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Search of human proteins with 27903825
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27903825 APG4 autophagy 4 homolog D [Homo sapiens]
(474 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27903825 APG4 autophagy 4 homolog D [Homo sapiens] 994 0.0
gi|30410846 APG4 autophagy 4 homolog C isoform 8 [Homo sapiens] 409 e-114
gi|30410844 APG4 autophagy 4 homolog C isoform 7 [Homo sapiens] 409 e-114
gi|30795252 autophagy-related cysteine endopeptidase 2 isoform a... 197 2e-50
gi|47132611 APG4 autophagy 4 homolog B isoform a [Homo sapiens] 192 4e-49
gi|30410798 APG4 autophagy 4 homolog B isoform b [Homo sapiens] 192 6e-49
gi|30795248 autophagy-related cysteine endopeptidase 2 isoform b... 142 5e-34
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 36 0.067
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 35 0.11
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 35 0.11
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 35 0.19
gi|41152072 zinc finger, DHHC domain containing 5 [Homo sapiens] 34 0.25
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 34 0.33
gi|119508426 alpha 3 type IX collagen [Homo sapiens] 33 0.43
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 33 0.56
gi|134031945 SCO-spondin [Homo sapiens] 33 0.56
gi|111955326 MLX interacting protein [Homo sapiens] 33 0.74
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 32 0.96
gi|223278377 antimicrobial peptide RY2G5 [Homo sapiens] 32 0.96
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 32 0.96
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 32 0.96
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 32 0.96
gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3 [... 32 0.96
gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens] 32 0.96
gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens] 32 0.96
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 32 0.96
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 32 0.96
gi|118498339 EMI domain containing 2 [Homo sapiens] 32 0.96
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 32 0.96
gi|48762934 alpha 2 type I collagen [Homo sapiens] 32 1.3
>gi|27903825 APG4 autophagy 4 homolog D [Homo sapiens]
Length = 474
Score = 994 bits (2569), Expect = 0.0
Identities = 474/474 (100%), Positives = 474/474 (100%)
Query: 1 MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD 60
MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD
Sbjct: 1 MNSVSPAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD 60
Query: 61 EVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRL 120
EVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRL
Sbjct: 61 EVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRL 120
Query: 121 WLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELS 180
WLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELS
Sbjct: 121 WLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGLGPPELS 180
Query: 181 GSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSG 240
GSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSG
Sbjct: 181 GSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSG 240
Query: 241 KKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSV 300
KKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSV
Sbjct: 241 KKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPTAEWKSV 300
Query: 301 VILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYC 360
VILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYC
Sbjct: 301 VILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYC 360
Query: 361 QPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSS 420
QPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSS
Sbjct: 361 QPTVDVSQADFPLESFHCTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSS 420
Query: 421 ATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL 474
ATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL
Sbjct: 421 ATERYPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL 474
>gi|30410846 APG4 autophagy 4 homolog C isoform 8 [Homo sapiens]
Length = 458
Score = 409 bits (1052), Expect = e-114
Identities = 212/464 (45%), Positives = 289/464 (62%), Gaps = 61/464 (13%)
Query: 60 DEVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGE------------- 106
DEVDK K KF++AWNN+KY WV+K++T FS+ S + L G+ Y F+ E
Sbjct: 7 DEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCT 66
Query: 107 -------GDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLL 159
G+++ F++DF+SR+WLTYR +FP + G LT+DCGWGC LR+GQM+LAQGL+L
Sbjct: 67 IEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLIL 126
Query: 160 HFLPRDWTWAEGMGLGPPELSGSAS----------PSRYHGPARWMPPRWA--------Q 201
HFL R WTW + + + + S + G + P +
Sbjct: 127 HFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYS 186
Query: 202 GAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVE 261
E+ E HR+I+SWF D P A FGLH+L+E G+ SGKKAGDWYGP++VAHILRKAVE
Sbjct: 187 DDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVE 246
Query: 262 SCS--DVTRLVVYVSQDCTVYKADVA--RLVARPDPTAEWKSVVILVPVRLGGETLNPVY 317
D+ + +YV+QDCTVY +DV + + A+ K+V+ILVPVRLGGE N Y
Sbjct: 247 EARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDY 306
Query: 318 VPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFH 377
+ VK +L E C+GI+GGKP+ S YF G+QDD L+Y+DPHYCQ VDVS DFPLE+FH
Sbjct: 307 LEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFH 366
Query: 378 CTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQD 437
C SP+KM+F KMDPSCT+GFY + ++F+ E+T++L SS E+YP+FT GH++D
Sbjct: 367 CPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSS-KEKYPLFTFVNGHSRD 425
Query: 438 HSL-------DDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL 474
+ +DL S+ + L KR S+E+FV L
Sbjct: 426 YDFTSTTTNEEDLFSEDEKKQL-----------KRFSTEEFVLL 458
>gi|30410844 APG4 autophagy 4 homolog C isoform 7 [Homo sapiens]
Length = 458
Score = 409 bits (1052), Expect = e-114
Identities = 212/464 (45%), Positives = 289/464 (62%), Gaps = 61/464 (13%)
Query: 60 DEVDKFKAKFLTAWNNVKYGWVVKSRTSFSKISSIHLCGRRYRFEGE------------- 106
DEVDK K KF++AWNN+KY WV+K++T FS+ S + L G+ Y F+ E
Sbjct: 7 DEVDKLKTKFISAWNNMKYSWVLKTKTYFSRNSPVLLLGKCYHFKYEDEDKTLPAESGCT 66
Query: 107 -------GDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLL 159
G+++ F++DF+SR+WLTYR +FP + G LT+DCGWGC LR+GQM+LAQGL+L
Sbjct: 67 IEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEGSALTTDCGWGCTLRTGQMLLAQGLIL 126
Query: 160 HFLPRDWTWAEGMGLGPPELSGSAS----------PSRYHGPARWMPPRWA--------Q 201
HFL R WTW + + + + S + G + P +
Sbjct: 127 HFLGRAWTWPDALNIENSDSESWTSHTVKKFTASFEASLSGEREFKTPTISLKETIGKYS 186
Query: 202 GAPELEQERRHRQIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVE 261
E+ E HR+I+SWF D P A FGLH+L+E G+ SGKKAGDWYGP++VAHILRKAVE
Sbjct: 187 DDHEMRNEVYHRKIISWFGDSPLALFGLHQLIEYGKKSGKKAGDWYGPAVVAHILRKAVE 246
Query: 262 SCS--DVTRLVVYVSQDCTVYKADVA--RLVARPDPTAEWKSVVILVPVRLGGETLNPVY 317
D+ + +YV+QDCTVY +DV + + A+ K+V+ILVPVRLGGE N Y
Sbjct: 247 EARHPDLQGITIYVAQDCTVYNSDVIDKQSASMTSDNADDKAVIILVPVRLGGERTNTDY 306
Query: 318 VPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQADFPLESFH 377
+ VK +L E C+GI+GGKP+ S YF G+QDD L+Y+DPHYCQ VDVS DFPLE+FH
Sbjct: 307 LEFVKGILSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIKDFPLETFH 366
Query: 378 CTSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGHAQD 437
C SP+KM+F KMDPSCT+GFY + ++F+ E+T++L SS E+YP+FT GH++D
Sbjct: 367 CPSPKKMSFRKMDPSCTIGFYCRNVQDFKRASEEITKMLKFSS-KEKYPLFTFVNGHSRD 425
Query: 438 HSL-------DDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL 474
+ +DL S+ + L KR S+E+FV L
Sbjct: 426 YDFTSTTTNEEDLFSEDEKKQL-----------KRFSTEEFVLL 458
>gi|30795252 autophagy-related cysteine endopeptidase 2 isoform a
[Homo sapiens]
Length = 398
Score = 197 bits (501), Expect = 2e-50
Identities = 114/347 (32%), Positives = 171/347 (49%), Gaps = 66/347 (19%)
Query: 115 DFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGL 174
D +RLW TYRR F P+ G +SD GWGCMLR GQMMLAQ L+ L RDW+W +
Sbjct: 48 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEK---- 103
Query: 175 GPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVE 234
+ EQ + +++I+ F D + +H++ +
Sbjct: 104 ------------------------------QKEQPKEYQRILQCFLDRKDCCYSIHQMAQ 133
Query: 235 LGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVA----- 289
+G GK G+W+GP+ VA +L+K + + L VYVS D TV D+ ++
Sbjct: 134 MGVGEGKSIGEWFGPNTVAQVLKK-LALFDEWNSLAVYVSMDNTVVIEDIKKMCRVLPLS 192
Query: 290 ------RPDPT--------------AEWKSVVILVPVRLGGETLNPVYVPCVKELLRCEL 329
RP + + WK ++++VP+RLG +NPVYV KE +
Sbjct: 193 ADTAGDRPPDSLTASNQSKGTSAYCSAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQ 252
Query: 330 CLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDVSQ-ADFPLESFHC-TSPRKMAFA 387
LG +GGKP ++ YFIG+ D L++LDPH Q VD + ++FHC SP++M
Sbjct: 253 SLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNIL 312
Query: 388 KMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATERYPMFTLAEGH 434
+DPS +GF+ + K+F+ CS ++ E MF L + H
Sbjct: 313 NLDPSVALGFFCKEEKDFDNWCS----LVQKEILKENLRMFELVQKH 355
>gi|47132611 APG4 autophagy 4 homolog B isoform a [Homo sapiens]
Length = 393
Score = 192 bits (489), Expect = 4e-49
Identities = 124/410 (30%), Positives = 181/410 (44%), Gaps = 73/410 (17%)
Query: 94 IHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMML 153
+ + GR+Y E D D SRLW TYR++FP + G TSD GWGCMLR GQM+
Sbjct: 26 VWILGRKYSIFTEKD--EILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIF 83
Query: 154 AQGLLLHFLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHR 213
AQ L+ L RDW W + P Y
Sbjct: 84 AQALVCRHLGRDWRWTQR----------KRQPDSYFS----------------------- 110
Query: 214 QIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYV 273
+++ F D + + +H++ ++G GK G WYGP+ VA +L+K + + L V++
Sbjct: 111 -VLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKK-LAVFDTWSSLAVHI 168
Query: 274 SQDCTVYKADVARLVARPDPTA---------------------------EWKSVVILVPV 306
+ D TV ++ RL P A W+ +V+L+P+
Sbjct: 169 AMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPL 228
Query: 307 RLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDV 366
RLG +N YV +K LG++GGKP + YFIGY + L+YLDPH QP V+
Sbjct: 229 RLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEP 288
Query: 367 SQADF-PLESFHCTSPR-KMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATER 424
+ F P ESFHC P +M+ A++DPS VGF+ +F C ++ ++ A
Sbjct: 289 TDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPM 348
Query: 425 YPMFTLAEGHAQDHSLDDLCSQLAQPTLRLPRTGRLLRAKRPSSEDFVFL 474
+ + L H C + +L RL R EDF L
Sbjct: 349 FELVELQPSHL-------ACPDVLNLSLDSSDVERLERFFDSEDEDFEIL 391
>gi|30410798 APG4 autophagy 4 homolog B isoform b [Homo sapiens]
Length = 380
Score = 192 bits (488), Expect = 6e-49
Identities = 118/368 (32%), Positives = 171/368 (46%), Gaps = 69/368 (18%)
Query: 94 IHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMML 153
+ + GR+Y E D D SRLW TYR++FP + G TSD GWGCMLR GQM+
Sbjct: 26 VWILGRKYSIFTEKD--EILSDVASRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIF 83
Query: 154 AQGLLLHFLPRDWTWAEGMGLGPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHR 213
AQ L+ L RDW W + P Y
Sbjct: 84 AQALVCRHLGRDWRWTQR----------KRQPDSYFS----------------------- 110
Query: 214 QIVSWFADHPRAPFGLHRLVELGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYV 273
+++ F D + + +H++ ++G GK G WYGP+ VA +L+K + + L V++
Sbjct: 111 -VLNAFIDRKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKK-LAVFDTWSSLAVHI 168
Query: 274 SQDCTVYKADVARLVARPDPTA---------------------------EWKSVVILVPV 306
+ D TV ++ RL P A W+ +V+L+P+
Sbjct: 169 AMDNTVVMEEIRRLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPL 228
Query: 307 RLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLYLDPHYCQPTVDV 366
RLG +N YV +K LG++GGKP + YFIGY + L+YLDPH QP V+
Sbjct: 229 RLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEP 288
Query: 367 SQADF-PLESFHCTSPR-KMAFAKMDPSCTVGFYAGDRKEFETLCSELTRVLSSSSATER 424
+ F P ESFHC P +M+ A++DPS VGF+ +F C ++ ++ A
Sbjct: 289 TDGCFIPDESFHCQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGA--- 345
Query: 425 YPMFTLAE 432
PMF L E
Sbjct: 346 LPMFELVE 353
>gi|30795248 autophagy-related cysteine endopeptidase 2 isoform b
[Homo sapiens]
Length = 336
Score = 142 bits (359), Expect = 5e-34
Identities = 96/322 (29%), Positives = 142/322 (44%), Gaps = 78/322 (24%)
Query: 115 DFVSRLWLTYRRDFPPLPGGCLTSDCGWGCMLRSGQMMLAQGLLLHFLPRDWTWAEGMGL 174
D +RLW TYRR F P+ G +SD GWGCMLR GQMMLAQ L+ L RDW+W +
Sbjct: 48 DISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWSWEK---- 103
Query: 175 GPPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIVSWFADHPRAPFGLHRLVE 234
+ EQ + +++I+ F D + +H++ +
Sbjct: 104 ------------------------------QKEQPKEYQRILQCFLDRKDCCYSIHQMAQ 133
Query: 235 LGQSSGKKAGDWYGPSLVAHILRKAVESCSDVTRLVVYVSQDCTVYKADVARLVARPDPT 294
+G GK G+W+GP+ VA +L+K + + L VYVS D TV D+
Sbjct: 134 MGVGEGKSIGEWFGPNTVAQVLKK-LALFDEWNSLAVYVSMDNTVVIEDI---------- 182
Query: 295 AEWKSVVILVPVRLGGETLNPVYVPCVKELLRCELCLGIMGGKPRHSLYFIGYQDDFLLY 354
K + ++P L G +P SL Q D L++
Sbjct: 183 ---KKMCRVLP-----------------------LSADTAGDRPPDSL-TASNQSDELIF 215
Query: 355 LDPHYCQPTVDVSQ-ADFPLESFHC-TSPRKMAFAKMDPSCTVGFYAGDRKEFETLCSEL 412
LDPH Q VD + ++FHC SP++M +DPS +GF+ + K+F+ CS
Sbjct: 216 LDPHTTQTFVDTEENGTVNDQTFHCLQSPQRMNILNLDPSVALGFFCKEEKDFDNWCS-- 273
Query: 413 TRVLSSSSATERYPMFTLAEGH 434
++ E MF L + H
Sbjct: 274 --LVQKEILKENLRMFELVQKH 293
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
Length = 2161
Score = 36.2 bits (82), Expect = 0.067
Identities = 24/55 (43%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 5 SPAAAQYRSSS----PEDARRRPEARRPRG--PRGPDPNGLGPSGASGPALGSPG 53
SP A+ RS S PEDA+R+P R PR G G SG G +LGS G
Sbjct: 491 SPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRG 545
Score = 29.6 bits (65), Expect = 6.2
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 3/52 (5%)
Query: 11 YRSSSPEDARRRPEARR---PRGPRGPDPNGLGPSGASGPALGSPGAGPSEP 59
+RS++PE+ R P R PR P +G GP GP + P S P
Sbjct: 1477 WRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVP 1528
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 6 PAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALG--SPGAGPSE 58
P AA R SPE AR P P PR P P P A GP G SPGA S+
Sbjct: 81 PPAAPRRRGSPERARPPPPPPPPAPPR-PPPAAPSPPAAPGPRGGGASPGARRSD 134
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/55 (45%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 6 PAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALG--SPGAGPSE 58
P AA R SPE AR P P PR P P P A GP G SPGA S+
Sbjct: 81 PPAAPRRRGSPERARPPPPPPPPAPPR-PPPAAPSPPAAPGPRGGGASPGARRSD 134
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 34.7 bits (78), Expect = 0.19
Identities = 29/74 (39%), Positives = 34/74 (45%), Gaps = 19/74 (25%)
Query: 32 RGPDPNGLGPSGASGPALGSPGAGPSEPDEVDKFKAKFLTAWNNVKYG-WVVKSRTSFSK 90
R P P+ L PS ASGP G+P GP P F+ K L W+ G W
Sbjct: 1651 RSPSPSPL-PSPASGPGPGAP--GPRRP-----FQQKPLQLWSKFDVGDW---------- 1692
Query: 91 ISSIHLCGRRYRFE 104
+ SIHL R RFE
Sbjct: 1693 LESIHLGEHRDRFE 1706
>gi|41152072 zinc finger, DHHC domain containing 5 [Homo sapiens]
Length = 715
Score = 34.3 bits (77), Expect = 0.25
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 13 SSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEP 59
SSS +D++R P + P G R P P G G +GSP GP+ P
Sbjct: 584 SSSSDDSKRSPLGKTPLG-RPAVPRFGKPDGLRGRGVGSPEPGPTAP 629
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 33.9 bits (76), Expect = 0.33
Identities = 19/38 (50%), Positives = 21/38 (55%), Gaps = 3/38 (7%)
Query: 23 PEARRPRGPRGP--DPNGLGPSGASGPALGSPGAGPSE 58
P AR PRGP GP +P GP GA G G PG P +
Sbjct: 648 PGARGPRGPPGPYGNPGLPGPPGAKGQK-GDPGLSPGK 684
Score = 33.1 bits (74), Expect = 0.56
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 14 SSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGA 54
+ PE + +P AR GPRG LGP G GP +G PGA
Sbjct: 921 NGPEGMKGKPGARGLPGPRGQ----LGPEGDEGP-MGPPGA 956
Score = 31.6 bits (70), Expect = 1.6
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 14 SSPEDARRRPEARRPRGPRGP--DPNGLGPSGASGPALGSPG 53
S P + P P+GP+GP P +GP G G A+G PG
Sbjct: 1119 SGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPG-AVGEPG 1159
>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
Length = 684
Score = 33.5 bits (75), Expect = 0.43
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 7/68 (10%)
Query: 4 VSPAAAQYRSSSPEDARRRPEARRPRGPRGP-----DPNGLGPSGASGPA--LGSPGAGP 56
++ AA R + RP P GP GP P GP G GP LG PG
Sbjct: 537 IAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRG 596
Query: 57 SEPDEVDK 64
++ D DK
Sbjct: 597 NQGDRGDK 604
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 33.1 bits (74), Expect = 0.56
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 6 PAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPG 53
PA SS+ + +RRP PR RG P SG S P GSPG
Sbjct: 494 PAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSP--GSPG 539
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 33.1 bits (74), Expect = 0.56
Identities = 24/91 (26%), Positives = 31/91 (34%), Gaps = 2/91 (2%)
Query: 142 WGCMLRSGQMMLAQGLLLHFLPRDW--TWAEGMGLGPPELSGSASPSRYHGPARWMPPRW 199
W C L++G + G L R W +W +G S P PA P
Sbjct: 120 WQCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSSRHLPGSASSPALLQPLAG 179
Query: 200 AQGAPELEQERRHRQIVSWFADHPRAPFGLH 230
A G + +R SW H R G H
Sbjct: 180 AVGQLWSQHQRPSATCASWSGFHYRTFDGRH 210
>gi|111955326 MLX interacting protein [Homo sapiens]
Length = 919
Score = 32.7 bits (73), Expect = 0.74
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 176 PPELSGSASPSRYHGPARWMPPRWAQGAPELEQERRHRQIV 216
PP SG+A+P+R H A PPR P E+ R +QI+
Sbjct: 40 PPPASGAATPARAHASAAPPPPR---AGPGREEPPRRQQII 77
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 32.3 bits (72), Expect = 0.96
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 7/58 (12%)
Query: 7 AAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGA---GPSEPDE 61
+AA + + P++A P A PR P P+P G PS +LG P GP+EP+E
Sbjct: 1167 SAAPDQHTHPKEAATDPPA--PRTP--PEPPGSPPSSPPPASLGRPEGEEEGPAEPEE 1220
>gi|223278377 antimicrobial peptide RY2G5 [Homo sapiens]
Length = 614
Score = 32.3 bits (72), Expect = 0.96
Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 77 KYGWVVKSRTSFSKISSIHLCGRRYRFEGEGDIQRFQRDFVSRLWLTYRRDFPP--LPGG 134
+YG +++S S + + + G + R++ V RL +RR+ P +P G
Sbjct: 104 RYGEILESEGSIRDLRNSGYRSAENAYGGHRGLGRYRAAPVGRL---HRRELQPGEIPPG 160
Query: 135 CLTSDCGWGCMLRSGQMMLAQGLL 158
T G G +L +G M+ A G+L
Sbjct: 161 VATGAVGPGGLLGTGGMLAADGIL 184
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 32.3 bits (72), Expect = 0.96
Identities = 17/32 (53%), Positives = 21/32 (65%), Gaps = 6/32 (18%)
Query: 28 PRGPRGP-----DPNGLGPSGASGPALGSPGA 54
PRG GP +P GP+GA+GPA G+PGA
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPA-GNPGA 390
Score = 31.2 bits (69), Expect = 2.1
Identities = 23/56 (41%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 2 NSVSPAAAQYRSSS-PEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGP 56
N +P A R S+ P A P A GP GP N GP G GPA G GP
Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNA-GPPGPPGPAGKEGGKGP 909
Score = 30.4 bits (67), Expect = 3.7
Identities = 18/38 (47%), Positives = 21/38 (55%), Gaps = 5/38 (13%)
Query: 23 PEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEPD 60
P AR P GP+GP GP G G + G PGA S+ D
Sbjct: 412 PGARGPSGPQGPG----GPPGPKGNS-GEPGAPGSKGD 444
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/30 (56%), Positives = 19/30 (63%), Gaps = 4/30 (13%)
Query: 29 RGPRGP--DPNGLGPSGASGPA--LGSPGA 54
+GP GP P GPSGASGPA G PG+
Sbjct: 1117 QGPPGPPGSPGEQGPSGASGPAGPRGPPGS 1146
Score = 29.3 bits (64), Expect = 8.1
Identities = 18/35 (51%), Positives = 19/35 (54%), Gaps = 4/35 (11%)
Query: 28 PRGPRGP--DPNGLGPSGASGPALGSPG-AGPSEP 59
P GP GP G GP G +GPA G PG GP P
Sbjct: 894 PPGPPGPAGKEGGKGPRGETGPA-GRPGEVGPPGP 927
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 32.3 bits (72), Expect = 0.96
Identities = 22/40 (55%), Positives = 24/40 (60%), Gaps = 4/40 (10%)
Query: 20 RRRPEARRPRGPRG--PDPNGLGPSGASGPALGSPGA-GP 56
R P A+ +GPRG P GP GASGPA G PGA GP
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPA-GPPGAQGP 745
Score = 29.6 bits (65), Expect = 6.2
Identities = 21/44 (47%), Positives = 23/44 (52%), Gaps = 10/44 (22%)
Query: 23 PEARRPRGPRGPDPNGLGPSGASGPA-----LGSPGA-GPSEPD 60
P A RGP GP +GP G +GPA GSPGA GP D
Sbjct: 1010 PGASGDRGPPGP----VGPPGLTGPAGEPGREGSPGADGPPGRD 1049
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 32.3 bits (72), Expect = 0.96
Identities = 22/40 (55%), Positives = 24/40 (60%), Gaps = 4/40 (10%)
Query: 20 RRRPEARRPRGPRG--PDPNGLGPSGASGPALGSPGA-GP 56
R P A+ +GPRG P GP GASGPA G PGA GP
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPA-GPPGAQGP 676
Score = 29.6 bits (65), Expect = 6.2
Identities = 21/44 (47%), Positives = 23/44 (52%), Gaps = 10/44 (22%)
Query: 23 PEARRPRGPRGPDPNGLGPSGASGPA-----LGSPGA-GPSEPD 60
P A RGP GP +GP G +GPA GSPGA GP D
Sbjct: 941 PGASGDRGPPGP----VGPPGLTGPAGEPGREGSPGADGPPGRD 980
>gi|239756047 PREDICTED: heparan sulfate 6-O-sulfotransferase 3
[Homo sapiens]
Length = 471
Score = 32.3 bits (72), Expect = 0.96
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
Query: 6 PAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGP-----ALGSPGAGPSEPD 60
P A+ + PE+ RRP+ P PRGP GP GA+ P G P G E +
Sbjct: 52 PGPARRAQAPPEEWERRPQL--PPPPRGPPE---GPRGAAAPEEEDEEPGDPREGEEEEE 106
Query: 61 E 61
E
Sbjct: 107 E 107
>gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]
Length = 306
Score = 32.3 bits (72), Expect = 0.96
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 PEDARRRPEARRPRGPRGPDPNGLGPSGAS-----GPALGSPGAGPSEPDEVDKFKAK 68
PE P R P G GP P P G G PG G E E++ KA+
Sbjct: 68 PEPEEEPPRPRAPPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIEDPELEAIKAR 125
>gi|45580707 heparan sulfate 6-O-sulfotransferase 3 [Homo sapiens]
Length = 471
Score = 32.3 bits (72), Expect = 0.96
Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
Query: 6 PAAAQYRSSSPEDARRRPEARRPRGPRGPDPNGLGPSGASGP-----ALGSPGAGPSEPD 60
P A+ + PE+ RRP+ P PRGP GP GA+ P G P G E +
Sbjct: 52 PGPARRAQAPPEEWERRPQL--PPPPRGPPE---GPRGAAAPEEEDEEPGDPREGEEEEE 106
Query: 61 E 61
E
Sbjct: 107 E 107
>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 32.3 bits (72), Expect = 0.96
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
Query: 22 RPEARRPRGPRGPD--PNGLGPSGASGPALGSPGAG--PSEP 59
+P P+G RG P LGP G GP +G+PG G P EP
Sbjct: 352 KPGFPGPKGDRGMGGVPGALGPRGEKGP-IGAPGIGGPPGEP 392
>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 32.3 bits (72), Expect = 0.96
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 5/42 (11%)
Query: 22 RPEARRPRGPRGPD--PNGLGPSGASGPALGSPGAG--PSEP 59
+P P+G RG P LGP G GP +G+PG G P EP
Sbjct: 352 KPGFPGPKGDRGMGGVPGALGPRGEKGP-IGAPGIGGPPGEP 392
>gi|118498339 EMI domain containing 2 [Homo sapiens]
Length = 439
Score = 32.3 bits (72), Expect = 0.96
Identities = 17/31 (54%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 23 PEARRPRGPRGPDPNGLGPSGASGPALGSPG 53
P RRP GP GP P GP G +GP GS G
Sbjct: 190 PRQRRPTGPAGP-PGQTGPPGPAGPP-GSKG 218
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 32.3 bits (72), Expect = 0.96
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 4/44 (9%)
Query: 16 PEDARRRPEARRPRGPRGPDPNGLGPSGASGPALGSPGAGPSEP 59
P+ +R P P GP+GP GP G+SGP GP P
Sbjct: 674 PQGMQRHPGPHGPLGPQGPP----GPQGSSGPQGHMGPQGPPGP 713
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Query: 14 SSPEDARRRPEARRPRGPRGPD-PNGL----GPSGASGPA--LGSPGAGPSEPD 60
+ P A +P A+ RG +GP NG+ GP GA+GPA G PG S D
Sbjct: 726 AGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD 779
Score = 30.8 bits (68), Expect = 2.8
Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 7/41 (17%)
Query: 23 PEARRPRGPRGPDPNGLGPSGASGPA--LGSPG-AGPSEPD 60
P PRG RGP G SGA+GP +GS G +GP PD
Sbjct: 582 PGPAGPRGERGPP----GESGAAGPTGPIGSRGPSGPPGPD 618
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,645,235
Number of Sequences: 37866
Number of extensions: 1229760
Number of successful extensions: 6066
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 5706
Number of HSP's gapped (non-prelim): 438
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.