BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo sapiens] (449 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 867 0.0 gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 610 e-175 gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 610 e-175 gi|16262452 cingulin [Homo sapiens] 51 2e-06 gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 51 2e-06 gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 51 2e-06 gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 51 2e-06 gi|38569484 kinesin family member 21A [Homo sapiens] 48 2e-05 gi|4758646 kinesin family member 3B [Homo sapiens] 48 2e-05 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 47 4e-05 gi|4885583 Rho-associated, coiled-coil containing protein kinase... 46 8e-05 gi|31982906 cingulin-like 1 [Homo sapiens] 46 8e-05 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 1e-04 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 45 1e-04 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04 gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 45 1e-04 gi|28460688 taxilin [Homo sapiens] 45 1e-04 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 45 2e-04 gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 45 2e-04 gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 45 2e-04 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 45 2e-04 gi|221219020 NYD-SP11 protein [Homo sapiens] 44 2e-04 gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 44 2e-04 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 44 2e-04 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 44 2e-04 gi|71061468 centromere protein E [Homo sapiens] 44 2e-04 gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 3e-04 gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 3e-04 gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 44 3e-04 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 3e-04 >gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo sapiens] Length = 449 Score = 867 bits (2240), Expect = 0.0 Identities = 449/449 (100%), Positives = 449/449 (100%) Query: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP Sbjct: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60 Query: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG Sbjct: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120 Query: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW 180 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW Sbjct: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAW 180 Query: 181 DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240 DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH Sbjct: 181 DMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAH 240 Query: 241 DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI 300 DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI Sbjct: 241 DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEI 300 Query: 301 EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP 360 EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP Sbjct: 301 EELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKP 360 Query: 361 TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM 420 TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM Sbjct: 361 TDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENM 420 Query: 421 EEEAENQAESRAAVEGTVEAGATVESTAC 449 EEEAENQAESRAAVEGTVEAGATVESTAC Sbjct: 421 EEEAENQAESRAAVEGTVEAGATVESTAC 449 >gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo sapiens] Length = 788 Score = 610 bits (1574), Expect = e-175 Identities = 341/468 (72%), Positives = 366/468 (78%), Gaps = 23/468 (4%) Query: 4 ESTATAAVAAELVSAD--KIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHL------- 54 E+ A AV +LV + E+ P +T A + +++ SE + G L Sbjct: 322 ENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVN 381 Query: 55 ---VMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALE 111 V+GD + L K G E A + +L+ E+ G+ ++ Sbjct: 382 GPSVVGD-QTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 440 Query: 112 GVHVEEEEGEKTEDESLVENNDNI----------DETEGSEEDDKENDKTEEMPNDSVLE 161 + + ED+ + N+ +ETEGSEEDDKENDKTEEMPNDSVLE Sbjct: 441 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 500 Query: 162 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ Sbjct: 501 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 560 Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV Sbjct: 561 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 620 Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 341 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS Sbjct: 621 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 680 Query: 342 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 401 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE Sbjct: 681 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 740 Query: 402 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 449 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC Sbjct: 741 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 788 Score = 280 bits (717), Expect = 1e-75 Identities = 208/493 (42%), Positives = 273/493 (55%), Gaps = 49/493 (9%) Query: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP Sbjct: 1 MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP 60 Query: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG Sbjct: 61 AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG 120 Query: 121 EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLEL-- 178 EKTEDESLVENNDNIDE E ++ D E E+KSL + E ++ + E+ Sbjct: 121 EKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEK 180 Query: 179 -AWDMLDLAKIIFKRQE------------TKEAQLYAAQAHLKLGEV-SVESENYVQAVE 224 + +D++K + QE ++EA+ AA EV S + E V E Sbjct: 181 GGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAE 240 Query: 225 EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQ---YDEAVAQFSKSIEVIENRMAV 281 E +S Q E ++ E ++ ++ + ++ V K +E Sbjct: 241 EEKSVSGTDVQE-ECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAES 299 Query: 282 LNEQVKEAE-GSSAEYKKEIEELKELLPEIREKI--EDAKESQRSGNVAELALKATLVES 338 L+ VK + G +K + E + E++ ++ ++ S V A +A+ VE+ Sbjct: 300 LDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEA 359 Query: 339 -STSGFTPG---------GGGSSVSMIASRKPTDGASSSNCVTD------ISHLVRKKRK 382 S PG G + S++ + P + +S +T+ + VR K Sbjct: 360 GSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLV 419 Query: 383 PEEE----SPRKDDAKKAKQEPEVNGGSGDAVP------SGNEVSENMEEEAENQAESRA 432 P +E S + +A + +V G+ + P + NE ++ EE+ + E+ Sbjct: 420 PSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEG 479 Query: 433 AVEGTVEAGATVE 445 + E E T E Sbjct: 480 SEEDDKENDKTEE 492 >gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo sapiens] Length = 790 Score = 610 bits (1574), Expect = e-175 Identities = 341/468 (72%), Positives = 366/468 (78%), Gaps = 23/468 (4%) Query: 4 ESTATAAVAAELVSAD--KIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHL------- 54 E+ A AV +LV + E+ P +T A + +++ SE + G L Sbjct: 324 ENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVN 383 Query: 55 ---VMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALE 111 V+GD + L K G E A + +L+ E+ G+ ++ Sbjct: 384 GPSVVGD-QTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 442 Query: 112 GVHVEEEEGEKTEDESLVENNDNI----------DETEGSEEDDKENDKTEEMPNDSVLE 161 + + ED+ + N+ +ETEGSEEDDKENDKTEEMPNDSVLE Sbjct: 443 TKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLE 502 Query: 162 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ Sbjct: 503 NKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 562 Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV Sbjct: 563 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 622 Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 341 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS Sbjct: 623 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTS 682 Query: 342 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 401 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE Sbjct: 683 GFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPE 742 Query: 402 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 449 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC Sbjct: 743 VNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC 790 Score = 217 bits (552), Expect = 2e-56 Identities = 172/462 (37%), Positives = 240/462 (51%), Gaps = 49/462 (10%) Query: 32 DKVESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY 91 +++ LDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY Sbjct: 34 NRIIHLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFY 93 Query: 92 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKT 151 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDE E ++ D Sbjct: 94 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAM 153 Query: 152 EEMPNDSVLENKSLQENEEEEIGNLEL---AWDMLDLAKIIFKRQE------------TK 196 E E+KSL + E ++ + E+ + +D++K + QE ++ Sbjct: 154 GEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSE 213 Query: 197 EAQLYAAQAHLKLGEV-SVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAY 255 EA+ AA EV S + E V EE +S Q E ++ E ++ ++ Sbjct: 214 EAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQE-ECREKGGQEKQGEVIVSI 272 Query: 256 GYNSQ---YDEAVAQFSKSIEVIENRMAVLNEQVKEAE-GSSAEYKKEIEELKELLPEIR 311 + ++ V K +E L+ VK + G +K + E + Sbjct: 273 EEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVL 332 Query: 312 EKI--EDAKESQRSGNVAELALKATLVES-STSGFTPG---------GGGSSVSMIASRK 359 E++ ++ ++ S V A +A+ VE+ S PG G + S++ + Sbjct: 333 EQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQT 392 Query: 360 PTDGASSSNCVTD------ISHLVRKKRKPEEE----SPRKDDAKKAKQEPEVNGGSGDA 409 P + +S +T+ + VR K P +E S + +A + +V G+ + Sbjct: 393 PIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEK 452 Query: 410 VP------SGNEVSENMEEEAENQAESRAAVEGTVEAGATVE 445 P + NE ++ EE+ + E+ + E E T E Sbjct: 453 SPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 494 >gi|16262452 cingulin [Homo sapiens] Length = 1203 Score = 51.2 bits (121), Expect = 2e-06 Identities = 49/241 (20%), Positives = 112/241 (46%), Gaps = 5/241 (2%) Query: 97 ELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPN 156 + AR++ +L L+G+ E E ++++D+ + ++ E + E T E+ Sbjct: 930 DTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLT 989 Query: 157 DSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQ-ETKEAQLYAAQAHLKLGEVSVE 215 D V + + E+ A L+ KI +RQ + + +L +++ K + Sbjct: 990 DRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQ 1049 Query: 216 SENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY-DEAVAQFSKSIEV 274 E+ Q ++E ++ L++ +R L +L + Q+ ++ Q S ++ Sbjct: 1050 LESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKA 1109 Query: 275 IENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED-AKESQR--SGNVAELAL 331 ++ ++ E+++ +G + ++E+EE E+ +++ +I+ K+S R S + AE AL Sbjct: 1110 LKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAESAL 1169 Query: 332 K 332 K Sbjct: 1170 K 1170 Score = 37.4 bits (85), Expect = 0.028 Identities = 58/270 (21%), Positives = 109/270 (40%), Gaps = 25/270 (9%) Query: 73 LGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTE--DESLVE 130 L ++ ET+ E G + K+ +L + +L +E +EEE GEK E L + Sbjct: 557 LQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQ 616 Query: 131 NNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ-ENEEEEIGNLELAWDM-LDLAKI 188 + +T E KE +T+E E K LQ E + +E+ ++ LA + Sbjct: 617 ARASAGDTRQVEVLKKELLRTQE-------ELKELQAERQSQEVAGRHRDRELEKQLAVL 669 Query: 189 IFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETH 248 + +E + Q L ++ + E +A ++ + Q A + L ET Sbjct: 670 RVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRET- 728 Query: 249 YQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP 308 E +F + I +E ++ V E A + +++ L+ Sbjct: 729 -------------QEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQ 775 Query: 309 EIREKIEDAKESQRSGNVAELALKATLVES 338 ++ E + ++E + S A+ AL+A L E+ Sbjct: 776 QLEEALNASQEEEGSLAAAKRALEARLEEA 805 Score = 34.3 bits (77), Expect = 0.24 Identities = 61/235 (25%), Positives = 100/235 (42%), Gaps = 30/235 (12%) Query: 106 LGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDK-----ENDKTEEMPNDSVL 160 L L + VE + G + E+++L + EE K E + T + + Sbjct: 662 LEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAV 721 Query: 161 ENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY-----AAQAHLKLGEVSVE 215 E +L+E +EE N E +L L Q+ KE + A +A L+ +E Sbjct: 722 ET-TLRETQEE---NDEFRRRILGL------EQQLKETRGLVDGGEAVEARLRDKLQRLE 771 Query: 216 SENYVQAVEEFQSCLNLQEQYLEAHDRLLAET--HYQLGLA-YGYNSQ-YDEAVAQFSKS 271 +E Q +EE + +E L A R L Q GLA G Q + A+ + K Sbjct: 772 AEK--QQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQ 829 Query: 272 IEVIENRMAVLNEQVKEAEGSSAEYKKEIEEL----KELLPEIREKIEDAKESQR 322 EV+ A L EQ + + + KE+E++ K+ L +++ ++ED KE R Sbjct: 830 REVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKAR 884 >gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain 1 [Homo sapiens] Length = 1412 Score = 50.8 bits (120), Expect = 2e-06 Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 17/201 (8%) Query: 115 VEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ-ENEEEEI 173 V++ E T+ + + E+N ++ + E +KE K +++ N + + L+ + ++E++ Sbjct: 784 VQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDV 843 Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQ-LYAAQAHLKLGEVSVESENYVQAVEEFQSCLNL 232 N +L+ D ++ + Q+TK + L A LKL E E E + + L L Sbjct: 844 LNNKLS----DALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLIL 899 Query: 233 QEQYLEA-HDRLLAETHYQLGLAYGYNS---QYDEAVAQFSKSIEVIENRMAVLNEQVKE 288 Q++ ++A D ++ H G+ +Y E + Q +++I +E ++ + + K+ Sbjct: 900 QQKMVKALQDEQESQRH-------GFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKK 952 Query: 289 AEGSSAEYKKEIEELKELLPE 309 EG A K KE P+ Sbjct: 953 IEGEIATLKDNDPAPKEERPQ 973 Score = 32.0 bits (71), Expect = 1.2 Identities = 71/319 (22%), Positives = 121/319 (37%), Gaps = 33/319 (10%) Query: 39 VDSEAKKLLGLG-----QKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGK 93 ++SE +K+ L QK + +I +EA KK + N + K Sbjct: 777 LESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQ-----K 831 Query: 94 SLLELARMENGVLGNALEGVHVEEEEGEKTE-DESLVENNDNIDETEGSEEDDKENDKTE 152 LEL + VL N L EE +KT+ ESL + + E E + K Sbjct: 832 EELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMI 891 Query: 153 EMPNDSVLEN---KSLQENEEEEIGNLELAWDMLDLAKIIFKRQET----KEAQLYAAQA 205 + +L+ K+LQ+ +E + E ++++ + I + +T +E Q Sbjct: 892 MVEERLILQQKMVKALQDEQESQRHGFE--EEIMEYKEQIKQHAQTIVSLEEKLQKVTQH 949 Query: 206 HLKL-GEVSVESENYVQAVEEF-QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDE 263 H K+ GE++ +N EE Q L A D L A E Sbjct: 950 HKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQKEILSQQE 1009 Query: 264 AVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE--------YKKEIEELKELLPEIREKIE 315 + + K + +RM+ L ++ E + E KE+ LKE + ++ +E Sbjct: 1010 VIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVE 1069 Query: 316 DAKESQRSGNVAELALKAT 334 + R E AL+A+ Sbjct: 1070 ---KKDRELKALEEALRAS 1085 >gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 50.8 bits (120), Expect = 2e-06 Identities = 63/260 (24%), Positives = 107/260 (41%), Gaps = 17/260 (6%) Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169 LE V V E+ T +E D+ E EE K+ + N++ N +L++ + Sbjct: 395 LEDVQVREKLKHATSKAKKLEKQLQKDK-EKVEEFKSIPAKSNNIINETTTRNNALEKEK 453 Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229 E+E L+ D L +QET+ Q +L S ++ QS Sbjct: 454 EKEEKKLKEVMDSL--------KQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSE 505 Query: 230 LNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEA 289 L++ YL H+ ++ QL A E + + +I IE ++ +++KE Sbjct: 506 LDI---YLSRHNTAVS----QLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK 558 Query: 290 EGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG 349 E + +E K L+ ++ +K+E+AK S L A +++ SG PG G Sbjct: 559 EKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-IIQEKKSGRIPGIYG 617 Query: 350 SSVSMIASRKPTDGASSSNC 369 + A + D A SS C Sbjct: 618 RLGDLGAIDEKYDVAISSCC 637 Score = 32.0 bits (71), Expect = 1.2 Identities = 51/220 (23%), Positives = 97/220 (44%), Gaps = 45/220 (20%) Query: 122 KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWD 181 KT D +L + D++ TE KE TE+ +D E KSL++ E + N A + Sbjct: 928 KTADRNLQKAQDSVLRTE------KEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEE 981 Query: 182 MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHD 241 L ++ +L L E+ V EN A+++ + L+ + ++ H Sbjct: 982 SL--------------PEIQKEHRNL-LQELKVIQEN-EHALQKDALSIKLKLEQIDGH- 1024 Query: 242 RLLAETHYQLGLAYGYNSQY------DEAVAQFS----KSIEVIENRMAVLNE------- 284 +AE + ++ + S+ D + + S + +E I+N ++ N+ Sbjct: 1025 --IAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEAR 1082 Query: 285 --QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322 ++K G+ AEYKK+ E + + E+ +KI ++S R Sbjct: 1083 CHEMKPNLGAIAEYKKKEELYLQRVAEL-DKITYERDSFR 1121 Score = 30.0 bits (66), Expect = 4.4 Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 14/115 (12%) Query: 210 GEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFS 269 GE ++ E E F+ ++ + Y+ + +AE Q + E + + Sbjct: 300 GEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQ-------KEKIHEDTKEIN 352 Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP-------EIREKIEDA 317 + ++ N M N+ VK+ E + K IEE KE ++REK++ A Sbjct: 353 EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHA 407 >gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 50.8 bits (120), Expect = 2e-06 Identities = 63/260 (24%), Positives = 107/260 (41%), Gaps = 17/260 (6%) Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169 LE V V E+ T +E D+ E EE K+ + N++ N +L++ + Sbjct: 395 LEDVQVREKLKHATSKAKKLEKQLQKDK-EKVEEFKSIPAKSNNIINETTTRNNALEKEK 453 Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229 E+E L+ D L +QET+ Q +L S ++ QS Sbjct: 454 EKEEKKLKEVMDSL--------KQETQGLQKEKESREKELMGFSKSVNEARSKMDVAQSE 505 Query: 230 LNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEA 289 L++ YL H+ ++ QL A E + + +I IE ++ +++KE Sbjct: 506 LDI---YLSRHNTAVS----QLTKAKEALIAASETLKERKAAIRDIEGKLPQTEQELKEK 558 Query: 290 EGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGG 349 E + +E K L+ ++ +K+E+AK S L A +++ SG PG G Sbjct: 559 EKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDA-IIQEKKSGRIPGIYG 617 Query: 350 SSVSMIASRKPTDGASSSNC 369 + A + D A SS C Sbjct: 618 RLGDLGAIDEKYDVAISSCC 637 Score = 32.0 bits (71), Expect = 1.2 Identities = 51/220 (23%), Positives = 97/220 (44%), Gaps = 45/220 (20%) Query: 122 KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWD 181 KT D +L + D++ TE KE TE+ +D E KSL++ E + N A + Sbjct: 928 KTADRNLQKAQDSVLRTE------KEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEE 981 Query: 182 MLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHD 241 L ++ +L L E+ V EN A+++ + L+ + ++ H Sbjct: 982 SL--------------PEIQKEHRNL-LQELKVIQEN-EHALQKDALSIKLKLEQIDGH- 1024 Query: 242 RLLAETHYQLGLAYGYNSQY------DEAVAQFS----KSIEVIENRMAVLNE------- 284 +AE + ++ + S+ D + + S + +E I+N ++ N+ Sbjct: 1025 --IAEHNSKIKYWHKEISKISLHPIEDNPIEEISVLSPEDLEAIKNPDSITNQIALLEAR 1082 Query: 285 --QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322 ++K G+ AEYKK+ E + + E+ +KI ++S R Sbjct: 1083 CHEMKPNLGAIAEYKKKEELYLQRVAEL-DKITYERDSFR 1121 Score = 30.0 bits (66), Expect = 4.4 Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 14/115 (12%) Query: 210 GEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFS 269 GE ++ E E F+ ++ + Y+ + +AE Q + E + + Sbjct: 300 GEKNIAIEFLTLENEIFRKKNHVCQYYIYELQKRIAEMETQ-------KEKIHEDTKEIN 352 Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLP-------EIREKIEDA 317 + ++ N M N+ VK+ E + K IEE KE ++REK++ A Sbjct: 353 EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQVREKLKHA 407 >gi|38569484 kinesin family member 21A [Homo sapiens] Length = 1661 Score = 48.1 bits (113), Expect = 2e-05 Identities = 52/219 (23%), Positives = 94/219 (42%), Gaps = 36/219 (16%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPND-------SVL 160 N LE +E + E+E E D+ID E S+E D E+D+ D + Sbjct: 584 NELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAI 643 Query: 161 ENKSLQ--ENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESEN 218 + K + EN ++ + L+ ++ K++ + + ++ QL Q LG V SE Sbjct: 644 KQKLIDELENSQKRLQTLKKQYE----EKLMMLQHKIRDTQLERDQVLQNLGSVESYSEE 699 Query: 219 YVQAV----EEFQSCLNLQEQYLEA----HDRLLAETHYQLGLAYGYNSQYDEAVAQFSK 270 + V E+ +N + Q L+A H RLL SQY++ + + + Sbjct: 700 KAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKN-----------QSQYEKQLKKLQQ 748 Query: 271 SIEVIENRMAVLNEQVKE----AEGSSAEYKKEIEELKE 305 + ++ L +Q+KE A + + +EI +LK+ Sbjct: 749 DVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKK 787 Score = 40.0 bits (92), Expect = 0.004 Identities = 51/241 (21%), Positives = 114/241 (47%), Gaps = 39/241 (16%) Query: 121 EKTEDESLVENNDNIDETEGSEED----DKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176 EK + +S+ DN D + +E+ ++EN++ E + V +++ +E EEEE ++ Sbjct: 552 EKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDI 611 Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCL-NLQEQ 235 + + D + E+ E Y A E++++ + + +E Q L L++Q Sbjct: 612 D-GGESSDESD-----SESDEKANYQADLANITCEIAIK-QKLIDELENSQKRLQTLKKQ 664 Query: 236 YLEAHDRL---LAETHYQ-------LGLAYGYNSQYDEAV-AQFSKSIEVIENRMAVLNE 284 Y E L + +T + LG Y+ + + V +++ K ++ + + L Sbjct: 665 YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQA 724 Query: 285 QVKEAE---GSSAEYKKEIEELKE-----------LLPEIREKIEDAK--ESQRSGNVAE 328 KE + ++Y+K++++L++ L+ +++E+ E A+ ES+R+ +A+ Sbjct: 725 AQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ 784 Query: 329 L 329 L Sbjct: 785 L 785 Score = 33.1 bits (74), Expect = 0.53 Identities = 34/193 (17%), Positives = 79/193 (40%), Gaps = 7/193 (3%) Query: 258 NSQYDEAVAQFSKSIEVIENRMAVL-NEQVKEAEGSSAEYKKEIEELKELLPEIREKIED 316 N+ + ++++ + +R+ L ++Q + E EE+ ++ ++IED Sbjct: 432 NNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGN---EEISNMIHSYIKEIED 488 Query: 317 AKESQRSGNVAELALKATLVESSTSG-FTPGGGGSSVSMIASRKPTDGASSSNCVTDISH 375 + L+ L ++ + G S ++++S K T D+ Sbjct: 489 LRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDL-AKKDLEK 547 Query: 376 LVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENME-EEAENQAESRAAV 434 L RK+++ ++ K+D QE + G + + EV E+ E + E++ E Sbjct: 548 LKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEE 607 Query: 435 EGTVEAGATVEST 447 E ++ G + + + Sbjct: 608 EDDIDGGESSDES 620 >gi|4758646 kinesin family member 3B [Homo sapiens] Length = 747 Score = 47.8 bits (112), Expect = 2e-05 Identities = 57/243 (23%), Positives = 102/243 (41%), Gaps = 40/243 (16%) Query: 100 RMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDD--KENDKTEEMPND 157 R E G G G EEEEGE+ E+ EG ++DD +E + E+ Sbjct: 383 RREGGGSGG---GGEEEEEEGEEGEE-------------EGDDKDDYWREQQEKLEIEKR 426 Query: 158 SVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 217 +++E+ SL E+ + E M DL R+E A++ A+ ++ V + Sbjct: 427 AIVEDHSLVAEEKMRLLK-EKEKKMEDL------RREKDAAEMLGAKIKAMESKLLVGGK 479 Query: 218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN 277 N V E Q L + Q + R E Q+ DE + ++ ++ Sbjct: 480 NIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM-------ESRDEETLELKETYSSLQQ 532 Query: 278 RMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGN--VAELALKATL 335 + + +++K+ K EI +L+E E I++ +E +++ N EL LK + Sbjct: 533 EVDIKTKKLKKLFSKLQAVKAEIHDLQE------EHIKERQELEQTQNELTRELKLKHLI 586 Query: 336 VES 338 +E+ Sbjct: 587 IEN 589 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 47.0 bits (110), Expect = 4e-05 Identities = 56/228 (24%), Positives = 100/228 (43%), Gaps = 33/228 (14%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175 E E EK E + I+ETE + ++ND + N E+K +E EEE+ Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK--EDKEKEEEEEEKPKR 200 Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVE----SENYVQAVEEFQSCLN 231 + + ++ + ++T E+Q LK G++S E E Q +E Sbjct: 201 GSIGENQVE----VMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEK 256 Query: 232 LQEQYLEAHD----RLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEV--------IENRM 279 ++E+ E + RL AE ++ ++ D+ +A IE E R Sbjct: 257 MEEEDKERAEAERARLEAEERERI------KAEQDKKIADERARIEAEEKAAAQERERRE 310 Query: 280 AVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED-----AKESQR 322 A E+++E E +AE ++ I+E ++ E R++I++ A+E QR Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358 Score = 43.9 bits (102), Expect = 3e-04 Identities = 54/242 (22%), Positives = 101/242 (41%), Gaps = 16/242 (6%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 N E EEEE EK + S+ EN + E + E +E + N + + QE Sbjct: 183 NKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET-VVMSLKNGQISSEEPKQE 241 Query: 168 NEEE----EIGNLE-LAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGE--VSVESENYV 220 E E EI + E + + + A+ R E +E + A+ K+ + +E+E Sbjct: 242 EEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKA 301 Query: 221 QAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMA 280 A E + +E+ E R AE ++ + ++ A+ + I+ E R A Sbjct: 302 AAQERERREAEERERMREEEKR-AAEERQRI-------KEEEKRAAEERQRIKEEEKRAA 353 Query: 281 VLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340 +++KE E +AE ++ +E ++ E+ + + ++ + E +K VE Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKI 413 Query: 341 SG 342 G Sbjct: 414 EG 415 Score = 37.0 bits (84), Expect = 0.036 Identities = 49/228 (21%), Positives = 98/228 (42%), Gaps = 18/228 (7%) Query: 116 EEEEGEKTEDES----LVENNDNIDETE--GSEEDDKENDK--TEEMPNDSVLENKSLQE 167 EEEE K E++ L E + ET+ G + + K K E+ + L+ L++ Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435 Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227 EE+ ++ + L K FK++E K+ ++ K E E ++++ + F Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI------KKDKEPKEEVKSFMDRKKGFT 489 Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQF--SKSIEVIENRMA-VLNE 284 + +++ + T + G +++ E Q K +E + R +E Sbjct: 490 EVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESE 549 Query: 285 QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALK 332 + ++ + E E+EELK+ E R K+ + +E +R A+ L+ Sbjct: 550 EFEKLKQKQQEAALELEELKKKREE-RRKVLEEEEQRRKQEEADRKLR 596 >gi|4885583 Rho-associated, coiled-coil containing protein kinase 1 [Homo sapiens] Length = 1354 Score = 45.8 bits (107), Expect = 8e-05 Identities = 92/411 (22%), Positives = 161/411 (39%), Gaps = 38/411 (9%) Query: 50 GQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNA 109 G ++GD+ A + + QE L + E EA S E +E L Sbjct: 618 GHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID-LNYK 676 Query: 110 LEGVH--VEEEEGE-KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ 166 L+ + +E+E E K L + + +I+E + + E EE EN+ +Q Sbjct: 677 LKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQ 736 Query: 167 ENEEEEIGNLELAWDMLDLAKIIFKRQ----ETKEAQLYAAQAHLKLGEVSVESENYVQA 222 ++ + +++L L + ++ E K L Q K + +++E QA Sbjct: 737 IEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNK--RLLLQNELKTQA 794 Query: 223 VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVL 282 E + L++Q + + LL + +AQ +K E +M L Sbjct: 795 FEA-DNLKGLEKQMKQEINTLLEAKRL-----------LEFELAQLTKQYRGNEGQMREL 842 Query: 283 NEQVKEAEGSSAEYKKEIEELKELLPEIREK-IEDAKESQRSGNVAE-LALKATLVESST 340 +Q++ + S YK +++ELKE EI EK E+ K+ Q N E LA + L E+ Sbjct: 843 QDQLEAEQYFSTLYKTQVKELKE---EIEEKNRENLKKIQELQNEKETLATQLDLAETKA 899 Query: 341 SGFTPGGGGSSVSMIASRKPTDGASSSNC--VTDISHLVRKKRKPEEESPRKDDAKKAKQ 398 G + + A+S N +TD H V R E S D + ++ Sbjct: 900 ESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTV--SRLEEANSMLTKDIEILRR 957 Query: 399 EPEVNGGSGDAVPSGNEVSENMEEEAENQAES-RAAVEGTVEAGATVESTA 448 E E + + E + E E + + +AA E + T+++ A Sbjct: 958 ENE------ELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQA 1002 >gi|31982906 cingulin-like 1 [Homo sapiens] Length = 1302 Score = 45.8 bits (107), Expect = 8e-05 Identities = 66/318 (20%), Positives = 127/318 (39%), Gaps = 56/318 (17%) Query: 129 VENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKI 188 V+N NI E + E +++ N+ V EN +LQ+ EE G L + L K+ Sbjct: 634 VKNQQNIKEERERMRANLEELRSQH--NEKVEENSTLQQRLEESEGELRKNLEELFQVKM 691 Query: 189 IFKRQETK----EAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYL--EAHDR 242 ++ +T+ + QL L + S + E E Q+ +LQ+ + E + Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751 Query: 243 LLAETHYQLGLAYG---------------YNSQYD-------EAVAQFSKSIEVI----- 275 LL + +L G QYD E+V + +K++EV+ Sbjct: 752 LLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSN 811 Query: 276 ---------ENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNV 326 E R+ +L E+ ++ +G S E ++ + +L+ + +++ AKE+ + Sbjct: 812 TSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEG 871 Query: 327 AELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDG---ASSSNCVTDISHLVRKKRKP 383 L+ LV + +++R+ + A+ N + K Sbjct: 872 EIRQLEEALVHARK---------EEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKL 922 Query: 384 EEESPRKDDAKKAKQEPE 401 +EES +K+ ++ K E E Sbjct: 923 KEESEQKEQLRRLKNEME 940 Score = 41.2 bits (95), Expect = 0.002 Identities = 53/217 (24%), Positives = 93/217 (42%), Gaps = 22/217 (10%) Query: 117 EEEGEKTE----DESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEE 172 E E +TE + L E +D +D + SE+ +K E + L++ + + E+E+ Sbjct: 692 EREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751 Query: 173 IGNLELAWDMLDLAKIIFKRQ---ETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSC 229 + L L K K + +E Q +L + E + VE S Sbjct: 752 L--LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASR 809 Query: 230 LNLQEQ---YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQV 286 N EQ E +LL E + +L G + + + VAQ + IE ++ A E + Sbjct: 810 SNTSEQDQAGTEMRVKLLQEENEKL---QGRSEELERRVAQLQRQIEDLKGDEAKAKETL 866 Query: 287 KEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323 K+ EG EI +L+E L R++ ++A ++R+ Sbjct: 867 KKYEG-------EIRQLEEALVHARKEEKEAVSARRA 896 Score = 35.4 bits (80), Expect = 0.11 Identities = 44/203 (21%), Positives = 85/203 (41%), Gaps = 17/203 (8%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175 E+E+ + + L + E S D+E DK +E + E ++L+E+ EE N Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSH--DQEMDKLKEQYD---AELQALRESVEEATKN 802 Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQ 235 +E ++ R T E + +KL + E+E EE + + ++ Sbjct: 803 VE----------VLASRSNTSEQDQAGTEMRVKL--LQEENEKLQGRSEELERRVAQLQR 850 Query: 236 YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE 295 +E A+ L G Q +EA+ K + + L +++ A+G+ ++ Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910 Query: 296 YKKEIEELKELLPEIREKIEDAK 318 +E ++L E L E E+ E + Sbjct: 911 TTQEQKQLSEKLKEESEQKEQLR 933 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 45.4 bits (106), Expect = 1e-04 Identities = 40/209 (19%), Positives = 93/209 (44%), Gaps = 18/209 (8%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGS--EEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173 E+EE + ++E + E + + E E+++K + E+M + + + EEE+I Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372 Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233 E KRQE +EA+++ + ++ E + + + ++E + + Q Sbjct: 373 REQE-------------KRQE-QEAKMWRQEEKIREQEEKIREQE--EMMQEQEEKMGEQ 416 Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSS 293 E+ + + + E ++ + ++ + + + I E M E++ E EG Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476 Query: 294 AEYKKEIEELKELLPEIREKIEDAKESQR 322 E + +++E +E + EKI + ++ R Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIR 505 Score = 45.1 bits (105), Expect = 1e-04 Identities = 36/205 (17%), Positives = 91/205 (44%), Gaps = 9/205 (4%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGS-EEDDKENDKTEEMPNDSVLENKSLQENEEEEIG 174 E+EE + ++E + E + I E E E +K ++ E+ + + + ++ +E ++ Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386 Query: 175 NLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQE 234 E KI + ++ +E + + K+GE + + ++E + + QE Sbjct: 387 RQE--------EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438 Query: 235 QYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSA 294 + + ++ + E ++ + +E + + + E +M E+++ E Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498 Query: 295 EYKKEIEELKELLPEIREKIEDAKE 319 E +K+I E +E + E E +++ +E Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEE 523 Score = 36.6 bits (83), Expect = 0.048 Identities = 37/223 (16%), Positives = 94/223 (42%), Gaps = 27/223 (12%) Query: 126 ESLVENNDNIDETEGSEEDD--KENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDML 183 ++ VE N+ + +E+ ++ +K +E + + ++E EE+ E+ W+ Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKE 329 Query: 184 DLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF----------------Q 227 + + + KE ++ + + E E E Q E+ + Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389 Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287 + QE+ + + ++ E ++G + +E + + + ++ E +M E+++ Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMG-------EQEEKMWEQEEEMQEQEEKMRRQEEKIR 442 Query: 288 EAEGSSAEYKKEIEELKELLPEIREKI--EDAKESQRSGNVAE 328 E E E +++I E +E++ E EK+ ++ K ++ + E Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485 Score = 34.7 bits (78), Expect = 0.18 Identities = 34/198 (17%), Positives = 84/198 (42%), Gaps = 12/198 (6%) Query: 116 EEEEGEKTEDESLVENNDNIDETEG--SEEDDKENDKTEEM--PNDSVLENKSLQENEEE 171 E+E ++E + E + I E E E+++K ++ E+M + + E + +EE Sbjct: 380 EQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439 Query: 172 EIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLN 231 +I E KI + ++ +E + + K+GE + ++E + + Sbjct: 440 KIREQE--------KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491 Query: 232 LQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEG 291 QE+ + ++ + E ++ + +E + + + + E +M E+++ E Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551 Query: 292 SSAEYKKEIEELKELLPE 309 E + + + +E + E Sbjct: 552 KMREQEVRLRQQEEKMQE 569 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 45.4 bits (106), Expect = 1e-04 Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 2/64 (3%) Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170 EG E+E+ E E+E E +D ++ EG E+DD+ +++ EE D E++ E+EE Sbjct: 173 EGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDE--EDEDEDEDEE 230 Query: 171 EEIG 174 EE G Sbjct: 231 EEEG 234 Score = 32.0 bits (71), Expect = 1.2 Identities = 13/55 (23%), Positives = 30/55 (54%) Query: 119 EGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173 +G ED+ +++ +D + EED++ D+ +E D E +++E+E++ Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDV 200 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 45.1 bits (105), Expect = 1e-04 Identities = 45/239 (18%), Positives = 98/239 (41%), Gaps = 17/239 (7%) Query: 100 RMENGVLGNALEGVHVEEEE--GEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPND 157 R + G +G EG E+EE GE+ E E E + +++++ ++ E++ Sbjct: 188 REQEGQMGEQ-EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246 Query: 158 SVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESE 217 K ++ ++E E M + + + K++E E + + ++ E + Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306 Query: 218 NYVQAVEEFQSCLNLQEQYLEAHDRLLAE--------------THYQLGLAYGYNSQYDE 263 + + E + + QE+ + + + E Q+G + +E Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366 Query: 264 AVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQR 322 V + + + E +M EQ+++ E E K+++ E KE + E E++ + KE R Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMR 425 Score = 41.2 bits (95), Expect = 0.002 Identities = 37/209 (17%), Positives = 87/209 (41%), Gaps = 12/209 (5%) Query: 115 VEEEEGEKTEDESLV-ENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEI 173 V E+EG+ E E V E + E EG + + + +E V E + +E ++ Sbjct: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---GQVREQEGQVREQEGQV 124 Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233 E ++ + + +E + + ++ E + V E + + Q Sbjct: 125 REQE--------GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 176 Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSS 293 E + + + E Q+G G + +E + + + ++ E +M EQ+++ E Sbjct: 177 EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQM 236 Query: 294 AEYKKEIEELKELLPEIREKIEDAKESQR 322 E ++++++ +E + + E++ +E R Sbjct: 237 GEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265 Score = 28.9 bits (63), Expect = 9.9 Identities = 54/278 (19%), Positives = 103/278 (37%), Gaps = 25/278 (8%) Query: 160 LENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENY 219 L+ K+ + EE ++ E + L + ++ K + K Q + G+V E E Sbjct: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR-EQEGQ 67 Query: 220 VQA----VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVI 275 V+ V E + + QE + + + E Q+ G + + V + + Sbjct: 68 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 127 Query: 276 ENRMAVLNEQVKEAEGSSAEYKKEIEE----LKELLPEIREKIEDAKESQRSGNVAELAL 331 E ++ QV+E EG E + ++ E ++E ++RE+ +E + G V E Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQVREQEG 185 Query: 332 KATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKD 391 + E G G + ++ G ++ +EE RK Sbjct: 186 QVREQE--------GQMGEQEGQMGEQEEQMGEQEEQMQKQ-----EEQMGEQEEQMRKQ 232 Query: 392 DAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAE 429 + + +QE +V + V E EE+ Q E Sbjct: 233 EEQMGEQEEQVQ-KQEEQVQKQEEQMRKQEEQMREQEE 269 >gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] Length = 284 Score = 45.1 bits (105), Expect = 1e-04 Identities = 52/235 (22%), Positives = 98/235 (41%), Gaps = 32/235 (13%) Query: 95 LLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDETEGS-----EEDDKEN 148 L EL + E+ +L E + LVE D E + EE +K Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120 Query: 149 DKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLK 208 D++E V+E+++ ++ E+ EI ++L KEA+ A A K Sbjct: 121 DESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHIAEDADRK 161 Query: 209 LGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQF 268 EV+ + + +S L E+ E + AE +L + ++ Sbjct: 162 YEEVA-------RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKY 214 Query: 269 SKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323 S+ + E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE S Sbjct: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269 >gi|28460688 taxilin [Homo sapiens] Length = 546 Score = 45.1 bits (105), Expect = 1e-04 Identities = 71/308 (23%), Positives = 131/308 (42%), Gaps = 55/308 (17%) Query: 42 EAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARM 101 E KK GLG++ ++ ++ +E + L KKY E E + + ++L + Sbjct: 161 EKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNS-----QKQMKLLQK 215 Query: 102 ENGVLGNALEGVHVEEEEG--EKTEDESL---VENNDNIDETEGSEEDDKENDKTEEMP- 155 + L + + E + +++ ESL ++ ++ + EG + +E +K +E+ Sbjct: 216 KQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTS 275 Query: 156 ------NDSVL--------------ENKSLQENEEEEIGNLELAWDMLDLAKIIFK---- 191 ND L EN L E ++ I EL + +D +FK Sbjct: 276 HFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDK---VFKHKDL 332 Query: 192 RQETKEAQLYAAQAHLKLGEVSVESEN---YVQAVEEFQSCLNLQEQYLEAHDRLLAETH 248 +Q+ +A+L AQ LK E + E +AVE + C +++Q ETH Sbjct: 333 QQQLVDAKLQQAQEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQ----------ETH 382 Query: 249 YQLGLAYGYNSQYDEAVAQFSKSIEV---IENRMAVLNEQVKEAEGSSAEYKKEIEELKE 305 + LA Y +++E SKS EV + M + +++K+ E + Y+ E + Sbjct: 383 LKQQLAL-YTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNK 441 Query: 306 LLPEIREK 313 L E+ E+ Sbjct: 442 ALLEMAEE 449 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 44.7 bits (104), Expect = 2e-04 Identities = 55/229 (24%), Positives = 103/229 (44%), Gaps = 30/229 (13%) Query: 118 EEGEKTEDESLVENNDNIDETEGSEEDDKEND--KTEEMPNDSVL---------ENKSLQ 166 +E E+ + +++ E + I +TE + K+ D EE+ D ++ E K LQ Sbjct: 626 QEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ 685 Query: 167 E---NEEEEIGNLELA--WDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQ 221 E N+E++I E A + + L K ++ Q K+ L+ Q ++ + +E E + Sbjct: 686 ERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE---K 742 Query: 222 AVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSI-EVIENRMA 280 A+E N + LE D + + L S Y+E + QF + + E NR+ Sbjct: 743 ALEH----KNRMSRMLEDRDLFV------MRLKAARQSVYEEKLKQFEERLAEERHNRLE 792 Query: 281 VLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAEL 329 Q KE + +KE EE + ++ ++ E+ + ++R+ EL Sbjct: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEEL 841 >gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] Length = 284 Score = 44.7 bits (104), Expect = 2e-04 Identities = 57/238 (23%), Positives = 101/238 (42%), Gaps = 38/238 (15%) Query: 95 LLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDETEGS-----EEDDKEN 148 L EL + E+ +L E + LVE D E + EE +K Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120 Query: 149 DKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLK 208 D++E V+E+++ ++ E+ EI ++L KEA+ A A K Sbjct: 121 DESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHIAEDADRK 161 Query: 209 LGEVS---VESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAV 265 EV+ V E+ ++ EE Q + LE R++ +T L A SQ ++ Sbjct: 162 YEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY 221 Query: 266 AQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRS 323 E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE S Sbjct: 222 ----------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLS 269 >gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] Length = 284 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/182 (22%), Positives = 82/182 (45%), Gaps = 26/182 (14%) Query: 142 EEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY 201 EE +K D++E V+E+++ ++ E+ EI ++L KEA+ Sbjct: 114 EEAEKAADESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHI 154 Query: 202 AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY 261 A A K EV+ + + +S L E+ E + AE +L Sbjct: 155 AEDADRKYEEVA-------RKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSL 207 Query: 262 DEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQ 321 + ++S+ + E + VL++++KEAE + ++ + +L++ + ++ EK+ AKE Sbjct: 208 EAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEEN 267 Query: 322 RS 323 S Sbjct: 268 LS 269 Score = 41.2 bits (95), Expect = 0.002 Identities = 40/213 (18%), Positives = 90/213 (42%), Gaps = 15/213 (7%) Query: 129 VENNDNIDETEGSEEDDKE-NDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAK 187 ++ + +D E +E D K D+++++ ++ V K L+ E+E E D + + Sbjct: 13 LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE 72 Query: 188 IIFKRQETKEAQLYAAQAHLKLGEVSVES------------ENYVQAVEEFQSCLNLQEQ 235 + K+ EA + + ++L E ++ E +A +E + + + E Sbjct: 73 LAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIES 132 Query: 236 YLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAE 295 + + + QL A D + ++ + +IE+ + E+ + +EG AE Sbjct: 133 RAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAE 192 Query: 296 YKKEIEELKELLPEIREKIEDAKESQRSGNVAE 328 ++E++ + L + + E K SQ+ E Sbjct: 193 LEEELKTVTNNLKSLEAQAE--KYSQKEDRYEE 223 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 44.7 bits (104), Expect = 2e-04 Identities = 77/354 (21%), Positives = 136/354 (38%), Gaps = 27/354 (7%) Query: 111 EGVHVEEEEGE---KTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 EG+ E EGE ++E E + E EG + + E+ + E ++ + Sbjct: 1833 EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA--------Q 1884 Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQ--LYAAQAHLKLGEVSVESE-----NYV 220 E E++ E W++ ++ + KEAQ + +A GE ESE Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944 Query: 221 QAVEEFQSCLNLQEQYL---EAHDRLLAETHYQLGLAYGYNSQYDEAVAQ-FSKSIEV-- 274 +A +E + + + + EA + E+ L +Q E AQ S+ +E Sbjct: 1945 EAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPE 2004 Query: 275 IENRMAVLNEQVK-EAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333 E M E+ + E++G A+ K E EE +E+ E ++ DA+ E +A Sbjct: 2005 AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064 Query: 334 TLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKD-D 392 E S + A + S V ++ E+P + + Sbjct: 2065 QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124 Query: 393 AKKAKQEPEVNGGSGDAVPSGNEV-SENMEEEAENQAESRAAVEGTVEAGATVE 445 A+ + E G+A P V +++ E EA+ ++E A E EA +E Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELE 2178 Score = 31.6 bits (70), Expect = 1.5 Identities = 72/340 (21%), Positives = 120/340 (35%), Gaps = 55/340 (16%) Query: 110 LEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENE 169 +E EEE ++ED +E E EG + + E+ + E E + +E Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEG----EMQEAEEEA 2016 Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENY--VQAVEEFQ 227 + E +E + E +EAQ + G+ ES+ +A EE Q Sbjct: 2017 QPESDGVEAQ-----------PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ 2065 Query: 228 SCL-NLQEQYLEAH------DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMA 280 +QE EAH D AE Q + G + E AQ ++ IE E Sbjct: 2066 EAEGEVQEAEGEAHPESEDVDAQEAEGEAQ-PESEGVEAPEAEGEAQKAEGIEAPETEGE 2124 Query: 281 VLNE----QVKEAEGSSAEYKKEIE---------------ELKELLPEIREKIE--DAKE 319 E + EAEG + + +E E +E E + ++E +A E Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184 Query: 320 SQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRK 379 ++ ++A E G A +P +G + Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEP-EGVETPE--------AEG 2235 Query: 380 KRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSEN 419 + +PE E + + K + Q +G S +A S + V E+ Sbjct: 2236 EAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED 2275 Score = 30.0 bits (66), Expect = 4.4 Identities = 26/100 (26%), Positives = 42/100 (42%), Gaps = 18/100 (18%) Query: 134 NIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE--------EEIGNLELAWDMLDL 185 N DE E E+ + + E++ ++V E L+E +E EE LE L Sbjct: 1272 NEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGL 1331 Query: 186 AKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE 225 + + +ETKE + GE E E ++ +EE Sbjct: 1332 QEEGVQLEETKETE----------GEGQQEEEAQLEEIEE 1361 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 44.3 bits (103), Expect = 2e-04 Identities = 47/239 (19%), Positives = 101/239 (42%), Gaps = 32/239 (13%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 N EG VEE++ E+E+L + + E E ++E E+ + + ++K Sbjct: 1736 NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK---EKLAQHKEKMP 1792 Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF- 226 EEE +G KR++ E ++ AQ + E ++ ++EE Sbjct: 1793 EEEERLGR---------------KREQLIEKKMKLAQ----------KRERWINSMEELT 1827 Query: 227 -QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQ 285 + Q++ L + LA+ +L E + K + ++N++ + N+ Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKI 1887 Query: 286 VKEAEGSSAEYKKEIEELKELLPEIREKIEDAKES--QRSGNVAELALKATLVESSTSG 342 + + E + K+ + + KE L E +K+ ++S ++ +A+ +K L ++ G Sbjct: 1888 LAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946 Score = 38.9 bits (89), Expect = 0.010 Identities = 50/208 (24%), Positives = 92/208 (44%), Gaps = 12/208 (5%) Query: 115 VEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEE-EI 173 VE EE E ESL++ + + EE+++E + EE + V E + ++ EEE E Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEE--EEREEEEVREEEEERKEEEEGEE 2277 Query: 174 GNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQ 233 +E + K K++E +E + + + E E+E+ EE +SC +L+ Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE--EETESLSDEEEEEESC-SLE 2334 Query: 234 EQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIEN---RMAVLNEQVKEAE 290 E+ + L E ++L + + E V + + + R+ VL +K+ Sbjct: 2335 EEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLM 2394 Query: 291 GSSAEYKKEIEELKELLPEIREKIEDAK 318 ++ E K E+ +PE + ED K Sbjct: 2395 STALEMK---EKTPVPVPEKQISWEDKK 2419 Score = 34.7 bits (78), Expect = 0.18 Identities = 51/238 (21%), Positives = 99/238 (41%), Gaps = 55/238 (23%) Query: 117 EEEGEKT---EDESLVENNDNIDETEGSEEDDKENDKTEEMPN--DSVLENKSLQENEEE 171 +EE EK E+E L + + + E ++DK+ K EE +++L +KS ++ ++ Sbjct: 1482 KEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKL-KWEEWKQVWENMLSSKSKEQQYKD 1540 Query: 172 EIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHL----KLGEVSVESENYVQAVEEFQ 227 E + + L + + + E KE Q+ Q H+ K + + + + + Sbjct: 1541 E--------EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592 Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287 L +E+ L +R LA+ +L AY +Q D +AQ Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQ-------------------- 1632 Query: 288 EAEGSSAEYKKEIEELKELLPEIREKI----------------EDAKESQRSGNVAEL 329 AEG A+ ++ + + E L + EK+ E+ K +++ G +AE+ Sbjct: 1633 -AEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEV 1689 Score = 33.1 bits (74), Expect = 0.53 Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 26/203 (12%) Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176 E+ E T+DE + + +KE TEE + ++ + ++EEE G + Sbjct: 2127 EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEE--GGI 2184 Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQY 236 E + L + KR+E K E + V+E +S +E + Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDK--------------PKEKFSSQVDEVES----EEHF 2226 Query: 237 LEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEY 296 E + LL E Q L+ + +E + + + E E+ +E EG + Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEE------ERKEEEEGEEKQV 2280 Query: 297 KKEIEELKELLPEIREKIEDAKE 319 +KE EE K+ E +++ KE Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKE 2303 Score = 32.3 bits (72), Expect = 0.90 Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 15/100 (15%) Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKS------ 164 E V EEE E+ E+E E +E E ++ KE K E + V E K Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEE-KKKKKKEKKKEEVQEKEEVFEEKEEIMSEE 2316 Query: 165 -----LQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQ 199 E EEEE +LE + +D K I K+++ + Q Sbjct: 2317 ETESLSDEEEEEESCSLE---EEVDREKEILKKEKQFKLQ 2353 Score = 32.0 bits (71), Expect = 1.2 Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 24/227 (10%) Query: 111 EGVHVEEE---EGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 E V +EEE EGE+ E + + E +I E ++ + E+ E K QE Sbjct: 1542 EEVTLEEEVSREGEEKEQQ-VTEEQRHIQEEHKWARIHRKRARAEKKRAQE--ERKLAQE 1598 Query: 168 NEEEEIGNLELAWDMLDLA----KIIFKRQETKEAQLYAAQAHLKLGE----VSVESENY 219 E+ +LA + LA KI +E +A+ AQ L + +S E+E Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658 Query: 220 VQA----VEEFQSCLNLQEQYLEAHDRL------LAETHYQLGLAYGYNSQYDEAVAQFS 269 Q ++++ +E+ + +L LA+ +L ++ +AQ Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718 Query: 270 KSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIED 316 + +E ++ E++ + EG E KK++ E +E L REK+ + Sbjct: 1719 EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765 >gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] Length = 284 Score = 44.3 bits (103), Expect = 2e-04 Identities = 46/185 (24%), Positives = 85/185 (45%), Gaps = 32/185 (17%) Query: 142 EEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY 201 EE +K D++E V+E+++ ++ E+ EI ++L KEA+ Sbjct: 114 EEAEKAADESER--GMKVIESRAQKDEEKMEIQEIQL-----------------KEAKHI 154 Query: 202 AAQAHLKLGEVS---VESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYN 258 A A K EV+ V E+ ++ EE Q + LE R++ +T L A Sbjct: 155 AEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKY 214 Query: 259 SQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAK 318 SQ ++ E + VL++++KEAE + ++ + +L++ + ++ EK+ AK Sbjct: 215 SQKEDRY----------EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAK 264 Query: 319 ESQRS 323 E S Sbjct: 265 EENLS 269 Score = 35.0 bits (79), Expect = 0.14 Identities = 40/214 (18%), Positives = 89/214 (41%), Gaps = 26/214 (12%) Query: 129 VENNDNIDETEGSEEDDKE-NDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAK 187 ++ + +D E +E D K D+++++ ++ V K L+ E+E E D + + Sbjct: 13 LDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLE 72 Query: 188 IIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAET 247 + K+ EA + + ++L E ++ +A E + L E+ +A D Sbjct: 73 LAEKKATDAEADVASLNRRIQLVEEELD-----RAQERLATALQKLEEAEKAAD------ 121 Query: 248 HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELL 307 + + + + E +M + Q+KEA+ + + ++ EE+ L Sbjct: 122 ------------ESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKL 169 Query: 308 PEIREKIEDAKESQR--SGNVAELALKATLVESS 339 I +E A+E G V +L + +++ + Sbjct: 170 VIIESDLERAEERAELSEGQVRQLEEQLRIMDQT 203 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 44.3 bits (103), Expect = 2e-04 Identities = 55/234 (23%), Positives = 100/234 (42%), Gaps = 42/234 (17%) Query: 115 VEEEEG----EKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170 V++ EG + ++E L+E + E G E+ + E M ND +++L +N E Sbjct: 487 VQDNEGLSRLNREQEERLLEL-ERAAELWG-EQAEARRQILETMQNDRTTISRALSQNRE 544 Query: 171 --EEIGNLE-----LAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAV 223 E++ L+ L + +++ + Q K + KLGE+ + + V Sbjct: 545 LKEQLAELQSGFVKLTNENMEITSALQSEQHVKR------ELGKKLGELQEKLSELKETV 598 Query: 224 E----EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRM 279 E E QS ++QYL G+ QY A Q + EV+ N++ Sbjct: 599 ELKSQEAQSLQQQRDQYL------------------GHLQQYVAAYQQLTSEKEVLHNQL 640 Query: 280 AVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333 + + V + + A+ K E ++ L E +E++E A + Q A+L+L A Sbjct: 641 LLQTQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQ-QNQQLRAQLSLMA 693 Score = 38.1 bits (87), Expect = 0.016 Identities = 78/333 (23%), Positives = 138/333 (41%), Gaps = 53/333 (15%) Query: 92 GKSLLELARMENGVLGNALEGVHVEEEEGEKTEDE-SLVENNDNIDETEGSEEDDKENDK 150 GK++ E+AR E L E + ++ ++ + SL+ + D + EE+D+E ++ Sbjct: 657 GKAVAEMARQE---LQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDEEEEE 713 Query: 151 TEEM----PNDSVLE------------NKSLQENEEEEI---GNL-ELAWDMLDLAKIIF 190 E + P S+ E N ++ EEE+ G L E LA ++ Sbjct: 714 EEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAHLLA 773 Query: 191 KRQETKEAQLYAAQAHLKLGE-VSVESENYVQ-AVEEFQS-CLNLQEQYLEAHDRLLAET 247 Q+ EA AA A G+ V E+ +Q A+E+ QS + L ++ + +R+ Sbjct: 774 SAQKEPEA---AAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELE 830 Query: 248 HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELL 307 H + L+ G E +A + +++ AVL E+ +E E + ++ EE+K L Sbjct: 831 HRCIQLS-GETDTIGEYIALY-------QSQRAVLKERHREKEEYISRLAQDKEEMKVKL 882 Query: 308 PEIREKIEDAKESQRSGNVAELALKATLVESSTSG---------FTPGGGGSSVSMIASR 358 E++E + + + LA + TSG G VS+ S Sbjct: 883 LELQELVLRLVGDRNEWHGRFLAAAQNPADEPTSGAPAPQELGAANQQGDLCEVSLAGSV 942 Query: 359 KPTDGASSSNCVTD------ISHLVRKKRKPEE 385 +P G + D I L+R+ + P E Sbjct: 943 EPAQGEAREGSPRDNPTAQQIMQLLREMQNPRE 975 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/237 (20%), Positives = 102/237 (43%), Gaps = 19/237 (8%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKEN-DKTEEMPNDSVLENKSLQ 166 N+L+ EEEE K ++ ++ + +T+ +DD + EE + + ++L Sbjct: 1346 NSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALS 1405 Query: 167 ENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEF 226 + EE+ LA+D L+ K + QE + + + + + + Q + E Sbjct: 1406 QRLEEKA----LAYDKLEKTKNRLQ-QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEE 1460 Query: 227 QSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVA----------QFSKSIEVIE 276 +S + +Y E DR AE + A +EA+ Q +E + Sbjct: 1461 KS---ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517 Query: 277 NRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKA 333 + + + V E E S ++++EE++ L E+ ++++ ++++ V A+KA Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKA 1574 Score = 38.9 bits (89), Expect = 0.010 Identities = 45/244 (18%), Positives = 109/244 (44%), Gaps = 29/244 (11%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEE--DDKENDKTEEMPNDS-----VLENK----- 163 E E+ K+ + +++ + + +E + + + ++ +E+ N + +L+ K Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEA 1736 Query: 164 ---SLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYV 220 L+E EEE N+EL D + + +T A+L A ++ + +S+N Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTL---QVDTLNAELAAERS------AAQKSDNAR 1787 Query: 221 QAVEEFQSCLNLQEQYLEAHDR-----LLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVI 275 Q +E L + Q LE + ++ ++G Q + A +K + Sbjct: 1788 QQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847 Query: 276 ENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATL 335 E ++ + QV++ + +YK+++E+ + +++ ++E+A+E N + L+ L Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907 Query: 336 VESS 339 +++ Sbjct: 1908 DDAT 1911 Score = 36.2 bits (82), Expect = 0.062 Identities = 47/233 (20%), Positives = 91/233 (39%), Gaps = 21/233 (9%) Query: 106 LGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSL 165 L ALE +EE E+ + + D + + ++ E +K++ V E ++ Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547 Query: 166 QENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE 225 E E+E+ E A L++ K Q ++ Q Q EE Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN------------------EE 1589 Query: 226 FQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQ 285 + L Q + LEA L + Q LA + + + IE + +Q Sbjct: 1590 KKRLLIKQVRELEAE---LEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646 Query: 286 VKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVES 338 +++ + +Y++E+EE + EI + +++++ +S L L+ L S Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASS 1699 Score = 33.1 bits (74), Expect = 0.53 Identities = 69/352 (19%), Positives = 135/352 (38%), Gaps = 40/352 (11%) Query: 93 KSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTE 152 K LE E L+ V E E K D + E + + +EG + +K Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKV--SEGDRLRVELAEKAS 1283 Query: 153 EMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQET-KEAQLYAAQAHLKLGE 211 ++ N+ L+N S E E+ G ++ A D L + QE +E ++ + Sbjct: 1284 KLQNE--LDNVSTLLEEAEKKG-IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340 Query: 212 VSVESENYV-QAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSK 270 + E + Q EE ++ NL++Q L +L A+T ++ G +EA + K Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL-ADTKKKVDDDLGTIESLEEAKKKLLK 1399 Query: 271 SIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGN---VA 327 E + R+ + E + ++E+++L L R+ + ++ Q+ + Sbjct: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE 1459 Query: 328 ELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEES 387 E ++ A E R + ++ + + + +EE Sbjct: 1460 EKSISARYAEE-----------------RDRAEAEAREKETKALSLARALEEALEAKEEF 1502 Query: 388 PRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVE 439 R++ +A E D + S ++V +N+ E +S+ A+E VE Sbjct: 1503 ERQNKQLRADME--------DLMSSKDDVGKNVHE----LEKSKRALEQQVE 1542 Score = 32.0 bits (71), Expect = 1.2 Identities = 19/87 (21%), Positives = 40/87 (45%) Query: 233 QEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGS 292 QE+ L+A D L + + G + + Q + ++ ++ E EAE Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909 Query: 293 SAEYKKEIEELKELLPEIREKIEDAKE 319 A + +EL+E+L ++ ++E+ +E Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEE 936 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 44.3 bits (103), Expect = 2e-04 Identities = 43/218 (19%), Positives = 97/218 (44%), Gaps = 27/218 (12%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEG--SEEDDKENDKTEEMPNDSVLENKSL 165 +AL+ ++ +E + L E + ID+ G SE+ DK ++ +++ N + + + Sbjct: 1763 DALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKI 1822 Query: 166 QENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAV-- 223 QE + E + L D+ + K + + ++ K+ L L ++ +E+ N Q + Sbjct: 1823 QELKANEHQLITLKKDVNETQKKVSEMEQLKKQ---IKDQSLTLSKLEIENLNLAQKLHE 1879 Query: 224 --EEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAV 281 EE +S + ++ + L E Q +S++ + R Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERD------------------QLKESLQETKARDLE 1921 Query: 282 LNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319 + +++K A S E+K+ +++L+E + E +I D ++ Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQK 1959 Score = 38.1 bits (87), Expect = 0.016 Identities = 48/236 (20%), Positives = 97/236 (41%), Gaps = 30/236 (12%) Query: 114 HVEEE-EGEKTEDESLVENNDNI-----DETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 H++E+ E +K E++ N + + E KE D + +E L+E Sbjct: 1648 HLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKE 1707 Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227 N E I R K+ +L HLK + +++ + + E+ Sbjct: 1708 NLRETI-----------------TRDLEKQEELKIVHMHLKEHQETIDKLRGIVS-EKTN 1749 Query: 228 SCLNLQEQYLEAHDRLLAET---HYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNE 284 N+Q+ ++D L A+ +L +A+ + + E + K ++ + L+ Sbjct: 1750 EISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI---DKLRGIVSEKTDKLSN 1806 Query: 285 QVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340 K+ E S+A+ +++I+ELK ++ +D E+Q+ + E K +S T Sbjct: 1807 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862 Score = 35.8 bits (81), Expect = 0.081 Identities = 38/231 (16%), Positives = 101/231 (43%), Gaps = 26/231 (11%) Query: 116 EEEEGEKTEDESLVENNDNIDE--------TEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 +E + KT E+L +D + E + S+ +++ +E N++ +++ Sbjct: 1349 KERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQ 1408 Query: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227 + ++ L + +ML L+K + ++H ++ V+ E ++ + E Q Sbjct: 1409 FKPKDSALLRIEIEMLGLSKRL-------------QESHDEMKSVAKEKDDLQRLQEVLQ 1455 Query: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVK 287 S + ++ ++ ET +L +A+ + +E + + ++ E ++ + +Q++ Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE 1515 Query: 288 EAEGSSAEYKKEIEELKEL-----LPEIREKIEDAKESQRSGNVAELALKA 333 +EI E +E + E++EK+ + K+ + + AL++ Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQS 1566 Score = 35.4 bits (80), Expect = 0.11 Identities = 45/239 (18%), Positives = 100/239 (41%), Gaps = 19/239 (7%) Query: 111 EGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEE 170 E + +E ++ + +++ N D ++ + E K++ +T + E S + E Sbjct: 939 ESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHME 998 Query: 171 EEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEE----- 225 E G + + + I K+Q+ + A +K E+ + ++E Sbjct: 999 ENTGETKDEFQQKMVG--IDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056 Query: 226 --FQSCLNLQEQY---LEAHDRLLAETHYQLGLAYGYNSQYDEAVAQ-----FSKSIEVI 275 +S + +EQ L+ + + E +L L + E VAQ K E+ Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116 Query: 276 E--NRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALK 332 +R+A + E++KE E ++++ ++E + E+++KI + + + EL L+ Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175 Score = 34.3 bits (77), Expect = 0.24 Identities = 42/226 (18%), Positives = 91/226 (40%), Gaps = 18/226 (7%) Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNL 176 E EG+ T+ + E N ++E E E+ + + +P++ K +Q+ EE L Sbjct: 717 ELEGKITDLQK--ELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEE----L 770 Query: 177 ELAWDMLDLAKIIFKRQETKEAQLYAAQAHL--KLGEVSVESENYVQAVEEFQSCLNLQE 234 + D +F KE+++ + +++ NY +EFQ+ L Sbjct: 771 HIITSEKDK---LFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHM 827 Query: 235 QYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSA 294 + + + +L E + + +F S+ ++ ++ ++++E Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKE----AQKFDSSLGALKTELSYKTQELQEKTREVQ 883 Query: 295 EYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESST 340 E E+E+LKE ++ + + +R + L+ TL E T Sbjct: 884 ERLNEMEQLKE---QLENRDSTLQTVEREKTLITEKLQQTLEEVKT 926 Score = 33.5 bits (75), Expect = 0.40 Identities = 51/247 (20%), Positives = 106/247 (42%), Gaps = 41/247 (16%) Query: 114 HVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLE---------NKS 164 H+ E + E +S E + N+ E + +E ++ + P DS L +K Sbjct: 1371 HIRETLAKIQESQSKQEQSLNMKEKD-NETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1429 Query: 165 LQENEEE------EIGNLELAWDML---------DLAKIIFKRQETKEAQLYAAQAHLKL 209 LQE+ +E E +L+ ++L ++ +I+ K ET+E +L A LK Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEE-ELKVAHCCLKE 1488 Query: 210 GEVSV--------ESENYVQAVEEFQSCLN------LQEQYLEAHDRLLAETHYQLGLAY 255 E ++ E E + +++ +N +QE Y E ++ + ++ Sbjct: 1489 QEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIY-EKEEQFNIKQISEVQEKV 1547 Query: 256 GYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315 Q+ E +++ IE++M L +++E++ KE EE+K + ++ + + Sbjct: 1548 NELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607 Query: 316 DAKESQR 322 KE+ + Sbjct: 1608 QLKENTK 1614 Score = 31.6 bits (70), Expect = 1.5 Identities = 32/189 (16%), Positives = 85/189 (44%), Gaps = 15/189 (7%) Query: 116 EEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGN 175 E+ EK E E ++ +++DE E E K++ + + + S L+N + E+ N Sbjct: 515 EQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLV----KHAEVYN 570 Query: 176 LELAWDMLDLAKIIFKRQETKEAQLYAAQAHL---KLGEVSVESENYVQAVEEFQSCLNL 232 +L ++ +++ KE Q+ Q ++ KL + ++ ++++E+ + Sbjct: 571 QDLENELSSKVELL----REKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQ---- 622 Query: 233 QEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGS 292 +Q L + + + + N + E + + + + + +EN + + Q++ + Sbjct: 623 MKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKM 682 Query: 293 SAEYKKEIE 301 + +KE++ Sbjct: 683 QVDLEKELQ 691 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%) Query: 212 VSVESENYVQAVEEFQSCLNLQEQYLEAHDRL----LAETHY---QLGLAYGYNSQYDEA 264 + +E E Y + E + L ++ +E + + E+H Q+ ++ + Q E Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191 Query: 265 VAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSG 324 + +K IE + L ++++AE + Y E+ ELK+LL E+++K++D+ Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251 Query: 325 NVAELALKATLVESST 340 N LKA L E+ T Sbjct: 1252 NEELNLLKAQLNETLT 1267 Score = 30.8 bits (68), Expect = 2.6 Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%) Query: 155 PNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQL----YAAQAHL--- 207 P++ +L K + E E+E G W+ LD K + Q K L + A L Sbjct: 993 PHEELL--KVISEREKEISG----LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALAST 1046 Query: 208 ------KLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLG-LAYGYNSQ 260 K+ + S E + V+AVE L +E + ++ ++ G +G+ + Sbjct: 1047 EKMLQDKVNKTSKERQQQVEAVE-----LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKK 1101 Query: 261 YDEAVAQFSKS--IEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315 E +A S S ++V+E+++ +E + +YK + E + +L +++ +E Sbjct: 1102 AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 43.9 bits (102), Expect = 3e-04 Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 7/136 (5%) Query: 212 VSVESENYVQAVEEFQSCLNLQEQYLEAHDRL----LAETHY---QLGLAYGYNSQYDEA 264 + +E E Y + E + L ++ +E + + E+H Q+ ++ + Q E Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191 Query: 265 VAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSG 324 + +K IE + L ++++AE + Y E+ ELK+LL E+++K++D+ Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251 Query: 325 NVAELALKATLVESST 340 N LKA L E+ T Sbjct: 1252 NEELNLLKAQLNETLT 1267 Score = 30.8 bits (68), Expect = 2.6 Identities = 39/177 (22%), Positives = 77/177 (43%), Gaps = 27/177 (15%) Query: 155 PNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQL----YAAQAHL--- 207 P++ +L K + E E+E G W+ LD K + Q K L + A L Sbjct: 993 PHEELL--KVISEREKEISG----LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALAST 1046 Query: 208 ------KLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLG-LAYGYNSQ 260 K+ + S E + V+AVE L +E + ++ ++ G +G+ + Sbjct: 1047 EKMLQDKVNKTSKERQQQVEAVE-----LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKK 1101 Query: 261 YDEAVAQFSKS--IEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315 E +A S S ++V+E+++ +E + +YK + E + +L +++ +E Sbjct: 1102 AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1158 >gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] Length = 185 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 2/65 (3%) Query: 108 NALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQE 167 +A +G+ VEEEE E+ E+E VE + +E E EE++++ ++ EE + E K ++E Sbjct: 111 SAQQGLPVEEEEVEEEEEE--VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168 Query: 168 NEEEE 172 + EE Sbjct: 169 EKVEE 173 Score = 41.2 bits (95), Expect = 0.002 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%) Query: 107 GNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKSLQ 166 G +E VEEEE E E+E E + DE E +E++KE D+ EE +E + ++ Sbjct: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEE--DEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172 Query: 167 ENEEEEI 173 E + EI Sbjct: 173 EEIDTEI 179 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 43.9 bits (102), Expect = 3e-04 Identities = 50/242 (20%), Positives = 109/242 (45%), Gaps = 16/242 (6%) Query: 93 KSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDK-T 151 +S L+ MEN L LE + + + E+ E E N ET E+D K+ +K Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE----NKSLEQETSQLEKDKKQLEKEN 838 Query: 152 EEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFK------RQETKEAQLYAAQA 205 + + + +++ +L+EN + IGNLE L I+K ++ KE + +A Sbjct: 839 KRLRQQAEIKDTTLEENNVK-IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897 Query: 206 HLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY---- 261 + + + E+ V + Q N E+ +++ L + +Y Sbjct: 898 TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE 957 Query: 262 DEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQ 321 + + KS+E+ E ++A L +++E+ + + ++E++ +K+ ++++ ++ + Q Sbjct: 958 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQ 1017 Query: 322 RS 323 S Sbjct: 1018 SS 1019 Score = 38.1 bits (87), Expect = 0.016 Identities = 46/233 (19%), Positives = 94/233 (40%), Gaps = 30/233 (12%) Query: 117 EEEGEKTEDESLVENNDNIDETEGSEEDDK-----ENDKTEEMPNDSVLENKSL--QENE 169 E + ++ + E L+E N ++ + D+ E ++ S KSL + NE Sbjct: 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNE 456 Query: 170 EEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGE--------VSVESENYVQ 221 L+L + L K + + + T ++ A LK+ + V + VQ Sbjct: 457 LTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ 516 Query: 222 AVEEFQSCLNLQEQYLEAH-------DRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEV 274 + Q+C NL + ++ + L + Q+ + N ++ V+ + ++ Sbjct: 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576 Query: 275 --------IENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKE 319 IE +L+E +KE ++ + E ++K+ L +EK E A+E Sbjct: 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629 Score = 37.4 bits (85), Expect = 0.028 Identities = 39/213 (18%), Positives = 96/213 (45%), Gaps = 26/213 (12%) Query: 105 VLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSVLENKS 164 +L + LEG ++ + E E+L + + + E E D + K EE+ +++ + Sbjct: 362 MLEDQLEGTRARSDKLHELEKENL-QLKAKLHDME--MERDMDRKKIEELMEENMTLEMA 418 Query: 165 LQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQ--AHLKLGEVSVESENYVQA 222 +++ +E +L L W++ +++ + +++ + +L ++ +E+++ + Sbjct: 419 QKQSMDE---SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT 475 Query: 223 VEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVL 282 VEE ++ ++ E A L E Q + SK +E++EN + Sbjct: 476 VEELRTTVDSVEG--NASKILKMEKENQ----------------RLSKKVEILENEIVQE 517 Query: 283 NEQVKEAEGSSAEYKKEIEELKELLPEIREKIE 315 + ++ + S + KE +L++ + +RE E Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550 Score = 36.2 bits (82), Expect = 0.062 Identities = 48/215 (22%), Positives = 93/215 (43%), Gaps = 25/215 (11%) Query: 136 DETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDML----DLAKIIFK 191 + T S+ N + + S LEN++ +E E +L+ +D L + +++ + Sbjct: 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE--DLKSLYDSLIKDHEKLELLHE 1167 Query: 192 RQETKEAQLYAAQAHLKLGEVSVESEN------YVQAVEEFQSCLNLQEQYLEAHDRLLA 245 RQ ++ L + LK ++E E+ Y Q +++ +L++ +++L Sbjct: 1168 RQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 1227 Query: 246 ET--HYQLGLAY----GYNSQYDEAVAQFSKSIEVIE----NRMAVLNEQVKEAEGSSAE 295 E H + Y G N + + +Q K EV++ N ++LN E AE Sbjct: 1228 ENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287 Query: 296 YKKEIEELKELLPEIREKIEDAKE--SQRSGNVAE 328 + K ++E + L K+ + E SQ GN+ E Sbjct: 1288 FSK-LKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1321 Score = 32.0 bits (71), Expect = 1.2 Identities = 42/235 (17%), Positives = 98/235 (41%), Gaps = 22/235 (9%) Query: 100 RMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDETEGSEEDDKENDKTEEMPNDSV 159 R E + E + ++E + + DN E E S+E +E K ++ + Sbjct: 993 RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE-SQETTRELLKVKDRLIEVE 1051 Query: 160 LENKSLQENEEE---EIGNLELAWDMLDLAKIIFKRQ-----------ETKEAQLYAAQA 205 N +LQ ++ ++ LE + L + +RQ +T+ A+L + Sbjct: 1052 RNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111 Query: 206 HLKLGEVSVESENYVQAVE------EFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNS 259 L S+ ++N ++ E +S + +E +D L+ + H +L L + + Sbjct: 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQA 1170 Query: 260 QYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKI 314 E++ +++ + V + +++ + K ++E+L+++L +EK+ Sbjct: 1171 SEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.122 0.319 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,765,780 Number of Sequences: 37866 Number of extensions: 756274 Number of successful extensions: 10118 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 315 Number of HSP's successfully gapped in prelim test: 688 Number of HSP's that attempted gapping in prelim test: 5318 Number of HSP's gapped (non-prelim): 3924 length of query: 449 length of database: 18,247,518 effective HSP length: 106 effective length of query: 343 effective length of database: 14,233,722 effective search space: 4882166646 effective search space used: 4882166646 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.