVPPGVGELPARGPRLFDFPPT----PLEDQFEEPAE 687
TP E P P G K P P P + P + PT P ++PA
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL-QSPFPTDTAPTTTA 746
P G A +E G AP LKEP + + P P + APTTT
Sbjct: 711 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 767
Query: 747 PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
T+TT+ T +E P P P K P P+ P+ PPP
Sbjct: 768 GP-----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 811
Score = 96.7 bits (239), Expect = 2e-19
Identities = 173/821 (21%), Positives = 259/821 (31%), Gaps = 132/821 (16%)
Query: 191 KRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPP 250
K P ++A +P P S P+ + +P + P P
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-----------------PAP 365
Query: 251 LPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP 310
P P P P P S P +P + P+ P+ P
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-------P 418
Query: 311 HPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
P PA T P P P P P P PA P + + +
Sbjct: 419 TPTTPKEPAPTTKEP----APTTPKEPAPTAPKK------PAPTTP-KEPAPTTPKEPAP 467
Query: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
++ P+ TT P AP+ P TT + +++ + EP+P TP
Sbjct: 468 TTTKEPSPTTPKEP-APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK- 525
Query: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P+ + +KP AP TP P P P P + P P K PA
Sbjct: 526 --------EPAPTTPKKP---AP-TTPKEPAPTTPKEPAPTTTKK-----PAPTTPKEPA 568
Query: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
+E + T P P P + P + T + TP TP P
Sbjct: 569 PTTPKETAPTTPKKL--TPTTPEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPA 624
Query: 551 TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP--- 607
++ + + + PA P P + +P P P P TL P
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 608 ----PAP----PSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGPGPPPGPLSKAPQPVPP 658
PAP P++ + TS + +P P+ + P TP E P P P P+ P
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
+ PA P TP ++PA P LA S ++
Sbjct: 743 TTLKEPA--------PTTP-----KKPA-----PKELAPTTTKGPTSTTSDKPAPTTPKE 784
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVA-VTTTTTTTTTTTATQEEEKKPPPALPP 777
AP P KEP A P T P T P + V+T TTT TT + ++ P
Sbjct: 785 TAPTTP-KEP-APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842
Query: 778 PPPLAKFPPPSQPQPPPPPPP----------------------SPASLLKSLASVLEGQK 815
P P A P +P P P +P + + E
Sbjct: 843 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 902
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSA------------QGSPQP 863
+ T + ++ + +T P T L T+ AP P+
Sbjct: 903 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACET 923
+A + + S + ++P P PT P ++P R + + + T
Sbjct: 963 TAKPKDRATNSKATTPKP----QKPTKAPKKPTSTKKPKTMPRVR-KPKTTPTPRKMTST 1017
Query: 924 LVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGG 964
+ E S A T P + +L+ E+AGG
Sbjct: 1018 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1058
Score = 85.5 bits (210), Expect = 4e-16
Identities = 133/592 (22%), Positives = 191/592 (32%), Gaps = 78/592 (13%)
Query: 512 PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP--- 568
PRP+ PP + S+ T T T TT+ S G ++ A
Sbjct: 219 PRPSLPPN-------SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 271
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ LA + L +P A+ P L P P + + + + + +P
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGP----ALTTPKEPTPTTPKEPASTTPKEPTP 327
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAP----QPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
S P TP+ P P AP +P P E P+ P P +
Sbjct: 328 TTIKSAPTTPKE---PAPTTTKSAPTTPKEPAPTTTKEPAPTTPK----EPAPTTTKEPA 380
Query: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT---DTA 741
P K P + KE AP P K + + P PT +
Sbjct: 381 PTTTKSAP------------TTPKEP---------APTTPKKPAPTTPKEPAPTTPKEPT 419
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPS---QPQPPPPP 796
PTT T TT KKP P P P P K P P+ +P P P
Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 797 PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP--PTSAA 854
P+P + + + E T +A +T P PTT P P + P P A
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ +T+ P +EP P T P P L P E
Sbjct: 537 PTTPKEPAPTTPKEPAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 593
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
+ T E + + + P EPA + T + P KE A
Sbjct: 594 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKS 1034
++ K++ P+ G A K P + + +L + +
Sbjct: 653 KEPAPTTP--------KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 703
Query: 1035 RPDLGGASKAKPPTAPAPPSAPAPSA----QPTPPSASVPGKKAREEAPGPP 1082
D + K TAP P PAP+ PT P + P +E AP P
Sbjct: 704 TCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTP 753
Score = 41.2 bits (95), Expect = 0.009
Identities = 83/425 (19%), Positives = 133/425 (31%), Gaps = 62/425 (14%)
Query: 708 KEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
K+ ++ + + P+PP+ + S F T T+T V+T+ TT
Sbjct: 160 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN- 218
Query: 766 EEEKKPPPALPPPPPLAK---------------------FPPPSQPQPPPPPPPSPASLL 804
P P+LPP +K + + S+
Sbjct: 219 -----PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 273
Query: 805 KSLASVL-EGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-----PSGATALPPT----SAA 854
K+ A L K + T A +T GP TT P P P+ T PT +A
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ + S+ + +E P P TP +P P + PA + ++
Sbjct: 334 PTTPKEPAPTTTKSAPTT------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387
Query: 915 EEISRACETLVERVGR-------SATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAA 967
+ + + T P +P T + T + P KE A
Sbjct: 388 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 447
Query: 968 VSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVP---KEKSRRVLGNLDLQ 1024
++ K+ P+E P KE + +
Sbjct: 448 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507
Query: 1025 SEEIQGREKSRPDLGGASKAKPPT----APAPPSAPAPSA--QPTPPSASVPGKKA-REE 1077
+E P + P T AP P PAP+ +P P + P +E
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 1078 APGPP 1082
AP P
Sbjct: 568 APTTP 572
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 112 bits (279), Expect = 4e-24
Identities = 154/652 (23%), Positives = 216/652 (33%), Gaps = 75/652 (11%)
Query: 318 PAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377
PA T P P P+ P + P T P + +P
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--PKEPAPTTTKSAPTTPKEPAPT 399
Query: 378 ATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGR 437
T P P P P TT + +++ + EP P P TP
Sbjct: 400 TTKEPAPTTPKEPA--PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK-------- 449
Query: 438 LGPSAHSSRKPFLGAPAATPHLSLPPGPSSP--PPPPCPRLLRPPPP----PAWLKGPAC 491
P+ + ++P P + P P++P P P P+ P P P K PA
Sbjct: 450 -EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508
Query: 492 RAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTT 551
+E P PAP PA T+ + T P P+PTT
Sbjct: 509 TTTKEPSPTT---------PKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTT 556
Query: 552 SSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPP 611
+ + + +P P P P P+ P+P + P P PAP
Sbjct: 557 TKEPAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE----PAP- 610
Query: 612 SSCHQNTSGSFRRPESPRPRVSFPKTPE-VGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670
T+ P +P+ P TPE + P P P P+ + P E P
Sbjct: 611 ------TTPKETAPTTPKKLT--PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 671 FDFPPTPLEDQFEEPAE-FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF 729
P TP P E P A +E G AP LKEP
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPA 721
Query: 730 ASL-QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS 788
+ + P P + APTTT + T TT T K P P P P +
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 789 QP----QPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSG 844
P +P P P PA K LA +G + S +P P + +P P
Sbjct: 782 APTTLKEPAPTTPKKPAP--KELAPTTT------KGPTSTTSDKPAPTTPKETAPTTPKE 833
Query: 845 ATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE-------EPVPGPM--TP 895
P AP+ +P P+ S S +T+ P + E EP P + +P
Sbjct: 834 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893
Query: 896 TQPPPPLSLPPARSESEVLEEISRACETLVERVGRSA--TDPADPVDTAEPA 945
+P P + PA ++ E+ + A + ER R+ T A P T E A
Sbjct: 894 KEPGVPTTKTPAATKPEM---TTTAKDKTTERDLRTTPETTTAAPKMTKETA 942
Score = 104 bits (259), Expect = 8e-22
Identities = 174/752 (23%), Positives = 243/752 (32%), Gaps = 135/752 (17%)
Query: 337 PGPRPPGAES------HGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP 390
P P+PP + +G T P S + ++V S SP TTA P P
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKV-------STSPKITTA----KPINP 260
Query: 391 -PGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPF 449
P LP + +S +S + VE T E + + S +
Sbjct: 261 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 320
Query: 450 LGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP-PAWLKGPACRAAREDGEILEELFFGT 508
L A T + P P + P L P P P K PA +E
Sbjct: 321 L---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE------------ 365
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
P P + P + T P TP P +++ + + PA
Sbjct: 366 -----PTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPT 415
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ P P +S P+ P+P + P P PAP + + P
Sbjct: 416 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE----PAPTTP---------KEPTPT 462
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
P+ P T E P P P AP+ P + PA P TP +EPA
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA--------PTTP-----KEPAP- 508
Query: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPA 748
+ KE +P P KEP +P T +APTTT
Sbjct: 509 ----------------TTTKEP---------SPTTP-KEP-----APTTTKSAPTTTKEP 537
Query: 749 VAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPSQP-QPPPPPPPSPASLLK 805
TT + TT + K+P P P P P K P P+ P +P P P PA
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597
Query: 806 SLASVLEGQKYCYRGTGAAVSTRPGPL-PTT--QYSPGPPSGATALPPTSAAPSAQGSPQ 862
+ ++ T P L PTT + +P P P AP+ P
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARS---ESEVLEEISR 919
P+ +T P A +E P P TP +P P PA + E+
Sbjct: 658 PTTPEEPAPTT---PKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712
Query: 920 ACETLVERVGRSATDPAD----PVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR 975
A TL E + PA P T EP + ++ P G+
Sbjct: 713 APTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP-----------TTPKGTAPTT 761
Query: 976 QKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
KE + A G P + A PK+ + + L + +K
Sbjct: 762 PKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPT-TPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 1036 PDLGGASKAKPPTAPAP--PSAPAPSAQPTPP 1065
P + P PAP P PAP+ TPP
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPP 851
Score = 99.4 bits (246), Expect = 3e-20
Identities = 145/589 (24%), Positives = 190/589 (32%), Gaps = 99/589 (16%)
Query: 235 SEQTGLPPGLPLPPPPLPPPPPPPPPPPP--PLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
+E T P L P P P P P P P P S P +P +T
Sbjct: 335 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394
Query: 293 ERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGH--RLVPAAPPGPGPRPPG--AESHG 348
E AP +E + P PAP T P + P P P P P A +
Sbjct: 395 E---PAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRP----PGLPGTTTSSSSSS 404
PA P + + + +P P AP +P P P TT +
Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508
Query: 405 SSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG 464
++ EP+P P + PA P+ S PA T S P
Sbjct: 509 TTTK-----EPSPTTP-----KEPA----------PTTTKSAPTTTKEPAPTTTKSAPTT 548
Query: 465 PSSPPPP----PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPP--P 518
P P P P P + P P K PA +E P P P P
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTT-PKKPAPTTPKE---------------PAPTTPKEP 592
Query: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPP---TPTTSSSNSNSGSHSSSPAGPVSFPPPP 575
P P + T T PT P TPTT + + +P P P
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 652
Query: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP 635
P P+P + P P A P++ + + + P P+ P
Sbjct: 653 ---------PEEPTPTTPEEPAPTTPKAAA-----PNTPKEPAPTTPKEPAPTTPKEPAP 698
Query: 636 KTP-EVGPGPPPGPLS---KAPQPVPPGVGELPARGPRLFDFPPT----PLEDQFEEPAE 687
TP E P P G K P P P + P + PT P ++PA
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTP-------KKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL-QSPFPTDTAPTTTA 746
P G A +E G AP LKEP + + P P + APTTT
Sbjct: 752 --TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 808
Query: 747 PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
T+TT+ T +E P P P K P P+ P+ PPP
Sbjct: 809 GP-----TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPP 852
Score = 96.7 bits (239), Expect = 2e-19
Identities = 173/821 (21%), Positives = 259/821 (31%), Gaps = 132/821 (16%)
Query: 191 KRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPP 250
K P ++A +P P S P+ + +P + P P
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE-----------------PAP 406
Query: 251 LPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLP 310
P P P P P S P +P + P+ P+ P
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE-------P 459
Query: 311 HPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
P PA T P P P P P P PA P + + +
Sbjct: 460 TPTTPKEPAPTTKEP----APTTPKEPAPTAPKK------PAPTTP-KEPAPTTPKEPAP 508
Query: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
++ P+ TT P AP+ P TT + +++ + EP+P TP
Sbjct: 509 TTTKEPSPTTPKEP-APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK- 566
Query: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
P+ + +KP AP TP P P P P + P P K PA
Sbjct: 567 --------EPAPTTPKKP---AP-TTPKEPAPTTPKEPAPTTTKK-----PAPTTPKEPA 609
Query: 491 CRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPT 550
+E + T P P P + P + T + TP TP P
Sbjct: 610 PTTPKETAPTTPKKL--TPTTPEKLAPTTPEKPAPTTP--EELAPTTPEEPTPTTPEEPA 665
Query: 551 TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP--- 607
++ + + + PA P P + +P P P P TL P
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPK--EPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 608 ----PAP----PSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGPGPPPGPLSKAPQPVPP 658
PAP P++ + TS + +P P+ + P TP E P P P P+ P
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
+ PA P TP ++PA P LA S ++
Sbjct: 784 TTLKEPA--------PTTP-----KKPA-----PKELAPTTTKGPTSTTSDKPAPTTPKE 825
Query: 719 VAPQPPLKEPFASLQSPFPTDTAPTTTAPAVA-VTTTTTTTTTTTATQEEEKKPPPALPP 777
AP P KEP A P T P T P + V+T TTT TT + ++ P
Sbjct: 826 TAPTTP-KEP-APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883
Query: 778 PPPLAKFPPPSQPQPPPPPPP----------------------SPASLLKSLASVLEGQK 815
P P A P +P P P +P + + E
Sbjct: 884 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETAT 943
Query: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSA------------QGSPQP 863
+ T + ++ + +T P T L T+ AP P+
Sbjct: 944 TTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 1003
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACET 923
+A + + S + ++P P PT P ++P R + + + T
Sbjct: 1004 TAKPKDRATNSKATTPKP----QKPTKAPKKPTSTKKPKTMPRVR-KPKTTPTPRKMTST 1058
Query: 924 LVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGG 964
+ E S A T P + +L+ E+AGG
Sbjct: 1059 MPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGG 1099
Score = 85.5 bits (210), Expect = 4e-16
Identities = 133/592 (22%), Positives = 191/592 (32%), Gaps = 78/592 (13%)
Query: 512 PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP--- 568
PRP+ PP + S+ T T T TT+ S G ++ A
Sbjct: 260 PRPSLPPN-------SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 312
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ LA + L +P A+ P L P P + + + + + +P
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGP----ALTTPKEPTPTTPKEPASTTPKEPTP 368
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKAP----QPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
S P TP+ P P AP +P P E P+ P P +
Sbjct: 369 TTIKSAPTTPKE---PAPTTTKSAPTTPKEPAPTTTKEPAPTTPK----EPAPTTTKEPA 421
Query: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT---DTA 741
P K P + KE AP P K + + P PT +
Sbjct: 422 PTTTKSAP------------TTPKEP---------APTTPKKPAPTTPKEPAPTTPKEPT 460
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP--PPPPLAKFPPPS---QPQPPPPP 796
PTT T TT KKP P P P P K P P+ +P P P
Sbjct: 461 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 797 PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP--PTSAA 854
P+P + + + E T +A +T P PTT P P + P P A
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ +T+ P +EP P T P P L P E
Sbjct: 578 PTTPKEPAPTTPKEPAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 634
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
+ T E + + + P EPA + T + P KE A
Sbjct: 635 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT-TPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKS 1034
++ K++ P+ G A K P + + +L + +
Sbjct: 694 KEPAPTTP--------KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 744
Query: 1035 RPDLGGASKAKPPTAPAPPSAPAPSA----QPTPPSASVPGKKAREEAPGPP 1082
D + K TAP P PAP+ PT P + P +E AP P
Sbjct: 745 TCDKPAPTTPKG-TAPTTPKEPAPTTPKEPAPTTPKGTAP-TTLKEPAPTTP 794
Score = 41.2 bits (95), Expect = 0.009
Identities = 83/425 (19%), Positives = 133/425 (31%), Gaps = 62/425 (14%)
Query: 708 KEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
K+ ++ + + P+PP+ + S F T T+T V+T+ TT
Sbjct: 201 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPIN- 259
Query: 766 EEEKKPPPALPPPPPLAK---------------------FPPPSQPQPPPPPPPSPASLL 804
P P+LPP +K + + S+
Sbjct: 260 -----PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 314
Query: 805 KSLASVL-EGQKYCYRGTGAAVSTRPGPLPTTQYSPGP-----PSGATALPPT----SAA 854
K+ A L K + T A +T GP TT P P P+ T PT +A
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
P+ P P+ + S+ + +E P P TP +P P + PA + ++
Sbjct: 375 PTTPKEPAPTTTKSAPTT------PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428
Query: 915 EEISRACETLVERVGR-------SATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAA 967
+ + + T P +P T + T + P KE A
Sbjct: 429 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 488
Query: 968 VSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVP---KEKSRRVLGNLDLQ 1024
++ K+ P+E P KE + +
Sbjct: 489 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548
Query: 1025 SEEIQGREKSRPDLGGASKAKPPT----APAPPSAPAPSA--QPTPPSASVPGKKA-REE 1077
+E P + P T AP P PAP+ +P P + P +E
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 1078 APGPP 1082
AP P
Sbjct: 609 APTTP 613
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 111 bits (278), Expect = 5e-24
Identities = 261/1167 (22%), Positives = 394/1167 (33%), Gaps = 236/1167 (20%)
Query: 228 KRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPP---PLP------GLATSPPFQLTK 278
K+++ EQ G P G+ PP PP P P P PL +++ P ++
Sbjct: 191 KKQKVVQKEQ-GKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 279 --PGLWSTLHGDAWGPE---------RKGSAPPERQEQ-------RHSLPHPYPYPAPAY 320
PG + G P+ R S P +Q + SLP P P
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 321 TAHPPGHRLVPAAPPG-----PGPRPPGAESHGCL-PATRPPGSDLRESRVQRSRMDSSV 374
T P PA PG PGP P A+ G P + PG+ + V
Sbjct: 310 TPGKP-----PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-----------VKPPV 353
Query: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSH 434
P TT P P P P T S SS G + + PG+ G Q P
Sbjct: 354 QPPGTTK-PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP 411
Query: 435 HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP---PAWLKGPAC 491
++G +++P L +PA P GP+ P ++ P P PA GP
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAP------GPTKTP-------VQQPGPGKIPAQQAGPGK 458
Query: 492 RAAREDGEILEELFFGTEGP---PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
+A++ G T+ P P PA PP P + G PP + S PP+
Sbjct: 459 TSAQQTGP--------TKPPSQLPGPAKPP-PQQPGPAKPPPQQ-----PGSAKPPSQQP 504
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
+T G SP P S PP S P + PSPA+ P
Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK--------------PS 550
Query: 609 APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGP 668
A S+ + +GS +P P P V P P P+ + P
Sbjct: 551 AQQSTKPVSQTGS-GKPLQP---------PTVSPSAKQPPSQGLPKTICPLCNT------ 594
Query: 669 RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
T L E A F + + + G P P L E
Sbjct: 595 -------TELLLHVPEKANFNTCTECQTTVCSL---------------CGFNPNPHLTEV 632
Query: 729 F------ASLQSPFPTDTAPTTTAPAVAVTT---TTTTTTTTTATQEEEKKPPPALPPPP 779
++ D AP ++P + T TTT+ + ++ Q ++ P P
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
Query: 780 PLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP 839
L+K P +P+ PPP P G+ +A + +P P + P
Sbjct: 693 DLSKAP---EPKKPPPLVKQPT----------------LHGSPSAKAKQP-PEADSLSKP 732
Query: 840 GPPSGATALPPTSAAPSAQGSP-QPS--------ASSSSQFSTSGGPWARERRAGEEPVP 890
PP + AP A P QP SSSS + P ++ + EE
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 891 GPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTE 950
P+ P S PP + + + + R A+D ++S +
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDS---------KAIPRPASDSKIISHPGPSSESKGQ 843
Query: 951 RLLPPAQAKEEAGGVAAVSGSCKRRQKEHQK-EHRRHRRACKDSVGRRPREGR---AKAK 1006
+ + P Q KEE K + K K + + + G RP G+ +
Sbjct: 844 KQVDPVQKKEEPK---------KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 1007 AKVPKEKSRRVLGNLDLQSEEIQGREKSRPD------LGGASKAKPPTAPAPPSAPAPSA 1060
+ P+E+SRR NL I KS+P G + + +
Sbjct: 895 SPKPQEQSRRFSLNLG----SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG 950
Query: 1061 QPTPPSASVPGKKARE-EAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFI 1119
QP P S S PG ++ AP P S+ +S + PP K +K E+ +
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---KSTGQAPPAPAKSIPVKKET---KAPA 1004
Query: 1120 ASEVEERRLRMADLTISHCAADVVRASRNAKVKGKFRESYLSPAQSVKPKINTE-EKLPR 1178
A ++E + + A V+ + K ++S A+ K + T+ EK P
Sbjct: 1005 AEKLEPKAEQ----------APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP- 1053
Query: 1179 EKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRL----NLGLFSTKTL 1234
K P E + P CT+ +N + + G + L + +T
Sbjct: 1054 -KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQ 1112
Query: 1235 VEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQE 1294
SG+ ++R PS + P ESS T + + QE E
Sbjct: 1113 RAISGQ-LGDIRKMPPAPSGPK----ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTE 1167
Query: 1295 EKESEDEESEEPDSTTGTPPSSAPDPK 1321
++ E+ +E S PP D K
Sbjct: 1168 AEKVILEKVKETLSMEKIPPMVTTDQK 1194
Score = 109 bits (273), Expect = 2e-23
Identities = 259/1189 (21%), Positives = 406/1189 (34%), Gaps = 195/1189 (16%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPP 254
P + ++PP+ QP P + G E PG + ++ +GL L P + PP
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP---PAQPSGLTKPLAQQPGTVKPP 352
Query: 255 PPPPPPPPPPLPGLA-TSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY 313
PP PP L PP Q T GS P ++
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQT------------------GSEKPSSEQ--------- 385
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P A PPG PA PGP +PP + P + PG S
Sbjct: 386 --PGPKALAQPPGVGKTPAQQPGPA-KPPTQQVGTPKPLAQQPGL-------------QS 429
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+ A P P +P +S+ TG +P +PG P +
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG--PTKPPSQLPGP---AKPPPQQP 484
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP-------PPPAWL 486
+ P S KP P +T PGP+ P P P +PP P A
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ-PGSTKPPSQQPGSAKPSAQQ 543
Query: 487 KGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546
PA +A++ + + + G +P PP + P A + PP+
Sbjct: 544 PSPAKPSAQQSTKPVSQ-----TGSGKPLQPPT------VSPSAKQ----------PPSQ 582
Query: 547 PTPTT---------------SSSNSNSGSH-SSSPAGPVSFPPPPYLARSIDPLPRPPSP 590
P T +N N+ + ++ F P P+L + L
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL------ 636
Query: 591 AQNPQDPPLVPLTLALPPAPPSSCHQN---TSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647
N Q + LA P+ P + T+ S SP+P+ + PK P
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK----DAAPKQ 692
Query: 648 PLSKAPQP--VPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDES 705
LSKAP+P PP V + G P D +PA K + S
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-------------EPS 739
Query: 706 IRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
+ E+++ QP + +P L S T P + V + TT +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV---QSQAEEKTTPPLK 796
Query: 766 EEEKKPPPALPPP-PPLAKFPPPSQPQPPPPPP----PSPASLLKSLASVLEGQKYCY-R 819
+ KP + PP ++ F + P+P P P+S K V QK +
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWA 879
+S +P P + SP PP T P+ Q SP+P S +FS + G
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT--VPTPQQSPKPQ-EQSRRFSLNLGSIT 913
Query: 880 RERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPV 939
++ PT P ++ + + + S T + S + P P+
Sbjct: 914 DAPKS---------QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPM 964
Query: 940 DTA-----EPADSGTER---LLPPAQA-----KEEAGGVAAVSGSCKRRQKEHQKEHRRH 986
A P G + PPA A K+E AA K Q K
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 987 RR--ACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKA 1044
++ KDS +A K+ EKS + L E+ K P+ ++
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKL--EKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 1045 KPPTAPAPPSAPAPSAQ----------PTPPSASVPGKKAREEAPGPPGVSRADM-LKLR 1093
K P P T + S R+ P P G + M +
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 1094 SLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKG 1153
S S+ +++L+K +E + +E E+ L T+S + + + +
Sbjct: 1143 SSSQKTAVPPQVKLVK----KQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198
Query: 1154 KFRESYLSPAQSVKPKINTEEKLPRE-KLNPPTPSIYLESKRDAFSPVLLQFCTDPRNP- 1211
K + S Q KP LP E KL P I E K+ P+L + P +
Sbjct: 1199 KLEKDKASALQEKKP-------LPEEKKLIPEEEKIRSEEKK----PLLEEKKPTPEDKK 1247
Query: 1212 -ITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRT--QVQQPSDENWDL-TGTRQIWP 1267
+ + A + + L S + E E V +T + +QP + L +GT Q P
Sbjct: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
Query: 1268 CESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSS 1316
E ++ TI + Q ++ + ++ KE ++E ++ D+++ P S
Sbjct: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Score = 62.4 bits (150), Expect = 4e-09
Identities = 70/223 (31%), Positives = 84/223 (37%), Gaps = 27/223 (12%)
Query: 217 PSGEEGLS--PGGKRR--RGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSP 272
PSG +S P R R + + + PP P PPPP PPPPPPPPPPPPPLP +
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPP--PPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 273 PFQLTKPGLWSTLHGDAWGPERKGSAPPERQE--QRHSLP-------HPYPYPAPAYTAH 323
P L K L P E + + LP P P P P ++
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP-PKPSSI 2493
Query: 324 PPG----HRLVPAAPP-GPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAA 378
P G HR P+ PP P P P LP T +D+ S S
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQ------LPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 379 TTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPG 421
T+A P P + SS S S T V P PG
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG 2590
Score = 54.7 bits (130), Expect = 7e-07
Identities = 79/337 (23%), Positives = 113/337 (33%), Gaps = 29/337 (8%)
Query: 529 PASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP 588
PAS+ G+ + P P P SS+ + + P P PPPP PLP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 589 SPAQNPQDPPLVPLTLALP-----PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG 643
SP P P LT+A P P + T+ R P R+ P V P
Sbjct: 2432 SP--KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 644 PPPGP----LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIM 699
P P + P+P P + P P P Q +P + P GL+
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPV-------IPQLPTTTQ--KPTDIHPKPTGLSLTS 2540
Query: 700 KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTT 759
M + + + +P PL P ++ SP + + T V +T + T
Sbjct: 2541 SMTLNLVTSADYKLP-----SPTSPL-SPHSNKSSP---RFSKSLTETYVVITLPSEPGT 2591
Query: 760 TTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYR 819
T ++ + P P L P PP P S ++ Q +
Sbjct: 2592 PTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT 2651
Query: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856
A S + P TQ+ S S APS
Sbjct: 2652 PVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPS 2688
Score = 53.1 bits (126), Expect = 2e-06
Identities = 92/361 (25%), Positives = 129/361 (35%), Gaps = 51/361 (14%)
Query: 757 TTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQP--QPPPPPPPSPASLLKSLASVL-EG 813
TT Q+E+ KP + PPL + PP P Q P P KS++S E
Sbjct: 189 TTKKQKVVQKEQGKPEGII--KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
Query: 814 QKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQG-SPQPSASSSS--- 869
K GTG + P P T ++ P + P T A +G S +PS S S
Sbjct: 247 IKSQPPGTGKPIQ-GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 870 -QFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERV 928
Q T G P A ++ E+ PGP P P L+ P A+ V + T
Sbjct: 306 IQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT----- 359
Query: 929 GRSATDPADPVDTAEPADSGTERLLP-------------------PAQAKEEAGGVAAVS 969
PA P+ A+P T P PAQ A
Sbjct: 360 ----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 970 GSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQ 1029
G+ K ++ + + ++P G+ A+ P + S + G S ++
Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS-QLP 474
Query: 1030 GREKSRPDLGGASKAKP--PTAPAPPSAPAPSAQPTP-------PSASVPGK-KAREEAP 1079
G K P G +K P P + PPS S +P P PS PG K + P
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 1080 G 1080
G
Sbjct: 535 G 535
Score = 49.3 bits (116), Expect = 3e-05
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 15/141 (10%)
Query: 770 KPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRP 829
+PPP PPPPP PPP P PPPPP P P S ++L +K T A+ T
Sbjct: 2404 QPPPPPPPPPP----PPPPPPPPPPPPLPPPTS---PKPTILPKKKL----TVASPVTTA 2452
Query: 830 GPL--PTTQYSPGPPSGATALPPTSAAPSAQG--SPQPSASSSSQFSTSGGPWARERRAG 885
PL T + LP T +A P+PS+ S T ++ A
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP 2512
Query: 886 EEPVPGPMTPTQPPPPLSLPP 906
+ +P T TQ P + P
Sbjct: 2513 KPVIPQLPTTTQKPTDIHPKP 2533
Score = 43.9 bits (102), Expect = 0.001
Identities = 53/213 (24%), Positives = 76/213 (35%), Gaps = 30/213 (14%)
Query: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAW 485
+ PA ++ S + +PF + + PP P PPPPP P PPPPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---PPPPPPPP 2426
Query: 486 LKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP-----HREGFL---GPPASRFSVGT 537
L P IL + P A P L G P +R
Sbjct: 2427 LPPP----TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480
Query: 538 QDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDP 597
+ PP PP P++ S +H P+ P P P +P+ P+ Q P D
Sbjct: 2481 --TAPPPVPPKPSSIPSGL-VFTHRPEPSKPPIAPKP--------VIPQLPTTTQKPTDI 2529
Query: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRP 630
P L+L + + + TS ++ P P
Sbjct: 2530 HPKPTGLSLTSS--MTLNLVTSADYKLPSPTSP 2560
Score = 34.7 bits (78), Expect = 0.80
Identities = 92/414 (22%), Positives = 145/414 (35%), Gaps = 76/414 (18%)
Query: 700 KMLDESIRKEE----EQQQHEAGVAP-QPPLKE------------PFASLQSPFPTDTAP 742
K+LD EE +Q Q G +P Q P+ E P ASL S + +
Sbjct: 2057 KLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASL 2116
Query: 743 TTTAPAVAVTTTTTTTTTTTATQEEE--------KKPPPALPPPPPLAKFPPPSQPQPPP 794
T + + ++ T +T+E E ++ + + + PS+
Sbjct: 2117 TDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSV 2176
Query: 795 PPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAA 854
PP +P SL S++SV C + + ++T TT Y+ P
Sbjct: 2177 PPSDTP-SLTSSVSSV------CTTDSSSPITTLDSI--TTVYTE----------PVDMI 2217
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
+ S + S+S+ S P E + + T PP + S ++
Sbjct: 2218 TKFEDSEEISSSTYFPGSIIDYP---------EEISVSLDRTAPPDGRA-----SADHIV 2263
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAG-GVAAVSGSCK 973
+S +++E V P PV D P +AK+E G G+
Sbjct: 2264 ISLSDMASSIIESV---VPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAY 2320
Query: 974 RRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREK 1033
R +KE + E R + + ++V P + V + L S E G+EK
Sbjct: 2321 RDKKELEAE--RTKSSLSETVFDHP-------PSSVIALPMKEQLSTTYFTSGETFGQEK 2371
Query: 1034 SRPDL--GGASKAKPPTAPAP---PSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
L G S + P P P S+ SAQP PP P P PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 33.9 bits (76), Expect = 1.4
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 20/116 (17%)
Query: 832 LPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ---FSTSGGPWARERRAGEEP 888
L TT ++ G G P S PS GSP S+ + F +S + + P
Sbjct: 2356 LSTTYFTSGETFGQEK--PASQLPS--GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP 2411
Query: 889 VPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEP 944
P P P PPPP LPP S + + + A PV TA P
Sbjct: 2412 PPPPPPPPPPPPPPPLPPPTSPKPTI-------------LPKKKLTVASPVTTATP 2454
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 111 bits (278), Expect = 5e-24
Identities = 261/1167 (22%), Positives = 394/1167 (33%), Gaps = 236/1167 (20%)
Query: 228 KRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPP---PLP------GLATSPPFQLTK 278
K+++ EQ G P G+ PP PP P P P PL +++ P ++
Sbjct: 191 KKQKVVQKEQ-GKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
Query: 279 --PGLWSTLHGDAWGPE---------RKGSAPPERQEQ-------RHSLPHPYPYPAPAY 320
PG + G P+ R S P +Q + SLP P P
Sbjct: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 321 TAHPPGHRLVPAAPPG-----PGPRPPGAESHGCL-PATRPPGSDLRESRVQRSRMDSSV 374
T P PA PG PGP P A+ G P + PG+ + V
Sbjct: 310 TPGKP-----PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT-----------VKPPV 353
Query: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSH 434
P TT P P P P T S SS G + + PG+ G Q P
Sbjct: 354 QPPGTTK-PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP 411
Query: 435 HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP---PAWLKGPAC 491
++G +++P L +PA P GP+ P ++ P P PA GP
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAP------GPTKTP-------VQQPGPGKIPAQQAGPGK 458
Query: 492 RAAREDGEILEELFFGTEGP---PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
+A++ G T+ P P PA PP P + G PP + S PP+
Sbjct: 459 TSAQQTGP--------TKPPSQLPGPAKPP-PQQPGPAKPPPQQ-----PGSAKPPSQQP 504
Query: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
+T G SP P S PP S P + PSPA+ P
Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK--------------PS 550
Query: 609 APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGP 668
A S+ + +GS +P P P V P P P+ + P
Sbjct: 551 AQQSTKPVSQTGS-GKPLQP---------PTVSPSAKQPPSQGLPKTICPLCNT------ 594
Query: 669 RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
T L E A F + + + G P P L E
Sbjct: 595 -------TELLLHVPEKANFNTCTECQTTVCSL---------------CGFNPNPHLTEV 632
Query: 729 F------ASLQSPFPTDTAPTTTAPAVAVTT---TTTTTTTTTATQEEEKKPPPALPPPP 779
++ D AP ++P + T TTT+ + ++ Q ++ P P
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
Query: 780 PLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP 839
L+K P +P+ PPP P G+ +A + +P P + P
Sbjct: 693 DLSKAP---EPKKPPPLVKQPT----------------LHGSPSAKAKQP-PEADSLSKP 732
Query: 840 GPPSGATALPPTSAAPSAQGSP-QPS--------ASSSSQFSTSGGPWARERRAGEEPVP 890
PP + AP A P QP SSSS + P ++ + EE
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 891 GPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTE 950
P+ P S PP + + + + R A+D ++S +
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDS---------KAIPRPASDSKIISHPGPSSESKGQ 843
Query: 951 RLLPPAQAKEEAGGVAAVSGSCKRRQKEHQK-EHRRHRRACKDSVGRRPREGR---AKAK 1006
+ + P Q KEE K + K K + + + G RP G+ +
Sbjct: 844 KQVDPVQKKEEPK---------KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
Query: 1007 AKVPKEKSRRVLGNLDLQSEEIQGREKSRPD------LGGASKAKPPTAPAPPSAPAPSA 1060
+ P+E+SRR NL I KS+P G + + +
Sbjct: 895 SPKPQEQSRRFSLNLG----SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG 950
Query: 1061 QPTPPSASVPGKKARE-EAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFI 1119
QP P S S PG ++ AP P S+ +S + PP K +K E+ +
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPP---KSTGQAPPAPAKSIPVKKET---KAPA 1004
Query: 1120 ASEVEERRLRMADLTISHCAADVVRASRNAKVKGKFRESYLSPAQSVKPKINTE-EKLPR 1178
A ++E + + A V+ + K ++S A+ K + T+ EK P
Sbjct: 1005 AEKLEPKAEQ----------APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP- 1053
Query: 1179 EKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRL----NLGLFSTKTL 1234
K P E + P CT+ +N + + G + L + +T
Sbjct: 1054 -KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQ 1112
Query: 1235 VEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQE 1294
SG+ ++R PS + P ESS T + + QE E
Sbjct: 1113 RAISGQ-LGDIRKMPPAPSGPK----ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTE 1167
Query: 1295 EKESEDEESEEPDSTTGTPPSSAPDPK 1321
++ E+ +E S PP D K
Sbjct: 1168 AEKVILEKVKETLSMEKIPPMVTTDQK 1194
Score = 109 bits (273), Expect = 2e-23
Identities = 259/1189 (21%), Positives = 406/1189 (34%), Gaps = 195/1189 (16%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPP 254
P + ++PP+ QP P + G E PG + ++ +GL L P + PP
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP---PAQPSGLTKPLAQQPGTVKPP 352
Query: 255 PPPPPPPPPPLPGLA-TSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY 313
PP PP L PP Q T GS P ++
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQT------------------GSEKPSSEQ--------- 385
Query: 314 PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSS 373
P P A PPG PA PGP +PP + P + PG S
Sbjct: 386 --PGPKALAQPPGVGKTPAQQPGPA-KPPTQQVGTPKPLAQQPGL-------------QS 429
Query: 374 VSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS 433
+ A P P +P +S+ TG +P +PG P +
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG--PTKPPSQLPGP---AKPPPQQP 484
Query: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP-------PPPAWL 486
+ P S KP P +T PGP+ P P P +PP P A
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ-PGSTKPPSQQPGSAKPSAQQ 543
Query: 487 KGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546
PA +A++ + + + G +P PP + P A + PP+
Sbjct: 544 PSPAKPSAQQSTKPVSQ-----TGSGKPLQPPT------VSPSAKQ----------PPSQ 582
Query: 547 PTPTT---------------SSSNSNSGSH-SSSPAGPVSFPPPPYLARSIDPLPRPPSP 590
P T +N N+ + ++ F P P+L + L
Sbjct: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL------ 636
Query: 591 AQNPQDPPLVPLTLALPPAPPSSCHQN---TSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647
N Q + LA P+ P + T+ S SP+P+ + PK P
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKK----DAAPKQ 692
Query: 648 PLSKAPQP--VPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDES 705
LSKAP+P PP V + G P D +PA K + S
Sbjct: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-------------EPS 739
Query: 706 IRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
+ E+++ QP + +P L S T P + V + TT +
Sbjct: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV---QSQAEEKTTPPLK 796
Query: 766 EEEKKPPPALPPP-PPLAKFPPPSQPQPPPPPP----PSPASLLKSLASVLEGQKYCY-R 819
+ KP + PP ++ F + P+P P P+S K V QK +
Sbjct: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
Query: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWA 879
+S +P P + SP PP T P+ Q SP+P S +FS + G
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT--VPTPQQSPKPQ-EQSRRFSLNLGSIT 913
Query: 880 RERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPV 939
++ PT P ++ + + + S T + S + P P+
Sbjct: 914 DAPKS---------QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPM 964
Query: 940 DTA-----EPADSGTER---LLPPAQA-----KEEAGGVAAVSGSCKRRQKEHQKEHRRH 986
A P G + PPA A K+E AA K Q K
Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024
Query: 987 RR--ACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKA 1044
++ KDS +A K+ EKS + L E+ K P+ ++
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKL--EKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
Query: 1045 KPPTAPAPPSAPAPSAQ----------PTPPSASVPGKKAREEAPGPPGVSRADM-LKLR 1093
K P P T + S R+ P P G + M +
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
Query: 1094 SLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKG 1153
S S+ +++L+K +E + +E E+ L T+S + + + +
Sbjct: 1143 SSSQKTAVPPQVKLVK----KQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198
Query: 1154 KFRESYLSPAQSVKPKINTEEKLPRE-KLNPPTPSIYLESKRDAFSPVLLQFCTDPRNP- 1211
K + S Q KP LP E KL P I E K+ P+L + P +
Sbjct: 1199 KLEKDKASALQEKKP-------LPEEKKLIPEEEKIRSEEKK----PLLEEKKPTPEDKK 1247
Query: 1212 -ITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRT--QVQQPSDENWDL-TGTRQIWP 1267
+ + A + + L S + E E V +T + +QP + L +GT Q P
Sbjct: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
Query: 1268 CESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSS 1316
E ++ TI + Q ++ + ++ KE ++E ++ D+++ P S
Sbjct: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Score = 62.4 bits (150), Expect = 4e-09
Identities = 70/223 (31%), Positives = 84/223 (37%), Gaps = 27/223 (12%)
Query: 217 PSGEEGLS--PGGKRR--RGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSP 272
PSG +S P R R + + + PP P PPPP PPPPPPPPPPPPPLP +
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPP--PPPPPPPPPPPPPPPPPPPPLPPPTSPK 2434
Query: 273 PFQLTKPGLWSTLHGDAWGPERKGSAPPERQE--QRHSLP-------HPYPYPAPAYTAH 323
P L K L P E + + LP P P P P ++
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVP-PKPSSI 2493
Query: 324 PPG----HRLVPAAPP-GPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAA 378
P G HR P+ PP P P P LP T +D+ S S
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQ------LPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 379 TTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPG 421
T+A P P + SS S S T V P PG
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG 2590
Score = 54.7 bits (130), Expect = 7e-07
Identities = 79/337 (23%), Positives = 113/337 (33%), Gaps = 29/337 (8%)
Query: 529 PASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP 588
PAS+ G+ + P P P SS+ + + P P PPPP PLP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 589 SPAQNPQDPPLVPLTLALP-----PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG 643
SP P P LT+A P P + T+ R P R+ P V P
Sbjct: 2432 SP--KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 644 PPPGP----LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIM 699
P P + P+P P + P P P Q +P + P GL+
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPV-------IPQLPTTTQ--KPTDIHPKPTGLSLTS 2540
Query: 700 KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTT 759
M + + + +P PL P ++ SP + + T V +T + T
Sbjct: 2541 SMTLNLVTSADYKLP-----SPTSPL-SPHSNKSSP---RFSKSLTETYVVITLPSEPGT 2591
Query: 760 TTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYR 819
T ++ + P P L P PP P S ++ Q +
Sbjct: 2592 PTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT 2651
Query: 820 GTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856
A S + P TQ+ S S APS
Sbjct: 2652 PVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPS 2688
Score = 53.1 bits (126), Expect = 2e-06
Identities = 92/361 (25%), Positives = 129/361 (35%), Gaps = 51/361 (14%)
Query: 757 TTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQP--QPPPPPPPSPASLLKSLASVL-EG 813
TT Q+E+ KP + PPL + PP P Q P P KS++S E
Sbjct: 189 TTKKQKVVQKEQGKPEGII--KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
Query: 814 QKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQG-SPQPSASSSS--- 869
K GTG + P P T ++ P + P T A +G S +PS S S
Sbjct: 247 IKSQPPGTGKPIQ-GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Query: 870 -QFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERV 928
Q T G P A ++ E+ PGP P P L+ P A+ V + T
Sbjct: 306 IQQPTPGKPPA-QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT----- 359
Query: 929 GRSATDPADPVDTAEPADSGTERLLP-------------------PAQAKEEAGGVAAVS 969
PA P+ A+P T P PAQ A
Sbjct: 360 ----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 970 GSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQ 1029
G+ K ++ + + ++P G+ A+ P + S + G S ++
Sbjct: 416 GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS-QLP 474
Query: 1030 GREKSRPDLGGASKAKP--PTAPAPPSAPAPSAQPTP-------PSASVPGK-KAREEAP 1079
G K P G +K P P + PPS S +P P PS PG K + P
Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Query: 1080 G 1080
G
Sbjct: 535 G 535
Score = 49.3 bits (116), Expect = 3e-05
Identities = 44/141 (31%), Positives = 58/141 (41%), Gaps = 15/141 (10%)
Query: 770 KPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRP 829
+PPP PPPPP PPP P PPPPP P P S ++L +K T A+ T
Sbjct: 2404 QPPPPPPPPPP----PPPPPPPPPPPPLPPPTS---PKPTILPKKKL----TVASPVTTA 2452
Query: 830 GPL--PTTQYSPGPPSGATALPPTSAAPSAQG--SPQPSASSSSQFSTSGGPWARERRAG 885
PL T + LP T +A P+PS+ S T ++ A
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP 2512
Query: 886 EEPVPGPMTPTQPPPPLSLPP 906
+ +P T TQ P + P
Sbjct: 2513 KPVIPQLPTTTQKPTDIHPKP 2533
Score = 43.9 bits (102), Expect = 0.001
Identities = 53/213 (24%), Positives = 76/213 (35%), Gaps = 30/213 (14%)
Query: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAW 485
+ PA ++ S + +PF + + PP P PPPPP P PPPPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---PPPPPPPP 2426
Query: 486 LKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP-----HREGFL---GPPASRFSVGT 537
L P IL + P A P L G P +R
Sbjct: 2427 LPPP----TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-- 2480
Query: 538 QDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDP 597
+ PP PP P++ S +H P+ P P P +P+ P+ Q P D
Sbjct: 2481 --TAPPPVPPKPSSIPSGL-VFTHRPEPSKPPIAPKP--------VIPQLPTTTQKPTDI 2529
Query: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRP 630
P L+L + + + TS ++ P P
Sbjct: 2530 HPKPTGLSLTSS--MTLNLVTSADYKLPSPTSP 2560
Score = 34.7 bits (78), Expect = 0.80
Identities = 92/414 (22%), Positives = 145/414 (35%), Gaps = 76/414 (18%)
Query: 700 KMLDESIRKEE----EQQQHEAGVAP-QPPLKE------------PFASLQSPFPTDTAP 742
K+LD EE +Q Q G +P Q P+ E P ASL S + +
Sbjct: 2057 KLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASL 2116
Query: 743 TTTAPAVAVTTTTTTTTTTTATQEEE--------KKPPPALPPPPPLAKFPPPSQPQPPP 794
T + + ++ T +T+E E ++ + + + PS+
Sbjct: 2117 TDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSV 2176
Query: 795 PPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAA 854
PP +P SL S++SV C + + ++T TT Y+ P
Sbjct: 2177 PPSDTP-SLTSSVSSV------CTTDSSSPITTLDSI--TTVYTE----------PVDMI 2217
Query: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVL 914
+ S + S+S+ S P E + + T PP + S ++
Sbjct: 2218 TKFEDSEEISSSTYFPGSIIDYP---------EEISVSLDRTAPPDGRA-----SADHIV 2263
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAG-GVAAVSGSCK 973
+S +++E V P PV D P +AK+E G G+
Sbjct: 2264 ISLSDMASSIIESV---VPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAY 2320
Query: 974 RRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREK 1033
R +KE + E R + + ++V P + V + L S E G+EK
Sbjct: 2321 RDKKELEAE--RTKSSLSETVFDHP-------PSSVIALPMKEQLSTTYFTSGETFGQEK 2371
Query: 1034 SRPDL--GGASKAKPPTAPAP---PSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
L G S + P P P S+ SAQP PP P P PP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
Score = 33.9 bits (76), Expect = 1.4
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 20/116 (17%)
Query: 832 LPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ---FSTSGGPWARERRAGEEP 888
L TT ++ G G P S PS GSP S+ + F +S + + P
Sbjct: 2356 LSTTYFTSGETFGQEK--PASQLPS--GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP 2411
Query: 889 VPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEP 944
P P P PPPP LPP S + + + A PV TA P
Sbjct: 2412 PPPPPPPPPPPPPPPLPPPTSPKPTI-------------LPKKKLTVASPVTTATP 2454
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 110 bits (276), Expect = 9e-24
Identities = 211/817 (25%), Positives = 272/817 (33%), Gaps = 127/817 (15%)
Query: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP 247
Y A +G P +P P + P G+ G+ + N E LPP
Sbjct: 389 YVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP---E 445
Query: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPER----- 302
PL PPP P PPP + PP +L L LH E S PPE
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
Query: 303 ----------QEQRHSLPHPYPYPAPAY-TAHPPGHRLVPAAPP-GPGPRPPGAESHGCL 350
+E S P P P+PA T P P +PP P P E L
Sbjct: 506 PPESSPFSPLEESPLSPPEESP-PSPALETPLSPPPEASPLSPPFEESPLSPPPEE---L 561
Query: 351 PATRPPGSDLRESRVQRSRMD-------SSVSPAATTACVPY--APSRPPGLPGTTTSSS 401
P + PP + + S M S P A+ P+ +P PP P + S
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP--PEESPLSP 619
Query: 402 SSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSL 461
+S + P + +P EVS RL P SR L P LS
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVS---RLSPLPVVSR---LSPPPEESPLSP 673
Query: 462 PPGPSSPPPPPCPRLLRPPPPPAWLKGP-------------ACRAAREDGEIL-----EE 503
PP S PPP L PPP + P E+ +L +
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Query: 504 LFFGTEGP---PRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGS 560
L +EGP PRP P L R P S ++ H P P P +
Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPR-----PEEPHLSPQAEEPHLSPQPEEPCLCAVPEE--P 786
Query: 561 HSSSPA-GPVSFPPPPYLARS-------IDPLPRPPSPAQNPQDPPLVPLT--LALPPAP 610
H S A GP P P L S + P+P P + P++ L P + L P P
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 611 PSSCHQNTSGSFRRPE-SPRPRVSFPKTP-EVGPGPPPGPLSKAPQPVPPGVGELPARGP 668
S + S +P SPRP K P E G P P L P P P + L P
Sbjct: 847 EES---HLSPELEKPPLSPRPE----KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE-P 898
Query: 669 RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
L + PL P E + P G ++ L A PP P
Sbjct: 899 ALSEPGEPPLSPL---PEELPLSPSGEPSLSPQLMPP--DPLPPPLSPIITAAAPPALSP 953
Query: 729 FASLQSPFPT--DTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP------- 779
L+ PF D+ P + A + T + T + E PP LPP P
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT-DPEPVPPMILPPSPGSPVGPA 1012
Query: 780 -PLAKFPPPSQ----------PQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTR 828
P+ P P Q PQ PP SP +L S+ S L + G +
Sbjct: 1013 SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP---IGKVVGVSDEAE 1069
Query: 829 PGPLPTTQYSPGPPSGATALPPTSAAPSAQG-------SPQPSASSSSQFSTSGGPWARE 881
+ T + S P A TS PS G SP P+ S P
Sbjct: 1070 LHEMETEKVSE-PECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGI 1128
Query: 882 RRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEIS 918
G +P PG TP L P + E L ++
Sbjct: 1129 DAPGSQPEPG-QTPGSLASELKGSPVLLDPEELAPVT 1164
Score = 93.6 bits (231), Expect = 1e-18
Identities = 175/695 (25%), Positives = 226/695 (32%), Gaps = 142/695 (20%)
Query: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGC----NSEQTGLPPGLPLPPPP 250
P R + PP P+ P P E +SP + R S + P PL PPP
Sbjct: 567 PEASRLSPPPEESPMSP-----PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 251 ----LPPPPPPPPPPPPPLPGLATSPP-----------FQLTKPGLWSTLHGDAWGPERK 295
L PPP P PPP + PP +L+ P S L PE
Sbjct: 622 EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP---PEES 678
Query: 296 GSAPPERQEQRHSLPHPYPYPAPAYT--AHPPGHRLVPAAPPGPGPRPPGAESHGCLPAT 353
++PP + P P P A PP + + P P P E P +
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 354 RPPGSDLR-----------ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSS 402
P R E + + +SP C+ P P P S
Sbjct: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLS 798
Query: 403 SSSSNTGL--RGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS 460
L + EP+ + +P E SH L P S +P L HLS
Sbjct: 799 PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH---LSPQ---SEEPCLSPRPEESHLS 852
Query: 461 LPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP 520
P PP PR +PP P P EEL P PP P
Sbjct: 853 ----PELEKPPLSPRPEKPPEEPGQCPAP------------EEL-------PLFPPPGEP 889
Query: 521 HREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPA--GPVSFPPP--PY 576
LG PA + PP P P S SG S SP P PPP P
Sbjct: 890 SLSPLLGEPA------LSEPGEPPLSPLPEELPL-SPSGEPSLSPQLMPPDPLPPPLSPI 942
Query: 577 LARSIDPLPRP------PSPAQNPQDP--PLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
+ + P P P A+ DP PL L P +PP + PE
Sbjct: 943 ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTD------PEPV 996
Query: 629 RPRVSFPKTPEVGPGPPPGPLSKA-PQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAE 687
P + P PG P GP S +P+PP L + PP+ Q PA
Sbjct: 997 PPMILPPS-----PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS----QCSPPAL 1047
Query: 688 FKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT-DTAPTTTA 746
+P L+ I K++ S E + + E P+ P EP A+ P P D + +
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 747 PAVAVT--------TTTTTTTTTTATQEE----------EKKPPPALPPPPPLAKFPP-- 786
PA A+ T +Q E E K P L P LA P
Sbjct: 1108 PAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPME 1167
Query: 787 ---------------PSQPQPPPPPPPSPASLLKS 806
Q +P P P+P +L+KS
Sbjct: 1168 VYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202
Score = 79.7 bits (195), Expect = 2e-14
Identities = 200/830 (24%), Positives = 276/830 (33%), Gaps = 167/830 (20%)
Query: 180 LHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQT- 238
LHL GA G PP A + P PA LS S + L P G +S
Sbjct: 2102 LHLRIPPQPGAL-GSPPPAAAPTIFIGSPTTPAGLS-TSADGFLKPPAGSVPGPDSPGEL 2159
Query: 239 --GLPPGLPLPPP-----------PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTL 285
LPP +P P PL P P PP PP P T P Q P L ++
Sbjct: 2160 FLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPS-PTGAPAQ--PPMLGASS 2216
Query: 286 HGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAE 345
A P + PP + S P P+ P P L PG G G +
Sbjct: 2217 RPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC-----PSLDNLAVPESPGVG----GGK 2267
Query: 346 SHGCLPATRPPGSDLRESRVQRSRMDSSV------------SPAATTACVPYAPSRPPGL 393
+ L + P G + V++ + +S SP++ T P
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF 2327
Query: 394 PGTTTSSSSS---SSSNTGLRGVEPNPGI--------------PGA--DHYQTPALEVSH 434
T +S S GLR EP P PG+ D Y P L
Sbjct: 2328 KAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP 2387
Query: 435 HG-----------RLGPSAHSSRKPFLGAPAATPHLSLPPGPSSP----PPPPCPRLLRP 479
R PS SR P ++ L P P S P P PR P
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447
Query: 480 PPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFL--------GPPAS 531
P + + P+ +R+ F PPRP PP + + G L G PA+
Sbjct: 2448 DP---YSRPPSRPQSRDP-------FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497
Query: 532 RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPA 591
+ + H P + +G+ +P+ P+ F P + +P +PP P
Sbjct: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPS-PMRFTFPQAVG---EPSLKPPVP- 2552
Query: 592 QNPQDPPLVPLTLALPPAPPSSCHQNT-----------SGSFRRPESPRPRVSFPKTPEV 640
P PP + P P Q+T SGS P S S+ +P
Sbjct: 2553 -QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLR 2611
Query: 641 GPG--PPPGPLSKAP-------------QPVP----PGVG--------ELPA-RGPRLFD 672
P PPP P P PV PG G ELP + P +
Sbjct: 2612 PPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSG 2671
Query: 673 FPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL 732
T LE Q + ++L I + + + ++E++ A A PP
Sbjct: 2672 LSQTELEKQRQRQRLRELL------IRQQIQRNTLRQEKETAAAAAGAVGPP-------- 2717
Query: 733 QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQ- 791
++PA + T T + PP+ P L PS +
Sbjct: 2718 -----GSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRL 2772
Query: 792 PPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP--GPPSGATALP 849
PPPP +P+S+ + ++ G + Y+ + PG LP Q ATA
Sbjct: 2773 SRPPPPATPSSMDVNSRQLVGGSQAFYQR-----APYPGSLPLQQQQQQLWQQQQATAAT 2827
Query: 850 PTSAAPSAQ--GSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQ 897
A SA+ +P P + S G R G EPVPGP P Q
Sbjct: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG-EPVPGPAGPAQ 2876
Score = 73.9 bits (180), Expect = 1e-12
Identities = 237/1064 (22%), Positives = 349/1064 (32%), Gaps = 248/1064 (23%)
Query: 210 PPAALSGPSGEEGLSPGGKRRRG---CNSEQTGLPPGLPLPPPP-----LPPPPPPPPPP 261
P A G S + L K G + E GL P P P P P P
Sbjct: 1804 PKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKP 1863
Query: 262 PPPLPGLATSPPFQLTKPGL-------WSTLHGDAWGPERK---GSAPPERQEQRHSLPH 311
P G+ +S +++ L L D G ER+ G P + R L
Sbjct: 1864 GTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPLQR 1923
Query: 312 PY-----------------PYPAPAYTAHPPGHRLVPAAPPGPG-PRPPGAESHGCLPAT 353
P+ YP + P PG P P S G P+T
Sbjct: 1924 PFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPST 1983
Query: 354 --------RPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSS--- 402
G + +QR D + +T + V YA P L SS
Sbjct: 1984 PTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCK 2043
Query: 403 ----------SSSSNTGLRGVEPNPGIPGADHYQTPA-LEVSHHGRLGPSAHSSRKPFLG 451
++ L+ + N + Q A +++ ++G A + +P L
Sbjct: 2044 QIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPAL- 2102
Query: 452 APAATPHLSLPPGPS---SPPPPPCPRL-LRPPPPPA--------WLKGPACRAARED-- 497
HL +PP P SPPP P + + P PA +LK PA D
Sbjct: 2103 ------HLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSP 2156
Query: 498 GEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPT-PPTPTTS---- 552
GE+ +L P P +P ++ F PA + + + PPT PP P+ +
Sbjct: 2157 GELFLKL-------PPQVPAQVPSQDPFGLAPA--YPLEPRFPTAPPTYPPYPSPTGAPA 2207
Query: 553 -------SSNSNSGS----HSSSPAGPVSFP--PPPYL---ARSIDPLPRPPSP------ 590
SS +G H++ P P P P P+L S+D L P SP
Sbjct: 2208 QPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK 2267
Query: 591 AQNP-----------------------QDPPLVPLTLALPPAPPSSCHQN-----TSGSF 622
A P P P L +P S H T F
Sbjct: 2268 ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF 2327
Query: 623 RRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQF 682
+ P +PR P++P +G P P ++A P PP ++ F P D +
Sbjct: 2328 KAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI---------FRPGSYTDPY 2378
Query: 683 EEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF----ASLQSPFPT 738
+P + P R + + + P+ +PF AS QS +
Sbjct: 2379 AQP---PLTP--------------RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQ-SS 2420
Query: 739 DTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPP-- 796
+P T P A + T + + +PP P A P +PQPP
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFK 2480
Query: 797 ------------------PPSPASLLKSLASVLEGQKYCY---RGTGAAVSTRPGPLPTT 835
P PA L A V GQ + GTGA V T P P+ T
Sbjct: 2481 AGSLAHTSLGAGGFPAALPAGPAGELH--AKVPSGQPPNFVRSPGTGAFVGT-PSPMRFT 2537
Query: 836 ------QYSPGPPSGATALPPTSAAPS------AQGSPQPS--ASSSSQFSTSGGPWARE 881
+ S PP LPP S G PQ + ++ F SG P
Sbjct: 2538 FPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPS 2597
Query: 882 RRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDT 941
+G ++P +PP L PPA S L +S +R G ++ PV+
Sbjct: 2598 --SGSTGESYGLSPLRPPSVLP-PPAPDGS--LPYLSHGAS---QRSGITS-----PVEK 2644
Query: 942 AEPADSGTERLLPPAQAK-EEAGGVAAVSGSCKRRQKEHQK-EHRRHRRACKDSVGRRPR 999
E +G L A+ + G++ +S + +Q++ Q+ R+ + + R+ +
Sbjct: 2645 REDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK 2704
Query: 1000 EGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPS 1059
E A A V S G E S P S+ + P A +
Sbjct: 2705 ETAAAAAGAVGPPGS--------------WGAEPSSPAFEQLSRGQTPFAGTQDKSSLVG 2750
Query: 1060 AQPTPPSASVPGKKA-----REEAPGPPGVSRADMLKLRSLSEG 1098
P+ S + G + R P PP + + R L G
Sbjct: 2751 LPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGG 2794
Score = 65.5 bits (158), Expect = 4e-10
Identities = 92/356 (25%), Positives = 131/356 (36%), Gaps = 64/356 (17%)
Query: 587 PPSPAQNPQDPPLV------------PLTLALPPAP-PSSCHQNTSGSFRRPESPRPRVS 633
PP P P D P +T P P P C G + P++
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG--KAGVQLEPQLE 431
Query: 634 FPKTPEVGPGPPP--GPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKIL 691
P E+ PPP PLS P+ P P RL PP L PA L
Sbjct: 432 APLNEEMPLLPPPEESPLSPPPEESPTSP---PPEASRLSP-PPEEL------PAS--PL 479
Query: 692 PDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQ-SPF-PTDTAPTTTAPAV 749
P+ L ++ + L+ES + E+ ++P PP PF+ L+ SP P + +P + A
Sbjct: 480 PEAL-HLSRPLEESPLSPPPE---ESPLSP-PPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 750 AVTTTTTTTTTTTATQEEEKKPPPA-LP--PPPPLAKFPPPSQPQP-PPPPPPSPASLLK 805
++ + + +E PPP LP PPP ++ PP + P PPP SP S
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 806 SLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA--APSAQGSPQP 863
+ + P + SP P + PP ++ +P + SP
Sbjct: 595 EASRLFP------------------PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISR 919
S S P R PV ++P PLS PP S + E SR
Sbjct: 637 PPPEESPMS----PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Score = 56.2 bits (134), Expect = 3e-07
Identities = 179/779 (22%), Positives = 252/779 (32%), Gaps = 133/779 (17%)
Query: 211 PAAL-SGPSGE-EGLSPGGKRRRGCNSEQTGLPPGLPLP----------PPPLPPPPPPP 258
PAAL +GP+GE P G+ S TG G P P P L PP P P
Sbjct: 2495 PAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP 2554
Query: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAP--PERQEQRHS-------- 308
PPP P L KP ST + A G +P P S
Sbjct: 2555 GLPPPHGINSHFGPGPTLGKPQ--STNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
Query: 309 ---LPHPYPYPAPAYTAHPPGHRLVPAAP------PGPGPRPPGAESHGCLPATRPPG-S 358
LP P P + Y +H R +P PG G A + LP T+ PG S
Sbjct: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAE--LPGTQDPGMS 2670
Query: 359 DLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPG 418
L ++ +++ R + + R T ++++ + G G EP+
Sbjct: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK---ETAAAAAGAVGPPGSWGAEPS-- 2725
Query: 419 IPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPP------PP 472
+PA E G+ PF G + + LPP S P P
Sbjct: 2726 --------SPAFEQLSRGQT---------PFAGTQDKSSLVGLPPSKLSGPILGPGSFPS 2768
Query: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASR 532
RL RPPPP P+ +L G++ + AP P G L +
Sbjct: 2769 DDRLSRPPPPAT----PSSMDVNS-----RQLVGGSQAFYQRAPYP-----GSLPLQQQQ 2814
Query: 533 FSVGTQDSHTPPTPPT-------PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLP 585
+ Q T T P+T + S AG + P P +P+P
Sbjct: 2815 QQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG-----EPVP 2869
Query: 586 RPPSPAQ------NPQD---PPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPK 636
P PAQ N Q P P PP P + PE R
Sbjct: 2870 GPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGL 2929
Query: 637 TPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI--LPDG 694
P+ PP L+ + P P G G L + PP+ E P + LP
Sbjct: 2930 PPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCE 2989
Query: 695 LANIMKMLDESIRKEEEQQQHEAGVAPQPPL-KEPFASLQS-----PFPTDTAPTTTAPA 748
+ D E++++ G+ + +L++ P D
Sbjct: 2990 DPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDL 3049
Query: 749 VAVTTTTTTT------------TTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPP 796
+A T T +A ++ E++ P PL P P
Sbjct: 3050 LAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVEPGPLG---------PEERP 3100
Query: 797 PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856
PP+ + LASVL K G S + T + P P + + L S
Sbjct: 3101 PPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGL-GLKPGQS 3159
Query: 857 AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLE 915
GS + + + FS+SG +A GP P PLS P S E E
Sbjct: 3160 MMGS-RDTRMGTGPFSSSG---HTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFE 3214
Score = 55.1 bits (131), Expect = 6e-07
Identities = 160/707 (22%), Positives = 231/707 (32%), Gaps = 153/707 (21%)
Query: 510 GPPRPAPPPLPH--REGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAG 567
GP PA P L H G LGP + G + + P + T +++ G +
Sbjct: 3998 GPGMPAKP-LQHFSSPGALGP--TLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054
Query: 568 PVSFPPPPYLARS----------IDPLPRPPSPAQNPQDPPL------------------ 599
P S P + + P P+P P+ PPL
Sbjct: 4055 PESMATEPGEVKPSLSGDSQLLLVQPQPQP-QPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
Query: 600 ----------------VPLTLALPPAP----PSSCHQNTSGSFRRPESPRPRVSFPKTPE 639
VP LA P P S QN G +P + P
Sbjct: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGP------QQPMLERPMQNN 4167
Query: 640 VGPGPP-PGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANI 698
GP PP PGP+ ++ Q +P GVG +P G ++ P + P +
Sbjct: 4168 TGPQPPKPGPVLQSGQGLP-GVGIMPTVGQLRAQLQGVLAKN----PQLRHLSPQQQQQL 4222
Query: 699 MKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTT 758
+L + Q Q V PP +EP T T+P
Sbjct: 4223 QALL------MQRQLQQSQAVRQTPPYQEP--------GTQTSPLQGLLGCQPQLGGFPG 4268
Query: 759 TTTTATQEEEKKP----PPALPPPP----------PLAKFPPPSQPQPPPPPP--PSPAS 802
T QE P PP LP PP P+ PPPS PQ P P PSP+S
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 803 LLKSLASVLEGQKYCYRGTGAAVSTRPG-------PLPTTQYSPG-----PPSGA--TAL 848
L + A + + G + PG L T +S G PP T
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQK 4388
Query: 849 PPTSAA-----PSAQGSPQPSASSSS------QFSTSGGPWARERRAGEEPVPGPMTPTQ 897
P S+ G P AS S + + G + +R A EP+ P T
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNH 4448
Query: 898 PPPPLSLPPARSESE--VLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPP 955
L L RSE+ +L+++ RA + S A+ + +G E+ L
Sbjct: 4449 ----LLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQG 4504
Query: 956 AQA-KEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREG---RAKAKAKVPK 1011
+ KE+A ++ KR QK + ++ K+ G R E + K + +
Sbjct: 4505 TPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKED-GVRASEALLKQLKQELSLLP 4563
Query: 1012 EKSRRVLGNLDLQSE-----EIQGREKSRPDLGGASKAKPP-------------TAPAPP 1053
+ N L + + G+ + R G + P P PP
Sbjct: 4564 LTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPP 4623
Query: 1054 SAPAPSAQPTPPSASVPGKKAREEA---PGPPGVSRADMLKLRSLSE 1097
S+ P+ P+ V G EE P +R LR SE
Sbjct: 4624 SSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSE 4670
Score = 46.6 bits (109), Expect = 2e-04
Identities = 83/330 (25%), Positives = 113/330 (34%), Gaps = 73/330 (22%)
Query: 171 PPL------EQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLS 224
PPL +Q +LLH ++G G + ++ P + L+ PS G
Sbjct: 4093 PPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHL--------LAQPSVSLGDQ 4144
Query: 225 PGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWST 284
PG + +Q L + P PP P P LPG+ P + L
Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV 4204
Query: 285 LHGDAWGPERKGSAPPERQ-----------EQRHSLPHPYPYPAPAYTAHP--------- 324
L A P+ + +P ++Q +Q ++ PY P P
Sbjct: 4205 L---AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP 4261
Query: 325 -----PGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAAT 379
PG + P G GPRP G LPA PPG+ + + V P
Sbjct: 4262 QLGGFPGPQTGPLQELGAGPRPQGPPR---LPA--PPGA------LSTGPVLGPVHPTPP 4310
Query: 380 TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLG 439
+ P P RP LP S SS + L P PG Q P LE GR+
Sbjct: 4311 PSS-PQEPKRPSQLP----SPSSQLPTEAQL-----PPTHPGTPKPQGPTLE-PPPGRVS 4359
Query: 440 PSAHSSRKPFLGAPAATPHLSLPPGPSSPP 469
P+A A A S GP PP
Sbjct: 4360 PAA---------AQLADTLFSKGLGPWDPP 4380
Score = 41.6 bits (96), Expect = 0.007
Identities = 71/275 (25%), Positives = 96/275 (34%), Gaps = 62/275 (22%)
Query: 841 PPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPV------PGPMT 894
PP + PP +P+ SP P AS S P E A P P +
Sbjct: 443 PPEESPLSPPPEESPT---SPPPEASRLS-------PPPEELPASPLPEALHLSRPLEES 492
Query: 895 PTQPPP---PLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTER 951
P PPP PLS PP S LEE P P + + P+ +
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEE-----------------SPLSPPEESPPSPALETP 535
Query: 952 LLPPAQAKEEAGGV--AAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKV 1009
L PP +A + + +S + E R ++S P E ++
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE---ESPMSP 592
Query: 1010 PKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASV 1069
P E SR L EE S PP +P S P +++ +PP
Sbjct: 593 PPEASR-----LFPPFEE--------------SPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 1070 PGKKAREEAP--GPPGVSRADMLKLRSLSEGPPKE 1102
P EE+P PP VSR L + S PP+E
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Score = 40.8 bits (94), Expect = 0.011
Identities = 99/408 (24%), Positives = 129/408 (31%), Gaps = 102/408 (25%)
Query: 182 LEHKRNYGAKRGGPPVKRAAEPPVVQP-VPPAALSGPSGEEGLSPGGKRRRGCNSEQTGL 240
L+H + GA G + E V P V A GPS +G G G E
Sbjct: 4006 LQHFSSPGAL-GPTLLLTGKEQNTVDPAVSSEATEGPSTHQG----GPLAIGTTPESMAT 4060
Query: 241 PPG------------LPLPPPPLPPPPPPPPPPPPPLPGL-------------------- 268
PG L + P P P P PP LPG
Sbjct: 4061 EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLG 4120
Query: 269 ------ATSPPFQLTKPGLWSTLHGDAWGPERKGSAPP-----ERQEQRHSLPHPYPYPA 317
A+S P L +P S GD G + P ER Q ++ P P P P
Sbjct: 4121 SGSSSEASSVPHLLAQP---SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP-PKPG 4176
Query: 318 PAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRE-SRVQRSRMDSSVSP 376
P + G L PG G P + L LR S Q+ ++ + +
Sbjct: 4177 PVLQS---GQGL-----PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQ 4228
Query: 377 AATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPN-PGIPGADHYQTPALEVSHH 435
+ P PGT TS GL G +P G PG
Sbjct: 4229 RQLQQSQAVRQTPPYQEPGTQTSPLQ------GLLGCQPQLGGFPGP------------- 4269
Query: 436 GRLGPSAHSSRKPFLGAPAATPHLSLPP---------GPSSPPPPPCPRLLRPPPPPAWL 486
+ GP P P P L PP GP P PPP + P P+ L
Sbjct: 4270 -QTGPLQELGAGP---RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP--QEPKRPSQL 4323
Query: 487 KGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS 534
P+ + E +L G P+P P L G + P A++ +
Sbjct: 4324 PSPSSQLPTE-----AQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Score = 40.8 bits (94), Expect = 0.011
Identities = 73/291 (25%), Positives = 97/291 (33%), Gaps = 61/291 (20%)
Query: 145 PRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPP 204
P +G+L+ AQL + Q R +Q+ LL + A R PP + P
Sbjct: 4192 PTVGQLR-AQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE----P 4246
Query: 205 VVQPVPPAALSGPSGEEGLSPGGK----RRRGCNSEQTGLPPGLPLPPP---------PL 251
Q P L G + G PG + + G G PP LP PP P+
Sbjct: 4247 GTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-PPRLPAPPGALSTGPVLGPV 4305
Query: 252 PPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPH 311
P PPP P P P SP QL P E Q LP
Sbjct: 4306 HPTPPPSSPQEPKRPSQLPSPSSQL----------------------PTEAQ-----LPP 4338
Query: 312 PYP-YPAP-AYTAHPPGHRLVPAA--------PPGPGPRPPGAESHGCLPATRPPGSDLR 361
+P P P T PP R+ PAA G GP P +P S L
Sbjct: 4339 THPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDP---PDNLAETQKPEQSSLV 4395
Query: 362 ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG 412
+ +++ V P A+ + P P G + ++ G G
Sbjct: 4396 PGHL--DQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPG 4444
Score = 37.7 bits (86), Expect = 0.095
Identities = 37/111 (33%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query: 544 PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPL- 602
P PPT + + N ++ A P P PP P P PSPA P + PLV L
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPP-------PSPLAPSPASPPTE-PLVELP 4937
Query: 603 --TLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSK 651
LA PP P ++ PES RP+ + PE G P L K
Sbjct: 4938 TEPLAEPPVPSPLPLASS------PESARPKPR-ARPPEEGEDSRPPRLKK 4981
Score = 35.4 bits (80), Expect = 0.47
Identities = 44/181 (24%), Positives = 65/181 (35%), Gaps = 44/181 (24%)
Query: 632 VSFPKTPEVGPGPPPGPLSKAPQPVPPGV-GELPARGP---RLFD--FPPTPLEDQFEEP 685
V FP++P P ++ P G+ G+ P GP + FD P L+ Q +
Sbjct: 4817 VLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLD-- 4874
Query: 686 AEFKILPDGLANIMKMLDESIRKEEEQQQH---------EAGVAPQPPLKEPFASLQSPF 736
I+ +L + E QH + PP +EP SP
Sbjct: 4875 ------------ILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEP-----SPP 4917
Query: 737 PTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPP 796
P+ AP+ +P T E P +P P PLA P ++P+P P
Sbjct: 4918 PSPLAPSPASPPTEPLVELPT----------EPLAEPPVPSPLPLASSPESARPKPRARP 4967
Query: 797 P 797
P
Sbjct: 4968 P 4968
Score = 34.7 bits (78), Expect = 0.80
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 237 QTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTL----HGDAWGP 292
Q PP PPP P P P PP PL L T P L +P + S L ++ P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP---LAEPPVPSPLPLASSPESARP 4961
Query: 293 ERKGSAPPERQEQR 306
+ + P E ++ R
Sbjct: 4962 KPRARPPEEGEDSR 4975
Score = 33.5 bits (75), Expect = 1.8
Identities = 30/98 (30%), Positives = 37/98 (37%), Gaps = 22/98 (22%)
Query: 197 VKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPP 256
V++ + PP +P PP + PS PP PL LP P
Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPS-------------------PASPPTEPL--VELPTEPL 4941
Query: 257 PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPER 294
PP P PLP LA+SP KP G+ P R
Sbjct: 4942 AEPPVPSPLP-LASSPESARPKPRARPPEEGEDSRPPR 4978
Score = 31.2 bits (69), Expect = 8.9
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 7/48 (14%)
Query: 762 TATQEEEKKPPP-------ALPPPPPLAKFPPPSQPQPPPPPPPSPAS 802
+A EE PPP A PP PL + P +PP P P AS
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLAS 4954
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 108 bits (270), Expect = 4e-23
Identities = 224/967 (23%), Positives = 332/967 (34%), Gaps = 213/967 (22%)
Query: 201 AEPP--VVQPVPPA-ALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPP 257
A PP V Q VP A P + L P K S +PP +P P P P P
Sbjct: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSP 1859
Query: 258 PPPPPPPLPGLATSPPFQLTKPGLWST----------------LHGDAWGPERKG--SAP 299
P PP P P T PF W T L G + P K A
Sbjct: 1860 APGPPTPAPESHTPAPFS------WGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAE 1913
Query: 300 PERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSD 359
ER+E+ + AP ++H ++ A+ P E P P
Sbjct: 1914 GEREEEGRA-------EAPDKSSH--SSKVPEASKSHATTEPEQTEPEQREPTPYPDERS 1964
Query: 360 LRESRVQRSRMDSSVSPAATTACVPY--APSRPPGLPGTTTSSSSSSSSNTGLRGVEPNP 417
+ + + M + + PA T P A PP L ++ +++ NT +P
Sbjct: 1965 FQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCL----STKEAAAGRNTSAEKELSSP 2020
Query: 418 GIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLL 477
P + TP S+ GP+ +P P+ P L+ P PP P L
Sbjct: 2021 ISPKSLQSDTPTF--SYAALAGPTVPPRPEP---GPSMEPSLTPPA-----VPPRAPILS 2070
Query: 478 RPPPPPAWLKGPACRAAR-------------EDGEILEELFFGTEGPPR-----PAPP-P 518
+ P PP +C R +D EL G P P+PP P
Sbjct: 2071 KGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHP 2130
Query: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLA 578
+P L P DSH P P+ + FP +
Sbjct: 2131 IPMGSPTLWPETEAHVSPPLDSHLGPARPS--------------------LDFPASAFGF 2170
Query: 579 RSIDPLP-RPPSPAQNPQDPPLVPLT------LALPPAPPSSCHQNTSGSFRRPESPRPR 631
S+ P P + PSPA+ P+ P L LAL P PP+ + ++P
Sbjct: 2171 SSLQPAPPQLPSPAE-PRSAPCGSLAFSGDRALALAPGPPTRTRHDEY--LEVTKAPSLD 2227
Query: 632 VSFPKTPEVGPGPPPGPL-SKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI 690
S P+ P P P PL S P+P P + E + TP+
Sbjct: 2228 SSLPQLPS--PSSPGAPLLSNLPRPASPALSEGSSSEAT------TPV------------ 2267
Query: 691 LPDGLANIMKMLDESIRK-EEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAV 749
++++ + S+ E+E + + G+ P L SP P + APA
Sbjct: 2268 ----ISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPL-SPAPPASLDLALAPAP 2322
Query: 750 AVTTTT---TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKS 806
++ ++ +KP P P A P P PP P+PA
Sbjct: 2323 SLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETS--PNPPGPAPAKAENE 2380
Query: 807 LASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQ---- 862
A+ + GA S+RP L + + P P+G + PP+SA+P + PQ
Sbjct: 2381 EAAACPAWERGAWPEGAERSSRPDTLLSPE-QPVCPAGGSGGPPSSASPEVEAGPQGCAT 2439
Query: 863 ------------------PSASSSSQFSTSG----GPWARERRAGEEPVPGPMTPTQPPP 900
P + ST G R R G GP T P
Sbjct: 2440 EPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP 2499
Query: 901 PLSLP---PARSESEVLEEISRACETLVERVGRSATDPAD--PVDTAEPADSGTERLLP- 954
P S ++S+S+V E + C ++ + + D PVD A SGT P
Sbjct: 2500 PTSASDSGSSQSDSDVPPE-TEECPSITAEAALDSDEDGDFLPVDKAGGV-SGTHHPRPG 2557
Query: 955 -----------------PAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRR 997
P + G+++ SG +R +++ + + R VGR
Sbjct: 2558 HDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGR---------VGR- 2607
Query: 998 PREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPA 1057
RA KAK P +RR+ +++G+ P G A +A + APP +
Sbjct: 2608 ----RAPGKAK-PASPARRL---------DLRGKRSPTPGKGPADRA----SRAPPRPRS 2649
Query: 1058 PSAQPTP 1064
++Q TP
Sbjct: 2650 TTSQVTP 2656
Score = 65.5 bits (158), Expect = 4e-10
Identities = 148/655 (22%), Positives = 210/655 (32%), Gaps = 116/655 (17%)
Query: 194 GPPVKRAAEPPVVQPVPPAALSGPS----------GEEGLSPGGKRRRGCNSEQTGLPPG 243
GP ++ + PP V P P GPS + SP K + + +
Sbjct: 2050 GPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSE 2109
Query: 244 LPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQ 303
L P P PP P+P + P LW PE + P
Sbjct: 2110 LEKGAREQPEKEAQSPSPPHPIP---------MGSPTLW---------PETEAHVSPPLD 2151
Query: 304 EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
+PA A+ L PA P P P P + G L + L
Sbjct: 2152 SHLGPARPSLDFPASAFGF----SSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPG 2207
Query: 364 RVQRSRMDSSVSPAATTACVPYAPSRP-PGLPGTTTSSS----SSSSSNTGLRGVEPNPG 418
R+R D + + P P P PG S+ +S + + G P
Sbjct: 2208 PPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPV 2267
Query: 419 IPGADHYQTPALEVSHH--GRLG----PSAHS--SRKPFLGAPAATPHLSLPPGPSSPPP 470
I +P+LE + G L P+AHS P AP A+ L+L P PS P
Sbjct: 2268 ISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGD 2327
Query: 471 P---------PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH 521
C P P + C AA E + PP PAP +
Sbjct: 2328 MGDGILPCHLECSEAATEKPSPFQVPSEDC-AANGPTET-------SPNPPGPAPAKAEN 2379
Query: 522 REGFLGPPASR--FSVGTQDSHTPPT---PPTPTTSSSNSNSGSHSSSP---AGP--VSF 571
E P R + G + S P T P P + S S+SP AGP +
Sbjct: 2380 EEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCAT 2439
Query: 572 PPPPYLARSIDPLPRPPSPAQ------NPQDPPLV------------------PLTLALP 607
P P+ PP P + ++ LV P+T P
Sbjct: 2440 EPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP 2499
Query: 608 PAPPSSCHQNTSGSFRRPESPR-PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
P S + S S PE+ P ++ + P+ KA G
Sbjct: 2500 PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAG-------GVSGTH 2552
Query: 667 GPRL-FDFPPTPLEDQFEEPAEFKIL---PDGLANIMKMLDESIRKEEEQQQHEAGVAP- 721
PR D PP P D P + P+GL++ + E +R++E+ Q AP
Sbjct: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRV-ERLREKEKVQGRVGRRAPG 2611
Query: 722 -----QPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
P + +SP P P A +TT+ T A +++ P
Sbjct: 2612 KAKPASPARRLDLRGKRSPTP-GKGPADRASRAPPRPRSTTSQVTPAEEKDGHSP 2665
Score = 63.2 bits (152), Expect = 2e-09
Identities = 176/777 (22%), Positives = 244/777 (31%), Gaps = 187/777 (24%)
Query: 445 SRKPF--LGAPAATPHL-----SLPPGPSSPPPPP--CPRLLRPPPPPAWLKGPACRAAR 495
+R PF + PA+ P + PG SP P P P + P P+WL +
Sbjct: 1789 TRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPK 1848
Query: 496 EDGEILEELFFGTEGPPRPAPP---PLPHREGFL-----------------GPPAS---- 531
D + GPP PAP P P G G P S
Sbjct: 1849 -DRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGK 1907
Query: 532 --RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPS 589
R + G ++ P ++ SS S S + P P +P P P
Sbjct: 1908 DYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEP-----EQREPTPYPDE 1962
Query: 590 ------------------PAQNPQDPPLVPLTLALPPAPP------SSCHQNTSGS--FR 623
PA ++PPL A PP ++ +NTS
Sbjct: 1963 RSFQYADIYEQMMLTGLGPACPTREPPLG----AAGDWPPCLSTKEAAAGRNTSAEKELS 2018
Query: 624 RPESPRPRVSFPKT--------PEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPP 675
P SP+ S T P V P P PGP S P PP V P R P L P
Sbjct: 2019 SPISPKSLQSDTPTFSYAALAGPTVPPRPEPGP-SMEPSLTPPAV---PPRAPILSKGPS 2074
Query: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
PL + + P + D+S E ++ A + P KE QSP
Sbjct: 2075 PPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKG-----AREQPEKEA----QSP 2125
Query: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPA---LPPPPPLAKFPPP----S 788
P P + T + E PP L P P FP S
Sbjct: 2126 SPPHPIPMGSP--------------TLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFS 2171
Query: 789 QPQPPPPPPPSPASLLKSLASVL--EGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGAT 846
QP PP PSPA + L G + G TR +P S
Sbjct: 2172 SLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLP 2231
Query: 847 ALPPTSA--APSAQGSPQPSASSSSQFSTSGGPW---------------ARERRAGE-EP 888
LP S+ AP P+P++ + S+ S+S A E+ +GE +P
Sbjct: 2232 QLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDP 2291
Query: 889 VPGP-------MTPTQPPPP----LSLPPARSESEVLEEISRACETLVERVGRSATDPAD 937
P +TP P PP L+L PA S + + C +AT+
Sbjct: 2292 GMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHL---ECSEAATEKPS 2348
Query: 938 P--VDTAEPADSGTERLLP----PAQAKEEAGGVAAVSGSCKRRQKEHQKEHRR------ 985
P V + + A +G P PA AK E AA + E + R
Sbjct: 2349 PFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLS 2408
Query: 986 --------------------HRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQS 1025
A PR R + + + DL +
Sbjct: 2409 PEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLST 2468
Query: 1026 EEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
EE++ L G + P P P TPP+++ ++ ++ PP
Sbjct: 2469 EEVR--------LVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPP 2517
Score = 40.4 bits (93), Expect = 0.015
Identities = 104/449 (23%), Positives = 146/449 (32%), Gaps = 98/449 (21%)
Query: 724 PLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP------ 777
P +E +SPF + P + V +A +E P P L P
Sbjct: 1781 PPEEEDKLTRSPFEIISPPASPPEMVG-------QRVPSAPGQESPIPDPKLMPHMKNEP 1833
Query: 778 --PPPLAKFPP--------PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVST 827
P LA PP P P P P PP+PA + A G Y AAV
Sbjct: 1834 TTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAE-YDSVVAAVQE 1892
Query: 828 RPGPLPTTQYSP-----GPPSGATALPPTSAAP--SAQGSPQPSASSSSQFSTSGGPWAR 880
L YSP G + AP S+ S P AS S +T
Sbjct: 1893 GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHA-TTEPEQTEP 1951
Query: 881 ERRAGEEPVP---------------------GPMTPTQPPPPLSL---PPARSESEVLEE 916
E+R EP P GP PT+ PP + PP S E
Sbjct: 1952 EQR---EPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAG 2008
Query: 917 ISRACE-------------------TLVERVGRSATDPADPVDTAEPADSGTERLLPPAQ 957
+ + E + G + +P + EP S T +PP
Sbjct: 2009 RNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEP--SLTPPAVPPRA 2066
Query: 958 AKEEAGGVAAVSG---SCK--RRQKEHQKEHRRH-RRACKDSVGRRPREGRAKAKAKVPK 1011
G ++G SC RR ++ R H + DS + + + +A+ P
Sbjct: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPS 2126
Query: 1012 EKSRRVLGNLDLQSEEIQ----------GREKSRPDLGGASKAKPPTAPAPPSAPAPSAQ 1061
+G+ L E G + D ++ PAPP P+P+
Sbjct: 2127 PPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEP 2186
Query: 1062 PTPPSASVP--GKKAREEAPGPPGVSRAD 1088
+ P S+ G +A APGPP +R D
Sbjct: 2187 RSAPCGSLAFSGDRALALAPGPPTRTRHD 2215
Score = 40.4 bits (93), Expect = 0.015
Identities = 134/577 (23%), Positives = 178/577 (30%), Gaps = 102/577 (17%)
Query: 25 AGAWSSCPPHPP-------PRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGH------P 71
A +SS P PP PRSA P G + S + AP PP+ + P
Sbjct: 2167 AFGFSSLQPAPPQLPSPAEPRSA--PCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAP 2224
Query: 72 SKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYH 131
S P P+P L S L PA P L SE S EAT
Sbjct: 2225 SLDSSLPQLPSPSSPGAPLLSN-------LPRPASPAL---------SEGSSSEATTPVI 2268
Query: 132 SAL--RYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYG 189
S++ R+ S G L + P +W+L L
Sbjct: 2269 SSVAERFSPSLEAAEQESGELDPG---------------MEPAAHSLWDLTPLS------ 2307
Query: 190 AKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPP 249
P A+ + P P +L G G+ G+ P C+ T P +P
Sbjct: 2308 ------PAPPASLDLALAPAP--SLPGDMGD-GILPCHLE---CSEAATEKPSPFQVPSE 2355
Query: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSL 309
P P PP P A + + W AW PE ER + +L
Sbjct: 2356 DCAANGPTETSPNPPGPAPAKAENEEAAACPAWER---GAW-PEGA-----ERSSRPDTL 2406
Query: 310 PHPYPYPAPAYTAHPPGHRLVPAAPPGPG-----PRPPGAE-SHGCLPATRPPGSDLRES 363
P PA + P P GP PRP E S L PP D R+
Sbjct: 2407 LSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDL 2466
Query: 364 RVQRSRMDSSVS------PAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG-VEPN 416
+ R+ P T P PP T+ S S SS S++ + E
Sbjct: 2467 STEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPP----TSASDSGSSQSDSDVPPETEEC 2522
Query: 417 PGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL 476
P I AL+ G P + P P P P PP P +
Sbjct: 2523 PSITAE-----AALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDV 2577
Query: 477 LRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVG 536
P + RE ++ + G +PA P R G + G
Sbjct: 2578 CMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASP--ARRLDLRGKRSPTPGKG 2635
Query: 537 TQD--SHTPPTPPTPTTS-SSNSNSGSHSSSPAGPVS 570
D S PP P + T+ + HS G V+
Sbjct: 2636 PADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVN 2672
Score = 34.7 bits (78), Expect = 0.80
Identities = 95/420 (22%), Positives = 139/420 (33%), Gaps = 72/420 (17%)
Query: 47 CSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPA- 105
CS + + P P +P +++G P++ +P P P P + E C PA
Sbjct: 2339 CSEAATEKPSPFQVPSEDCAANG-PTET--SPNPPGPAPAKAENEEAAAC-------PAW 2388
Query: 106 QPGLWEQLGQLYESEHD---SEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGS 162
+ G W + G S D S E C A GG + P + +A T
Sbjct: 2389 ERGAWPE-GAERSSRPDTLLSPEQPVC--PAGGSGGPPSSASPEV----EAGPQGCATEP 2441
Query: 163 CQHRAKV--------LPPLEQVWNLLHLEHKR--NYGAKRGGPPVKRAAEPPVVQPVPPA 212
HR ++ LPP +L E + G +R G P PV PP
Sbjct: 2442 RPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPT 2501
Query: 213 ALSGPSGEEGLSPGGKRRRGCNS------------------EQTGLPPGLPLP-----PP 249
+ S + S C S ++ G G P PP
Sbjct: 2502 SASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPP 2561
Query: 250 PLPPPPPPPPPPPPPL----PGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305
PLP P P P PP P + P +S ++ + + G G G A P +
Sbjct: 2562 PLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRV-GRRAPGKAKPASPAR 2620
Query: 306 RHSL-----PHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
R L P P PA + PP R + P E G P ++ + L
Sbjct: 2621 RLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQV------TPAEEKDGHSPMSKGLVNGL 2674
Query: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
+ + S SS +P + Y P+ G +S + G +P G P
Sbjct: 2675 KAGPMALSSKGSSGAPVYVD--LAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEP 2732
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 105 bits (263), Expect = 3e-22
Identities = 129/479 (26%), Positives = 153/479 (31%), Gaps = 108/479 (22%)
Query: 205 VVQPVPPAALSGPSGEEGLSP-GGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPP 263
V Q P+ ++G +G P GG + +G S PPG P PPP P PPPP
Sbjct: 23 VSQEESPSLIAG--NPQGAPPQGGNKPQGPPS-----PPGKPQGPPPQGGNQPQGPPPP- 74
Query: 264 PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAH 323
PG PP Q G GP +G ++ S P P P
Sbjct: 75 --PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG----DKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 324 PPGHRLVPAAPPGP---------GPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSV 374
P G P P GP GP PPG P PP D +SR RS
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGK------PQGPPPQGD-NKSRSSRSPPGKPQ 181
Query: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSH 434
P P P PPG P + P PG P Q P + +
Sbjct: 182 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG------PPPPGKP-----QGPPPQGDN 230
Query: 435 HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAA 494
+ S+R P P P PPP + PPPPP +GP +
Sbjct: 231 ------KSQSARSP-------------PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 495 REDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSS 554
+ +GPP P P GPP S P P P
Sbjct: 272 NK-----------PQGPPPPGKPQ--------GPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 555 NSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSC 614
N P GP PPPP P PP PQ PP PP P
Sbjct: 313 N--------QPQGP---PPPPG-----KPQGPPPQGGNKPQGPP--------PPGKPQGP 348
Query: 615 HQNTSGSFRRPESPRPRVSFPKTPE----VGPGPPPGPLSKAPQPVPPGVGELPARGPR 669
R SP + P E GP PP G + PQ P G + P R P+
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Score = 96.7 bits (239), Expect = 2e-19
Identities = 110/419 (26%), Positives = 132/419 (31%), Gaps = 83/419 (19%)
Query: 189 GAKRGGPPVKRAAEPPVVQPVPPAALSGPSGE-----EGLSPGGKRR----RGCNSEQTG 239
G +G PP + P P PP GP + +G P GK + +G S
Sbjct: 55 GKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 112
Query: 240 LPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAP 299
PPG P PPP P PPPP PG PP Q G GP +G
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD-- 167
Query: 300 PERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGP---------GPRPPGAESHGCL 350
+ S P P P P G P P GP GP PPG
Sbjct: 168 -NKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK------ 220
Query: 351 PATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGL 410
P PP D +S+ RS P P P PPG P +
Sbjct: 221 PQGPPPQGD-NKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--- 276
Query: 411 RGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPP 470
P PG P Q G + SSR P P P PPP
Sbjct: 277 ---PPPPGKPQGPPPQG-----------GSKSRSSRSP-------------PGKPQGPPP 309
Query: 471 PPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREG------ 524
+ PPPPP +GP + + +GPP P P P +G
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNK-----------PQGPPPPGKPQGPPPQGGSKSRS 358
Query: 525 FLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP 583
PP Q+ + P PP P + + P GP P PP R P
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP---PRPPQGGRPSRP 414
Score = 80.9 bits (198), Expect = 1e-14
Identities = 111/457 (24%), Positives = 147/457 (32%), Gaps = 113/457 (24%)
Query: 462 PPG-PSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP 520
PPG P PPP + PPPPP +GP + + +GPP P P P
Sbjct: 53 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP-----------QGPPPPGKPQGP 101
Query: 521 HREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARS 580
+G S +P +PP + P GP PPPP
Sbjct: 102 PPQG-------------DKSRSPRSPP----GKPQGPPPQGGNQPQGP---PPPPG---- 137
Query: 581 IDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP--RPRVSFPKTP 638
P PP PQ PP PP P R SP +P+ P+
Sbjct: 138 -KPQGPPPQGGNKPQGPP--------PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 639 EVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANI 698
GPPP P PQ PP G P PP P + Q P D +
Sbjct: 189 NQPQGPPPPP--GKPQGPPPQGGNKPQG-------PPPPGKPQGPPPQG-----DNKSQS 234
Query: 699 MKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTT 758
+ + Q ++ P PP K Q P P + +
Sbjct: 235 ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 294
Query: 759 TTTTATQEEEKKPPP-------ALPPPPPLAKFPPP---SQPQPPPP------PPPSPAS 802
++ + + + PPP PPPP + PPP ++PQ PPP PPP S
Sbjct: 295 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354
Query: 803 LLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQ 862
+S S PG P G PP + QG P
Sbjct: 355 KSRSARS----------------------------PPGKPQG----PPQQEGNNPQGPPP 382
Query: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
P+ + Q P A + + P G P++PP
Sbjct: 383 PAGGNPQQ---PQAPPAGQPQGPPRPPQGG-RPSRPP 415
Score = 66.6 bits (161), Expect = 2e-10
Identities = 90/374 (24%), Positives = 114/374 (30%), Gaps = 95/374 (25%)
Query: 538 QDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDP 597
Q + P PP+P + P GP PPPP P PP PQ P
Sbjct: 42 QGGNKPQGPPSPP-GKPQGPPPQGGNQPQGP---PPPPG-----KPQGPPPQGGNKPQGP 92
Query: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVP 657
P PP +P+ P P+ ++P PG P GP P
Sbjct: 93 P-----------PPG-----------KPQGPPPQGDKSRSPRSPPGKPQGP--------P 122
Query: 658 PGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEA 717
P G P +GP PP P + Q P +
Sbjct: 123 PQGGNQP-QGP-----PPPPGKPQGPPP------------------------------QG 146
Query: 718 GVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP 777
G PQ P P Q P P + ++ + + P PP
Sbjct: 147 GNKPQGP--PPPGKPQGPPPQGDNKSRSS--------RSPPGKPQGPPPQGGNQPQGPPP 196
Query: 778 PPPLAKFPPP---SQPQPPPPP-----PPSPASLLKSLASVLEGQKYCYRGTGAAVSTRP 829
PP + PPP ++PQ PPPP PP A G+ G P
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256
Query: 830 GPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPV 889
P P P P G P PQ + S S S G P + G +P
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316
Query: 890 PGPMTPTQP--PPP 901
P P +P PPP
Sbjct: 317 GPPPPPGKPQGPPP 330
Score = 61.2 bits (147), Expect = 8e-09
Identities = 80/350 (22%), Positives = 108/350 (30%), Gaps = 64/350 (18%)
Query: 772 PPALPPPPPLAKFPPP---SQPQPPPPP--PPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
P PPPP + PPP ++PQ PPPP P P +G K R +
Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP---------QGDKS--RSPRSPPG 116
Query: 827 TRPGPLP---TTQYSPGPPSGATALPPTSAAPSAQGSPQPSA----------SSSSQFST 873
GP P P PP G PP QG P P S S S
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
Query: 874 SGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSAT 933
G P + G +P P P +P P PP + G
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGP---PP--------------------QGGNKPQ 213
Query: 934 DPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDS 993
P P P G + + G G+ Q + +
Sbjct: 214 GPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN----QPQGPPPPPGKPQGPPPQ 269
Query: 994 VGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPP 1053
G +P+ K + P + G+ S G+ + P GG PP P P
Sbjct: 270 GGNKPQGPPPPGKPQGPPPQG----GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 1054 SAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKL-RSLSEGPPKE 1102
P P P PGK + P P G S++ + +GPP++
Sbjct: 326 QGPPPQGGNKPQGPPPPGK---PQGPPPQGGSKSRSARSPPGKPQGPPQQ 372
Score = 52.0 bits (123), Expect = 5e-06
Identities = 115/517 (22%), Positives = 153/517 (29%), Gaps = 156/517 (30%)
Query: 582 DPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVG 641
+P PP PQ PP +PP +P+ P P+ P+ G
Sbjct: 35 NPQGAPPQGGNKPQGPP----------SPPG-----------KPQGPPPQGG--NQPQ-G 70
Query: 642 PGPPPGPLSKAPQPVPPGVGELPARGPRLFDFP--PTPLEDQFEEPAEFKILPDGLANIM 699
P PPPG PQ PP G P +GP P P P D+ P P G
Sbjct: 71 PPPPPGK----PQGPPPQGGNKP-QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG----- 120
Query: 700 KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTT 759
Q ++ P PP K Q P P +
Sbjct: 121 ---------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171
Query: 760 TTTATQEEEKKPPP-------ALPPPPPLAKFPPP---SQPQPPPPP--PPSPASLLKSL 807
++ + + + PPP PPPP + PPP ++PQ PPPP P P
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP----- 226
Query: 808 ASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASS 867
+G + S R PG P G PP QG P P
Sbjct: 227 -----------QGDNKSQSARS--------PPGKPQG----PPPQGGNQPQGPPPPP--- 260
Query: 868 SSQFSTSGGPWARERRAGEEPVPGPMTPTQP--PPPLSLPPARSESEVLEEISRACETLV 925
G P + G +P GP P +P PPP +RS
Sbjct: 261 -------GKPQGPPPQGGNKP-QGPPPPGKPQGPPPQGGSKSRS---------------- 296
Query: 926 ERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRR 985
S + P P P G + PP + G
Sbjct: 297 -----SRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGP--------------------- 328
Query: 986 HRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAK 1045
G +P+ K + P + G+ + G+ + P G +
Sbjct: 329 -----PPQGGNKPQGPPPPGKPQGPPPQG----GSKSRSARSPPGKPQGPPQQEGNN--- 376
Query: 1046 PPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082
P P PP+ P QP P A P R G P
Sbjct: 377 -PQGPPPPAGGNPQ-QPQAPPAGQPQGPPRPPQGGRP 411
Score = 46.6 bits (109), Expect = 2e-04
Identities = 77/370 (20%), Positives = 113/370 (30%), Gaps = 81/370 (21%)
Query: 748 AVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSL 807
+VA+ ++ +EE P + P A ++PQ PP PP P
Sbjct: 7 SVALLALSSAQNLNEDVSQEES--PSLIAGNPQGAPPQGGNKPQGPPSPPGKP------- 57
Query: 808 ASVLEGQKYCYRGTGAAVSTRP-GPLPTTQYSPGPPSGATALPPTSAAP-SAQGSPQPSA 865
+G +P GP P GPP P P QG P
Sbjct: 58 -----------QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 866 SSSSQFSTSGGPWARERRAGEEPVPGPMTPTQP--PPPLS-------LPPARSESEVLEE 916
S S S G P + G +P P P +P PPP PP + + +
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166
Query: 917 ISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQ 976
+++ RS+ P P + PP K +
Sbjct: 167 DNKS---------RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-------------- 203
Query: 977 KEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQ---GREK 1033
P +G K + P K + D +S+ + G+ +
Sbjct: 204 --------------------PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243
Query: 1034 SRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKL- 1092
P GG PP P P P P P PGK + P P G S++ +
Sbjct: 244 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK---PQGPPPQGGSKSRSSRSP 300
Query: 1093 RSLSEGPPKE 1102
+GPP +
Sbjct: 301 PGKPQGPPPQ 310
Score = 34.7 bits (78), Expect = 0.80
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 2/73 (2%)
Query: 191 KRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRR-RGCNSEQTGLPPGLPLPPP 249
K GPP + ++ + PP GP +EG +P G G N +Q PP P
Sbjct: 344 KPQGPPPQGGSKSRSARS-PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402
Query: 250 PLPPPPPPPPPPP 262
P PP P PP
Sbjct: 403 PRPPQGGRPSRPP 415
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 102 bits (253), Expect = 4e-21
Identities = 154/600 (25%), Positives = 220/600 (36%), Gaps = 96/600 (16%)
Query: 538 QDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSP-AQNPQD 596
+++ PP P TP S S+SP P+ PPPP + S PLP PP P AQ Q+
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV--SPPPLPSPPPPPAQEEQE 454
Query: 597 ---PPLVPLTLAL----PPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGP---GPPP 646
PP+VP T + PP PS + + PE P P T GP P
Sbjct: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAAR-AGPEGTSPPTPTPSTATGGPPEDSPTV 513
Query: 647 GP-----LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKM 701
P L Q + P V AR R+ P +++ +P + ++ P +++
Sbjct: 514 APKSTTFLKNIRQFIMPVVS---ARSSRVIKTPRRFMDEDPPKPPKVEVSP-----VLR- 564
Query: 702 LDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTT 761
+ PP+ + A + SP T P+T P + T
Sbjct: 565 ---------------PPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTF 609
Query: 762 TATQEEEKKPPPALPPPPPLAKFPPP----SQPQP----PPPPPPSPASLLKSLASVLEG 813
T + PPP PPPP A PPP S +P P PS A LK SVL
Sbjct: 610 RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAH-LKIYESVLTP 668
Query: 814 QKYCYRGTGAAVSTRPGPLPTTQYSPGPPS----GAT---ALP--------PTSAAPSAQ 858
GA + P P P SP P G T +LP P A S
Sbjct: 669 PP-----LGAPEAPEPEP-PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPH 722
Query: 859 GSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP-PLSLPP---ARSESEVL 914
G+P S +Q A + + + +P P QPPP P +PP AR
Sbjct: 723 GAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGS 782
Query: 915 EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKR 974
+S E + + R+ + + + L P Q +E AG V +S
Sbjct: 783 LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPV 842
Query: 975 RQKEHQKEHRRHRRACKDSVGRRPR-------------EGRAKAKAKVPKEKSRRVLGNL 1021
R ++ E +R R + +S + PR + RA VP+ + +
Sbjct: 843 RSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQ 902
Query: 1022 DLQSEEIQGREKSRPDLGGASKAKPPTA-PAPPSAPAPSAQPT--PPSASVP---GKKAR 1075
DL +E+ ++ + + K A P S P S P S+P GKK R
Sbjct: 903 DLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMR 962
Score = 91.7 bits (226), Expect = 6e-18
Identities = 136/509 (26%), Positives = 174/509 (34%), Gaps = 144/509 (28%)
Query: 236 EQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERK 295
E+ LPP PP P PPPP PPP PP P L PP ++ P L S
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPSTSPP-PPLCPPPPPPVSPPPLPSP----------- 444
Query: 296 GSAPPERQEQRHSLPHPYPYPAPAYTAHPP-------GHRLVPAAPPGPGPRPPGAESHG 348
PP ++EQ S P P PP A P G P P +
Sbjct: 445 -PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPST-- 501
Query: 349 CLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNT 408
AT P D +V+P +TT P S+ SS T
Sbjct: 502 ---ATGGPPED-----------SPTVAPKSTTFLKNIRQFIMP-----VVSARSSRVIKT 542
Query: 409 GLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSP 468
R ++ +P P P +EVS P L P T PP P P
Sbjct: 543 PRRFMDEDPPKP-------PKVEVS--------------PVLRPPITTS----PPVPQEP 577
Query: 469 PPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH-REGFLG 527
P P P R P PP+ P PLP R L
Sbjct: 578 APVPSPP--RAPTPPS------------------------------TPVPLPEKRRSILR 605
Query: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587
P R++ T++ PP PP P PPPP P P P
Sbjct: 606 EPTFRWTSLTRE--LPPPPPAP----------------------PPPP------APSP-P 634
Query: 588 PSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647
P+PA + + PL L P PS H S P P + P+ PE P PPP
Sbjct: 635 PAPATSSRR----PLLLRAPQFTPSEAHLKIYESVLTP----PPLGAPEAPE--PEPPPA 684
Query: 648 PLSKAPQPVPPGVGELPARG-PRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESI 706
S A +P P VG PR TP++ + P L +G ++L + +
Sbjct: 685 DDSPA-EPEPRAVGRTNHLSLPRFAPVVTTPVKAEV-SPHGAPALSNGPQTQAQLL-QPL 741
Query: 707 RKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
+ + Q +A PQP L+ P + Q P
Sbjct: 742 QALQTQLLPQALPPPQPQLQPPPSPQQMP 770
Score = 87.4 bits (215), Expect = 1e-16
Identities = 183/745 (24%), Positives = 241/745 (32%), Gaps = 128/745 (17%)
Query: 448 PFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAW---LKGPACRAAREDGEILEEL 504
P L PA +P LPP +SPPPP C PPPPP L P A+E+ E
Sbjct: 404 PPLTPPAPSPPPPLPPPSTSPPPPLC----PPPPPPVSPPPLPSPPPPPAQEEQE----- 454
Query: 505 FFGTEGPPRPAPPPLPHREGFLGPP------ASRFSVGTQDSHTPPTPPTPTTSSSNSNS 558
E PP P + G PP A R + T P PTP+T++
Sbjct: 455 ----ESPPPVVPATCSRKRG--RPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPE 508
Query: 559 GSHSSSPAGPV------SFPPPPYLARS--IDPLPR------PPSPAQNPQDPPLVPLTL 604
S + +P F P ARS + PR PP P + P L P
Sbjct: 509 DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPIT 568
Query: 605 ALPPAP------PSSCHQNTSGSFRRPESPRPRVSFPKTPEVG--------PGPPPGPLS 650
PP P PS T S P P R S + P P PPP P
Sbjct: 569 TSPPVPQEPAPVPSPPRAPTPPSTPVP-LPEKRRSILREPTFRWTSLTRELPPPPPAP-P 626
Query: 651 KAPQPVPPGVGELPARGPRLFDFPP-TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKE 709
P P PP +R P L P TP E A KI L E+ +
Sbjct: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSE------AHLKIYESVLTPPPLGAPEA-PEP 679
Query: 710 EEQQQHEAGVAPQPPL--KEPFASLQSPFPTDTAPTTT------APAVAVTTTTTTTTTT 761
E ++ P+P + SL P T P APA++ T
Sbjct: 680 EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ 739
Query: 762 TATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGT 821
+ + P ALPPP P + PPPS Q PP A + S +E + +
Sbjct: 740 PLQALQTQLLPQALPPPQPQLQ-PPPSPQQMPPLEKARIAGVGSLPLSGVEEKMF----- 793
Query: 822 GAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWA-R 880
+ Q + + L P G+ + + S A R
Sbjct: 794 SLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKR 853
Query: 881 ERRAG-EEPVPGP------------------MTPTQPPPPLSLPPARSESEVLEEISRAC 921
ER +G E PV GP M P P +LP + E+ S A
Sbjct: 854 ERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSAS 913
Query: 922 ET--LVERVGRSATDPADPVDTAEPADSG------TERLLPPAQAKEEAGGVAAVSGSCK 973
ET + R R + A P +EP SG R LP K+ C
Sbjct: 914 ETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCL 973
Query: 974 RRQKEHQKEHRRHRRACKDSVG--RRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGR 1031
R Q C V +P+ G K + + + ++I+ R
Sbjct: 974 RVQD------------CGSCVNCLDKPKFGGPNTKKQCCVYR----------KCDKIEAR 1011
Query: 1032 EKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLK 1091
+ R G + K +P S P P REE PG D L
Sbjct: 1012 KMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLL 1071
Query: 1092 LRSLSEGPPKELKIRLIKVESGDKE 1116
R + K+ I +S D E
Sbjct: 1072 QRKSARRCVKQRPSYDIFEDSDDSE 1096
Score = 76.3 bits (186), Expect = 2e-13
Identities = 181/740 (24%), Positives = 237/740 (32%), Gaps = 183/740 (24%)
Query: 335 PGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP 394
P P PPG E PG+ R S +Q +D + P + +A P P
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQN--LDPPLRPDSGSA----PPPAPRSFS 1861
Query: 395 GTTTSSSSSSSSNTGLRGVE----PNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFL 450
G + S S L GV P+PG P + ++HH P +
Sbjct: 1862 GARIKVPNYSPSRRPLGGVSFGPLPSPGSPSS---------LTHH-----------IPTV 1901
Query: 451 GAP--AATPHLSLPPGPSSPPPPPC----PRL-----LRPPPPPAWLKGPACRAAREDGE 499
G P A P S P P +P PPP P L LR PPP + + GE
Sbjct: 1902 GDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTA----LTPTSGE 1957
Query: 500 ILEELFFGTEGPPRPAPPPLPHREGFLGPP------ASRFSVGTQDSHTPPTPPTP---- 549
+ PP PAP P P + LGP S S D P
Sbjct: 1958 L---------APPGPAPSPPPPED--LGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEE 2006
Query: 550 -----TTSSSNSNSGSHSSSPAGPVS----FPPPPYLARSIDPLPRPPSP---------- 590
SS+ G S + P S FP A + P P +P
Sbjct: 2007 IVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDD 2066
Query: 591 -AQNPQDPPLVPLTLALPPAPPSSCHQNTSGSF----RRPES-PRPRVSFPKTPEVGPG- 643
+ + P PP+ P G+ R PE P V F GPG
Sbjct: 2067 GTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGD 2126
Query: 644 ----------PPPGPLSKAPQPVPPGVGELPAR------------GPRLFDFPPTPLEDQ 681
PP PL+ QP G+ PA G R+ P P +
Sbjct: 2127 GGAGPREESLPPAPPLANGSQP-SQGLTASPADPTRTFAWLPGAPGVRVLSLGPAP---E 2182
Query: 682 FEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTA 741
+PA KI+ L N + + + E G PP+K+P P P
Sbjct: 2183 PPKPATSKII---LVNKLGQVFVKMAGE--------GEPVPPPVKQP------PLP---- 2221
Query: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPA 801
P ++ T T+ T LPP P L P +P PPPPP P
Sbjct: 2222 -----PTISPTAPTSWT----------------LPPGPLLGVLPVVGVVRPAPPPPPPPL 2260
Query: 802 SLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSP 861
+L+ S ++ + S R P P PP A L A ++ +P
Sbjct: 2261 TLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-------PPYKAPRLDEDGEA--SEDTP 2311
Query: 862 QPSASSSSQFS-------TSGGPWARER---RAGEEPVPGPMTPTQP--PPPLSLPPARS 909
Q S FS T G +R AGEE PGP+ P P P PP
Sbjct: 2312 QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEES-PGPLQERSPLLPLPEDGPPQVP 2370
Query: 910 ESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVS 969
+ + S +P P D A T L + E+ V A S
Sbjct: 2371 DGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAES 2430
Query: 970 -GSCKRRQKEHQKEHRRHRR 988
R E +E R H R
Sbjct: 2431 LEGAWRTLIEKVQEARGHAR 2450
Score = 62.4 bits (150), Expect = 4e-09
Identities = 169/737 (22%), Positives = 238/737 (32%), Gaps = 146/737 (19%)
Query: 497 DGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSH-TPPTPP-------- 547
DGE EE F G AP L L R G H T P PP
Sbjct: 115 DGESDEEEFQGFHSDEDVAPSSL---RSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAP 171
Query: 548 TP--TTSSSNSNSGSH------------SSSPAGPVSF---PPPPYLARSIDPLPRPPSP 590
TP T + G+ + +P P S P P +R P RP P
Sbjct: 172 TPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPP-GRPAGP 230
Query: 591 AQNPQDPPLVP---LTLALP-PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPP 646
+ Q +V +T+ P P PP ++ +GS++ E P P P+
Sbjct: 231 CRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGR 290
Query: 647 GPLSKAPQPVPPGVGELPARGPRL----FDFPPTPLEDQFEEPAEFKILPD-------GL 695
G + P V + +R ++ + Q + ++ +P G
Sbjct: 291 GGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGG 350
Query: 696 ANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTT 755
+ K ++ + EEE+++ E + KE A + P P +T
Sbjct: 351 SPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPP- 409
Query: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPP---SQPQPPPPPPPSPASLLKSLASVLE 812
A PPP+ PPPPL PPP P P PPPPP+ +S V+
Sbjct: 410 -------APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Query: 813 GQKYCYRGTGAAVST----------RPGPLPTTQYSPGPPSGATALPPTSAAPSAQGS-- 860
C R G T R GP T+ +P PS AT PP + A S
Sbjct: 463 AT--CSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP-TPSTATGGPPEDSPTVAPKSTT 519
Query: 861 ----------PQPSASSSSQFSTS--------------------GGPWARERRAGEEPVP 890
P SA SS T P +EP P
Sbjct: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
Query: 891 GPMTPTQPPPPLSLP---PARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADS 947
P P P PP S P P + S + E R E P P + PA +
Sbjct: 580 VPSPPRAPTPP-STPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA 638
Query: 948 GTER-----------------------LLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHR 984
+ R L PP EA + E R
Sbjct: 639 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPAD----DSPAEPEPR 694
Query: 985 RHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKA 1044
R S+ R KA+V + + Q++ +Q + + L +A
Sbjct: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQL--LPQA 752
Query: 1045 KPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELK 1104
PP P P P PS Q PP +KAR G +S + K+ SL K K
Sbjct: 753 LPP--PQPQLQPPPSPQQMPPL-----EKARIAGVGSLPLSGVEE-KMFSLL----KRAK 800
Query: 1105 IRLIKVESGDKETFIAS 1121
++L K++ ++ AS
Sbjct: 801 VQLFKIDQQQQQKVAAS 817
Score = 62.0 bits (149), Expect = 5e-09
Identities = 152/644 (23%), Positives = 195/644 (30%), Gaps = 202/644 (31%)
Query: 177 WNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEG------LSPGGKRR 230
W + R +G + ++ A E + P + P GE+ L PG R
Sbjct: 1775 WYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER 1834
Query: 231 RGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPP-----------------PPLPGLATSPP 273
P L PP P PPP P PL G++ P
Sbjct: 1835 HS---------PIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGP- 1884
Query: 274 FQLTKPGLWSTL-HGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHP-----PGH 327
L PG S+L H + APP R + L P P P+ A P P
Sbjct: 1885 --LPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA---PRPPPSRWASPPLKTSPQL 1939
Query: 328 RLVP--------------AAPPGPGPRPPGAESHG---------------------CLPA 352
R+ P APPGP P PP E G L
Sbjct: 1940 RVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLG 1999
Query: 353 TRP-----------------PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP- 394
T P PG E SR P + APS PG P
Sbjct: 2000 TEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIH--FPVTVVSAPGLAPSATPGAPR 2057
Query: 395 -----GTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKP- 448
G + S + + RG P PG V G LG + +R P
Sbjct: 2058 IEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPG----------VVRAGVLGAAGDRARPPE 2107
Query: 449 ------------FLGAP----AATPHLSLPPGPS-SPPPPPCPRLLRPPPPP----AWLK 487
LG P A SLPP P + P L P P AWL
Sbjct: 2108 DLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLP 2167
Query: 488 G-PACRA-----AREDGE----------ILEELFFGTEGPPRPAPPPLPHREGFLGPPAS 531
G P R A E + L ++F G P PPP+
Sbjct: 2168 GAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQ---------- 2217
Query: 532 RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPA 591
PP PPT SP P S+ PP + P+ PA
Sbjct: 2218 -----------PPLPPT--------------ISPTAPTSWTLPPGPLLGVLPVVGVVRPA 2252
Query: 592 QNPQDPPLVPLTLALPPAPPSSC---HQNTSGSFRRPESPRPRVSFPKTPEVG------- 641
P PPL + + P +PP + ++ S R P +P P P+ E G
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP-PPYKAPRLDEDGEASEDTP 2311
Query: 642 --PGPPPGPLSKAPQPVPP--GVGELPARGPRLFDFPPTPLEDQ 681
PG G S+ P GV +L G + P PL+++
Sbjct: 2312 QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQER 2355
Score = 55.5 bits (132), Expect = 4e-07
Identities = 56/169 (33%), Positives = 67/169 (39%), Gaps = 32/169 (18%)
Query: 195 PPVKRAAEPPVVQ-----PVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLP--LP 247
PP+ PPV Q P PP A + PS L ++RR E T L LP
Sbjct: 565 PPI--TTSPPVPQEPAPVPSPPRAPTPPSTPVPLP---EKRRSILREPTFRWTSLTRELP 619
Query: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLW-STLHGDAWGPERKGSAPPERQEQR 306
PPP P PPPPP P PPP P ++ P L P S H + E + PP +
Sbjct: 620 PPP-PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIY--ESVLTPPPLGAPE- 675
Query: 307 HSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRP 355
P P P PA +P P PR G +H LP P
Sbjct: 676 --APEPEPPPA-------------DDSPAEPEPRAVGRTNHLSLPRFAP 709
Score = 54.7 bits (130), Expect = 7e-07
Identities = 135/526 (25%), Positives = 169/526 (32%), Gaps = 118/526 (22%)
Query: 196 PVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPP 255
P +R+ P + P PP + S SP R S T L P PP P P
Sbjct: 1909 PPRRSRRPSPLAPRPPPS-RWASPPLKTSPQ-LRVPPPTSVVTALTPTSGELAPPGPAPS 1966
Query: 256 PPPPPPPPP-------LPGLAT-----------SPPFQ--LTKPGLWSTLHGDAWGPERK 295
PPPP P + GL+ + PFQ + G + HG +
Sbjct: 1967 PPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEE 2026
Query: 296 GSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAA-------------PPGPG--PR 340
S+P R P AP+ T P + P G G P
Sbjct: 2027 ESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPS 2086
Query: 341 PPGAESHGCLPA----TRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP-- 394
PG G L A RPP DL V + ++ P S PP P
Sbjct: 2087 GPGVVRAGVLGAAGDRARPP-EDLPSEIV--DFVLKNLGGPGDGGAGPREESLPPAPPLA 2143
Query: 395 -GTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT-PALEVSHHGRLGPSAHSSRKPFLGA 452
G+ S ++S R PG PG PA E P ++ K L
Sbjct: 2144 NGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE--------PPKPATSKIILVN 2195
Query: 453 PAATPHLSLP-PGPSSPPP---PPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGT 508
+ + G PPP PP P + P P +W P G +L L
Sbjct: 2196 KLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPP--------GPLLGVL--PV 2245
Query: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
G RPAPPP P PP + S P +PP ++ S S PA
Sbjct: 2246 VGVVRPAPPPPP-------PPLTLVL-----SSGPASPPRQAIRVKRVSTFSGRSPPA-- 2291
Query: 569 VSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESP 628
PPPY A PR + +D P VP SG F R
Sbjct: 2292 ----PPPYKA------PRLDEDGEASEDTPQVP--------------GLGSGGFSRVRMK 2327
Query: 629 RPRV------SFPKTP--EVGPGP--PPGPLSKAPQPVPPGVGELP 664
P V P P E PGP PL P+ PP V + P
Sbjct: 2328 TPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGP 2373
Score = 54.3 bits (129), Expect = 1e-06
Identities = 86/343 (25%), Positives = 114/343 (33%), Gaps = 47/343 (13%)
Query: 565 PAGPVSFPPPPYLARSIDPLPRPPSPAQNP---QDPPLVPLTLALPPAPPSSCHQNTSGS 621
P GP P A + P+P+ P +DPPL T L P P
Sbjct: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLD--TDVLVPGAPER-------- 1834
Query: 622 FRRPESPRPRVSFPKTPEVGPGPPPGP--LSKAPQPVPPGVGELPARGPRL-FDFPPTPL 678
SP + P P+ G PPP P S A VP P+R P F P P
Sbjct: 1835 ----HSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVP---NYSPSRRPLGGVSFGPLPS 1887
Query: 679 EDQFEEPAEFKILPDGLAN-IMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFP 737
P L + I + D + + + +AP+PP P
Sbjct: 1888 PGS----------PSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP----------PSR 1927
Query: 738 TDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPP 797
+ P T+P + V T+ T T T E P PA PPPP P +
Sbjct: 1928 WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLS 1987
Query: 798 PSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPT-SAAPS 856
+ SL Q+ GA S+ GP +++ P S P T +AP
Sbjct: 1988 AADLDFAASLLGTEPFQEEIV-AAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPG 2046
Query: 857 AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
S P A Q E A ++P G TP P
Sbjct: 2047 LAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP-RGQGTPPSGP 2088
Score = 48.5 bits (114), Expect = 5e-05
Identities = 113/477 (23%), Positives = 144/477 (30%), Gaps = 63/477 (13%)
Query: 193 GGPPVKRAAEPPVVQPVPPAALSG------PSGEEGLSPGGKRRRGCNSEQTGLPPGLPL 246
GGPP + P V P L P S K R E PP + +
Sbjct: 504 GGPP----EDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559
Query: 247 PPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR 306
P PP PP P P P SPP T P L PE++ S E +
Sbjct: 560 SPVLRPPITTSPPVPQEPAP--VPSPPRAPTPPSTPVPL------PEKRRSILREPTFRW 611
Query: 307 HSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQ 366
SL P P PA P PP P P P A S R P S
Sbjct: 612 TSLTRELPPPPPA-----------PPPPPAPSPPPAPATSSRRPLLLRAP--QFTPSEAH 658
Query: 367 RSRMDSSVSPAATTACVPYAPSRPPG--LPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
+S ++P A P PP P + +++ L P P
Sbjct: 659 LKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTP---- 714
Query: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP-----PPPCPRLLRP 479
EVS HG S + L P L P PP PPP P+ + P
Sbjct: 715 ---VKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM-P 770
Query: 480 PPPPAWLKG----PACRAAREDGEILE----ELFFGTEGPPRPAPPPLPHREGFLGPPAS 531
P A + G P + +L+ +LF + + +P L P
Sbjct: 771 PLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMP-----LSPGGQ 825
Query: 532 RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPA 591
V P + S S P PV P ++ R + + A
Sbjct: 826 MEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHA-AVALGQARA 884
Query: 592 QNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGP 648
P+D VP ALP + S ES R K GPG P
Sbjct: 885 MVPED---VPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP 938
Score = 35.0 bits (79), Expect = 0.61
Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 35/168 (20%)
Query: 207 QPVPPAAL-SGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPL 265
+ V P++L S + G +P G+ R+ + PLPPP L P PP P
Sbjct: 130 EDVAPSSLRSALRSQRGRAPRGRGRKHKTT---------PLPPPRLADVAPTPPKTPARK 180
Query: 266 PG----------------LATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ---- 305
G A +P ++ ST P + + P R++Q
Sbjct: 181 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV 240
Query: 306 ---RHSLPHPYPYPAPAYTAHPPGHRLVPAAP-PGPG-PRPPGAESHG 348
++P P P P H G P PGPG PR G S G
Sbjct: 241 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRG 288
Score = 34.3 bits (77), Expect = 1.0
Identities = 28/90 (31%), Positives = 33/90 (36%), Gaps = 8/90 (8%)
Query: 819 RGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPW 878
RG GA GP PGP + L SA + P S S GGP
Sbjct: 1047 RGAGAG-----GPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPP 1101
Query: 879 ARERRAGEE---PVPGPMTPTQPPPPLSLP 905
A RR E P+P P ++P P P
Sbjct: 1102 APRRRTPRENELPLPEPEEQSRPRKPTLQP 1131
Score = 32.3 bits (72), Expect = 4.0
Identities = 35/146 (23%), Positives = 57/146 (39%), Gaps = 5/146 (3%)
Query: 1046 PPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVS-RADMLKLRSLSEG--PPKE 1102
PP P+PP PA Q P VP +R+ P S RA+ R+ EG PP
Sbjct: 438 PPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497
Query: 1103 LKIRLIKVESGDKETFI-ASEVEERRLRMADL-TISHCAADVVRASRNAKVKGKFRESYL 1160
D T S + +R + +S ++ V++ R + + +
Sbjct: 498 TPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKV 557
Query: 1161 SPAQSVKPKINTEEKLPREKLNPPTP 1186
+ ++P I T +P+E P+P
Sbjct: 558 EVSPVLRPPITTSPPVPQEPAPVPSP 583
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 102 bits (253), Expect = 4e-21
Identities = 116/423 (27%), Positives = 153/423 (36%), Gaps = 51/423 (12%)
Query: 242 PGLPLPPPPLPPPPPP---PPPPPPPLPGLAT-SPPFQLTKPGLWSTLHGDAWGPERKGS 297
P P PPPPLPPPPPP PPPPPP P ++T + + P S L D R
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Query: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG 357
Q S P + + PP G G P RP G
Sbjct: 62 VT---QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGG-----FPVLRPAG 113
Query: 358 S-DLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPN 416
D+ + + + SP + P PP P +S + ++ T P
Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRLPNKTIS-GPLIPPASPRLGNTSEAHGAARTA----PPR 168
Query: 417 PGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLP----PGPSSPPPPP 472
P +P P L PS+ + P + P +LP P P +PPPPP
Sbjct: 169 PNVPAPPPPTPPPPPPPLPPPL-PSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227
Query: 473 CPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASR 532
P PPP P L + + + L L PP P PP + G PAS
Sbjct: 228 PP----PPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY-PGLKAEPAS- 281
Query: 533 FSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQ 592
QD+ PP PP P + S SP + PP P + S + P P +
Sbjct: 282 ---PAQDAQEPPAPPPPLPPYA-------SCSPRASLPAPPLPGVNSSSETPPPLPPKSP 331
Query: 593 NPQDPPLVPLTLAL--PPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLS 650
+ Q PP AL PPAPP S +P + R P PPP P +
Sbjct: 332 SFQAPPQKAGAQALPAPPAPPGS----------QPFLQKKRHGRPGAGGGKLNPPPAPPA 381
Query: 651 KAP 653
++P
Sbjct: 382 RSP 384
Score = 92.0 bits (227), Expect = 4e-18
Identities = 140/528 (26%), Positives = 175/528 (33%), Gaps = 148/528 (28%)
Query: 54 PPLPAPLPPSHGSSSGHPSKPYYAPGAPTPR--PLHGKLESLHGCV----QALLREPAQP 107
PP P PLPP P P AP P P P+ SL ALL + Q
Sbjct: 5 PPPPPPLPP--------PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQG 56
Query: 108 GLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRA 167
++ Q+ + E+++ + GG A G L + G
Sbjct: 57 TRLRKVTQINDRSAPQIESSK---GTNKEGGGSANTR---GASTPPTLGDLFAGGFP--- 107
Query: 168 KVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGG 227
VL P Q + G K G P RA P + P +SGP L P
Sbjct: 108 -VLRPAGQ---------RDVAGGKTGQGPGSRAPSPRL----PNKTISGP-----LIPPA 148
Query: 228 KRRRGCNSEQTGLP------PGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGL 281
R G SE G P +P PPPP PPPPPPP PPP P +P L P
Sbjct: 149 SPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTP---LVSPP- 204
Query: 282 WSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRP 341
GP KG+ P PP VP APP P P P
Sbjct: 205 ---------GPLTKGNLP---------------------VVAPP----VPCAPPPPPPPP 230
Query: 342 PGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSS 401
P P PP S L D +V P +P P P LP
Sbjct: 231 PPT------PPPLPPASVL---------SDKAVKPQLAPLHLPPIPPPLPLLP------- 268
Query: 402 SSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSL 461
G G++ P P D + PA P P+ S
Sbjct: 269 -----PCGYPGLKAEPASPAQDAQEPPA---------------------PPPPLPPYASC 302
Query: 462 PPGPSSPPPP-PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLP 520
P S P PP P PPP K P+ +A + G + PAPP P
Sbjct: 303 SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA--------GAQA--LPAPPAPP 352
Query: 521 HREGFLGPPA-SRFSVGTQDSHTPPTPP--TPTTSSSNSNSGSHSSSP 565
+ FL R G + PP PP +PTT S+ + + + +P
Sbjct: 353 GSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTP 400
Score = 75.9 bits (185), Expect = 3e-13
Identities = 109/405 (26%), Positives = 134/405 (33%), Gaps = 90/405 (22%)
Query: 309 LPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRS 368
+P P P P P PP + A PP P PP + L P G + +Q+
Sbjct: 1 MPVPPPPPPPLPPPPPP----LGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQG 56
Query: 369 RMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTP 428
V+ + S+ T+ S+NT RG P + P
Sbjct: 57 TRLRKVTQINDRSAPQIESSK-------GTNKEGGGSANT--RGASTPPTLGDLFAGGFP 107
Query: 429 ALEVSHH------------GRLGPSAHSSRKPFLG--APAATPHL-----------SLPP 463
L + G PS K G P A+P L + PP
Sbjct: 108 VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP 167
Query: 464 GPSSP-PPPPCPRLLRPP-PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH 521
P+ P PPPP P PP PPP P L + PP P PP P
Sbjct: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP- 226
Query: 522 REGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSP-AGPVSFPPPPYLARS 580
PP PPTP S + P P+ PP P
Sbjct: 227 --------------------PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
Query: 581 IDPL------PRPPSPAQNPQDPPLVPLTLALPPAPP-SSCHQNTSGSFRRPESPRPRV- 632
+ P P SPAQ+ Q+PP P PP PP +SC S P P P V
Sbjct: 267 LPPCGYPGLKAEPASPAQDAQEPPAPP-----PPLPPYASCSPRAS----LPAPPLPGVN 317
Query: 633 SFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTP 677
S +TP P PP P +AP P G LPA PP P
Sbjct: 318 SSSETPP--PLPPKSPSFQAP-PQKAGAQALPA--------PPAP 351
Score = 73.6 bits (179), Expect = 2e-12
Identities = 134/531 (25%), Positives = 177/531 (33%), Gaps = 115/531 (21%)
Query: 453 PAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGE--ILEELFFGT-- 508
P P L PP P PPPP P PP + R A G +L ++ GT
Sbjct: 5 PPPPPPLPPPPPPLGAPPPP-----PPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
Query: 509 --------EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPT--------------- 545
P+ ++EG S T+ + TPPT
Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEG-------GGSANTRGASTPPTLGDLFAGGFPVLRPA 112
Query: 546 -PPTPTTSSSNSNSGSHSSSP-------AGPVSFPPPPYLARSID-------PLPRPPSP 590
+ GS + SP +GP+ P P L + + PRP P
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172
Query: 591 AQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFP-KTPEV--GPGPPPG 647
A P PP P LPP PSS T P P + + P P V P PPP
Sbjct: 173 APPPPTPP--PPPPPLPPPLPSSSPIKT--PLVSPPGPLTKGNLPVVAPPVPCAPPPPPP 228
Query: 648 PLSKAPQPVPP-GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESI 706
P P P+PP V A P+L P+ P +LP +K S
Sbjct: 229 PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI------PPPLPLLPPCGYPGLKAEPASP 282
Query: 707 RKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQE 766
++ ++ AP PPL P+AS P + P P V ++ T
Sbjct: 283 AQDAQEPP-----APPPPL-PPYASCS---PRASLPAPPLPGVNSSSET----------- 322
Query: 767 EEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
PP LPP P + PP P PP+P L G+ G
Sbjct: 323 -----PPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
Query: 827 TRPGPLPTTQYSPGPPSGATALPPTSAAPSAQ---GSPQPSASSSSQFSTSGGPWARERR 883
P PTT+ S ATA PT P Q GS S+F+
Sbjct: 378 APPARSPTTELS-SKSQQATAWTPTQ-QPGGQLRNGSLHIIDDFESKFTF--------HS 427
Query: 884 AGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD 934
+ P P P Q P +P +R+ L+ E VG+S+ D
Sbjct: 428 VEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQ---------AEAVGQSSDD 469
Score = 61.6 bits (148), Expect = 6e-09
Identities = 98/399 (24%), Positives = 127/399 (31%), Gaps = 75/399 (18%)
Query: 583 PLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF-------- 634
P+P PP P P PPL A PP PPS+ +T S R P+ R +
Sbjct: 2 PVPPPPPPPLPPPPPPLG----APPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
Query: 635 --PKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILP 692
K ++ P + + G G RG PPT L D F F +L
Sbjct: 58 RLRKVTQINDRSAP-QIESSKGTNKEGGGSANTRGAST---PPT-LGDLFA--GGFPVL- 109
Query: 693 DGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVT 752
+ Q+ G Q P ++P P T + P +
Sbjct: 110 ---------------RPAGQRDVAGGKTGQGP------GSRAPSPRLPNKTISGPLIPPA 148
Query: 753 TTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSP--ASLLKSLASV 810
+ T+ P P +P PPP PPP P PPP P SP L+ +
Sbjct: 149 SPRLGNTSEAHGAARTAPPRPNVPAPPPPTP-PPPPPPLPPPLPSSSPIKTPLVSPPGPL 207
Query: 811 LEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQ-------P 863
+G V P P P PP LPP S PQ P
Sbjct: 208 TKG--------NLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP 259
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPL-----SLPPARSESEVLEEIS 918
G P + A P P PPPPL P A + L ++
Sbjct: 260 IPPPLPLLPPCGYPGLKAEPA--SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVN 317
Query: 919 RACETLVERVGRSATDPADPVDTAEPADSGTERL-LPPA 956
+ ET P P A P +G + L PPA
Sbjct: 318 SSSET------PPPLPPKSPSFQAPPQKAGAQALPAPPA 350
Score = 31.2 bits (69), Expect = 8.9
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 1041 ASKAKPPTAPAPPSAPAPSAQP--TPPSASVPGKKAREEAPGP 1081
A A+ P AP PP P S P + P+ +PG + E P P
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPP 325
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 101 bits (252), Expect = 5e-21
Identities = 163/641 (25%), Positives = 204/641 (31%), Gaps = 141/641 (21%)
Query: 208 PVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPG 267
P PP GP G GL PG R G NS P GLP P PP P P PP PG
Sbjct: 905 PGPP----GPPGVPGL-PGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPG 959
Query: 268 LATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGH 327
PP + + G G+A P KGS P P + A PG
Sbjct: 960 -REGPPGRTGQKGSL----GEAGAPGHKGS---------KGAPGPAGARGESGLAGAPG- 1004
Query: 328 RLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAP 387
PA PPGP P PPG G P G D M+ S P +TA P
Sbjct: 1005 ---PAGPPGP-PGPPGPPGPGL-----PAGFD---------DMEGSGGPFWSTARSADGP 1046
Query: 388 SRPPGLPGTT----TSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH 443
PPGLPG + G GV PG+PG + P G G
Sbjct: 1047 QGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGD 1106
Query: 444 SSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEE 503
K +G P PGP PP GP + +DG +L
Sbjct: 1107 PG-KDGVGQPGL-------PGPPGPP------------------GPVVYVSEQDGSVLSV 1140
Query: 504 LFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSS 563
P P P GF GP + ++G++ P P GS S
Sbjct: 1141 ----------PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGP-----KGEKGEPGSIFS 1185
Query: 564 SPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFR 623
G + P A+ PP P P + P P G
Sbjct: 1186 PDGGALG--PAQKGAKGEPGFRGPPGPYGRPG----YKGEIGFPGRPGRPGMNGLKGEKG 1239
Query: 624 RPESPRPRVSF-----PKTPEVGPGPPPGPL------SKAPQPVPPGV----GELPARGP 668
P P P PGPP P+ +++ +P PPG+ G +G
Sbjct: 1240 EPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGA 1299
Query: 669 RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGV--------- 719
+ PP P P +F D L +M E + + Q+ E G
Sbjct: 1300 KGEVGPPGP-------PGQFPF--DFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGS 1350
Query: 720 ----APQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL 775
P PP + + P P E ++ PP
Sbjct: 1351 SLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPG---------PQGPPGIGYEGRQGPPGP 1401
Query: 776 PPPPPLAKFPPP-----SQPQPP-PPPPPSPASLLKSLASV 810
P PP FP P S P PP PP PP P + + + V
Sbjct: 1402 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGV 1442
Score = 92.0 bits (227), Expect = 4e-18
Identities = 191/762 (25%), Positives = 241/762 (31%), Gaps = 173/762 (22%)
Query: 224 SPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLP----GLATSPPFQLTKP 279
+PGG+ + G Q G PG+P PP PP P P PP LP L + P T P
Sbjct: 743 TPGGRVKEGGLKGQKG-EPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVP 801
Query: 280 GLWST--LHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPA----A 333
G G P R G ++ + P +P P G + P
Sbjct: 802 GPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERG 861
Query: 334 PPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTAC-----VPYAPS 388
PPGP PPG PPG R ++ M+ S A P P
Sbjct: 862 PPGP-QGPPG-----------PPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPG 909
Query: 389 RP-----PGLPGTTTSSSSSSSSNTGLRGV---EPNPGIPGADHYQTPALEVSHHGRLGP 440
P PG PG +SS GL GV E PG PG P GR GP
Sbjct: 910 PPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPP------GREGP 963
Query: 441 SAHSSRKPFLGAPAATPH-----------------LSLPPGPSSPPPPPCPRLLRPPPPP 483
+ +K LG A H L+ PGP+ PP PP PP PP
Sbjct: 964 PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPP-----GPPGPP 1018
Query: 484 AWLKGPACRAAREDGEILEELFF-------GTEGPP-------RPAPPPLPHREGFLGPP 529
GP A +D E F+ G +GPP P P LP +G +G
Sbjct: 1019 ----GPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 1074
Query: 530 ASRFSVGTQDSHTPPTPPTPT-TSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP 588
G P P S G G P P P PP
Sbjct: 1075 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGP----------PGPP 1124
Query: 589 SPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGP---- 644
P + L++ P P F P P+ + K PGP
Sbjct: 1125 GPVVYVSEQDGSVLSVPGPEGRPG------FAGFPGPAGPKGNLG-SKGERGSPGPKGEK 1177
Query: 645 -PPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPL-EDQFEEPAEFKILP--DGLANIMK 700
PG + +P G + A+G F PP P ++ F P G+ +
Sbjct: 1178 GEPGSIF-SPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGL-- 1234
Query: 701 MLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTT 760
K E+ + +A + F P P P T
Sbjct: 1235 -------KGEKGEPGDASLG--------FGMRGMPGPPGPPGPPGPPG-------TPVYD 1272
Query: 761 TTATQEEEKKPPPALP----PPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASV------ 810
+ E + PP LP PP P + PP PP P L+ A +
Sbjct: 1273 SNVFAESSRPGPPGLPGNQGPPGPKG---AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGD 1329
Query: 811 -----LEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP--PTSAAPSAQGSPQP 863
+G++ G G S+ PGP PGPP G P P S +G P P
Sbjct: 1330 RGDAGQKGERGEPGGGGFFGSSLPGP-------PGPP-GPRGYPGIPGPKGESIRGQPGP 1381
Query: 864 SASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
GP G E GP P PP P S P
Sbjct: 1382 PGPQ--------GP----PGIGYEGRQGPPGPPGPPGPPSFP 1411
Score = 74.3 bits (181), Expect = 9e-13
Identities = 133/507 (26%), Positives = 174/507 (34%), Gaps = 105/507 (20%)
Query: 216 GPSGEEGLS--PGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPP--PPLPGLATS 271
G G EG++ G K RG E+ G P + P LP PP PP P G S
Sbjct: 1081 GLPGREGIAGPQGPKGDRGSRGEK-GDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLS 1139
Query: 272 PPFQLTKPGLWSTLHGDAWGP--------ERKGSAPPERQEQRHSLPHPYPY---PAPAY 320
P +PG ++ G A GP ER P + + S+ P PA
Sbjct: 1140 VPGPEGRPG-FAGFPGPA-GPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKG 1197
Query: 321 TAHPPGHRLVPAAPPGPGPRPPGAESHGCLPAT--RPPGSDLRESRVQRSRMDSSVSPAA 378
PG R PPGP RP G + P RP + L+ + + D+S+
Sbjct: 1198 AKGEPGFR----GPPGPYGRP-GYKGEIGFPGRPGRPGMNGLKGEKGEPG--DASLGFGM 1250
Query: 379 TTACVPYAPSRPPGLPGTTTSSSS--SSSSNTGLRGVEPN---------------PGIPG 421
P P PPG PGT S+ + SS G G+ N PG PG
Sbjct: 1251 RGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPG 1310
Query: 422 ADHYQTPALEVSHHGRLGPSAHSSRKPFLGAP-------AATPHLSLPPGPSSPPPPPCP 474
+ LE G G + +K G P ++ P PPGP P P P
Sbjct: 1311 QFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGP 1370
Query: 475 R--LLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASR 532
+ +R P P +GP + G +GPP P PP P F GP
Sbjct: 1371 KGESIRGQPGPPGPQGPPGIG-----------YEGRQGPPGPPGPPGP--PSFPGPHRQT 1417
Query: 533 FSV-GTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYL-------------- 577
SV G PP PP +SS + + G V P +L
Sbjct: 1418 ISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQ 1477
Query: 578 -------ARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRP 630
+ PLPR PP+V L + S + R E P P
Sbjct: 1478 NGFRKVQLEARTPLPRGTDNEVAALQPPVVQL--------------HDSNPYPRREHPHP 1523
Query: 631 RVSFPKTPEVGPGPPPGPLSKAPQPVP 657
+ ++ PP P PQP P
Sbjct: 1524 TARPWRADDILASPPRLP---EPQPYP 1547
Score = 68.2 bits (165), Expect = 7e-11
Identities = 220/930 (23%), Positives = 270/930 (29%), Gaps = 210/930 (22%)
Query: 216 GPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQ 275
G SG+ G G R L P LP PPP T+PP
Sbjct: 661 GASGDSGSGLGDARELLREETGAALKPRLPAPPP-------------------VTTPPL- 700
Query: 276 LTKPGLWSTLHGDAWGPERKGSAPPERQEQR-------HSLPHPYPYPAPAYTAHPPGHR 328
A G + S E +EQ +LP + PG R
Sbjct: 701 -------------AGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGR 747
Query: 329 LVPAAPPG----PG-PRPPGAES---HGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380
+ G PG P PPG CLP PPG S + PA T
Sbjct: 748 VKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPG--PPGLPCPVSPL------GPAGPALQT 799
Query: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGP 440
P P PPG GT G G + PG G + +V G G
Sbjct: 800 VPGPQGPPGPPGRDGTP-----GRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGD 854
Query: 441 SAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCP-------------------------- 474
R P PGP PP PP P
Sbjct: 855 PGVGERGP--------------PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG 900
Query: 475 -RLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRF 533
R PP P + G R FG P P LP G GPP
Sbjct: 901 PRGFPGPPGPPGVPGLPGEPGR----------FGVNSSDVPGPAGLPGVPGREGPP---- 946
Query: 534 SVGTQDSHTPPTPPT---PTTSSSNSNSGSHSSSPAGPVSFPPP-PYLARSIDPLPRPPS 589
G PP PP P + S + +P S P P AR L P
Sbjct: 947 --GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPG 1004
Query: 590 PAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPE-SPRPRVSFPKTPEVGPGPPPGP 648
PA P PP PP F E S P S ++ + GPP P
Sbjct: 1005 PAGPPG-----------PPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLP 1053
Query: 649 LSKAPQPVP--PGV-GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDES 705
K VP PG GE+ A G + FP P + P P G D
Sbjct: 1054 GLKGDPGVPGLPGAKGEVGADG--VPGFPGLPGREGIAGPQG----PKG--------DRG 1099
Query: 706 IRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ 765
R E+ + GV QP L P P P V V+ + +
Sbjct: 1100 SRGEKGDPGKD-GVG-QPGLPGP-------------PGPPGPVVYVSEQDGSVLSVPGP- 1143
Query: 766 EEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAV 825
E +P A P P K S+ + P P S+ S G G A
Sbjct: 1144 --EGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGG------ALGPAQ 1195
Query: 826 STRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAG 885
G P + PGP G P G P + + G P G
Sbjct: 1196 KGAKGE-PGFRGPPGP-YGRPGYKGEIGFPGRPGRPGMNGLKGEK----GEPGDASLGFG 1249
Query: 886 EEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPA 945
+PGP P PP P P +S V E SR P P + P
Sbjct: 1250 MRGMPGPPGPPGPPGPPGTPVY--DSNVFAESSRP------------GPPGLPGNQGPPG 1295
Query: 946 DSGTERLL----PPAQAKEEAGGVAA-VSGSCKRRQKEHQKEHRRHRRA---CKDSVGRR 997
G + + PP Q + + A + G R QK R S+
Sbjct: 1296 PKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGP 1355
Query: 998 PREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPA 1057
P + +P K + G + P +G + PP P PP P+
Sbjct: 1356 PGPPGPRGYPGIPGPKGESIRGQPGPPGPQ------GPPGIGYEGRQGPPGPPGPPGPPS 1409
Query: 1058 PSAQPTPPSASVPGKKAREEAPGPPGVSRA 1087
P + SVPG PGPPG A
Sbjct: 1410 FPG-PHRQTISVPGPPGPPGPPGPPGTMGA 1438
Score = 62.0 bits (149), Expect = 5e-09
Identities = 165/685 (24%), Positives = 211/685 (30%), Gaps = 106/685 (15%)
Query: 474 PRLLRPPP---PPAWLKGPACRAAREDGEILEELFFGTEGPPR-PAPPPLPHREGFLGPP 529
PRL PPP PP L G + E+ E+ + G P + +G + P
Sbjct: 687 PRLPAPPPVTTPP--LAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTP 744
Query: 530 ASRFSVG-TQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPP 588
R G + P P P + P G P PP L + PL P
Sbjct: 745 GGRVKEGGLKGQKGEPGVPGPPGRAG----------PPGSPCLPGPPGLPCPVSPLG-PA 793
Query: 589 SPA----QNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTP-EVGP- 642
PA PQ PP P P G +P P+ FP TP +VGP
Sbjct: 794 GPALQTVPGPQGPPGPP---GRDGTPGRDGEPGDPGEDGKPGDTGPQ-GFPGTPGDVGPK 849
Query: 643 ---GPPP----GPLSKAPQPVPPGV------------------GELPA-RGPRLFDFPPT 676
G P GP P PPG G+L A RGPR F PP
Sbjct: 850 GDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPG 909
Query: 677 P--LEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQS 734
P + EP F + + AG+ P + P
Sbjct: 910 PPGVPGLPGEPGRFGVNSSDVPG------------------PAGLPGVPGREGPPGFPGL 951
Query: 735 PFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPA-LPPPPPLAKFPPPSQPQPP 793
P P P + + + P PA LA P P+ P P
Sbjct: 952 PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGP 1011
Query: 794 PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGP--LPTTQYSPGPPSGATALPPT 851
P PP P L + +EG + T + GP LP + PG P LP
Sbjct: 1012 PGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPG----LPGA 1067
Query: 852 SAAPSAQGSPQ-PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSE 910
A G P P + GP GE+ PG QP P P
Sbjct: 1068 KGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPV 1127
Query: 911 SEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLP-PAQAKEEAGGVAAVS 969
V E+ P S ER P P K E G + +
Sbjct: 1128 VYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPD 1187
Query: 970 GSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKV--PKEKSRRVLGNLDLQSEE 1027
G ++ K R G GR K ++ P R + L + E
Sbjct: 1188 GGALGPAQKGAKGEPGFR-------GPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE 1240
Query: 1028 IQGREKSRPDLGGASKAKPPTAPAPPSAP-------APSAQPTPP----SASVPGKK-AR 1075
G PP P PP P A S++P PP + PG K A+
Sbjct: 1241 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAK 1300
Query: 1076 EEA--PGPPGVSRADMLKLRSLSEG 1098
E PGPPG D L+L + +G
Sbjct: 1301 GEVGPPGPPGQFPFDFLQLEAEMKG 1325
Score = 40.0 bits (92), Expect = 0.019
Identities = 46/188 (24%), Positives = 60/188 (31%), Gaps = 40/188 (21%)
Query: 740 TAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLA---KFPPPSQPQPPPPP 796
T P P T TTT T E P P PP P+ + P P
Sbjct: 44 TIPEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAP 103
Query: 797 PPSPASLLKSLASVLEG-------------QKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
+ A + + +V +G + R + T GPL S P
Sbjct: 104 EENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQE 163
Query: 844 GATALPPTSAAPSAQGS--------PQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTP 895
T L P+ PS+ G+ P P+ S S G PWA P+T
Sbjct: 164 NGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPS----LGRPWA------------PLTG 207
Query: 896 TQPPPPLS 903
PPP S
Sbjct: 208 PSVPPPSS 215
Score = 38.9 bits (89), Expect = 0.043
Identities = 79/277 (28%), Positives = 93/277 (33%), Gaps = 65/277 (23%)
Query: 208 PVPPAALSGPSGEEGL-SPGGKRRRGCNSEQTGLPPGLPLPPPPLP------PPPPPPPP 260
P PP GP G G+ P G+ RG Q G PPG P PP + PP PP PP
Sbjct: 1353 PGPPGP-PGPRGYPGIPGPKGESIRG----QPG-PPG-PQGPPGIGYEGRQGPPGPPGPP 1405
Query: 261 PPPPLPG------LATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPY- 313
PP PG PP PG T+ A R + Q H +P +
Sbjct: 1406 GPPSFPGPHRQTISVPGPPGPPGPPGPPGTM--GASSGVRLWATRQAMLGQVHEVPEGWL 1463
Query: 314 ---PYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRM 370
Y G R V P PR E + A +PP L +S R
Sbjct: 1464 IFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNE----VAALQPPVVQLHDSNPYPRR- 1518
Query: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT--- 427
P A + PP LP EP P PGA H+ +
Sbjct: 1519 -EHPHPTARPWRADDILASPPRLP-------------------EPQP-YPGAPHHSSYVH 1557
Query: 428 --PALEVSHHGRLGPSAHSSR--KPFLGAPAATPHLS 460
PA S P AHS R +P L A LS
Sbjct: 1558 LRPARPTS------PPAHSHRDFQPVLHLVALNSPLS 1588
Score = 35.0 bits (79), Expect = 0.61
Identities = 77/313 (24%), Positives = 100/313 (31%), Gaps = 75/313 (23%)
Query: 208 PVPPAALSGPSG---EEGL----------SPGGKRRR-GCNSEQTGLPPGLPLPPPPLPP 253
PV P AL+GPS E G SPG G T PP L P PL
Sbjct: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTG 207
Query: 254 PPPPPPPPPPPLPG--LATSPPFQLTKPGLWSTLHGDAWGPERKGSAP----PERQEQRH 307
P PPP L +PP W +L P+ +G +P P +Q QR
Sbjct: 208 PSVPPPSSGRASLSSLLGGAPP--------WGSLQ----DPDSQGLSPAAAAPSQQLQRP 255
Query: 308 SLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQR 367
+ P P H AAP PGA S + R+S
Sbjct: 256 DVRLRTPLLHPLVMGSLGKH----AAPSAFSSGLPGALSQVAVTTL------TRDSGAWV 305
Query: 368 SRMDSSVSP--AATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHY 425
S + +SV P A +A + P P G R + P +P H
Sbjct: 306 SHVANSVGPGLANNSALLGADPEAPAG------------------RCLPLPPSLPVCGHL 347
Query: 426 QTPALEVSH--HGRLGPSAHSSRKPFLGAPAATPH---------LSLPPGPSSPP--PPP 472
+ + H G + + + G H L +PP S PP PPP
Sbjct: 348 GISRFWLPNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPP 407
Query: 473 CPRLLRPPPPPAW 485
C + W
Sbjct: 408 CCQFCEALQDACW 420
Score = 34.3 bits (77), Expect = 1.0
Identities = 22/72 (30%), Positives = 25/72 (34%), Gaps = 10/72 (13%)
Query: 1039 GGASKAKPPTAPAPPSAPAPSAQPTPPS----------ASVPGKKAREEAPGPPGVSRAD 1088
G + PP P P P P + PP A PG K + APGP G
Sbjct: 938 GVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGES 997
Query: 1089 MLKLRSLSEGPP 1100
L GPP
Sbjct: 998 GLAGAPGPAGPP 1009
Score = 32.7 bits (73), Expect = 3.1
Identities = 44/191 (23%), Positives = 69/191 (36%), Gaps = 24/191 (12%)
Query: 628 PRPRVSFPKTPEVGPGPPPGPLSKAPQPVP-PGVGELPAR-------GPRLFDFPPTPLE 679
P P+ P P P + + +P PG E P+ P + P P E
Sbjct: 46 PEPQGPLPVQPTADTTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEE 105
Query: 680 DQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTD 739
+ AE + G+ + +++ ++++ E + A L+ P L P+
Sbjct: 106 NIAGVGAEILNVAKGIRSFVQLWNDTVPTESLAR------AETLVLETPVGPLALAGPSS 159
Query: 740 TAP---TTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPP 796
T TT P+ + ++ TT T PA P PP P P PP
Sbjct: 160 TPQENGTTLWPSRGIPSSPGAHTTEAGTL-------PAPTPSPPSLGRPWAPLTGPSVPP 212
Query: 797 PPSPASLLKSL 807
P S + L SL
Sbjct: 213 PSSGRASLSSL 223
Score = 31.2 bits (69), Expect = 8.9
Identities = 31/98 (31%), Positives = 36/98 (36%), Gaps = 12/98 (12%)
Query: 19 LGGLSCAGAWSSCPPHP-----PPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSK 73
+G L+ AG SS P P R G + G P P P PPS G P
Sbjct: 149 VGPLALAGP-SSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPS----LGRPWA 203
Query: 74 PYYAPGAPTPRPLHGKLESLHGCVQ--ALLREPAQPGL 109
P P P P L SL G L++P GL
Sbjct: 204 PLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQGL 241
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 104,506,701
Number of Sequences: 37866
Number of extensions: 8278744
Number of successful extensions: 218027
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1321
Number of HSP's successfully gapped in prelim test: 2545
Number of HSP's that attempted gapping in prelim test: 49209
Number of HSP's gapped (non-prelim): 76715
length of query: 1682
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1566
effective length of database: 13,855,062
effective search space: 21697027092
effective search space used: 21697027092
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.