Guide to the Human Genome
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Name: ROCK1 Sequence: fasta or formatted (1354aa) NCBI GI: 4885583
Description:

Rho-associated, coiled-coil containing protein kinase 1

Referenced in:

Coiled-Coil Proteins
Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         71           2
 C cysteine            1.3         18           1
 D aspartate           6.6         89           2
 E glutamate          11.7        158           3
 F phenylalanine       3.1         42           2
 G glycine             3.1         42           2
 H histidine           2.1         28           1
 I isoleucine          3.6         49           1
 K lysine             10.0        136           2
 L leucine            10.6        143           3
 M methionine          2.9         39           1
 N asparagine          6.0         81           2
 P proline             2.5         34           3
 Q glutamine           6.0         81           2
 R arginine            6.0         81           2
 S serine              6.2         84           2
 T threonine           4.5         61           1
 V valine              5.2         70           3
 W tryptophan          0.8         11           2
 Y tyrosine            2.7         36           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho-associated, coiled-coil containing protein kinase... 
ROCK2                 0.653   Rho-associated, coiled-coil containing protein kinas...
CDC42BPB              0.172   CDC42-binding protein kinase beta 
CDC42BPA              0.169   CDC42-binding protein kinase alpha isoform B 
CDC42BPA              0.159   CDC42-binding protein kinase alpha isoform A 
CDC42BPG              0.154   CDC42 binding protein kinase gamma (DMPK-like) [Hom...
CIT                   0.153   citron 
DMPK                  0.128   myotonic dystrophy protein kinase isoform 4 
DMPK                  0.128   myotonic dystrophy protein kinase isoform 3 
DMPK                  0.127   myotonic dystrophy protein kinase isoform 2 
DMPK                  0.121   myotonic dystrophy protein kinase isoform 1 
LOC727758             0.107   PREDICTED: similar to Rho-associated, coiled-coil c...
LOC727758             0.086   PREDICTED: similar to Rho-associated, coiled-coil c...
PRKACB                0.076   cAMP-dependent protein kinase catalytic subunit beta...
PRKACB                0.076   cAMP-dependent protein kinase catalytic subunit beta ...
MAST1                 0.074   microtubule associated serine/threonine kinase 1 [Ho...
PRKACA                0.074   cAMP-dependent protein kinase catalytic subunit alph...
PRKACA                0.074   cAMP-dependent protein kinase catalytic subunit alpha...
MAST4                 0.074   microtubule associated serine/threonine kinase fami...
PRKACG                0.074   protein kinase, cAMP-dependent, catalytic, gamma [Ho...
MAST3                 0.073   microtubule associated serine/threonine kinase 3 [H...
MAST2                 0.072   microtubule associated serine/threonine kinase 2 [H...
PRKX                  0.072   protein kinase, X-linked 
PRKCH                 0.067   protein kinase C, eta 
PRKCE                 0.066   protein kinase C, epsilon 
PRKCB                 0.066   protein kinase C, beta isoform 1 
PRKG1                 0.066   protein kinase, cGMP-dependent, type I isoform 1 [H...
PRKG1                 0.066   protein kinase, cGMP-dependent, type I isoform 2 [Ho...
AKT2                  0.065   AKT2 kinase 
PRKCQ                 0.065   protein kinase C, theta 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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