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Search of human proteins with 27886665
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27886665 potassium voltage-gated channel, subfamily H,
member 7 isoform 2 [Homo sapiens]
(732 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27886665 potassium voltage-gated channel, subfamily H, member... 1478 0.0
gi|27886653 potassium voltage-gated channel, subfamily H, member... 1434 0.0
gi|26051271 voltage-gated potassium channel, subfamily H, member... 930 0.0
gi|4557729 voltage-gated potassium channel, subfamily H, member ... 930 0.0
gi|13540549 potassium voltage-gated channel, subfamily H, member... 674 0.0
gi|26051273 voltage-gated potassium channel, subfamily H, member... 592 e-169
gi|27886651 potassium voltage-gated channel, subfamily H, member... 479 e-135
gi|27886667 potassium voltage-gated channel, subfamily H, member... 350 3e-96
gi|6912446 potassium voltage-gated channel, subfamily H, member ... 330 3e-90
gi|22024390 potassium voltage-gated channel, subfamily H, member... 327 2e-89
gi|27886648 potassium voltage-gated channel, subfamily H, member... 327 2e-89
gi|27886646 potassium voltage-gated channel, subfamily H, member... 327 2e-89
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 325 7e-89
gi|27437001 potassium voltage-gated channel, subfamily H, member... 316 4e-86
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re... 307 3e-83
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 136 8e-32
gi|116325989 hyperpolarization activated cyclic nucleotide-gated... 133 5e-31
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 132 1e-30
gi|38327037 hyperpolarization activated cyclic nucleotide-gated ... 119 8e-27
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [... 103 7e-22
gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [H... 103 7e-22
gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2 [... 93 8e-19
gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Ho... 93 8e-19
gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens] 88 2e-17
gi|82617546 cyclic nucleotide gated channel alpha 4 [Homo sapiens] 87 4e-17
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 55 2e-07
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 43 0.001
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 43 0.001
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 40 0.006
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 40 0.010
>gi|27886665 potassium voltage-gated channel, subfamily H, member 7
isoform 2 [Homo sapiens]
Length = 732
Score = 1478 bits (3826), Expect = 0.0
Identities = 732/732 (100%), Positives = 732/732 (100%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
Sbjct: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
Sbjct: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Query: 121 VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP 180
VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP
Sbjct: 121 VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP 180
Query: 181 DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP 240
DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP
Sbjct: 181 DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP 240
Query: 241 KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEGPF 300
KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEGPF
Sbjct: 241 KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEGPF 300
Query: 301 NHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRT 360
NHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRT
Sbjct: 301 NHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRT 360
Query: 361 HNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPY 420
HNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPY
Sbjct: 361 HNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPY 420
Query: 421 SAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAK 480
SAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAK
Sbjct: 421 SAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAK 480
Query: 481 IAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEY 540
IAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEY
Sbjct: 481 IAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEY 540
Query: 541 GAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSG 600
GAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSG
Sbjct: 541 GAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSG 600
Query: 601 PSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQ 660
PSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQ
Sbjct: 601 PSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQ 660
Query: 661 RLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSVFQNE 720
RLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSVFQNE
Sbjct: 661 RLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSVFQNE 720
Query: 721 SAAGIIVIAKME 732
SAAGIIVIAKME
Sbjct: 721 SAAGIIVIAKME 732
>gi|27886653 potassium voltage-gated channel, subfamily H, member 7
isoform 1 [Homo sapiens]
Length = 1196
Score = 1434 bits (3711), Expect = 0.0
Identities = 712/719 (99%), Positives = 712/719 (99%), Gaps = 7/719 (0%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
Sbjct: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
Sbjct: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Query: 121 VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP 180
VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP
Sbjct: 121 VAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSLPQEDP 180
Query: 181 DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP 240
DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP
Sbjct: 181 DVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSP 240
Query: 241 KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASE--- 297
KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASE
Sbjct: 241 KRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEDNG 300
Query: 298 ----GPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIA 353
GPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIA
Sbjct: 301 RNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIA 360
Query: 354 PKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIY 413
PKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIY
Sbjct: 361 PKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIY 420
Query: 414 TAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEE 473
TAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEE
Sbjct: 421 TAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEE 480
Query: 474 VVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARK 533
VVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARK
Sbjct: 481 VVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARK 540
Query: 534 LDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYN 593
LDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYN
Sbjct: 541 LDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYN 600
Query: 594 DSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFG 653
DSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFG
Sbjct: 601 DSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFG 660
Query: 654 NVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 712
NVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV
Sbjct: 661 NVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 719
>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
isoform b [Homo sapiens]
Length = 888
Score = 930 bits (2403), Expect = 0.0
Identities = 490/730 (67%), Positives = 564/730 (77%), Gaps = 32/730 (4%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNTFL TIIRKFEGQ++KFIIANARV+NCA+IYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Q+PCTCDFLHGP T+R AQIAQALLG+EERKVE+ +Y K+GS F+C ++PVKN++G
Sbjct: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Query: 121 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL 175
+MFI+NFE V + + +P R P + K F K P L LT R+ S+
Sbjct: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
Query: 176 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC 225
P VV+D + S +S+A+ + A++ +AL+ P
Sbjct: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG-- 238
Query: 226 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G 283
SP + G L P + L PD SS L+ +RSRES S+RRASS DIE G
Sbjct: 239 SPPRSAPGQL----PSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG 294
Query: 284 VHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSS 343
V P RHAS G + ++S LL STSDS+L +Y TI+KIPQ+TLNF ++K + +S
Sbjct: 295 VLPPP---PRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLAS 351
Query: 344 PPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVW 403
P +SD+ IIAPK+K+RTHNVTEKVTQVLSLGADVLPEYKLQ PRI+++TILHYSPFKAVW
Sbjct: 352 P-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVW 410
Query: 404 DWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDILIN 462
DWLILLLVIYTA+FTPYSAAFLL + EE ECGY+C PL VVDLIVDIMFI+DILIN
Sbjct: 411 DWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILIN 470
Query: 463 FRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTA 522
FRTTYVN NEEVVS P +IA+HYFKGWFLIDMVAAIPFDLLIFGSGS+E LIGLLKTA
Sbjct: 471 FRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTA 527
Query: 523 RLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLD 582
RLLRLVRVARKLDRYSEYGAAVL LLMC FALIAHWLACIWYAIGN+E+P++ +IGWL
Sbjct: 528 RLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLH 587
Query: 583 SLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
+LG QIGK YN S GPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
Sbjct: 588 NLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 646
Query: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
IGSLMYASIFGNVSAIIQRLYSGTARYH QMLRV+EFIRFHQIPNPLRQRLEEYFQHAW+
Sbjct: 647 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS 706
Query: 703 YTNGIDMNMV 712
YTNGIDMN V
Sbjct: 707 YTNGIDMNAV 716
>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
isoform a [Homo sapiens]
Length = 1159
Score = 930 bits (2403), Expect = 0.0
Identities = 490/730 (67%), Positives = 564/730 (77%), Gaps = 32/730 (4%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNTFL TIIRKFEGQ++KFIIANARV+NCA+IYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Q+PCTCDFLHGP T+R AQIAQALLG+EERKVE+ +Y K+GS F+C ++PVKN++G
Sbjct: 61 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG 120
Query: 121 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL 175
+MFI+NFE V + + +P R P + K F K P L LT R+ S+
Sbjct: 121 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV 180
Query: 176 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC 225
P VV+D + S +S+A+ + A++ +AL+ P
Sbjct: 181 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG-- 238
Query: 226 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G 283
SP + G L P + L PD SS L+ +RSRES S+RRASS DIE G
Sbjct: 239 SPPRSAPGQL----PSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG 294
Query: 284 VHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSS 343
V P RHAS G + ++S LL STSDS+L +Y TI+KIPQ+TLNF ++K + +S
Sbjct: 295 VLPPP---PRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLAS 351
Query: 344 PPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVW 403
P +SD+ IIAPK+K+RTHNVTEKVTQVLSLGADVLPEYKLQ PRI+++TILHYSPFKAVW
Sbjct: 352 P-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVW 410
Query: 404 DWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDILIN 462
DWLILLLVIYTA+FTPYSAAFLL + EE ECGY+C PL VVDLIVDIMFI+DILIN
Sbjct: 411 DWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILIN 470
Query: 463 FRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTA 522
FRTTYVN NEEVVS P +IA+HYFKGWFLIDMVAAIPFDLLIFGSGS+E LIGLLKTA
Sbjct: 471 FRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTA 527
Query: 523 RLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLD 582
RLLRLVRVARKLDRYSEYGAAVL LLMC FALIAHWLACIWYAIGN+E+P++ +IGWL
Sbjct: 528 RLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLH 587
Query: 583 SLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
+LG QIGK YN S GPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
Sbjct: 588 NLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 646
Query: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
IGSLMYASIFGNVSAIIQRLYSGTARYH QMLRV+EFIRFHQIPNPLRQRLEEYFQHAW+
Sbjct: 647 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS 706
Query: 703 YTNGIDMNMV 712
YTNGIDMN V
Sbjct: 707 YTNGIDMNAV 716
>gi|13540549 potassium voltage-gated channel, subfamily H, member 6
isoform 1 [Homo sapiens]
Length = 994
Score = 674 bits (1738), Expect = 0.0
Identities = 331/395 (83%), Positives = 358/395 (90%)
Query: 318 KYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADV 377
KY TI++IPQ TLNF E EK SS + + I KV +RT NVTEKVTQVLSLGADV
Sbjct: 174 KYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADV 233
Query: 378 LPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRREC 437
LPEYKLQ PRI+++TILHYSPFKAVWDWLILLLVIYTA+FTPYSAAFLL+D++E +R C
Sbjct: 234 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGAC 293
Query: 438 GYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAA 497
Y+CSPL VVDLIVDIMF++DI+INFRTTYVN N+EVVS P +IA+HYFKGWFLIDMVAA
Sbjct: 294 SYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAA 353
Query: 498 IPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAH 557
IPFDLLIF +GSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVL LLMC FALIAH
Sbjct: 354 IPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAH 413
Query: 558 WLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSS 617
WLACIWYAIGNVERPYL KIGWLDSLG Q+GKRYN SD +SGPS++DKYVTALYFTFSS
Sbjct: 414 WLACIWYAIGNVERPYLEHKIGWLDSLGVQLGKRYNGSDPASGPSVQDKYVTALYFTFSS 473
Query: 618 LTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVK 677
LTSVGFGNVSPNTNSEK+FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYH QMLRVK
Sbjct: 474 LTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVK 533
Query: 678 EFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 712
EFIRFHQIPNPLRQRLEEYFQHAW+YTNGIDMN V
Sbjct: 534 EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAV 568
Score = 194 bits (492), Expect = 3e-49
Identities = 85/130 (65%), Positives = 111/130 (85%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNT+L TIIRKFEGQ++KF+IANA+++NCAIIYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Q+PCTCDFL GP T ++++AQALLG+EE KV++ YY K+ S+F C ++PVKN++G
Sbjct: 61 QQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDG 120
Query: 121 VAMMFIINFE 130
+MFI+NFE
Sbjct: 121 AVIMFILNFE 130
>gi|26051273 voltage-gated potassium channel, subfamily H, member 2
isoform c [Homo sapiens]
Length = 819
Score = 592 bits (1527), Expect = e-169
Identities = 296/345 (85%), Positives = 315/345 (91%), Gaps = 5/345 (1%)
Query: 369 QVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLND 428
+VLSLGADVLPEYKLQ PRI+++TILHYSPFKAVWDWLILLLVIYTA+FTPYSAAFLL +
Sbjct: 36 EVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKE 95
Query: 429 REE-QKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFK 487
EE ECGY+C PL VVDLIVDIMFI+DILINFRTTYVN NEEVVS P +IA+HYFK
Sbjct: 96 TEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFK 155
Query: 488 GWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLML 547
GWFLIDMVAAIPFDLLIFGSGS+E LIGLLKTARLLRLVRVARKLDRYSEYGAAVL L
Sbjct: 156 GWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL 212
Query: 548 LMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKY 607
LMC FALIAHWLACIWYAIGN+E+P++ +IGWL +LG QIGK YN S GPSIKDKY
Sbjct: 213 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKY 271
Query: 608 VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA 667
VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA
Sbjct: 272 VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA 331
Query: 668 RYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 712
RYH QMLRV+EFIRFHQIPNPLRQRLEEYFQHAW+YTNGIDMN V
Sbjct: 332 RYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAV 376
>gi|27886651 potassium voltage-gated channel, subfamily H, member 6
isoform 2 [Homo sapiens]
Length = 905
Score = 479 bits (1233), Expect = e-135
Identities = 260/395 (65%), Positives = 289/395 (73%), Gaps = 53/395 (13%)
Query: 318 KYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADV 377
KY TI++IPQ TLNF E EK SS + + I KV +RT NVTEKVTQVLSLGADV
Sbjct: 174 KYRTISQIPQFTLNFVEFNLEKHRSSSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADV 233
Query: 378 LPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRREC 437
LPEYKLQ PRI+++TILHYSPFKAVWDWLILLLVIYTA+FTPYSAAFLL+D++E +R C
Sbjct: 234 LPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESRRGAC 293
Query: 438 GYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAA 497
Y+CSPL VVDLIVDIMF++DI+INFRTTYVN N+EVVS P +IA+HYFKGWFLIDMVAA
Sbjct: 294 SYTCSPLTVVDLIVDIMFVVDIVINFRTTYVNTNDEVVSHPRRIAVHYFKGWFLIDMVAA 353
Query: 498 IPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAH 557
IPFDLLIF +GSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVL LLMC FALIAH
Sbjct: 354 IPFDLLIFRTGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAH 413
Query: 558 WLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSS 617
WLACI L S+G G +++S SI + +L +
Sbjct: 414 WLACICS----------------LTSVG--FGNVSPNTNSEKVFSICVMLIGSLMYASI- 454
Query: 618 LTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVK 677
FGNV SAIIQRLYSGTARYH QMLRVK
Sbjct: 455 -----FGNV-----------------------------SAIIQRLYSGTARYHTQMLRVK 480
Query: 678 EFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 712
EFIRFHQIPNPLRQRLEEYFQHAW+YTNGIDMN V
Sbjct: 481 EFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAV 515
Score = 194 bits (492), Expect = 3e-49
Identities = 85/130 (65%), Positives = 111/130 (85%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM 60
MPVRRGHVAPQNT+L TIIRKFEGQ++KF+IANA+++NCAIIYCNDGFCE+ G+SR +VM
Sbjct: 1 MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVM 60
Query: 61 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG 120
Q+PCTCDFL GP T ++++AQALLG+EE KV++ YY K+ S+F C ++PVKN++G
Sbjct: 61 QQPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDG 120
Query: 121 VAMMFIINFE 130
+MFI+NFE
Sbjct: 121 AVIMFILNFE 130
>gi|27886667 potassium voltage-gated channel, subfamily H, member 8
[Homo sapiens]
Length = 1107
Score = 350 bits (897), Expect = 3e-96
Identities = 174/348 (50%), Positives = 238/348 (68%), Gaps = 13/348 (3%)
Query: 366 KVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFL 425
K+ + + PEYK+ + +KF +LH+S FKA WDWLILL Y A+ PY+ F+
Sbjct: 187 KINNNVFVDKPAFPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFI 246
Query: 426 LNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHY 485
ND R V D+ V+I+FIIDI++NFRTTYV+++ +V+ + I IHY
Sbjct: 247 GNDDLSTTRST--------TVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHY 298
Query: 486 FKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVL 545
WF+ID++AA+PFDLL + + +L+ LLKT RLLRL+R+ +KLDRYS++ VL
Sbjct: 299 VTTWFIIDLIAALPFDLLY--AFNVTVVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVL 356
Query: 546 MLLMCIFALIAHWLACIWYAIGNVERP---YLTDKIGWLDSLGQQIGKRYNDSDSSSGPS 602
LLM +FAL+AHW+ACIWY IG +ER L ++GWL LG+++ Y +++ GPS
Sbjct: 357 TLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYGNNTLGGPS 416
Query: 603 IKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRL 662
I+ Y+ ALYFT SSLTSVGFGNVS NT++EKIFSIC MLIG+LM+A +FGNV+AIIQR+
Sbjct: 417 IRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRM 476
Query: 663 YSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMN 710
YS + YH + +K+FIR H +P L+QR+ EYFQ W+ NGID N
Sbjct: 477 YSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSN 524
Score = 143 bits (360), Expect = 6e-34
Identities = 68/143 (47%), Positives = 98/143 (68%), Gaps = 1/143 (0%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARV-QNCAIIYCNDGFCEMTGFSRPDV 59
MPV +G +APQNTFL TI +F+G + FI+ANA+V + I+YC+DGFCE+ GF+R +V
Sbjct: 1 MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEV 60
Query: 60 MQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQE 119
MQK C+C FL G ET + QI ++L E K E+ +Y KNGS F C I+P+KN++
Sbjct: 61 MQKSCSCKFLFGVETNEQLMLQIEKSLEEKTEFKGEIMFYKKNGSPFWCLLDIVPIKNEK 120
Query: 120 GVAMMFIINFEYVTDNENAATPE 142
G ++F+ +F+ +TD + TPE
Sbjct: 121 GDVVLFLASFKDITDTKVKITPE 143
>gi|6912446 potassium voltage-gated channel, subfamily H, member 4
[Homo sapiens]
Length = 1017
Score = 330 bits (846), Expect = 3e-90
Identities = 172/337 (51%), Positives = 231/337 (68%), Gaps = 15/337 (4%)
Query: 378 LPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRREC 437
+PEYK+ + ++ +LHYS KA+WD LILL Y A+ PY+ F +D R
Sbjct: 204 VPEYKVASVGGSRCLLLHYSVSKAIWDGLILLATFYVAVTVPYNVCFSGDDDTPITSRHT 263
Query: 438 GYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAA 497
S D+ V+++FI+DI++NFRTTYV+Q+ +V+S P I +HY WF ID++AA
Sbjct: 264 LVS-------DIAVEMLFILDIILNFRTTYVSQSGQVISAPRSIGLHYLATWFFIDLIAA 316
Query: 498 IPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAH 557
+PFDLL + + T+L+ LLKT RLLRL+R+ +KL+RYS+ A VL LLM +FAL+AH
Sbjct: 317 LPFDLLYIFNIT--VTSLVHLLKTVRLLRLLRLLQKLERYSQCSAVVLTLLMSVFALLAH 374
Query: 558 WLACIWYAIGNVER----PYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYF 613
W+ACIWY IG E P L D IGWL LG+++ Y + S GPS + Y+ ALYF
Sbjct: 375 WMACIWYVIGRREMEANDPLLWD-IGWLHELGKRLEVPYVNG-SVGGPSRRSAYIAALYF 432
Query: 614 TFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQM 673
T SSLTSVGFGNV NT++EKIFSIC MLIG+LM+A +FGNV+AIIQR+YS + YH +M
Sbjct: 433 TLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHAVVFGNVTAIIQRMYSRRSLYHSRM 492
Query: 674 LRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMN 710
+K+FIR H++P PL+QR+ EYFQ W +GID N
Sbjct: 493 KDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDAN 529
Score = 139 bits (349), Expect = 1e-32
Identities = 60/136 (44%), Positives = 96/136 (70%), Gaps = 1/136 (0%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANAR-VQNCAIIYCNDGFCEMTGFSRPDV 59
MPV +G +APQNTFL TI +F+G + F++ANA+ + I+YC+DGFCE+TG+ R +V
Sbjct: 1 MPVMKGLLAPQNTFLDTIATRFDGTHSNFLLANAQGTRGFPIVYCSDGFCELTGYGRTEV 60
Query: 60 MQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQE 119
MQK C+C FL+GPET + ++ +AL G +E + E+ +Y K+GS F C ++P+KN+
Sbjct: 61 MQKTCSCRFLYGPETSEPALQRLHKALEGHQEHRAEICFYRKDGSAFWCLLDMMPIKNEM 120
Query: 120 GVAMMFIINFEYVTDN 135
G ++F+ +F+ +T +
Sbjct: 121 GEVVLFLFSFKDITQS 136
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 327 bits (838), Expect = 2e-89
Identities = 167/385 (43%), Positives = 248/385 (64%), Gaps = 21/385 (5%)
Query: 352 IAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLV 411
+ P K + ++ +VL LG+D+LP+YK + P+ ILHY FK WDW+IL+L
Sbjct: 166 LTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILT 225
Query: 412 IYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQN 471
YTAI PY+ +F + K+ + V+D +VD++F++DI++NF TT+V
Sbjct: 226 FYTAIMVPYNVSF------KTKQNNIAWL-----VLDSVVDVIFLVDIVLNFHTTFVGPG 274
Query: 472 EEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDE-TTTLIGLLKTARLLRLVRV 530
EV+SDP I ++Y K WF+ID+++ +P+D++ DE ++L LK RLLRL RV
Sbjct: 275 GEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRV 334
Query: 531 ARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVER-PYLTDKI---GWLDSLGQ 586
ARKLD Y EYGAAVL+LL+C+F L+AHWLACIWY+IG+ E +T+ I WL L
Sbjct: 335 ARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLAL 394
Query: 587 QIGK--RYNDSDS--SSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
IG RYN S GPS YV++LYFT +SLT++GFGN++P T+ EK+FS+ +M+
Sbjct: 395 SIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMM 454
Query: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
+GSL+YA+IFGNV+ I Q++Y+ T RYH + V++F++ +Q+P L +R+ +Y W+
Sbjct: 455 VGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWS 514
Query: 703 YTNGIDMNMVCMSVFQNESAAGIIV 727
+ GID V +S+ + A I V
Sbjct: 515 MSKGIDTEKV-LSICPKDMRADICV 538
Score = 98.6 bits (244), Expect = 2e-20
Identities = 47/130 (36%), Positives = 75/130 (57%), Gaps = 2/130 (1%)
Query: 4 RRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKP 63
+RG VAPQNTFL I+R+ F++ NA++ + ++Y NDGFC+++G+ R DVMQK
Sbjct: 5 KRGLVAPQNTFLENIVRR--SSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKS 62
Query: 64 CTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAM 123
TC F++G T + I ++ Q E EV Y KN + I P++N+ +
Sbjct: 63 STCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVV 122
Query: 124 MFIINFEYVT 133
+F+ F+ +T
Sbjct: 123 LFLCTFKDIT 132
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 327 bits (838), Expect = 2e-89
Identities = 167/385 (43%), Positives = 248/385 (64%), Gaps = 21/385 (5%)
Query: 352 IAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLV 411
+ P K + ++ +VL LG+D+LP+YK + P+ ILHY FK WDW+IL+L
Sbjct: 108 LTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILT 167
Query: 412 IYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQN 471
YTAI PY+ +F + K+ + V+D +VD++F++DI++NF TT+V
Sbjct: 168 FYTAIMVPYNVSF------KTKQNNIAWL-----VLDSVVDVIFLVDIVLNFHTTFVGPG 216
Query: 472 EEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDE-TTTLIGLLKTARLLRLVRV 530
EV+SDP I ++Y K WF+ID+++ +P+D++ DE ++L LK RLLRL RV
Sbjct: 217 GEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRV 276
Query: 531 ARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVER-PYLTDKI---GWLDSLGQ 586
ARKLD Y EYGAAVL+LL+C+F L+AHWLACIWY+IG+ E +T+ I WL L
Sbjct: 277 ARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLAL 336
Query: 587 QIGK--RYNDSDS--SSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
IG RYN S GPS YV++LYFT +SLT++GFGN++P T+ EK+FS+ +M+
Sbjct: 337 SIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMM 396
Query: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
+GSL+YA+IFGNV+ I Q++Y+ T RYH + V++F++ +Q+P L +R+ +Y W+
Sbjct: 397 VGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWS 456
Query: 703 YTNGIDMNMVCMSVFQNESAAGIIV 727
+ GID V +S+ + A I V
Sbjct: 457 MSKGIDTEKV-LSICPKDMRADICV 480
Score = 44.3 bits (103), Expect = 4e-04
Identities = 22/74 (29%), Positives = 36/74 (48%)
Query: 60 MQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQE 119
MQK TC F++G T + I ++ Q E EV Y KN + I P++N+
Sbjct: 1 MQKSSTCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEH 60
Query: 120 GVAMMFIINFEYVT 133
++F+ F+ +T
Sbjct: 61 EKVVLFLCTFKDIT 74
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 327 bits (838), Expect = 2e-89
Identities = 167/385 (43%), Positives = 248/385 (64%), Gaps = 21/385 (5%)
Query: 352 IAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLV 411
+ P K + ++ +VL LG+D+LP+YK + P+ ILHY FK WDW+IL+L
Sbjct: 166 LTPMNKTEVVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCAFKTTWDWVILILT 225
Query: 412 IYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQN 471
YTAI PY+ +F + K+ + V+D +VD++F++DI++NF TT+V
Sbjct: 226 FYTAIMVPYNVSF------KTKQNNIAWL-----VLDSVVDVIFLVDIVLNFHTTFVGPG 274
Query: 472 EEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDE-TTTLIGLLKTARLLRLVRV 530
EV+SDP I ++Y K WF+ID+++ +P+D++ DE ++L LK RLLRL RV
Sbjct: 275 GEVISDPKLIRMNYLKTWFVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRV 334
Query: 531 ARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVER-PYLTDKI---GWLDSLGQ 586
ARKLD Y EYGAAVL+LL+C+F L+AHWLACIWY+IG+ E +T+ I WL L
Sbjct: 335 ARKLDHYLEYGAAVLVLLVCVFGLVAHWLACIWYSIGDYEVIDEVTNTIQIDSWLYQLAL 394
Query: 587 QIGK--RYNDSDS--SSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML 642
IG RYN S GPS YV++LYFT +SLT++GFGN++P T+ EK+FS+ +M+
Sbjct: 395 SIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMM 454
Query: 643 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT 702
+GSL+YA+IFGNV+ I Q++Y+ T RYH + V++F++ +Q+P L +R+ +Y W+
Sbjct: 455 VGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWS 514
Query: 703 YTNGIDMNMVCMSVFQNESAAGIIV 727
+ GID V +S+ + A I V
Sbjct: 515 MSKGIDTEKV-LSICPKDMRADICV 538
Score = 98.6 bits (244), Expect = 2e-20
Identities = 47/130 (36%), Positives = 75/130 (57%), Gaps = 2/130 (1%)
Query: 4 RRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKP 63
+RG VAPQNTFL I+R+ F++ NA++ + ++Y NDGFC+++G+ R DVMQK
Sbjct: 5 KRGLVAPQNTFLENIVRR--SSESSFLLGNAQIVDWPVVYSNDGFCKLSGYHRADVMQKS 62
Query: 64 CTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAM 123
TC F++G T + I ++ Q E EV Y KN + I P++N+ +
Sbjct: 63 STCSFMYGELTDKKTIEKVRQTFDNYESNCFEVLLYKKNRTPVWFYMQIAPIRNEHEKVV 122
Query: 124 MFIINFEYVT 133
+F+ F+ +T
Sbjct: 123 LFLCTFKDIT 132
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 325 bits (834), Expect = 7e-89
Identities = 167/372 (44%), Positives = 240/372 (64%), Gaps = 22/372 (5%)
Query: 352 IAPKV-KDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLL 410
+AP V K + ++ +VL LG+D+LP+YK + P+ ILHY FK WDW+IL+L
Sbjct: 168 LAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILIL 227
Query: 411 VIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQ 470
YTAI PY+ +F K R+ + VVD IVD++F++DI++NF TT+V
Sbjct: 228 TFYTAILVPYNVSF--------KTRQNNVAWL---VVDSIVDVIFLVDIVLNFHTTFVGP 276
Query: 471 NEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDE-TTTLIGLLKTARLLRLVR 529
EV+SDP I ++Y K WF+ID+++ +P+D++ DE ++L LK RLLRL R
Sbjct: 277 AGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGR 336
Query: 530 VARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKI----GWLDSLG 585
VARKLD Y EYGAAVL+LL+C+F L AHW+ACIWY+IG+ E K WL L
Sbjct: 337 VARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLA 396
Query: 586 QQIGKRYNDSDSSSG-----PSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICV 640
IG Y + S SG PS Y+++LYFT +SLTSVGFGN++P+T+ EKIF++ +
Sbjct: 397 MDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAI 456
Query: 641 MLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHA 700
M+IGSL+YA+IFGNV+ I Q++Y+ T RYH + V++F++ +Q+P L +R+ +Y
Sbjct: 457 MMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVST 516
Query: 701 WTYTNGIDMNMV 712
W+ + GID V
Sbjct: 517 WSMSRGIDTEKV 528
Score = 100 bits (249), Expect = 5e-21
Identities = 48/130 (36%), Positives = 76/130 (58%), Gaps = 2/130 (1%)
Query: 4 RRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKP 63
RRG VAPQNTFL I+R+ N F++ NA++ + I+Y NDGFC+++G+ R +VMQK
Sbjct: 7 RRGLVAPQNTFLENIVRRSNDTN--FVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKS 64
Query: 64 CTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAM 123
TC F++G T + I ++ Q E E+ Y KN + I P++N++ +
Sbjct: 65 STCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVV 124
Query: 124 MFIINFEYVT 133
+F+ F +T
Sbjct: 125 LFLCTFSDIT 134
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 316 bits (810), Expect = 4e-86
Identities = 167/399 (41%), Positives = 241/399 (60%), Gaps = 49/399 (12%)
Query: 352 IAPKV-KDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLL 410
+AP V K + ++ +VL LG+D+LP+YK + P+ ILHY FK WDW+IL+L
Sbjct: 168 LAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILIL 227
Query: 411 VIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQ 470
YTAI PY+ +F K R+ + VVD IVD++F++DI++NF TT+V
Sbjct: 228 TFYTAILVPYNVSF--------KTRQNNVAWL---VVDSIVDVIFLVDIVLNFHTTFVGP 276
Query: 471 NEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLL--------------------------- 503
EV+SDP I ++Y K WF+ID+++ +P+D++
Sbjct: 277 AGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPP 336
Query: 504 -IFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACI 562
+ G S ++L LK RLLRL RVARKLD Y EYGAAVL+LL+C+F L AHW+ACI
Sbjct: 337 PLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACI 396
Query: 563 WYAIGNVERPYLTDKI----GWLDSLGQQIGKRYNDSDSSS-----GPSIKDKYVTALYF 613
WY+IG+ E K WL L IG Y + S S GPS Y+++LYF
Sbjct: 397 WYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYF 456
Query: 614 TFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQM 673
T +SLTSVGFGN++P+T+ EKIF++ +M+IGSL+YA+IFGNV+ I Q++Y+ T RYH +
Sbjct: 457 TMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEML 516
Query: 674 LRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMV 712
V++F++ +Q+P L +R+ +Y W+ + GID V
Sbjct: 517 NSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKV 555
Score = 100 bits (249), Expect = 5e-21
Identities = 48/130 (36%), Positives = 76/130 (58%), Gaps = 2/130 (1%)
Query: 4 RRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKP 63
RRG VAPQNTFL I+R+ N F++ NA++ + I+Y NDGFC+++G+ R +VMQK
Sbjct: 7 RRGLVAPQNTFLENIVRRSNDTN--FVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKS 64
Query: 64 CTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAM 123
TC F++G T + I ++ Q E E+ Y KN + I P++N++ +
Sbjct: 65 STCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVV 124
Query: 124 MFIINFEYVT 133
+F+ F +T
Sbjct: 125 LFLCTFSDIT 134
>gi|38569493 potassium voltage-gated channel, subfamily H
(eag-related), member 3 [Homo sapiens]
Length = 1083
Score = 307 bits (786), Expect = 3e-83
Identities = 166/371 (44%), Positives = 229/371 (61%), Gaps = 43/371 (11%)
Query: 378 LPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRREC 437
LPEYK+ R + F +LH +A WD ILL +Y A+ PYS RE
Sbjct: 202 LPEYKVAAIRKSPFILLHCGALRATWDGFILLATLYVAVTVPYSVCV-------STAREP 254
Query: 438 GYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAA 497
+ P +V DL V+++FI+DI++NFRTT+V+++ +VV P I +HY WFL+D++AA
Sbjct: 255 SAARGPPSVCDLAVEVLFILDIVLNFRTTFVSKSGQVVFAPKSICLHYVTTWFLLDVIAA 314
Query: 498 IPFDLLIFGSGSDETTTLIG--LLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALI 555
+PFDLL + + G LLKT RLLRL+R+ +LDRYS+Y A VL LLM +FAL+
Sbjct: 315 LPFDLL----HAFKVNVYFGAHLLKTVRLLRLLRLLPRLDRYSQYSAVVLTLLMAVFALL 370
Query: 556 AHWLACIWYAIGNVERPYLTDK---IGWLDSLGQQIGKRY---------------NDSDS 597
AHW+AC+W+ IG E + IGWL L +++ Y +D+ S
Sbjct: 371 AHWVACVWFYIGQREIESSESELPEIGWLQELARRLETPYYLVGRRPAGGNSSGQSDNCS 430
Query: 598 SS------------GPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGS 645
SS GPS++ Y+T+LYF SSLTSVGFGNVS NT++EKIFSIC MLIG+
Sbjct: 431 SSSEANGTGLELLGGPSLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGA 490
Query: 646 LMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTN 705
LM+A +FGNV+AIIQR+Y+ YH + ++++IR H+IP PL+QR+ EYFQ W N
Sbjct: 491 LMHAVVFGNVTAIIQRMYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNN 550
Query: 706 GIDMNMVCMSV 716
GID + S+
Sbjct: 551 GIDTTELLQSL 561
Score = 135 bits (339), Expect = 2e-31
Identities = 61/144 (42%), Positives = 95/144 (65%), Gaps = 1/144 (0%)
Query: 1 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNC-AIIYCNDGFCEMTGFSRPDV 59
MP RG +APQNTFL TI +F+G + F++ NA+V ++YC+DGFC++TGFSR +V
Sbjct: 1 MPAMRGLLAPQNTFLDTIATRFDGTHSNFVLGNAQVAGLFPVVYCSDGFCDLTGFSRAEV 60
Query: 60 MQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQE 119
MQ+ C C FL+GP+T QI +AL +E K E+ Y K+G F C +IP+KN++
Sbjct: 61 MQRGCACSFLYGPDTSELVRQQIRKALDEHKEFKAELILYRKSGLPFWCLLDVIPIKNEK 120
Query: 120 GVAMMFIINFEYVTDNENAATPER 143
G +F+++ + +++ +N P+R
Sbjct: 121 GEVALFLVSHKDISETKNRGGPDR 144
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 136 bits (342), Expect = 8e-32
Identities = 92/334 (27%), Positives = 163/334 (48%), Gaps = 49/334 (14%)
Query: 391 FTILH-YSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDL 449
F I+H YS F+ WD +LLL++ I P F ++ + +P V ++
Sbjct: 252 FWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDE-----------NTTPWIVFNV 300
Query: 450 IVDIMFIIDILINFRT-TYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFG 506
+ D F+ID+++NFRT V N E++ DP +I + Y K WF++D +++IP D LI
Sbjct: 301 VSDTFFLIDLVLNFRTGIVVEDNTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVE 360
Query: 507 SGSDET-------------TTLIGLLKTARLLRLVRVARKLDR-----YSEYGAAVLML- 547
+ D T ++ LL+ RL RL+R + + Y A V ++
Sbjct: 361 TRIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIVN 420
Query: 548 LMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKY 607
L+ + L+ HW C+ + + P L D + D I N+S +Y
Sbjct: 421 LIGMMLLLCHWDGCLQFLV-----PMLQD---FPDDCWVSINNMVNNSWGK-------QY 465
Query: 608 VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA 667
AL+ S + +G+G +P S+ ++ M++G+ YA G+ +A+IQ L S
Sbjct: 466 SYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRR 525
Query: 668 RYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW 701
+Y + +V++++ FH++P RQR+ +Y++H +
Sbjct: 526 QYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRY 559
>gi|116325989 hyperpolarization activated cyclic nucleotide-gated
potassium channel 1 [Homo sapiens]
Length = 890
Score = 133 bits (335), Expect = 5e-31
Identities = 85/334 (25%), Positives = 167/334 (50%), Gaps = 49/334 (14%)
Query: 391 FTILH-YSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDL 449
F I+H YS F+ WD ++L++++ + P F + +P + ++
Sbjct: 132 FWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQ-----------TTTPWIIFNV 180
Query: 450 IVDIMFIIDILINFRTTYVNQNE-EVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFG 506
D +F++D+++NFRT VN++ E++ DP I ++Y K WF++D +++IP D LI
Sbjct: 181 ASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVE 240
Query: 507 SGSDET-------------TTLIGLLKTARLLRLVRVARKLDRYS----EYGAAVLML-- 547
G D T ++ LL+ RL RL+R + + + +AV+ +
Sbjct: 241 KGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFN 300
Query: 548 LMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKY 607
L+ + L+ HW C+ + + P L D + + + NDS +Y
Sbjct: 301 LIGMMLLLCHWDGCLQFLV-----PLLQD---FPPDCWVSLNEMVNDSWGK-------QY 345
Query: 608 VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA 667
AL+ S + +G+G +P + S+ ++ M++G+ YA G+ +A+IQ L S
Sbjct: 346 SYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRR 405
Query: 668 RYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW 701
+Y + +V++++ FH++P +RQ++ +Y++H +
Sbjct: 406 QYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRY 439
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 132 bits (332), Expect = 1e-30
Identities = 87/334 (26%), Positives = 161/334 (48%), Gaps = 53/334 (15%)
Query: 393 ILH-YSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIV 451
I+H YS F+ WD+ +LL ++ I P F ++ + +P V +++
Sbjct: 203 IIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDE-----------TTAPWIVFNVVS 251
Query: 452 DIMFIIDILINFRTTYV-NQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFD--LLIFGSG 508
D F++D+++NFRT V N E++ DP KI Y + WF++D V++IP D LI G
Sbjct: 252 DTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKG 311
Query: 509 SDET-------------TTLIGLLKTARLLRLVRVARKLDR--YSEYGAAVLMLLMC--- 550
D T ++ LL+ RL RL+R + + + Y A ++ +C
Sbjct: 312 IDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLI 371
Query: 551 -IFALIAHWLACIWYAIGNVERPYLTD--KIGWLDSLGQQIGKRYNDSDSSSGPSIKDKY 607
+ L+ HW C+ + + P L D + W+ G S + Y
Sbjct: 372 SMMLLLCHWDGCLQFLV-----PMLQDFPRNCWVSINGMV------------NHSWSELY 414
Query: 608 VTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTA 667
AL+ S + +G+G +P + ++ ++ M++G+ YA G+ +A+IQ L S
Sbjct: 415 SFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRR 474
Query: 668 RYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW 701
+Y + +V++++ FH++P RQ++ +Y++H +
Sbjct: 475 QYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY 508
>gi|38327037 hyperpolarization activated cyclic nucleotide-gated
potassium channel 3 [Homo sapiens]
Length = 774
Score = 119 bits (299), Expect = 8e-27
Identities = 91/335 (27%), Positives = 157/335 (46%), Gaps = 53/335 (15%)
Query: 393 ILH-YSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIV 451
I+H YS F+ WD ++LLL++ I P F +EE P V +++
Sbjct: 85 IIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFF---KEENS--------PPWIVFNVLS 133
Query: 452 DIMFIIDILINFRT-TYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSD 510
D F++D+++NFRT V + E++ P I Y + WFL+D++++IP D IF
Sbjct: 134 DTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDY-IFLVVEL 192
Query: 511 ETTTLIGLLKTARLLRLVRVAR--------KLDRYSEY--------------GAAVLML- 547
E + KTAR LR+VR + +L R Y +AV+ +
Sbjct: 193 EPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIF 252
Query: 548 -LMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDK 606
L+ + L+ HW C+ + + P L D + I N S +
Sbjct: 253 NLIGMMLLLCHWDGCLQFLV-----PMLQD---FPPDCWVSINHMVNHSWGR-------Q 297
Query: 607 YVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGT 666
Y AL+ S + +G+G +P + ++ M++G+ YA G+ +A+IQ L S
Sbjct: 298 YSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSR 357
Query: 667 ARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAW 701
+Y + +V++++ FH++P RQR+ EY++H +
Sbjct: 358 RQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY 392
>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
[Homo sapiens]
Length = 759
Score = 103 bits (256), Expect = 7e-22
Identities = 103/439 (23%), Positives = 194/439 (44%), Gaps = 41/439 (9%)
Query: 273 ASSVHDIEGFGVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNF 332
AS+ + E H + F + +G + + L G+ + N+N S ++ P+
Sbjct: 118 ASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE----- 172
Query: 333 SEVKTEKKNSSPPSSDKTIIA--PKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINK 390
E K +KK S DK P+ K + + +K + S D E K + I+
Sbjct: 173 -EKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKS--KDKKEEEKKEVVVIDP 229
Query: 391 FTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLI 450
+Y+ W + I L V+Y A F +E + Y ++D +
Sbjct: 230 SGNTYYN-----WLFCITLPVMYNWTMVIARACF-----DELQSDYLEYWL----ILDYV 275
Query: 451 VDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSD 510
DI+++ID+ + RT Y+ Q V + I + F +D+++ IP DLL F G +
Sbjct: 276 SDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWN 335
Query: 511 ETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAV-LMLLMCIFALIAHWLACIWYAIGNV 569
I L + R R+ ++ + + Y + L+ +I HW AC++Y+I
Sbjct: 336 YPE--IRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKA 393
Query: 570 ERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPN 629
IG+ + Y D + + KYV +LY++ +LT++G P
Sbjct: 394 --------IGFGNDTWV-----YPDINDPEFGRLARKYVYSLYWSTLTLTTIG-ETPPPV 439
Query: 630 TNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPL 689
+SE +F + LIG L++A+I GN+ ++I + + A + ++ +K+++ F + +
Sbjct: 440 RDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDM 499
Query: 690 RQRLEEYFQHAWTYTNGID 708
+R+ ++F + WT +D
Sbjct: 500 EKRVIKWFDYLWTNKKTVD 518
>gi|71143141 cyclic nucleotide gated channel alpha 1 isoform 2 [Homo
sapiens]
Length = 690
Score = 103 bits (256), Expect = 7e-22
Identities = 103/439 (23%), Positives = 194/439 (44%), Gaps = 41/439 (9%)
Query: 273 ASSVHDIEGFGVHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNF 332
AS+ + E H + F + +G + + L G+ + N+N S ++ P+
Sbjct: 49 ASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE----- 103
Query: 333 SEVKTEKKNSSPPSSDKTIIA--PKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINK 390
E K +KK S DK P+ K + + +K + S D E K + I+
Sbjct: 104 -EKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKS--KDKKEEEKKEVVVIDP 160
Query: 391 FTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLI 450
+Y+ W + I L V+Y A F +E + Y ++D +
Sbjct: 161 SGNTYYN-----WLFCITLPVMYNWTMVIARACF-----DELQSDYLEYWL----ILDYV 206
Query: 451 VDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSD 510
DI+++ID+ + RT Y+ Q V + I + F +D+++ IP DLL F G +
Sbjct: 207 SDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWN 266
Query: 511 ETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAV-LMLLMCIFALIAHWLACIWYAIGNV 569
I L + R R+ ++ + + Y + L+ +I HW AC++Y+I
Sbjct: 267 YPE--IRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKA 324
Query: 570 ERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPN 629
IG+ + Y D + + KYV +LY++ +LT++G P
Sbjct: 325 --------IGFGNDTWV-----YPDINDPEFGRLARKYVYSLYWSTLTLTTIG-ETPPPV 370
Query: 630 TNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPL 689
+SE +F + LIG L++A+I GN+ ++I + + A + ++ +K+++ F + +
Sbjct: 371 RDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDM 430
Query: 690 RQRLEEYFQHAWTYTNGID 708
+R+ ++F + WT +D
Sbjct: 431 EKRVIKWFDYLWTNKKTVD 449
>gi|120433600 cyclic nucleotide gated channel alpha 3 isoform 2
[Homo sapiens]
Length = 676
Score = 93.2 bits (230), Expect = 8e-19
Identities = 70/276 (25%), Positives = 132/276 (47%), Gaps = 25/276 (9%)
Query: 446 VVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHY-FKGWFLIDMVAAIPFDLLI 504
V+D D+++++D+L+ RT ++ Q +VSD ++ HY F +D+++ +P DL
Sbjct: 187 VLDYSADVLYVLDVLVRARTGFLEQGL-MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAY 245
Query: 505 FGSGSDETTTLIG-LLKTARLLRLVRVARKLDRYSEY---GAAVLMLLMCIFALIAHWLA 560
G++ LLK +RL Y G VL +L +I HW A
Sbjct: 246 LKVGTNYPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYIL-----IIIHWNA 300
Query: 561 CIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTS 620
CI++AI + TD W+ Y + + KY+ +LY++ +LT+
Sbjct: 301 CIYFAISKFIG-FGTDS--WV----------YPNISIPEHGRLSRKYIYSLYWSTLTLTT 347
Query: 621 VGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFI 680
+G P + E +F + L+G L++A+I GNV ++I + + A + ++ +K+++
Sbjct: 348 IG-ETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYM 406
Query: 681 RFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSV 716
+F ++ L R+ +F + W +D V S+
Sbjct: 407 QFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSL 442
>gi|4502917 cyclic nucleotide gated channel alpha 3 isoform 1 [Homo
sapiens]
Length = 694
Score = 93.2 bits (230), Expect = 8e-19
Identities = 70/276 (25%), Positives = 132/276 (47%), Gaps = 25/276 (9%)
Query: 446 VVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHY-FKGWFLIDMVAAIPFDLLI 504
V+D D+++++D+L+ RT ++ Q +VSD ++ HY F +D+++ +P DL
Sbjct: 205 VLDYSADVLYVLDVLVRARTGFLEQGL-MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAY 263
Query: 505 FGSGSDETTTLIG-LLKTARLLRLVRVARKLDRYSEY---GAAVLMLLMCIFALIAHWLA 560
G++ LLK +RL Y G VL +L +I HW A
Sbjct: 264 LKVGTNYPEVRFNRLLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYIL-----IIIHWNA 318
Query: 561 CIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTS 620
CI++AI + TD W+ Y + + KY+ +LY++ +LT+
Sbjct: 319 CIYFAISKFIG-FGTDS--WV----------YPNISIPEHGRLSRKYIYSLYWSTLTLTT 365
Query: 621 VGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFI 680
+G P + E +F + L+G L++A+I GNV ++I + + A + ++ +K+++
Sbjct: 366 IG-ETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYM 424
Query: 681 RFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVCMSV 716
+F ++ L R+ +F + W +D V S+
Sbjct: 425 QFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSL 460
>gi|42718011 cyclic nucleotide gated channel alpha 2 [Homo sapiens]
Length = 664
Score = 88.2 bits (217), Expect = 2e-17
Identities = 71/268 (26%), Positives = 128/268 (47%), Gaps = 25/268 (9%)
Query: 446 VVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLI 504
V+D + D+++I D+ I RT ++ Q +V D K+ +Y F +D+ + IP DL+
Sbjct: 177 VLDYVSDVVYIADLFIRLRTGFLEQGL-LVKDTKKLRDNYIHTLQFKLDVASIIPTDLIY 235
Query: 505 FGSGSDETTTLIGLLKTARLLRLVRVARKLDRY---SEYGAAVLMLLMCIFAL-IAHWLA 560
F ++ RLL R+ DR + Y + + ++ L I HW A
Sbjct: 236 FAVDIHSPE-----VRFNRLLHFARMFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNA 290
Query: 561 CIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTS 620
CI+YAI IG+ G N +D G ++ Y+ LY++ +LT+
Sbjct: 291 CIYYAISK--------SIGF----GVDTWVYPNITDPEYGYLARE-YIYCLYWSTLTLTT 337
Query: 621 VGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFI 680
+G P + E +F I LIG L++A+I GNV ++I + + A + ++ VK ++
Sbjct: 338 IG-ETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYM 396
Query: 681 RFHQIPNPLRQRLEEYFQHAWTYTNGID 708
+F ++ + ++ +F + WT +D
Sbjct: 397 QFRKVSKGMEAKVIRWFDYLWTNKKTVD 424
>gi|82617546 cyclic nucleotide gated channel alpha 4 [Homo sapiens]
Length = 575
Score = 87.4 bits (215), Expect = 4e-17
Identities = 63/261 (24%), Positives = 127/261 (48%), Gaps = 29/261 (11%)
Query: 446 VVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLI 504
V+D D+++++D+++ F T ++ Q VV D +I+ Y + W F +D+ + +P D++
Sbjct: 71 VLDYTSDLLYLLDMVVRFHTGFLEQGILVV-DKGRISSRYVRTWSFFLDLASLMPTDVVY 129
Query: 505 FGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGA-----AVLMLLMCIFALIAHWL 559
G T L+ R LR R+ DR A + L++ IF +I HW
Sbjct: 130 VRLGPHTPT-----LRLNRFLRAPRLFEAFDRTETRTAYPNAFRIAKLMLYIFVVI-HWN 183
Query: 560 ACIWYAIGNVERPYL-TDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSL 618
+C+++A+ YL + W+ Y D ++ +Y+ + YF+ L
Sbjct: 184 SCLYFALSR----YLGFGRDAWV----------YPDPAQPGFERLRRQYLYSFYFSTLIL 229
Query: 619 TSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKE 678
T+VG P E +F + L+ + +A+I G++S++I + + A ++ VK+
Sbjct: 230 TTVG-DTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHALVKK 288
Query: 679 FIRFHQIPNPLRQRLEEYFQH 699
+++ + L +R+ +++QH
Sbjct: 289 YMKLQHVNRKLERRVIDWYQH 309
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/258 (18%), Positives = 113/258 (43%), Gaps = 27/258 (10%)
Query: 446 VVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLI 504
++D + D+++ +DI + + ++++D + +Y K F +D+++ +P D L
Sbjct: 693 LMDYLCDLIYFLDITVFQTRLQFVRGGDIITDKKDMRNNYLKSRRFKMDLLSLLPLDFLY 752
Query: 505 FGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFAL-IAHWLACIW 563
G + LLRL R + + + E+ + + +L + + A +
Sbjct: 753 LKVGVNP------------LLRLPRCLKYM-AFFEFNSRLESILSKAYVYRVIRTTAYLL 799
Query: 564 YAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGF 623
Y++ +L + + S Q +G + D + + Y+ YF +L ++G
Sbjct: 800 YSL------HLNSCLYYWASAYQGLGSTHWVYDG-----VGNSYIRCYYFAVKTLITIG- 847
Query: 624 GNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFH 683
G P T E +F + G ++ + G + ++ +G Y M +++ F+
Sbjct: 848 GLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFY 907
Query: 684 QIPNPLRQRLEEYFQHAW 701
+IP ++ R++ ++++ W
Sbjct: 908 KIPKSVQNRVKTWYEYTW 925
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Query: 581 LDSLGQQIGKRYNDSDS--SSGPSI-KDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFS 637
LDSL + + + Y + S S+ S+ + + V + +F+ S++T++G+GN+SPNT + ++F
Sbjct: 74 LDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFC 133
Query: 638 ICVMLIGSLMYASIFGNVSAIIQR 661
I L+G + + + ++Q+
Sbjct: 134 IFFALVGIPLNLVVLNRLGHLMQQ 157
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Query: 581 LDSLGQQIGKRYNDSDS--SSGPSI-KDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFS 637
LDSL + + + Y + S S+ S+ + + V + +F+ S++T++G+GN+SPNT + ++F
Sbjct: 74 LDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFC 133
Query: 638 ICVMLIGSLMYASIFGNVSAIIQR 661
I L+G + + + ++Q+
Sbjct: 134 IFFALVGIPLNLVVLNRLGHLMQQ 157
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 40.4 bits (93), Expect = 0.006
Identities = 47/213 (22%), Positives = 92/213 (43%), Gaps = 36/213 (16%)
Query: 494 MVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFA 553
++A++P ++ G+ + T + L+ ++LR++R+ R+ + G+A+ C +
Sbjct: 206 LIASVP--VVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAI-----CAHS 258
Query: 554 --LIAHWLACIWYAIGNVERPYLTDK-IGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTA 610
LI W I + YL +K + +D+ G+++ + + + Y A
Sbjct: 259 KELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF------------ETYADA 306
Query: 611 LYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYH 670
L++ +L ++G+G+ +P T ++ + LIG +A G L SG A
Sbjct: 307 LWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAG-------ILGSGLALKV 359
Query: 671 MQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTY 703
+ R K F R+ E Q AW Y
Sbjct: 360 QEQHRQKHF-------EKRRKPAAELIQAAWRY 385
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 39.7 bits (91), Expect = 0.010
Identities = 40/164 (24%), Positives = 79/164 (48%), Gaps = 24/164 (14%)
Query: 491 LIDMVAAIPFDLLIFG---SGSDETTTLIGLLKTARLLRLVRVAR--KLDRYSEYGAAVL 545
+ID++A +PF + + SGS T L + + ++LRL+R R KL R+S ++
Sbjct: 277 IIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLG 336
Query: 546 MLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKD 605
M + + + L ++ ++G I ++ + D+ +S P
Sbjct: 337 MTITQCYEEVG--LLLLFLSVG----------ISIFSTVEYFAEQSIPDTTFTSVPC--- 381
Query: 606 KYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYA 649
A ++ +S+T+VG+G++ P+T + KI + +L G L+ A
Sbjct: 382 ----AWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLA 421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,957,958
Number of Sequences: 37866
Number of extensions: 1174922
Number of successful extensions: 3088
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2911
Number of HSP's gapped (non-prelim): 133
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.