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Search of human proteins with 27262630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 867 0.0
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 610 e-175
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 610 e-175
gi|16262452 cingulin [Homo sapiens] 51 2e-06
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 51 2e-06
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 51 2e-06
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 51 2e-06
gi|38569484 kinesin family member 21A [Homo sapiens] 48 2e-05
gi|4758646 kinesin family member 3B [Homo sapiens] 48 2e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 4e-05
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 46 8e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 46 8e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 1e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 45 1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 45 1e-04
gi|28460688 taxilin [Homo sapiens] 45 1e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 45 2e-04
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 45 2e-04
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 45 2e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 2e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 2e-04
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 44 2e-04
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 44 2e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 2e-04
gi|71061468 centromere protein E [Homo sapiens] 44 2e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 3e-04
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 44 3e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 3e-04
>gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
sapiens]
Length = 449
Score = 867 bits (2240), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60
MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP
Sbjct: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60
Query: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120
AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG
Sbjct: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120
Query: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW 180
EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW
Sbjct: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW 180
Query: 181 DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240
DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH
Sbjct: 181 DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240
Query: 241 DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI 300
DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI
Sbjct: 241 DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI 300
Query: 301 EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP 360
EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP
Sbjct: 301 EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP 360
Query: 361 TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM 420
TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM
Sbjct: 361 TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM 420
Query: 421 EEEAENQAESRAAVEGTVEAGATVESTAC 449
EEEAENQAESRAAVEGTVEAGATVESTAC
Sbjct: 421 EEEAENQAESRAAVEGTVEAGATVESTAC 449
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 610 bits (1574), Expect = e-175
Identities = 341/468 (72%), Positives = 366/468 (78%), Gaps = 23/468 (4%)
Query: 4 ESTATAAVAAELVSAD--KIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHL------- 54
E+ A AV +LV + E+ P +T A + +++ SE + G L
Sbjct: 322 ENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVN 381
Query: 55 ---VMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALE 111
V+GD + L K G E A + +L+ E+ G+ ++
Sbjct: 382 GPSVVGD-QTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 440
Query: 112 GVHVEEEEGEKTEDESLVENNDNI----------DETEGSEEDDKENDKTEEMPNDSVLE 161
+ + ED+ + N+ +ETEGSEEDDKENDKTEEMPNDSVLE
Sbjct: 441 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 500
Query: 162 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221
NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ
Sbjct: 501 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 560
Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281
AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV
Sbjct: 561 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 620
Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 341
LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS
Sbjct: 621 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 680
Query: 342 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 401
GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE
Sbjct: 681 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 740
Query: 402 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 449
VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC
Sbjct: 741 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 788
Score = 280 bits (717), Expect = 1e-75
Identities = 208/493 (42%), Positives = 273/493 (55%), Gaps = 49/493 (9%)
Query: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60
MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP
Sbjct: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60
Query: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120
AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG
Sbjct: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120
Query: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLEL-- 178
EKTEDESLVENNDNIDE E ++ D E E+KSL + E ++ + E+
Sbjct: 121 EKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEK 180
Query: 179 -AWDMLDLAKIIFKRQE------------TKEAQLYAAQAHLKLGEV-SVESENYVQAVE 224
+ +D++K + QE ++EA+ AA EV S + E V E
Sbjct: 181 GGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAE 240
Query: 225 EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQ---YDEAVAQFSKSIEVIENRMAV 281
E +S Q E ++ E ++ ++ + ++ V K +E
Sbjct: 241 EEKSVSGTDVQE-ECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAES 299
Query: 282 LNEQVKEAE-GSSAEYKKEIEELKELLPEIREKI--EDAKESQRSGNVAELALKATLVES 338
L+ VK + G +K + E + E++ ++ ++ S V A +A+ VE+
Sbjct: 300 LDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEA 359
Query: 339 -STSGFTPG---------GGGSSVSMIASRKPTDGASSSNCVTD------ISHLVRKKRK 382
S PG G + S++ + P + +S +T+ + VR K
Sbjct: 360 GSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLV 419
Query: 383 PEEE----SPRKDDAKKAKQEPEVNGGSGDAVP------SGNEVSENMEEEAENQAESRA 432
P +E S + +A + +V G+ + P + NE ++ EE+ + E+
Sbjct: 420 PSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEG 479
Query: 433 AVEGTVEAGATVE 445
+ E E T E
Sbjct: 480 SEEDDKENDKTEE 492
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 610 bits (1574), Expect = e-175
Identities = 341/468 (72%), Positives = 366/468 (78%), Gaps = 23/468 (4%)
Query: 4 ESTATAAVAAELVSAD--KIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHL------- 54
E+ A AV +LV + E+ P +T A + +++ SE + G L
Sbjct: 324 ENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVN 383
Query: 55 ---VMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALE 111
V+GD + L K G E A + +L+ E+ G+ ++
Sbjct: 384 GPSVVGD-QTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 442
Query: 112 GVHVEEEEGEKTEDESLVENNDNI----------DETEGSEEDDKENDKTEEMPNDSVLE 161
+ + ED+ + N+ +ETEGSEEDDKENDKTEEMPNDSVLE
Sbjct: 443 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 502
Query: 162 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221
NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ
Sbjct: 503 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 562
Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281
AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV
Sbjct: 563 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 622
Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 341
LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS
Sbjct: 623 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 682
Query: 342 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 401
GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE
Sbjct: 683 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 742
Query: 402 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 449
VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC
Sbjct: 743 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 790
Score = 217 bits (552), Expect = 2e-56
Identities = 172/462 (37%), Positives = 240/462 (51%), Gaps = 49/462 (10%)
Query: 32 DKVESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY 91
+++ LDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY
Sbjct: 34 NRIIHLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY 93
Query: 92 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKT 151
GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDE E ++ D
Sbjct: 94 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAM 153
Query: 152 EEMPNDSVLENKSLQENEEEEIGNLEL---AWDMLDLAKIIFKRQE------------TK 196
E E+KSL + E ++ + E+ + +D++K + QE ++
Sbjct: 154 GEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSE 213
Query: 197 EAQLYAAQAHLKLGEV-SVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAY 255
EA+ AA EV S + E V EE +S Q E ++ E ++ ++
Sbjct: 214 EAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQE-ECREKGGQEKQGEVIVSI 272
Query: 256 GYNSQ---YDEAVAQFSKSIEVIENRMAVLNEQVKEAE-GSSAEYKKEIEELKELLPEIR 311
+ ++ V K +E L+ VK + G +K + E +
Sbjct: 273 EEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVL 332
Query: 312 EKI--EDAKESQRSGNVAELALKATLVES-STSGFTPG---------GGGSSVSMIASRK 359
E++ ++ ++ S V A +A+ VE+ S PG G + S++ +
Sbjct: 333 EQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQT 392
Query: 360 PTDGASSSNCVTD------ISHLVRKKRKPEEE----SPRKDDAKKAKQEPEVNGGSGDA 409
P + +S +T+ + VR K P +E S + +A + +V G+ +
Sbjct: 393 PIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEK 452
Query: 410 VP------SGNEVSENMEEEAENQAESRAAVEGTVEAGATVE 445
P + NE ++ EE+ + E+ + E E T E
Sbjct: 453 SPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 494
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/241 (20%), Positives = 112/241 (46%), Gaps = 5/241 (2%)
Query: 97 ELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPN 156
+ AR++ +L L+G+ E E ++++D+ + ++ E + E T E+
Sbjct: 930 DTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLT 989
Query: 157 DSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQ-ETKEAQLYAAQAHLKLGEVSVE 215
D V + + E+ A L+ KI +RQ + + +L +++ K +
Sbjct: 990 DRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQ 1049
Query: 216 SENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY-DEAVAQFSKSIEV 274
E+ Q ++E ++ L++ +R L +L + Q+ ++ Q S ++
Sbjct: 1050 LESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKA 1109
Query: 275 IENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED-AKESQR--SGNVAELAL 331
++ ++ E+++ +G + ++E+EE E+ +++ +I+ K+S R S + AE AL
Sbjct: 1110 LKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAESAL 1169
Query: 332 K 332
K
Sbjct: 1170 K 1170
Score = 37.4 bits (85), Expect = 0.028
Identities = 58/270 (21%), Positives = 109/270 (40%), Gaps = 25/270 (9%)
Query: 73 LGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTE--DESLVE 130
L ++ ET+ E G + K+ +L + +L +E +EEE GEK E L +
Sbjct: 557 LQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQ 616
Query: 131 NNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ-ENEEEEIGNLELAWDM-LDLAKI 188
+ +T E KE +T+E E K LQ E + +E+ ++ LA +
Sbjct: 617 ARASAGDTRQVEVLKKELLRTQE-------ELKELQAERQSQEVAGRHRDRELEKQLAVL 669
Query: 189 IFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETH 248
+ +E + Q L ++ + E +A ++ + Q A + L ET
Sbjct: 670 RVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRET- 728
Query: 249 YQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP 308
E +F + I +E ++ V E A + +++ L+
Sbjct: 729 -------------QEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQ 775
Query: 309 EIREKIEDAKESQRSGNVAELALKATLVES 338
++ E + ++E + S A+ AL+A L E+
Sbjct: 776 QLEEALNASQEEEGSLAAAKRALEARLEEA 805
Score = 34.3 bits (77), Expect = 0.24
Identities = 61/235 (25%), Positives = 100/235 (42%), Gaps = 30/235 (12%)
Query: 106 LGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDK-----ENDKTEEMPNDSVL 160
L L + VE + G + E+++L + EE K E + T + +
Sbjct: 662 LEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAV 721
Query: 161 ENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY-----AAQAHLKLGEVSVE 215
E +L+E +EE N E +L L Q+ KE + A +A L+ +E
Sbjct: 722 ET-TLRETQEE---NDEFRRRILGL------EQQLKETRGLVDGGEAVEARLRDKLQRLE 771
Query: 216 SENYVQAVEEFQSCLNLQEQYLEAHDRLLAET--HYQLGLA-YGYNSQ-YDEAVAQFSKS 271
+E Q +EE + +E L A R L Q GLA G Q + A+ + K
Sbjct: 772 AEK--QQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQ 829
Query: 272 IEVIENRMAVLNEQVKEAEGSSAEYKKEIEEL----KELLPEIREKIEDAKESQR 322
EV+ A L EQ + + + KE+E++ K+ L +++ ++ED KE R
Sbjct: 830 REVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKAR 884
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 50.8 bits (120), Expect = 2e-06
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 17/201 (8%)
Query: 115 VEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ-ENEEEEI 173
V++ E T+ + + E+N ++ + E +KE K +++ N + + L+ + ++E++
Sbjct: 784 VQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDV 843
Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQ-LYAAQAHLKLGEVSVESENYVQAVEEFQSCLNL 232
N +L+ D ++ + Q+TK + L A LKL E E E + + L L
Sbjct: 844 LNNKLS----DALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLIL 899
Query: 233 QEQYLEA-HDRLLAETHYQLGLAYGYNS---QYDEAVAQFSKSIEVIENRMAVLNEQVKE 288
Q++ ++A D ++ H G+ +Y E + Q +++I +E ++ + + K+
Sbjct: 900 QQKMVKALQDEQESQRH-------GFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKK 952
Query: 289 AEGSSAEYKKEIEELKELLPE 309
EG A K KE P+
Sbjct: 953 IEGEIATLKDNDPAPKEERPQ 973
Score = 32.0 bits (71), Expect = 1.2
Identities = 71/319 (22%), Positives = 121/319 (37%), Gaps = 33/319 (10%)
Query: 39 VDSEAKKLLGLG-----QKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGK 93
++SE +K+ L QK + +I +EA KK + N + K
Sbjct: 777 LESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQ-----K 831
Query: 94 SLLELARMENGVLGNALEGVHVEEEEGEKTE-DESLVENNDNIDETEGSEEDDKENDKTE 152
LEL + VL N L EE +KT+ ESL + + E E + K
Sbjct: 832 EELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMI 891
Query: 153 EMPNDSVLEN---KSLQENEEEEIGNLELAWDMLDLAKIIFKRQET----KEAQLYAAQA 205
+ +L+ K+LQ+ +E + E ++++ + I + +T +E Q
Sbjct: 892 MVEERLILQQKMVKALQDEQESQRHGFE--EEIMEYKEQIKQHAQTIVSLEEKLQKVTQH 949
Query: 206 HLKL-GEVSVESENYVQAVEEF-QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDE 263
H K+ GE++ +N EE Q L A D L A E
Sbjct: 950 HKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQKEILSQQE 1009
Query: 264 AVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE--------YKKEIEELKELLPEIREKIE 315
+ + K + +RM+ L ++ E + E KE+ LKE + ++ +E
Sbjct: 1010 VIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVE 1069
Query: 316 DAKESQRSGNVAELALKAT 334
+ R E AL+A+
Sbjct: 1070 ---KKDRELKALEEALRAS 1085
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/260 (24%), Positives = 107/260 (41%), Gaps = 17/260 (6%)
Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169
LE V V E+ T +E D+ E EE K+ + N++ N +L++ +
Sbjct: 395 LEDVQVREKLKHATSKAKKLEKQLQKDK-EKVEEFKSIPAKSNNIINETTTRNNALEKEK 453
Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229
E+E L+ D L +QET+ Q +L S ++ QS
Sbjct: 454 EKEEKKLKEVMDSL--------KQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSE 505
Query: 230 LNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEA 289
L++ YL H+ ++ QL A E + + +I IE ++ +++KE
Sbjct: 506 LDI---YLSRHNTAVS----QLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK 558
Query: 290 EGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG 349
E + +E K L+ ++ +K+E+AK S L A +++ SG PG G
Sbjct: 559 EKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-IIQEKKSGRIPGIYG 617
Query: 350 SSVSMIASRKPTDGASSSNC 369
+ A + D A SS C
Sbjct: 618 RLGDLGAIDEKYDVAISSCC 637
Score = 32.0 bits (71), Expect = 1.2
Identities = 51/220 (23%), Positives = 97/220 (44%), Gaps = 45/220 (20%)
Query: 122 KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWD 181
KT D +L + D++ TE KE TE+ +D E KSL++ E + N A +
Sbjct: 928 KTADRNLQKAQDSVLRTE------KEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEE 981
Query: 182 MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHD 241
L ++ +L L E+ V EN A+++ + L+ + ++ H
Sbjct: 982 SL--------------PEIQKEHRNL-LQELKVIQEN-EHALQKDALSIKLKLEQIDGH- 1024
Query: 242 RLLAETHYQLGLAYGYNSQY------DEAVAQFS----KSIEVIENRMAVLNE------- 284
+AE + ++ + S+ D + + S + +E I+N ++ N+
Sbjct: 1025 --IAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEAR 1082
Query: 285 --QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322
++K G+ AEYKK+ E + + E+ +KI ++S R
Sbjct: 1083 CHEMKPNLGAIAEYKKKEELYLQRVAEL-DKITYERDSFR 1121
Score = 30.0 bits (66), Expect = 4.4
Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 14/115 (12%)
Query: 210 GEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFS 269
GE ++ E E F+ ++ + Y+ + +AE Q + E + +
Sbjct: 300 GEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQ-------KEKIHEDTKEIN 352
Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP-------EIREKIEDA 317
+ ++ N M N+ VK+ E + K IEE KE ++REK++ A
Sbjct: 353 EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHA 407
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/260 (24%), Positives = 107/260 (41%), Gaps = 17/260 (6%)
Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169
LE V V E+ T +E D+ E EE K+ + N++ N +L++ +
Sbjct: 395 LEDVQVREKLKHATSKAKKLEKQLQKDK-EKVEEFKSIPAKSNNIINETTTRNNALEKEK 453
Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229
E+E L+ D L +QET+ Q +L S ++ QS
Sbjct: 454 EKEEKKLKEVMDSL--------KQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSE 505
Query: 230 LNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEA 289
L++ YL H+ ++ QL A E + + +I IE ++ +++KE
Sbjct: 506 LDI---YLSRHNTAVS----QLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK 558
Query: 290 EGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG 349
E + +E K L+ ++ +K+E+AK S L A +++ SG PG G
Sbjct: 559 EKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-IIQEKKSGRIPGIYG 617
Query: 350 SSVSMIASRKPTDGASSSNC 369
+ A + D A SS C
Sbjct: 618 RLGDLGAIDEKYDVAISSCC 637
Score = 32.0 bits (71), Expect = 1.2
Identities = 51/220 (23%), Positives = 97/220 (44%), Gaps = 45/220 (20%)
Query: 122 KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWD 181
KT D +L + D++ TE KE TE+ +D E KSL++ E + N A +
Sbjct: 928 KTADRNLQKAQDSVLRTE------KEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEE 981
Query: 182 MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHD 241
L ++ +L L E+ V EN A+++ + L+ + ++ H
Sbjct: 982 SL--------------PEIQKEHRNL-LQELKVIQEN-EHALQKDALSIKLKLEQIDGH- 1024
Query: 242 RLLAETHYQLGLAYGYNSQY------DEAVAQFS----KSIEVIENRMAVLNE------- 284
+AE + ++ + S+ D + + S + +E I+N ++ N+
Sbjct: 1025 --IAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEAR 1082
Query: 285 --QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322
++K G+ AEYKK+ E + + E+ +KI ++S R
Sbjct: 1083 CHEMKPNLGAIAEYKKKEELYLQRVAEL-DKITYERDSFR 1121
Score = 30.0 bits (66), Expect = 4.4
Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 14/115 (12%)
Query: 210 GEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFS 269
GE ++ E E F+ ++ + Y+ + +AE Q + E + +
Sbjct: 300 GEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQ-------KEKIHEDTKEIN 352
Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP-------EIREKIEDA 317
+ ++ N M N+ VK+ E + K IEE KE ++REK++ A
Sbjct: 353 EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHA 407
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 48.1 bits (113), Expect = 2e-05
Identities = 52/219 (23%), Positives = 94/219 (42%), Gaps = 36/219 (16%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPND-------SVL 160
N LE +E + E+E E D+ID E S+E D E+D+ D +
Sbjct: 584 NELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAI 643
Query: 161 ENKSLQ--ENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESEN 218
+ K + EN ++ + L+ ++ K++ + + ++ QL Q LG V SE
Sbjct: 644 KQKLIDELENSQKRLQTLKKQYE----EKLMMLQHKIRDTQLERDQVLQNLGSVESYSEE 699
Query: 219 YVQAV----EEFQSCLNLQEQYLEA----HDRLLAETHYQLGLAYGYNSQYDEAVAQFSK 270
+ V E+ +N + Q L+A H RLL SQY++ + + +
Sbjct: 700 KAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKN-----------QSQYEKQLKKLQQ 748
Query: 271 SIEVIENRMAVLNEQVKE----AEGSSAEYKKEIEELKE 305
+ ++ L +Q+KE A + + +EI +LK+
Sbjct: 749 DVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKK 787
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/241 (21%), Positives = 114/241 (47%), Gaps = 39/241 (16%)
Query: 121 EKTEDESLVENNDNIDETEGSEED----DKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176
EK + +S+ DN D + +E+ ++EN++ E + V +++ +E EEEE ++
Sbjct: 552 EKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDI 611
Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCL-NLQEQ 235
+ + D + E+ E Y A E++++ + + +E Q L L++Q
Sbjct: 612 D-GGESSDESD-----SESDEKANYQADLANITCEIAIK-QKLIDELENSQKRLQTLKKQ 664
Query: 236 YLEAHDRL---LAETHYQ-------LGLAYGYNSQYDEAV-AQFSKSIEVIENRMAVLNE 284
Y E L + +T + LG Y+ + + V +++ K ++ + + L
Sbjct: 665 YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQA 724
Query: 285 QVKEAE---GSSAEYKKEIEELKE-----------LLPEIREKIEDAK--ESQRSGNVAE 328
KE + ++Y+K++++L++ L+ +++E+ E A+ ES+R+ +A+
Sbjct: 725 AQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ 784
Query: 329 L 329
L
Sbjct: 785 L 785
Score = 33.1 bits (74), Expect = 0.53
Identities = 34/193 (17%), Positives = 79/193 (40%), Gaps = 7/193 (3%)
Query: 258 NSQYDEAVAQFSKSIEVIENRMAVL-NEQVKEAEGSSAEYKKEIEELKELLPEIREKIED 316
N+ + ++++ + +R+ L ++Q + E EE+ ++ ++IED
Sbjct: 432 NNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGN---EEISNMIHSYIKEIED 488
Query: 317 AKESQRSGNVAELALKATLVESSTSG-FTPGGGGSSVSMIASRKPTDGASSSNCVTDISH 375
+ L+ L ++ + G S ++++S K T D+
Sbjct: 489 LRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL-AKKDLEK 547
Query: 376 LVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENME-EEAENQAESRAAV 434
L RK+++ ++ K+D QE + G + + EV E+ E + E++ E
Sbjct: 548 LKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEE 607
Query: 435 EGTVEAGATVEST 447
E ++ G + + +
Sbjct: 608 EDDIDGGESSDES 620
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 47.8 bits (112), Expect = 2e-05
Identities = 57/243 (23%), Positives = 102/243 (41%), Gaps = 40/243 (16%)
Query: 100 RMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDD--KENDKTEEMPND 157
R E G G G EEEEGE+ E+ EG ++DD +E + E+
Sbjct: 383 RREGGGSGG---GGEEEEEEGEEGEE-------------EGDDKDDYWREQQEKLEIEKR 426
Query: 158 SVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 217
+++E+ SL E+ + E M DL R+E A++ A+ ++ V +
Sbjct: 427 AIVEDHSLVAEEKMRLLK-EKEKKMEDL------RREKDAAEMLGAKIKAMESKLLVGGK 479
Query: 218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277
N V E Q L + Q + R E Q+ DE + ++ ++
Sbjct: 480 NIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM-------ESRDEETLELKETYSSLQQ 532
Query: 278 RMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGN--VAELALKATL 335
+ + +++K+ K EI +L+E E I++ +E +++ N EL LK +
Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQE------EHIKERQELEQTQNELTRELKLKHLI 586
Query: 336 VES 338
+E+
Sbjct: 587 IEN 589
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 47.0 bits (110), Expect = 4e-05
Identities = 56/228 (24%), Positives = 100/228 (43%), Gaps = 33/228 (14%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175
E E EK E + I+ETE + ++ND + N E+K +E EEE+
Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK--EDKEKEEEEEEKPKR 200
Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVE----SENYVQAVEEFQSCLN 231
+ + ++ + ++T E+Q LK G++S E E Q +E
Sbjct: 201 GSIGENQVE----VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256
Query: 232 LQEQYLEAHD----RLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEV--------IENRM 279
++E+ E + RL AE ++ ++ D+ +A IE E R
Sbjct: 257 MEEEDKERAEAERARLEAEERERI------KAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 280 AVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED-----AKESQR 322
A E+++E E +AE ++ I+E ++ E R++I++ A+E QR
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/242 (22%), Positives = 101/242 (41%), Gaps = 16/242 (6%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
N E EEEE EK + S+ EN + E + E +E + N + + QE
Sbjct: 183 NKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET-VVMSLKNGQISSEEPKQE 241
Query: 168 NEEE----EIGNLE-LAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGE--VSVESENYV 220
E E EI + E + + + A+ R E +E + A+ K+ + +E+E
Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301
Query: 221 QAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMA 280
A E + +E+ E R AE ++ + ++ A+ + I+ E R A
Sbjct: 302 AAQERERREAEERERMREEEKR-AAEERQRI-------KEEEKRAAEERQRIKEEEKRAA 353
Query: 281 VLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
+++KE E +AE ++ +E ++ E+ + + ++ + E +K VE
Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI 413
Query: 341 SG 342
G
Sbjct: 414 EG 415
Score = 37.0 bits (84), Expect = 0.036
Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 18/228 (7%)
Query: 116 EEEEGEKTEDES----LVENNDNIDETE--GSEEDDKENDK--TEEMPNDSVLENKSLQE 167
EEEE K E++ L E + ET+ G + + K K E+ + L+ L++
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227
EE+ ++ + L K FK++E K+ ++ K E E ++++ + F
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI------KKDKEPKEEVKSFMDRKKGFT 489
Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQF--SKSIEVIENRMA-VLNE 284
+ +++ + T + G +++ E Q K +E + R +E
Sbjct: 490 EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 549
Query: 285 QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALK 332
+ ++ + E E+EELK+ E R K+ + +E +R A+ L+
Sbjct: 550 EFEKLKQKQQEAALELEELKKKREE-RRKVLEEEEQRRKQEEADRKLR 596
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 45.8 bits (107), Expect = 8e-05
Identities = 92/411 (22%), Positives = 161/411 (39%), Gaps = 38/411 (9%)
Query: 50 GQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNA 109
G ++GD+ A + + QE L + E EA S E +E L
Sbjct: 618 GHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID-LNYK 676
Query: 110 LEGVH--VEEEEGE-KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ 166
L+ + +E+E E K L + + +I+E + + E EE EN+ +Q
Sbjct: 677 LKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQ 736
Query: 167 ENEEEEIGNLELAWDMLDLAKIIFKRQ----ETKEAQLYAAQAHLKLGEVSVESENYVQA 222
++ + +++L L + ++ E K L Q K + +++E QA
Sbjct: 737 IEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNK--RLLLQNELKTQA 794
Query: 223 VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVL 282
E + L++Q + + LL + +AQ +K E +M L
Sbjct: 795 FEA-DNLKGLEKQMKQEINTLLEAKRL-----------LEFELAQLTKQYRGNEGQMREL 842
Query: 283 NEQVKEAEGSSAEYKKEIEELKELLPEIREK-IEDAKESQRSGNVAE-LALKATLVESST 340
+Q++ + S YK +++ELKE EI EK E+ K+ Q N E LA + L E+
Sbjct: 843 QDQLEAEQYFSTLYKTQVKELKE---EIEEKNRENLKKIQELQNEKETLATQLDLAETKA 899
Query: 341 SGFTPGGGGSSVSMIASRKPTDGASSSNC--VTDISHLVRKKRKPEEESPRKDDAKKAKQ 398
G + + A+S N +TD H V R E S D + ++
Sbjct: 900 ESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTV--SRLEEANSMLTKDIEILRR 957
Query: 399 EPEVNGGSGDAVPSGNEVSENMEEEAENQAES-RAAVEGTVEAGATVESTA 448
E E + + E + E E + + +AA E + T+++ A
Sbjct: 958 ENE------ELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQA 1002
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 45.8 bits (107), Expect = 8e-05
Identities = 66/318 (20%), Positives = 127/318 (39%), Gaps = 56/318 (17%)
Query: 129 VENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKI 188
V+N NI E + E +++ N+ V EN +LQ+ EE G L + L K+
Sbjct: 634 VKNQQNIKEERERMRANLEELRSQH--NEKVEENSTLQQRLEESEGELRKNLEELFQVKM 691
Query: 189 IFKRQETK----EAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYL--EAHDR 242
++ +T+ + QL L + S + E E Q+ +LQ+ + E +
Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751
Query: 243 LLAETHYQLGLAYG---------------YNSQYD-------EAVAQFSKSIEVI----- 275
LL + +L G QYD E+V + +K++EV+
Sbjct: 752 LLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSN 811
Query: 276 ---------ENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNV 326
E R+ +L E+ ++ +G S E ++ + +L+ + +++ AKE+ +
Sbjct: 812 TSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEG 871
Query: 327 AELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDG---ASSSNCVTDISHLVRKKRKP 383
L+ LV + +++R+ + A+ N + K
Sbjct: 872 EIRQLEEALVHARK---------EEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKL 922
Query: 384 EEESPRKDDAKKAKQEPE 401
+EES +K+ ++ K E E
Sbjct: 923 KEESEQKEQLRRLKNEME 940
Score = 41.2 bits (95), Expect = 0.002
Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 22/217 (10%)
Query: 117 EEEGEKTE----DESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEE 172
E E +TE + L E +D +D + SE+ +K E + L++ + + E+E+
Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751
Query: 173 IGNLELAWDMLDLAKIIFKRQ---ETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229
+ L L K K + +E Q +L + E + VE S
Sbjct: 752 L--LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASR 809
Query: 230 LNLQEQ---YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQV 286
N EQ E +LL E + +L G + + + VAQ + IE ++ A E +
Sbjct: 810 SNTSEQDQAGTEMRVKLLQEENEKL---QGRSEELERRVAQLQRQIEDLKGDEAKAKETL 866
Query: 287 KEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323
K+ EG EI +L+E L R++ ++A ++R+
Sbjct: 867 KKYEG-------EIRQLEEALVHARKEEKEAVSARRA 896
Score = 35.4 bits (80), Expect = 0.11
Identities = 44/203 (21%), Positives = 85/203 (41%), Gaps = 17/203 (8%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175
E+E+ + + L + E S D+E DK +E + E ++L+E+ EE N
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSH--DQEMDKLKEQYD---AELQALRESVEEATKN 802
Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQ 235
+E ++ R T E + +KL + E+E EE + + ++
Sbjct: 803 VE----------VLASRSNTSEQDQAGTEMRVKL--LQEENEKLQGRSEELERRVAQLQR 850
Query: 236 YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE 295
+E A+ L G Q +EA+ K + + L +++ A+G+ ++
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910
Query: 296 YKKEIEELKELLPEIREKIEDAK 318
+E ++L E L E E+ E +
Sbjct: 911 TTQEQKQLSEKLKEESEQKEQLR 933
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/209 (19%), Positives = 93/209 (44%), Gaps = 18/209 (8%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGS--EEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173
E+EE + ++E + E + + E E+++K + E+M + + + EEE+I
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372
Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233
E KRQE +EA+++ + ++ E + + + ++E + + Q
Sbjct: 373 REQE-------------KRQE-QEAKMWRQEEKIREQEEKIREQE--EMMQEQEEKMGEQ 416
Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSS 293
E+ + + + E ++ + ++ + + + I E M E++ E EG
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 294 AEYKKEIEELKELLPEIREKIEDAKESQR 322
E + +++E +E + EKI + ++ R
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/205 (17%), Positives = 91/205 (44%), Gaps = 9/205 (4%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGS-EEDDKENDKTEEMPNDSVLENKSLQENEEEEIG 174
E+EE + ++E + E + I E E E +K ++ E+ + + + ++ +E ++
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386
Query: 175 NLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQE 234
E KI + ++ +E + + K+GE + + ++E + + QE
Sbjct: 387 RQE--------EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 235 QYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSA 294
+ + ++ + E ++ + +E + + + E +M E+++ E
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 295 EYKKEIEELKELLPEIREKIEDAKE 319
E +K+I E +E + E E +++ +E
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEE 523
Score = 36.6 bits (83), Expect = 0.048
Identities = 37/223 (16%), Positives = 94/223 (42%), Gaps = 27/223 (12%)
Query: 126 ESLVENNDNIDETEGSEEDD--KENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDML 183
++ VE N+ + +E+ ++ +K +E + + ++E EE+ E+ W+
Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329
Query: 184 DLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF----------------Q 227
+ + + KE ++ + + E E E Q E+ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287
+ QE+ + + ++ E ++G + +E + + + ++ E +M E+++
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMG-------EQEEKMWEQEEEMQEQEEKMRRQEEKIR 442
Query: 288 EAEGSSAEYKKEIEELKELLPEIREKI--EDAKESQRSGNVAE 328
E E E +++I E +E++ E EK+ ++ K ++ + E
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Score = 34.7 bits (78), Expect = 0.18
Identities = 34/198 (17%), Positives = 84/198 (42%), Gaps = 12/198 (6%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEG--SEEDDKENDKTEEM--PNDSVLENKSLQENEEE 171
E+E ++E + E + I E E E+++K ++ E+M + + E + +EE
Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 172 EIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLN 231
+I E KI + ++ +E + + K+GE + ++E + +
Sbjct: 440 KIREQE--------KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 232 LQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEG 291
QE+ + ++ + E ++ + +E + + + + E +M E+++ E
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 292 SSAEYKKEIEELKELLPE 309
E + + + +E + E
Sbjct: 552 KMREQEVRLRQQEEKMQE 569
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 45.4 bits (106), Expect = 1e-04
Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170
EG E+E+ E E+E E +D ++ EG E+DD+ +++ EE D E++ E+EE
Sbjct: 173 EGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDE--EDEDEDEDEE 230
Query: 171 EEIG 174
EE G
Sbjct: 231 EEEG 234
Score = 32.0 bits (71), Expect = 1.2
Identities = 13/55 (23%), Positives = 30/55 (54%)
Query: 119 EGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173
+G ED+ +++ +D + EED++ D+ +E D E +++E+E++
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/239 (18%), Positives = 98/239 (41%), Gaps = 17/239 (7%)
Query: 100 RMENGVLGNALEGVHVEEEE--GEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPND 157
R + G +G EG E+EE GE+ E E E + +++++ ++ E++
Sbjct: 188 REQEGQMGEQ-EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 158 SVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 217
K ++ ++E E M + + + K++E E + + ++ E +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAE--------------THYQLGLAYGYNSQYDE 263
+ + E + + QE+ + + + E Q+G + +E
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Query: 264 AVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322
V + + + E +M EQ+++ E E K+++ E KE + E E++ + KE R
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/209 (17%), Positives = 87/209 (41%), Gaps = 12/209 (5%)
Query: 115 VEEEEGEKTEDESLV-ENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173
V E+EG+ E E V E + E EG + + + +E V E + +E ++
Sbjct: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---GQVREQEGQVREQEGQV 124
Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233
E ++ + + +E + + ++ E + V E + + Q
Sbjct: 125 REQE--------GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176
Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSS 293
E + + + E Q+G G + +E + + + ++ E +M EQ+++ E
Sbjct: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQM 236
Query: 294 AEYKKEIEELKELLPEIREKIEDAKESQR 322
E ++++++ +E + + E++ +E R
Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Score = 28.9 bits (63), Expect = 9.9
Identities = 54/278 (19%), Positives = 103/278 (37%), Gaps = 25/278 (8%)
Query: 160 LENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENY 219
L+ K+ + EE ++ E + L + ++ K + K Q + G+V E E
Sbjct: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR-EQEGQ 67
Query: 220 VQA----VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVI 275
V+ V E + + QE + + + E Q+ G + + V + +
Sbjct: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127
Query: 276 ENRMAVLNEQVKEAEGSSAEYKKEIEE----LKELLPEIREKIEDAKESQRSGNVAELAL 331
E ++ QV+E EG E + ++ E ++E ++RE+ +E + G V E
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEG 185
Query: 332 KATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKD 391
+ E G G + ++ G ++ +EE RK
Sbjct: 186 QVREQE--------GQMGEQEGQMGEQEEQMGEQEEQMQKQ-----EEQMGEQEEQMRKQ 232
Query: 392 DAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAE 429
+ + +QE +V + V E EE+ Q E
Sbjct: 233 EEQMGEQEEQVQ-KQEEQVQKQEEQMRKQEEQMREQEE 269
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/235 (22%), Positives = 98/235 (41%), Gaps = 32/235 (13%)
Query: 95 LLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDETEGS-----EEDDKEN 148
L EL + E+ +L E + LVE D E + EE +K
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 149 DKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLK 208
D++E V+E+++ ++ E+ EI ++L KEA+ A A K
Sbjct: 121 DESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHIAEDADRK 161
Query: 209 LGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQF 268
EV+ + + +S L E+ E + AE +L + ++
Sbjct: 162 YEEVA-------RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY 214
Query: 269 SKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323
S+ + E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE S
Sbjct: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269
>gi|28460688 taxilin [Homo sapiens]
Length = 546
Score = 45.1 bits (105), Expect = 1e-04
Identities = 71/308 (23%), Positives = 131/308 (42%), Gaps = 55/308 (17%)
Query: 42 EAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARM 101
E KK GLG++ ++ ++ +E + L KKY E E + + ++L +
Sbjct: 161 EKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNS-----QKQMKLLQK 215
Query: 102 ENGVLGNALEGVHVEEEEG--EKTEDESL---VENNDNIDETEGSEEDDKENDKTEEMP- 155
+ L + + E + +++ ESL ++ ++ + EG + +E +K +E+
Sbjct: 216 KQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTS 275
Query: 156 ------NDSVL--------------ENKSLQENEEEEIGNLELAWDMLDLAKIIFK---- 191
ND L EN L E ++ I EL + +D +FK
Sbjct: 276 HFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK---VFKHKDL 332
Query: 192 RQETKEAQLYAAQAHLKLGEVSVESEN---YVQAVEEFQSCLNLQEQYLEAHDRLLAETH 248
+Q+ +A+L AQ LK E + E +AVE + C +++Q ETH
Sbjct: 333 QQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQ----------ETH 382
Query: 249 YQLGLAYGYNSQYDEAVAQFSKSIEV---IENRMAVLNEQVKEAEGSSAEYKKEIEELKE 305
+ LA Y +++E SKS EV + M + +++K+ E + Y+ E +
Sbjct: 383 LKQQLAL-YTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNK 441
Query: 306 LLPEIREK 313
L E+ E+
Sbjct: 442 ALLEMAEE 449
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/229 (24%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 118 EEGEKTEDESLVENNDNIDETEGSEEDDKEND--KTEEMPNDSVL---------ENKSLQ 166
+E E+ + +++ E + I +TE + K+ D EE+ D ++ E K LQ
Sbjct: 626 QEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ 685
Query: 167 E---NEEEEIGNLELA--WDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221
E N+E++I E A + + L K ++ Q K+ L+ Q ++ + +E E +
Sbjct: 686 ERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE---K 742
Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSI-EVIENRMA 280
A+E N + LE D + + L S Y+E + QF + + E NR+
Sbjct: 743 ALEH----KNRMSRMLEDRDLFV------MRLKAARQSVYEEKLKQFEERLAEERHNRLE 792
Query: 281 VLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAEL 329
Q KE + +KE EE + ++ ++ E+ + ++R+ EL
Sbjct: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/238 (23%), Positives = 101/238 (42%), Gaps = 38/238 (15%)
Query: 95 LLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDETEGS-----EEDDKEN 148
L EL + E+ +L E + LVE D E + EE +K
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 149 DKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLK 208
D++E V+E+++ ++ E+ EI ++L KEA+ A A K
Sbjct: 121 DESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHIAEDADRK 161
Query: 209 LGEVS---VESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAV 265
EV+ V E+ ++ EE Q + LE R++ +T L A SQ ++
Sbjct: 162 YEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY 221
Query: 266 AQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323
E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE S
Sbjct: 222 ----------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/182 (22%), Positives = 82/182 (45%), Gaps = 26/182 (14%)
Query: 142 EEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY 201
EE +K D++E V+E+++ ++ E+ EI ++L KEA+
Sbjct: 114 EEAEKAADESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHI 154
Query: 202 AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY 261
A A K EV+ + + +S L E+ E + AE +L
Sbjct: 155 AEDADRKYEEVA-------RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 207
Query: 262 DEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQ 321
+ ++S+ + E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE
Sbjct: 208 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEEN 267
Query: 322 RS 323
S
Sbjct: 268 LS 269
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/213 (18%), Positives = 90/213 (42%), Gaps = 15/213 (7%)
Query: 129 VENNDNIDETEGSEEDDKE-NDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAK 187
++ + +D E +E D K D+++++ ++ V K L+ E+E E D + +
Sbjct: 13 LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE 72
Query: 188 IIFKRQETKEAQLYAAQAHLKLGEVSVES------------ENYVQAVEEFQSCLNLQEQ 235
+ K+ EA + + ++L E ++ E +A +E + + + E
Sbjct: 73 LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIES 132
Query: 236 YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE 295
+ + + QL A D + ++ + +IE+ + E+ + +EG AE
Sbjct: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAE 192
Query: 296 YKKEIEELKELLPEIREKIEDAKESQRSGNVAE 328
++E++ + L + + E K SQ+ E
Sbjct: 193 LEEELKTVTNNLKSLEAQAE--KYSQKEDRYEE 223
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 44.7 bits (104), Expect = 2e-04
Identities = 77/354 (21%), Positives = 136/354 (38%), Gaps = 27/354 (7%)
Query: 111 EGVHVEEEEGE---KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
EG+ E EGE ++E E + E EG + + E+ + E ++ +
Sbjct: 1833 EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA--------Q 1884
Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQ--LYAAQAHLKLGEVSVESE-----NYV 220
E E++ E W++ ++ + KEAQ + +A GE ESE
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 221 QAVEEFQSCLNLQEQYL---EAHDRLLAETHYQLGLAYGYNSQYDEAVAQ-FSKSIEV-- 274
+A +E + + + + EA + E+ L +Q E AQ S+ +E
Sbjct: 1945 EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE 2004
Query: 275 IENRMAVLNEQVK-EAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333
E M E+ + E++G A+ K E EE +E+ E ++ DA+ E +A
Sbjct: 2005 AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064
Query: 334 TLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKD-D 392
E S + A + S V ++ E+P + +
Sbjct: 2065 QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 393 AKKAKQEPEVNGGSGDAVPSGNEV-SENMEEEAENQAESRAAVEGTVEAGATVE 445
A+ + E G+A P V +++ E EA+ ++E A E EA +E
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Score = 31.6 bits (70), Expect = 1.5
Identities = 72/340 (21%), Positives = 120/340 (35%), Gaps = 55/340 (16%)
Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169
+E EEE ++ED +E E EG + + E+ + E E + +E
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEG----EMQEAEEEA 2016
Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENY--VQAVEEFQ 227
+ E +E + E +EAQ + G+ ES+ +A EE Q
Sbjct: 2017 QPESDGVEAQ-----------PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065
Query: 228 SCL-NLQEQYLEAH------DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMA 280
+QE EAH D AE Q + G + E AQ ++ IE E
Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQ-PESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 281 VLNE----QVKEAEGSSAEYKKEIE---------------ELKELLPEIREKIE--DAKE 319
E + EAEG + + +E E +E E + ++E +A E
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 320 SQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRK 379
++ ++A E G A +P +G +
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEP-EGVETPE--------AEG 2235
Query: 380 KRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSEN 419
+ +PE E + + K + Q +G S +A S + V E+
Sbjct: 2236 EAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED 2275
Score = 30.0 bits (66), Expect = 4.4
Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 18/100 (18%)
Query: 134 NIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE--------EEIGNLELAWDMLDL 185
N DE E E+ + + E++ ++V E L+E +E EE LE L
Sbjct: 1272 NEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGL 1331
Query: 186 AKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE 225
+ + +ETKE + GE E E ++ +EE
Sbjct: 1332 QEEGVQLEETKETE----------GEGQQEEEAQLEEIEE 1361
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/239 (19%), Positives = 101/239 (42%), Gaps = 32/239 (13%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
N EG VEE++ E+E+L + + E E ++E E+ + + ++K
Sbjct: 1736 NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK---EKLAQHKEKMP 1792
Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF- 226
EEE +G KR++ E ++ AQ + E ++ ++EE
Sbjct: 1793 EEEERLGR---------------KREQLIEKKMKLAQ----------KRERWINSMEELT 1827
Query: 227 -QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQ 285
+ Q++ L + LA+ +L E + K + ++N++ + N+
Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKI 1887
Query: 286 VKEAEGSSAEYKKEIEELKELLPEIREKIEDAKES--QRSGNVAELALKATLVESSTSG 342
+ + E + K+ + + KE L E +K+ ++S ++ +A+ +K L ++ G
Sbjct: 1888 LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946
Score = 38.9 bits (89), Expect = 0.010
Identities = 50/208 (24%), Positives = 92/208 (44%), Gaps = 12/208 (5%)
Query: 115 VEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEE-EI 173
VE EE E ESL++ + + EE+++E + EE + V E + ++ EEE E
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEE--EEREEEEVREEEEERKEEEEGEE 2277
Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233
+E + K K++E +E + + + E E+E+ EE +SC +L+
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE--EETESLSDEEEEEESC-SLE 2334
Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN---RMAVLNEQVKEAE 290
E+ + L E ++L + + E V + + + R+ VL +K+
Sbjct: 2335 EEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLM 2394
Query: 291 GSSAEYKKEIEELKELLPEIREKIEDAK 318
++ E K E+ +PE + ED K
Sbjct: 2395 STALEMK---EKTPVPVPEKQISWEDKK 2419
Score = 34.7 bits (78), Expect = 0.18
Identities = 51/238 (21%), Positives = 99/238 (41%), Gaps = 55/238 (23%)
Query: 117 EEEGEKT---EDESLVENNDNIDETEGSEEDDKENDKTEEMPN--DSVLENKSLQENEEE 171
+EE EK E+E L + + + E ++DK+ K EE +++L +KS ++ ++
Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKL-KWEEWKQVWENMLSSKSKEQQYKD 1540
Query: 172 EIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHL----KLGEVSVESENYVQAVEEFQ 227
E + + L + + + E KE Q+ Q H+ K + + + + +
Sbjct: 1541 E--------EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287
L +E+ L +R LA+ +L AY +Q D +AQ
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQ-------------------- 1632
Query: 288 EAEGSSAEYKKEIEELKELLPEIREKI----------------EDAKESQRSGNVAEL 329
AEG A+ ++ + + E L + EK+ E+ K +++ G +AE+
Sbjct: 1633 -AEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEV 1689
Score = 33.1 bits (74), Expect = 0.53
Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 26/203 (12%)
Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176
E+ E T+DE + + +KE TEE + ++ + ++EEE G +
Sbjct: 2127 EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEE--GGI 2184
Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQY 236
E + L + KR+E K E + V+E +S +E +
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDK--------------PKEKFSSQVDEVES----EEHF 2226
Query: 237 LEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEY 296
E + LL E Q L+ + +E + + + E E+ +E EG +
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE------ERKEEEEGEEKQV 2280
Query: 297 KKEIEELKELLPEIREKIEDAKE 319
+KE EE K+ E +++ KE
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 32.3 bits (72), Expect = 0.90
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 15/100 (15%)
Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKS------ 164
E V EEE E+ E+E E +E E ++ KE K E + V E K
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEE-KKKKKKEKKKEEVQEKEEVFEEKEEIMSEE 2316
Query: 165 -----LQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQ 199
E EEEE +LE + +D K I K+++ + Q
Sbjct: 2317 ETESLSDEEEEEESCSLE---EEVDREKEILKKEKQFKLQ 2353
Score = 32.0 bits (71), Expect = 1.2
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 24/227 (10%)
Query: 111 EGVHVEEE---EGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
E V +EEE EGE+ E + + E +I E ++ + E+ E K QE
Sbjct: 1542 EEVTLEEEVSREGEEKEQQ-VTEEQRHIQEEHKWARIHRKRARAEKKRAQE--ERKLAQE 1598
Query: 168 NEEEEIGNLELAWDMLDLA----KIIFKRQETKEAQLYAAQAHLKLGE----VSVESENY 219
E+ +LA + LA KI +E +A+ AQ L + +S E+E
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 220 VQA----VEEFQSCLNLQEQYLEAHDRL------LAETHYQLGLAYGYNSQYDEAVAQFS 269
Q ++++ +E+ + +L LA+ +L ++ +AQ
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED 316
+ +E ++ E++ + EG E KK++ E +E L REK+ +
Sbjct: 1719 EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 44.3 bits (103), Expect = 2e-04
Identities = 46/185 (24%), Positives = 85/185 (45%), Gaps = 32/185 (17%)
Query: 142 EEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY 201
EE +K D++E V+E+++ ++ E+ EI ++L KEA+
Sbjct: 114 EEAEKAADESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHI 154
Query: 202 AAQAHLKLGEVS---VESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYN 258
A A K EV+ V E+ ++ EE Q + LE R++ +T L A
Sbjct: 155 AEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKY 214
Query: 259 SQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAK 318
SQ ++ E + VL++++KEAE + ++ + +L++ + ++ EK+ AK
Sbjct: 215 SQKEDRY----------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAK 264
Query: 319 ESQRS 323
E S
Sbjct: 265 EENLS 269
Score = 35.0 bits (79), Expect = 0.14
Identities = 40/214 (18%), Positives = 89/214 (41%), Gaps = 26/214 (12%)
Query: 129 VENNDNIDETEGSEEDDKE-NDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAK 187
++ + +D E +E D K D+++++ ++ V K L+ E+E E D + +
Sbjct: 13 LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE 72
Query: 188 IIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAET 247
+ K+ EA + + ++L E ++ +A E + L E+ +A D
Sbjct: 73 LAEKKATDAEADVASLNRRIQLVEEELD-----RAQERLATALQKLEEAEKAAD------ 121
Query: 248 HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELL 307
+ + + + E +M + Q+KEA+ + + ++ EE+ L
Sbjct: 122 ------------ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169
Query: 308 PEIREKIEDAKESQR--SGNVAELALKATLVESS 339
I +E A+E G V +L + +++ +
Sbjct: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQT 203
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 44.3 bits (103), Expect = 2e-04
Identities = 55/234 (23%), Positives = 100/234 (42%), Gaps = 42/234 (17%)
Query: 115 VEEEEG----EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170
V++ EG + ++E L+E + E G E+ + E M ND +++L +N E
Sbjct: 487 VQDNEGLSRLNREQEERLLEL-ERAAELWG-EQAEARRQILETMQNDRTTISRALSQNRE 544
Query: 171 --EEIGNLE-----LAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAV 223
E++ L+ L + +++ + Q K + KLGE+ + + V
Sbjct: 545 LKEQLAELQSGFVKLTNENMEITSALQSEQHVKR------ELGKKLGELQEKLSELKETV 598
Query: 224 E----EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRM 279
E E QS ++QYL G+ QY A Q + EV+ N++
Sbjct: 599 ELKSQEAQSLQQQRDQYL------------------GHLQQYVAAYQQLTSEKEVLHNQL 640
Query: 280 AVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333
+ + V + + A+ K E ++ L E +E++E A + Q A+L+L A
Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQ-QNQQLRAQLSLMA 693
Score = 38.1 bits (87), Expect = 0.016
Identities = 78/333 (23%), Positives = 138/333 (41%), Gaps = 53/333 (15%)
Query: 92 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDE-SLVENNDNIDETEGSEEDDKENDK 150
GK++ E+AR E L E + ++ ++ + SL+ + D + EE+D+E ++
Sbjct: 657 GKAVAEMARQE---LQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEE 713
Query: 151 TEEM----PNDSVLE------------NKSLQENEEEEI---GNL-ELAWDMLDLAKIIF 190
E + P S+ E N ++ EEE+ G L E LA ++
Sbjct: 714 EEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLA 773
Query: 191 KRQETKEAQLYAAQAHLKLGE-VSVESENYVQ-AVEEFQS-CLNLQEQYLEAHDRLLAET 247
Q+ EA AA A G+ V E+ +Q A+E+ QS + L ++ + +R+
Sbjct: 774 SAQKEPEA---AAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELE 830
Query: 248 HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELL 307
H + L+ G E +A + +++ AVL E+ +E E + ++ EE+K L
Sbjct: 831 HRCIQLS-GETDTIGEYIALY-------QSQRAVLKERHREKEEYISRLAQDKEEMKVKL 882
Query: 308 PEIREKIEDAKESQRSGNVAELALKATLVESSTSG---------FTPGGGGSSVSMIASR 358
E++E + + + LA + TSG G VS+ S
Sbjct: 883 LELQELVLRLVGDRNEWHGRFLAAAQNPADEPTSGAPAPQELGAANQQGDLCEVSLAGSV 942
Query: 359 KPTDGASSSNCVTD------ISHLVRKKRKPEE 385
+P G + D I L+R+ + P E
Sbjct: 943 EPAQGEAREGSPRDNPTAQQIMQLLREMQNPRE 975
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/237 (20%), Positives = 102/237 (43%), Gaps = 19/237 (8%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKEN-DKTEEMPNDSVLENKSLQ 166
N+L+ EEEE K ++ ++ + +T+ +DD + EE + + ++L
Sbjct: 1346 NSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS 1405
Query: 167 ENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF 226
+ EE+ LA+D L+ K + QE + + + + + + Q + E
Sbjct: 1406 QRLEEKA----LAYDKLEKTKNRLQ-QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEE 1460
Query: 227 QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVA----------QFSKSIEVIE 276
+S + +Y E DR AE + A +EA+ Q +E +
Sbjct: 1461 KS---ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 277 NRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333
+ + + V E E S ++++EE++ L E+ ++++ ++++ V A+KA
Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKA 1574
Score = 38.9 bits (89), Expect = 0.010
Identities = 45/244 (18%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEE--DDKENDKTEEMPNDS-----VLENK----- 163
E E+ K+ + +++ + + +E + + + ++ +E+ N + +L+ K
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736
Query: 164 ---SLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYV 220
L+E EEE N+EL D + + +T A+L A ++ + +S+N
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTL---QVDTLNAELAAERS------AAQKSDNAR 1787
Query: 221 QAVEEFQSCLNLQEQYLEAHDR-----LLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVI 275
Q +E L + Q LE + ++ ++G Q + A +K +
Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847
Query: 276 ENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATL 335
E ++ + QV++ + +YK+++E+ + +++ ++E+A+E N + L+ L
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 336 VESS 339
+++
Sbjct: 1908 DDAT 1911
Score = 36.2 bits (82), Expect = 0.062
Identities = 47/233 (20%), Positives = 91/233 (39%), Gaps = 21/233 (9%)
Query: 106 LGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSL 165
L ALE +EE E+ + + D + + ++ E +K++ V E ++
Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 166 QENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE 225
E E+E+ E A L++ K Q ++ Q Q EE
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN------------------EE 1589
Query: 226 FQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQ 285
+ L Q + LEA L + Q LA + + + IE + +Q
Sbjct: 1590 KKRLLIKQVRELEAE---LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646
Query: 286 VKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVES 338
+++ + +Y++E+EE + EI + +++++ +S L L+ L S
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASS 1699
Score = 33.1 bits (74), Expect = 0.53
Identities = 69/352 (19%), Positives = 135/352 (38%), Gaps = 40/352 (11%)
Query: 93 KSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTE 152
K LE E L+ V E E K D + E + + +EG + +K
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKV--SEGDRLRVELAEKAS 1283
Query: 153 EMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQET-KEAQLYAAQAHLKLGE 211
++ N+ L+N S E E+ G ++ A D L + QE +E ++ +
Sbjct: 1284 KLQNE--LDNVSTLLEEAEKKG-IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Query: 212 VSVESENYV-QAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSK 270
+ E + Q EE ++ NL++Q L +L A+T ++ G +EA + K
Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL-ADTKKKVDDDLGTIESLEEAKKKLLK 1399
Query: 271 SIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGN---VA 327
E + R+ + E + ++E+++L L R+ + ++ Q+ +
Sbjct: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459
Query: 328 ELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEES 387
E ++ A E R + ++ + + + +EE
Sbjct: 1460 EKSISARYAEE-----------------RDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 388 PRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVE 439
R++ +A E D + S ++V +N+ E +S+ A+E VE
Sbjct: 1503 ERQNKQLRADME--------DLMSSKDDVGKNVHE----LEKSKRALEQQVE 1542
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/87 (21%), Positives = 40/87 (45%)
Query: 233 QEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGS 292
QE+ L+A D L + + G + + Q + ++ ++ E EAE
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 293 SAEYKKEIEELKELLPEIREKIEDAKE 319
A + +EL+E+L ++ ++E+ +E
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEE 936
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/218 (19%), Positives = 97/218 (44%), Gaps = 27/218 (12%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEG--SEEDDKENDKTEEMPNDSVLENKSL 165
+AL+ ++ +E + L E + ID+ G SE+ DK ++ +++ N + + +
Sbjct: 1763 DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI 1822
Query: 166 QENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAV-- 223
QE + E + L D+ + K + + ++ K+ L L ++ +E+ N Q +
Sbjct: 1823 QELKANEHQLITLKKDVNETQKKVSEMEQLKKQ---IKDQSLTLSKLEIENLNLAQKLHE 1879
Query: 224 --EEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281
EE +S + ++ + L E Q +S++ + R
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERD------------------QLKESLQETKARDLE 1921
Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319
+ +++K A S E+K+ +++L+E + E +I D ++
Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQK 1959
Score = 38.1 bits (87), Expect = 0.016
Identities = 48/236 (20%), Positives = 97/236 (41%), Gaps = 30/236 (12%)
Query: 114 HVEEE-EGEKTEDESLVENNDNI-----DETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
H++E+ E +K E++ N + + E KE D + +E L+E
Sbjct: 1648 HLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKE 1707
Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227
N E I R K+ +L HLK + +++ + + E+
Sbjct: 1708 NLRETI-----------------TRDLEKQEELKIVHMHLKEHQETIDKLRGIVS-EKTN 1749
Query: 228 SCLNLQEQYLEAHDRLLAET---HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNE 284
N+Q+ ++D L A+ +L +A+ + + E + K ++ + L+
Sbjct: 1750 EISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI---DKLRGIVSEKTDKLSN 1806
Query: 285 QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
K+ E S+A+ +++I+ELK ++ +D E+Q+ + E K +S T
Sbjct: 1807 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862
Score = 35.8 bits (81), Expect = 0.081
Identities = 38/231 (16%), Positives = 101/231 (43%), Gaps = 26/231 (11%)
Query: 116 EEEEGEKTEDESLVENNDNIDE--------TEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
+E + KT E+L +D + E + S+ +++ +E N++ +++
Sbjct: 1349 KERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQ 1408
Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227
+ ++ L + +ML L+K + ++H ++ V+ E ++ + E Q
Sbjct: 1409 FKPKDSALLRIEIEMLGLSKRL-------------QESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287
S + ++ ++ ET +L +A+ + +E + + ++ E ++ + +Q++
Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE 1515
Query: 288 EAEGSSAEYKKEIEELKEL-----LPEIREKIEDAKESQRSGNVAELALKA 333
+EI E +E + E++EK+ + K+ + + AL++
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQS 1566
Score = 35.4 bits (80), Expect = 0.11
Identities = 45/239 (18%), Positives = 100/239 (41%), Gaps = 19/239 (7%)
Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170
E + +E ++ + +++ N D ++ + E K++ +T + E S + E
Sbjct: 939 ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHME 998
Query: 171 EEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE----- 225
E G + + + I K+Q+ + A +K E+ + ++E
Sbjct: 999 ENTGETKDEFQQKMVG--IDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056
Query: 226 --FQSCLNLQEQY---LEAHDRLLAETHYQLGLAYGYNSQYDEAVAQ-----FSKSIEVI 275
+S + +EQ L+ + + E +L L + E VAQ K E+
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116
Query: 276 E--NRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALK 332
+R+A + E++KE E ++++ ++E + E+++KI + + + EL L+
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Score = 34.3 bits (77), Expect = 0.24
Identities = 42/226 (18%), Positives = 91/226 (40%), Gaps = 18/226 (7%)
Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176
E EG+ T+ + E N ++E E E+ + + +P++ K +Q+ EE L
Sbjct: 717 ELEGKITDLQK--ELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEE----L 770
Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHL--KLGEVSVESENYVQAVEEFQSCLNLQE 234
+ D +F KE+++ + +++ NY +EFQ+ L
Sbjct: 771 HIITSEKDK---LFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHM 827
Query: 235 QYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSA 294
+ + + +L E + + +F S+ ++ ++ ++++E
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKE----AQKFDSSLGALKTELSYKTQELQEKTREVQ 883
Query: 295 EYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340
E E+E+LKE ++ + + +R + L+ TL E T
Sbjct: 884 ERLNEMEQLKE---QLENRDSTLQTVEREKTLITEKLQQTLEEVKT 926
Score = 33.5 bits (75), Expect = 0.40
Identities = 51/247 (20%), Positives = 106/247 (42%), Gaps = 41/247 (16%)
Query: 114 HVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLE---------NKS 164
H+ E + E +S E + N+ E + +E ++ + P DS L +K
Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKD-NETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1429
Query: 165 LQENEEE------EIGNLELAWDML---------DLAKIIFKRQETKEAQLYAAQAHLKL 209
LQE+ +E E +L+ ++L ++ +I+ K ET+E +L A LK
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEE-ELKVAHCCLKE 1488
Query: 210 GEVSV--------ESENYVQAVEEFQSCLN------LQEQYLEAHDRLLAETHYQLGLAY 255
E ++ E E + +++ +N +QE Y E ++ + ++
Sbjct: 1489 QEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIY-EKEEQFNIKQISEVQEKV 1547
Query: 256 GYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315
Q+ E +++ IE++M L +++E++ KE EE+K + ++ + +
Sbjct: 1548 NELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607
Query: 316 DAKESQR 322
KE+ +
Sbjct: 1608 QLKENTK 1614
Score = 31.6 bits (70), Expect = 1.5
Identities = 32/189 (16%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175
E+ EK E E ++ +++DE E E K++ + + + S L+N + E+ N
Sbjct: 515 EQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLV----KHAEVYN 570
Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHL---KLGEVSVESENYVQAVEEFQSCLNL 232
+L ++ +++ KE Q+ Q ++ KL + ++ ++++E+ +
Sbjct: 571 QDLENELSSKVELL----REKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQ---- 622
Query: 233 QEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGS 292
+Q L + + + + N + E + + + + + +EN + + Q++ +
Sbjct: 623 MKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKM 682
Query: 293 SAEYKKEIE 301
+ +KE++
Sbjct: 683 QVDLEKELQ 691
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%)
Query: 212 VSVESENYVQAVEEFQSCLNLQEQYLEAHDRL----LAETHY---QLGLAYGYNSQYDEA 264
+ +E E Y + E + L ++ +E + + E+H Q+ ++ + Q E
Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 265 VAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSG 324
+ +K IE + L ++++AE + Y E+ ELK+LL E+++K++D+
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251
Query: 325 NVAELALKATLVESST 340
N LKA L E+ T
Sbjct: 1252 NEELNLLKAQLNETLT 1267
Score = 30.8 bits (68), Expect = 2.6
Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 155 PNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQL----YAAQAHL--- 207
P++ +L K + E E+E G W+ LD K + Q K L + A L
Sbjct: 993 PHEELL--KVISEREKEISG----LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALAST 1046
Query: 208 ------KLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLG-LAYGYNSQ 260
K+ + S E + V+AVE L +E + ++ ++ G +G+ +
Sbjct: 1047 EKMLQDKVNKTSKERQQQVEAVE-----LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKK 1101
Query: 261 YDEAVAQFSKS--IEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315
E +A S S ++V+E+++ +E + +YK + E + +L +++ +E
Sbjct: 1102 AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%)
Query: 212 VSVESENYVQAVEEFQSCLNLQEQYLEAHDRL----LAETHY---QLGLAYGYNSQYDEA 264
+ +E E Y + E + L ++ +E + + E+H Q+ ++ + Q E
Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 265 VAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSG 324
+ +K IE + L ++++AE + Y E+ ELK+LL E+++K++D+
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251
Query: 325 NVAELALKATLVESST 340
N LKA L E+ T
Sbjct: 1252 NEELNLLKAQLNETLT 1267
Score = 30.8 bits (68), Expect = 2.6
Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%)
Query: 155 PNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQL----YAAQAHL--- 207
P++ +L K + E E+E G W+ LD K + Q K L + A L
Sbjct: 993 PHEELL--KVISEREKEISG----LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALAST 1046
Query: 208 ------KLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLG-LAYGYNSQ 260
K+ + S E + V+AVE L +E + ++ ++ G +G+ +
Sbjct: 1047 EKMLQDKVNKTSKERQQQVEAVE-----LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKK 1101
Query: 261 YDEAVAQFSKS--IEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315
E +A S S ++V+E+++ +E + +YK + E + +L +++ +E
Sbjct: 1102 AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 2/65 (3%)
Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167
+A +G+ VEEEE E+ E+E VE + +E E EE++++ ++ EE + E K ++E
Sbjct: 111 SAQQGLPVEEEEVEEEEEE--VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
Query: 168 NEEEE 172
+ EE
Sbjct: 169 EKVEE 173
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 107 GNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ 166
G +E VEEEE E E+E E + DE E +E++KE D+ EE +E + ++
Sbjct: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEE--DEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
Query: 167 ENEEEEI 173
E + EI
Sbjct: 173 EEIDTEI 179
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.9 bits (102), Expect = 3e-04
Identities = 50/242 (20%), Positives = 109/242 (45%), Gaps = 16/242 (6%)
Query: 93 KSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDK-T 151
+S L+ MEN L LE + + + E+ E E N ET E+D K+ +K
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE----NKSLEQETSQLEKDKKQLEKEN 838
Query: 152 EEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFK------RQETKEAQLYAAQA 205
+ + + +++ +L+EN + IGNLE L I+K ++ KE + +A
Sbjct: 839 KRLRQQAEIKDTTLEENNVK-IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 206 HLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY---- 261
+ + + E+ V + Q N E+ +++ L + +Y
Sbjct: 898 TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE 957
Query: 262 DEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQ 321
+ + KS+E+ E ++A L +++E+ + + ++E++ +K+ ++++ ++ + Q
Sbjct: 958 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQ 1017
Query: 322 RS 323
S
Sbjct: 1018 SS 1019
Score = 38.1 bits (87), Expect = 0.016
Identities = 46/233 (19%), Positives = 94/233 (40%), Gaps = 30/233 (12%)
Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDK-----ENDKTEEMPNDSVLENKSL--QENE 169
E + ++ + E L+E N ++ + D+ E ++ S KSL + NE
Sbjct: 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNE 456
Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGE--------VSVESENYVQ 221
L+L + L K + + + T ++ A LK+ + V + VQ
Sbjct: 457 LTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ 516
Query: 222 AVEEFQSCLNLQEQYLEAH-------DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEV 274
+ Q+C NL + ++ + L + Q+ + N ++ V+ + ++
Sbjct: 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Query: 275 --------IENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319
IE +L+E +KE ++ + E ++K+ L +EK E A+E
Sbjct: 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629
Score = 37.4 bits (85), Expect = 0.028
Identities = 39/213 (18%), Positives = 96/213 (45%), Gaps = 26/213 (12%)
Query: 105 VLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKS 164
+L + LEG ++ + E E+L + + + E E D + K EE+ +++ +
Sbjct: 362 MLEDQLEGTRARSDKLHELEKENL-QLKAKLHDME--MERDMDRKKIEELMEENMTLEMA 418
Query: 165 LQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQ--AHLKLGEVSVESENYVQA 222
+++ +E +L L W++ +++ + +++ + +L ++ +E+++ +
Sbjct: 419 QKQSMDE---SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT 475
Query: 223 VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVL 282
VEE ++ ++ E A L E Q + SK +E++EN +
Sbjct: 476 VEELRTTVDSVEG--NASKILKMEKENQ----------------RLSKKVEILENEIVQE 517
Query: 283 NEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315
+ ++ + S + KE +L++ + +RE E
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Score = 36.2 bits (82), Expect = 0.062
Identities = 48/215 (22%), Positives = 93/215 (43%), Gaps = 25/215 (11%)
Query: 136 DETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDML----DLAKIIFK 191
+ T S+ N + + S LEN++ +E E +L+ +D L + +++ +
Sbjct: 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE--DLKSLYDSLIKDHEKLELLHE 1167
Query: 192 RQETKEAQLYAAQAHLKLGEVSVESEN------YVQAVEEFQSCLNLQEQYLEAHDRLLA 245
RQ ++ L + LK ++E E+ Y Q +++ +L++ +++L
Sbjct: 1168 RQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 1227
Query: 246 ET--HYQLGLAY----GYNSQYDEAVAQFSKSIEVIE----NRMAVLNEQVKEAEGSSAE 295
E H + Y G N + + +Q K EV++ N ++LN E AE
Sbjct: 1228 ENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287
Query: 296 YKKEIEELKELLPEIREKIEDAKE--SQRSGNVAE 328
+ K ++E + L K+ + E SQ GN+ E
Sbjct: 1288 FSK-LKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1321
Score = 32.0 bits (71), Expect = 1.2
Identities = 42/235 (17%), Positives = 98/235 (41%), Gaps = 22/235 (9%)
Query: 100 RMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSV 159
R E + E + ++E + + DN E E S+E +E K ++ +
Sbjct: 993 RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE-SQETTRELLKVKDRLIEVE 1051
Query: 160 LENKSLQENEEE---EIGNLELAWDMLDLAKIIFKRQ-----------ETKEAQLYAAQA 205
N +LQ ++ ++ LE + L + +RQ +T+ A+L +
Sbjct: 1052 RNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Query: 206 HLKLGEVSVESENYVQAVE------EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNS 259
L S+ ++N ++ E +S + +E +D L+ + H +L L + +
Sbjct: 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQA 1170
Query: 260 QYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKI 314
E++ +++ + V + +++ + K ++E+L+++L +EK+
Sbjct: 1171 SEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.319
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,765,780
Number of Sequences: 37866
Number of extensions: 756274
Number of successful extensions: 10118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 315
Number of HSP's successfully gapped in prelim test: 688
Number of HSP's that attempted gapping in prelim test: 5318
Number of HSP's gapped (non-prelim): 3924
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.